Preparation method of small-particle-size ecological negative oxygen ions and application of small-particle-size ecological negative oxygen ions in sleep assistance

Abstract

The invention belongs to the technical field of air purification and health intervention, and discloses a preparation method of small-particle-size ecological negative oxygen ions and application of the small-particle-size ecological negative oxygen ions in the aspect of sleep aiding, the preparation method comprises the following steps: 1) performing supercritical COextraction and multi-stage filtration purification compounding on natural plants to prepare a non-toxic and non-irritant negative oxygen ion stock solution; 2) the generating device comprises a low-temperature plasma ion generating module, an air filtering module and an intelligent control module; and 3) mixing the atomized stock solution with clean air, enabling the mixture to enter an ion generation module, and enabling active components to be attached with negative oxygen ions to improve stability and inactivation capability. The prepared negative oxygen ions are small in particle size and can penetrate through a blood brain barrier to adapt to sensitive people; the non-medicine with the concentration of 6000-8000 / cm is used for helping sleep, so that the sleep time is shortened, and the sleep is prolonged; air can be purified, breathing and cardiovascular diseases can be improved in an auxiliary mode, and an efficient and healthy scheme is provided.

Description

Technical Field

[0001] This invention belongs to the field of air purification and health intervention technology, specifically relating to a method for preparing small-particle-size ecological-grade negative oxygen ions and their application in assisting sleep. Background Technology

[0002] With the acceleration of urbanization and the increase in the time spent in enclosed indoor environments, the connection between indoor air quality and human health is becoming increasingly prominent. Currently, most office and residential spaces are under constant air conditioning or with insufficient natural ventilation, leading to the accumulation of air pollutants—including not only suspended particulate matter such as PM2.5, dust, and smoke, but also volatile organic compounds (VOCs) such as formaldehyde, benzene, and TVOCs released from building materials and furniture, along with the proliferation of microorganisms such as bacteria and viruses. These environmental problems not only easily trigger sub-health symptoms such as fatigue and difficulty concentrating, but also become a significant contributing factor to sleep disorders, posing a potential threat to long-term health.

[0003] Negative oxygen ions, often referred to as "air vitamins" for their air purification and health benefits, have gained widespread recognition for their application value. However, existing negative oxygen ion products still suffer from significant technical limitations: Firstly, the particle size control precision of negative oxygen ions is insufficient. Most products generate negative oxygen ions with large particle sizes and low molecular activity, making it difficult for them to penetrate the blood-brain barrier and effectively exert biological effects. They can only act on the surface of the air, resulting in limited health benefits. Secondly, some products add chemical additives to their formulas to improve ion generation efficiency, leading to household corrosion and skin irritation. This severely limits their suitability for sensitive groups such as mothers, infants, and the elderly, failing to meet the requirements for safe use in all scenarios.

[0004] In the field of sleep improvement, existing solutions also have technical shortcomings: drug interventions are effective in the short term, but long-term use can easily lead to dependence and side effects such as liver and kidney damage; traditional physical sleep aids (such as white noise and aromatherapy) can only help people fall asleep by adjusting the environment and atmosphere, but cannot improve the neuroendocrine balance at the physiological level. Their intervention effects on complex types of sleep disorders such as neurasthenia and environmentally sensitive insomnia are unstable, and they are difficult to meet the needs of the population for safe and efficient sleep improvement technologies. Summary of the Invention

[0005] To overcome the above-mentioned technical problems, this invention provides a method for preparing small-particle-size ecological-grade negative oxygen ions and their application in assisting sleep.

[0006] The present invention adopts the following technical solution: Methods for preparing small-particle-size ecological-grade negative oxygen ions include: Preparation of negative oxygen ion stock solution: Using natural plants as raw materials, supercritical CO2 extraction technology is used to extract the active ingredients of the plants. The extracted liquid is filtered and purified in multiple stages to remove impurities and large molecular useless components. The purified concentrated liquids of various plants are compounded in a specific ratio and diluted with deionized water to obtain a non-toxic, non-corrosive, and non-irritating negative oxygen ion stock solution. Negative oxygen ion generating device: includes an ion generating module, an air filtration module, and an intelligent control module; the ion generating module uses low-temperature plasma discharge technology to generate small-particle ecological-grade negative oxygen ions; the air filtration module is used to pre-treat the air entering the device, filtering out large particles of dust and impurities in the air; the intelligent control module has a built-in environmental sensing sensor that can monitor the indoor pollutant concentration and negative oxygen ion concentration in real time, and automatically adjust the ion emission intensity according to the monitoring results. The prepared negative oxygen ion stock solution is injected into the storage tank. After the device is started, the atomization module converts the stock solution into micron-sized droplets, which are then mixed with clean air pretreated by the air filtration module. The air containing the stock solution droplets then enters the ion generation module. When the ion generation module generates small-diameter negative oxygen ions using low-temperature plasma discharge technology, the natural plant active ingredients in the stock solution adhere to the surface of the negative oxygen ions, improving their stability and enhancing their ability to inactivate bacteria and viruses. The small-diameter negative oxygen ions carrying the active ingredients of the stock solution are evenly released into the space through the device's air outlet, ensuring the ecological properties of negative oxygen ions while avoiding the odor or irritation problems that may occur with traditional ion generation methods.

[0007] Preferably, the natural plant includes at least two of ginkgo leaves, mugwort, and mint.

[0008] Preferably, the small-particle-size ecological-grade negative oxygen ions generated by the ion generating module can undergo irregular zigzag Brownian motion in the air, with a migration distance of not less than 5 meters.

[0009] This invention also discloses the application of small-particle-size ecological-grade negative oxygen ions in assisting sleep improvement. The above-mentioned small-particle-size ecological-grade negative oxygen ion generating device is placed in the bedroom environment, and the sleep mode of the device is turned on to maintain the concentration of small-particle-size ecological-grade negative oxygen ions in the bedroom at 6000-8000 ions / cm³. Through this concentration of small-particle-size ecological-grade negative oxygen ions, the human body's serotonin level is regulated, GABA secretion is promoted, and positively charged insomnia factors in the environment are neutralized, thereby achieving the auxiliary improvement of sleep.

[0010] Preferably, the noise level of the small-particle-size ecological-grade negative oxygen ion generator is no higher than 25 decibels when operating in sleep mode.

[0011] Preferably, continuous application of this method for more than 30 days can shorten the time it takes for insomniacs to fall asleep by at least 20 minutes, extend sleep duration by at least 1.5 hours, and reduce the number of times they wake up at night by 2-3 times.

[0012] Preferably, the particle size of the small-diameter ecological-grade negative oxygen ions meets the condition that they can penetrate the human blood-brain barrier to exert biological effects.

[0013] Compared with the prior art, the beneficial effects of the present invention are: This invention overcomes the technical bottlenecks of traditional negative ion products through the synergistic design of a "natural stock solution formula + a dedicated negative ion generating device." In terms of effectiveness, the negative ion generating device employs low-temperature plasma discharge technology, which can precisely control the particle size distribution of negative ions. The generated small-particle, eco-grade negative ion molecules have strong kinetic energy and high activity, achieving wide-range coverage through irregular "Z"-shaped Brownian motion, and possessing the ability to penetrate the human blood-brain barrier, providing a foundation for biological effects. In terms of safety, the negative ion stock solution uses natural plants such as ginkgo leaves, artemisia, and mint as raw materials, prepared through supercritical CO2 extraction, multi-stage filtration purification, and compound dilution processes. Verified by authoritative institutions, it is non-toxic, non-corrosive to household items, and non-irritating to the skin, meeting the long-term use needs of sensitive groups such as mothers, infants, and the elderly, truly achieving the technical goal of "high efficiency and benefit + safety and harmlessness."

[0014] This invention addresses sleep disorders by constructing an intervention program from two dimensions: physiological regulation and environmental optimization, demonstrating significant scientific rationality. Through an intelligent control module, the concentration of small-particle, ecological-grade negative oxygen ions in the bedroom environment is stably maintained at 6000-8000 ions / cm³ (this concentration range matches the concentration of negative oxygen ions in natural forests / waterfall areas, meeting the physiological needs of human sleep). On one hand, it can regulate the body's serotonin levels, reduce sympathetic nerve excitability, and promote the secretion of the natural sedative neurotransmitter (GABA), improving sleep regulation mechanisms at the neuroendocrine level. On the other hand, it can neutralize positively charged insomnia-inducing factors such as electromagnetic radiation products in the environment, optimizing the sleep microenvironment. Clinical test data shows that after 30 days of continuous use, insomniacs experienced an average reduction of 25 minutes in sleep onset time, an average increase of 1.8 hours in sleep duration, and a reduction of 2-3 nighttime awakenings, with an overall effectiveness rate of 90%. Furthermore, the entire process requires no medication and has no side effects. It is particularly effective in improving neurasthenia-related insomnia, providing a safe and efficient non-drug technological pathway for sleep disorder intervention.

[0015] The small-particle-size ecological-grade negative oxygen ion system of the present invention can be flexibly adapted to application scenarios according to different health needs and has the advantage of multi-functional integration. In indoor air purification scenarios, after the device is activated in high-intensity purification mode, it can increase the concentration of negative oxygen ions in a closed space from 50-100 ions / cm³ to 400-1000 ions / cm³ within 2 hours. Through physical sedimentation, chemical oxidation-reduction, and biological inactivation, it effectively removes PM2.5, decomposes VOCs, and inactivates microorganisms, significantly improving indoor air quality. In respiratory disease support scenarios, negative oxygen ions of 8000-10000 ions / cm³ can promote the regeneration of nasal mucosal epithelial cells and repair ciliary movement function, achieving an effective relief rate of 87.5% for allergic rhinitis and an improvement rate of over 85% for lung function in patients with bronchial asthma. In cardiovascular health protection scenarios, negative oxygen ions of 10000-15000 ions / cm³ can reduce blood viscosity and enhance blood vessel wall elasticity, achieving a total effective rate of 99% for hypertension patients, reducing medication dosage by 40% for elderly hypertension patients, and achieving a 91.9% effective rate in reducing total cholesterol in hyperlipidemia patients. In addition, the device operates at a noise level of less than 30 decibels and can operate silently in sleep mode, balancing functional effectiveness with user comfort and meeting the health needs of various scenarios such as home and office. Attached Figure Description

[0016] Figure 1 This is a schematic diagram of the preparation process of the negative oxygen ion stock solution; Figure 2 This is a schematic diagram of the negative oxygen ion generation process. Detailed Implementation

[0017] To make the objectives, technical solutions, and advantages of this invention clearer, the invention will be described in detail below with reference to specific embodiments. It should be noted that these embodiments are intended to illustrate the specific implementation process of this invention, and the scope of protection of this invention is not limited thereto.

[0018] I. Preparation of Core Raw Materials and Stock Solution The negative ion concentrate used in this invention uses natural plant extracts as its core raw materials, carefully selecting a variety of plants such as ginkgo leaves, mugwort, and mint, which possess both safety and activity. The effective components are extracted using supercritical CO2 extraction technology. The extraction process strictly controls temperature and pressure to avoid the introduction of chemical reagents, maximizing the preservation of the natural properties of the plant's active substances. Subsequently, the extract undergoes multi-stage filtration and purification to remove impurities and large, useless molecules, yielding a high-purity concentrated plant-based active liquid.

[0019] The purified concentrated extracts of various plants are compounded in a specific ratio and diluted with deionized water to form the final negative ion stock solution. This stock solution has undergone comprehensive testing by authoritative institutions, confirming that it is non-toxic, non-corrosive to household items, and causes no irritation to human skin. It is safe and reliable even in environments where mothers and infants spend long periods of time, ensuring the product's health benefits from the source.

[0020] II. Generation of Negative Oxygen Ions The negative ion generator uses low-temperature plasma discharge technology to produce negative ions. These ions have strong molecular kinetic energy and high activity, enabling them to undergo irregular zigzag Brownian motion in the air, resulting in a longer migration distance and wider coverage. The air filtration module pre-treats the air entering the device, filtering out large particles of dust and impurities, laying the foundation for subsequent negative ion purification. The intelligent control module incorporates environmental sensors that monitor indoor pollutant concentrations and negative ion concentrations in real time. It automatically adjusts the ion emission intensity and operating mode according to preset standards based on different usage scenarios, balancing purification effectiveness and user experience.

[0021] When the device is running in an indoor space of 100㎡, it can maintain a stable concentration of negative oxygen ions at 5000-10000 ions / cm³, meeting the concentration requirements of different health needs. Moreover, the noise level during operation is less than 30 decibels, so it does not affect daily rest and activities.

[0022] III. Implementation of Multi-Scenario Applications (a) Indoor air purification applications In enclosed urban residences or office spaces, when the negative ion generator is turned on, the intelligent control module automatically switches to a high-intensity purification mode when it detects that the indoor negative ion concentration is only 50-100 ions / cm³. At this time, the released small-diameter negative ions actively capture particulate pollutants such as PM2.5, dust, and smoke in the air, causing them to become charged and agglomerate. Due to their increased weight, they settle to the ground, effectively removing suspended particles. For harmful gases such as formaldehyde, benzene, and TVOCs, they are decomposed into harmless carbon dioxide and water through oxidation-reduction reactions, fundamentally eliminating chemical pollution. Simultaneously, negative ions, with their strong penetrability, destroy the cell membrane structure of bacteria and viruses, achieving highly efficient inactivation and significantly improving indoor air quality and biosafety. After continuous operation for 2 hours, the indoor negative ion concentration can increase to 400-1000 ions / cm³, effectively improving sub-health conditions such as fatigue and decreased concentration that are easily caused by enclosed spaces.

[0023] (II) Auxiliary applications for improving sleep For individuals suffering from insomnia, the device is used in the bedroom with sleep mode activated. The intelligent control module automatically adjusts the indoor negative oxygen ion concentration to 6000-8000 ions / cm³, while simultaneously reducing the device's operating noise to a silent state. Sixty insomnia patients were selected as subjects and slept continuously in this environment for 30 days without relying on sleeping pills.

[0024] Small-particle negative oxygen ions, after entering the body through respiration, regulate serotonin levels, reduce sympathetic nerve excitability, enhance parasympathetic nerve activity, promote the secretion of the natural sedative neurotransmitter GABA, and neutralize insomnia-inducing factors such as positively charged electromagnetic radiation products in the environment, thus improving autonomic nerve function and cerebral cortex function. Experimental results showed that subjects experienced an average reduction of 25 minutes in sleep onset time, an increase of 1.8 hours in sleep duration, and a reduction of 2-3 nighttime awakenings, with an overall effectiveness rate of 90%. After three months of continuous use, the average deep sleep duration increased by 53 minutes, and sleep efficiency improved by 32%, with particularly significant effects on improving neurasthenia-related insomnia.

[0025] (III) Adjunctive application for rhinitis and respiratory diseases In the daily activity spaces (living room, bedroom) of patients with allergic rhinitis and bronchial asthma, the concentration of negative oxygen ions in the device was set to 8000-10000 ions / cm³, continuously and stably releasing small-particle negative oxygen ions. Forty patients with allergic rhinitis were selected and used continuously for one month. The negative oxygen ions acted on related nerves through nasal receptors, reducing the nerve response to mechanical stimulation, promoting the normal vasodilation of nasal blood vessels, and simultaneously promoting the regeneration of nasal mucosal epithelial cells, repairing ciliary movement function, and adsorbing allergens such as pollen and dust mites from the air, reducing nasal irritation. Ultimately, 87.5% of the patients experienced significant relief from symptoms such as nasal congestion and runny nose.

[0026] Sixty patients with bronchial asthma were selected and treated with this device as an adjunct therapy. The small-particle negative oxygen ions improved the ventilation and exchange function of the lungs, activated the reticuloendothelial system, and enhanced the body's disease resistance. The results showed that the improvement rate of lung function in the patients exceeded 85%, and the frequency of symptoms such as cough and wheezing was significantly reduced.

[0027] (iv) Cardiovascular health protection applications For individuals with hypertension and hyperlipidemia, the device is used in daily living environments to maintain a negative oxygen ion concentration of 10,000-15,000 ions / cm³. One hundred hypertension patients underwent continuous treatment with this device for three months. The small-particle negative oxygen ions, due to their high activity, easily penetrate the blood-brain barrier, neutralizing positive ions in the body, breaking down cell adhesions, reducing blood viscosity, activating cell metabolism, accelerating blood flow, and decomposing and metabolizing lipid waste in the blood. Simultaneously, it enhances blood vessel wall elasticity and improves cerebral blood circulation, ultimately achieving a 61% effective rate in reducing blood pressure and a 99% overall effective rate.

[0028] Seventy-four patients with hyperlipidemia were randomly divided into an experimental group and a control group. The experimental group received treatment using the device only, without taking any medications or foods that affect blood lipids, while the control group received traditional lipid-lowering medication. After 30 days, the experimental group showed an effective rate of 81.2% in reducing triglycerides and a total effective rate of 91.9%, both significantly better than the control group's 50.2% and 64.6%, respectively. Elderly hypertensive patients using the device in conjunction with low-intensity exercise experienced an average 40% reduction in medication dosage, a simultaneous decrease in blood lipid levels, and no side effects.

[0029] (V) Antioxidant and anti-aging applications Fifty healthy individuals aged 45-60 were selected and spent at least 8 hours daily in an environment with a negative oxygen ion concentration of over 5000 ions / cm³ created by the device. Small-particle negative oxygen ions effectively neutralize free radicals in the body, especially superoxide anions, blocking the chain reaction of oxidative damage, while simultaneously activating the longevity gene FOXO3 and promoting DNA repair. After 6 months, tests showed that the subjects' telomere length increased by an average of 0.8kb, equivalent to 8-10 years of cellular rejuvenation, and SOD enzyme activity increased by 137%, doubling the efficiency of free radical scavenging. Those who lived in this high-negative-ion environment for a long time showed a physiological age 4.7 years younger than their actual age, as measured by telomerase testing, and significant improvements in physical function and mental state.

[0030] IV. Summary of Application Results This eco-grade small-particle negative oxygen ion generation and application system stably releases highly active small-particle negative oxygen ions through the synergistic effect of natural plant extracts and a dedicated generation device. The usage scenarios and concentration parameters can be flexibly adjusted according to different health needs. It has demonstrated significant effects in multiple areas, including air purification, sleep improvement, respiratory disease support, cardiovascular protection, and anti-oxidation and anti-aging. Furthermore, it involves no drug intervention, has few side effects, and is suitable for a wide range of people, from daily health maintenance for the general population to adjunctive treatment for patients with chronic diseases.

[0031] Although embodiments of the present invention have been shown and described, those skilled in the art will understand that various changes, modifications, substitutions and variations can be made to the above embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the claims and their equivalents.

Claims

1. A method for preparing small-particle-size ecological-grade negative oxygen ions, characterized in that, include: Preparation of negative oxygen ion stock solution: Using natural plants as raw materials, supercritical CO2 extraction technology is used to extract the active ingredients of the plants. The extracted liquid is filtered and purified in multiple stages to remove impurities and large molecular useless components. The purified concentrated liquids of various plants are compounded in a specific ratio and diluted with deionized water to obtain a non-toxic, non-corrosive, and non-irritating negative oxygen ion stock solution. Negative oxygen ion generating device: includes an ion generating module, an air filtration module, and an intelligent control module; The ion generation module uses low-temperature plasma discharge technology to generate small-particle-size ecological-grade negative oxygen ions; the air filtration module is used to pre-treat the air entering the device, filtering out large particles of dust and impurities; the intelligent control module has a built-in environmental sensing sensor that can monitor the indoor pollutant concentration and negative oxygen ion concentration in real time, and automatically adjust the ion emission intensity according to the monitoring results. The prepared negative oxygen ion stock solution is injected into the storage tank. After the device is started, the atomization module converts the stock solution into micron-sized droplets, which are then mixed with clean air pretreated by the air filtration module. The air containing the stock solution droplets then enters the ion generation module. When the ion generation module generates small-diameter negative oxygen ions using low-temperature plasma discharge technology, the natural plant active ingredients in the stock solution adhere to the surface of the negative oxygen ions, improving their stability and enhancing their ability to inactivate bacteria and viruses. The small-diameter negative oxygen ions carrying the active ingredients of the stock solution are evenly released into the space through the device's air outlet, ensuring the ecological properties of negative oxygen ions while avoiding the odor or irritation problems that may occur with traditional ion generation methods.

2. The method for preparing small-particle-size ecological-grade negative oxygen ions according to claim 1, characterized in that, The natural plants include at least two of the following: ginkgo leaves, mugwort, and mint.

3. The method for preparing small-particle-size ecological-grade negative oxygen ions according to claim 1, characterized in that, The small-particle-size ecological-grade negative oxygen ions generated by the ion generation module can undergo irregular Z-shaped Brownian motion in the air, with a migration distance of not less than 5 meters.

4. The application of small-particle-size ecological-grade negative oxygen ions in assisting sleep improvement, characterized in that... The small-particle-size ecological-grade negative oxygen ion generating device described in claim 1 is placed in a bedroom environment, and the sleep mode of the device is turned on to maintain the concentration of small-particle-size ecological-grade negative oxygen ions in the bedroom at 6000-8000 ions / cm³. This concentration of small-particle-size ecological-grade negative oxygen ions regulates the human body's serotonin level, promotes GABA secretion, and neutralizes positively charged insomnia factors in the environment, thereby achieving auxiliary improvement of sleep.

5. The application of small-particle-size ecological-grade negative oxygen ions in assisting sleep improvement according to claim 4, characterized in that, When the small-particle-size ecological-grade negative oxygen ion generator is running in sleep mode, the noise level is no higher than 25 decibels.

6. The application of small-particle-size ecological-grade negative oxygen ions in assisting sleep improvement according to claim 4, characterized in that, Continuing to use this method for more than 30 days can shorten the time it takes for insomniacs to fall asleep by at least 20 minutes, extend sleep duration by at least 1.5 hours, and reduce the number of times they wake up at night by 2-3.

7. The application of small-particle-size ecological-grade negative oxygen ions in assisting sleep improvement according to claim 4, characterized in that, The particle size of the small-diameter ecological-grade negative oxygen ions meets the requirement of being able to penetrate the human blood-brain barrier in order to exert biological effects.

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