Low-rate cooling control preparation device for mupirocin ointment

Abstract

The invention discloses a low-rate cooling control preparation device for mupirocin ointment, and relates to the technical field of ointment preparation. According to the scheme, the stirring device comprises a support and a tank body which is horizontally arranged on the support and provided with a jacket, the tank body comprises a movable section and fixed sections for rotationally sealing the two ends of the movable section, and the movable section can rotate around the axis of the movable section; comprising a fixed shaft, a stirring sleeve rotationally arranged outside the fixed shaft in a sleeving manner, and a plurality of blades mounted on the stirring sleeve; the driving mechanism is mounted on the bracket and is used for driving the movable section to rotate; and the synchronizing assembly is used for transmitting the rotary motion of the movable section to the stirring sleeve, so that the stirring sleeve and the movable section rotate in opposite directions. A strong two-way shear flow field is formed through autorotation of the tank body and reverse rotation of the stirrer in the tank body, so that the mixing efficiency is improved.

Description

Technical Field

[0001] This invention relates to the field of ointment preparation technology, and more particularly to a low-rate cooling controlled preparation device for mupirocin ointment. Background Technology

[0002] The preparation of mupirocin ointment requires mixing, heating, and subsequent slow cooling of the raw materials.

[0003] In the later stages of cooling, the viscosity of the material increases sharply and its fluidity deteriorates, posing a significant challenge to traditional mixing equipment. First, the stirring blades are easily coated with viscous materials, forming a "shaft-clamping" phenomenon, which leads to a sharp drop in stirring efficiency and uneven heat exchange inside the tank. Secondly, high-viscosity materials tend to adhere to the inner wall of the tank, forming an insulation layer that severely hinders heat transfer through the jacket, affecting the cooling rate and uniformity. Third, strong shearing and stirring may damage the already formed ointment structure and affect the physical stability of the product. Summary of the Invention

[0004] In view of this, the purpose of the present invention is to solve the above-mentioned problems.

[0005] To achieve the above-mentioned technical objectives, the present invention provides a low-rate cooling controlled preparation device for mupirocin ointment: It includes a support frame and a jacketed tank horizontally mounted on the support frame. The tank includes a movable section and a fixed section that provides a rotary seal at both ends. The movable section is rotatable about its own axis. It also includes: The stirring assembly is coaxially disposed inside the tank and includes a fixed shaft, a stirring sleeve rotatably sleeved outside the fixed shaft, and multiple blades mounted on the stirring sleeve. The drive mechanism, mounted on the bracket, is used to drive the movable section to rotate; A synchronization component is used to transmit the rotational motion of the moving section to the stirring sleeve, so that the stirring sleeve rotates in the opposite direction to the moving section.

[0006] Preferably, the drive mechanism includes a gear ring fixed to the outer wall of the movable section, a motor mounted on a bracket, and a drive gear mounted on the motor output shaft and meshing with the gear ring.

[0007] Preferably, the stirring assembly further includes: A fixed bevel gear is fixed to the fixed shaft, and its circumferential surface has tooth blocks distributed only within a specific angular range; The driven bevel teeth are provided for each blade and are connected to the blade drive; when the driven bevel teeth revolve with the stirring sleeve to mesh with the tooth block area of ​​the fixed bevel teeth, they drive the blade to deflect around its own axis.

[0008] Preferably, the toothed blocks are distributed such that: when the blade rotates to the lower half of the movable section, the blade deflects at an angle; when the blade rotates to the upper half of the movable section, the blade returns to its original position so that its side is parallel to the inner wall of the movable section.

[0009] Preferably, a support is fixed to the outer surface of the stirring sleeve, and a transmission seat is fixed to one end of the blade near the support, with the transmission seat rotatably connected to the support.

[0010] Preferably, it further includes a locking structure for maintaining the blade deflection angle, the locking structure comprising: A limiting ring is fixed on the transmission seat, and its end face is provided with a first wedge-shaped block; A fixing ring is fixed to the support, and its end face is provided with a second wedge block that mates with the first wedge block; A spring is used to apply a spring force to the limiting ring to engage the first wedge block with the second wedge block.

[0011] Preferably, it further includes: Driven seat, fixed to the end of the stirring sleeve; A transmission sleeve is rotatably connected to a bracket. The transmission sleeve is connected to the driven seat via a keyway to transmit torque and allow the stirring sleeve to slide axially.

[0012] Preferably, it further includes a connecting seat and a linear drive mechanism, wherein the stirring sleeve is rotatably connected to the connecting seat, and the connecting seat is slidably connected to the support; The linear drive mechanism is used to drive the connecting seat to move the stirring sleeve and blades back and forth along the axis of the tank.

[0013] Preferably, the bottom of the movable section is provided with a discharge nozzle, and a sealing gasket is fixedly fitted onto the discharge nozzle. A discharge ring is fixed on the bracket, and the discharge nozzle extends into the discharge ring and forms a rotary sliding seal with the discharge ring through the sealing gasket.

[0014] Preferably, a support wheel with an inner groove is rotatably connected to the bracket, and an annular track is fixed on the outer surface of the movable section, the annular track being fitted into the groove of the support wheel.

[0015] As can be seen from the above technical solutions, this application has the following beneficial effects: 1. By rotating the tank itself and the internal agitator in the opposite direction, a strong bidirectional shear flow field is formed, which improves the mixing efficiency; 2. The blade angle can change with position. When the blade rotates to the lower part of the tank, it is deflected by the action of the fixed and driven conical teeth, cutting into the high-viscosity material layer at an inclined angle, breaking the laminar flow state and enhancing the axial and radial tumbling ability. When the blade rotates to the upper part of the tank, it can automatically return to the center and keep parallel to the tank wall, scraping off the wall material in the best posture. Thus, it adapts to the rheological state of the material at different positions. 3. The agitator assembly can reciprocate axially, allowing the blades to continuously scrape the entire inner wall of the tank, effectively preventing material from sticking to the wall and forming a thermal resistance layer, thus ensuring the jacket heat exchange efficiency. Attached Figure Description

[0016] To more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on the provided drawings without creative effort.

[0017] Figure 1 This is a schematic diagram of the overall structure of the low-rate cooling control preparation device for mupirocin ointment provided by the present invention. Figure 2 A schematic diagram of the exploded structure of the tank of the low-rate cooling control preparation device for mupirocin ointment provided by the present invention; Figure 3 This is a schematic diagram of a partial explosion structure of the low-rate cooling control preparation device for mupirocin ointment provided by the present invention. Figure 4 A cross-sectional schematic diagram of the low-rate cooling control preparation device for mupirocin ointment provided by the present invention. Figure 5 This is a cross-sectional schematic diagram of the low-rate cooling control preparation device for mupirocin ointment provided by the present invention. Figure 6 This is an enlarged structural diagram of point A of the low-rate cooling control preparation device for mupirocin ointment provided by the present invention. Figure 7 A schematic diagram of the overall structure of the stirring assembly of the low-rate cooling control preparation device for mupirocin ointment provided by the present invention; Figure 8 A schematic diagram of the overall structure of the stirring sleeve of the low-rate cooling control preparation device for mupirocin ointment provided by the present invention; Figure 9 A partial cross-sectional view of the stirring assembly of the low-rate cooling control preparation device for mupirocin ointment provided by the present invention. Figure 10A schematic diagram of the fixed conical teeth structure of the low-rate cooling control preparation device for mupirocin ointment provided by the present invention; Figure 11 A schematic diagram of the overall structure of the drive shaft of the low-rate cooling control preparation device for mupirocin ointment provided by the present invention; Figure 12 This is a schematic diagram of the overall structure of the limiting ring and fixing ring of the low-rate cooling control preparation device for mupirocin ointment provided by the present invention.

[0018] illustrate: 10. Bracket; 11. Support wheels; 20. Tank body; 21. Fixed section; 211. Through groove; 212. Sealing pressure ring; 22. Moving section; 221. Discharge ring; 222. Discharge nozzle; 2221. Sealing gasket; 23. Toothed ring; 30. Electric motor; 31. Drive gear; 40. Synchronization component; 50. Agitator assembly; 51. Fixed shaft; 511. Fixed bevel gear; 5111. Tooth block; 52. Agitator sleeve; 521. Support; 522. Driven seat; 523. Outer flange ring; 524. Inner flange seat; 53. Blade; 531. Transmission seat; 5311. Limiting ring; 532. Limiting sleeve; 5321. Fixed ring; 54. Transmission shaft; 541. Driven bevel gear; 55. Spring; 60. Transmission sleeve; 70. Connector. Detailed Implementation

[0019] The following description is exemplary in nature and is not intended to limit the scope, application, or use of this disclosure. It should be understood that in all these figures, the same or similar reference numerals indicate the same or similar parts and features. The figures are merely schematic representations of the concept and principles of embodiments of this disclosure and do not necessarily show the specific dimensions and scale of the various embodiments of this disclosure. Certain details or structures of embodiments of this disclosure may be exaggerated in particular portions of certain figures.

[0020] Example 1, see Figures 1-12As shown, the low-rate cooling controlled preparation device for mupirocin ointment includes a support 10, a container 20, and a motor 30. Several support wheels 11 are rotatably mounted on the support 10. The container 20 is horizontally positioned and includes a movable section 22 rotatable about its own axis and a fixed section 21 that rotatably seals both ends of the movable section 22. The fixed section 21 is fixed to the support 10. An annular track is fixed to the outer surface of the movable section 22. The support wheels 11 are wheels with internal grooves, and the annular track fits into the internal grooves of the support wheels 11 to ensure… The movable section 22 is reliably supported, allowing it to rotate smoothly and preventing axial movement. A gear ring 23 is fixedly fitted on the outer wall of the movable section 22. The drive motor 30 is fixedly mounted on the bracket 10. A drive gear 31 is mounted on the output shaft of the drive motor 30. The drive gear 31 meshes with the gear ring 23. When the drive motor 30 is started, the gear ring 23 can be driven to rotate through the drive gear 31, thereby driving the entire movable section 22 to rotate around its axis, promoting the internal material to turn over, increasing the heat exchange area, and avoiding local overcooling of the material.

[0021] For further details, please refer to [link / reference]. Figure 2 , Figure 4 , Figure 5 and Figure 6 As shown, both the fixed section 21 and the movable section 22 are equipped with jackets. The jackets on the two fixed sections 21 are connected to an external circulating temperature control system (not shown in the figure) through pipelines for introducing cooling medium. A through groove 211 is provided between the fixed section 21 and the movable section 22, so that the jackets between the fixed section 21 and the movable section 22 are connected through the through groove 211, thereby forming a complete circulation channel for the jackets of the entire tank 20, ensuring uniform temperature control of the entire tank wall.

[0022] It is worth mentioning that, see Figure 2 , Figure 4 and Figure 5 As shown, one of the fixed sections 21 is provided with a feed inlet for feeding materials into the tank 20. The bottom of the movable section 22 is provided with a discharge nozzle 222. A discharge ring 221 is fixedly installed on the bracket 10. The bottom of the discharge ring 221 is connected to a discharge flange pipe. The outer wall of the discharge nozzle 222 is fitted with a sealing gasket 2221 and extends into the discharge ring 221 to form a rotational sliding seal with it. When it is necessary to discharge, the movable section 22 rotates so that the discharge nozzle 222 is aligned with the discharge flange below the discharge ring 221. The valve can be opened to discharge the viscous paste in the rotating state or the stationary state of the movable section 22. Furthermore, see Figure 6 As shown, the connection between the fixed section 21 and the movable section 22 is sealed by the sealing ring 212, which ensures that the jacket medium does not leak. In addition, the inner wall of the fixed section 21 protrudes axially and fits into the movable section 22, further ensuring the rotational sealing effect between the movable section 22 and the fixed section 21.

[0023] See Figure 7 , Figure 8 , Figure 9 , Figure 10 and Figure 11 As shown, a stirring assembly 50 is provided inside the tank 20. The stirring assembly 50 is coaxially arranged inside the tank 20. The stirring assembly 50 includes a fixed shaft 51, the two ends of which are fixed to the support 10. A stirring sleeve 52 is rotatably connected to the outer surface of the fixed shaft 51. The stirring sleeve 52 can rotate around the fixed shaft 51. On the outer wall of the stirring sleeve 52, a plurality of radial supports 521 are evenly distributed along the axial direction. Each support 521 is rotatably connected to a blade 53. A transmission seat 531 is fixedly connected to the end near the support 521. The transmission seat 531 has a spline groove inside. A transmission shaft 54 ​​is slidably connected inside the transmission seat 531. The transmission shaft 54 ​​is rotatably connected to the support 521. The transmission shaft 54 ​​and the transmission seat 531 are slidably engaged by the spline and spline groove, which allows the transmission shaft 54 ​​and the transmission seat 531 to transmit torque. The transmission seat 531 can slide axially relative to each other. A driven bevel tooth 541 is fixedly installed through the support 521 at the other end. For further details, please refer to [link / reference]. Figure 9 and Figure 10 As shown, a fixed bevel tooth 511 is fixedly installed on the fixed shaft 51, corresponding to the position of each blade 53. The circumference of the fixed bevel tooth 511 is not entirely covered with teeth, but rather has tooth blocks 5111 distributed within a specific angle range according to design requirements. The purpose is that when the stirring sleeve 52 is driven to rotate, it will drive all the blades 53 to revolve around the fixed shaft 51, thereby stirring the mupirocin ointment. During this process, each blade 53 also rotates around the fixed shaft 51 through the driven bevel tooth 541. Once the driven bevel tooth 541 rotates into the area of ​​the fixed bevel tooth 511 with tooth blocks 5111, the two will mesh. Since the fixed bevel tooth 511 is fixed, this meshing will force the driven bevel tooth 541 to rotate. The torque is transmitted to the transmission seat 531 through the transmission shaft 54 ​​and spline, thereby driving the blade 53 to deflect relative to the support 521 and change its angle. It is worth mentioning that the distribution logic of the toothed block 5111 is such that when the blade 53 rotates to the lower half of the movable section 22, it deflects at an angle so that the blade 53 obliquely cuts into the mupirocin ointment, avoiding the increased viscosity of the mupirocin ointment during the later stages of cooling, which would cause difficulties in stirring. When the blade 53 rotates to the upper half of the movable section 22, it can be deflected so that the top edge of the blade 53 is parallel to the axis of the fixed shaft 51. (See reference...) Figure 4 and Figure 5 As shown, let the blade 53 scrape off the mupirocin ointment adhering to the movable section 22.

[0024] For further details, please refer to [link / reference]. Figure 9 and Figure 12 As shown, to prevent the blade 53 from deflecting arbitrarily, a locking structure is added between the drive shaft 54 ​​and the drive seat 531. Specifically, a limiting ring 5311 is fitted outside the drive seat 531, with a first wedge-shaped block on its end face. A limiting sleeve 532 is fixed on the support 521, and a fixing ring 5321 is fixed inside the limiting sleeve 532. The end face of the fixing ring 5321 has a second wedge-shaped block that matches the first wedge-shaped block. A spring 55 is provided between the limiting ring 5311 and the drive shaft 54. The spring 55 is fitted on the drive shaft 54, and its two ends abut against the drive shaft 54 ​​and the limiting ring 5311, respectively. The spring 55 drives the drive shaft 54 ​​through its elastic force. The second and first wedge blocks on the limiting ring 5311 and the fixed ring 5321 are engaged and locked. The blade 53 will only start to deflect when the torque transmitted by the drive shaft 54 ​​for twisting the blade 53 is sufficient to overcome the preload of the spring 55 and the friction of the second and first wedge blocks. Once the torque decreases, the second and first wedge blocks re-engage and lock under the action of the spring 55, so that the blade 53 is stable at a new angle. In this way, the blade 53 can stably cut into the mupirocin ointment when rotating to the area with high resistance in the lower half of the moving section 22, ensuring the stirring effect, and can stably scrape the wall parallel to the wall when rotating to the upper half of the moving section 22.

[0025] Furthermore, to generate stronger shear by counter-rotating the active section 22 and the internal stirring assembly 50, a synchronization assembly 40 is also included. The synchronization assembly 40 consists of sprockets, chains, and gear sets; specific details are not provided here, but please refer to [reference needed]. Figure 3 As shown, it transmits the rotational motion of the toothed ring 23 of the moving section 22 to the stirring sleeve 52, ensuring that the two speeds match and their directions are opposite.

[0026] Example 2, based on the above examples, a low-rate cooling control preparation device for mupirocin ointment further includes a connecting seat 70. To further improve the comprehensiveness of wall scraping, the stirring sleeve 52 is designed to be axially movable. The stirring sleeve 52 is rotatably connected to the connecting seat 70, and the connecting seat 70 is slidably connected to the support 10. A linear drive mechanism is installed on the connecting seat 70. The linear drive mechanism is such as an electric push rod or a lead screw slide module, which is not specifically limited here. When the drive mechanism is activated, the entire connecting seat 70 can be driven to reciprocate along the axial direction of the movable section 22 with the stirring sleeve 52. This allows the wall scraping action of the limited number of blades 53 to cover the entire inner wall surface of the tank 20.

[0027] It is worth mentioning that, in order to ensure that the stirring sleeve 52 reciprocates along the axis of the movable section 22 without affecting the rotation of the stirring sleeve 52, the end of the stirring sleeve 52 is provided with an outer flange ring 523 and an inner flange seat 524. The stirring sleeve 52 is connected to a driven seat 522 through the outer flange ring 523 and the inner flange seat 524. A transmission sleeve 60 is fitted on the outer surface of the driven seat 522. The two are connected by a keyway and a key, which satisfies the requirement that the stirring sleeve 52 can slide axially while transmitting torque, and the stirring sleeve 52 can translate along its axis.

[0028] Specifically, the transmission sleeve 60 is mounted on the bracket 10 via bearings, and the output part of the synchronization component 40 is mounted on the transmission sleeve 60. For example, the output sprocket in the synchronization component 40 is fixed on the transmission sleeve 60, and the input sprocket in the synchronization component 40 is driven by the output sprocket via a chain. The input sprocket is also coaxially connected to a driven gear that meshes with the gear ring 23, so as to obtain power through the synchronization component 40.

[0029] For example, the material is fed into the movable section 22 from the feed port of the fixed section 21. The external temperature control system introduces cooling medium into the jacket and starts the motor 30 at the same time, so that the movable section 22 and the stirring sleeve 52 rotate in opposite directions and at low speed. The rotation of the movable section 22 drives the material to flow as a whole, while the blades 53, which rotate in the opposite direction and can move axially back and forth, efficiently shear, turn and scrape the material and clean the wall surface, so that the viscous mupirocin ointment semi-finished product in the tank can be cooled evenly and at low speed. After cooling is completed, it is discharged through the discharge nozzle 222.

[0030] The exemplary implementation of the solution proposed in this disclosure has been described in detail above with reference to preferred embodiments. However, those skilled in the art will understand that various modifications and alterations can be made to the above specific embodiments without departing from the spirit of this disclosure, and various combinations can be made to the various technical features and structures proposed in this disclosure without exceeding the protection scope of this disclosure, which is determined by the appended claims.

Claims

1. A low-rate cooling controlled preparation apparatus for mupirocin ointment, comprising a support (10) and a jacketed container (20) horizontally placed on the support (10), characterized in that, The tank body (20) includes a movable section (22) and a fixed section (21) for rotating sealing at both ends thereof. The movable section (22) can rotate about its own axis and also includes: The stirring assembly (50) is coaxially disposed inside the tank (20) and includes a fixed shaft (51), a stirring sleeve (52) rotatably sleeved outside the fixed shaft (51), and multiple blades (53) mounted on the stirring sleeve (52). The drive mechanism, mounted on the bracket (10), is used to drive the movable section (22) to rotate; Synchronization component (40) is used to transmit the rotational motion of the moving section (22) to the stirring sleeve (52), so that the stirring sleeve (52) and the moving section (22) rotate in opposite directions.

2. The low-rate cooling controlled preparation device for mupirocin ointment according to claim 1, characterized in that, The drive mechanism includes a gear ring (23) fixed to the outer wall of the movable section (22), a motor (30) mounted on the bracket (10), and a drive gear (31) mounted on the output shaft of the motor (30) and meshing with the gear ring (23).

3. The low-rate cooling controlled preparation device for mupirocin ointment according to claim 1, characterized in that, The stirring assembly (50) further includes: A fixed bevel tooth (511) is fixed on the fixed shaft (51), and its circumferential surface has tooth blocks (5111) distributed only within a specific angular range. Driven bevel teeth (541) are provided for each blade (53) and are connected to the blade (53) in a transmission manner; when the driven bevel teeth (541) revolve with the stirring sleeve (52) to mesh with the tooth block (5111) area of ​​the fixed bevel teeth (511), they drive the blade (53) to deflect around its own axis.

4. The low-rate cooling controlled preparation device for mupirocin ointment according to claim 3, characterized in that, The distribution of the toothed blocks (5111) is such that when the blade (53) rotates to the lower half of the movable section (22), the blade (53) deflects at an angle; when the blade (53) rotates to the upper half of the movable section (22), the blade (53) returns to its original position so that its side is parallel to the inner wall of the movable section (22).

5. The low-rate cooling controlled preparation device for mupirocin ointment according to claim 3, characterized in that, The outer surface of the stirring sleeve (52) is fixed with a support (521), and the end of the blade (53) near the support (521) is fixed with a transmission seat (531), which is rotatably connected to the support (521).

6. The low-rate cooling controlled preparation apparatus for mupirocin ointment according to claim 4, characterized in that, It also includes a locking structure for maintaining the deflection angle of the blade (53), the locking structure comprising: The limiting ring (5311) is fixed on the transmission seat (531), and its end face is provided with a first wedge block; A fixing ring (5321) is fixed on a support (521), and its end face is provided with a second wedge block that cooperates with the first wedge block; A spring (55) is used to apply a spring force to the limiting ring (5311) to engage the first wedge block with the second wedge block.

7. The low-rate cooling controlled preparation apparatus for mupirocin ointment according to claim 1, characterized in that, Also includes: Driven seat (522) is fixed to the end of stirring sleeve (52); The transmission sleeve (60) is rotatably connected to the bracket (10). The transmission sleeve (60) and the driven seat (522) are connected by a keyway to transmit torque and allow the stirring sleeve (52) to slide axially.

8. The low-rate cooling controlled preparation apparatus for mupirocin ointment according to claim 7, characterized in that, It also includes a connecting seat (70) and a linear drive mechanism, wherein the stirring sleeve (52) is rotatably connected to the connecting seat (70), and the connecting seat (70) is slidably connected to the bracket (10); The linear drive mechanism is used to drive the connecting seat (70) to drive the stirring sleeve (52) and blades (53) to reciprocate along the axial direction of the tank (20).

9. The low-rate cooling controlled preparation apparatus for mupirocin ointment according to claim 1, characterized in that, The bottom of the movable section (22) is provided with a discharge nozzle (222), and a sealing gasket (2221) is fixedly attached to the discharge nozzle (222). A discharge ring (221) is fixed on the bracket (10). The discharge nozzle (222) extends into the discharge ring (221) and forms a rotary sliding seal with the discharge ring (221) through the sealing gasket (2221).

10. The low-rate cooling controlled preparation apparatus for mupirocin ointment according to claim 1, characterized in that, The bracket (10) is rotatably connected to a support wheel (11) with an inner groove, and the outer surface of the movable section (22) is fixed with an annular track, which is fitted into the groove of the support wheel (11).

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