Infiltration activation type chemical energy electrode matrix film, and preparation method and application thereof

Abstract

The invention discloses an infiltration activation type chemical energy electrode matrix film and a preparation method and application thereof. A metal compound and metal particles are adopted to construct a positive and negative corresponding uniform array electrode structure, a water-soluble fibrous electrolyte hidden at the bottom of an electrode is arranged in a groove of a matrix bed mould layer, and during use, the electrolyte is infiltrated and dissolved by liquid water naturally possessed by a care solution to obtain an electrolyte; therefore, the positive and negative electrodes are ionized to generate a voltage difference from chemical energy to electric energy. The membrane is attached to the surface of skin, conductive circulation formed by the conductive characteristic of the skin in the direction perpendicular to the skin and a micro electric field formed by the conductive characteristic of the skin in the direction parallel to the skin act on the skin at the same time, effective ingredients of a skin care product can enter the skin more easily, and the purposes of rapidly and effectively maintaining the skin and enhancing the skin care effect are achieved.

Description

Technical Field

[0001] This invention relates to the field of skin care patch technology, specifically to an immersion-activated chemical energy electrode matrix patch, its preparation method, and its application. Background Technology

[0002] Iontophoresis is a well-known and widely used technique in the medical field. It uses electric current to promote the absorption of drugs through the skin. By applying a weak current to the skin surface, it helps charged drug ions penetrate the skin barrier more effectively, thereby enhancing the drug's efficacy.

[0003] Currently, commercially available face masks or patches applied to the skin surface for skin or muscle care mainly rely on the skin's natural absorption of nutrients from the care materials or the effective ingredients in the care solution. This method has a very low efficiency in the actual absorption of effective care ingredients by the skin, and often requires a long application time with little noticeable effect.

[0004] In reality, using a regular face mask to hydrate the skin can only increase the moisture content of the stratum corneum by a maximum of 10%, with very little moisture reaching the stratum lucidum and stratum granulosum, let alone the dermis and basal layer. To increase the effectiveness of skincare masks, some functional masks have emerged on the market, such as AI masks and microcurrent masks. These types of masks primarily use iontophoresis, increasing the skin's absorption saturation of nutrients through microcurrents. With the catalysis of microcurrents, the hydration of the stratum corneum can be increased by more than 50%, allowing nutrients to penetrate deeper into the skin for better care results. However, these masks require an external voltage to generate the current. For example, existing microcurrent masks on the market require a power source, and AI masks require dry batteries and numerous connecting wires. These methods all have drawbacks in terms of ease of use. There are also some therapeutic products that use mechanical methods such as friction or vibration to generate electrical energy to obtain microcurrents for health and care purposes. Furthermore, some patented products, while also utilizing the potential difference between different metals to generate current, require the formulation of a special electrolyte material to be sold alongside the product. This naturally limits their ease of use and scope of application. Additionally, these products often suffer from limited electrical energy, which is insufficient to effectively propel drug ions into the deeper layers of the skin. Summary of the Invention

[0005] This invention provides an immersion-activated chemical energy electrode matrix patch to ensure that active ingredients can be quickly penetrated and absorbed during skin care or repair, thereby enhancing the effect.

[0006] In view of this, the solution of the present invention is as follows:

[0007] The first aspect of the present invention is to provide an immersion-activated chemical energy electrode matrix film, comprising a base layer and a functional carrier layer from bottom to top, the functional carrier layer being a water-absorbing material; the upper surface of the functional carrier layer is coated with a dot matrix of positive and negative electrodes, the positive and negative electrodes alternating sequentially; the surface of the base layer is coated with a dot matrix of aqueous electrolyte, corresponding to the positions of the positive and negative electrodes in the functional carrier layer.

[0008] Furthermore, the tire plate layer is a polymer film with a dot matrix groove, and the aqueous electrolyte is coated in the groove;

[0009] And / or, the absorbent material is selected from one of absorbent polymer membranes, absorbent paper, or nonwoven fabrics.

[0010] Furthermore, the radial dimension of the groove is larger than the dimensions of the positive electrode and the negative electrode;

[0011] And / or, the thickness of the tire plate layer is 20 μm to 120 μm;

[0012] And / or, the thickness of the functional bearing layer is 20 μm to 120 μm.

[0013] Furthermore, the distance between any adjacent positive and negative electrodes is 2.21-10 mm, the diameter of the positive and negative electrodes is 1 mm to 4 mm, and the thickness is 10 μm to 150 μm.

[0014] A second aspect of the present invention is to provide a method for preparing the immersion-activated chemical energy electrode matrix film as described in the first aspect, comprising the steps of:

[0015] S1. A groove array is hot-pressed onto the surface of a polymer membrane, and a water-soluble fibrous electrolyte is printed on it. After drying, a substrate layer coated with a dot matrix water-based electrolyte is obtained.

[0016] S2. A functional load-bearing layer is adhered to the aqueous electrolyte surface of the above-mentioned tire plate layer;

[0017] S3. After coating and drying two conductive ion pastes on the other side of the functional carrier layer, a dot matrix positive electrode and a negative electrode are obtained.

[0018] Further, in step S3, the preparation process of the dot matrix positive electrode and negative electrode is as follows: a first conductive ion paste is dot matrix printed on the surface of the functional carrier layer and dried, and then a second conductive ion paste is dot matrix printed and dried.

[0019] Furthermore, the conductive ion paste used for the positive electrode includes positive electrode conductive particles, a first conductive filler, a first fat-soluble polymer, and a first solvent, and the conductive ion paste used for the negative electrode includes negative electrode conductive particles, a second conductive filler, a second fat-soluble polymer, and a second solvent.

[0020] Preferably, the positive electrode conductive particles are manganese dioxide; And / or, the negative electrode conductive particles are selected from one of Zn, Mg, and Li; And / or, the first conductive filler and the second conductive filler are each independently selected from at least one of carbon black, graphite, carbon nanotubes, and graphene; And / or, the first fat-soluble polymer and the second fat-soluble polymer are each independently selected from at least one of nitro resin, specialty resin, polyurethane, and organic cationic polymer;

[0021] And / or, the first and second solvents are at least one of butyl acetate and propyl acetate.

[0022] Furthermore, the emulsion containing the water-soluble electrolyte is prepared by mixing sodium carboxymethyl cellulose, the water-soluble electrolyte, and water.

[0023] A third aspect of the present invention is to provide the use of the immersion-activated chemical energy electrode matrix patch described in the first aspect, or the immersion-activated chemical energy electrode matrix patch obtained by the preparation method described in the second aspect, in the preparation of skin repair, skin care, or tissue therapy products.

[0024] Furthermore, the application involves applying a nursing nutrient solution or drug solution to the functional carrier layer of the immersion-activated chemical energy electrode matrix film, and then attaching the functional carrier layer to the skin surface.

[0025] Compared with the prior art, the present invention has the following beneficial effects: The immersion-activated chemical energy electrode matrix film provided by this invention constructs a uniform array electrode structure with corresponding positive and negative electrodes. It utilizes the grooves reserved at the bottom of the array electrodes and the plaster layer to arrange the fibrous electrolyte hidden in the grooves. Then, through immersion and dissolution, an electrolyte is obtained, which ionizes the two particle electrodes from the bottom, generating a voltage difference that converts electrochemical energy into electrical energy. When attached to the skin surface, it can utilize the conductivity of the skin to form a conductive loop, generating a conductive current in the vertical direction of the skin and a micro electric field in the parallel direction of the skin, which work simultaneously to make it easier for the care ingredients to enter the skin and form effective and rapid absorption, so as to achieve the purpose of rapid maintenance or enhanced care. The immersion-activated chemical energy electrode matrix film of this invention has 5 electrodes per square centimeter through an equally spaced matrix structure of electrode stagnation points, which can generate 12 current channels. Each unit area receives a uniform current distribution, so that every part of the skin covered by the care film receives the same degree of care and moisturization. This overcomes the problem of uneven use effect caused by the current flowing in only one or a few directions in the prior art. The immersion-activated chemical energy electrode matrix patch of this invention does not rely on an external power source, requires no battery or conductive wires, and does not require a separate electrolyte or the addition of special electrolytes to the skin care solution. Furthermore, before being immersed and activated, the patch itself is non-electrical, with a near-zero voltage difference between the positive and negative electrodes. During use, the liquid components of the nutrient solution or skin care solution dissolve the electrolyte hidden in the grooves at the bottom of each electrode, forming a fibrous electrolyte that reacts with the electrodes at their roots through an oxidation-reduction reaction. This achieves the conversion of chemical energy into electrical energy while the functional carrier layer isolates the electrode from the nutrient solution, preventing the risk of adverse effects from mixing and ensuring the absolute hygiene and safety of the nutrient care solution. This makes it more convenient, faster, and more versatile. Attached Figure Description

[0026] Figure 1 This is a schematic diagram of the immersion-activated chemical energy electrode matrix film according to the present invention.

[0027] Figure 2 This is a schematic diagram of the substrate for the immersion-activated chemical energy electrode matrix film of the present invention.

[0028] Figure 3 This is a schematic diagram of the directional movement of electrons in the positive and negative electrodes of the immersion-activated chemical energy electrode matrix film according to the present invention.

[0029] Figure 4 This is a schematic diagram illustrating the process of using the immersion-activated chemical energy electrode matrix film described in this invention and the effect of generating an internal circuit microcurrent on the skin.

[0030] Figure 5 This is an example of an embodiment of the present invention, showing a wetted activated chemical energy electrode matrix mask prepared and cut. Detailed Implementation

[0031] The technical solution of the present invention will now be clearly and completely described in conjunction with preferred embodiments. Obviously, the described embodiments are only a part of the embodiments of the present invention, and not all of them. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0032] This invention provides an immersion-activated chemical energy electrode matrix film and its preparation method, such as... Figure 1-2 As shown, the film includes a base layer 1 and a functional support layer 2 from bottom to top; the functional support layer 2 is a water-absorbing material; the upper surface of the functional support layer 2 is coated with a dot matrix of positive electrodes 21 and negative electrodes 22, and the positive electrodes 21 and negative electrodes 22 alternate in sequence; the base layer 1 is provided with grooves 11 that correspond one-to-one with the positive and negative electrodes on the functional support layer 2, and the grooves 11 are filled with water-soluble fibrous electrolytes 12.

[0033] Its preparation method includes the following steps:

[0034] S1. Provide a tire plate layer 1; create a groove 11 on the surface of the tire plate layer 1, print a water-soluble fibrous electrolyte in the groove 11, dry and solidify it, and retain the water-soluble fibrous electrolyte 12.

[0035] S2. Adhere a functional bearing layer to the grooved surface of the above-mentioned tire plate layer 1;

[0036] S3. After coating and drying two kinds of conductive particle pastes on the upper surface of the functional carrier layer 2, a dot matrix positive electrode 21 and a negative electrode 22 are obtained.

[0037] In the above embodiments, the immersion-activated chemical energy electrode matrix patch constructs a uniform array electrode structure with corresponding positive and negative electrodes, and utilizes the interlayer spacing of its array structure to arrange electrolytes hidden at the electrode roots. When using care solutions or drug solutions, the naturally occurring liquid water in these liquids is used to immerse and dissolve the electrolytes hidden at the electrode roots, obtaining an electrolyte solution that ionizes the two particles, generating an electrochemical voltage difference. When attached to the skin surface, the conductive properties of the skin are utilized to form a U-shaped conductive loop that penetrates deep into the skin. The conductive current along the vertical direction of the skin and the micro-electric field along the parallel direction of the skin act simultaneously, carrying and propelling drug ions into the skin, achieving rapid and effective absorption of drug components by the skin, and achieving the purpose of enhanced skin care.

[0038] In the above embodiments, by adjusting the spacing between the positive electrode 21 and the negative electrode 22, or the electrode thickness or electrolyte storage capacity, appropriate parameters are controlled to achieve the necessary current intensity for maintenance and treatment. For example, the current generally needs to be above 30uA during treatment, and may even reach 300uA. Specifically, the current intensity for facial care should not be lower than 30uA, and for the care or treatment of other parts of the body, the microcurrent intensity should be at least 50uA. Long-term maintenance of the skin with a 100uA current can promote the growth of skin collagen (from the latest research by American scientists).

[0039] In a preferred embodiment, the distance between any adjacent positive electrode 21 and negative electrode 22 is 2.21-10 mm, the diameter of both positive electrode 21 and negative electrode 22 is 1 mm to 4 mm, and the thickness is 10 μm to 150 μm. The diameter of the groove 11 is larger than the diameter of the positive electrode 21 and negative electrode 22, preferably 1.5 times the diameter of the positive electrode 21 and negative electrode 22, so that after the water-soluble fibrous electrolyte 12 filled in the groove 11 is added with a nursing solution or drug solution, both positive electrode 21 and negative electrode 22 can be immersed in the groove 11 and contact the water-soluble fibrous electrolyte.

[0040] In a preferred embodiment, the material used for the functional carrier layer 2 is selected from one of a water-absorbing polymer membrane, absorbent paper, or non-woven fabric. When using a care solution or drug solution through the functional carrier layer 2, liquid water can directly penetrate into the groove 11, effectively dissolving the aqueous electrolyte 12 in the groove 11 to activate the electrode redox reaction, generating electrical energy, and allowing the care solution or effective drug ion components to directly penetrate into the skin under the impetus of current and electric field.

[0041] In a preferred embodiment, the thickness of the plaster layer 1 is 20 μm to 120 μm; and / or, the thickness of the functional support layer 2 is 20 μm to 120 μm. The plaster layer 1 and the functional support layer 2 require both sufficient load-bearing capacity and flexibility to ensure the film adheres to the skin, allowing the matrix-type positive and negative electrodes to function effectively even in special areas.

[0042] In a preferred embodiment, such as Figure 3 As shown, the distance between any adjacent positive and negative electrodes is equal, forming a matrix electrode stationary point with one positive electrode corresponding to four surrounding negative electrodes and one negative electrode corresponding to four surrounding positive electrodes (excluding edge positions). The diverse current directions and relatively consistent current magnitudes on a single plane facilitate the uniform penetration of the effective ingredients of the treatment or nourishing care solution into the skin surface area, preventing the formation of mottled skin or skin spots.

[0043] In a preferred embodiment, the liner layer 1 is a polymer film with a certain degree of tension and flexibility, preferably a polypropylene film; the functional bearing layer 2 is a structure with permeability, and is selected from water-permeable membranes, such as water-absorbing polymer membranes, absorbent paper, non-woven fabrics, silk materials, biomimetic fiber jellyfish membrane fabrics, Tencel materials, plant cellulose membrane fabrics, etc.

[0044] In step S3 of the preferred embodiment, the preparation process of the dot-matrix positive electrode 21 and negative electrode 22 involves dot-matrix printing of a first conductive ion paste on the surface of the functional carrier layer 2 and drying it, followed by dot-matrix printing of a second conductive ion paste and drying it. The printing process can be performed using a stencil, and the potential difference between the positive and negative electrodes can be controlled by parameters such as the concentration of the conductive ion paste, the coating amount, and the concentration of the aqueous electrolyte. After the water-soluble electrolyte is coated and dried, it forms a fibrous electrolyte that is separated by the functional carrier layer. The fibrous electrolyte, after being wetted by water penetration, forms a hydrogel. It is confined to the root of the electrode and does not easily penetrate back to the upper surface of the functional carrier layer 2.

[0045] In a preferred embodiment, the conductive particle paste used for the positive electrode 21 includes positive conductive particles, a first conductive filler, a first ester-soluble polymer, and a first solvent, and the conductive particle paste used for the negative electrode 22 includes negative conductive particles, a second conductive filler, a second ester-soluble polymer, and a second solvent.

[0046] Specifically, in the above-mentioned positive and negative electrode conductive ion paste:

[0047] The positive electrode particle is manganese dioxide; the negative electrode conductive particle is selected from one of Zn, Mg, and Li; the first conductive filler and the second conductive filler are each independently selected from at least one of carbon black, graphite, carbon nanotubes, and graphene; the first fat-soluble polymer and the second fat-soluble polymer are each independently selected from at least one of nitro resin, special resin, polyurethane, and organic cationic polymer; the first and second solvents are at least one of butyl acetate and propyl acetate.

[0048] In a more preferred embodiment, the conductive particle paste, by weight, comprises 33%–65% positive (negative) polar particles, 0.02%–0.15% monolayer sheet graphene, 5%–15% ester-soluble polymer, and 20%–52.5% mixed solvent. The ester-soluble polymer is preferably a special ink resin, obtained by saponifying and polymerizing unsaturated fatty acids (tung oil or linseed oil) to a suitable viscosity (e.g., 100–1000 centipoise).

[0049] In the above embodiments, the higher the concentration of positive (negative) polar particles added to the conductive particle slurry, the higher the electrode energy density; and the higher the concentration of graphene added, the higher the electrode power density. The advantages of using a specially formulated ink resin to fabricate functional electrodes are: ① It is more compatible with human skin than other resins.

[0050] ② Its combination with polar particles results in a stable yet flexible structure.

[0051] ③ It is not easily hydrolyzed, and the particulate components are stably encapsulated within the electrode body, eliminating physical leakage.

[0052] In a preferred embodiment, the positive (negative) polar particles in the conductive particle slurry undergo pretreatment to enhance reliability and safety: the positive (negative) polar particles are coated into epoxy resin and cured until a protective layer of 50-80 nm is formed on the surface. The purpose is to: ① The nano-coating layer provides open channels for ions and electrons only.

[0053] ②Prevent the physical penetration of particulate impurities, which can cause harmful contact with the skin.

[0054] ③Isolate the color of the particles themselves from seeping out for staining.

[0055] In a preferred embodiment, the emulsion containing water-soluble fibrous electrolyte is prepared from sodium carboxymethyl cellulose, water-soluble electrolyte, and water. More preferably, the components by mass percentage are: 0.5-1% sodium chloride, 3-8% sodium carboxymethyl cellulose, and the balance water; specifically, the sodium carboxymethyl cellulose is first dissolved by heating a portion of the water, and then the required amount of sodium chloride and water is made up with physiological saline.

[0056] It is worth noting that in some embodiments, when using only the water-soluble electrolyte and sodium carboxymethyl cellulose, the loop current consistently failed to exceed 15 μA, making it difficult to meet the required current intensity. However, when these two liquids were mixed together in a certain proportion and then coated onto the positive and negative electrodes, the loop current suddenly increased from 15 μA to 150 μA, an increase of more than 10 times. Analysis suggests that because both substances contain metallic sodium, when the two liquids are mixed and added to the positive and negative electrodes, sodium ions flow towards the positive electrode exponentially, while negative ions and carboxyl ions also flow towards the negative electrode exponentially. This creates a wide channel for electron transfer between the positive and negative electrodes, thus significantly increasing the current intensity.

[0057] Based on the increased current intensity, the film has ample room for adjustment during application. According to the actual power demand, the ideal current intensity can be achieved simply by controlling and adjusting the electrolyte formula, so as to meet a wider range of applications.

[0058] In another embodiment of the present invention, the above-described immersion-activated chemical energy electrode matrix film is used in the preparation of skin repair or care products. A care nutrient solution or drug solution is immersed in the functional carrier layer of the immersion-activated chemical energy electrode matrix film, and one side of the functional carrier layer is adhered to the skin surface. Figure 4 ).

[0059] In a preferred embodiment, the nursing nutrient solution includes, but is not limited to, nutrient water, serum, protein emulsion, and meridian-clearing liquid. After the nursing nutrient solution is applied to the surface of the functional carrier layer, the aqueous components quickly penetrate into the electrode roots. The electrolyte is first dissolved to form an electrolyte with ionization properties. The electrolyte causes oxidation-reduction reactions at the functional array stagnation points to generate electrical energy, forming multiple corresponding charged electrodes. When attached to the skin surface, current channels are formed between adjacent electrodes through the conductivity of the skin, generating current. Due to the characteristic that the resistance between the skin surface gaps is much greater than the resistance of the skin thickness, and the resistance of the subcutaneous tissue is much lower than the resistance of the epidermis, following the principle that current does not travel long distances, most of the current will penetrate the skin from the positive electrode, then through the intradermal tissue to the skin at the negative electrode, and then penetrate the skin back to the negative electrode. The flow of current will induce an electric field. Figure 4 The electric current creates an iontophoresis effect on the skin surface, which helps promote the penetration of effective ionic components in skincare products into the deeper layers of the skin, thereby improving the efficiency and efficacy of skincare treatments. It can be cut to fit specific tissue shapes, such as... Figure 5 The face mask shown.

[0060] In a preferred embodiment, the above-mentioned film can meet the following current control intensity requirements: 1) Adjustable current for beauty and skincare devices: 0~1.2 mA / cm² 2 ; 2) For actual facial care, the following concentration is typically used: 0.03–0.05 mA / cm² 2 ; 3) Care for other areas: 0.05~0.1 mA / cm 2 ; 4) Special care areas: 0.1–0.8 mA / cm 2 ; 5) Sensitive areas around the eyes: 0.1–0.3 mA / cm 2 .

[0061] In this invention, the selection principle for the electrode spacing is as follows: 1) The selection of the maximum spacing needs to meet the requirement of effective current coverage within a very small unit area. The maximum electrode spacing of this invention is determined to be 10mm, that is, there are 12 directions per square centimeter, and the maximum intensity is 0.23mA×12 / cm. 2 The current effectively covers the area; 2) The internal circuit formed by each electrode (less than 1cm) 2 The current needs to be greater than 0.05mA to ensure the effectiveness of iontophoresis.

[0062] Internal circuit electrical performance: a. The surface resistivity of skin is generally 3 kΩ; b. The electrical resistance of the human body is generally 0.5 kΩ; c. Internal loop impedance = 3kΩ + 0.5kΩ + 3kΩ = 6.5kΩ; d. The voltage V when the internal circuit reaches a current of 0.05mA is V = 0.00005 × 6500 = 0.325V.

[0063] In other words, the basic conditions for iontophoresis are met when the voltage is only higher than 0.325 V. In the scheme of this invention, 1 cm... 2 It can provide a power supply voltage of 1.2 volts or higher, sufficient for iontophoresis technology, with a maximum therapeutic current greater than 0.23 mA × 12 / cm. 2 Sufficient for physical therapy needs.

[0064] 3) Principles for selecting minimum spacing

[0065] The thickness of the skin surface layer is typically 0.2mm (varies from person to person), with an impedance of 3KΩ. The internal impedance of the human body is 0.5kΩ. The inner circuit impedance equals 3KΩ + 0.5KΩ + 3KΩ = 6.5KΩ. When the patch is applied to the epidermis, the skin resistance between the two electrodes directly affects whether the inner circuit can obtain sufficient electrical energy. To ensure sufficient current in the inner circuit, the spacing between the two electrodes needs to be appropriate. If the electrode spacing is too large, it will affect the current coverage of the inner surface of the skin; if the density is too small, the skin surface resistance will compete with the current in the inner circuit. Therefore, choosing an appropriate electrode spacing is particularly important. In this example, a scheme is chosen where the skin resistance between the electrodes is 3 times that of the inner circuit. Considering that the resistance will decrease by 70% when the skin is wet, the reasonable electrode spacing is designed as follows:

[0066] The minimum electrode spacing ≥ inner circuit impedance (6.5kΩ) × 3 × 1.7 × 170% ÷ skin resistance 3000 ÷ 0.2mm ≥ 6500 × 3 × 1.7 ÷ 3000 ÷ 0.2 ≥ 33150 ÷ ​​15000 ≥ 2.21mm. That is, an electrode spacing greater than or equal to 2.21mm meets the practical requirements. In summary, Figure 4 The range of LR values ​​is: 2.21mm≤LR≤10mm.

[0067] Preparation Example 1: Pretreatment of Positively and Negatively Conductive Particles 1. Add 200ml of butyl acetate to a 1000ml glass beaker, then add 1.2g of epoxy resin. Next, add 40g of manganese dioxide (or zinc powder, etc.) to the beaker in 10 portions (1 minute apart). Place the beaker in a temperature-controlled oven, set the temperature to 76℃, and stir slowly with a stirring rod for 24 hours.

[0068] 2. After filtration and drying, 40g of positive (or negative) conductive particles with an epoxy resin film with a thickness of 50nm to 80nm are obtained.

[0069] 3. Testing and effectiveness of the coating film A. Preparation of test samples ① Take 5 grams of two-component epoxy resin and add red dye, then stir thoroughly.

[0070] ② Add the positive or negative polar particles that have been coated with epoxy film to the above-mentioned dyed epoxy resin, stir evenly, and then place in an oven at 150℃ for curing.

[0071] ③ The cured block of red resin is placed on a flat grinder and ground until the granular material of the coating is exposed to obtain the test sample.

[0072] B. Observation and detection under a mirror microscope: ① The thickness of the epoxy resin coating layer of the particles was measured to be between 50 nm and 80 nm.

[0073] ② Observe the broken part of the coating layer and whether the color of the particles and the outer side of the coating layer is consistent with the color of the dyed epoxy resin. If the color of the coating layer is the natural color of the epoxy resin, it is qualified. If it is not the natural color but red, it means that the coating layer has bleed color. If such coated particles are used to produce immersion chemical energy matrix films, the color of the particles will penetrate into the skin to be applied.

[0074] Preparation Example 2: Preparation of Special Ink Resin

[0075] 1. Grease rinsing

[0076] Add 100 kg of the selected oil (cattail oil or linseed oil) to the reactor and heat it with steam while stirring at a speed of 30 r / min.

[0077] 2. Acid-base neutralization

[0078] When the temperature is raised to 90℃, the acid value is measured and the acid content is calculated. Then, sodium hydroxide of the acid value equivalent is added, stirred evenly, and allowed to cool naturally and stand for 24 hours to separate into layers before draining the soap pods from the bottom.

[0079] 3. Second rinse

[0080] Pour 95°C hot water into the reactor and rinse it repeatedly 5 times, then let it stand for 24 hours.

[0081] 4. Polymerization reaction

[0082] After removing the soapberry, heat the reactor to 280°C and maintain the temperature for about 20 hours. Starting from the 20th hour, check the reaction viscosity of the material every 5 minutes. When the viscosity reaches 700 centipoise, begin to cool down naturally. The special ink resin is now ready.

[0083] Preparation Example 3: Preparation of Positive (Negative) Electrode Particle Slurry

[0084] 1. Add 33-65% positive polar particles, 0.02-0.15% monolayer sheet graphene, 5-15% special ink resin, and 20-52.5% mixed solvent (add 10-30% first, and then add the rest after mixing) to the mixing tank by mass percentage, and stir in a low-speed mixer for 10 minutes. The mixed solvent by volume percentage is: 50% butyl acetate and 50% ethyl acetate.

[0085] 2. Add the above-stirred material to the sand mill produced by General Ink and disperse it thoroughly.

[0086] 3. Add the remaining mixed solvent to the slurry and stir in a low-speed mixer for 15 minutes to obtain a special ink that can be used for printing (adding positive polar particles yields positive polar ink; adding negative polar particles yields negative polar ink).

[0087] Preparation Example 4: Preparation of a water-soluble electrolyte fibrous solution

[0088] 1. Add 50g of distilled or purified water to a beaker, heat the water and maintain the temperature at 45℃.

[0089] 2. Slowly add 5g of sodium carboxymethyl cellulose to the beaker while stirring to dissolve it completely.

[0090] 3. Add 50g of 0.9% physiological saline to a beaker while stirring to form an emulsion solution. The preparation is now complete.

[0091] Preparation Example 5: Preparation of Immersion-Activated Chemical Energy Electrode Matrix Film

[0092] 1. Press respectively Figure 1 Steel mesh A and steel mesh B are fabricated at the positions of the positive electrode 21 and negative electrode 22, respectively. Each mesh has an array of holes, each with a diameter of 1 mm, and the distance between adjacent holes ranges from 2.21 to 10 mm. Both steel meshes are 50 μm thick. Steel mesh C is used to coat the water-soluble electrolyte layer 12; it is 30 μm thick and has a diameter of 1.5 mm. The thicknesses of steel meshes A, B, and C constitute the printing thickness.

[0093] 2. Take a non-woven fabric (20μm to 120μm thick) as the functional carrier layer 2. Using a special ink, print the positive electrode points on the surface of the functional carrier layer using a regular stencil printing method with a stencil pattern A. After hot air curing, print the negative electrode points using the same printing method with stencil B. After hot air curing, a matrix of electrodes is formed with evenly spaced arrays, where one positive electrode corresponds to four negative electrodes and one negative electrode corresponds to four positive electrodes. Then, using a stencil, print or spray the prepared water-soluble electrolyte emulsion into the grooves of the substrate under mold control. After hot air evaporation and curing, a fibrous electrolyte is formed. Then, under the control of a positioning mold, attach the functional carrier layer to the substrate layer, so that the positive and negative electrodes on the functional carrier layer exactly overlap with the grooves on the substrate layer. The above process yields a preform of the immersion chemical energy matrix film.

[0094] 3. The preform is cut into the required shape to obtain the immersion-activated chemical energy electrode matrix film.

[0095] Examples 1-3, Comparative Examples 1-2

[0096] Materials for each step were prepared according to the preparation examples 1-5 above, and finally, an immersion chemical energy matrix film was prepared. The specific materials and parameter ranges are shown in Table 1. For parameters not covered, the preparation examples above were followed.

[0097] Table 1:

[0098] Note: LR / mm represents the electrode spacing printed using different spacing molds. Different spacings were selected for the various embodiments in the table.

[0099] Five products with different formulations were prepared according to the above examples and comparative examples, and their electrical performance was tested respectively.

[0100] Test case

[0101] 1. Resistance and voltage / current detection (without liquid water wetting)

[0102] ① Resistance:

[0103] Set the multimeter to the R (MΩ) range. Connect the red probe to any positive or negative electrode point, and the black probe to any other electrode on the matrix. The resistance value should be infinite (see Table 2, Resistance Ω). Then, reverse the red and black probes and measure again. The resistance value should also be infinite. Otherwise, if the resistance value decreases at any point, the product is defective.

[0104] ② Voltage:

[0105] Set the multimeter to the V- range. Connect the red probe to any set of positive electrodes in sequence, and the black probe to any set of negative electrodes in sequence. Measure the DC voltage between any set of positive electrodes and the corresponding negative electrodes. The test results are shown in Table 2 (voltage in mV). (If it is greater than 50mV, it indicates that the screen protector is close to being damp).

[0106] ③ Current:

[0107] Set the multimeter to the DC current range. Connect the red probe to the positive electrode in sequence, and the black probe to the negative electrode in sequence. Measure the DC current between any pair of positive electrodes and their corresponding adjacent negative electrodes. The results are shown in Table 2 (current uA). If there is leakage current, the multimeter is faulty.

[0108] The detection results of each embodiment and comparative example using the above detection methods are shown in Table 2.

[0109] Table 2:

[0110] Note: 1) The voltage mV index refers to the voltage difference between each positive electrode or each negative electrode and its adjacent reverse electrode before use, that is, before it has been cleaned by the water-based material. This voltage difference is very small and not completely consistent; it reflects the sum of multiple sets of data and is a data range.

[0111] 2) The indicators given in the embodiments of the present invention are actual measurement data. The data tested before and after use, as well as the measured data after swapping another adjacent electrode, will differ between adjacent electrodes and are not absolutely equal. The table shows the data distribution range of multiple sets of electrode measurements.

[0112] 2. Electrical performance indicators (tested in a clear liquid water state at time points of 0.5 minutes, 1 minute, 4 minutes, 8 minutes, 16 minutes, and 40 minutes):

[0113] Spray distilled water or skin-nourishing toner onto the surface of the functional carrier layer. The electrolyte hidden at the bottom of the electrodes will preferentially dissolve in the water, forming an electrolyte solution that ionizes the positive and negative electrodes. Set the multimeter to the DC voltage range.

[0114] ① Connect the red probe to any positive electrode, and the black probe to each of the four adjacent negative electrodes corresponding to that positive electrode. The voltage should be greater than 1V and less than 1.5V. There is a voltage difference between each positive electrode and its four adjacent negative electrodes.

[0115] ② Connect the black probe to any negative electrode, and the red probe to each of the four adjacent positive electrodes corresponding to that negative electrode. The negative voltage will be greater than 1V and less than 1.5V. There is a voltage difference between each negative electrode and its four adjacent positive electrodes.

[0116] Then set the multimeter to the DC current setting:

[0117] ① Connect the red probe to any positive electrode, and connect the black probe to the four negative electrodes corresponding to that positive electrode. The current is greater than 50uA and increases with time within a finite time.

[0118] ② Connect the black probe to any negative electrode, and connect the red probe to the four positive electrodes corresponding to that negative electrode. The current in each electrode is greater than 50uA and increases with time within a finite time.

[0119] The electrical performance indicators of Examples 1-3 and Comparative Examples 1-2 were tested according to the above method, and the results are shown in Table 3.

[0120] Table 3:

[0121] analyze: 1) Voltage and current show a rapid upward trend before 4 minutes, reach their peak at 8 minutes, and then show a downward trend from 8 minutes to 16 minutes. After 16 minutes, they drop rapidly and tend to 0.

[0122] 2) As can be seen from Examples 1-3, adjusting the concentration of positive and negative electrode particles has a slight impact on the output of electrical energy.

[0123] 3) Comparative Examples 1 and 2 show that the electrolyte of the element has limited effect on improving electrical performance.

[0124] 4) Comparing the comparative examples with the implementation examples, it can be seen that the composite electrolyte has a significant impact on electrical performance.

[0125] Furthermore, the sodium carboxymethyl cellulose solution, after solidification and subsequent wetting, forms a hydrogel state, which prevents it from spreading over a large area or to the other side of the functional layer, thus ensuring the purity of the nutrient care solution on the other side of the functional layer. In addition, different printing thicknesses of the electrodes have a significant impact on the release time of electrical energy, which is of great practical significance for the various applications of this invention.

[0126] Application example: patch application experience

[0127] A 5cm x 8cm piece was randomly cut from the pre-made membrane prepared in Example 1, and each piece was soaked in the nutrient solution of the facial mask. These pieces were then applied to the skin of one arm of each of the five subjects. A 5cm x 8cm piece was then cut from a regular facial mask, moistened with the same nutrient solution, and applied to the skin of the other arm of each of the five subjects. After 8 minutes, the masks were removed, and the application effect was observed visually. The results are as follows:

[0128] ① None of the 5 subjects experienced any discomfort or other adverse sensations during the application period.

[0129] ② Microcurrent film application effect: a. No staining phenomenon; b. The skin after application is noticeably more moisturized, radiant, and elastic compared to the surrounding skin; c. Repeated testing of the electrical performance of each electrode showed no significant changes in the indicators; d. After letting the film stand for 40 minutes, the electrical performance was tested again. The voltage dropped slightly and the current dropped below 5uA.

[0130] ③ Regular screen protector effect:

[0131] a. No staining phenomenon

[0132] b. There are slight marks compared to the surrounding skin where the film was not applied.

[0133] The above experiments demonstrate that:

[0134] 1) Microcurrent film application has no side effects.

[0135] 2) Microcurrent screen protector application is significantly more effective than regular screen protector application.

[0136] 3) The power density of the positive and negative electrodes of the microcurrent patch is sufficient during the nursing period, and the power gradually disappears after the nursing period.

[0137] Although embodiments of the invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. An immersion-activated chemical energy electrode matrix film, characterized in that, It includes a tire plate layer (1) from bottom to top and a functional support layer (2). The functional support layer (2) is made of water-absorbing material. The upper surface of the functional support layer (2) is coated with a dot matrix positive electrode (21) and a negative electrode (22), which alternate in sequence. The surface of the tire plate layer (1) is coated with a dot matrix aqueous electrolyte (12), which corresponds to the position of the positive electrode (21) and the negative electrode (22) in the functional support layer (2).

2. The immersion-activated chemical energy electrode matrix film according to claim 1, characterized in that, The tire plate layer (1) is a polymer film with dot matrix grooves (11), and the aqueous electrolyte (12) is coated in the grooves (11); And / or, the absorbent material is selected from one of absorbent polymer membranes, absorbent paper, or nonwoven fabrics.

3. The immersion-activated chemical energy electrode matrix film according to claim 2, characterized in that, The radial dimension of the groove (11) is larger than the dimensions of the positive electrode (21) and the negative electrode (22); And / or, the thickness of the tire plate layer (1) is 20 μm to 120 μm; And / or, the thickness of the functional carrier layer (2) is 20 μm to 120 μm.

4. The immersion-activated chemical energy electrode matrix film according to claim 1, characterized in that, The distance between any adjacent positive electrode (21) and negative electrode (22) is 2.21-10 mm. The diameter of the positive electrode (21) and negative electrode (22) is 1 mm to 4 mm, and the thickness is 10 μm to 150 μm.

5. The method for preparing the immersion-activated chemical energy electrode matrix film according to any one of claims 1-4, comprising the following steps: S1. A groove (11) is hot-pressed into an array on the surface of a polymer membrane, and a water-soluble fibrous electrolyte is printed on it. After drying, a plating layer (1) coated with a dot matrix aqueous electrolyte (12) is obtained. S2. Adhere the functional carrier layer (2) to the aqueous electrolyte surface of the above-mentioned tire plate layer. S3. After coating and drying two conductive ion pastes on the other side of the functional carrier layer (2), a dot matrix positive electrode (21) and a negative electrode (22) are obtained.

6. The preparation method according to claim 5, characterized in that, In step S3, the preparation process of the dot matrix positive electrode (21) and negative electrode (22) is as follows: a first conductive ion paste is dot matrix printed on the surface of the functional carrier layer and dried, and then a second conductive ion paste is dot matrix printed and dried.

7. The preparation method according to claim 5, characterized in that, The conductive ion paste used in the positive electrode (21) includes positive electrode conductive particles, a first conductive filler, a first fat-soluble polymer and a first solvent, and the conductive ion paste used in the negative electrode (22) includes negative electrode conductive particles, a second conductive filler, a second fat-soluble polymer and a second solvent.

8. The preparation method according to claim 7, characterized in that, The positive electrode conductive particles are manganese dioxide; And / or, the negative electrode conductive particles are selected from one of Zn, Mg, and Li; And / or, the first conductive filler and the second conductive filler are each independently selected from at least one of carbon black, graphite, carbon nanotubes, and graphene; And / or, the first fat-soluble polymer and the second fat-soluble polymer are each independently selected from at least one of nitro resin, specialty resin, polyurethane, and organic cationic polymer; And / or, the first and second solvents are at least one of butyl acetate and propyl acetate.

9. The preparation method according to claim 5, characterized in that, The emulsion containing the water-soluble electrolyte is prepared by mixing sodium carboxymethyl cellulose, the water-soluble electrolyte, and water.

10. The application of the immersion-activated chemical energy electrode matrix film according to any one of claims 1-4, or the immersion-activated chemical energy electrode matrix film obtained by the preparation method according to any one of claims 5-9, in the preparation of skin repair, skin care, or tissue therapy products.

Images