Hair-loss-preventing hair-caring and hair-blackening hair-caring liquid and preparation method thereof

Abstract

The invention belongs to the technical field of hair care products, and particularly discloses an anti-hair-loss hair care and blackening hair care liquid and a preparation method thereof.The hair care liquid is prepared from, by mass, 6-18% of composite natural active ingredients, 2-6% of penetration enhancer, 3-8% of humectant, 0.5-2% of antioxidant, 0.3-1.0% of preservative, 0.05-0.2% of pH regulator and the balance deionized water; the composite natural active ingredients comprise a prepared polygonum multiflorum extract, an eclipta alba extract, a nigella nigra seed extract, a cacumen biotae extract, a cherokee rose fruit extract and an acanthopanax senticosus leaf extract; the preservative comprises a honeysuckle extract, a rosemary extract and a lemon extract. According to the hair-loss-preventing, hair-caring and hair-blackening hair-caring liquid and the preparation method thereof, the hair-caring liquid is compounded from natural active ingredients, is high in safety and free of side effects, can simultaneously achieve triple effects of preventing hair loss, nourishing and caring hair and improving white hair, and is lasting and stable in effect.

Description

Technical Field

[0001] This invention relates to the field of hair care product technology, and in particular to an anti-hair loss hair care and blackening hair liquid and its preparation method. Background Technology

[0002] With the fast pace of life, increased stress, environmental degradation, and aging, hair loss, dry and frizzy hair, and premature graying are becoming increasingly common, seriously affecting people's appearance and mental health. Currently, the market offers a wide variety of hair care products, but most suffer from limited functionality: some products only provide basic moisturizing and conditioning, failing to address hair loss and graying; some anti-hair loss products rely on chemical ingredients (such as minoxidil), which, while temporarily relieving hair loss, can cause strong irritation, dependency, and long-term use may lead to scalp allergies; and many hair-darkening products are essentially hair dyes, using chemicals to oxidize melanin, which not only fails to address the root cause of gray hair but may also damage the scalp and hair, and even pose a risk of cancer.

[0003] To address the aforementioned issues, developing a hair conditioner based on natural active ingredients that offers triple benefits—anti-hair loss, hair care, and hair darkening—while also being highly safe and free of side effects, holds significant market value. While existing technologies have attempted to combine multiple natural ingredients in hair care products, they generally suffer from problems such as unreasonable ingredient combinations, low utilization rates of active ingredients, and poor synergistic effects, resulting in insignificant anti-hair loss and hair darkening effects that are difficult to maintain long-term. For example, some solutions use ginger extract alone for anti-hair loss, but its active ingredient, gingerol, has poor stability and is easily volatile, leading to a short-lasting anti-hair loss effect; other solutions use processed Polygonum multiflorum extract for hair darkening, but single-ingredient effects are slow and require long-term, high-dose use to see results, while neglecting synergistic effects with other ingredients.

[0004] Therefore, how to improve the stability and utilization rate of active ingredients through reasonable ingredient compounding, and achieve synergistic enhancement of anti-hair loss, hair care and hair darkening effects, is a technical problem that urgently needs to be solved in this field. Summary of the Invention

[0005] The purpose of this invention is to provide a hair loss prevention and hair care liquid and its preparation method. The hair care liquid uses a compound of natural active ingredients, is highly safe and has no side effects. It can simultaneously achieve the triple effects of preventing hair loss, nourishing and protecting hair, and improving gray hair, and the effects are long-lasting and stable.

[0006] To achieve the above objectives, the present invention provides an anti-hair loss, hair care, and hair darkening liquid, comprising the following raw material components in the following weight percentages: 6-18% complex natural active ingredients, 2-6% penetration enhancer, 3-8% moisturizer, 0.5-2% antioxidant, 0.3-1.0% preservative, 0.05-0.2% pH adjuster, and the balance being deionized water; the complex natural active ingredients include processed Polygonum multiflorum extract, Eclipta prostrata extract, Nigella veitchii seed extract, Platycladus orientalis leaf extract, Rosa laevigata extract, and Acanthopanax senticosus leaf extract; the preservatives include Lonicera japonica extract, Rosemary extract, and Lemon extract.

[0007] Preferably, the mass ratio of processed Polygonum multiflorum extract, Eclipta prostrata extract, Nigella veitchii seed extract, Platycladus orientalis leaf extract, Rosa laevigata extract, and Acanthopanax senticosus leaf extract is 3:2:2:1:1:1.

[0008] Preferably, the penetration enhancer is a compound of laurocapram and propylene glycol in a weight ratio of 1:3.

[0009] Preferably, the moisturizer is hyaluronic acid.

[0010] Preferably, the antioxidant is vitamin E.

[0011] Preferably, the mass ratio of honeysuckle extract: rosemary extract: lemon extract is 1:1:1.

[0012] Preferably, the pH adjuster is triethanolamine.

[0013] This invention also provides a method for preparing an anti-hair loss, hair-protecting, and hair-darkening conditioner, comprising the following steps: Step 1: Mix the components of the compound natural active ingredients, add 0.5% natural dispersant, and shear in a high-speed shearing machine for 15 minutes to form a nano-scale pre-dispersion; mix the preservative with 2% propylene glycol, and ultrasonically disperse for 10 minutes to prepare a preservative premix. Step 2: Preheat deionized water to 70-75℃, inject hyaluronic acid through a metering pump while stirring at 300r / min, and simultaneously introduce nitrogen gas to prevent hyaluronic acid from oxidizing and degrading. After stirring for 30min, monitor the viscosity using an online viscometer. Step 3: Quickly cool the liquid from Step 2 to 55-60℃, transfer it to a vacuum homogenizer, first add the pre-dispersed liquid of the pre-treated composite natural active ingredients, maintain a vacuum state, increase the speed of the homogenizer to 5000 r / min, and homogenize for 20 min; then add the penetration promoter, reduce the speed to 3000 r / min, and continue homogenizing for 20 min. Step 4: Cool the system from Step 3 to 45-50℃, maintain a vacuum, add the antioxidant and the pretreated premixed anti-corrosion solution, and stir at 200r / min for 20min. Step 5: Continuously inject pH adjuster and monitor pH value in real time. When pH is stable, stop titration and continue stirring for 15 minutes. Step 6: First, filter the system obtained in Step 5 through a 5μm ceramic membrane to remove large particulate impurities, and then filter through a 0.22μm polyethersulfone membrane to remove fine impurities, thus obtaining the hair conditioner.

[0014] Preferably, in step 1, the natural dispersant is soybean lecithin.

[0015] Preferably, in step 5, the titration is stopped when the pH stabilizes at 5.5-6.5.

[0016] The advantages and beneficial effects of the above-mentioned anti-hair loss, hair-protecting, and hair-darkening liquid and its preparation method are as follows: 1. This invention achieves a synergistic enhancement of three effects—anti-hair loss, hair care, and hair darkening—through the compounding of complex natural active ingredients. It can simultaneously solve multiple problems such as hair loss, dry hair, and premature graying, and its effects are significantly better than single-effect products or products with unreasonable ingredient combinations.

[0017] 2. High safety and no side effects: This invention uses natural plant extracts as the core active ingredients, combined with mild excipients. The pH value matches the normal pH value of the scalp, with low irritation and no risk of allergies. It can be used for a long time, solving the problem of poor safety of existing chemical anti-hair loss and hair dye products.

[0018] 3. High utilization rate of active ingredients: This invention uses a penetration enhancer composed of lauryl azone and propylene glycol, which can effectively promote the penetration of active ingredients into the depths of hair follicles, improve the utilization rate of active ingredients, and enhance the lasting effect.

[0019] 4. Simple preparation process, easy to industrial production: The preparation process of this invention has clear steps and controllable parameters. It does not require complex equipment and high costs, making it suitable for large-scale industrial production.

[0020] The technical solution of the present invention will be further described in detail below through embodiments. Detailed Implementation

[0021] The technical solution of the present invention will be further described below through embodiments.

[0022] Unless otherwise defined, the technical or scientific terms used in this invention shall have the ordinary meaning as understood by one of ordinary skill in the art to which this invention pertains.

[0023] The following examples are not intended to limit the invention, but are only for illustration. Unless otherwise specified, the experimental methods used in the following examples are generally performed under conventional conditions. Unless otherwise specified, the materials and reagents used in the following examples are commercially available.

[0024] Example 1 A hair loss prevention and hair darkening conditioner comprises the following raw material components in the following weight percentages: 6-18% complex natural active ingredients, 2-6% penetration enhancer, 3-8% moisturizer, 0.5-2% antioxidant, 0.3-1.0% preservative, 0.05-0.2% pH adjuster, and the balance being deionized water. The complex natural active ingredients include processed Polygonum multiflorum extract, Eclipta prostrata extract, Nigella veitchii seed extract, Platycladus orientalis leaf extract, Rosa laevigata extract, and Acanthopanax senticosus leaf extract, with a weight ratio of 3:2:2:1:1:1. The preservatives include Lonicera japonica extract, Rosemary extract, and Lemon extract, with a weight ratio of 1:1:1.

[0025] The penetration enhancer is a compound of laurocapram and propylene glycol in a weight ratio of 1:3.

[0026] The moisturizer is hyaluronic acid.

[0027] The antioxidant is vitamin E.

[0028] The pH adjuster is triethanolamine.

[0029] The emodin and chrysophanol in processed Polygonum multiflorum extract have more stable activity after processing, and can more effectively promote the proliferation of melanocytes and melanin synthesis, thus improving gray hair from the root. The eclipta prostrata extract contains eclipta prostrata extract and flavonoids, which can significantly dilate scalp capillaries, increase blood perfusion to hair follicles, provide sufficient nutrition to hair follicles, inhibit hair follicle miniaturization, and strengthen the anti-hair loss effect. The unsaturated fatty acids and sterols in black cumin seed extract can deeply nourish hair cuticles, repair damaged hair, and improve dry, frizzy, and brittle hair. The flavonoids in Platycladus orientalis leaf extract have antibacterial and anti-inflammatory effects, which can relieve scalp inflammation and reduce the causes of hair loss. The tannins and vitamin C in Rosa laevigata extract can enhance the toughness of the tissues around hair follicles, delay hair follicle aging, and enhance the antioxidant capacity of the scalp. Eleutherococcus senticosus leaf extract contains eleutheroside and flavonoids, which can enhance the scalp's antioxidant capacity, inhibit free radical damage to hair follicles, and promote scalp blood circulation. It works synergistically with existing ingredients to improve anti-hair loss effects, relieve scalp fatigue, and improve sub-healthy scalp conditions. The synergistic effect of these ingredients achieves a combined enhancement of anti-hair loss, hair care, and hair darkening effects, solving the problems of limited efficacy of single ingredients and poor synergy in multi-ingredient formulations in existing technologies.

[0030] By using lauryl azone and propylene glycol as a penetration enhancer, lauryl azone can significantly reduce the barrier effect of the scalp stratum corneum and promote the penetration of active ingredients into the depth of hair follicles. Propylene glycol can not only enhance the penetration effect of lauryl azone, but also work synergistically with hyaluronic acid to moisturize, thus solving the problem of active ingredients being difficult to penetrate into hair follicles and having low utilization rate in existing technologies.

[0031] Honeysuckle extract contains chlorogenic acid and flavonoids, offering natural antibacterial and anti-inflammatory properties. It is biocompatible with the scalp, non-irritating, and can be combined with other natural preservatives to enhance its antibacterial spectrum. Rosemary extract contains rosmarinic acid and sauropic acid, providing a broad antibacterial spectrum (effective against both bacteria and fungi) and antioxidant effects, extending product shelf life. It is suitable for combination with honeysuckle extract (1:1 ratio) to synergistically enhance preservative effects. Lemon extract contains citric acid and citral, offering natural antibacterial properties and a refreshing scent. It can replace artificial fragrances for enhanced aromatherapy, resulting in a longer-lasting effect when used in combination.

[0032] A method for preparing an anti-hair loss, hair-protecting, and hair-darkening conditioner includes the following steps: Step 1: Mix the components of the compound natural active ingredients, add 0.5% of the natural dispersant soybean lecithin, and shear in a high-speed shearing machine for 15 minutes to form a nano-scale pre-dispersion; mix the preservative with 2% propylene glycol and ultrasonically disperse for 10 minutes to prepare a preservative premix.

[0033] Step 2: Preheat deionized water to 70-75℃, inject hyaluronic acid through a metering pump while stirring at 300r / min, and simultaneously introduce nitrogen gas to prevent oxidative degradation of hyaluronic acid. After stirring for 30min, monitor the viscosity using an online viscometer.

[0034] Step 3: Quickly cool the liquid from Step 2 to 55-60℃ and transfer it to a vacuum homogenizer. First, add the pre-dispersed liquid of the pre-treated composite natural active ingredients, maintain the vacuum state, increase the speed of the homogenizer to 5000 r / min, and homogenize for 20 min. Then add the penetration promoter, reduce the speed to 3000 r / min, and continue homogenizing for 20 min.

[0035] Step 4: Cool the system from Step 3 to 45-50℃, maintain a vacuum state, add the antioxidant and the pretreated premixed anti-corrosion solution, and stir at 200r / min for 20min.

[0036] Step 5: Continuously inject pH adjuster and monitor pH value in real time. When pH stabilizes at 5.5-6.5, automatically stop titration and continue stirring for 15 minutes.

[0037] Step 6: First, filter the system obtained in Step 5 through a 5μm ceramic membrane to remove large particulate impurities, and then filter through a 0.22μm polyethersulfone membrane to remove fine impurities, thus obtaining the hair conditioner.

[0038] Example 2 A hair loss prevention and hair darkening conditioner, with the following raw material components by weight percentage: The formula contains 8% compound natural active ingredients (the mass ratio of processed Polygonum multiflorum extract, Eclipta prostrata extract, Nigella veitchii seed extract, Platycladus orientalis leaf extract, Rosa laevigata extract, and Acanthopanax senticosus leaf extract is 3:2:2:1:1:1), 4% penetration enhancer (1 part laurocapram and 3 parts propylene glycol), 5% hyaluronic acid, 1% vitamin E, 0.3% preservative (the mass ratio of Lonicera japonica extract, Rosemary extract, and Lemon extract is 1:1:1), 0.1% triethanolamine, and 81.6% deionized water.

[0039] A method for preparing an anti-hair loss, hair-protecting, and hair-darkening conditioner includes the following steps: Step 1: Mix the components of the compound natural active ingredients, add 0.5% soybean lecithin, and shear in a high-speed shearing machine for 15 minutes to form a nano-scale pre-dispersion; mix the preservative with 2% propylene glycol and ultrasonically disperse for 10 minutes to prepare a preservative premix.

[0040] Step 2: Preheat deionized water to 70°C, inject hyaluronic acid through a metering pump while stirring at 300 rpm, and simultaneously introduce nitrogen gas to prevent oxidative degradation of hyaluronic acid. After stirring for 30 minutes, monitor the viscosity using an online viscometer.

[0041] Step 3: Quickly cool the liquid from Step 2 to 60°C and transfer it to a vacuum homogenizer. First, add the pre-dispersed liquid of the pre-treated composite natural active ingredients, maintain the vacuum state, increase the speed of the homogenizer to 5000 r / min, and homogenize for 20 min. Then, add the penetration promoter, reduce the speed to 3000 r / min, and continue homogenizing for 20 min.

[0042] Step 4: Cool the system from Step 3 to 50°C, maintain a vacuum, add the antioxidant and the pretreated premixed anti-corrosion solution, and stir at 200 rpm for 20 min.

[0043] Step 5: Continuously inject pH adjuster and monitor pH value in real time. When pH stabilizes at 6.0, automatically stop titration and continue stirring for 15 minutes.

[0044] Step 6: First, filter the system obtained in Step 5 through a 5μm ceramic membrane to remove large particulate impurities, and then filter through a 0.22μm polyethersulfone membrane to remove fine impurities, thus obtaining the hair conditioner.

[0045] Example 3 A hair loss prevention and hair darkening liquid, with the following raw material components by weight percentage: The formula contains 12% compound natural active ingredients (the mass ratio of processed Polygonum multiflorum extract, Eclipta prostrata extract, Nigella veitchii seed extract, Platycladus orientalis leaf extract, Rosa laevigata extract, and Acanthopanax senticosus leaf extract is 3:2:2:1:1:1), 5% penetration enhancer (1 part laurocapram and 3 parts propylene glycol), 7% hyaluronic acid, 1.5% vitamin E, 0.4% preservative (the mass ratio of Lonicera japonica extract, Rosemary extract, and Lemon extract is 1:1:1), 0.15% triethanolamine, and 73.95% deionized water.

[0046] A method for preparing an anti-hair loss, hair-protecting, and hair-darkening conditioner includes the following steps: Step 1: Mix the components of the compound natural active ingredients, add 0.5% soybean lecithin, and shear in a high-speed shearing machine for 15 minutes to form a nano-scale pre-dispersion; mix the preservative with 2% propylene glycol and ultrasonically disperse for 10 minutes to prepare a preservative premix.

[0047] Step 2: Preheat deionized water to 75°C, inject hyaluronic acid through a metering pump while stirring at 300 rpm, and simultaneously introduce nitrogen gas to prevent oxidative degradation of hyaluronic acid. After stirring for 30 minutes, monitor the viscosity using an online viscometer.

[0048] Step 3: Quickly cool the liquid from Step 2 to 55°C and transfer it to a vacuum homogenizer. First, add the pre-dispersed liquid of the pre-treated composite natural active ingredients, maintain the vacuum state, increase the speed of the homogenizer to 5000 r / min, and homogenize for 20 min. Then, add the penetration promoter, reduce the speed to 3000 r / min, and continue homogenizing for 20 min.

[0049] Step 4: Cool the system from Step 3 to 45°C, maintain a vacuum, add the antioxidant and the pretreated premixed anti-corrosion solution, and stir at 200 rpm for 20 min.

[0050] Step 5: Continuously inject pH adjuster and monitor pH value in real time. When pH stabilizes at 5.5, automatically stop titration and continue stirring for 15 minutes.

[0051] Step 6: First, filter the system obtained in Step 5 through a 5μm ceramic membrane to remove large particulate impurities, and then filter through a 0.22μm polyethersulfone membrane to remove fine impurities, thus obtaining the hair conditioner.

[0052] Example 4 A hair loss prevention and hair darkening liquid, with the following raw material components by weight percentage: The formula contains 10% compound natural active ingredients (the mass ratio of processed Polygonum multiflorum extract, Eclipta prostrata extract, Nigella veitchii seed extract, Platycladus orientalis leaf extract, Rosa laevigata extract, and Acanthopanax senticosus leaf extract is 3:2:2:1:1:1), 4% penetration enhancer (1 part laurocapram and 3 parts propylene glycol), 6% hyaluronic acid, 1.2% vitamin E, 0.7% preservative (the mass ratio of honeysuckle extract, rosemary extract, and lemon extract is 1:1:1), 0.1% triethanolamine, and 78% deionized water.

[0053] A method for preparing an anti-hair loss, hair-protecting, and hair-darkening conditioner includes the following steps: Step 1: Mix the components of the compound natural active ingredients, add 0.5% soybean lecithin, and shear in a high-speed shearing machine for 15 minutes to form a nano-scale pre-dispersion; mix the preservative with 2% propylene glycol and ultrasonically disperse for 10 minutes to prepare a preservative premix.

[0054] Step 2: Preheat deionized water to 72°C, inject hyaluronic acid through a metering pump while stirring at 300 rpm, and simultaneously introduce nitrogen gas to prevent oxidative degradation of hyaluronic acid. After stirring for 30 minutes, monitor the viscosity using an online viscometer.

[0055] Step 3: Quickly cool the liquid from Step 2 to 60°C and transfer it to a vacuum homogenizer. First, add the pre-dispersed liquid of the pre-treated composite natural active ingredients, maintain the vacuum state, increase the speed of the homogenizer to 5000 r / min, and homogenize for 20 min. Then, add the penetration promoter, reduce the speed to 3000 r / min, and continue homogenizing for 20 min.

[0056] Step 4: Cool the system from Step 3 to 48°C, maintain a vacuum, add the antioxidant and the pretreated premixed anti-corrosion solution, and stir at 200 rpm for 20 min.

[0057] Step 5: Continuously inject pH adjuster and monitor pH value in real time. When pH stabilizes at 6.0, automatically stop titration and continue stirring for 15 minutes.

[0058] Step 6: First, filter the system obtained in Step 5 through a 5μm ceramic membrane to remove large particulate impurities, and then filter through a 0.22μm polyethersulfone membrane to remove fine impurities, thus obtaining the hair conditioner.

[0059] Comparative Example 1 A hair loss prevention and hair darkening liquid, with the following raw material components by weight percentage: The mixture contains 10% compound natural active ingredients (the mass ratio of processed Polygonum multiflorum extract, Eclipta prostrata extract, and Platycladus orientalis leaf extract is 3:2:1), 4% penetration enhancer (1 part laurocapram and 3 parts propylene glycol), 6% hyaluronic acid, 1.2% vitamin E, 0.7% preservative (the mass ratio of honeysuckle extract, rosemary extract, and lemon extract is 1:1:1), 0.1% triethanolamine, and 78% deionized water. The preparation method is the same as in Example 4.

[0060] Comparative Example 2 A hair loss prevention and hair darkening liquid, with the following raw material components by weight percentage: The compound natural active ingredients consist of 10% (the mass ratio of processed Polygonum multiflorum extract, Eclipta prostrata extract, Nigella veitchii seed extract, Platycladus orientalis leaf extract, Rosa laevigata extract, and Acanthopanax senticosus leaf extract is 3:2:2:1:1:1), 4% penetration enhancer (lauronolactone only), 6% hyaluronic acid, 1.2% vitamin E, 0.7% preservative (the mass ratio of Lonicera japonica extract, Rosmarinus officinalis extract, and Lemon extract is 1:1:1), 0.1% triethanolamine, and 78% deionized water. The preparation method is the same as in Example 4.

[0061] Comparative Example 3 A hair loss prevention and hair darkening liquid, with the following raw material components by weight percentage: The mixture contains 10% compound natural active ingredients (the mass ratio of processed Polygonum multiflorum extract, Eclipta prostrata extract, Nigella veitchii seed extract, Platycladus orientalis leaf extract, Rosa laevigata extract, and Acanthopanax senticosus leaf extract is 1:1:1:1:1:1), 4% penetration enhancer (1 part laurocapram and 3 parts propylene glycol), 6% hyaluronic acid, 1.2% vitamin E, 0.7% preservative (the mass ratio of Lonicera japonica extract, Rosmarinus officinalis extract, and Lemon extract is 1:1:1), 0.1% triethanolamine, and 78% deionized water. The preparation method is the same as in Example 4.

[0062] Comparative Example 4 We selected a commercially available brand of anti-hair loss hair care liquid. Its main ingredients are: minoxidil, glycerin, fragrance, and preservatives.

[0063] Comparative Example 5 A hair loss prevention and hair darkening liquid, with the following raw material components by weight percentage: The compound natural active ingredients consist of 10% (the mass ratio of processed Polygonum multiflorum extract, Eclipta prostrata extract, Nigella veitchii seed extract, Platycladus orientalis leaf extract, Rosa laevigata extract, and Acanthopanax senticosus leaf extract is 3:2:2:1:1:1), 4% penetration enhancer (1 part laurocapram and 3 parts propylene glycol), 6% hyaluronic acid, 1.2% vitamin E, 0.7% preservative (phenoxyethanol), 0.1% triethanolamine, and 78% deionized water. The preparation method is the same as in Example 4.

[0064] Comparative Example 6 A hair loss prevention and hair darkening liquid, with the following raw material components by weight percentage: The mixture contains 10% compound natural active ingredients (the mass ratio of processed Polygonum multiflorum extract, Eclipta prostrata extract, Nigella veitchii seed extract, Platycladus orientalis leaf extract, Rosa laevigata extract, and Acanthopanax senticosus leaf extract is 3:2:2:1:1:1), 4% penetration enhancer (1 part laurocapram and 3 parts propylene glycol), 6% hyaluronic acid, 1.2% vitamin E, 0.7% preservative (single honeysuckle extract), 0.1% triethanolamine, and 78% deionized water. The preparation method is the same as in Example 4.

[0065] Comparative Example 7 The preparation method differs from Example 4 in that it includes the following steps, while the rest is the same as in Example 4: 1. Weigh 78% deionized water and add it to a single-batch mixing tank. Heat the mixture to 70-75℃ and add hyaluronic acid while stirring at 300r / min. Stir for 30min until dissolved to obtain an aqueous solution. Allow the mixture to cool naturally to 55-60℃ and add the untreated compound natural active ingredients and penetration enhancer directly. Stir at 200r / min for 40min.

[0066] 2. Allow the solution to cool naturally to 45-50℃, add vitamin E and untreated natural preservatives, and stir at 200r / min for 20min; add triethanolamine manually to adjust the pH to 6.0, and stir for 15min; cool to room temperature, and filter using a single 0.22μm filter membrane to obtain the hair conditioner.

[0067] 150 volunteers aged 30-40 years with hair loss, dry hair, and a small amount of gray hair were selected and randomly divided into 5 groups of 30 people each. Each group used the hair care products of Example 2, Example 3, Example 4, and Comparative Examples 1-6 respectively. Another 30 volunteers used the product of Comparative Example 7 as a control.

[0068] All volunteers used the corresponding hair conditioner once daily, applying 5ml evenly to the scalp and hair each time, massaging for 5 minutes, for a total of 3 months. The following indicators were tested before use, after 1 month of use, and after 3 months of use: the test results are shown in Tables 1 and 2.

[0069] Hair loss prevention effect: The hair loss counting method was used to collect the number of hairs lost after each shampoo and calculate the average number of hairs lost in each group of volunteers.

[0070] Hair care effect: The hair moisture content test (using a hair moisture meter) and sensory evaluation (evaluating hair smoothness and softness) were used. The sensory evaluation was scored on a scale of 1 to 5, with 5 being the best.

[0071] Hair darkening effect: The change in the number of gray hairs in each group of volunteers was statistically analyzed, and the gray hair reduction rate was calculated (gray hair reduction rate = (number of gray hairs before use - number of gray hairs after use) / number of gray hairs before use × 100%).

[0072] Safety: Observe whether volunteers experience allergic reactions such as redness, swelling, and itching on their scalp during use, and count the incidence of allergies.

[0073] Table 1 Test Results

[0074] Table 2 Test Results

[0075] The average amount of hair loss in Examples 2-4 was significantly lower than that in the comparative examples, indicating that the compound natural active ingredient formulation and the penetration enhancer formulation can effectively promote scalp blood circulation, nourish hair follicles, and inhibit hair loss. Comparative Example 1 lacked black cumin seed extract, Rosa laevigata extract, and Acanthopanax senticosus leaf extract, which prevented it from exerting its antibacterial, anti-inflammatory, and hair follicle-enhancing effects, resulting in a poor anti-hair loss effect. Comparative Example 2 used a single penetration enhancer, which resulted in poor penetration of the active ingredients and an unsatisfactory anti-hair loss effect. Comparative Example 3 had an improper ratio of compound natural active ingredients, which weakened the synergistic effect and made it less effective in preventing hair loss than the examples.

[0076] The average hair moisture content and sensory evaluation scores of Examples 2-4 were higher than those of the comparative examples, indicating that the compound ingredients of the present invention can effectively nourish the hair, improve the problem of dry and frizzy hair, and enhance the smoothness and softness of the hair; the commercially available product of Comparative Example 4 had the worst hair care effect because its main ingredients were anti-hair loss chemicals and it lacked moisturizing and nourishing ingredients.

[0077] The gray hair reduction rate of Examples 2-4 was significantly higher than that of the comparative examples, indicating that the compound natural active ingredients of the present invention can effectively promote melanin synthesis and improve the gray hair problem from the root cause; Comparative Example 1 had a weak hair-darkening effect due to the lack of key ingredients; and the commercially available product of Comparative Example 4 had no hair-darkening effect.

[0078] No allergic reactions were observed in Examples 2-4 and Comparative Examples 1-3 and 6-7, indicating that the present invention uses natural ingredients and has high safety. The commercially available product in Comparative Example 4 and Comparative Example 5 used chemical preservatives, which contained chemically irritating ingredients, and allergic reactions occurred.

[0079] While Comparative Example 6 (single honeysuckle extract) met safety standards, its antibacterial spectrum was narrow (only effective against Gram-positive bacteria), and the total bacterial count exceeded the standard after 6 months. Furthermore, due to the lack of synergistic components, its auxiliary effect on the efficacy of the active ingredients was weak (the rate of gray hair reduction and the water content were both lower than those in the example). In contrast, the honeysuckle extract (antibacterial and anti-inflammatory) and rosemary extract (broad-spectrum antibacterial and antioxidant) in the example worked synergistically to expand the antibacterial range (covering bacteria, molds, and yeasts) and protect the natural active ingredients from oxidation through the antioxidant effect of rosmarinic acid, achieving the dual value of "preservative and enhanced efficacy" and solving the pain points of "not long-lasting preservation and single function" of single natural preservatives.

[0080] Comparative Example 7, lacking "pre-dispersion + vacuum homogenization," resulted in the aggregation of complex natural active ingredients into large particles (≥1500nm in diameter). These particles could only remain on the hair surface and could not penetrate the scalp's stratum corneum to reach the hair follicles, leading to a significant reduction in its anti-hair loss and hair-darkening effects. In contrast, the improved process in Example 7, through nano-level pre-dispersion to break down component aggregation and vacuum homogenization to form a stable colloidal system, increased the utilization rate of active ingredients by more than 40%, resulting in significantly better efficacy than traditional processes. This represents a creative breakthrough in addressing the industry challenge of "difficulty in dispersing and penetrating natural ingredients." Comparative Example 7, using natural cooling and manual operation, was prone to air contamination, leading to oxidation of active ingredients (such as the degradation of emodin in processed Polygonum multiflorum), and uneven component dispersion, resulting in stratification after 6 months. The improved process, through rapid cooling, nitrogen protection, and vacuum homogenization, avoids oxidation and air bubble contamination. Simultaneously, two-stage filtration removes fine impurities, ensuring the product remains stratified and undiscolored for 18 months, extending the shelf life from 6-12 months with traditional processes to 18 months. This solves the key problems of "poor stability and short shelf life" in traditional batch processes.

[0081] Therefore, the present invention adopts the above-mentioned anti-hair loss, hair care and blackening hair liquid and its preparation method. Through the synergistic effect of various components, the synergistic enhancement of anti-hair loss, hair care and blackening effects is achieved, which solves the problems of limited efficacy of single components and poor synergy of multi-component compounding in the prior art.

[0082] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention and not to limit them. Although the present invention has been described in detail with reference to preferred embodiments, those skilled in the art should understand that modifications or equivalent substitutions can still be made to the technical solutions of the present invention, and these modifications or equivalent substitutions cannot cause the modified technical solutions to deviate from the spirit and scope of the technical solutions of the present invention.

Claims

1. A hair loss prevention, hair care, and hair darkening liquid, characterized in that, The raw material components include the following percentages by weight: 6-18% complex natural active ingredients, 2-6% penetration enhancer, 3-8% moisturizer, 0.5-2% antioxidant, 0.3-1.0% preservative, 0.05-0.2% pH adjuster, and the balance being deionized water; the complex natural active ingredients include processed Polygonum multiflorum extract, Eclipta prostrata extract, Nigella veitchii seed extract, Platycladus orientalis leaf extract, Rosa laevigata extract, and Acanthopanax senticosus leaf extract; the preservatives include Lonicera japonica extract, Rosemary extract, and Lemon extract.

2. The anti-hair loss, hair-protecting, and hair-darkening conditioner according to claim 1, characterized in that: The mass ratio of processed Polygonum multiflorum extract, Eclipta prostrata extract, Nigella veitchii seed extract, Platycladus orientalis leaf extract, Rosa laevigata extract, and Acanthopanax senticosus leaf extract was 3:2:2:1:1:

1.

3. The anti-hair loss, hair-protecting, and hair-darkening conditioner according to claim 1, characterized in that: The penetration enhancer is a compound of laurocapram and propylene glycol in a weight ratio of 1:

3.

4. The anti-hair loss and hair-darkening conditioner according to claim 1, characterized in that: The moisturizer is hyaluronic acid.

5. The anti-hair loss, hair-protecting, and hair-darkening conditioner according to claim 1, characterized in that: The antioxidant is vitamin E.

6. The anti-hair loss, hair-protecting, and hair-darkening conditioner according to claim 1, characterized in that: The mass ratio of honeysuckle extract, rosemary extract, and lemon extract is 1:1:

1.

7. The anti-hair loss, hair-protecting, and hair-darkening conditioner according to claim 1, characterized in that: The pH adjuster is triethanolamine.

8. A method for preparing an anti-hair loss, hair-protecting, and hair-darkening conditioner according to any one of claims 1-7, characterized in that, Includes the following steps: Step 1: Mix the components of the compound natural active ingredients, add 0.5% natural dispersant, and shear in a high-speed shearing machine for 15 minutes to form a nano-scale pre-dispersion; mix the preservative with 2% propylene glycol, and ultrasonically disperse for 10 minutes to prepare a preservative premix. Step 2: Preheat deionized water to 70-75℃, inject hyaluronic acid through a metering pump while stirring at 300r / min, and simultaneously introduce nitrogen gas to prevent hyaluronic acid from oxidizing and degrading. After stirring for 30min, monitor the viscosity using an online viscometer. Step 3: Quickly cool the liquid from Step 2 to 55-60℃, transfer it to a vacuum homogenizer, first add the pre-dispersed liquid of the pre-treated composite natural active ingredients, maintain a vacuum state, increase the speed of the homogenizer to 5000 r / min, and homogenize for 20 min; then add the penetration promoter, reduce the speed to 3000 r / min, and continue homogenizing for 20 min. Step 4: Cool the system from Step 3 to 45-50℃, maintain a vacuum, add the antioxidant and the pretreated premixed anti-corrosion solution, and stir at 200r / min for 20min. Step 5: Continuously inject pH adjuster and monitor pH value in real time. When pH is stable, stop titration and continue stirring for 15 minutes. Step 6: First, filter the system obtained in Step 5 through a 5μm ceramic membrane to remove large particulate impurities, and then filter through a 0.22μm polyethersulfone membrane to remove fine impurities, thus obtaining the hair conditioner.

9. The preparation method of the anti-hair loss, hair-protecting, and hair-darkening conditioner according to claim 8, characterized in that: In step 1, the natural dispersant is soybean lecithin.

10. The method for preparing an anti-hair loss, hair-protecting, and hair-darkening conditioner according to claim 8, characterized in that: In step 5, the titration is stopped when the pH stabilizes at 5.5-6.5.

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