Traditional Chinese medicine composition for treating chest wall soft tissue contusion and preparation method and application thereof
By utilizing the qi-regulating and blood-activating effects of the traditional Chinese medicine composition, the problems of insignificant treatment effects for chest wall soft tissue contusions and adverse reactions of non-steroidal anti-inflammatory drugs were solved, achieving rapid relief of pain and swelling, and improving treatment efficacy and quality of life.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-12-26
- Publication Date
- 2026-04-07
AI Technical Summary
In existing technologies, the treatment effect of chest wall soft tissue contusion is not significant, and long-term use of nonsteroidal anti-inflammatory drugs can cause adverse reactions, affecting the patient's quality of life.
A traditional Chinese medicine composition is used, including Cyperus rotundus, Aucklandia lappa, Curcuma longa, Paeonia lactiflora, Angelica sinensis, Perilla frutescens stem, Amomum villosum, Citrus aurantium, Sparganium stoloniferum, Curcuma zedoaria, Fritillaria thunbergii, Prunus armeniaca, Citrus reticulata peel, and Corydalis yanhusuo. These are decocted and concentrated to form pills, granules, and other dosage forms to promote the rapid repair of chest wall soft tissues.
The traditional Chinese medicine composition can significantly relieve pain, swelling and ecchymosis, improve treatment efficacy, reduce adverse reactions and improve patients' quality of life by promoting blood circulation, soothing the liver and regulating qi.
Abstract
Description
Technical Field
[0001] This invention belongs to the field of traditional Chinese medicine technology, specifically relating to a traditional Chinese medicine composition for treating chest wall soft tissue contusions, its preparation method, and its application. Background Technology
[0002] Chest injuries, also known as blunt force trauma to the chest or soft tissue contusions of the chest wall, belong to soft tissue injuries and are classified as trauma. They are mainly caused by blunt force trauma, such as falls, blows, bumps, and collisions, directly impacting the chest wall. Because the chest wall contains abundant capillaries, segmental intercostal nerves, and lymph nodes in its deep and superficial structures, unlike the limbs and joints which have rich and well-developed muscle tissue and strong ligament structures, the anatomical structures on both sides of the thorax are relatively weak. Therefore, the clinical symptoms of chest injuries are often mainly pain, swelling, and subcutaneous ecchymosis, accompanied by pain induced by breathing, coughing, or strenuous activity. With the advancement of modern technology and economic development, the population is constantly increasing, and the number of vehicles is skyrocketing. Trauma caused by traffic accidents, construction work, and other factors is constantly increasing, and trauma has become the third leading cause of death across all age groups, after cardiovascular disease and cancer.
[0003] In clinical practice, chest injuries are usually not treated with specific interventions, but rather with symptomatic treatment such as oral nonsteroidal anti-inflammatory drugs (NSAIDs). Although there are many types of NSAIDs that can inhibit the synthesis of pain-causing compounds through different pathways and achieve some effect in the short term, most patients do not experience significant improvement in their overall condition. Symptoms such as pain, swelling, bruising, and limited mobility can persist for several weeks. Furthermore, long-term use of NSAIDs can also cause adverse reactions such as gastrointestinal symptoms, bleeding, dizziness, and tinnitus, seriously affecting patients' sleep, quality of life, and mental health. Summary of the Invention
[0004] To address the aforementioned shortcomings in the prior art, this invention provides a traditional Chinese medicine composition for treating chest wall soft tissue contusions, its preparation method, and its application. The components of this traditional Chinese medicine composition work synergistically to promote rapid repair of chest wall soft tissue and improve treatment efficacy.
[0005] To achieve the above objectives, the technical solution adopted by the present invention to solve its technical problem is as follows:
[0006] A traditional Chinese medicine composition for treating soft tissue contusions of the chest wall, comprising the following components in parts by weight: Cyperus rotundus 80-140 parts, Aucklandia lappa 80-140 parts, Curcuma longa 80-140 parts, Paeonia lactiflora 80-140 parts, Angelica sinensis 80-140 parts, Perilla frutescens stem 80-140 parts, Amomum villosum 80-140 parts, Citrus aurantium 100-160 parts, Sparganium stoloniferum 80-140 parts, Curcuma zedoaria 80-140 parts, Fritillaria thunbergii 80-140 parts, Prunus armeniaca 80-140 parts, Citrus reticulata peel 80-140 parts, Corydalis yanhusuo 80-140 parts, or Panax notoginseng powder 80-140 parts.
[0007] Further, it includes the following components in parts by weight: Cyperus rotundus 100-120 parts, Aucklandia lappa 100-120 parts, Curcuma longa 100-120 parts, Paeonia lactiflora 100-120 parts, Angelica sinensis 100-120 parts, Perilla frutescens stem 100-120 parts, Amomum villosum 100-120 parts, Citrus aurantium 115-145 parts, Sparganium stoloniferum 100-120 parts, Curcuma zedoaria 100-120 parts, Fritillaria thunbergii 100-120 parts, Prunus armeniaca 100-120 parts, Citrus reticulata peel 100-120 parts, Corydalis yanhusuo 100-120 parts or Panax notoginseng powder 100-120 parts.
[0008] Further, it includes the following components in parts by weight: Cyperus rotundus 111.1 parts, Aucklandia lappa 111.1 parts, Curcuma longa 111.1 parts, Paeonia lactiflora 111.1 parts, Angelica sinensis 111.1 parts, Perilla frutescens stem 111.1 parts, Amomum villosum 111.1 parts, Citrus aurantium 133.3 parts, Sparganium stoloniferum 111.1 parts, Curcuma zedoaria 111.1 parts, Fritillaria thunbergii 111.1 parts, Prunus armeniaca 111.1 parts, Citrus reticulata peel 111.1 parts, Corydalis yanhusuo 111.1 parts or Panax notoginseng powder 111.1 parts.
[0009] Further, it includes the following components in parts by weight: 120 parts Cyperus rotundus, 100 parts Aucklandia lappa, 120 parts Curcuma longa, 120 parts Paeonia lactiflora, 100 parts Angelica sinensis, 100 parts Perilla frutescens stem, 120 parts Amomum villosum, 145 parts Citrus aurantium, 100 parts Sparganium stoloniferum, 100 parts Curcuma zedoaria, 100 parts Fritillaria thunbergii, 120 parts Prunus armeniaca, 100 parts Citrus reticulata peel, 120 parts Corydalis yanhusuo, or 120 parts Panax notoginseng powder.
[0010] Further, it includes the following components in parts by weight: 100 parts Cyperus rotundus, 120 parts Aucklandia lappa, 100 parts Curcuma longa, 100 parts Paeonia lactiflora, 120 parts Angelica sinensis, 120 parts Perilla frutescens stem, 100 parts Amomum villosum, 115 parts Citrus aurantium, 120 parts Sparganium stoloniferum, 120 parts Curcuma zedoaria, 120 parts Fritillaria thunbergii, 100 parts Prunus armeniaca, 120 parts Citrus reticulata peel, 100 parts Corydalis yanhusuo, or 100 parts Panax notoginseng powder.
[0011] Furthermore, Cyperus rotundus is prepared by vinegar, Citrus aurantium is prepared by stir-frying Citrus aurantium with wheat bran, Sparganium stoloniferum is prepared by vinegar, Curcuma zedoaria is prepared by vinegar, bitter almond is prepared by simmering bitter almond, and Corydalis yanhusuo is prepared by vinegar.
[0012] The preparation method of the above-mentioned traditional Chinese medicine composition for treating chest wall soft tissue contusion includes the following steps: mixing the raw materials after pulverizing them; or preparing an extract by mixing or extracting the raw materials individually; or preparing an active ingredient by further refining and purifying the extract; or preparing an extract / active ingredient by adding pharmaceutically acceptable excipients.
[0013] Furthermore, the dosage form produced is one of the following: pills, granules, capsules, powders, mixtures, tablets, granules, or oral liquids.
[0014] Furthermore, the specific preparation method is as follows: The above fifteen ingredients are crushed into coarse powder, and then boiled three times with water along with the other thirteen ingredients except for Panax notoginseng powder. The decoctions are combined, filtered, and the filtrate is concentrated to a relative density of 1.15-1.25. Granulation is then carried out with Panax notoginseng powder and an appropriate amount of pharmaceutically acceptable excipients to obtain the final product.
[0015] The above-mentioned traditional Chinese medicine composition is used in the preparation of a drug for treating soft tissue contusions of the chest wall.
[0016] The beneficial effects of this invention are as follows:
[0017] In this invention, Cyperus rotundus has the functions of soothing the liver, regulating qi, relieving depression, promoting qi circulation, and relieving pain, and is used as the principal herb.
[0018] Costus root has the effect of promoting qi circulation and relieving pain. Together with Cyperus rhizome, it enhances the liver-soothing and qi-regulating power. The two work together to resolve the core problem of qi stagnation. Amomum villosum has the functions of resolving dampness, stimulating appetite, warming the spleen and stopping diarrhea. It can help Cyperus rhizome promote qi circulation and resolve stagnation, and also treat dampness obstructing the middle jiao. Costus root and Amomum villosum work together to assist in the smooth flow of qi. Sparganium rhizome breaks up blood stasis, and Curcuma zedoaria promotes qi circulation. Together, they enhance the effects of promoting blood circulation, relieving pain, dispersing blood stasis and breaking up nodules. Panax notoginseng resolves blood stasis, stops bleeding, promotes blood circulation and relieves pain. This makes the prescription promote blood circulation without harming the body's vital energy, and also has a hemostatic effect. All of the above are assistant herbs.
[0019] Dried tangerine peel has the effect of drying dampness and resolving phlegm, while immature bitter orange peel has the effect of regulating qi and relieving chest congestion. Together, they regulate the qi stagnation of the spleen and stomach. Perilla stem regulates qi and relieves chest congestion, harmonizing the spleen and stomach. Red peony root clears heat, cools blood, and removes blood stasis, while angelica root nourishes blood, invigorates blood, and harmonizes qi and blood, preventing blood-activating drugs from damaging the body's vital energy. Turmeric promotes qi and relieves depression, assisting cyperus and costus root in enhancing the effects of regulating qi and soothing the liver, while also treating blood heat and blood stasis, paving the way for blood-activating drugs and avoiding the situation where qi is simply regulated without blood activation, resulting in "qi flowing in vain but blood stasis not dissipating." Fritillaria thunbergii clears phlegm and heat, assisting the principal drug in soothing the liver, while bitter almond stops cough and relieves asthma, promotes lung qi, and helps regulate qi, while also preventing qi-regulating drugs from being too drying and damaging yin. All of the above are adjuvant drugs.
[0020] Corydalis promotes qi and blood circulation, removes blood stasis, and can enhance the analgesic effect of Cyperus rotundus, thus serving as an adjuvant herb.
[0021] The above-mentioned drugs work synergistically. The qi-regulating drugs clear qi stagnation and promote the blood-activating drugs to reach the injured site. The blood-activating drugs remove obstacles for the qi-regulating drugs and enhance their effects. The lung-clearing drugs improve the overall qi mechanism and promote physical recovery. The combined effect of these drugs is to achieve a good therapeutic effect on contusions of the entire chest tissue. Detailed Implementation
[0022] To make the objectives, technical solutions, and advantages of this invention clearer, the invention will be further described in detail below with reference to embodiments. It should be understood that the specific embodiments described herein are only for explaining the invention and are not intended to limit the invention; that is, the described embodiments are merely some embodiments of the invention, and not all embodiments.
[0023] Therefore, the following detailed description of the embodiments of the present invention is not intended to limit the scope of the claimed invention, but merely to illustrate selected embodiments of the invention. All other embodiments obtained by those skilled in the art based on the embodiments of the present invention without inventive effort are within the scope of protection of the present invention.
[0024] It should be noted that relational terms such as "first" and "second" are used merely to distinguish one entity or operation from another, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Furthermore, the terms "comprising," "including," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such process, method, article, or apparatus. Unless otherwise specified, an element defined by the phrase "comprising one..." does not exclude the presence of other identical elements in the process, method, article, or apparatus that includes the element.
[0025] The features and performance of the present invention will be further described in detail below with reference to embodiments.
[0026] Example 1
[0027] A traditional Chinese medicine composition for treating soft tissue contusions of the chest wall, comprising the following components in parts by weight: 140 parts of vinegar-processed Cyperus rotundus, 80 parts of Aucklandia lappa, 140 parts of Curcuma longa, 140 parts of Paeonia lactiflora, 80 parts of Angelica sinensis, 80 parts of Perilla frutescens stem, 140 parts of Amomum villosum, 160 parts of wheat bran-fried Citrus aurantium, 80 parts of vinegar-processed Sparganium stoloniferum, 80 parts of vinegar-processed Curcuma zedoaria, 140 parts of Fritillaria thunbergii, 140 parts of scalded bitter almond, 80 parts of Citrus reticulata peel, 140 parts of vinegar-processed Corydalis yanhusuo, or 140 parts of Panax notoginseng powder.
[0028] The specific preparation method of the above-mentioned traditional Chinese medicine composition for treating soft tissue contusion of the chest wall is as follows: The above fifteen ingredients, bitter almond powder, are crushed into coarse powder, and decocted three times with water, except for Panax notoginseng powder, for 1.5 hours each time. The decoctions are combined, filtered, and the filtrate is concentrated to a relative density of 1.15-1.25. The filtrate is then granulated with Panax notoginseng powder and an appropriate amount of dextrin to obtain the final product.
[0029] Example 2
[0030] A traditional Chinese medicine composition for treating soft tissue contusions of the chest wall, comprising the following components in parts by weight: 80 parts of vinegar-processed Cyperus rotundus, 140 parts of Aucklandia lappa, 80 parts of Curcuma longa, 80 parts of Paeonia lactiflora, 140 parts of Angelica sinensis, 140 parts of Perilla frutescens stem, 80 parts of Amomum villosum, 100 parts of wheat bran-fried Citrus aurantium, 140 parts of vinegar-processed Sparganium stoloniferum, 140 parts of vinegar-processed Curcuma zedoaria, 80 parts of Fritillaria thunbergii, 80 parts of scorched Prunus armeniaca, 140 parts of Citrus reticulata peel, 80 parts of vinegar-processed Corydalis yanhusuo, or 80 parts of Panax notoginseng powder.
[0031] The specific preparation method of the above-mentioned traditional Chinese medicine composition for treating soft tissue contusion of the chest wall is as follows: The above fifteen ingredients, bitter almond powder, are crushed into coarse powder, and decocted three times with water, except for Panax notoginseng powder, for 1.5 hours each time. The decoctions are combined, filtered, and the filtrate is concentrated to a relative density of 1.15-1.25. The filtrate is then granulated with Panax notoginseng powder and an appropriate amount of dextrin to obtain the final product.
[0032] Example 3
[0033] A traditional Chinese medicine composition for treating soft tissue contusions of the chest wall, comprising the following components in parts by weight: 120 parts of vinegar-processed Cyperus rotundus, 100 parts of Aucklandia lappa, 120 parts of Curcuma longa, 120 parts of Paeonia lactiflora, 100 parts of Angelica sinensis, 100 parts of Perilla frutescens stem, 120 parts of Amomum villosum, 145 parts of wheat bran-fried Citrus aurantium, 100 parts of vinegar-processed Sparganium stoloniferum, 100 parts of vinegar-processed Curcuma zedoaria, 100 parts of Fritillaria thunbergii, 120 parts of scalded bitter almond, 100 parts of Citrus reticulata peel, 120 parts of vinegar-processed Corydalis yanhusuo, or 120 parts of Panax notoginseng powder.
[0034] The specific preparation method of the above-mentioned traditional Chinese medicine composition for treating soft tissue contusion of the chest wall is as follows: The above fifteen ingredients, bitter almond powder, are crushed into coarse powder, and decocted three times with water, except for Panax notoginseng powder, for 1.5 hours each time. The decoctions are combined, filtered, and the filtrate is concentrated to a relative density of 1.15-1.25. The filtrate is then granulated with Panax notoginseng powder and an appropriate amount of dextrin to obtain the final product.
[0035] Example 4
[0036] A traditional Chinese medicine composition for treating soft tissue contusions of the chest wall, comprising the following components in parts by weight: 100 parts of vinegar-processed Cyperus rotundus, 120 parts of Aucklandia lappa, 100 parts of Curcuma longa, 100 parts of Paeonia lactiflora, 120 parts of Angelica sinensis, 120 parts of Perilla frutescens stem, 100 parts of Amomum villosum, 115 parts of wheat bran-fried Citrus aurantium, 120 parts of vinegar-processed Sparganium stoloniferum, 120 parts of vinegar-processed Curcuma zedoaria, 120 parts of Fritillaria thunbergii, 100 parts of scalded bitter almond, 120 parts of Citrus reticulata peel, 100 parts of vinegar-processed Corydalis yanhusuo, or 100 parts of Panax notoginseng powder.
[0037] The specific preparation method of the above-mentioned traditional Chinese medicine composition for treating soft tissue contusion of the chest wall is as follows: The above fifteen ingredients, bitter almond powder, are crushed into coarse powder, and decocted three times with water, except for Panax notoginseng powder, for 1.5 hours each time. The decoctions are combined, filtered, and the filtrate is concentrated to a relative density of 1.15-1.25. The filtrate is then granulated with Panax notoginseng powder and an appropriate amount of dextrin to obtain the final product.
[0038] Example 5
[0039] A traditional Chinese medicine composition for treating soft tissue contusions of the chest wall, comprising the following components in parts by weight: 111.1 parts of vinegar-processed Cyperus rotundus, 111.1 parts of Aucklandia lappa, 111.1 parts of Curcuma longa, 111.1 parts of Paeonia lactiflora, 111.1 parts of Angelica sinensis, 111.1 parts of Perilla frutescens stem, 111.1 parts of Amomum villosum, 133.3 parts of wheat bran-fried Citrus aurantium, 111.1 parts of vinegar-processed Sparganium stoloniferum, 111.1 parts of vinegar-processed Curcuma zedoaria, 111.1 parts of Fritillaria thunbergii, 111.1 parts of scalded bitter almond, 111.1 parts of Citrus reticulata peel, 111.1 parts of vinegar-processed Corydalis yanhusuo, or 111.1 parts of Panax notoginseng powder.
[0040] The specific preparation method of the above-mentioned traditional Chinese medicine composition for treating soft tissue contusion of the chest wall is as follows: The above fifteen ingredients, bitter almond powder, are crushed into coarse powder, and decocted three times with water, except for Panax notoginseng powder, for 1.5 hours each time. The decoctions are combined, filtered, and the filtrate is concentrated to a relative density of 1.15-1.25. The filtrate is then granulated with Panax notoginseng powder and an appropriate amount of dextrin to obtain the final product.
[0041] Comparative Example 1
[0042] A traditional Chinese medicine composition for treating soft tissue contusions of the chest wall, comprising the following components in parts by weight: 111.1 parts of vinegar-processed Cyperus rotundus, 111.1 parts of Curcuma longa, 111.1 parts of Paeonia lactiflora, 111.1 parts of Angelica sinensis, 111.1 parts of Perilla frutescens stem, 111.1 parts of Amomum villosum, 133.3 parts of wheat bran-fried Citrus aurantium, 155.5 parts of vinegar-processed Sparganium stoloniferum, 66.6 parts of vinegar-processed Curcuma zedoaria, 111.1 parts of Fritillaria thunbergii, 111.1 parts of Citrus reticulata peel, 111.1 parts of vinegar-processed Corydalis yanhusuo, or 111.1 parts of Panax notoginseng powder.
[0043] The specific preparation method of the above-mentioned traditional Chinese medicine composition for treating soft tissue contusion of the chest wall is as follows: The above thirteen ingredients, together with the other twelve ingredients except for Panax notoginseng powder, are decocted three times with water, each time for 1.5 hours. The decoctions are combined, filtered, and the filtrate is concentrated to a relative density of 1.15-1.25. The filtrate is then granulated with Panax notoginseng powder and an appropriate amount of dextrin to obtain the final product.
[0044] Comparative Example 2
[0045] A traditional Chinese medicine composition for treating soft tissue contusions of the chest wall, comprising the following components in parts by weight: 155.5 parts of vinegar-processed Cyperus rotundus, 66.6 parts of Aucklandia lappa, 111.1 parts of Curcuma longa, 111.1 parts of Paeonia lactiflora, 111.1 parts of Salvia miltiorrhiza, 111.1 parts of Perilla frutescens stem, 111.1 parts of Amomum villosum, 133.3 parts of Citrus medica, 111.1 parts of vinegar-processed Sparganium stoloniferum, 111.1 parts of vinegar-processed Curcuma zedoaria, 111.1 parts of Fritillaria thunbergii, 111.1 parts of scalded bitter almond, 111.1 parts of Citrus reticulata peel, 111.1 parts of vinegar-processed Corydalis yanhusuo, and 111.1 parts of Panax notoginseng powder.
[0046] The specific preparation method of the above-mentioned traditional Chinese medicine composition for treating soft tissue contusion of the chest wall is as follows: The above fifteen ingredients, bitter almond powder, are crushed into coarse powder, and decocted three times with water, except for Panax notoginseng powder, for 1.5 hours each time. The decoctions are combined, filtered, and the filtrate is concentrated to a relative density of 1.15-1.25. The filtrate is then granulated with Panax notoginseng powder and an appropriate amount of dextrin to obtain the final product.
[0047] Test case
[0048] I. General Information
[0049] We collected data from patients with chest wall contusions who visited our hospital. There were 45 males and 35 females with an average age of 46.7 years.
[0050] II. Disease Diagnostic Criteria
[0051] 1. Core medical history and symptoms
[0052] History of trauma: blunt force trauma to the chest;
[0053] Pain characteristics: local dull or throbbing pain, which worsens with pressure or movement, but does not significantly aggravate with breathing or coughing;
[0054] The pain is localized and has no or only slight radiating effect to the shoulder and back.
[0055] Bruising, swelling, or subcutaneous hematoma may be visible on the skin;
[0056] It may be accompanied by mild breathing restriction, but without severe breathing difficulties or coughing up blood.
[0057] 2. Physical examination
[0058] Palpation: There is significant tenderness at the injured site, but no crepitus or abnormal movement.
[0059] Thoracic compression test: Gently press the front, back or sides of the thorax with both hands. If the local pain worsens but there is no bony friction, it suggests soft tissue injury.
[0060] Breathing movements: Chest range of motion is basically normal, with no paradoxical breathing.
[0061] 3. Imaging examinations
[0062] X-ray or CT scan: No rib or sternal fractures, or complications such as pneumothorax or hemothorax, but may show local soft tissue swelling or hematoma.
[0063] III. Administration Method
[0064] The patients were randomly divided into 4 groups of 20 each. Each group of patients was given the drugs in Example 5, Comparative Example 1, and Comparative Example 2, as well as ibuprofen capsules, 15g per bag, 1 bag each time, 3 times a day, for 1 week. The patients' treatment was observed. See Table 1 for details.
[0065] IV. Criteria for Evaluating Therapeutic Effect
[0066] Pain: The visual analog scale (VAS) was used to quantify the degree of pain (0 points = no pain, 10 points = severe pain), and the degree of pain before and after treatment was recorded.
[0067] Local signs: swelling, ecchymosis, and tenderness;
[0068] Functions: Chest movement, everyday clothing;
[0069] Cured: VAS score dropped to 0, no spontaneous pain, no pain upon pressure, swelling and ecchymosis completely subsided, no local tenderness, normal chest movement, and no restriction on daily activities;
[0070] Improvement: VAS score drops below 3, only occurs during strenuous activity, swelling subsides by 70%, ecchymosis lightens in color, mild local tenderness, daily activities are unrestricted, and occasional discomfort occurs during strenuous activity or special movements;
[0071] Not cured: VAS score is still greater than 4, pain persists even at rest, or pain does not improve or even worsens, swelling and ecchymosis subside by less than 30%, local tenderness is obvious, chest movement is restricted, and daily activities are affected.
[0072] Effectiveness rate (%) = (Number of cured patients + Number of patients who improved) / Total number of patients * 100%
[0073] V. Treatment Efficacy
[0074] Table 1:
[0075] Group Number of people cured Number of people whose condition has improved (people) Number of people not yet recovered (persons) Effectiveness (%) Example 5 15 5 0 100% Comparative Example 1 3 8 9 55% Comparative Example 2 4 9 7 65% Ibuprofen capsules 7 6 7 65%
[0076] The data in the table above shows that the drug in Example 5 has a good therapeutic effect on soft tissue contusions of the chest. However, in Comparative Examples 1 and 2, the formulation ratios were adjusted. The treatment results show that the therapeutic effect of the adjusted formulations was worse than that of the formulation in Example 5, with a significantly lower effective rate. It is speculated that the adjustment of the formulation may have weakened or eliminated the synergistic relationship between the medicinal materials, thus affecting the final therapeutic effect.
Claims
1. A traditional Chinese medicine composition for treating soft tissue contusions of the chest wall, characterized in that, The formula includes the following components by weight: Cyperus rotundus 80-140 parts, Aucklandia lappa 80-140 parts, Curcuma longa 80-140 parts, Paeonia lactiflora 80-140 parts, Angelica sinensis 80-140 parts, Perilla frutescens stem 80-140 parts, Amomum villosum 80-140 parts, Citrus aurantium 100-160 parts, Sparganium stoloniferum 80-140 parts, Curcuma zedoaria 80-140 parts, Fritillaria thunbergii 80-140 parts, Prunus armeniaca 80-140 parts, Citrus reticulata peel 80-140 parts, Corydalis yanhusuo 80-140 parts or Panax notoginseng powder 80-140 parts.
2. The traditional Chinese medicine composition for treating chest wall soft tissue contusions as described in claim 1, characterized in that, The formula includes the following components by weight: Cyperus rotundus 100-120 parts, Aucklandia lappa 100-120 parts, Curcuma longa 100-120 parts, Paeonia lactiflora 100-120 parts, Angelica sinensis 100-120 parts, Perilla frutescens stem 100-120 parts, Amomum villosum 100-120 parts, Citrus aurantium 115-145 parts, Sparganium stoloniferum 100-120 parts, Curcuma zedoaria 100-120 parts, Fritillaria thunbergii 100-120 parts, Prunus armeniaca 100-120 parts, Citrus reticulata peel 100-120 parts, Corydalis yanhusuo 100-120 parts or Panax notoginseng powder 100-120 parts.
3. The traditional Chinese medicine composition for treating chest wall soft tissue contusions as described in claim 1, characterized in that, The product comprises the following components in parts by weight: Cyperus rotundus 111.1 parts, Aucklandia lappa 111.1 parts, Curcuma longa 111.1 parts, Paeonia lactiflora 111.1 parts, Angelica sinensis 111.1 parts, Perilla frutescens stem 111.1 parts, Amomum villosum 111.1 parts, Citrus aurantium 133.3 parts, Sparganium stoloniferum 111.1 parts, Curcuma zedoaria 111.1 parts, Fritillaria thunbergii 111.1 parts, Prunus armeniaca 111.1 parts, Citrus reticulata peel 111.1 parts, Corydalis yanhusuo 111.1 parts or Panax notoginseng powder 111.1 parts.
4. The traditional Chinese medicine composition for treating chest wall soft tissue contusions as described in claim 1, characterized in that, The formula includes the following components by weight: Cyperus rotundus 120 parts, Aucklandia lappa 100 parts, Curcuma longa 120 parts, Paeonia lactiflora 120 parts, Angelica sinensis 100 parts, Perilla frutescens stem 100 parts, Amomum villosum 120 parts, Citrus aurantium 145 parts, Sparganium stoloniferum 100 parts, Curcuma zedoaria 100 parts, Fritillaria thunbergii 100 parts, Prunus armeniaca 120 parts, Citrus reticulata peel 100 parts, Corydalis yanhusuo 120 parts or Panax notoginseng powder 120 parts.
5. The traditional Chinese medicine composition for treating soft tissue contusions of the chest wall as described in claim 1, characterized in that, The formula includes the following components by weight: Cyperus rotundus 100 parts, Aucklandia lappa 120 parts, Curcuma longa 100 parts, Paeonia lactiflora 100 parts, Angelica sinensis 120 parts, Perilla frutescens stem 120 parts, Amomum villosum 100 parts, Citrus aurantium 115 parts, Sparganium stoloniferum 120 parts, Curcuma zedoaria 120 parts, Fritillaria thunbergii 120 parts, Prunus armeniaca 100 parts, Citrus reticulata peel 120 parts, Corydalis yanhusuo 100 parts or Panax notoginseng powder 100 parts.
6. The traditional Chinese medicine composition for treating soft tissue contusions of the chest wall as described in any one of claims 1-5, characterized in that, The Cyperus rotundus is vinegar-processed Cyperus rotundus, the Citrus aurantium is wheat bran-fried Citrus aurantium, the Sparganium stoloniferum is vinegar-processed Sparganium stoloniferum, the Curcuma zedoaria is vinegar-processed Curcuma zedoaria, the bitter almond is blanched bitter almond, and the Corydalis yanhusuo is vinegar-processed Corydalis yanhu 7. A method for preparing the traditional Chinese medicine composition for treating chest wall soft tissue contusions according to any one of claims 1-6, characterized in that, Includes the following steps: It is made by pulverizing and mixing various raw materials; or by extracting the raw materials by mixing or extracting them individually; or by further refining and purifying the extract to obtain the active ingredient; or by adding pharmaceutically acceptable excipients to the extract / active ingredient.
8. The method for preparing the traditional Chinese medicine composition for treating chest wall soft tissue contusions as described in claim 7, characterized in that, The dosage form produced is one of the following: pills, granules, capsules, powders, mixtures, tablets, granules, or oral liquids.
9. The method for preparing the traditional Chinese medicine composition for treating chest wall soft tissue contusions as described in claim 7, characterized in that, The specific preparation method is as follows: The above fifteen ingredients are crushed into coarse powder, and then boiled three times with water along with the other thirteen ingredients except for Panax notoginseng powder. The decoctions are combined, filtered, and the filtrate is concentrated to a relative density of 1.15-1.
25. The filtrate is then granulated with Panax notoginseng powder and an appropriate amount of pharmaceutically acceptable excipients to obtain the final product.
10. The use of the traditional Chinese medicine composition according to any one of claims 1-7 in the preparation of a medicament for treating chest wall soft tissue contusion.