Clinical evaluation system and method for growth and development of children

Abstract

The invention discloses a clinical evaluation system and method for growth and development of children, and relates to the technical field of children health monitoring, and the clinical evaluation system comprises a multi-modal data acquisition module, a data processing and analysis module and an intervention and feedback module. According to the clinical evaluation system and method for growth and development of children, basic parameter conditions, traditional Chinese medicine syndrome conditions, serum growth and development conditions and adverse reaction conditions of children are analyzed one by one through the data processing and analysis module, and analysis is performed according to evaluation results to generate a personalized intervention scheme to realize re-evaluation operation; fusion analysis is carried out on accurate measurement of modern medicine and overall differentiation of traditional Chinese medicine, a medicine-psychology-behavior three-dimensional intervention system is formed, and long-term, dynamic and efficient management of growth and development of children is achieved.

Description

Technical Field

[0001] This invention relates to the field of children's health monitoring technology, specifically to a clinical assessment system and method for children's growth and development. Background Technology

[0002] With the development of the social economy, parents' focus on children's height has shifted from "disease treatment" to "health management," prompting a rapid increase in the market demand for interventions in children's growth and development. Growth and development are important characteristics that distinguish children from adults. Currently, the assessment of children's growth and development mainly relies on regular physical examinations and doctors' experience.

[0003] The reference patent title is: A system for detecting and assessing the quality of children's growth and development (Patent Publication No.: CN111407285A, Patent Publication Date: 2020-07-14). It includes a developmental testing bed with a groove on its top surface. A weighing platform is embedded in the groove. A first hydraulic cylinder is fixedly installed on the right wall of the developmental testing bed. The output end of the first hydraulic cylinder passes through the right wall of the developmental testing bed and the groove and is fixedly connected to a first headband. A first infrared sensor is fixedly installed at one end of the bottom surface of the first headband. A base is fixedly installed on the lower left wall of the developmental testing bed, and a weight scale is slidably embedded in the bottom surface of the base. This system can simultaneously detect the growth and development quality of children of different ages, with high efficiency. Doctors only need to transcribe the data on the display screen. Simultaneously, length / height, weight, and head circumference are measured. The operation is simple and highly efficient, reducing the workload of medical staff.

[0004] Based on the above-mentioned documents, existing assessment procedures rely on doctors' personal clinical experience, lack integrated support from traditional Chinese medicine and psychological intervention, and view growth issues in isolation, leading to the neglect of the synchronous influence of multiple factors on development. As a result, the assessment results are inaccurate, affecting treatment procedures. Therefore, this invention provides a clinical assessment system and method for children's growth and development. Summary of the Invention

[0005] To address the shortcomings of existing technologies, this invention provides a clinical assessment system and method for children's growth and development. It solves the problems of existing assessment procedures relying on doctors' personal clinical experience, lacking integrated auxiliary procedures of traditional Chinese medicine and psychological intervention, and viewing growth issues in isolation, which leads to the neglect of the synchronous influence of multiple factors on development, resulting in inaccurate assessment results and affecting treatment procedures.

[0006] To achieve the above objectives, the present invention provides the following technical solution: a clinical assessment system for children's growth and development, comprising: The multimodal data acquisition module collects various types of raw data related to children's growth and development, and transmits and stores the data; The data processing and analysis module receives raw data from the data acquisition module, classifies and integrates it, and analyzes the child's basic parameters, TCM syndromes, serum growth and development, and adverse reactions one by one. It combines the analysis results to obtain corresponding diagnostic results, and synthesizes the analysis results to obtain clinical assessment values. By comparing the clinical assessment values ​​with the set assessment criteria table, the current growth and development status of the child is determined. The intervention and feedback module generates personalized intervention plans based on children's growth and development, and simultaneously records the implementation of intervention measures and subsequent feedback data to form a closed loop, which is used to evaluate the intervention effect and optimize the plan.

[0007] Preferably, the children whose data are collected by the multimodal data acquisition module must meet the following requirements: the children are between 5 and 16 years old, all family members have given informed consent to the collection of the children's growth and development data and have signed informed consent forms, the children do not have mental illness or cognitive impairment, and they are not using drugs that affect growth.

[0008] Preferably, the operation of receiving and classifying the raw data from the data acquisition module in the data processing and analysis module is as follows: Set up an integrated table with basic parameters, TCM syndromes, serum growth and development, and adverse reactions as the main headings in the horizontal position; Furthermore, the vertical row headings starting from the third row of the first column of the integrated table are filled with the timestamps of different data collections, while the horizontal column headings starting from the second column of the second row of the integrated table are filled with the names of various categories corresponding to basic parameters, TCM syndromes, serum growth and development, and adverse reactions. The column headings are adapted to the length of multiple category names under the main heading to expand the main heading. Then, based on the category name and timestamp, the content matching operation with the collected data is completed, and the result data under the corresponding category of the collected data is filled into the table column where the category name is located and the timestamp is located.

[0009] Preferably, the expansion operation of the main title, adapted to the length of multiple category names under the main title, is as follows: Set the maximum table length for a single category name to 'a', and the number of corresponding category names to 'n'. If the number of single category names does not exceed the maximum table length 'a', then the table length occupied by the single category name in real time is marked as 'b'. Conversely, if the number of single category names exceeds the maximum table length 'a', then the table length is marked as 'a', and the vertical position of the table is expanded. The expansion of the main title is achieved by summing the table length occupied by each category name under the corresponding main title, which is the length of the main title table column. If the summed main title table column length is greater than the initial main title table column length, the initial main title table column will be expanded according to the summed main title table column length, and the content of the main title table column will be centered.

[0010] Preferably, the operation of analyzing the child's basic parameters in the data processing and analysis module is as follows: We extract children’s weight and height data at the initial stage and subsequent cyclical time stages, and at the same time extract standard reference data of children of the same age and gender to generate normal reference intervals. 通过对同一周期时间阶段下单个儿童的同类别的多次数据结果进行提取，并根据数据结果得出平均值，再将相邻周期时间阶段下的同类别数据的变化率得出后与 正常参考区间进行比较并生成基本参数情况评估值标为cx； 比较结果为：体重变化率属于体重正常参考区间，身高变化率属于或高于身高正常参考区间，则设定当前基本参数情况评估值为c1，体重变化率属于体重正常参 考区间，身高变化率小于身高正常参考区间，则设定当前基本参数情况评估值为c2，体重变化率大于体重正常参考区间，身高变化率属于或高于身高正常参考区间，则设定当前基 本参数情况评估值为c3，体重变化率大于体重正常参考区间，身高变化率小于身高正常参考区间，则设定当前基本参数情况评估值为c4，且c1＜c3＜c2＜c4＜25。

[0011] Preferably, the operation of analyzing TCM syndromes in the data processing and analysis module is as follows: By matching the physical condition of children identified by TCM experts with the TCM syndrome knowledge base, and confirming whether there are conditions such as slow growth, yellowing and sparse hair, sallow complexion, thin body, irregular bowel movements and loss of appetite based on the data; At the same time, the TCM syndrome assessment value is obtained based on the severity of each confirmed condition. The smaller the assessment value is when a single confirmed condition is mild, the larger the assessment value is when a single confirmed condition is severe. Then, the assessment values ​​of each confirmed condition are added together to obtain the TCM syndrome assessment value, and the TCM syndrome assessment value is not higher than 25.

[0012] Preferably, the data processing and analysis module includes the operation of analyzing serum growth and development status: The concentration of insulin-like growth factor-1 in serum was extracted, and 5 mL of fasting venous blood was drawn in the morning for data collection. The hemoglobin level was detected by routine blood tests, and the concentration of insulin-like growth factor-1 in serum was determined by chemiluminescence technology. At the same time, growth hormone indicators were extracted from historical data, and the measured insulin-like growth factor-1 concentration was compared with the corresponding growth hormone indicators to obtain the serum growth and development assessment value. When the concentration of insulin-like growth factor-1 is lower than the growth hormone level, the serum growth and development status is deficient in growth hormone, and the serum growth and development status assessment value is 25. Conversely, when the concentration of insulin-like growth factor-1 is normal, the serum growth and development status assessment value is 0.

[0013] Preferably, the data processing and analysis module performs the following operations to analyze adverse reactions: Extract children's adverse reaction history and automatically compare the components of adverse reactions with the components used in the intervention program; If there are known allergens or contraindicated ingredients, a risk warning will be generated and the doctor will be informed to adjust the strategy. If there are no allergens, the current adverse reaction assessment value will be determined based on the number of adverse reactions that occur within the same period. The more times the adverse reactions occur, the higher the corresponding adverse reaction assessment value will be, and the adverse reaction assessment value will not exceed 25.

[0014] Preferably, the operation of comparing the clinical assessment value with the established assessment criteria table is as follows: The clinical assessment value is obtained by summing the basic parameter assessment values, TCM syndrome assessment values, serum growth and development assessment values, and adverse reaction assessment values ​​obtained from the analysis. The clinical assessment value is then compared with the assessment criteria table to determine the child's growth and development status. Based on the determination of the child's growth and development, a personalized intervention plan is generated. The intervention plan combines a liver-soothing, intelligence-enhancing, vision-improving, and height-increasing plaster with placebo therapy and massage therapy at corresponding acupoints. After the intervention, the data is extracted and re-evaluated.

[0015] This invention also discloses a clinical assessment method for children's growth and development, specifically including the following steps: S1. Collect various data related to children's growth and development; S2. To perform data analysis and operation, combine the precise measurement of modern medicine with the holistic diagnosis of traditional Chinese medicine to assess the growth and development of children, and generate personalized intervention plans based on the assessment of children's growth and development. S3. After the child receives intervention treatment based on the personalized intervention plan, a reassessment is conducted to determine whether the child's growth and development have improved.

[0016] This invention provides a clinical assessment system and method for children's growth and development. Compared with existing technologies, it has the following advantages: 1. This clinical assessment system and method for children's growth and development analyzes children's basic parameters, TCM syndromes, serum growth and development, and adverse reactions through a data processing and analysis module. Based on the assessment results, it generates personalized intervention plans for reassessment. It integrates the precise measurement of modern medicine with the holistic diagnosis of TCM to form a three-dimensional intervention system of "drug-psychology-behavior", which enables long-term, dynamic, and efficient management of children's growth and development.

[0017] 2. This clinical assessment system and method for children's growth and development uses an integrated table with basic parameters, TCM syndromes, serum growth and development data, and adverse reactions as the main headings. The table adapts to the length of multiple categories under each heading, allowing for expansion of the heading and resolving data fragmentation issues. It also ensures data accuracy, enabling doctors to readily grasp children's growth and development information throughout their entire lifecycle. This significantly reduces data search and integration time, laying a solid foundation for comprehensive analysis.

[0018] 3. This clinical assessment system and method for children's growth and development analyzes children's basic parameters, TCM syndromes, serum growth and development, and adverse reactions one by one, and combines the analysis results to obtain corresponding diagnostic results. It sets clear quantitative assessment value calculation rules, which makes the assessment results standardized, measurable, and comparable, greatly reducing the judgment bias caused by differences in doctors' experience. In addition, the combination of multi-source factor analysis effectively fills the gap in the cross-disciplinary research of "syndrome differentiation and treatment - modern pathology" in the field of growth and development delay. Attached Figure Description

[0019] Figure 1 This is a schematic diagram of the clinical assessment system of the present invention; Figure 2 This is a flowchart illustrating the operation of the clinical assessment method of the present invention. Figure 3 This is a flowchart of the operation of the control experiment of the present invention. Detailed Implementation

[0020] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0021] Please see Figures 1-2 This invention provides two technical solutions: Example 1: A clinical assessment system for children's growth and development, comprising: The multimodal data acquisition module collects various types of raw data related to children's growth and development, and transmits and stores the data; The data processing and analysis module receives raw data from the data acquisition module, classifies and integrates it, and analyzes the child's basic parameters, TCM syndromes, serum growth and development, and adverse reactions one by one. It combines the analysis results to obtain corresponding diagnostic results, and synthesizes the analysis results to obtain clinical assessment values. By comparing the clinical assessment values ​​with the set assessment criteria table, the current growth and development status of the child is determined. The intervention and feedback module generates personalized intervention plans based on children's growth and development, and simultaneously records the implementation of intervention measures and subsequent feedback data to form a closed loop, which is used to evaluate the intervention effect and optimize the plan.

[0022] The data processing and analysis module analyzes children's basic parameters, TCM syndromes, serum growth and development, and adverse reactions one by one. Based on the evaluation results, it generates personalized intervention plans for re-evaluation. It integrates the precise measurement of modern medicine with the holistic diagnosis of TCM to form a three-dimensional intervention system of "drug-psychology-behavior", which realizes long-term, dynamic and efficient management of children's growth and development.

[0023] In this embodiment of the invention, the children whose data are collected by the multimodal data acquisition module must meet the following requirements: the children are between 5 and 16 years old, all family members have given informed consent to the collection of the children's growth and development data and have signed informed consent forms, the children do not have mental illness or cognitive impairment, and they do not use drugs that affect growth.

[0024] In this embodiment of the invention, the operation of receiving and classifying raw data from the data acquisition module in the data processing and analysis module is as follows: Set up an integrated table with basic parameters, TCM syndromes, serum growth and development, and adverse reactions as the main headings in the horizontal position; Furthermore, the vertical row headings starting from the third row of the first column of the integrated table are filled with the timestamps of different data collections, while the horizontal column headings starting from the second column of the second row of the integrated table are filled with the names of various categories corresponding to basic parameters, TCM syndromes, serum growth and development, and adverse reactions. The column headings are adapted to the length of multiple category names under the main heading to expand the main heading. Then, based on the category name and timestamp, the content matching operation with the collected data is completed, and the result data under the corresponding category of the collected data is filled into the table column where the category name is located and the timestamp is located.

[0025] In this embodiment of the invention, the expansion operation of the main title is adapted to the length occupied by multiple category names under the main title as follows: Set the maximum table length for a single category name to 'a', and the number of corresponding category names to 'n'. If the number of single category names does not exceed the maximum table length 'a', then the table length occupied by the single category name in real time is marked as 'b'. Conversely, if the number of single category names exceeds the maximum table length 'a', then the table length is marked as 'a', and the vertical position of the table is expanded. The expansion of the main title is achieved by summing the table length occupied by each category name under the corresponding main title, which is the length of the main title table column. If the summed main title table column length is greater than the initial main title table column length, the initial main title table column will be expanded according to the summed main title table column length, and the content of the main title table column will be centered.

[0026] By setting up an integrated table with basic parameters, TCM syndromes, serum growth and development, and adverse reactions as the main headings in the horizontal position, the table adapts to the length of multiple category names under the main heading, allowing for expansion of the main heading. This solves the problem of data fragmentation and ensures data accuracy, enabling doctors to grasp the child's growth and development information throughout the entire cycle at a glance. It greatly reduces the time spent on data searching and integration, laying a solid foundation for comprehensive analysis.

[0027] In this embodiment of the invention, the operation of analyzing the basic parameters of children in the data processing and analysis module is as follows: We extract children’s weight and height data at the initial stage and subsequent cyclical time stages, and at the same time extract standard reference data of children of the same age and gender to generate normal reference intervals. 通过对同一周期时间阶段下单个儿童的同类别的多次数据结果进行提取，并根据数据结果得出平均值，再将相邻周期时间阶段下的同类别数据的变化率得出后与 正常参考区间进行比较并生成基本参数情况评估值标为cx； 比较结果为：体重变化率属于体重正常参考区间，身高变化率属于或高于身高正常参考区间，则设定当前基本参数情况评估值为c1，体重变化率属于体重正常参 考区间，身高变化率小于身高正常参考区间，则设定当前基本参数情况评估值为c2，体重变化率大于体重正常参考区间，身高变化率属于或高于身高正常参考区间，则设定当前基 本参数情况评估值为c3，体重变化率大于体重正常参考区间，身高变化率小于身高正常参考区间，则设定当前基本参数情况评估值为c4，且c1＜c3＜c2＜c4＜25。

[0028] In this embodiment of the invention, the operation of analyzing TCM syndromes in the data processing and analysis module is as follows: By matching the physical condition of children identified by TCM experts with the TCM syndrome knowledge base, and confirming whether there are conditions such as slow growth, yellowing and sparse hair, sallow complexion, thin body, irregular bowel movements and loss of appetite based on the data; At the same time, the TCM syndrome assessment value is obtained based on the severity of each confirmed condition. The smaller the assessment value is when a single confirmed condition is mild, the larger the assessment value is when a single confirmed condition is severe. Then, the assessment values ​​of each confirmed condition are added together to obtain the TCM syndrome assessment value, and the TCM syndrome assessment value is not higher than 25.

[0029] In this embodiment of the invention, the data processing and analysis module performs the following operations to analyze serum growth and development: The concentration of insulin-like growth factor-1 in serum was extracted, and 5 mL of fasting venous blood was drawn in the morning for data collection. The hemoglobin level was detected by routine blood tests, and the concentration of insulin-like growth factor-1 in serum was determined by chemiluminescence technology. At the same time, growth hormone indicators were extracted from historical data, and the measured insulin-like growth factor-1 concentration was compared with the corresponding growth hormone indicators to obtain the serum growth and development assessment value. When the concentration of insulin-like growth factor-1 is lower than the growth hormone level, the serum growth and development status is deficient in growth hormone, and the serum growth and development status assessment value is 25. Conversely, when the concentration of insulin-like growth factor-1 is normal, the serum growth and development status assessment value is 0.

[0030] In this embodiment of the invention, the data processing and analysis module performs the following operations to analyze adverse reactions: Extract children's adverse reaction history and automatically compare the components of adverse reactions with the components used in the intervention program; If there are known allergens or contraindicated ingredients, a risk warning will be generated and the doctor will be informed to adjust the strategy. If there are no allergens, the current adverse reaction assessment value will be determined based on the number of adverse reactions that occur within the same period. The more times the adverse reactions occur, the higher the corresponding adverse reaction assessment value will be, and the adverse reaction assessment value will not exceed 25.

[0031] In this embodiment of the invention, the operation of comparing the clinical assessment value with the set assessment criteria table is as follows: The clinical assessment value is obtained by summing the basic parameter assessment values, TCM syndrome assessment values, serum growth and development assessment values, and adverse reaction assessment values ​​obtained from the analysis. The clinical assessment value is then compared with the assessment criteria table to determine the child's growth and development status. Based on the determination of the child's growth and development, a personalized intervention plan is generated. The intervention plan combines a liver-soothing, intelligence-enhancing, vision-improving, and height-increasing plaster with placebo therapy and massage therapy at corresponding acupoints. After the intervention, the data is extracted and re-evaluated.

[0032] Among them, the Liver-Soothing, Intelligence-Enhancing, Vision-Improving, and Height-Growth Paste is a compound preparation. It consists of 90g of Moutan Cortex, 180g of White Peony Root, 50g of Licorice Root, 100g of Poria Cocos, 100g of Fried Atractylodes Macrocephalae Rhizoma, 60g of Bupleurum Root, 120g of Chinese Dioscorea Rhizoma, 120g of Codonopsis Root, 180g of Imperata Rhizoma, 100g of Alpinia Oxyphyllae Semen, 150g of Lycium Fruit, 180g of Litchi Semen, 180g of Raw Malt, 90g of Eucommia Bark, 60g of Prunus Flower, and 180g of Ligustrum Lucidum Fruit. The excipients are 150g of Maltose and 150g of Rock Sugar. The medicinal herbs (excluding maltose and rock sugar) are soaked in water, decocted twice, and the filtrates are combined and concentrated into a clear paste. Maltose and rock sugar are then added to thicken the paste, resulting in a paste of suitable consistency.

[0033] By analyzing children's basic parameters, TCM syndromes, serum growth and development, and adverse reactions one by one, and combining the analysis results to obtain corresponding diagnostic results, clear quantitative assessment value calculation rules were set, making the assessment results standardized, measurable, and comparable. This greatly reduced the judgment bias caused by differences in doctors' experience. Furthermore, by combining the analysis of multiple factors, it effectively filled the gap in the cross-disciplinary research of "syndrome differentiation and treatment - modern pathology" in the field of growth and development delay.

[0034] Example 2 differs from Example 1 in that: the present invention also discloses a clinical assessment method for children's growth and development, specifically including the following steps: S1. Collect various data related to children's growth and development; S2. To perform data analysis and operation, combine the precise measurement of modern medicine with the holistic diagnosis of traditional Chinese medicine to assess the growth and development of children, and generate personalized intervention plans based on the assessment of children's growth and development. S3. After the child receives intervention treatment based on the personalized intervention plan, a reassessment is conducted to determine whether the child's growth and development have improved.

[0035] Please see Figure 3 The present invention also includes a set of control experiments: One hundred and fourteen children with growth retardation admitted to the cooperating hospitals within two years were selected as the study subjects. The patients were randomly divided into a control group and a study group, with 52 patients in each group. The control group (basic treatment + placebo) was expected to grow 4.0 ± 1.2 cm in height over 6 months; the study group was expected to grow 4.8 ± 1.2 cm in height over 6 months (δ = 0.8 cm, the difference was clinically significant). Considering a 10% dropout rate, each group required 52 patients, for a total of 104 patients. Furthermore, the diagnostic criteria refer to the "Chinese Journal of Pediatrics", "Revision of the Growth Standards for Children Under 7 Years Old in China", and "Screening for Malnutrition in School-Age Children and Adolescents" to formulate the diagnostic criteria for growth retardation: height is lower than the average height of children of the same age and sex -2 SD (standard deviation) or annual growth rate <5 cm / year; The diagnostic criteria refer to the diagnostic criteria for the deficiency of kidney and spleen syndrome in the Chinese Pediatric Traditional Chinese Medicine: slow growth, yellow and sparse hair, sallow complexion, thin body, irregular bowel movements, poor appetite, pale tongue with thick white coating, and weak or deep and slow pulse. Furthermore, the inclusion criteria for the subjects met the following diagnostic and diagnostic criteria: ① age 5-16 years; ② bone age delay ≥1 year (assessed by GP atlas method or TW3 method); ③ informed consent from family members and signed informed consent forms; ④ compliance with the ethical review standards in the Declaration of Helsinki. In addition, during the intervention treatment, both groups were given comprehensive nutritional supplements: Dietary guidance: eat more milk, sardines, spinach, carrots and oranges, eat a light diet, eat more soy products and nuts, and cultivate self-eating and chewing habits; Both groups received placebo therapy, including the following three points: 1. Psychological Counseling and Emotional Management: Parental Psychological Support: Monthly group counseling sessions for parents to guide them in managing anxiety and avoiding passing on height anxiety to their children. Content includes cognitive behavioral therapy (CBT) training to help parents set realistic expectations; 2. Behavioral and environmental adjustments: ① Dietary behavior correction: The nutritionist guides parents to design "fun nutritional meals" once a month to solve picky eating problems, establish regular eating habits, and avoid forced feeding. ③ Exercise incentive plan: Based on the bone age assessment results, design a combination of jumping (rope skipping, basketball) and stretching (swimming, gymnastics) exercises, 5 times a week, 30 minutes each time, and use a reward sticker system to maintain participation. 3. Family-Medical Team Collaboration: ① Establish a WeChat group for parents, push one positive parenting suggestion every day (such as "Praise your child's progress more today"), and have medical staff answer questions once a week. ② Hold a "Growth Story Sharing Session" every quarter, inviting families who have successfully received treatment to share their experiences and strengthen their confidence in treatment. Meanwhile, the research group administered a combination of liver-soothing, intelligence-enhancing, vision-improving, and height-increasing ointment with placebo therapy, and performed massage on corresponding acupoints. Next, the clinical assessment system was used to evaluate the two groups, and the differences in height-related data, TCM syndrome scores, serum growth and development indicators, adverse reactions, and the clinical effect of the combination of Shugan Yizhi Mingmu Changgao ointment and placebo therapy in the treatment of growth retardation were observed and compared. The comprehensive assessment value of the control group was greater than that of the study group. Therefore, it was found that the growth and development of children in the control group was relatively slow and accompanied by various symptoms, while the growth and development of children in the study group gradually normalized and was better than that of the control group.

[0036] Furthermore, any content not described in detail in this specification is existing technology known to those skilled in the art.

[0037] It should be noted that, in this document, relational terms such as "first" and "second" are used only to distinguish one entity or operation from another, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Furthermore, the terms "comprising," "including," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such process, method, article, or apparatus.

[0038] Although embodiments of the invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A clinical assessment system for children's growth and development, characterized in that: include: The multimodal data acquisition module collects various types of raw data related to children's growth and development, and transmits and stores the data; The data processing and analysis module receives raw data from the data acquisition module, classifies and integrates it, and analyzes the child's basic parameters, TCM syndromes, serum growth and development, and adverse reactions one by one. It combines the analysis results to obtain corresponding diagnostic results, and synthesizes the analysis results to obtain clinical assessment values. By comparing the clinical assessment values ​​with the set assessment criteria table, the current growth and development status of the child is determined. The intervention and feedback module generates personalized intervention plans based on children's growth and development, and simultaneously records the implementation of intervention measures and subsequent feedback data to form a closed loop, which is used to evaluate the intervention effect and optimize the plan.

2. The clinical assessment system for children's growth and development according to claim 1, characterized in that: The children whose data are collected by the multimodal data acquisition module must meet the following requirements: the children must be between 5 and 16 years old, all family members must have given informed consent to the collection of the children's growth and development data and have signed an informed consent form, the children must not have mental illness or cognitive impairment, and they must not be using any drugs that affect growth.

3. The clinical assessment system for children's growth and development according to claim 1, characterized in that: The data processing and analysis module receives raw data from the data acquisition module and performs classification and integration as follows: Set up an integrated table with basic parameters, TCM syndromes, serum growth and development, and adverse reactions as the main headings in the horizontal position; Furthermore, the vertical row headings starting from the third row of the first column of the integrated table are filled with the timestamps of different data collections, while the horizontal column headings starting from the second column of the second row of the integrated table are filled with the names of various categories corresponding to basic parameters, TCM syndromes, serum growth and development, and adverse reactions. The column headings are adapted to the length of multiple category names under the main heading to expand the main heading. Then, based on the category name and timestamp, the content matching operation with the collected data is completed, and the result data under the corresponding category of the collected data is filled into the table column where the category name is located and the timestamp is located.

4. A clinical assessment system for children's growth and development according to claim 3, characterized in that: The method for expanding the main title by adjusting the length of multiple category names under the main title is as follows: Set the maximum table length for a single category name to 'a', and the number of corresponding category names to 'n'. If the number of single category names does not exceed the maximum table length 'a', then the table length occupied by the single category name in real time is marked as 'b'. Conversely, if the number of single category names exceeds the maximum table length 'a', then the table length is marked as 'a', and the vertical position of the table is expanded. The expansion of the main title is achieved by summing the table length occupied by each category name under the corresponding main title, which is the length of the main title table column. If the summed main title table column length is greater than the initial main title table column length, the initial main title table column will be expanded according to the summed main title table column length, and the content of the main title table column will be centered.

5. A clinical assessment system for children's growth and development according to claim 1, characterized in that: The data processing and analysis module performs the following operations to analyze the child's basic parameters: We extract children’s weight and height data at the initial stage and subsequent cyclical time stages, and at the same time extract standard reference data of children of the same age and gender to generate normal reference intervals. 通过对同一周期时间阶段下单个儿童的同类别的多次数据结果进行提取，并根据数据结果得出平均值，再将相邻周期时间阶段下的同类别数据的变化率得出后与正常参考 区间进行比较并生成基本参数情况评估值标为cx； 比较结果为：体重变化率属于体重正常参考区间，身高变化率属于或高于身高正常参考区间，则设定当前基本参数情况评估值为c1，体重变化率属于体重正常参考区间，身 高变化率小于身高正常参考区间，则设定当前基本参数情况评估值为c2，体重变化率大于体重正常参考区间，身高变化率属于或高于身高正常参考区间，则设定当前基本参数情况 评估值为c3，体重变化率大于体重正常参考区间，身高变化率小于身高正常参考区间，则设定当前基本参数情况评估值为c4，且c1＜c3＜c2＜c4＜25。 6. A clinical assessment system for children's growth and development according to claim 5, characterized in that: The data processing and analysis module performs the following operations to analyze TCM syndromes: By matching the physical condition of children identified by TCM experts with the TCM syndrome knowledge base, and confirming whether there are conditions such as slow growth, yellowing and sparse hair, sallow complexion, thin body, irregular bowel movements and loss of appetite based on the data; At the same time, the TCM syndrome assessment value is obtained based on the severity of each confirmed condition. The smaller the assessment value is when a single confirmed condition is mild, the larger the assessment value is when a single confirmed condition is severe. Then, the assessment values ​​of each confirmed condition are added together to obtain the TCM syndrome assessment value, and the TCM syndrome assessment value is not higher than 25.

7. A clinical assessment system for children's growth and development according to claim 6, characterized in that: The data processing and analysis module includes the following operations for analyzing serum growth and development: The concentration of insulin-like growth factor-1 in serum was extracted, and 5 mL of fasting venous blood was drawn in the morning for data collection. The hemoglobin level was detected by routine blood tests, and the concentration of insulin-like growth factor-1 in serum was determined by chemiluminescence technology. At the same time, growth hormone indicators were extracted from historical data, and the measured insulin-like growth factor-1 concentration was compared with the corresponding growth hormone indicators to obtain the serum growth and development assessment value. When the concentration of insulin-like growth factor-1 is lower than the growth hormone level, the serum growth and development status is deficient in growth hormone, and the serum growth and development status assessment value is 25. Conversely, when the concentration of insulin-like growth factor-1 is normal, the serum growth and development status assessment value is 0.

8. A clinical assessment system for children's growth and development according to claim 7, characterized in that: The data processing and analysis module performs the following operations to analyze adverse reactions: Extract children's adverse reaction history and automatically compare the components of adverse reactions with the components used in the intervention program; If there are known allergens or contraindicated ingredients, a risk warning will be generated and the doctor will be informed to adjust the strategy. If there are no allergens, the current adverse reaction assessment value will be determined based on the number of adverse reactions that occur within the same period. The more times the adverse reactions occur, the higher the corresponding adverse reaction assessment value will be, and the adverse reaction assessment value will not exceed 25.

9. A clinical assessment system for children's growth and development according to claim 8, characterized in that: The operation of comparing the clinical assessment values ​​with the established assessment criteria table is as follows: The clinical assessment value is obtained by summing the basic parameter assessment values, TCM syndrome assessment values, serum growth and development assessment values, and adverse reaction assessment values ​​obtained from the analysis. The clinical assessment value is then compared with the assessment criteria table to determine the child's growth and development status. Based on the determination of the child's growth and development, a personalized intervention plan is generated. The intervention plan combines a liver-soothing, intelligence-enhancing, vision-improving, and height-increasing plaster with placebo therapy and massage therapy at corresponding acupoints. After the intervention, the data is extracted and re-evaluated.

10. A clinical assessment method for children's growth and development, employing a clinical assessment system for children's growth and development as described in any one of claims 1-9, characterized in that: Specifically, the following steps are included: S1. Collect various data related to children's growth and development; S2. To perform data analysis and operation, combine the precise measurement of modern medicine with the holistic diagnosis of traditional Chinese medicine to assess the growth and development of children, and generate personalized intervention plans based on the assessment of children's growth and development. S3. After the child receives intervention treatment based on the personalized intervention plan, a reassessment is conducted to determine whether the child's growth and development has improved, and optimization is achieved based on the assessment results.

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