Private care wet tissue containing antibacterial composition and preparation method of private care wet tissue

Abstract

The invention discloses a private care wet tissue containing a bacteriostatic composition, the private care wet tissue comprises a composite non-woven fabric base material and an impregnation liquid, the impregnation liquid comprises the bacteriostatic composition, a soothing anti-inflammatory agent, a moisturizing repairing agent, an odor removal regulator, a cosolvent and a stabilizer; the preparation method comprises the following steps: adding purified water, a citric acid-sodium citrate buffer agent and EDTA (Ethylene Diamine Tetraacetic Acid) disodium into a vacuum stirring tank, then adding glycerol, micromolecular sodium hyaluronate and ceramide 3, and then adding L-lactic acid and a lactobacillus acidophilus fermentation product; sequentially adding nisin, cranberry extract, polyhexamethylene biguanide hydrochloride and beta-cyclodextrin inclusion tea tree essential oil, and finally adding dipotassium glycyrrhizinate, allantoin and citrus extract. Different from the prior art that private care wet tissues only have a single antibacterial function and neglect flora balance, peculiar smell is covered by depending on essence, the base material and the steeping liquor are designed at the same time, and the functions of bacteriostasis and antibiosis, gentle private care, odor removal and itching relieving, inflammation prevention and swelling prevention, flora balance maintenance and the like are achieved.

Description

Technical Field

[0001] This invention belongs to the field of feminine hygiene and relates to a feminine hygiene wipe containing an antibacterial composition and its preparation method. Background Technology

[0002] With the improvement of living standards, people have new demands for health and convenience, leading to the emergence of feminine hygiene wipes. Currently, the feminine hygiene wipe market is experiencing a period of rapid growth coupled with a regulatory transition. Many manufacturers produce feminine hygiene wipes, but companies need to truly balance antibacterial effects, safety, and cost, focusing on real consumer needs to stand out in the fierce competition.

[0003] The research and development of feminine hygiene wipes technology is difficult and costly, and there are compliance risks such as the addition of prohibited substances, strict filing requirements, severe market competition, and fierce price wars.

[0004] Therefore, there is an urgent need for a differentiated feminine hygiene wipe product that is safe in ingredients, has a targeted formula, is low in irritation, does not damage beneficial bacteria, and is environmentally friendly and biodegradable. Summary of the Invention

[0005] The purpose of this invention is to address the shortcomings of existing technologies and propose a feminine hygiene wipe that differs from existing technologies. This feminine hygiene wipe is designed with both a base material and an impregnation liquid, achieving functions such as antibacterial and antimicrobial properties, gentle vaginal care, deodorization and itch relief, anti-inflammatory and anti-redness, and maintenance of flora balance.

[0006] To achieve the above objectives, the present invention adopts the following technical solution: a feminine hygiene wipe containing an antibacterial composition, wherein the feminine hygiene wipe containing the antibacterial composition comprises a composite nonwoven fabric substrate and an impregnation liquid, wherein the impregnation liquid comprises: an antibacterial composition, a soothing and anti-inflammatory agent, a moisturizing and repairing agent, an odor-regulating agent, a solubilizer, and a stabilizer. The feminine wipes containing the antibacterial composition, calculated by weight, include the following components: 0.01-0.03 parts of nisin, 0.1-0.3 parts of cranberry extract, 0.02-0.05 parts of polyhexamethylene biguanide hydrochloride, and 0.05-0.10 parts of β-cyclodextrin-encapsulated tea tree oil; 0.1-0.25 parts of dipotassium glycyrrhizate and 0.05-0.15 parts of allantoin; 0.03-0.08 parts of sodium hyaluronate and 0.02-0.06 parts of ceramide 3; 0.1-0.3 parts of citrus extract and 0.1-0.3 parts of citric acid-sodium citrate buffer; and 1.0-2.0 parts of glycerin and 0.01-0.03 parts of disodium EDTA.

[0007] As a further description of the above technical solution: the feminine wipes containing the antibacterial composition also contain 0.2 to 0.5 parts of L-lactic acid and 0.5 to 1.0 parts of Lactobacillus acidophilus fermentation product.

[0008] As a further description of the above technical solution: the feminine wipes containing the antibacterial composition also contain a preservative, wherein the preservative is methylparaben, and the content is 0.05~0.1 parts.

[0009] As a further description of the above technical solution: the feminine wipes containing the antibacterial composition, calculated by weight, include 0.02 parts of nisin, 0.2 parts of cranberry extract, 0.03 parts of polyhexamethylene biguanide hydrochloride, and 0.08 parts of β-cyclodextrin-encapsulated tea tree oil; the soothing and anti-inflammatory agent is 0.2 parts of dipotassium glycyrrhizate and 0.1 parts of allantoin; the moisturizing and repairing agent is 0.05 parts of small molecule sodium hyaluronate and 0.04 parts of ceramide 3; the deodorizing agent includes 0.2 parts of citrus extract and 0.2 parts of citric acid-sodium citrate buffer; the solubilizer and stabilizer are 1.5 parts of glycerin, 0.02 parts of disodium EDTA, 0.35 parts of L-lactic acid, 0.8 parts of Lactobacillus acidophilus fermentation product, and 0.08 parts of methylparaben, with the remainder being purified water.

[0010] As a further description of the above technical solution: the impregnation ratio of the impregnation liquid to the substrate is 1:3 to 1:5.

[0011] As a further description of the above technical solution: the impregnation ratio of the impregnation liquid to the substrate is 1:4.

[0012] A method for manufacturing feminine wipes containing an antibacterial composition, wherein the preparation step of the impregnation solution is as follows: Step 1: Add 80 parts of purified water to a vacuum mixing tank, heat to 40°C, add citric acid-sodium citrate buffer and disodium EDTA, stir at 200 r / min for 10 min until completely dissolved; Step 2: Keep the temperature at 40℃, add glycerol, sodium hyaluronate (small molecule), and ceramide 3 in sequence, increase the stirring speed to 300r / min, and stir for 20min; Step 3: Reduce the stirring speed to 150 r / min, add L-lactic acid and Lactobacillus acidophilus fermentation products, stir for 15 min, and keep the temperature below 45℃; Step 4: Keep the temperature at 35~40℃, add nisin, cranberry extract, polyhexamethylene biguanide hydrochloride, and β-cyclodextrin-encapsulated tea tree oil in sequence, stir at 200r / min for 30min; Step 5: Add dipotassium glycyrrhizate, allantoin, and citrus extract, and stir for 15 minutes until the system is uniform and transparent; Step 6: Adjust the pH of the system to 3.8-4.5 using a 0.1 mol / L lactic acid or sodium hydroxide solution; Add the remaining 20 parts of purified water to a final volume of 100 parts, and continue stirring for 10 minutes; Step 7: Turn off the stirring and let it stand for 20 minutes to remove air bubbles.

[0013] As a further description of the above technical solution: In step four, the time interval between the addition of nisin and polyhexamethylene biguanide hydrochloride is 5 minutes.

[0014] Due to the adoption of the above technical solution, the beneficial effects achieved by this invention are: (1) This invention employs compound antibacterial agents, combining natural antibacterial components with mild synthetic antibacterial agents, which can enhance antibacterial efficacy and reduce irritation; (2) In the microbial community regulation of the present invention, the method of adding prebiotics and probiotic fermentation products is adopted, which changes the method of killing harmful bacteria in the prior art to regulating the growth of beneficial bacteria in the formula of the present invention; (3) The substrate provided by the present invention is functionalized and modified. The chitosan fiber composite substrate has antibacterial properties and can reduce the dependence on impregnation solution. (4) This invention can remove odors at the source and soothe and reduce inflammation. It decomposes odor molecules and, when combined with barrier repair ingredients, can relieve itching, reduce inflammation and prevent redness and swelling. Detailed Implementation

[0015] The technical solutions in the embodiments of the present invention will be clearly and completely described below. Obviously, the described embodiments are only a part of the embodiments of the present invention, and not all of them. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0016] The present invention will be described in detail with reference to the following embodiments: Example 1

[0017] This embodiment provides a feminine hygiene wipe containing an antibacterial composition, the feminine hygiene wipe containing the antibacterial composition comprising a composite nonwoven fabric substrate and an impregnation liquid.

[0018] Part 1: The substrate is a composite nonwoven fabric, specifically containing the following components, calculated by weight: 55-65 parts viscose fiber, 20-30 parts chitosan fiber, and 10-20 parts polyester staple fiber (food grade).

[0019] Part Two: The impregnation solution includes: an antibacterial composition, a soothing and anti-inflammatory agent, a moisturizing and repairing agent, a deodorizing agent, a solubilizer, and a stabilizer. The feminine hygiene wipes containing the antibacterial composition are calculated in parts by weight. The antibacterial composition includes Nisin 0.01~0.03 parts Cranberry extract 0.1~0.3 parts Polyhexamethylene biguanide hydrochloride 0.02~0.05 parts 0.05-0.10 parts of tea tree oil were encapsulated with β-cyclodextrin. The soothing and anti-inflammatory agent is Dipotassium glycyrrhizate 0.1~0.25 parts Allantoin 0.05~0.15 parts; The moisturizing and repairing agent is Small molecule sodium hyaluronate 0.03~0.08 parts Ceramide 3, 0.02~0.06 parts; Odor regulators include Citrus extract 0.1~0.3 parts Citric acid-sodium citrate buffer: 0.1-0.3 parts; The cosolvent and stabilizer are: Glycerin 1.0~2.0 parts 0.01~0.03 parts of disodium EDTA; The feminine wipes containing the antibacterial composition also contain: Lactic acid 0.2~0.5 parts 0.5-1.0 parts of Lactobacillus acidophilus fermentation product; The preservative is methylparaben, with a content of 0.05~0.1 parts.

[0020] The formula provided by this invention differs from existing wet wipes in that it focuses on single antibacterial properties, ignores the balance of the microbial community, and relies on fragrances to mask odors. It adopts a manufacturing method that inhibits bacteria without killing them, protects the microbial community without disturbing it, and soothes without irritation. It simultaneously achieves functions such as antibacterial and antimicrobial properties, gentle vaginal care, deodorization and itch relief, anti-inflammatory and anti-redness, and maintenance of the microbial community balance, providing women with special protection. Example 2

[0021] This embodiment provides an optimal formulation for feminine hygiene wipes containing an antibacterial composition. The antibacterial composition, calculated by weight, comprises: 0.02 parts nisin, 0.2 parts cranberry extract, 0.03 parts polyhexamethylene biguanide hydrochloride, and 0.08 parts β-cyclodextrin-encapsulated tea tree oil; 0.2 parts dipotassium glycyrrhizate and 0.1 parts allantoin as the soothing and anti-inflammatory agents; 0.05 parts sodium hyaluronate and 0.04 parts ceramide 3 as the moisturizing and repairing agents; 0.2 parts citrus extract and 0.2 parts citric acid-sodium citrate buffer as the deodorizing agents; 1.5 parts glycerin, 0.02 parts disodium EDTA, 0.35 parts L-lactic acid, 0.8 parts Lactobacillus acidophilus fermentation product, and 0.08 parts methylparaben; the remainder is purified water.

[0022] In this embodiment, the substrate is still a composite nonwoven fabric, which specifically contains the following components, calculated by weight: 60 parts viscose fiber, 25 parts chitosan fiber, and 15 parts polyester staple fiber (food grade). The specific components are shown in Table 1 below.

[0023] .

[0024] The viscose fiber, comprising 60 parts, serves as the main substrate, providing excellent absorbency and softness, conforming to the vulvar skin without friction. Unlike the rough texture of existing polyester nonwoven fabrics, the skin-friendly nature of viscose fiber reduces the risk of vulvar skin friction and redness. The viscose fiber in this invention can quickly absorb secretions and impregnation fluids, leaving no sticky feeling during use.

[0025] Existing wet wipe substrates only serve as a carrier for wet wipes and lack functionality. This formulation, through modification with chitosan fibers, achieves dual antibacterial properties in both the substrate and the impregnation solution, reducing reliance on chemical additives. In this embodiment, 25 parts of chitosan fibers are used. Since chitosan is a natural cationic polysaccharide with inherent antibacterial activity and is biodegradable, the design of 25 parts of chitosan fibers achieves the following beneficial effects: First, it inhibits harmful bacteria such as Escherichia coli and Staphylococcus aureus, reducing the amount of antibacterial agent used in the impregnation solution; Secondly, it promotes the repair of skin and mucous membranes and reduces irritation; Secondly, improve the moisture absorption and breathability of the substrate.

[0026] In this embodiment, 15 parts of polyester staple fiber are used, which can significantly improve the tensile strength of the substrate and prevent the wipes from breaking during use; at the same time, it ensures the toughness of the wipes and prevents them from shedding lint during wiping.

[0027] The antibacterial composition in this embodiment includes 0.02 parts of nisin, 0.2 parts of cranberry extract, 0.03 parts of polyhexamethylene biguanide hydrochloride, and 0.08 parts of β-cyclodextrin-encapsulated tea tree oil.

[0028] Nisin is a natural peptide antibacterial agent that can inhibit Gram-positive bacteria, such as Staphylococcus aureus, without killing beneficial bacteria. At the same time, it targets and inhibits harmful bacteria without disrupting the vaginal flora. The antibacterial rate is ≥99% after 24 hours of testing. Compared with broad-spectrum bactericides, the addition of nisin can achieve targeted antibacterial action and avoid flora imbalance.

[0029] Cranberry extract is rich in proanthocyanidins, which can inhibit pathogenic bacteria from adhering to the mucous membrane of the reproductive tract, block the infection path, reduce the colonization of harmful bacteria from the root, and help prevent vulvitis. At the same time, it has antioxidant properties. Unlike the surface antibacterial properties of traditional plant extracts, it can achieve adhesion blocking and improve the antibacterial durability.

[0030] Polyhexamethylene biguanide hydrochloride (PHMB) is a low-concentration, mild synthetic antibacterial agent that synergistically enhances the effects of natural ingredients. It is effective against fungi, such as Candida albicans. The addition of PHMB can broaden the antibacterial spectrum, taking into account the inhibition of both bacteria and fungi. It is non-irritating when the concentration is ≤0.03%, but high concentrations ≥0.1% can easily cause mucosal irritation. In this invention, the concentration of PHMB is reduced to a safe range.

[0031] β-Cyclodextrin encapsulates tea tree oil, effectively reducing its irritation, achieving sustained-release antibacterial activity, and minimizing the irritation of tea tree oil to sensitive mucous membranes; it also prolongs the antibacterial time, with a sustained-release time of up to 8 hours in tests; and it provides a cooling and soothing effect, relieving itching.

[0032] The soothing and anti-inflammatory agents are 0.2 parts dipotassium glycyrrhizate and 0.1 parts allantoin. Dipotassium glycyrrhizate is a natural anti-inflammatory ingredient that can inhibit histamine release, relieve itching and redness, and quickly soothe itching and burning caused by vulvitis. It has no hormonal side effects, is gentle and safe, and is suitable for daily care. Allantoin can repair the skin and mucous membrane barrier, promote cell regeneration, repair damaged vulvar skin, reduce friction and redness, and relieve dryness and peeling. It fills the gap in existing feminine care wipes that focus on antibacterial properties but not on repair, and improves the safety of long-term use.

[0033] The moisturizing and repairing agent consists of 0.05 parts of low-molecule sodium hyaluronate and 0.04 parts of ceramide 3. The low-molecule hyaluronic acid provides deep hydration, while the ceramide repairs the skin barrier. The combination of the two can achieve the following functions: Keep the vulvar skin moisturized to prevent dryness and itching; It enhances the resistance of the mucous membrane and reduces inflammation caused by external stimuli.

[0034] The odor-regulating agent comprises 0.2 parts of citrus extract and 0.2 parts of citric acid-sodium citrate buffer. The citrus extract contains flavonoids, which can break down odor molecules such as ammonia and sulfides, rather than masking the odor. It can eliminate odor from the source, providing long-lasting freshness without fragrance irritation, making it suitable for sensitive skin. The citric acid-sodium citrate buffer stabilizes the pH of the impregnation solution at 3.8-4.5, matching the natural slightly acidic environment of the intimate area and preventing pH fluctuations from disrupting the flora; it also enhances formula stability and extends shelf life. Existing buffering systems are mostly single acids with poor pH stability; the citric acid-sodium citrate buffer provided by this invention has a stronger buffering capacity and better meets physiological needs.

[0035] Glycerin enhances the solubility of ingredients and prevents wipes from drying and hardening. Disodium EDTA chelates metal ions, preventing the formula from oxidizing and deteriorating, and improving stability. Methylparaben is a low-concentration, mild preservative that inhibits the growth of microorganisms in the formula. At a concentration of ≤0.08%, it does not cause mucosal irritation, unlike the irritation of existing high-concentration preservatives.

[0036] The feminine hygiene wipes containing an antibacterial composition described in this invention can achieve the following beneficial effects: (1) Antibacterial and antimicrobial properties: The antibacterial rate against Escherichia coli, Staphylococcus aureus and Candida albicans is ≥99%, and the antibacterial effect lasts for more than 8 hours.

[0037] (2) No irritation reaction such as erythema or edema was observed after skin irritation test.

[0038] (3) Removes odor, relieves itching, inhibits bacteria at the source, relieves itching within 5 minutes after use, and has an odor elimination rate of ≥95%.

[0039] (4) Maintaining the balance of the flora: After use, the number of lactobacilli in the private parts increases by more than 30%, and the flora structure tends to be healthier.

[0040] (5) The weakly acidic environment and the mucosal repair components protect the reproductive tract, reduce the adhesion of pathogenic bacteria, and reduce the risk of recurrence of vulvitis and vaginitis. Example 3

[0041] In Example 2, the addition of 0.02 parts of nisin and 0.03 parts of polyhexamethylene biguanide hydrochloride to a feminine hygiene wipe containing an antibacterial composition not only utilizes the natural targeting of nisin to protect beneficial bacteria, but also covers the antibacterial blind spot of nisin with a low concentration of polyhexamethylene biguanide hydrochloride. At the same time, it significantly reduces the concentration of polyhexamethylene biguanide hydrochloride used, which is far below the irritation threshold of 0.1%, thus achieving the goal of strong antibacterial effect, no irritation, and protection of bacterial flora.

[0042] Regarding the selection of ingredients, the absolute contraindication of nisin is a concentration greater than 0.05 parts, and it cannot be used alone at high concentrations. It is only used for targeted antibacterial purposes. Therefore, in this invention, the concentration of nisin is set within the safe and effective concentration range, specifically within 0.01 to 0.03 parts.

[0043] Because the concentration of polyhexamethylene biguanide hydrochloride is positively correlated with its irritant properties, it must be compounded at low concentrations. The absolute contraindication concentration is greater than 0.1 parts. Therefore, in this invention, the concentration of polyhexamethylene biguanide hydrochloride is set within the safe and effective concentration range of 0.02 to 0.05 parts. Example 4

[0044] A process for preparing feminine wipes containing an antibacterial composition includes the preparation of a composite nonwoven fabric and the preparation of an impregnation solution. This embodiment provides an overall description of the preparation of the composite nonwoven fabric and the preparation of the impregnation solution to better produce feminine wipes containing an antibacterial composition.

[0045] 1. Preparation of composite nonwoven fabric: Viscose fiber, chitosan fiber, and polyester staple fiber are mixed and combed, hydroentangled, dried, and then cut into wet wipe specifications.

[0046] II. Preparation of Impregnation Solution: Step 1: Heat purified water to 40°C, add buffer system and disodium EDTA, and stir to dissolve; Step 2: Add glycerin, sodium hyaluronate, and ceramide 3 in sequence, and stir until completely dissolved; Step 3: Add the antibacterial composition, microbial balancing ingredients, and soothing ingredients, and stir at low speed for 30 minutes; Step 4: Add preservatives, adjust pH to 3.8-4.5, and let stand to remove bubbles.

[0047] 3. Impregnation and cutting: Immerse the composite nonwoven fabric in the impregnation solution with a liquid-to-material ratio of 1:4, vacuum impregnate for 10 minutes, remove and drain excess liquid, seal and package, and finally perform irradiation sterilization. Example 5

[0048] This embodiment provides a preparation process for feminine hygiene wipes containing an antibacterial composition, used to produce the aforementioned feminine hygiene wipes containing the antibacterial composition, wherein... The steps for preparing the impregnation solution are as follows: Step 1: Add 80 parts of purified water to a vacuum mixing tank, heat to 40°C, add citric acid-sodium citrate buffer and disodium EDTA, stir at 200 r / min for 10 min until completely dissolved; Step 2: Maintain the temperature at 40℃, add glycerol, sodium hyaluronate (small molecule), and ceramide 3 in sequence, increase the stirring speed to 300r / min, and stir for 20min; Step 3: Reduce the stirring speed to 150 r / min, add L-lactic acid and Lactobacillus acidophilus fermentation products, stir for 15 min, and keep the temperature below 45℃; Step 4: Keep the temperature at 35~40℃, add nisin, cranberry extract, polyhexamethylene biguanide hydrochloride, and β-cyclodextrin-encapsulated tea tree oil in sequence, stir at 200r / min for 30min.

[0049] Step 5: Add dipotassium glycyrrhizate, allantoin, and citrus extract, and stir for 15 minutes until the system is uniform and transparent.

[0050] Step 6: Adjust the pH of the system to 3.8-4.5 using 0.1 mol / L lactic acid or sodium hydroxide solution.

[0051] Add the remaining 20 parts of purified water to bring the volume to 100 parts, and continue stirring for 10 minutes.

[0052] Step 7: Turn off the stirring and let it stand for 20 minutes to remove air bubbles from the system, so as to avoid air bubble residue after soaking the wet wipes, which would affect the user experience.

[0053] The composite nonwoven fabric substrate contains 60 parts viscose fiber, 25 parts activated chitosan fiber, and 15 parts food-grade polyester staple fiber. The preparation process includes the following steps: Step 1: Add the three types of fibers to the opening machine in proportion, set the opening speed to 300 r / min, and the time to 15 min.

[0054] Step 2: After mixing, the mixture is conveyed to the carding machine by airflow. The cylinder speed of the carding machine is controlled at 600 r / min and the working roller speed is controlled at 150 r / min to card it into a uniform fiber web with a web weight of 45 g / m².

[0055] Step 3: The hydroentangling process adopts a three-stage hydroentangling technique. First stage: Low-pressure hydroentanglement, with the pressure set at 8MPa, initially entangles the fibers to form a basic web blank; Second stage: medium-pressure hydroentanglement, with a pressure set at 12MPa, to strengthen the entanglement between fibers and improve the tensile strength of the substrate; The third stage: high-pressure hydroentangling, with the pressure set at 18MPa, allows the chitosan fibers to be evenly distributed on the surface of the substrate, enhancing the antibacterial properties of the surface.

[0056] The water used in the spunlace process is purified water, and the water temperature is controlled at 25℃ to avoid high temperature damaging the chitosan structure.

[0057] Step 4: Drying and shaping. Send the hydroentangled fiber web into a hot air dryer, set the temperature to 80℃, the air speed to 2m / s, and dry for 20 minutes to control the moisture content of the substrate to 5%~8% after drying.

[0058] Step 5: After drying, hot rolling and shaping are carried out at a temperature of 110℃ and a pressure of 0.3MPa.

[0059] Step 6: Cut the shaped nonwoven fabric into rolls 15cm wide.

[0060] The following three aspects need to be noted during the production of composite nonwoven fabric substrates: (1) In step one, the three types of fibers are put into the opening machine in proportion to ensure that the fibers are fully loosened and mixed evenly to avoid fiber clumping; (2) In step two, the mesh weight is easily damaged if it is too low, and affects the water absorption if it is too high. The mesh weight is controlled at 45g / ㎡. (3) The design of hot rolling and shaping after drying in step five can improve the dimensional stability of the substrate and avoid subsequent impregnation shrinkage.

[0061] During the production process of Examples 4-5, aseptic control must be implemented for the preparation of the impregnation solution and the forming of the wet wipes. Specifically, this must be carried out in a Class 10,000 clean area, and operators must wear sterile clothing and gloves to avoid human contamination. The temperature of the impregnation solution preparation should not exceed 45°C throughout the process to prevent the inactivation of active ingredients; the substrate drying temperature should not exceed 80°C to prevent the degradation of chitosan fibers. Furthermore, since excessively high temperatures can easily breed harmful bacteria in wet wipes, while excessively low temperatures can easily irritate the mucous membranes of the private parts, the pH of the impregnation solution must be strictly controlled between 3.8 and 4.5.

[0062] Finally, it should be noted that the above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Although the present invention has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present invention should be included within the protection scope of the present invention.

Claims

1. A feminine hygiene wipe containing an antibacterial composition, characterized in that, The feminine hygiene wipes containing an antibacterial composition comprise a composite nonwoven fabric substrate and an impregnation liquid. The impregnation liquid includes: an antibacterial composition, a soothing and anti-inflammatory agent, a moisturizing and repairing agent, an odor-regulating agent, a solubilizer, and a stabilizer. The feminine hygiene wipes containing the antibacterial composition, by weight, include 0.01-0.03 parts of nisin, 0.1-0.3 parts of cranberry extract, 0.02-0.05 parts of polyhexamethylene biguanide hydrochloride, and 0.05-0.05 parts of β-cyclodextrin-encapsulated tea tree oil. 0.10 parts; the soothing and anti-inflammatory agent is 0.1-0.25 parts of dipotassium glycyrrhizate and 0.05-0.15 parts of allantoin; the moisturizing and repairing agent is 0.03-0.08 parts of small molecule sodium hyaluronate and 0.02-0.06 parts of ceramide 3; the deodorizing and regulating agent includes 0.1-0.3 parts of citrus extract and 0.1-0.3 parts of citric acid-sodium citrate buffer; the solubilizer and stabilizer are 1.0-2.0 parts of glycerin and 0.01-0.03 parts of disodium EDTA.

2. The feminine hygiene wipes containing an antibacterial composition according to claim 1, characterized in that, The feminine wipes containing the antibacterial composition also contain 0.2 to 0.5 parts of L-lactic acid and 0.5 to 1.0 parts of Lactobacillus acidophilus fermentation product.

3. The feminine hygiene wipes containing an antibacterial composition according to claim 1, characterized in that, The feminine wipes containing the antibacterial composition also contain a preservative, namely methylparaben, in a content of 0.05 to 0.1 parts.

4. The feminine hygiene wipes containing an antibacterial composition according to claim 1, characterized in that, The feminine hygiene wipes containing the antibacterial composition, calculated by weight, include the following components: 0.02 parts nisin, 0.2 parts cranberry extract, 0.03 parts polyhexamethylene biguanide hydrochloride, and 0.08 parts β-cyclodextrin-encapsulated tea tree oil; 0.2 parts dipotassium glycyrrhizate and 0.1 parts allantoin as the soothing and anti-inflammatory agents; 0.05 parts sodium hyaluronate and 0.04 parts ceramide 3 as the moisturizing and repairing agents; 0.2 parts citrus extract and 0.2 parts citric acid-sodium citrate buffer as the deodorizing agents; 1.5 parts glycerin, 0.02 parts disodium EDTA, 0.35 parts L-lactic acid, 0.8 parts Lactobacillus acidophilus fermentation product, and 0.08 parts methylparaben; the remainder is purified water.

5. The feminine hygiene wipes containing an antibacterial composition according to claim 1, characterized in that, The impregnation ratio of the impregnation liquid to the substrate is 1:3 to 1:

5.

6. The feminine hygiene wipes containing an antibacterial composition according to claim 1, characterized in that, The impregnation ratio of the impregnation liquid to the substrate is 1:

4.

7. A method for manufacturing feminine hygiene wipes containing an antibacterial composition, used to manufacture the feminine hygiene wipes containing an antibacterial composition as described in any one of claims 1-6, wherein, The steps for preparing the impregnation solution are as follows: Step 1: Add 80 parts of purified water to a vacuum mixing tank, heat to 40°C, add citric acid-sodium citrate buffer and disodium EDTA, stir at 200 r / min for 10 min until completely dissolved; Step 2: Keep the temperature at 40℃, add glycerol, sodium hyaluronate (small molecule), and ceramide 3 in sequence, increase the stirring speed to 300r / min, and stir for 20min; Step 3: Reduce the stirring speed to 150 r / min, add L-lactic acid and Lactobacillus acidophilus fermentation products, stir for 15 min, and keep the temperature below 45℃; Step 4: Keep the temperature at 35~40℃, add nisin, cranberry extract, polyhexamethylene biguanide hydrochloride, and β-cyclodextrin-encapsulated tea tree oil in sequence, stir at 200r / min for 30min; Step 5: Add dipotassium glycyrrhizate, allantoin, and citrus extract, and stir for 15 minutes until the system is uniform and transparent; Step 6: Adjust the pH of the system to 3.8-4.5 using a 0.1 mol / L lactic acid or sodium hydroxide solution; Add the remaining 20 parts of purified water to a final volume of 100 parts, and continue stirring for 10 minutes; Step 7: Turn off the stirring and let it stand for 20 minutes to remove air bubbles.

8. The method for manufacturing feminine hygiene wipes containing an antibacterial composition according to claim 7, characterized in that, In step four, the time interval between the addition of nisin and polyhexamethylene biguanide hydrochloride is 5 minutes.