Medicament dispensing device
By designing automated drug dispensing equipment, the problems of long dispensing time, low accuracy, and high radiation risk of Y-90 microspheres have been solved, enabling precise drug dispensing in any location, reducing the radiation risk to operators, and saving time.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-12-23
- Publication Date
- 2026-04-03
AI Technical Summary
Existing Y-90 microsphere drug dispensing technology suffers from problems such as long dispensing time, difficulty in ensuring accuracy, high risk of operator exposure to radiation, and the limitation of operation to fixed locations.
A drug dispensing device has been designed, including a dispensing component, a dilution component, and a controller. It adopts an automated process for drug dispensing, uses a shield to reduce radiation risk, and improves dispensing accuracy through a meter and a shaker. It supports operation in any location.
It achieves automated and precise drug dispensing, reduces the radiation risk to operators, and can be dispensed in any location, significantly saving time.
Smart Images
Figure CN121778243A_ABST
Abstract
Description
Technical Field
[0001] This application relates to the field of radiopharmaceutical repackaging technology, and in particular to repackaging equipment. Background Technology
[0002] Liver cancer is one of the most common malignant tumors. Yttrium-90 microsphere (Y-90) selective internal radiotherapy (SIRT) is a local treatment method for liver tumors, similar to transarterial chemoembolization (TACE). Y-90 microspheres consist of resin microspheres, glass microspheres, carbon microspheres, and other carrier matrices. Y-90 microspheres act on tumor tissue through radiotherapy, effectively controlling tumor growth with relatively little damage to surrounding normal tissues.
[0003] To achieve optimal efficacy in SIRT treatment, precise dispensing of Y-90 microspheres is a key factor in ensuring the effectiveness of internal radiation therapy. Currently, Y-90 drug dispensing is done manually in a glove box in the high-activity room of the nuclear medicine department, which has the following unavoidable problems: long dispensing time, difficulty in guaranteeing dispensing accuracy, additional radiation exposure to operators, and the limitation of dispensing to a fixed location. Summary of the Invention
[0004] Therefore, it is necessary to provide a drug dispensing device to address the problems of long dispensing time, difficulty in ensuring dispensing accuracy, additional exposure of operators to radiation, and the limitation of dispensing to fixed locations.
[0005] This application provides a drug dispensing device, comprising: a dispensing component, a dilution component, and a controller; the dispensing component is disposed within a shielded cavity, and includes a stock solution rack, a first metering device, a dispensing rack, a second metering device, and an electric suction pump. The first metering device measures the amount of liquid in the stock solution container placed on the stock solution rack, the second metering device measures the amount of liquid in the dispensing container placed on the dispensing rack, and the electric suction pump can extract the stock solution from the stock solution container and dispense it into the dispensing container; the dilution component includes a diluent rack, a third metering device, a dilution pipeline, and a first valve. The third metering device measures the amount of liquid in the diluent container placed on the diluent rack, the first end of the dilution pipeline is connected to the opening of the diluent container on the diluent rack, the second end of the dilution pipeline is connected to the dispensing component, and the first valve is installed on the dilution pipeline; the controller is communicatively connected to both the dispensing component and the dilution component.
[0006] In one embodiment, the dispensing assembly further includes a first shaker and a second shaker, wherein the first shaker is capable of shaking the original liquid container placed on the original liquid rack, and the second shaker is capable of shaking the dispensing container placed on the dispensing rack; the controller is communicatively connected to the first shaker and the second shaker respectively.
[0007] In one embodiment, the packaging rack can be a packaging and transfer mechanism including multiple compartments, each compartment being used to place a packaging container, the packaging and transfer mechanism being able to change the position of the packaging container; the controller is communicatively connected to the packaging and transfer mechanism.
[0008] In one embodiment, the dispensing and conveying mechanism includes a turntable dispensing mechanism or a roller conveyor dispensing mechanism.
[0009] In one embodiment, the turntable dispensing mechanism or the roller conveyor dispensing mechanism is detachably installed inside the shield cavity.
[0010] In one embodiment, the dispensing assembly further includes a second valve, a third valve, a fourth valve, and a fifth valve; wherein, the first valve port of the first valve is connected to the opening of the diluent container via the dilution pipeline; the second valve port of the first valve is connected to the first valve port of the second valve; the third valve port of the first valve is connected to the first valve port of the fifth valve; the second valve port of the second valve is connected to the first valve port of the third valve; the third valve port of the second valve is connected to the first port of the electric suction pump; the second port of the electric suction pump is connected to the first port of the fourth valve; the second valve port of the third valve is connected to the second port of the fourth valve; the third valve port of the third valve is connected to the first end of the first dispensing pipeline; the second end of the first dispensing pipeline is connected to the original liquid container; the third valve port of the fourth valve is connected to the second valve port of the fifth valve; the third valve port of the fifth valve is connected to the first end of the second dispensing pipeline; the second end of the second dispensing pipeline is connected to the dispensing container; and the controller is communicatively connected to the first valve, the second valve, the third valve, the fourth valve, and the fifth valve.
[0011] In one embodiment, the dispensing assembly further includes a first flow meter, a second flow meter, and a third flow meter; wherein the first flow meter is disposed on the first dispensing pipeline, the second flow meter is disposed between the second port of the electric suction pump and the first port of the fourth valve, and the third flow meter is disposed between the third valve port of the first valve and the first valve port of the fifth valve.
[0012] In one embodiment, the device further includes an extraction component comprising a syringe and a push-pull mechanism, the push-pull mechanism being connected to the pushing end of the syringe, the injection end of the syringe being connected to the fourth valve port of the fifth valve; the controller is communicatively connected to the push-pull mechanism.
[0013] In one embodiment, the dilution assembly further includes a third shaker that enables the dilution container placed on the dilution rack to shake.
[0014] In one embodiment, the controller includes an interactive screen.
[0015] The aforementioned drug dispensing equipment, through the cooperation of dispensing components, dilution components, and a controller, can automatically package the raw liquid placed into the equipment without manual intervention, significantly reducing dispensing time. Furthermore, the dispensing and dilution components include a first measuring device for measuring the liquid volume in the raw liquid container, a second measuring device for measuring the liquid volume in the dispensing container, and a third measuring device for measuring the liquid volume in the diluent container, thus achieving precise packaging of the raw liquid. Moreover, the dispensing component in this device is located within a shielded cavity, which effectively reduces the risk of radiation exposure to personnel from the radioactive raw liquid and allows for dispensing in any location, eliminating the need for a fixed location. Attached Figure Description
[0016] Figure 1 One of the structural schematic diagrams of a drug dispensing device according to an embodiment of this application is shown.
[0017] Figure 2 A schematic diagram of the structure of a roller conveyor packaging mechanism according to an embodiment of this application is shown.
[0018] Figure 3 This is shown as a second schematic diagram of the structure of a drug dispensing device according to one embodiment of this application.
[0019] Figure 4 The third schematic diagram of the structure of the drug dispensing equipment in one embodiment of this application is shown.
[0020] Figure 5 The fourth schematic diagram of the structure of a drug dispensing device according to one embodiment of this application is shown.
[0021] Figure 6 The fifth schematic diagram of the structure of a drug dispensing device according to an embodiment of this application is shown.
[0022] Icon labels:
[0023] 100. Dispensing assembly; 101. Raw material rack; 102. Raw material container; 103. First metering device; 104. Dispensing rack; 105. Dispensing container; 106. Second metering device; 107. Electric suction pump; 108. Second valve; 109. Third valve; 110. Fourth valve; 111. Fifth valve; 112. First flow meter; 113. Second flow meter; 114. Third flow meter; 115. Shielding enclosure; 116. First dispensing pipeline; 117. Second dispensing pipeline;
[0024] 200. Dilution assembly; 201. Diluent rack; 202. Diluent container; 203. Third measuring instrument; 204. Dilution piping; 205. First valve;
[0025] 300. Controller; 301. Interactive screen;
[0026] 400. Extraction component; 401. Syringe; 402. Push-pull mechanism. Detailed Implementation
[0027] To make the above-mentioned objectives, features, and advantages of this application more apparent and understandable, the specific embodiments of this application are described in detail below with reference to the accompanying drawings. Many specific details are set forth in the following description to provide a thorough understanding of this application. However, this application can be implemented in many other ways different from those described herein, and those skilled in the art can make similar modifications without departing from the spirit of this application. Therefore, this application is not limited to the specific embodiments disclosed below.
[0028] In the description of this application, it should be understood that if terms such as "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", "axial", "radial", "circumferential" appear, these terms indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings, and are only for the convenience of describing this application and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this application.
[0029] Furthermore, where the terms "first" and "second" appear, these terms are for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of technical features indicated. Thus, a feature defined with "first" or "second" may explicitly or implicitly include at least one of that feature. In the description of this application, where the term "multiple" appears, "multiple" means at least two, such as two, three, etc., unless otherwise explicitly specified.
[0030] In this application, unless otherwise expressly specified and limited, the terms "installation," "connection," "joining," and "fixing," etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components, unless otherwise expressly limited. Those skilled in the art can understand the specific meaning of the above terms in this application based on the specific circumstances.
[0031] In this application, unless otherwise expressly specified and limited, the use of descriptions such as "above" or "below" the second feature indicates that the first and second features are in direct contact or indirect contact via an intermediate medium. Furthermore, "above," "on top of," and "over" the second feature can mean that the first feature is directly above or diagonally above the second feature, or simply that the first feature is at a higher horizontal level than the second feature. Similarly, "below," "below," and "under" the second feature can mean that the first feature is directly below or diagonally below the second feature, or simply that the first feature is at a lower horizontal level than the second feature.
[0032] It should be noted that if an element is referred to as being "fixed to" or "set on" another element, it can be directly on the other element or there may be an intervening element. If an element is considered to be "connected to" another element, it can be directly connected to the other element or there may be an intervening element. If so, the terms "vertical," "horizontal," "upper," "lower," "left," "right," and similar expressions used in this application are for illustrative purposes only and do not represent the only possible implementation.
[0033] See Figure 1 , Figure 1This image shows a schematic diagram of a drug dispensing device according to one embodiment of this application. The drug dispensing device provided in this embodiment includes a dispensing component 100, a dilution component 200, and a controller 300. The dispensing component 100 is disposed within a shielding cavity 115. The dispensing component 100 includes a stock solution holder 101, a first metering device 103, a dispensing rack 104, a second metering device 106, and an electric suction pump 107. The first metering device 103 measures the amount of liquid in the stock solution container 102 placed in the stock solution holder 101. The second metering device 106 measures the amount of liquid in the dispensing container 105 placed in the dispensing rack 104. The electric suction pump 107 is capable of dispensing the stock solution into the dispensing container 105. The stock solution in liquid container 102 is extracted and dispensed into dispensing container 105; the dilution assembly 200 includes a dilution rack 201, a third metering device 203, a dilution pipeline 204, and a first valve 205. The third metering device 203 is used to measure the amount of liquid in the dilution container 202 placed in the dilution rack 201. The first end of the dilution pipeline 204 can communicate with the opening of the dilution container 202 provided in the dilution rack 201, and the second end of the dilution pipeline 204 is connected to the dispensing assembly 100. The first valve 205 is installed on the dilution pipeline 204; the controller 300 is communicatively connected to the dispensing assembly 100 and the dilution assembly 200 respectively.
[0034] Specifically, the shielding body 115 may be made of a material with high shielding performance against radiopharmaceuticals to reduce the radiation hazards to other organisms. The shielding body 115 may be equipped with a switch door. When the switch door is open, the original liquid container 102 can be placed in the original liquid rack 101 or removed. The dispensing container 105 can also be placed in the dispensing rack 104 or removed. When the switch door is closed, it effectively shields the internal radiopharmaceuticals from external radiation. The shielding body 115 may be made of lead, for example. Lead is widely used for shielding radioactive objects due to its high density and good X-ray and gamma-ray shielding capabilities.
[0035] The first measuring device 103, the second measuring device 106, and the third measuring device 203 can be, for example, high-precision weighing platforms. The first measuring device 103 can be installed on the raw liquid rack 101 to weigh the raw liquid container 102 placed on the rack. Alternatively, the first measuring device 103 can be integrated with the raw liquid rack 101, in which case the rack can both hold and weigh the raw liquid container 102. The second measuring device 106 can be installed on the dispensing rack 104 to weigh the dispensing container 105 placed on the rack. Again, the second measuring device 106 can be integrated with the raw liquid rack 101, in which case the rack can both hold and weigh the dispensing container 105. The third measuring device 203 can be installed on the diluent rack 201 to weigh the diluent container 202 placed on the diluent rack 201. Alternatively, the third measuring device 203 can be integrated with the diluent rack 201, in which case the diluent rack 201 can both hold the diluent container 202 and measure its weight. Through the measuring device, the increase or decrease in liquid volume in the original liquid container 102, the dispensing container 105, and the diluent container 202 can be determined more accurately, thus enabling more precise dispensing of the original liquid from the original liquid container 102.
[0036] It should be noted that the above description of the shield 115 and the meter is merely exemplary. The types of shield 115 and meter protected by this application are not limited to those listed above. Those skilled in the art can set up and plan the shield 115 and meter according to the actual situation, as long as the technical principles of this application can be realized.
[0037] The dilution assembly 200 is provided with a dilution pipeline 204 and a first valve 205. When the first valve 205 is open, the liquid in the diluent container 202 can flow out of the dilution assembly 200 through the dilution pipeline 204 and flow to the dispensing assembly 100 to achieve dilution of the liquid in the original liquid container 102 and / or the liquid in the dispensing container 105.
[0038] The controller 300 can communicate with both the dispensing assembly 100 and the dilution assembly 200. For example, by communicating with the dispensing assembly 100, the controller 300 can control the opening and closing of the electric suction pump 107 and its suction power within the dispensing assembly 100. By communicating with the dilution assembly 200, the controller 300 can control the opening and closing of the first valve 205 within the dilution assembly 200. Through its communication with both the dispensing assembly 100 and the dilution assembly 200, the controller 300 can also acquire metering data from the first metering device 103, the second metering device 106, and the third metering device 203.
[0039] The aforementioned drug dispensing equipment, through the cooperation of the dispensing component 100, the dilution component 200, and the controller 300, can automatically package the raw liquid placed into the drug dispensing equipment without manual intervention, greatly saving dispensing time. Furthermore, the dispensing component 100 and the dilution component 200 include a first metering device 103 for measuring the liquid volume in the raw liquid container 102, a second metering device 106 for measuring the liquid volume in the dispensing container 105, and a third metering device 203 for measuring the liquid volume in the diluent container 202, thus achieving precise packaging of the raw liquid. Moreover, the dispensing component 100 in this device is located within the shielding chamber 115, which effectively reduces the risk of radiation exposure to personnel from the radioactive raw liquid and allows for dispensing in any location, eliminating the need for a fixed location.
[0040] Furthermore, the dispensing assembly 100 may also include a first shaker and a second shaker, wherein the first shaker is capable of shaking the stock solution container 102 placed on the stock solution rack 101, and the second shaker is capable of shaking the dispensing container 105 placed on the dispensing rack 104; the controller 300 is communicatively connected to the first shaker and the second shaker respectively.
[0041] It is understandable that prolonged storage of drugs may lead to drug precipitation, resulting in uneven drug distribution within the container, such as lower drug density at the top and higher drug density at the bottom. In such cases, direct drug dispensing would affect the accuracy of the dispensing. Therefore, the dispensing assembly 100 may further include a first shaker and a second shaker. The first shaker agitates the stock solution container 102 placed on the stock solution rack 101 to make the liquid in the stock solution container 102 more uniform. The second shaker agitates the dispensing container 105 placed on the dispensing rack 104 to make the liquid in the dispensing container 105 more uniform. The first shaker may be integrated with the stock solution rack 101, and the second shaker may be integrated with the dispensing rack 104. The shaker can be, for example, a vibrator or a rotary driver. For instance, the first shaker can be connected to the original liquid rack 101, which can drive the original liquid rack 101 to vibrate or rotate for mixing. The second shaker can be connected to the dispensing rack 104, which can drive the dispensing rack 104 to vibrate or rotate for mixing.
[0042] When the dispensing assembly 100 includes a first shaker and a second shaker, the controller 300 can be communicatively connected to the first shaker and the second shaker respectively, and thus the controller 300 can control the start and stop of the first shaker and the second shaker.
[0043] The first shaker described above can be used to shake the liquid in the original liquid container 102 before dispensing it, so as to make the dispensing uniform and improve the dispensing accuracy. The second shaker described above can be used to shake the liquid in the dispensing container 105 before it is used, so as to obtain a liquid of appropriate density from the dispensing container 105.
[0044] For example, the packaging rack 104 may be a packaging and transfer mechanism including multiple compartments, each compartment being used to place a packaging container 105, and the packaging and transfer mechanism is capable of changing the position of the packaging container 105; the controller 300 is communicatively connected to the packaging and transfer mechanism.
[0045] Understandably, to improve drug dispensing efficiency, multiple compartments for placing dispensing containers 105 can be provided on the dispensing rack 104. Each compartment can hold one dispensing container 105, and the number of compartments can be, for example, 6, 7, 8, or 10, etc., without specific limitation in this embodiment. Furthermore, to achieve the moving dispensing of multiple dispensing containers 105, the dispensing rack 104 can be a dispensing transfer mechanism with multiple compartments, through which the position of the dispensing containers 105 can be changed. With this configuration, after one dispensing container 105 has been dispensed, its position can be adjusted to dispense the next dispensing container 105 to be dispensed, until all dispensing containers 105 have been dispensed.
[0046] When the dispensing component 100 is a dispensing and conveying mechanism that includes multiple compartments, the controller 300 can communicate with the dispensing and conveying mechanism, and thus control the start and stop of the dispensing and conveying mechanism to adjust the position of the dispensing container 105.
[0047] For example, the dispensing and conveying mechanism may include a turntable dispensing mechanism or a roller conveyor dispensing mechanism. Wherein, as... Figure 1 As shown, the turntable dispensing mechanism may include a rotating unit and a multi-compartment turntable. The rotating unit can drive the multi-compartment turntable to rotate, thereby changing the position of the compartments and thus changing the position of the dispensing containers 105 placed in the compartments. The rotating unit may be, for example, a drive motor. The dispensing and conveying mechanism may also include a roller conveyor dispensing mechanism. Figure 2 A schematic diagram of the roller conveyor packaging mechanism in one embodiment of this application is shown, as follows: Figure 2As shown, the roller conveyor packaging mechanism includes a roller conveyor consisting of a series of rollers, bearings and support structures, and a roller conveyor drive unit. Multiple packaging containers 105 can be set on the roller conveyor along the conveying direction of the roller conveyor. The rollers can be driven to rotate by the drive unit. Based on the rolling action of the rollers, the packaging containers 105 can be conveyed through the roller conveyor, and the position of the packaging containers 105 can be changed.
[0048] It should be noted that the above description of the packaging and transmission mechanism is merely exemplary. The types of packaging and transmission mechanisms protected by this application are not limited to those listed above. Those skilled in the art can set up and plan the packaging and transmission mechanism according to the actual situation, as long as it can realize the technical principles of this application.
[0049] The rotary dispensing mechanism or the roller conveyor dispensing mechanism is detachably installed within the cavity of the shield 115. It is understood that in some cases, the dispensed medication may be urgently needed. Therefore, the rotary dispensing mechanism or the roller conveyor dispensing mechanism can be detachably installed within the shield 115, so that when medication is urgently needed, such as after one or more bottles of medication have been dispensed, the rotary dispensing mechanism or the roller conveyor dispensing mechanism can be disassembled to retrieve the dispensed medication.
[0050] For example, the far end of the roller conveyor dispensing mechanism can also extend out of the shield 115, so that after dispensing a dispensing container 105 is completed, the dispensing container 105 can be moved to the far end of the roller conveyor dispensing mechanism to expose the shield 115, making it easy for medical personnel to take it out and use.
[0051] Furthermore, such as Figure 1As shown, the dispensing assembly 100 further includes a second valve 108, a third valve 109, a fourth valve 110, and a fifth valve 111; wherein, the first valve port 1 of the first valve 205 is connected to the opening of the diluent container 202 through the dilution pipeline 204, the second valve port 2 of the first valve 205 is connected to the first valve port 1 of the second valve 108, and the third valve port 3 of the first valve 205 is connected to the first valve port 1 of the fifth valve 111; the second valve port 2 of the second valve 108 is connected to the first valve port 1 of the third valve 109, the third valve port 3 of the second valve 108 is connected to the first port of the electric suction pump 107, and the second port of the electric suction pump 107 is connected to the fourth valve 111. The first port of valve 110 is connected; the second valve port 2 of the third valve 109 is connected to the second port of the fourth valve 110, the third valve port 3 of the third valve 109 is connected to the first end of the first liquid distribution pipeline 116, and the second end of the first liquid distribution pipeline 116 can be connected to the original liquid container 102; the third valve port 3 of the fourth valve 110 is connected to the second valve port 2 of the fifth valve 111, the third valve port 3 of the fifth valve 111 is connected to the first end of the second liquid distribution pipeline 117, and the second end of the second liquid distribution pipeline 117 can be connected to the dispensing container; the controller 300 is communicatively connected to the first valve 205, the second valve 108, the third valve 109, the fourth valve 110, and the fifth valve 111 respectively.
[0052] Among them, the first valve 205, the second valve 108, the third valve 109, the fourth valve 110, and the fifth valve 111 can be solenoid valves. The controller 300 can communicate with the first valve 205, the second valve 108, the third valve 109, the fourth valve 110, and the fifth valve 111, and can control the opening and closing of these valves. Through the above valve-to-valve connection, the liquid in the original liquid container 102 can be dispensed, and the dispensing pipeline can be cleaned. By cleaning the dispensing pipeline, the impact of residual liquid on the dispensing accuracy during subsequent dispensing processes can be reduced.
[0053] Furthermore, such as Figure 1 As shown, the dispensing assembly 100 further includes a first flow meter 112, a second flow meter 113, and a third flow meter 114; wherein, the first flow meter 112 is disposed on the first dispensing pipeline 116, the second flow meter 113 is disposed between the second port of the electric suction pump 107 and the first port of the fourth valve 110, and the third flow meter 114 is disposed between the third valve port 3 of the first valve 205 and the first valve port 1 of the fifth valve 111.
[0054] Specifically, by setting the first flow meter 112, the flow rate of liquid flowing into and out of the raw liquid container 102 can be measured; by setting the second flow meter 113, the flow rate of liquid flowing between the second port of the electric suction pump 107 and the first port of the fourth valve 110 can be measured; and by setting the third flow meter 114, the flow rate of liquid flowing between the third valve port 3 of the first valve 205 and the first valve port 1 of the fifth valve 111 can be measured.
[0055] Furthermore, by controlling the flow rate through the aforementioned first flow meter 112, second flow meter 113 and third flow meter 114, and combining this with the measurement of the first metering device 103, second metering device 106 and third metering device 203, the accuracy of dispensing can be further improved.
[0056] Below, in conjunction with Figures 1 to 6 The process of using this drug dispensing equipment for drug dispensing is illustrated by way of example.
[0057] When drug dispensing is required, the bulk solution container 102 containing the drug concentrate is first placed on the bulk solution rack 101. The controller 300 obtains and records the weight of the bulk solution container 102 measured by the first measuring device 103. Next, the controller 300 controls the first shaker to turn on to shake the liquid in the bulk solution container 102.
[0058] After shaking for a predetermined period of time, the controller 300 controls the first valve 205 to close, the second valve 108, the third valve 109, the fourth valve 110 and the fifth valve 111 to open, and controls the electric suction pump 107 to operate, so as to dispense the liquid in the original liquid container 102. Figure 3 This is shown as a second schematic diagram of the structure of a drug dispensing device according to one embodiment of this application. The flow path of the original liquid in the original liquid container 102 is as follows: Figure 3As indicated by the arrows, the stock solution in the stock solution container 102 is drawn out by the electric suction pump 107. The drawn-out stock solution flows into the third valve port 3 of the third valve 109, and after being diverted, flows out from the first valve port 1 and the second valve port 2 of the third valve 109. Furthermore, the stock solution flowing out from the first valve port 1 of the third valve 109 flows through the second valve port 2 and the third valve port 3 of the second valve 108, then flows into the pipeline where the electric suction pump 107 is located, and through the pipeline where the electric suction pump 107 is located, flows into the first valve port 1 of the fourth valve 110. The stock solution flowing in from the first valve port 1 and the second valve port 2 of the fourth valve 110 flows out through the third valve port 3 of the fourth valve 110 and then flows into the second valve port 2 of the fifth valve 111. The stock solution flowing in from the second valve port 2 of the fifth valve 111 flows into the dispensing container 105 through the third valve port 3 of the fifth valve 111. During the process of the original liquid being drawn out of the original liquid container 102, the controller 300 can control the flow rate and know the volume of liquid flowing into the dispensing bottle through the second flow meter 113. The second metering device 106 can measure the weight of the liquid in the dispensing container 105 and provide dynamic feedback to the controller 300. Based on the dynamic feedback of the second metering device 106, the controller 300 can dynamically adjust the switching quantity of the second flow meter 113 to achieve flow control and improve the dispensing accuracy of the original liquid in the dispensing container 105.
[0059] After the original solution is extracted, the controller 300 controls the first valve 205 and the fifth valve 111 to open, and the other valves to close. At this time, the diluent container 202 is connected to the dispensing container 105, and the diluent in the diluent container flows out to the dispensing container 105 to dilute the original solution in the dispensing container 105. Figure 4 The third schematic diagram shows the structure of a drug dispensing device according to one embodiment of this application. During this process, the flow path of the diluent is as follows: Figure 4 As shown by the arrows, the diluent flows into the first valve port 1 of the first valve 205 and out through the third valve port 3 of the first valve 205. The diluent flowing out through the third valve port 3 of the first valve 205 flows into the first valve port 1 of the fifth valve 111 and out through the third valve port 3 of the fifth valve 111, and then flows to the dispensing container 105 to achieve the purpose of diluting the original liquid in the dispensing container 105. During this dilution process, the flow rate of the diluent can be controlled by dynamic monitoring through the third flow meter 114 and the third metering device 203 to improve the dispensing accuracy of the diluent in the dispensing container 105.
[0060] After the above actions are completed, the controller 300 controls the first valve 205, the second valve 108 and the third valve 109 to open, and the other valves to close. The diluent container 202 is connected to the original liquid container 102, and the diluent in the diluent container 202 flows out to dilute the original liquid in the original liquid container 102. Figure 5 The fourth schematic diagram shows the structure of a drug dispensing device according to one embodiment of this application. The flow path of the diluent during this process is as follows: Figure 5 As shown by the arrows, the diluent flows into the first valve port 1 of the first valve 205 and out through the second valve port 2 of the first valve 205. The diluent flowing out through the second valve port 2 of the first valve 205 flows through the first valve port 1 and the second valve port 2 of the second valve 108 to the first valve port 1 of the third valve 109 and then into the original liquid container 102 through the third valve port 3 of the third valve 109. During this dilution process, the flow rate of the diluent can be controlled by dynamic monitoring through the first flow meter 112 and the first metering device 103, thereby improving the dilution accuracy of the diluent in the original liquid container 102.
[0061] After the above dispensing process, the pipeline can be cleaned. Specifically, the controller 300 controls the first valve 205, the second valve 108, the third valve 109 and the fourth valve 110 to open, while the other valves are closed, and connects the diluent container 202 to flush the pipeline and dilute the original liquid in the original liquid container 102. Figure 6 The fifth schematic diagram shows the structure of a drug dispensing device according to one embodiment of this application. The flow path of the diluent during this process is as follows: Figure 6 As indicated by the arrows, the diluent flows into the first valve port 1 of the first valve 205 and out through the second valve port 2 of the first valve 205. The diluent flowing out through the second valve port 2 of the first valve 205 then flows into the first valve port 1 of the second valve 108 and out through the second valve port 2 and the third valve port 3 of the second valve 108, respectively. The diluent flowing out through the third valve port 3 of the second valve 108 flows into the first valve port 1 of the fourth valve 110 and out through the second valve port 2 of the fourth valve 110. The diluent flowing out through the second valve port 2 of the second valve 108 flows into the first valve port 1 of the third valve 109 and out through the third valve port 3 of the third valve 109, flowing towards the original liquid container 102. During this process, the flow rate of the diluent can be controlled by the dynamic coordination of the first flow meter 112 and the first metering device 103, thereby improving the dilution accuracy of the diluent in the original liquid container 102.
[0062] After the pipeline flushing is completed, the controller 300 can calculate the volume in the original liquid container 102 based on the data from the first metering device 103, and then calculate the amount of diluent that needs to be added to the original liquid container 102. Then the controller 300 opens the first valve 205, the second valve 108 and the third valve 109 again, and closes the other valves to meet the dilution requirements of the original liquid in the original liquid container 102.
[0063] It is understandable that, when the dispensing rack 104 is a dispensing and transfer mechanism with multiple compartments, each dispensing container 105 can be filled sequentially according to the above order to meet the needs of different dosage dispensing. Specifically, the next dispensing container 105 will only be filled after the filling process of each dispensing container 105 is completed and the pipeline is flushed, until all the required dispensing containers 105 have been filled. After filling, each dispensing container 105 contains a pre-set specific volume of dispensing liquid.
[0064] Furthermore, the drug dispensing device may also include an extraction component 400, which includes a syringe 401 and a push-pull mechanism 402. The push-pull mechanism 402 is connected to the pushing end of the syringe 401, and the injection end of the syringe 401 is connected to the fourth valve port of the fifth valve 111. The controller 300 is communicatively connected to the push-pull mechanism 402.
[0065] Specifically, if an injection is required for a patient, medication needs to be drawn from syringe 401. To facilitate injection, the medication dispensing device may also include a receiving component. This extraction component 400 may include syringe 401 and a push-pull mechanism 402. The push-pull mechanism 402 is connected to the pushing end of syringe 401, and the injection end of syringe 401 is connected to the fourth port of fifth valve 111. Thus, when fifth valve 111 is opened, and the fourth port and third port 3 of fifth valve 111 are connected, the push-pull mechanism 402 pulls the pushing end of syringe 401, allowing syringe 401 to extract the dispensed liquid from dispensing container 105. Controller 300 can communicate with push-pull mechanism 402 to control its pushing and pulling action. During extraction, second meter 106 can detect the weight in real time and provide feedback to controller 300 to ensure no residue remains in dispensing container 105. The push-pull mechanism 402 can be, for example, an electric actuator, which is a common push-pull mechanical structure. It uses a motor to drive a gearbox (such as a parallel shaft gearbox or a worm gear gearbox) to drive a lead screw, which in turn causes the nut to move the push rod sleeve forward or backward.
[0066] The dilution assembly 200 further includes a third shaker, which is capable of shaking the dilution container 202 placed on the dilution rack 201.
[0067] It is understandable that prolonged storage of the diluent may lead to sedimentation, resulting in uneven distribution of the diluent within the container, such as a lower density at the top and a higher density at the bottom. Therefore, the dilution assembly 200 may further include a third shaker, which agitates the diluent container 202 placed on the diluent rack 201 to ensure a more uniform distribution of the diluent within the container 202. The third shaker may be integrated with the diluent rack 201.
[0068] For example, the controller 300 includes an interactive screen 301. Through this interactive screen, medical personnel or equipment operators can set up dispensing operations. The interactive screen 301 can also provide feedback to medical personnel or equipment operators, improving the level of automation and intelligence.
[0069] The technical features of the above embodiments can be combined in any way. For the sake of brevity, not all possible combinations of the technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.
[0070] The embodiments described above are merely illustrative of several implementation methods of this application, and while the descriptions are relatively specific and detailed, they should not be construed as limiting the scope of the patent application. It should be noted that those skilled in the art can make various modifications and improvements without departing from the concept of this application, and these all fall within the protection scope of this application. Therefore, the protection scope of this patent application should be determined by the appended claims.
Claims
1. A drug dispensing device, characterized in that, include: Dispensing component (100), dilution component (200), and controller (300); The dispensing assembly (100) is disposed inside the cavity of the shield (115). The dispensing assembly (100) includes a raw liquid rack (101), a first metering device (103), a dispensing rack (104), a second metering device (106), and an electric suction pump (107). The first metering device (103) is used to measure the amount of liquid in the raw liquid container (102) placed on the raw liquid rack (101). The second metering device (106) is used to measure the amount of liquid in the dispensing container (105) placed on the dispensing rack (104). The electric suction pump (107) can extract the raw liquid in the raw liquid container (102) and dispense it into the dispensing container (105). The dilution assembly (200) includes a diluent rack (201), a third meter (203), a dilution line (204), and a first valve (205). The third meter (203) is used to measure the amount of liquid in the diluent container (202) placed on the diluent rack (201). The first end of the dilution line (204) is connected to the opening of the diluent container (202) on the diluent rack (201), and the second end of the dilution line (204) is connected to the dispensing assembly (100). The first valve (205) is installed on the dilution line (204). The controller (300) is communicatively connected to the dispensing component (100) and the dilution component (200), respectively.
2. The drug dispensing equipment according to claim 1, characterized in that, The dispensing assembly (100) further includes a first shaker and a second shaker, wherein the first shaker is capable of shaking the original liquid container (102) placed on the original liquid rack (101), and the second shaker is capable of shaking the dispensing container (105) placed on the dispensing rack (104). The controller (300) is communicatively connected to the first shaker and the second shaker, respectively.
3. The drug dispensing equipment according to claim 1, characterized in that, The dispensing rack (104) can be a dispensing and conveying mechanism including multiple compartments, each compartment being used to place a dispensing container (105), and the dispensing and conveying mechanism is capable of changing the position of the dispensing container (105). The controller (300) is communicatively connected to the dispensing and transmission mechanism.
4. The drug dispensing equipment according to claim 3, characterized in that, The packaging and conveying mechanism includes a turntable packaging mechanism or a roller conveyor packaging mechanism.
5. The drug dispensing equipment according to claim 4, characterized in that, The turntable dispensing mechanism or the roller conveyor dispensing mechanism is detachably installed inside the cavity of the shield (115).
6. The drug dispensing equipment according to claim 1, characterized in that, The sub-assembly assembly (100) further includes a second valve (108), a third valve (109), a fourth valve (110), and a fifth valve (111); wherein, The first valve port of the first valve (205) can be connected to the opening of the diluent container (202) through the dilution pipeline (204), the second valve port of the first valve (205) is connected to the first valve port of the second valve (108), and the third valve port of the first valve (205) is connected to the first valve port of the fifth valve (111). The second valve port of the second valve (108) is connected to the first valve port of the third valve (109), the third valve port of the second valve (108) is connected to the first port of the electric suction pump (107), and the second port of the electric suction pump (107) is connected to the first port of the fourth valve (110). The second valve port of the third valve (109) is connected to the second port of the fourth valve (110). The third valve port of the third valve (109) is connected to the first end of the first liquid distribution pipeline (116). The second end of the first liquid distribution pipeline (116) can be connected to the original liquid container (102). The third valve port of the fourth valve (110) is connected to the second valve port of the fifth valve (111). The third valve port of the fifth valve (111) is connected to the first end of the second liquid distribution pipeline (117). The second end of the second liquid distribution pipeline (117) can be connected to the dispensing container (105). The controller (300) is communicatively connected to the first valve (205), the second valve (108), the third valve (109), the fourth valve (110), and the fifth valve (111), respectively.
7. The drug dispensing equipment according to claim 6, characterized in that, The dispensing assembly (100) further includes a first flow meter (112), a second flow meter (113), and a third flow meter (114); wherein the first flow meter (112) is disposed on the first dispensing pipeline (116), the second flow meter (113) is disposed between the second port of the electric suction pump (107) and the first port of the fourth valve (110), and the third flow meter (114) is disposed between the third valve port of the first valve (205) and the first valve port of the fifth valve (111).
8. The drug dispensing equipment according to claim 6, characterized in that, It also includes an extraction component (400), which includes a syringe (401) and a push-pull mechanism (402). The push-pull mechanism (402) is connected to the push end of the syringe (401), and the injection end of the syringe (401) is connected to the fourth valve port of the fifth valve (111). The controller (300) is communicatively connected to the push-pull mechanism (402).
9. The drug dispensing equipment according to any one of claims 1-8, characterized in that, The dilution assembly (200) also includes a third shaker that enables the dilution container (202) placed on the dilution rack (201) to be shaken.
10. The drug dispensing equipment according to any one of claims 1-8, characterized in that, The controller (300) includes an interactive screen (301).