Vacuum tabletting method of superfine ganoderma lucidum spore powder

Abstract

The superfine ganoderma lucidum spore powder belongs to powder with large specific surface area, extremely low bulk density, poor flowability and large air suction amount, so that the filling of a tabletting mold and the compression molding of tablets cannot be completed or are extremely difficult to complete under the atmospheric condition; according to the tabletting method of the superfine ganoderma lucidum spore powder, the processes of tabletting mold filling and tablet compression molding are all carried out under the vacuum condition, that is, the whole, except for a motor and a speed reducer, of a tabletting machine is placed in a bell jar vacuum tank, and all mechanical operations of the tabletting machine are carried out under the vacuum condition; the superfine ganoderma lucidum spore powder does not float in vacuum under the vacuum condition, the superfine ganoderma lucidum spore powder has enough fluidity, the mechanism is that the fluidity of the superfine ganoderma lucidum spore powder is reduced by air suspension force and air viscous force under the atmospheric condition, and the superfine ganoderma lucidum spore powder can be filled into a tabletting mold in a gravity feeding mode under the vacuum condition; under a vacuum condition, gas adsorption of large specific surface area of the superfine ganoderma lucidum spore powder and gas adsorption in ganoderma lucidum spore powder particles are desorbed, so that the technical problem that the superfine ganoderma lucidum spore powder cannot be completely exhausted and formed in a pressing process under an atmospheric condition is solved; the single and pure superfine ganoderma lucidum spore powder can be subjected to vacuum tabletting to form the single and pure superfine ganoderma lucidum spore powder tablet without adding auxiliaries for granulation.

Description

Technical Field

[0001] A vacuum compression method for ultrafine Ganoderma lucidum spore powder is disclosed, relating to the manufacturing methods of pharmaceuticals and health products. Background Technology

[0002] Ultrafine Ganoderma lucidum spore powder is a health supplement. Currently, Ganoderma lucidum spore powder is available in powder form, which is less convenient than tablets and has a bitter taste. The extremely large specific surface area of ​​ultrafine Ganoderma lucidum spore powder results in a large amount of gas adsorbed on its surface and within the particles, extremely low bulk density, low specific gravity, and extremely small average particle size. This makes it impossible to compress pure, ultrafine Ganoderma lucidum spore powder into tablets using ordinary tableting machines under atmospheric conditions. The mechanism is: 1. Ultrafine Ganoderma lucidum spore powder with extremely low bulk density, low specific gravity, and extremely small average particle size easily floats in the air, similar to PM5 and PM2.5 dust. 1. Because dust floats in the air and does not easily settle, ultrafine Ganoderma lucidum spore powder cannot be automatically filled into the tableting mold by gravity under atmospheric conditions. 2. The huge specific surface area of ​​ultrafine Ganoderma lucidum spore powder results in a large amount of gas adsorbed on its surface and inside the particles. The tableting process must completely expel the adsorbed gas from the ultrafine Ganoderma lucidum spore powder before tablets can be formed. Due to the small gap of the mold suitable for tableting, it is impossible to completely expel the adsorbed gas from the ultrafine Ganoderma lucidum spore powder during the tableting process. The adsorbed gas is compressed inside the tablet, and the expansion of the compressed gas after demolding causes the tablet to disintegrate.

[0003] This invention discloses a vacuum tableting method for ultrafine Ganoderma lucidum spore powder. The tableting mechanism, excluding the motor and reducer, is placed inside a liftable, vacuum-sealed bell-shaped container. All mechanical operations of the tableting machine are performed under vacuum conditions. Under vacuum conditions, the ultrafine Ganoderma lucidum spore powder will not float in the vacuum, allowing for gravity-feeding of the ultrafine Ganoderma lucidum spore powder into the tableting mold. Vacuum conditions desorb the gas adsorption due to the large specific surface area of ​​the ultrafine Ganoderma lucidum spore powder and the gas adsorption within the Ganoderma lucidum spore powder particles, thus solving the technical problem of not being able to expel gas and form the powder during the compression process under atmospheric conditions. This allows pure ultrafine Ganoderma lucidum spore powder to be vacuum-compressed into tablets without the need for additives or granulation. Summary of the Invention

[0004] A vacuum tableting method for ultrafine Ganoderma lucidum spore powder involves conducting the entire tableting process—including filling the tableting mold and pressing into tablets—under vacuum conditions. Specifically, the tableting machinery, excluding the motor and reducer, is placed inside a liftable, vacuum-sealed bell-shaped container. A sealing ring forms a vacuum-sealed space between the bottom circumferential flange of the bell-shaped container and the upper surface of the base plate housing the motor and reducer. A sealing ring also seals the main shaft and the base plate, and the vacuum port is located on the base plate. All mechanical operations of the tableting machine are performed under vacuum conditions. Under vacuum, the ultrafine Ganoderma lucidum spore powder will not float in the vacuum, ensuring sufficient flow. The mechanism of this process is that the air suspension force and air viscosity under atmospheric conditions reduce the fluidity of ultrafine Ganoderma lucidum spore powder. Under vacuum conditions, ultrafine Ganoderma lucidum spore powder can be filled into the tableting mold by gravity feeding, just like a feather and an iron ball have the same free fall speed under vacuum conditions. Under vacuum conditions, the gas adsorption of the large specific surface area of ​​ultrafine Ganoderma lucidum spore powder and the gas adsorption within the Ganoderma lucidum spore powder particles are desorbed, thus solving the technical problem that the ultrafine Ganoderma lucidum spore powder cannot be completely degassed and formed during the pressing process under atmospheric conditions. This allows pure ultrafine Ganoderma lucidum spore powder to be vacuum-compressed into pure ultrafine Ganoderma lucidum spore powder tablets without the need for the addition of auxiliary granulation agents.

[0005] The vacuum condition is a pressure ≤500Pa, which can effectively prevent dust explosions of organic powders such as ultrafine Ganoderma lucidum spore powder.

[0006] The feeding system of the tablet press is placed in a vacuum-sealed bell jar. The vacuum is removed and the bell jar is raised to load the tablets.

[0007] The tablet storage system of the tablet press is placed in a vacuum-sealed bell jar. The tablets can be removed by removing the vacuum and raising the bell jar. Specific implementation methods

[0008] Vacuum tablet press preparation: The entire process of filling the tableting mold and pressing into tablets is carried out under vacuum conditions. That is, the tableting mechanical mechanism of the tablet press, except for the motor and reducer, is placed in a liftable, vacuum-sealed bell jar. The bottom circumferential flange plane of the bell jar is sealed with a sealing ring between the bottom circumferential flange plane and the upper plane of the base plate on which the motor and reducer are installed, forming a vacuum-sealed space. The main shaft is sealed with a sealing ring between it and the base plate. The vacuum port is placed on the base plate. All mechanical operations of the tablet press are carried out under vacuum conditions.

[0009] Raise the bell cover and load the ultrafine Ganoderma lucidum spore powder into the loading hopper of the automatic feeding system of the vacuum tablet press. Lower the bell cover to seal it.

[0010] Start the vacuum pump and evacuate the bell jar to a pressure below 500 Pa.

[0011] Start the vacuum tablet press and begin the tableting operation. Once the powder in the loading hopper is used up, turn off the vacuum pump.

[0012] Remove the vacuum bell jar, take out the ultrafine tablets, reload, and repeat the above operation to restart tableting.

Claims

1. A vacuum tableting method for ultrafine Ganoderma lucidum spore powder, characterized by: the entire process of filling the tableting mold and pressing into tablets is carried out under vacuum conditions; that is, the tableting mechanical mechanism of the tableting machine, except for the motor and reducer, is placed inside a hydraulically driven, liftable, and vacuum-sealed bell-shaped container; a sealing ring is formed between the bottom circumferential flange plane of the bell-shaped container and the upper plane of the base plate on which the motor and reducer are installed, creating a vacuum-sealed space; a sealing ring is also formed between the main shaft and the base plate; the vacuum port is located on the base plate; all mechanical operations of the tableting machine are performed under vacuum conditions; under vacuum conditions, the ultrafine Ganoderma lucidum spore powder will not float. Floating in a vacuum, ultrafine Ganoderma lucidum spore powder exhibits sufficient fluidity. The mechanism is that the air suspension force and air viscosity under atmospheric conditions reduce the fluidity of ultrafine Ganoderma lucidum spore powder. Under vacuum conditions, ultrafine Ganoderma lucidum spore powder can be filled into the tableting mold by gravity feeding. Under vacuum conditions, the gas adsorption of the large specific surface area of ​​ultrafine Ganoderma lucidum spore powder and the gas adsorption within the Ganoderma lucidum spore powder particles are desorbed, thus solving the technical problem that ultrafine Ganoderma lucidum spore powder cannot be completely degassed and formed during the pressing process under atmospheric conditions. This allows pure ultrafine Ganoderma lucidum spore powder to be vacuum-compressed into pure ultrafine Ganoderma lucidum spore powder tablets without the need for the addition of auxiliary granulation agents.

2. According to claim 1, the vacuum condition is a pressure ≤ 500 Pa, which effectively prevents dust explosions of organic powders such as ultrafine Ganoderma lucidum spore powder.

3. According to claim 1, the feeding system of the tablet press is placed in a vacuum-sealed bell jar, and the material can be loaded by removing the vacuum and raising the bell jar.

4. According to claim 1, the tablet storage system of the tablet press is placed in a vacuum-sealed bell jar, and the tablets can be removed by removing the vacuum and raising the bell jar.

5. A vacuum compression method for ultrafine Ganoderma lucidum spore powder, applicable to the vacuum compression forming of ultrafine plant powder, traditional Chinese medicine powder and other organic powders.