Immunity-enhancing sea cucumber peptide solid beverage and production process thereof

Abstract

The invention relates to the technical field of health-care food, in particular to a sea cucumber peptide solid beverage capable of enhancing immunity and a production process of the sea cucumber peptide solid beverage. The sea cucumber peptide health-care food is prepared from the following raw materials: more than or equal to 50% of sea cucumber peptide, more than or equal to 10.55% of rhizoma polygonati powder, more than or equal to 5% of fructus lycii powder, more than or equal to 5% of mulberry powder, more than or equal to 4% of herba cistanche powder, more than or equal to 1% of eucommia male pollen, more than or equal to 1% of gynura procumbens powder, more than or equal to 1% of ginseng powder, more than or equal to 0.5% of maca powder and Through scientific compatibility of the sea cucumber peptide, the rhizoma polygonati, the herba cistanche and other components, the content of lactic acid and malondialdehyde can be reduced, the testosterone level of serum and the sperm quality can be remarkably improved, deep synergy of fatigue resistance, oxidation resistance and improvement of male physiological indexes is achieved, the small molecule characteristic that the high-content sea cucumber peptide is easily absorbed by intestinal tracts is utilized, and the health care effect is achieved. And in cooperation with protein and rich B vitamins and minerals, the quick conversion requirement of organisms on high-concentration nutrients is effectively met.

Description

Technical Field

[0001] This invention relates to the field of health food technology, specifically to a sea cucumber peptide solid beverage that enhances immunity and its production process. Background Technology

[0002] With the fast pace of life, men are often subjected to high-intensity work pressure and unhealthy lifestyles, which can easily lead to decreased immunity and sub-health problems. Studies have shown that fatigue, exhaustive exercise and psychological stress are often accompanied by decreased serum testosterone, fluctuations in luteinizing hormone and increased sperm abnormality rate, which seriously affect men's quality of life and reproductive health. Strenuous exercise can also cause the accumulation of serum lactic acid and urea nitrogen and cause oxidative damage to the liver, manifested as elevated malondialdehyde.

[0003] Existing anti-fatigue or immune-boosting products generally have the following shortcomings: First, most are single extracts, making it difficult to achieve multiple effects such as anti-fatigue, anti-oxidation, and reproductive system regulation; second, the absorption rate of large molecular proteins and active ingredients in traditional dietary supplements is low, making it difficult to quickly improve physiological indicators; and third, the lack of strict process control in the detection of minute foreign objects and the sterilization of inner packaging during the production process affects the long-term quality stability of solid beverages.

[0004] Therefore, developing a solid beverage with high content of sea cucumber peptides as the core, which can enhance immunity, fight fatigue, comprehensively improve male health indicators, and has high safety, as well as its production process, has become an urgent technical problem to be solved in this field. To solve the above problems, this application proposes a sea cucumber peptide solid beverage that enhances immunity and its production process. Summary of the Invention

[0005] To address the shortcomings of existing technologies, this invention provides a sea cucumber peptide solid beverage that enhances immunity and its production process, thus solving the problems mentioned in the background art.

[0006] The above-mentioned technical objective of the present invention is achieved through the following technical solution: A sea cucumber peptide solid beverage for enhancing immunity, by weight percentage, is composed of the following components: sea cucumber peptide ≥50%, Polygonatum sibiricum powder ≥10.55%, wolfberry powder ≥5%, mulberry powder ≥5%, Cistanche deserticola powder ≥4%, Eucommia ulmoides male flower powder ≥1%, Chrysanthemum indicum and Panax notoginseng powder ≥1%, ginseng powder ≥1%, maca powder ≥0.5%, with the remainder being auxiliary ingredients; The auxiliary ingredients include: orange juice powder, maltitol, calcium lactate, ginger powder, silicon dioxide, food processing yeast powder, and steviol glycosides.

[0007] Preferably, the nutritional composition of the sea cucumber peptide solid beverage meets the following requirements: per 100g of solid beverage, the protein content is 46.4g-47.1g, the calcium content is 748mg, the iron content is 25.9mg, and the zinc content is 1.04mg.

[0008] Preferably, the sea cucumber peptide solid beverage also contains a variety of B vitamins, specifically in the following amounts per 100g of solid beverage: pantothenic acid 7.47mg, vitamin B1 1.56mg, vitamin B2 1.78mg, nicotinamide 12942μg, and folic acid 361μg.

[0009] Preferably, the sea cucumber peptide solid beverage also contains dietary fiber and sugar, with 8.2g of dietary fiber and 12.5g of sugar per 100g of solid beverage.

[0010] The present invention also provides a production process for the above-mentioned sea cucumber peptide solid beverage, comprising the following steps: a) Raw material procurement and CCP1 raw material inspection: Obtain relevant certificates from suppliers. The purchased raw materials are subject to sensory inspection by the quality control department. They must have the inherent color and odor of the raw materials, and be free from mold, pests and other odors. After acceptance, they are put into storage. b) Procurement and handling of inner packaging materials: After the inner packaging materials are procured and inspected and approved, they are issued for use, unpacked and then sent to the disinfection room for CCP3 disinfection. c) Raw material pretreatment: Raw and auxiliary materials are requisitioned according to production needs, unpacked, and screened. d) CCP2 Ingredients and Mixing: Accurately weigh each raw material component according to the formula ratio, and put the weighed materials into the mixer for thorough mixing to obtain a semi-finished product; e) Inner and outer packaging: The mixed semi-finished products are inner-packaged using the inner packaging material processed in step b), and then outer-packaged after the inner packaging is completed; f) CCP4 X-ray machine inspection: The finished product is inspected for foreign objects by an X-ray machine detector. After passing the inspection, the finished product is put into storage.

[0011] Furthermore, in step b), the inner packaging material is disinfected using ozone, and the ozone disinfection time is not less than 30 minutes.

[0012] Furthermore, in step f), the detection standard for the X-ray detector is: no metal, ceramic, or glass foreign objects are present in the finished product, wherein the parameters of the X-ray detector are set as follows: iron (FE) ≤ 1.0 mm, stainless steel (SUS) ≤ 2.0 mm, ceramic ≤ 3.0 mm, and glass ≤ 3.0 mm.

[0013] Furthermore, this invention also relates to the application of the aforementioned sea cucumber peptide solid beverage in the preparation of health foods or medicines with functions such as enhancing immunity, anti-fatigue, reducing serum lactate content, reducing liver malondialdehyde content, increasing serum testosterone levels, and reducing sperm malformation rate.

[0014] In summary, the present invention has the following main beneficial effects: 1. This invention, through the scientific combination of sea cucumber peptides with ingredients such as Polygonatum sibiricum and Cistanche deserticola, has been experimentally proven to reduce lactic acid and malondialdehyde content, and significantly improve serum testosterone levels and sperm quality. It achieves a deep synergistic effect of anti-fatigue, anti-oxidation and improvement of male physiological indicators, avoiding the problems of single ingredients and weak synergy in existing products.

[0015] 2. This invention utilizes the small molecule characteristics of high-content sea cucumber peptides that are easily absorbed by the intestines, combined with protein and abundant B vitamins and minerals. Through a formula with high bioavailability, the active ingredients can quickly enter the circulatory system, effectively meeting the body's need for rapid conversion of high-concentration nutrients.

[0016] 3. This invention improves the food safety and quality stability of the product from both biological and physical perspectives through the CCP1-CCP4 whole-process quality control system. Attached Figure Description

[0017] Figure 1 This is a schematic diagram of body weight and food intake in the embodiments; Figure 2 This is a schematic diagram of swimming to exhaustion in the embodiment; Figure 3 This is a schematic diagram of mating ability in the embodiment; Figure 4 This is a schematic diagram of fatigue indicators in the embodiment; Figure 5 This is a schematic diagram of hormone levels in the examples; Figure 6 This is a schematic diagram of the morphology of testicular and epididymal tissues in the embodiment; Figure 7 This is a schematic diagram of sperm abnormality rate in the embodiment. Detailed Implementation

[0018] To make the objectives, technical solutions, and advantages of the embodiments of the present invention clearer, the technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are some embodiments of the present invention, but not all embodiments. Based on the described embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0019] The following embodiments are used to illustrate the present invention, but should not be used to limit the scope of protection of the present invention. The conditions in the embodiments can be further adjusted according to specific conditions, and simple improvements to the method of the present invention under the premise of the concept of the present invention are all within the scope of protection claimed by the present invention.

[0020] Example 1

[0021] This embodiment provides a sea cucumber peptide solid beverage to enhance immunity. By weight percentage, its raw materials consist of the following components: 50.0% sea cucumber peptide, 10.55% Polygonatum sibiricum powder, 5.0% wolfberry powder, 5.0% mulberry powder, 4.0% Cistanche deserticola powder, 1.0% Eucommia ulmoides male flower powder, 1.0% Chrysanthemum indicum and Panax notoginseng powder, 1.0% ginseng powder, 0.5% maca powder, with the remainder being auxiliary raw materials. The auxiliary ingredients include: 10.0% orange juice powder, 8.95% maltitol, 1.0% calcium lactate, 1.0% ginger powder, 0.5% silicon dioxide, 0.4% food processing yeast powder, and 0.1% steviol glycosides.

[0022] Its production process includes the following steps: a) Raw material procurement and CCP1 raw material inspection: Obtain relevant certificates from suppliers. The purchased raw materials are subject to sensory inspection by the quality control department. They must have the inherent color and odor of the raw materials, and be free from mold, pests and other odors. After acceptance, they are put into storage. b) Procurement and handling of inner packaging materials: After the inner packaging materials are procured and inspected and approved, they are issued and unpacked. Then they are sent to the disinfection room for ozone disinfection in CCP3. The disinfection time is strictly controlled within 35 minutes to ensure that the microbial indicators of the inner packaging materials meet the standards. c) Raw material pretreatment: Raw and auxiliary materials are requisitioned according to the formula and unpacked. All powder raw materials are screened to remove large particles and clumps to ensure the fineness of the materials. d) CCP2 Ingredients and Mixing: Weigh each component according to the formula ratio using a high-precision electronic scale, and put them into a high-efficiency mixer one after another. Set the mixing time to 15-20 minutes to ensure that the sea cucumber peptides and the extracts of each Chinese herbal medicine are fully mixed to obtain a uniform semi-finished powder. e) Inner and outer packaging: In the cleanroom, automated filling (3g / packet) is carried out using packaging materials treated with CCP3, followed by sealing and outer box packaging; f) CCP4 X-ray machine inspection: Finished products undergo full inspection using a high-sensitivity X-ray machine detector. The rejection parameters for this step are set as follows: iron (FE) ≤ 1.0 mm, stainless steel (SUS) ≤ 2.0 mm, ceramics ≤ 3.0 mm, and glass ≤ 3.0 mm. Only products that pass the inspection can enter the finished product warehouse.

[0023] Example 2

[0024] The sea cucumber peptide solid beverage prepared in Example 1 was subjected to authoritative third-party testing, and the nutritional characteristics obtained are as follows: Protein and Energy: Each 100g of product contains 46.4g-47.1g of protein and 1518kJ / 324kcal of energy, classifying it as a high-protein, low-fat food.

[0025] Vitamin B complex (per 100g): Pantothenic acid 7.47mg, Vitamin B1 1.56mg, Vitamin B2 1.78mg, Nicotinamide 12942μg, Folic acid 361μg.

[0026] Trace elements (per 100g): Calcium content is 748mg, iron content is 25.9mg, and zinc content is 1.04mg.

[0027] Dietary fiber and sugar: The dietary fiber content is 8.2g, and the sugar content is 12.5g.

[0028] Example 3

[0029] I. Experimental Design Experimental protocol: SPF-grade male ICR mice were used, and the experiment was divided into three groups: Control group: Normal diet, no strenuous exercise, and gavage with an equal volume of saline solution; Model group: Normal diet, exhaustive exercise to establish model, and gavage with an equal volume of physiological saline; Product Group: Normal diet, exhaustive exercise modeling, daily gavage administration of sea cucumber peptide solid beverage prepared in Example 1.

[0030] II. Detection Indicators Body weight, food intake, exhaustive swimming, mating ability, fatigue index, hormone levels, testicular and epididymal tissue morphology, sperm morphology, and sperm abnormality rate.

[0031] III. Experimental Results 1. Regarding weight, food intake, and swimming to exhaustion, please refer to... Figures 1-2 As shown, the weight of mice in each group gradually increased with the increase of feeding time, but there was no statistical difference between the groups, indicating that the intake of the product did not affect the weight change of the mice; the amount of food consumed first increased and then tended to balance with exhaustive swimming training.

[0032] 3. Regarding mating ability, please refer to... Figure 3 As shown, compared with the blank group, the mating rate, number of captures, number of mountings and number of insertions in the model group were significantly reduced, indicating that exhaustive exercise can reduce sexual interest to some extent; compared with the model group, the product group significantly improved the mating ability of mice after acute exercise, including increasing the number of captures, number of ejaculations, number of mountings and number of insertions.

[0033] 4. Regarding fatigue indicators, please refer to... Figure 4As shown, compared with the blank group, the serum lactate and urea nitrogen levels in the model group were significantly increased, indicating that acute exhaustive swimming consumed a large amount of energy in mice and caused the accumulation of metabolites. In addition, acute exhaustive swimming caused an increase in malondialdehyde content in the liver of mice, indicating that the liver had undergone oxidative damage. Compared with the model group, the product group significantly reduced serum lactate and malondialdehyde content in the liver (p<0.05), which has the effect of reducing metabolite accumulation and protecting the liver from lipid oxidative damage.

[0034] 5. Regarding hormone levels, please refer to... Figure 5 As shown, compared with the blank group, the serum testosterone and luteinizing hormone levels in the model group mice were significantly decreased (P<0.05), indicating that acute exercise may cause insufficient sex hormone synthesis; compared with the model group, the product group significantly increased testosterone levels (P<0.01).

[0035] 6. Regarding the morphology of testicular and epididymal tissues, please refer to... Figure 6 As shown, acute exhaustive exercise can cause some spermatogenic cells to detach to a certain extent, but the product group's intervention effectively alleviated this phenomenon.

[0036] 7. Regarding sperm abnormality rate, please refer to... Figure 7 As shown, compared with the blank group, the sperm abnormality rate of the model group was significantly increased (p<0.01), indicating that acute exhaustion swimming has a significant impact on sperm morphology. In contrast, the sperm abnormality rate of the product group was significantly lower than that of the model group, and the sperm motility was enhanced.

[0037] In summary, the product of this invention can significantly prolong the time spent swimming to exhaustion, reduce the accumulation of metabolic products and oxidative damage to the liver, regulate hormone levels in male mice and reduce sperm deformity rate, thereby comprehensively enhancing immunity and improving male physiological function.

[0038] Although embodiments of the invention have been shown and described, it will be understood by those skilled in the art that, unless otherwise defined, the technical or scientific terms used in this invention should be understood in the ordinary sense by those skilled in the art to which this invention pertains, and the terms "comprising" or "including" or similar terms used in this invention mean that the element or object preceding the word covers the element or object listed after the word and its equivalents.

[0039] Although embodiments of the invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A sea cucumber peptide solid beverage for enhancing immunity, characterized in that, By weight percentage, its raw materials consist of the following components: sea cucumber peptide ≥50%, Polygonatum sibiricum powder ≥10.55%, wolfberry powder ≥5%, mulberry powder ≥5%, Cistanche deserticola powder ≥4%, Eucommia ulmoides male flower powder ≥1%, Chrysanthemum indicum and Panax notoginseng powder ≥1%, ginseng powder ≥1%, maca powder ≥0.5%, with the remainder being auxiliary raw materials; The auxiliary ingredients include: orange juice powder, maltitol, calcium lactate, ginger powder, silicon dioxide, food processing yeast powder, and steviol glycosides.

2. The sea cucumber peptide solid beverage for enhancing immunity according to claim 1, characterized in that, The nutritional composition of the sea cucumber peptide solid beverage meets the following requirements: per 100g of solid beverage, the protein content is 46.4g-47.1g, the calcium content is 748mg, the iron content is 25.9mg, and the zinc content is 1.04mg.

3. The sea cucumber peptide solid beverage for enhancing immunity according to claim 1, characterized in that, The sea cucumber peptide solid beverage also contains a variety of B vitamins, specifically: per 100g of solid beverage, pantothenic acid 7.47mg, vitamin B1 1.56mg, vitamin B2 1.78mg, nicotinamide 12942μg, and folic acid 361μg.

4. The sea cucumber peptide solid beverage for enhancing immunity according to claim 1, characterized in that, The sea cucumber peptide solid beverage also contains dietary fiber and sugar. Per 100g of solid beverage, the dietary fiber content is 8.2g and the sugar content is 12.5g.

5. A production process for an immune-enhancing sea cucumber peptide solid beverage as described in claim 1, characterized in that, Includes the following steps: a) Raw material procurement and CCP1 raw material inspection: Obtain relevant certificates from suppliers. The purchased raw materials are subject to sensory inspection by the quality control department. They must have the inherent color and odor of the raw materials, and be free from mold, pests and other odors. After acceptance, they are put into storage. b) Procurement and handling of inner packaging materials: After the inner packaging materials are procured and inspected and approved, they are issued for use, unpacked and then sent to the disinfection room for CCP3 disinfection. c) Raw material pretreatment: Raw and auxiliary materials are requisitioned according to production needs, unpacked, and screened. d) CCP2 Ingredients and Mixing: Accurately weigh each raw material component according to the formula ratio, and put the weighed materials into the mixer for thorough mixing to obtain a semi-finished product; e) Inner and outer packaging: The mixed semi-finished products are inner-packaged using the inner packaging material processed in step b), and then outer-packaged after the inner packaging is completed; f) CCP4 X-ray machine inspection: The finished product is inspected for foreign objects by an X-ray machine detector. After passing the inspection, the finished product is put into storage.

6. The production process of a sea cucumber peptide solid beverage for enhancing immunity according to claim 5, characterized in that, In step b), the inner packaging material is disinfected with ozone, and the ozone disinfection time is not less than 30 minutes.

7. The production process of a sea cucumber peptide solid beverage for enhancing immunity according to claim 5, characterized in that, In step f), the detection standard for the X-ray detector is: no metal, ceramic, or glass foreign objects are present in the finished product. The parameters of the X-ray detector are set as follows: iron (FE) ≤ 1.0 mm, stainless steel (SUS) ≤ 2.0 mm, ceramic ≤ 3.0 mm, and glass ≤ 3.0 mm.

8. The application of the sea cucumber peptide solid beverage according to claim 1 in the preparation of health foods or medicines with the following functions: enhancing immunity, anti-fatigue, reducing serum lactic acid content, reducing liver malondialdehyde content, increasing serum testosterone levels, and reducing sperm abnormality rate.

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