A strain of *Duboscirella nymphoides* TZF-002 and its application in the fermentation and conversion of rare ginsenosides.
By using Dubois nystomatitis TZF-002 fermentation and high-temperature steam treatment, the problem of low content of rare ginsenosides has been solved, and a variety of rare ginsenosides have been efficiently prepared, which has broad application prospects in medicine, health products and cosmetics.
CN121718476BActive Publication Date: 2026-05-26JILIN AGRICULTURAL UNIV
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Patent Information
- Application Number
- CN202610193274.X
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2026-02-10
- Publication Date
- 2026-05-26
- Estimated Expiration
- 2046-02-10
AI Technical Summary
Technical Problem
In existing technologies, natural ginseng contains extremely low levels of rare ginsenosides. Traditional preparation techniques are inefficient, complex, and polluting, making industrial application difficult.
Method used
Rare ginsenosides Rg6, F4, Rh4, S-Rg3, R-Rg3, Rk1, and Rg5 were prepared by fermentation and high-temperature steam treatment using Dubosiella newyorkensis TZF-002.
Benefits of technology
It significantly increased the content and variety of rare ginsenosides, and the prepared rare ginsenosides have significant biological activity, promoting the high-quality development of the ginseng industry.
✦ Generated by Eureka AI based on patent content.
Abstract
A strain of Dubois nystomatitis ( Dubosiella newyorkensis TZF-002 and its application in the fermentation and conversion of rare ginsenosides belong to the field of microbiology. The *Duboscirella nymphaeus* mentioned herein (…) Dubosiella newyorkensis TZF-002 was deposited at the China Center for Type Culture Collection on December 15, 2025, with accession number CCTCC NO: M 20252890. This invention uses total ginsenosides as raw material, first utilizing the high-β-glucosidase-producing *Duboscirella nystatin* (…). Dubosiella newyorkensis The TZF-002 method employs a mild and controlled fermentation process to transform primary ginsenosides, followed by high-temperature steam treatment, ultimately yielding rare ginsenosides Rg6, F4, Rh4, S-Rg3, R-Rg3, Rk1, and Rg5 efficiently. This method, for the first time, combines the enzymatic transformation characteristics of intestinal symbiotic bacteria with physical treatment, offering advantages such as mild conditions, low cost, and significantly superior product variety and content compared to single processes. It effectively improves the yield, bioavailability, and physiological activity of rare saponins.
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