Remote monitoring system and method for in-vitro liver perfusion equipment

Abstract

According to the remote monitoring system and method for the in-vitro liver perfusion equipment, medical staff can move and operate a tablet personal computer within a certain range in an operating room without constraint of the physical position of an equipment host, a patient and the equipment can be taken into consideration at the same time, it can be guaranteed that the equipment is normally controlled in a small space or in a multi-person operation scene, and the operation efficiency is improved. The flexibility of the working process is improved; through the Internet cloud, remote specialists can observe the whole perfusion process in real time as if they are personally on site, so that instant remote guidance is provided for evaluation of marginal donor liver and processing of complex conditions, and the utilization efficiency and the treatment level of medical resources are improved; the dual network architecture provides communication redundancy to a certain extent. Based on the alarm pushing function of the cloud platform, 7 * 24-hour state monitoring is realized, even if field personnel leave temporarily, key alarms can be known in time through mobile phones, and the safety is greatly improved.

Description

Technical Field

[0001] This invention relates to the fields of extracorporeal circulation support and medical device control technology, and in particular to a remote monitoring system and method for an ex vivo liver perfusion device. Background Technology

[0002] Ex vivo liver perfusion devices can preserve, repair, and evaluate donor livers in vitro before organ transplantation. Currently, the control and monitoring systems for these devices often have the following limitations: 1. Limited and inconvenient control methods: Most devices rely on built-in embedded touch screens or physical buttons for operation, control, and data viewing. Medical staff need to be on duty next to the device at all times, and the operating space is limited, making it inconvenient to multitask in complex operating room environments.

[0003] 2. Data isolation, lack of collaboration and in-depth utilization: Equipment operation data is usually stored only locally on the device or connected to a single monitoring station via limited cables. Data cannot be easily synchronized to the cloud or hospital information systems, resulting in difficulties such as remote experts being unable to conduct real-time consultations, difficulties in historical data analysis, lack of real-time linkage early warning and remote push, and insufficient network connection reliability. Summary of the Invention

[0004] To achieve the above-mentioned objectives and other advantages of the present invention, a first objective of the present invention is to provide a remote monitoring system for an ex vivo liver perfusion device, comprising: The main unit of the infusion equipment includes an execution unit for performing infusion operations, a sensor unit for collecting infusion parameter data, and a first wireless communication module; The control terminal has a second wireless communication module, a third wireless communication module, and a processor; The second wireless communication module is used to establish a private local area network connection with the first wireless communication module of the infusion equipment host to form a first communication link, so that the control terminal can perform real-time operation control and data monitoring of the infusion equipment host through the first communication link; The third wireless communication module is used to access the public Internet and form a second communication link; The processor is configured to execute a program as a data gateway: receiving raw data from the infusion device host and uploading processed monitoring data to a cloud server via the second communication link; A cloud server, deployed on the public Internet, is used to receive and store monitoring data from the control terminal and provide a remote access interface; A remote data receiving terminal is used to access the cloud server via the Internet to remotely view the operating status of the infusion device host.

[0005] Furthermore, the private local area network connection is a point-to-point Wi-Fi connection, with the infusion device host acting as a wireless access point and the control terminal acting as a station connected to this access point.

[0006] Furthermore, the communication data carried by the first communication link is encrypted using a first encryption protocol; the data transmitted between the control terminal and the cloud server through the second communication link is encrypted using a second encryption protocol.

[0007] Furthermore, the control terminal is a medical-grade tablet computer, which runs dedicated control software to achieve the following functions: The system receives user operation instructions through a graphical user interface and sends the operation instructions to the infusion device host through the first communication link. The sensor data and device status from the host of the infusion device are received and displayed in real time through the first communication link; The sensor data and at least a portion of the device status are encapsulated into the monitoring data and uploaded to the cloud server via the second communication link.

[0008] Furthermore, the control terminal is configured to require user account password or biometric authentication before operating or monitoring the main unit of the infusion device.

[0009] Furthermore, the cloud server is configured as follows: Provide the remote access interface in the form of a webpage or application; The monitoring data is analyzed according to preset early warning rules, and alarm information is generated and pushed to the designated remote data receiving terminal when the conditions are met; It can simultaneously receive and securely store data uploaded from multiple control terminals.

[0010] Furthermore, the processor of the control terminal is configured to: while performing real-time control and monitoring through the first communication link, simultaneously perform data upload to the cloud server in the background through the second communication link.

[0011] Furthermore, the third wireless communication module is a cellular mobile network module or a Wi-Fi network module; when the cellular mobile network signal is unstable, the control terminal can switch to connecting to an external Internet hotspot through an external or built-in Wi-Fi network module to maintain the second communication link.

[0012] A second objective of this invention is to provide a remote monitoring method for an ex vivo liver perfusion device, applied to a control terminal of a system as described above, the method comprising: Establish a private local area network connection with the main unit of the infusion equipment to form the first communication link; Through the first communication link, control commands are sent to the host of the infusion device, and the real-time sensor data and device status are received. Connect to the public internet to form a second communication link; Process at least a portion of the sensor data and device status into monitoring data; The monitoring data is uploaded to a cloud server via the second communication link, so that remote users can access the cloud server via the Internet to view the monitoring data.

[0013] Furthermore, before sending control commands to the infusion device host via the first communication link, the method further includes: verifying the user's operating permissions.

[0014] Compared with the prior art, the beneficial effects of the present invention are: This invention improves ease of operation and flexibility: medical staff can move and operate the tablet computer within a certain range in the operating room, freeing them from the physical constraints of the main unit. This allows them to simultaneously attend to both patients and the equipment, and also ensures normal control of the equipment in small spaces or multi-person operation scenarios, thus improving the flexibility of the workflow.

[0015] This invention enables true remote expert support and collaboration: through the internet cloud, senior experts in different locations can observe the entire perfusion process in real time as if they were on-site, providing immediate remote guidance for the assessment of marginal liver donors and the handling of complex situations, thereby improving the efficiency of medical resource utilization and the level of treatment.

[0016] This invention improves system reliability and early warning capabilities: the dual-network architecture (LAN + Internet) provides communication redundancy to a certain extent. Based on the cloud platform's alarm push function, 24 / 7 status monitoring is achieved, allowing personnel to receive timely critical alerts via mobile phone even when temporarily away from the site, greatly enhancing security.

[0017] This invention facilitates equipment management and maintenance: equipment manufacturers can remotely view equipment operating status and logs through authorization, perform fault pre-diagnosis and remote maintenance guidance, shorten repair time, and improve equipment utilization efficiency.

[0018] This invention enhances the digitalization and informatization of medical procedures: This solution seamlessly integrates the critical step of ex vivo perfusion into the medical Internet of Things, providing an important data node for the information management of smart operating rooms and transplant centers.

[0019] The above description is merely an overview of the technical solution of the present invention. In order to better understand the technical means of the present invention and to implement it according to the contents of the specification, the preferred embodiments of the present invention are described in detail below with reference to the accompanying drawings. Specific embodiments of the present invention are given in detail below with reference to the accompanying drawings. Attached Figure Description

[0020] The accompanying drawings, which are included to provide a further understanding of the invention and form part of this application, illustrate exemplary embodiments of the invention and, together with their description, serve to explain the invention and do not constitute an undue limitation thereof. In the drawings: Figure 1 A block diagram of a remote monitoring system for an ex vivo liver perfusion device; Figure 2 This is a schematic diagram of a remote monitoring system for an ex vivo liver perfusion device. Figure 3 This is a flowchart of a remote monitoring method for an ex vivo liver perfusion device. Detailed Implementation

[0021] The present invention will now be further described with reference to the accompanying drawings and specific embodiments. Obviously, the described embodiments are only a part of the embodiments of the present invention, and not all of them. It should be noted that, without conflict, the various embodiments or technical features described below can be arbitrarily combined to form new embodiments.

[0022] Based on the embodiments of this invention, all other embodiments obtained by those skilled in the art without inventive effort are within the scope of protection of this invention.

[0023] The drawing numbers in this application are only used to distinguish the steps in the scheme and are not used to limit the execution order of the steps. The specific execution order is as described in the specification.

[0024] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention pertains. The terminology used herein in the description of the invention is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention.

[0025] This invention provides a safe, reliable, convenient remote monitoring system for ex vivo liver perfusion equipment with powerful data interaction capabilities. The invention constructs a dual-network architecture combining "local area network near-end wireless control" and "Internet cloud-based remote monitoring."

[0026] Example 1 A remote monitoring system for ex vivo liver perfusion equipment, such as Figure 1 As shown, it includes: The main unit of the infusion equipment includes an execution unit for performing infusion operations, a sensor unit for collecting infusion parameter data, and a first wireless communication module; The control terminal has a second wireless communication module, a third wireless communication module, and a processor; The second wireless communication module is used to establish a private local area network connection with the first wireless communication module of the infusion equipment host to form a first communication link, so that the control terminal can perform real-time operation control and data monitoring of the infusion equipment host through the first communication link; The third wireless communication module is used to access the public Internet and form a second communication link; The processor is configured to execute a program as a data gateway: receiving raw data from the infusion device host and uploading processed monitoring data to a cloud server via the second communication link; A cloud server, deployed on the public Internet, is used to receive and store monitoring data from the control terminal and provide a remote access interface; A remote data receiving terminal is used to access the cloud server via the Internet to remotely view the operating status of the infusion equipment host. Specifically, authorized users can log in to the platform through any Internet-connected computer or mobile terminal to view the current operating status, historical operating status, infusion parameter curves, alarm logs, etc. of a specified device in real time, realizing remote monitoring across regions.

[0027] In this embodiment, the ex vivo liver perfusion device host collects all sensor data and controls each execution unit. It is equipped with a WiFi module for data interaction with a medical-grade tablet computer control terminal. Furthermore, the private local area network connection is a point-to-point Wi-Fi connection, with the perfusion device host acting as a wireless access point and the control terminal acting as a station connected to this access point.

[0028] The communication data carried by the first communication link is encrypted using a first encryption protocol; the data transmitted between the control terminal and the cloud server through the second communication link is encrypted using a second encryption protocol.

[0029] The control terminal is a medical-grade tablet computer, serving as the core human-computer interaction and gateway device. It runs dedicated control software to achieve the following functions: The system receives user operation instructions through a graphical user interface and sends the operation instructions to the infusion device host through the first communication link. Specifically, the first communication link (WiFi / LAN): establishes a secure private LAN connection (point-to-point WiFi) with the device host via the built-in WiFi module. Through this link, the medical-grade tablet computer control terminal can realize real-time, low-latency wireless operation control of the device infusion device host (such as starting and stopping the pump, setting parameters) and high-frequency data monitoring (real-time refresh of device status and infusion parameters).

[0030] The sensor data and device status from the host of the infusion device are received and displayed in real time through the first communication link; The sensor data and at least a portion of the device status are encapsulated into the monitoring data and uploaded to the cloud server via the second communication link.

[0031] Specifically, the second communication link (mobile network / Internet): accesses the public Internet through a built-in cellular mobile network module (4G / 5G) or by connecting to an external Internet hotspot.

[0032] The control terminal is configured to require user account password or biometric authentication before operating or monitoring the main unit of the infusion device.

[0033] The cloud server is configured as follows: Provide the remote access interface in the form of a webpage or application; The monitoring data is analyzed according to preset early warning rules, and alarm information is generated and pushed to the designated remote data receiving terminal when the conditions are met. It can simultaneously receive and securely store data uploaded from multiple control terminals (i.e., medical-grade tablets).

[0034] The processor of the control terminal is configured to: while performing real-time control and monitoring through the first communication link, simultaneously upload data to the cloud server in the background through the second communication link.

[0035] In this embodiment, the data gateway and processing unit in the medical-grade tablet computer control terminal run dedicated control software within the tablet computer, enabling the acquisition of raw data from the device host and its preprocessing and encapsulation; the encryption and synchronization of device operating status, liver perfusion parameters, and alarm information to the cloud server via the Internet link; the provision of security mechanisms: local area network communication uses encryption protocols (such as WPA2 / WPA3, TLS); and the implementation of operation permission management: close-range control and data monitoring require account passwords or biometric verification.

[0036] In this embodiment, the cloud server platform is deployed on the Internet to realize data reception and storage functions: receiving and securely storing real-time and historical data uploaded from multiple tablet control terminals; realizing data visualization and access interfaces: classifying and processing the received data, and providing access interfaces via web pages or mobile APPs; providing advanced functions: enabling multi-center data aggregation, big data analysis, generating injection reports, setting remote early warning rules, and pushing alarm information to multiple specified mobile phone numbers or accounts; providing security mechanisms: data transmission between devices and the cloud, and between the cloud and end users is encrypted throughout (such as HTTPS / SSL); realizing operation permission management: remote monitoring, modification of cloud configuration parameters, and remote data receiving terminal APP configuration distribution require different levels of account passwords or biometric verification.

[0037] Specifically, the third wireless communication module is a cellular mobile network module or a Wi-Fi network module; when the cellular mobile network signal is unstable, the control terminal can switch to connecting to an external Internet hotspot through an external or built-in Wi-Fi network module to maintain the second communication link.

[0038] like Figure 2 As shown, the working principle of the remote monitoring system for the ex vivo liver perfusion device is as follows: Hardware connection: When the host of the ex vivo liver perfusion device is powered on, its built-in WiFi module creates an encrypted wireless access point (AP mode).

[0039] Healthcare workers use antibacterial medical tablets to search for and connect to the device's Wi-Fi network, establishing a stable local area network connection.

[0040] Proximal control and monitoring: Dedicated control software is launched on a medical tablet computer. The software establishes a Socket connection with the device host via a local area network (LAN). Medical staff can perform all device operations on the tablet software interface, such as setting target perfusion pressure and temperature, viewing real-time blood flow curves and blood gas results, etc. All commands are instantly sent to the device host for execution via the LAN, and sensor data is also fed back to the tablet interface in real time with extremely low latency, meeting clinical real-time requirements.

[0041] Cloud Synchronization and Remote Access: While the medical tablet computer is under main control via WiFi, its mobile network module automatically connects to the internet. The tablet software encrypts and uploads critical operational data (such as periodic snapshots, alarm events, and trend data) to the cloud server via the mobile network in the background. To save bandwidth, incremental uploads and compression strategies can be employed. Transplant specialists, department heads, or equipment support engineers located in other locations can access the real-time monitoring interface of the device by logging into the secure cloud platform website via a browser on their personal computers or using the mobile application software, after entering their authorized account and password. They can observe the entire perfusion process but cannot directly intervene or control it. When an alarm occurs, the cloud platform can simultaneously send push notifications to pre-set mobile apps for medical personnel.

[0042] In particular, when the indoor mobile network becomes unstable, the tablet's control software can alert the user and allow manual operation to connect to an external internet hotspot via the built-in or external network card, ensuring the normal operation of the remote monitoring function.

[0043] Example 2 A remote monitoring method for an ex vivo liver perfusion device is provided, applied to the control terminal of the system described above. For a detailed description of the system and control terminal, please refer to the corresponding description in the above system embodiments, which will not be repeated here. Figure 2 , Figure 3 As shown, the method includes: S100: Establish a private local area network connection with the main unit of the injection equipment to form the first communication link; Specifically, when the ex vivo liver perfusion device is powered on, its built-in WiFi module creates an encrypted wireless access point (AP mode). Medical staff use a sterile medical tablet to search for and connect to the device's WiFi network, establishing a stable local area network connection.

[0044] S200. Send control commands to the host of the infusion device through the first communication link, and receive the real-time sensor data and device status returned by the host. Specifically, dedicated control software is launched on a medical tablet computer. The software establishes a socket connection with the perfusion equipment host via a local area network. Medical staff can perform all equipment operations on the tablet software interface, such as setting target perfusion pressure and temperature, viewing real-time blood flow curves and blood gas results, etc. All instructions are instantly sent to the equipment host for execution via the local area network, and sensor data is also fed back to the tablet interface in real time with extremely low latency, meeting clinical real-time requirements.

[0045] In some embodiments, before sending control commands to the infusion device host via the first communication link, the method further includes: verifying the user's operating permissions.

[0046] S300, connects to the public Internet, forming a second communication link; S400: Process at least a portion of the sensor data and the device status into monitoring data; S500: The monitoring data is uploaded to the cloud server via the second communication link, so that remote users can access the cloud server via the Internet to view the monitoring data.

[0047] While the medical tablet computer is controlled via WiFi, its mobile network module automatically connects to the internet. The tablet software encrypts and uploads critical operational data (such as periodic snapshots, alarm events, and trend data) to the cloud server via the mobile network in the background. To save bandwidth, incremental uploads and compression strategies are employed. Transplant specialists, department heads, or equipment support engineers located in other areas can access the real-time monitoring interface of the device by logging into the secure cloud platform website via a browser on their personal computers or using the mobile application software, after entering their authorized account and password. They can observe the entire perfusion process but cannot directly intervene or control it. When an alarm is triggered, the cloud platform can simultaneously send push notifications to pre-set mobile apps for medical personnel.

[0048] In particular, when the indoor mobile network becomes unstable, the tablet's control software can alert the user and allow manual operation to connect to an external internet hotspot via the built-in or external network card, ensuring the normal operation of the remote monitoring function.

[0049] The number of devices and processing scale described herein are for the purpose of simplifying the description of the invention. Applications, modifications, and variations of the invention will be readily apparent to those skilled in the art.

[0050] Although embodiments of the present invention have been disclosed above, they are not limited to the applications listed in the specification and embodiments. They can be applied to various fields suitable for the present invention. For those skilled in the art, other modifications can be easily made. Therefore, without departing from the general concept defined by the claims and their equivalents, the present invention is not limited to the specific details and illustrations shown and described herein.

[0051] It should also be noted that the terms "comprising," "including," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such a process, method, article, or apparatus. Without further limitation, an element defined by the phrase "comprising one..." does not exclude the presence of other identical elements in the process, method, article, or apparatus that includes said element.

[0052] The above description is merely an embodiment of this specification and is not intended to limit the scope of one or more embodiments of this specification. Various modifications and variations can be made to one or more embodiments of this specification by those skilled in the art. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principle of one or more embodiments of this specification should be included within the scope of the claims of one or more embodiments of this specification.

Claims

1. A remote monitoring system for an extracorporeal liver perfusion apparatus, characterized in that, include: The main unit of the infusion equipment includes an execution unit for performing infusion operations, a sensor unit for collecting infusion parameter data, and a first wireless communication module; The control terminal has a second wireless communication module, a third wireless communication module, and a processor; The second wireless communication module is used to establish a private local area network connection with the first wireless communication module of the infusion equipment host to form a first communication link, so that the control terminal can perform real-time operation control and data monitoring of the infusion equipment host through the first communication link; The third wireless communication module is used to access the public Internet and form a second communication link; The processor is configured to execute a program as a data gateway: receiving raw data from the infusion device host and uploading processed monitoring data to a cloud server via the second communication link; A cloud server, deployed on the public Internet, is used to receive and store monitoring data from the control terminal and provide a remote access interface; A remote data receiving terminal is used to access the cloud server via the Internet to remotely view the operating status of the infusion device host.

2. A remote monitoring system for an extracorporeal liver perfusion apparatus as defined in claim 1, characterized in that The private local area network connection is a point-to-point Wi-Fi connection, with the infusion device host acting as a wireless access point and the control terminal acting as a station connected to this access point.

3. The remote monitoring system for an ex vivo liver perfusion device as described in claim 1, characterized in that, The communication data carried by the first communication link is encrypted using a first encryption protocol; the data transmitted between the control terminal and the cloud server through the second communication link is encrypted using a second encryption protocol.

4. The remote monitoring system for an ex vivo liver perfusion device as described in claim 1, characterized in that, The control terminal is a medical-grade tablet computer, which runs dedicated control software to achieve the following functions: The system receives user operation instructions through a graphical user interface and sends the operation instructions to the infusion device host through the first communication link. The sensor data and device status from the host of the infusion device are received and displayed in real time through the first communication link; The sensor data and at least a portion of the device status are encapsulated into the monitoring data and uploaded to the cloud server via the second communication link.

5. The remote monitoring system for an ex vivo liver perfusion device as described in claim 4, characterized in that, The control terminal is configured to require user account password or biometric authentication for operation permission before operating or monitoring the main unit of the infusion equipment.

6. The remote monitoring system for an ex vivo liver perfusion device as described in claim 1, characterized in that, The cloud server is configured as follows: Provide the remote access interface in the form of a webpage or application; The monitoring data is analyzed according to preset early warning rules, and alarm information is generated and pushed to the designated remote data receiving terminal when the conditions are met; It can simultaneously receive and securely store data uploaded from multiple control terminals.

7. The remote monitoring system for an ex vivo liver perfusion device as described in claim 1, characterized in that, The processor of the control terminal is configured to: while performing real-time control and monitoring through the first communication link, simultaneously upload data to the cloud server in the background through the second communication link.

8. The remote monitoring system for an ex vivo liver perfusion device as described in claim 1, characterized in that, The third wireless communication module is a cellular mobile network module or a Wi-Fi network module; when the cellular mobile network signal is unstable, the control terminal can switch to connecting to an external Internet hotspot through an external or built-in Wi-Fi network module to maintain the second communication link.

9. A remote monitoring method for an ex vivo liver perfusion device, characterized in that, The method, applied to a control terminal of the system as described in any one of claims 1 to 8, comprises: Establish a private local area network connection with the main unit of the injection equipment to form the first communication link; Through the first communication link, control commands are sent to the host of the infusion device, and the real-time sensor data and device status are received. Connect to the public internet to form a second communication link; Process at least a portion of the sensor data and device status into monitoring data; The monitoring data is uploaded to a cloud server via the second communication link, so that remote users can access the cloud server via the Internet to view the monitoring data.

10. A remote monitoring method for an ex vivo liver perfusion device as described in claim 9, characterized in that, Before sending control commands to the infusion device host via the first communication link, the method further includes: verifying the user's operating permissions.

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