Prescription for vegetative people

Abstract

According to the formula, blood circulation promoting and stasis removing medicinal materials such as pseudo-ginseng, the root of red-rooted salvia, raw hawthorn peel and the like are used for improving brain blood circulation, eliminating meridian blockage and creating good conditions for nerve cell repair; the functions of viscera are regulated by virtue of spleen-invigorating and qi-replenishing medicinal materials such as codonopsis pilosula, roasted rhizoma atractylodis macrocephalae and fresh Chinese yam and yin-enriching and kidney-tonifying medicinal materials such as radix rehmanniae preparata and fructus lycii, and the healthy qi of the body is enhanced; multi-dimensional improvement is realized through combination of medicinal materials with different effects, such as radix scrophulariae and dried radish slices, herba asari and lumbricus for dispelling wind and dredging collaterals, rhizoma anemones altaicae and polygala tenuifolia for inducing resuscitation and inducing resuscitation; the composition pays attention to overall and local combination, has the basic functions of digestion-promoting spleen and stomach regulation of endothelium corneum gigeriae galli and malt, kidney-tonifying and nerve-calming liver and kidney nourishing of schisandra chinensis and pulp of dogwood fruit and the like while improving brain symptoms, and lays a foundation for long-term rehabilitation of wakened vegetative people; the raw materials are wide in source and relatively simple and convenient to prepare, most of the medicinal materials in the formula are common traditional Chinese medicinal materials and are easy to obtain, no special processing technology is adopted, and clinical application and popularization are facilitated.

Description

Technical Field

[0001] This invention relates to the field of traditional Chinese medicine prescription technology, specifically to prescriptions for patients in a vegetative state. Background Technology

[0002] A vegetative state, medically termed a persistent vegetative state, is a specific condition characterized by impaired consciousness. Patients lose consciousness, are unable to move independently, and require external support to maintain basic life functions. The Five Elements theory is an important component of traditional Chinese philosophy, based on the principles of mutual generation and restraint among the five elements of metal, wood, water, fire, and earth in nature. The human body is closely connected to the Five Elements; in disease treatment, the theory of Yin and Yang and the Five Elements can be applied to regulate the condition—for example, using warming Chinese medicine to invigorate Yang energy; for those with Yin-Yang imbalance, restoring balance through medications that regulate Yin and Yang; and following the principle of "tonifying the mother element when deficient" to promote the circulation of Qi and blood, thus aiding in the recovery of consciousness in vegetative state patients.

[0003] The correspondence between the five internal organs and the five elements is as follows: the liver belongs to wood, the heart to fire, the spleen to earth, the lungs to metal, and the kidneys to water. The correspondence between the six viscera is as follows: the gallbladder belongs to wood, the small intestine to fire, the stomach to earth, the large intestine to metal, and the bladder to water.

[0004] Traditional Chinese medicine's understanding of vegetative state is also based on the theory of Yin and Yang and the Five Elements. It believes that the core pathogenesis is an imbalance of Yin and Yang and malnourishment of the internal organs, specifically manifested as loss of spirit, obstruction of the sensory orifices, blockage of meridians, and deficiency of Qi and blood. Among these, obstruction of the middle Jiao, stagnation of lung Qi, and constipation of the stomach and intestines can lead to the inability to expel waste products from the body in a timely manner. This waste Qi rises to the sensory orifices and has difficulty circulating downwards. If it lingers in the brain for a long time, it will form phlegm and dampness stagnation, obstructing the flow of Qi and blood, eventually leading to loss of consciousness, disuse of limbs, loss of consciousness, and the development of a vegetative state.

[0005] In summary, the root cause of vegetative state lies in the imbalance of Yin and Yang, insufficient vital energy, and malnourishment of the brain, often caused by accumulated damage, overwork, and spleen dysfunction that deplete vital energy. Traditional Chinese medicine treats vegetative state based on the theory of holistic human health, promoting the recovery of consciousness and improvement of bodily functions by harmonizing Yin and Yang, clearing the meridians, and regulating the internal organs.

[0006] I. Awakening the Mind and Opening the Orifices: Traditional Chinese medicine believes that vegetative state is mostly caused by loss of mental function and blockage of the brain orifices. The primary principle of treatment is to awaken the mind and open the orifices, and drugs with the effect of opening the orifices and awakening the mind should be selected.

[0007] II. Nourishing Qi and Blood: Prolonged illness and physical weakness, as well as insufficient Qi and blood, are common pathological states in vegetative state patients. Qi is the commander of blood, and blood is the mother of Qi. Deficiency of Qi and blood can lead to malnourishment of the brain and impaired mental function. Therefore, nourishing Qi and blood is a key aspect of treatment.

[0008] Third, clearing phlegm and unblocking the meridians: Phlegm and blood stasis obstructing the brain's orifices are one of the main causes of coma in vegetative state patients. The method of clearing phlegm and unblocking the meridians can remove phlegm and blood stasis from the body, improve cerebral blood circulation, and restore the clarity of the brain's orifices.

[0009] IV. Nourishing the Liver and Kidneys: The liver and kidneys share a common origin; deficiency of the liver and kidneys, and imbalance of Yin and Yang, can lead to insufficient brain marrow and malnourishment of the spirit. For patients with a long course of illness and liver and kidney deficiency, nourishing the Yin of the liver and kidneys, replenishing the essence of the liver and kidneys, and improving the nutritional supply to the brain are particularly important. Therefore, this invention provides a prescription for vegetative state patients. Summary of the Invention

[0010] In view of the shortcomings of the prior art, the present invention provides a prescription for vegetative state patients to solve the above problems.

[0011] To achieve the above objectives, the present invention provides the following technical solution: a prescription for vegetative state patients, comprising the following ingredients by weight:

[0012] Angelica sinensis 50g, Trichosanthes kirilowii 50g, Achyranthes bidentata 290g, Achyranthes bidentata 70g, Pheretima aspergillum 200g, Eupolyphaga sinensis 100g, Ostrea gigas 200g, Os draconis 100g, Scrophularia ningpoensis 100g, Bombyx mori 20g, Saposhnikovia divaricata 60g, Hematite 200g, Sophora japonica leaves 200g, Salvia miltiorrhiza 240g, Ligusticum chuanxiong 50g, Asarum sieboldii 20g, Rehmannia glutinosa 100g, Rehmannia glutinosa (processed) 200g Chicken gizzard lining 120g, Glauber's salt 100g, malt 30g, Artemisia capillaris 30g, Sichuan pepper 50g, Euryale ferox 100g, Asparagus cochinchinensis 80g, Nardostachys chinensis 50g, Coptis chinensis 10g, processed Strychnos nux-vomica 0.33g, Cornus officinalis 100g, Anemarrhena asphodeloides 100g, raw Platycladus orientalis 45g, Clematis chinensis 20g, raw Crataegus pinnatifida peel 300g, Panax notoginseng 300g, white peony root 10g, red peony root 100g 80g of Moutan bark, 150g of walnut kernels, 50g of raw licorice root, 30g of Acorus tatarinowii rhizome, 30g of Tetrapanax papyriferus pith, 30g of Akebia quinata root, 40g of Schisandra chinensis fruit, 120g of raw magnetite, 100g of Cynanchum paniculatum root, 30g of borax, 100g of fresh purslane, 200g of Gastrodia elata rhizome, 20g of Notopterygium incisum root, 50g of Polygala tenuifolia root, 20g of Angelica pubescens root, 120g of raw gypsum, 180g of wolfberry fruit, and 120g of Lycopodium clavatum root. 100g of Clematis armandii, 100g of Scutellaria baicalensis, 100g of Phellodendron chinense, 80g of Convolvulus arvense, 30g of Sophora flavescens, 50g of Dipsacus asper, 160g of Cuscuta chinensis, 50g of Codonopsis pilosula, 80g of Atractylodes macrocephala (fried), 150g of Dioscorea opposita (fresh), 200g of Haliotis diversicolor, 40g of Alisma plantago-aquatica, 50g of Morus alba (green mulberry leaf), 60g of Ligustrum lucidum (nu zi), 200g of dried radish slices, 50g of Psoralea corylifolia, 50g of Epimedium brevicornu, and 60g of Plantago asiatica.

[0013] Preferably, it also includes: dried ginger, rhubarb and 7 slices of fresh ginger.

[0014] Preferably, the rhubarb is ground into powder to make rhubarb powder.

[0015] The preferred ingredients also include: 10 jujubes, 10 elm seeds, 10 mulberries, and 10 purple raspberries.

[0016] Preferably, the Convolvulus is prepared in a ratio of 3:1 of fresh Convolvulus and Convolvulus paste, wherein 60g of fresh Convolvulus and 20g of Convolvulus paste are used.

[0017] Preferably, the method for preparing the vegetative state prescription includes the following steps:

[0018] Step 1: Raw material pretreatment: Prepare the following ingredients: Angelica sinensis, Trichosanthes kirilowii, Achyranthes bidentata, Achyranthes bidentata, Pheretima aspergillum, Eupolyphaga sinensis, raw oyster shell, raw dragon bone, Scrophularia ningpoensis, Bombyx batryticatus, Saposhnikovia divaricata, Hematite, Sophora japonica leaves, Salvia miltiorrhiza, Ligusticum chuanxiong, Asarum heterotropoides, Rehmannia glutinosa (raw and processed), chicken gizzard lining, Glauber's salt, malt, Artemisia capillaris, Melia toosendan, Euryale ferox, Asparagus cochinchinensis, Nardostachys chinensis, Coptis chinensis, Strychnos nux-vomica (processed), Cornus officinalis, Anemarrhena asphodeloides, Platycladus orientalis, Clematis chinensis, Crataegus pinnatifida peel, Panax notoginseng, Paeonia lactiflora, Paeonia suffruticosa, Paeonia suffruticosa, walnut kernel, raw licorice root, Acorus tatarinowii, Tetrapanax papyriferus, Akebia trifoliata, Schisandra chinensis, raw magnetite, Cynanchum paniculatum, borax, fresh Portulaca oleracea, Gastrodia elata, and Notopterygium incisum. The following ingredients are selected, washed, and dried: Polygala tenuifolia, Angelica pubescens, Gypsum fibrosum, Lycium barbarum, Lycopodium clavatum, Clematis chinensis, Scutellaria baicalensis, Phellodendron chinense, Convolvulus arvense, Sophora flavescens, Dipsacus asper, Cuscuta chinensis, Codonopsis pilosula, Atractylodes macrocephala (fried), Dioscorea opposita, Haliotis diversicolor, Alisma plantago-aquatica, Morus alba leaves, Ligustrum lucidum, dried radish slices, Psoralea corylifolia, Epimedium brevicornu, Plantago asiatica, and optional ingredients such as dried ginger, rhubarb, fresh ginger, jujube, Elm seeds, mulberry, and Rubus idaeus. Fresh ingredients such as fresh purslane, fresh yam, fresh ginger, and fresh Convolvulus arvense need to be vacuum dried at low temperature until the moisture content is ≤8% to maintain the stability of the active ingredients.

[0019] Step 2: Raw Material Classification and Pulverization: The dried raw materials are classified into three categories according to their medicinal properties: mineral raw materials, animal raw materials, and plant raw materials. The mineral raw materials include raw oyster shell, raw dragon bone, red ochre, borax, raw magnetite, raw gypsum, and abalone shell. The animal raw materials include earthworm, ground beetle, chicken gizzard lining, processed strychnine, gastrodia, and silkworm. The plant raw materials include angelica, trichosanthes root, achyranthes root, Sichuan achyranthes root, scrophularia root, saposhnikovia root, locust leaf, salvia root, chuanxiong rhizome, asarum, raw rehmannia root, prepared rehmannia root, mirabilite, malt, artemisia capillaris, Sichuan chinaberry, euryale seed, asparagus root, nardostachys root, coptis root, and yam. Cornus officinalis, Anemarrhena asphodeloides, Platycladus orientalis seeds, Clematis chinensis, Crataegus pinnatifida peel, Panax notoginseng, Paeonia lactiflora, Paeonia veitchii, Paeonia suffruticosa, walnut kernels, Glycyrrhiza uralensis, Acorus tatarinowii, Tetrapanax papyriferus, Akebia trifoliata, Schisandra chinensis, Cynanchum paniculatum, dried fresh Portulaca oleracea, Notopterygium incisum, Polygala tenuifolia, Angelica pubescens, Lycium barbarum, Lycopodium clavatum, Clematis armandii, Scutellaria baicalensis, Phellodendron chinense, dried Convolvulus arvense, Sophora flavescens, Dipsacus asper, Cuscuta chinensis, Codonopsis pilosula, stir-fried Atractylodes macrocephala, dried fresh Dioscorea opposita, Alisma plantago-aquatica, Morus alba leaves, Ligustrum lucidum, dried radish slices, Psoralea corylifolia, Epimedium brevicornu, Plantago asiatica, and optional additions such as dried ginger, rhubarb, dried fresh ginger, jujube, Elm seeds, mulberry, and raspberry.

[0020] Step 3, Raw Material Crushing: Select the crushing method according to the characteristics of different types of raw materials. Among them, the mineral raw materials are crushed by air jet milling to a particle size ≤10μm to form ultrafine mineral powder; the animal raw materials are crushed by cryogenic freezing to a particle size ≤15μm; and the plant raw materials are processed by ultrafine crushing technology to a particle size ≤20μm.

[0021] Step 4, Dynamic Extraction: Mix the three types of raw materials after crushing evenly according to the prescription ratio, put them into the dynamic extraction equipment, add 8-12 times the amount of purified water as the extraction solvent, and perform the first extraction; after filtering and collecting the first extract, add 6-8 times the amount of purified water to the residue again, and repeat the above extraction operation twice; combine the three extracts for later use.

[0022] Step 5, solid-liquid separation: The combined extract is filtered through a plate and frame filter press to remove the filter residue. The filtrate is then finely filtered through a microporous membrane to obtain the separated solid and liquid drug solutions.

[0023] Step 6, Concentration: The filtered liquid is concentrated into a thick paste using a vacuum concentration device;

[0024] Step 7, Granulation preparation: Mix the concentrated paste with dextrin evenly to form a soft material, granulate it with the first sieve, place the wet granules in a low temperature drying oven to dry until the moisture content is ≤5%, and then granulate them through the second sieve to obtain uniform intermediate granules.

[0025] Step 8, Post-processing: The intermediate particles are ultra-finely pulverized to a particle size ≤10μm to prepare the target powder, and the powder is sterilized by irradiation.

[0026] Step 9, Packaging: Finally, package the product into aluminum-plastic composite bags or pharmaceutical glass bottles in 5g per bag or 100g per bottle, seal the packaging, and affix labels containing information such as product name, ingredients, specifications, production date, and shelf life. Store the product in a cool, dry place.

[0027] Preferably, the dynamic extraction device is set to an extraction temperature of 65-75℃, a first extraction time of 90 minutes, and a subsequent two extraction times of 60 minutes.

[0028] Preferably, the vacuum degree of the vacuum concentration device is 0.08-0.09 MPa, the temperature is 55℃±5℃, and the relative density of the concentrated product is 1.25-1.30.

[0029] Preferably, the mass ratio of the concentrated paste to dextrin is 1:0.8, the first sieve is an 18-mesh sieve, the temperature of the low-temperature drying oven is 45°C, and the second sieve is a 20-mesh sieve.

[0030] A method of using a prescription for vegetative state patients, comprising any of the above-mentioned prescriptions for vegetative state patients, decocted in water and taken orally, one dose per day, once in the morning and once in the evening.

[0031] Beneficial effects

[0032] Compared with the prior art, the present invention has the following advantages:

[0033] 1. The formula is comprehensive, taking into account both strengthening the body's resistance and eliminating pathogens. It improves cerebral blood circulation and eliminates meridian blockages by using blood-activating and stasis-removing herbs such as Panax notoginseng, Salvia miltiorrhiza, and raw hawthorn peel, creating favorable conditions for nerve cell repair. It also uses spleen-strengthening and qi-tonifying herbs such as Codonopsis pilosula, stir-fried Atractylodes macrocephala, and fresh yam, as well as yin-nourishing and kidney-tonifying herbs such as Rehmannia glutinosa and wolfberry to regulate organ function and enhance the body's resistance. This solves the shortcomings of existing technologies that only target local symptoms and neglect overall functional regulation.

[0034] 2. Multi-target synergistic effect: Targeting various problems in the vegetative state such as blood viscosity, constipation, limb numbness, and confusion, it achieves multi-dimensional improvement through the combination of different medicinal materials with different effects, such as Scrophularia and dried radish slices to lubricate the intestines and promote bowel movement, Asarum and earthworm to dispel wind and unblock the meridians, and Acorus tatarinowii and Polygala tenuifolia to open the orifices and awaken the mind. Compared with the single-target effect of existing technologies, it can more effectively promote the awakening of nerve function and the comprehensive rehabilitation of physical functions.

[0035] 3. Safety is controllable. The processed nux vomica is used in a very small dose (0.33g), which can exert the effect of clearing the meridians and dispersing nodules, while strictly controlling the risk of toxicity. At the same time, raw licorice harmonizes the various medicines, reduces the bias of the medicinal materials, ensures the safety of medication, and overcomes the problem of side effects caused by drug toxicity or improper dosage in some existing therapies.

[0036] 4. It emphasizes the combination of holistic and local approaches. While improving brain symptoms, it also takes into account the spleen and stomach regulation of chicken gizzard and malt to promote digestion, and the liver and kidney nourishment of schisandra and cornus officinalis to tonify the kidneys and calm the mind. This lays the foundation for the long-term rehabilitation of vegetative patients after awakening. Compared with existing technologies, it is more systematic and long-term.

[0037] 5. The raw materials are widely available and the preparation is relatively simple. Most of the medicinal materials in the formula are common Chinese medicinal materials that are easy to obtain. They do not use special processing techniques, which facilitates clinical promotion and application. This solves the problem of insufficient popularity of some existing high-end therapies due to the scarcity of raw materials or the complexity of processes. Detailed Implementation

[0038] The technical solutions in the embodiments of the present invention will be clearly and completely described below. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0039] The prescription for vegetative state patients includes the following ingredients by weight:

[0040] Angelica sinensis 50g, Trichosanthes kirilowii 50g, Achyranthes bidentata 290g, Achyranthes bidentata 70g, Pheretima aspergillum 200g, Eupolyphaga sinensis 100g, Ostrea gigas 200g, Os draconis 100g, Scrophularia ningpoensis 100g, Bombyx mori 20g, Saposhnikovia divaricata 60g, Hematite 200g, Sophora japonica leaves 200g, Salvia miltiorrhiza 240g, Ligusticum chuanxiong 50g, Asarum sieboldii 20g, Rehmannia glutinosa 100g, Rehmannia glutinosa (processed) 200g Chicken gizzard lining 120g, Glauber's salt 100g, malt 30g, Artemisia capillaris 30g, Sichuan pepper 50g, Euryale ferox 100g, Asparagus cochinchinensis 80g, Nardostachys chinensis 50g, Coptis chinensis 10g, processed Strychnos nux-vomica 0.33g, Cornus officinalis 100g, Anemarrhena asphodeloides 100g, raw Platycladus orientalis 45g, Clematis chinensis 20g, raw Crataegus pinnatifida peel 300g, Panax notoginseng 300g, white peony root 10g, red peony root 100g 80g of Moutan bark, 150g of walnut kernels, 50g of raw licorice root, 30g of Acorus tatarinowii rhizome, 30g of Tetrapanax papyriferus pith, 30g of Akebia quinata root, 40g of Schisandra chinensis fruit, 120g of raw magnetite, 100g of Cynanchum paniculatum root, 30g of borax, 100g of fresh purslane, 200g of Gastrodia elata rhizome, 20g of Notopterygium incisum root, 50g of Polygala tenuifolia root, 20g of Angelica pubescens root, 120g of raw gypsum, 180g of wolfberry fruit, and 120g of Lycopodium clavatum root. 100g of Clematis armandii, 100g of Scutellaria baicalensis, 100g of Phellodendron chinense, 80g of Convolvulus arvense, 30g of Sophora flavescens, 50g of Dipsacus asper, 160g of Cuscuta chinensis, 50g of Codonopsis pilosula, 80g of Atractylodes macrocephala (fried), 150g of Dioscorea opposita (fresh), 200g of Haliotis diversicolor, 40g of Alisma plantago-aquatica, 50g of Morus alba (green mulberry leaf), 60g of Ligustrum lucidum (nu zi), 200g of dried radish slices, 50g of Psoralea corylifolia, 50g of Epimedium brevicornu, and 60g of Plantago asiatica.

[0041] Specifically, it also includes: dried ginger, rhubarb, and 7 slices of fresh ginger.

[0042] Specifically, rhubarb is ground into powder to make rhubarb powder.

[0043] Specifically, it also includes 10 each of jujubes, elm seeds, mulberries, and purple raspberries.

[0044] Specifically, the ingredients are prepared in a 3:1 ratio of fresh Convolvulia flowers to Convolvulia paste, with 60g of fresh Convolvulia flowers and 20g of Convolvulia paste.

[0045] Panax notoginseng and hawthorn promote blood circulation, remove blood stasis, regulate qi, and relieve pain. They promote blood circulation without leaving blood stasis, thus solving the problem of thick blood.

[0046] Both Sichuan Achyranthes bidentata and Huai Achyranthes bidentata promote blood circulation, remove blood stasis, and unblock meridians, with an emphasis on guiding blood downwards.

[0047] Scrophularia, dried radish slices, and Convolvulus arvense clear heat and cool the blood, nourish yin, reduce fire and detoxify, moisten the intestines and promote bowel movements, thus solving constipation problems;

[0048] Chicken gizzard lining and Glauber's salt purge and eliminate stagnation, clearing away urinary tract stones;

[0049] Raw oysters, raw dragon bones, and cornelian cherry can calm the liver and subdue yang, astringe and consolidate, and retain the body's vital energy without retaining pathogenic factors.

[0050] Coptis chinensis and raw cypress seeds clear heat and detoxify, and are primarily used to clear heart fire.

[0051] Nardostachys chinensis and processed strychnos nux-vomica regulate qi, relieve depression, clear the meridians, disperse stagnation, and restore heart function;

[0052] Asarum and earthworm dispel wind, clear the orifices, unblock the meridians and collaterals, and eliminate numbness of the limbs;

[0053] Nine-jointed calamus and tetrapanax papyriferus resolve dampness and phlegm, and open the orifices and refresh the mind;

[0054] Codonopsis pilosula, fresh yam, and stir-fried Atractylodes macrocephala are all mild and complementary in nature, and are used to invigorate the spleen and replenish qi, and regulate the spleen and stomach.

[0055] White peony root and red peony root calm the liver and extinguish wind, suppress liver yang, and are used to regulate the liver;

[0056] Schisandra chinensis has astringent and consolidating properties, and also tonifies the kidneys and calms the mind.

[0057] Raw magnetite calms the liver and subdues yang, assists the kidneys in astringing lung qi, and expels turbid qi from the internal organs;

[0058] Earthworm and Asarum dispel wind and open the orifices, unblock the meridians, eliminate blockages, and resolve numbness in the limbs;

[0059] Angelica sinensis has the effects of nourishing blood, promoting blood circulation, regulating menstruation and relieving pain, and moistening dryness and lubricating the intestines.

[0060] Trichosanthes kirilowii has the effects of clearing heat and purging fire, promoting body fluid and quenching thirst, reducing swelling and draining pus;

[0061] Earthworm has the effects of breaking up blood stasis, promoting tendon and bone healing, reducing swelling and relieving pain, promoting lactation, removing blood stasis, clearing menstruation, and clearing blood vessels;

[0062] Silkworm has the effects of calming wind and relieving spasms, dispelling wind and relieving pain, and resolving phlegm and dissipating nodules;

[0063] Fangfeng has the effects of dispelling wind and relieving exterior syndromes, eliminating dampness and relieving pain, and stopping spasms;

[0064] Hematite is bitter and cold in nature, and it can calm the liver, subdue yang, and suppress adverse qi.

[0065] Black locust leaves can clear heat and detoxify, promote diuresis and eliminate dampness, and lower blood pressure;

[0066] Salvia miltiorrhiza has the effects of promoting blood circulation and removing blood stasis, regulating menstruation and relieving pain, clearing the mind and relieving irritability, cooling the blood and reducing swelling.

[0067] Chuanxiong has the effects of promoting blood circulation, regulating qi, dispelling wind, and relieving pain;

[0068] Rehmannia glutinosa clears heat and cools the blood, nourishes yin and promotes the production of body fluids;

[0069] Rehmannia glutinosa has the effects of nourishing blood, nourishing yin, and replenishing essence and marrow;

[0070] Malt has the effects of promoting digestion, strengthening the spleen and stomach, and reducing lactation and bloating;

[0071] Artemisia capillaris has a bitter taste and slightly cold properties. It has a fragrant aroma and can clear away damp heat.

[0072] Sichuan pepper has the effects of soothing the liver and relieving heat, regulating qi and relieving pain;

[0073] Euryale ferox has the effects of tonifying the kidneys and securing essence, strengthening the spleen and stopping diarrhea, eliminating dampness and stopping leukorrhea, nourishing yin and moistening dryness, clearing the lungs and promoting body fluid production;

[0074] Anemarrhena asphodeloides is cold in nature and bitter in taste. It enters the lung, stomach and kidney meridians and has the effects of clearing heat and purging fire, generating fluids and moistening dryness.

[0075] Clematis chinensis has the effects of dispelling wind and dampness, clearing the meridians, relieving pain, dissolving fish bones stuck in the throat, and detoxifying and dispersing nodules;

[0076] Raw hawthorn peel has the effects of aiding digestion, strengthening the stomach, promoting qi circulation, removing blood stasis, clearing turbidity, and lowering lipids;

[0077] Moutan bark clears heat and cools the blood, promotes blood circulation and removes blood stasis;

[0078] Walnut kernels can be used to treat kidney deficiency, insufficient kidney essence, to moisten the intestines and relieve constipation, and to nourish the lungs and kidneys.

[0079] Raw licorice has many effects and functions, such as tonifying qi and strengthening the spleen, clearing heat and detoxifying, resolving phlegm and relieving cough, relieving spasms and pain, and harmonizing various medicines.

[0080] Akebia has the effects of promoting diuresis, relieving strangury, clearing the mind and relieving irritability, and promoting menstruation and lactation.

[0081] White peony root has the effects of nourishing blood and regulating menstruation, astringing yin and stopping sweating, softening the liver and relieving pain, and calming liver yang.

[0082] Borax has the effects of clearing heat and detoxifying, reducing swelling and preventing decay, clearing the lungs and resolving phlegm;

[0083] Fresh purslane has the effects of clearing heat and detoxifying, promoting diuresis and relieving strangury, and antibacterial and anti-inflammatory properties.

[0084] Gastrodia elata has the effects of calming wind and stopping spasms, suppressing liver yang, and dispelling wind and unblocking collaterals;

[0085] Notopterygium root has the effects of relieving exterior syndromes and dispelling cold, dispelling wind and dampness, and relieving pain;

[0086] Polygala tenuifolia has the effects of calming the mind and improving intelligence, reducing swelling, eliminating phlegm, and relieving depression;

[0087] Angelica pubescens has the effects of dispelling wind and dampness, relieving pain and numbness;

[0088] Gypsum has the effects and functions of clearing heat and purging fire, relieving irritability and quenching thirst, astringing and promoting tissue regeneration, treating lung heat and cough, cooling blood and stopping bleeding;

[0089] Goji berries nourish yin and kidneys, clear the liver and improve eyesight, moisten the lungs and relieve cough;

[0090] The effects of *Shenjincao* include dispelling wind and dampness, relaxing muscles and tendons, reducing swelling, removing dampness and detoxifying.

[0091] Herbs that can dispel wind and dampness, relax muscles and promote blood circulation, detoxify and relieve pain, and disperse blood stasis and reduce swelling;

[0092] Scutellaria baicalensis clears heat and dries dampness, purges fire and detoxifies;

[0093] Phellodendron bark is bitter and cold in nature, and enters the kidney and bladder meridians. It has the effects of clearing heat and drying dampness, purging fire and eliminating steaming, and detoxifying and healing sores.

[0094] Sophora flavescens is the dried root of Sophora flavescens, a legume. It is bitter and cold in nature, and enters the heart, liver, stomach, large intestine, and bladder meridians. It has the effects of clearing heat and drying dampness, and promoting diuresis.

[0095] Dipsacus asperoides has the effects of tonifying the liver and kidneys, strengthening tendons and bones, healing fractures, and regulating blood circulation.

[0096] Cuscuta chinensis has the effects of tonifying the liver and kidneys, consolidating essence and reducing urination, and improving eyesight;

[0097] Abalone shell has the effects of calming the liver and suppressing yang, clearing the liver and improving eyesight;

[0098] Alisma has the effects of promoting diuresis and eliminating dampness, clearing heat, resolving turbidity and lowering lipids;

[0099] Green mulberry leaves have the effects of dispersing wind-heat, clearing the lungs and moisturizing dryness, and clearing the liver and improving eyesight;

[0100] Privet fruit has the effects of nourishing the liver and kidneys, darkening hair, and improving eyesight;

[0101] Psoralea corylifolia has the effects of tonifying the kidneys and strengthening yang, consolidating essence and reducing urination, and warming the spleen and stopping diarrhea.

[0102] Epimedium has the effects of tonifying the kidneys and strengthening yang, dispelling wind and dampness, and strengthening muscles and bones;

[0103] Plantain seed has the effects of clearing heat and promoting diuresis, relieving strangury, eliminating dampness and stopping diarrhea, improving eyesight, and eliminating phlegm;

[0104] Dried ginger has the effects of warming the middle jiao and dispelling cold, restoring yang and unblocking the meridians, and warming the lungs and resolving phlegm.

[0105] Rhubarb has the effects of purging accumulations, clearing heat and purging fire, cooling blood and detoxifying, removing blood stasis and promoting menstruation, and promoting diuresis and relieving jaundice;

[0106] Fresh ginger can induce sweating to relieve exterior syndromes, warm the middle jiao to stop vomiting, warm the lungs to stop coughing, and detoxify.

[0107] The main effects of jujubes are to replenish qi and blood, and to calm the mind. They are generally good for strengthening the spleen.

[0108] Elm seeds, the fruit of the elm tree, are not only a traditional food ingredient, but also have a variety of health benefits, including strengthening the spleen and stomach, calming the nerves and aiding sleep, reducing swelling, relieving cough and phlegm, clearing lung heat, and lowering lung qi.

[0109] The effects and benefits of mulberries include: antioxidant properties, enhanced immunity, improved vision, nourishing yin and blood, lowering blood lipids, and lowering blood sugar.

[0110] Raspberries are sweet, sour, and slightly warm in nature. They enter the liver and kidney meridians and have the effects of tonifying kidney yang, astringing essence, and reducing urination. Raspberries are sweet and nourishing, sour and astringent. They are warm in nature but not hot. They can tonify kidney yang without harming kidney yin, and consolidate without causing stagnation. They can tonify and consolidate, and have the effect of sealing and storing. They are good at treating symptoms of kidney deficiency and instability.

[0111] The preparation method of a prescription for vegetative state patients includes the following steps:

[0112] Step 1: Raw Material Pretreatment: Prepare the following ingredients: Angelica sinensis, Trichosanthes kirilowii, Achyranthes bidentata, Achyranthes bidentata, Pheretima aspergillum, Eupolyphaga sinensis, raw oyster shell, raw dragon bone, Scrophularia ningpoensis, Bombyx batryticatus, Saposhnikovia divaricata, Hematite, Sophora japonica leaves, Salvia miltiorrhiza, Ligusticum chuanxiong, Asarum heterotropoides, Rehmannia glutinosa (raw and processed), chicken gizzard lining, Glauber's salt, malt, Artemisia capillaris, Melia toosendan, Euryale ferox, Asparagus cochinchinensis, Nardostachys chinensis, Coptis chinensis, Strychnos nux-vomica (processed), Cornus officinalis, Anemarrhena asphodeloides, Platycladus orientalis, Clematis chinensis, Crataegus pinnatifida peel, Panax notoginseng, Paeonia lactiflora, Paeonia veitchii, Paeonia suffruticosa, walnut kernel, raw licorice root, Acorus tatarinowii, Tetrapanax papyriferus, Akebia trifoliata, Schisandra chinensis, raw magnetite, Cynanchum paniculatum, borax, fresh Portulaca oleracea, Gastrodia elata, Notopterygium incisum. Polygala tenuifolia, Angelica pubescens, Gypsum fibrosum, Lycium barbarum, Lycopodium clavatum, Clematis chinensis, Scutellaria baicalensis, Phellodendron chinense, Convolvulus arvense, Sophora flavescens, Dipsacus asper, Cuscuta chinensis, Codonopsis pilosula, Atractylodes macrocephala (fried), Dioscorea opposita, Haliotis diversicolor, Alisma plantago-aquatica, Morus alba leaves, Ligustrum lucidum, dried radish slices, Psoralea corylifolia, Epimedium brevicornu, Plantago asiatica, and optional ingredients such as dried ginger, rhubarb, fresh ginger, jujube, Elm seeds, mulberry, and Rubus idaeus are selected, washed, and dried. Fresh ingredients such as fresh purslane, fresh yam, fresh ginger, and fresh Convolvulus arvense need to be vacuum dried at low temperature until the moisture content is ≤8% to maintain the stability of active ingredients.

[0113] Step 2: Raw Material Classification and Pulverization: The dried raw materials are classified into three categories according to their medicinal properties: mineral raw materials, animal raw materials, and plant raw materials. Mineral raw materials include raw oyster shell, raw dragon bone, hematite, borax, raw magnetite, raw gypsum, and abalone shell. Animal raw materials include earthworm, ground beetle, chicken gizzard lining, processed strychnine, gastrodia, and silkworm. Plant raw materials include angelica, trichosanthes root, achyranthes root, Sichuan achyranthes root, scrophularia root, saposhnikovia root, locust leaf, salvia root, chuanxiong rhizome, asarum, raw rehmannia root, prepared rehmannia root, mirabilite, malt, artemisia capillaris, Sichuan chinaberry, euryale seed, asparagus root, nardostachys root, coptis root, and cornus fruit. Anemarrhena asphodeloides, raw arborvitae seed, Clematis chinensis, raw hawthorn peel, Panax notoginseng, white peony root, red peony root, peony bark, walnut kernel, raw licorice root, Acorus tatarinowii, Tetrapanax papyriferus, Akebia quinata, Schisandra chinensis, Cynanchum paniculatum, dried fresh purslane, Notopterygium incisum, Polygala tenuifolia, Angelica pubescens, Lycium barbarum, Lycopodium clavatum, Clematis armandii, Scutellaria baicalensis, Phellodendron chinense, dried Convolvulus arvense, Sophora flavescens, Dipsacus asper, Cuscuta chinensis, Codonopsis pilosula, stir-fried Atractylodes macrocephala, dried fresh Dioscorea opposita, Alisma plantago-aquatica, Morus alba leaf, Ligustrum lucidum, dried radish slices, Psoralea corylifolia, Epimedium brevicornu, Plantago asiatica, and optional additions such as dried ginger, rhubarb, dried fresh ginger, jujube, Elm seed, mulberry, and raspberry.

[0114] Step 3, Raw Material Grinding: Select grinding methods according to the characteristics of different types of raw materials. Among them, mineral raw materials are ground by air jet milling to a particle size ≤10μm to form ultrafine mineral powder; animal raw materials are ground by low temperature freeze grinding to a particle size ≤15μm to prevent high temperature from destroying their bioactive components; plant raw materials are processed by ultra-micro grinding technology to a particle size ≤20μm to improve the dissolution efficiency of effective components in subsequent extraction processes.

[0115] Step 4, Dynamic Extraction: Mix the three types of raw materials after crushing evenly according to the prescription ratio, and put them into the dynamic extraction equipment. Set the extraction temperature of the dynamic extraction equipment to 65-75℃, add 8-12 times the amount of purified water as the extraction solvent, and perform the first extraction for 90 minutes. After filtering and collecting the first extract, add 6-8 times the amount of purified water to the residue again, and repeat the above extraction operation twice, with each extraction taking 60 minutes. Combine the three extracts for later use.

[0116] Step 5, solid-liquid separation: The combined extract is filtered through a plate and frame filter press to remove the filter residue. The filtrate is then finely filtered through a microporous membrane to obtain the separated solid and liquid drug solutions.

[0117] Step 6, Concentration: The filtered liquid is concentrated using a vacuum concentration device. The vacuum degree of the vacuum concentration device is 0.08-0.09MPa and the temperature is 55℃±5℃. The relative density of the concentrated liquid is 1.25-1.30, and it is concentrated into a thick paste.

[0118] Step 7, Granulation preparation: Mix the concentrated paste and dextrin (the mass ratio of concentrated paste to dextrin is 1:0.8) evenly to form a soft material, granulate it using the first sieve (18 mesh sieve), place the wet granules in a low-temperature drying oven to dry to a moisture content ≤5% (the temperature of the low-temperature drying oven is 45℃), and then granulate them by passing them through the second sieve (20 mesh sieve) to obtain uniform intermediate granules;

[0119] Step 8, Post-processing: The intermediate particles are ultra-finely pulverized to a particle size ≤10μm to prepare the target powder. The powder is then sterilized by irradiation (dose 5-10kGy) to ensure that the microbial limits meet the requirements.

[0120] Step 9, Packaging: Finally, package the product into aluminum-plastic composite bags or pharmaceutical glass bottles in 5g per bag or 100g per bottle, seal the packaging, and affix labels containing information such as product name, ingredients, specifications, production date, and shelf life. Store the product in a cool, dry place.

[0121] The above methods and steps can fully preserve the active ingredients and medicinal value of various raw materials in the prescription, and prepare a vegetative state prescription powder with uniform particle size, high purity, and microbial limits. This preparation is not only easy for patients to take and absorb, but also ensures the safety and effectiveness of clinical application through strict quality control, providing a stable and reliable material basis for the rehabilitation and adjuvant treatment of vegetative state patients.

[0122] A method of using a prescription for vegetative state patients, comprising any of the above-mentioned prescriptions for vegetative state patients, decocted in water and taken orally, one dose per day, once in the morning and once in the evening.

[0123] Test case

[0124] 1. Ms. Cao, 67 years old, a resident of Daocheng Community, Songling Subdistrict. She suddenly fainted on July 31, 2023. After three days of unsuccessful rescue efforts at the hospital, she fell into a coma and was in a vegetative state. After diagnosis and one day of medication, the patient successfully regained consciousness. She continued to receive medication and was discharged the following day.

[0125] 2. Niu Moumou, male, resident of Zichuan District. In July 2023, he developed symptoms of dizziness, nausea, and weakness in his limbs. After falling into a coma, he was hospitalized for a month and gradually developed into a vegetative state. After diagnosis and treatment, a vegetative state prescription was applied. The patient regained consciousness three days later and was discharged a week later.

[0126] 3. Ms. Wu, 69 years old. She was hospitalized in 2020 due to cerebral infarction and subsequently lost consciousness and was in a vegetative state. After a week of continuous medication, her consciousness was restored, and she was discharged from the hospital two weeks later in good health.

[0127] It should be noted that, in this document, relational terms such as "first" and "second" are used only to distinguish one entity or operation from another, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Furthermore, the terms "comprising," "including," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such process, method, article, or apparatus.

[0128] Although embodiments of the invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A prescription for vegetative state patients, characterized in that, The following raw materials are included by weight: Angelica sinensis 50g, Trichosanthes kirilowii 50g, Achyranthes bidentata 290g, Achyranthes bidentata 70g, Pheretima aspergillum 200g, Eupolyphaga sinensis 100g, Ostrea gigas 200g, Os draconis 100g, Scrophularia ningpoensis 100g, Bombyx mori 20g, Saposhnikovia divaricata 60g, Hematite 200g, Sophora japonica leaves 200g, Salvia miltiorrhiza 240g, Ligusticum chuanxiong 50g, Asarum sieboldii 20g, Rehmannia glutinosa 100g, Rehmannia glutinosa (processed) 200g Chicken gizzard lining 120g, Glauber's salt 100g, malt 30g, Artemisia capillaris 30g, Sichuan pepper 50g, Euryale ferox 100g, Asparagus cochinchinensis 80g, Nardostachys chinensis 50g, Coptis chinensis 10g, processed Strychnos nux-vomica 0.33g, Cornus officinalis 100g, Anemarrhena asphodeloides 100g, raw Platycladus orientalis 45g, Clematis chinensis 20g, raw Crataegus pinnatifida peel 300g, Panax notoginseng 300g, white peony root 10g, red peony root 100g 80g of Moutan bark, 150g of walnut kernels, 50g of raw licorice root, 30g of Acorus tatarinowii rhizome, 30g of Tetrapanax papyriferus pith, 30g of Akebia quinata root, 40g of Schisandra chinensis fruit, 120g of raw magnetite, 100g of Cynanchum paniculatum root, 30g of borax, 100g of fresh purslane, 200g of Gastrodia elata rhizome, 20g of Notopterygium incisum root, 50g of Polygala tenuifolia root, 20g of Angelica pubescens root, 120g of raw gypsum, 180g of wolfberry fruit, and 120g of Lycopodium clavatum root. 100g of Clematis armandii, 100g of Scutellaria baicalensis, 100g of Phellodendron chinense, 80g of Convolvulus arvense, 30g of Sophora flavescens, 50g of Dipsacus asper, 160g of Cuscuta chinensis, 50g of Codonopsis pilosula, 80g of Atractylodes macrocephala (fried), 150g of Dioscorea opposita (fresh), 200g of Haliotis diversicolor, 40g of Alisma plantago-aquatica, 50g of Morus alba (green mulberry leaf), 60g of Ligustrum lucidum (nu zi), 200g of dried radish slices, 50g of Psoralea corylifolia, 50g of Epimedium brevicornu, and 60g of Plantago asiatica.

2. The prescription for vegetative state patients according to claim 1, characterized in that, Also includes: Seven slices of dried ginger, rhubarb, and fresh ginger.

3. The prescription for vegetative state patients according to claim 1, characterized in that, The rhubarb is ground into powder to make rhubarb powder.

4. The prescription for vegetative state patients according to claim 1, characterized in that, Also includes: Ten jujubes, ten elm seeds, ten mulberries, and ten purple raspberries.

5. The prescription for vegetative state patients according to claim 1, characterized in that, The amount of Convolvulus is prepared by mixing fresh Convolvulus and Convolvulus paste in a 3:1 ratio, with 60g of fresh Convolvulus and 20g of Convolvulus paste.

6. The prescription for vegetative state patients according to any one of claims 1-5, characterized in that, The method for preparing the vegetative state prescription includes the following steps: Step 1: Raw material pretreatment: Prepare the following ingredients: Angelica sinensis, Trichosanthes kirilowii, Achyranthes bidentata, Achyranthes bidentata, Pheretima aspergillum, Eupolyphaga sinensis, raw oyster shell, raw dragon bone, Scrophularia ningpoensis, Bombyx batryticatus, Saposhnikovia divaricata, Hematite, Sophora japonica leaves, Salvia miltiorrhiza, Ligusticum chuanxiong, Asarum heterotropoides, Rehmannia glutinosa (raw and processed), chicken gizzard lining, Glauber's salt, malt, Artemisia capillaris, Melia toosendan, Euryale ferox, Asparagus cochinchinensis, Nardostachys chinensis, Coptis chinensis, Strychnos nux-vomica (processed), Cornus officinalis, Anemarrhena asphodeloides, Platycladus orientalis, Clematis chinensis, Crataegus pinnatifida peel, Panax notoginseng, Paeonia lactiflora, Paeonia suffruticosa, Paeonia suffruticosa, walnut kernel, raw licorice root, Acorus tatarinowii, Tetrapanax papyriferus, Akebia trifoliata, Schisandra chinensis, raw magnetite, Cynanchum paniculatum, borax, fresh Portulaca oleracea, Gastrodia elata, and Notopterygium incisum. The following ingredients are selected, washed, and dried: Polygala tenuifolia, Angelica pubescens, Gypsum fibrosum, Lycium barbarum, Lycopodium clavatum, Clematis chinensis, Scutellaria baicalensis, Phellodendron chinense, Convolvulus arvense, Sophora flavescens, Dipsacus asper, Cuscuta chinensis, Codonopsis pilosula, Atractylodes macrocephala (fried), Dioscorea opposita, Haliotis diversicolor, Alisma plantago-aquatica, Morus alba leaves, Ligustrum lucidum, dried radish slices, Psoralea corylifolia, Epimedium brevicornu, Plantago asiatica, and optional ingredients such as dried ginger, rhubarb, fresh ginger, jujube, Elm seeds, mulberry, and Rubus idaeus. Fresh ingredients such as fresh purslane, fresh yam, fresh ginger, and fresh Convolvulus arvense need to be vacuum dried at low temperature until the moisture content is ≤8% to maintain the stability of the active ingredients. Step 2: Raw Material Classification and Pulverization: The dried raw materials are classified into three categories according to their medicinal properties: mineral raw materials, animal raw materials, and plant raw materials. The mineral raw materials include raw oyster shell, raw dragon bone, red ochre, borax, raw magnetite, raw gypsum, and abalone shell. The animal raw materials include earthworm, ground beetle, chicken gizzard lining, processed strychnine, gastrodia, and silkworm. The plant raw materials include angelica, trichosanthes root, achyranthes root, Sichuan achyranthes root, scrophularia root, saposhnikovia root, locust leaf, salvia root, chuanxiong rhizome, asarum, raw rehmannia root, prepared rehmannia root, mirabilite, malt, artemisia capillaris, Sichuan chinaberry, euryale seed, asparagus root, nardostachys root, coptis root, and yam. Cornus officinalis, Anemarrhena asphodeloides, Platycladus orientalis seeds, Clematis chinensis, Crataegus pinnatifida peel, Panax notoginseng, Paeonia lactiflora, Paeonia veitchii, Paeonia suffruticosa, walnut kernels, Glycyrrhiza uralensis, Acorus tatarinowii, Tetrapanax papyriferus, Akebia trifoliata, Schisandra chinensis, Cynanchum paniculatum, dried fresh Portulaca oleracea, Notopterygium incisum, Polygala tenuifolia, Angelica pubescens, Lycium barbarum, Lycopodium clavatum, Clematis armandii, Scutellaria baicalensis, Phellodendron chinense, dried Convolvulus arvense, Sophora flavescens, Dipsacus asper, Cuscuta chinensis, Codonopsis pilosula, stir-fried Atractylodes macrocephala, dried fresh Dioscorea opposita, Alisma plantago-aquatica, Morus alba leaves, Ligustrum lucidum, dried radish slices, Psoralea corylifolia, Epimedium brevicornu, Plantago asiatica, and optional additions such as dried ginger, rhubarb, dried fresh ginger, jujube, Elm seeds, mulberry, and raspberry. Step 3, Raw Material Crushing: Select the crushing method according to the characteristics of different types of raw materials. Among them, the mineral raw materials are crushed by air jet milling to a particle size ≤10μm to form ultrafine mineral powder; the animal raw materials are crushed by cryogenic freezing to a particle size ≤15μm; and the plant raw materials are processed by ultrafine crushing technology to a particle size ≤20μm. Step 4, Dynamic Extraction: Mix the three types of raw materials after crushing evenly according to the prescription ratio, put them into the dynamic extraction equipment, add 8-12 times the amount of purified water as the extraction solvent, and perform the first extraction; after filtering and collecting the first extract, add 6-8 times the amount of purified water to the residue again, and repeat the above extraction operation twice; combine the three extracts for later use. Step 5, solid-liquid separation: The combined extract is filtered through a plate and frame filter press to remove the filter residue. The filtrate is then finely filtered through a microporous membrane to obtain the separated solid and liquid drug solutions. Step 6, Concentration: The filtered liquid is concentrated into a thick paste using a vacuum concentration device; Step 7, Granulation preparation: Mix the concentrated paste with dextrin evenly to form a soft material, granulate it with the first sieve, place the wet granules in a low temperature drying oven to dry until the moisture content is ≤5%, and then granulate them through the second sieve to obtain uniform intermediate granules. Step 8, Post-processing: The intermediate particles are ultra-finely pulverized to a particle size ≤10μm to prepare the target powder, and the powder is sterilized by irradiation. Step 9, Packaging: Finally, package the product into aluminum-plastic composite bags or pharmaceutical glass bottles in 5g per bag or 100g per bottle, seal the packaging, and affix labels containing information such as product name, ingredients, specifications, production date, and shelf life. Store the product in a cool, dry place.

7. The prescription for vegetative state patients according to claim 6, characterized in that, The dynamic extraction device is set to an extraction temperature of 65-75℃, with the first extraction time being 90 minutes and the subsequent two extraction times being 60 minutes.

8. The prescription for vegetative state patients according to claim 6, characterized in that, The vacuum degree of the vacuum concentration device is 0.08-0.09 MPa, the temperature is 55℃±5℃, and the relative density of the concentrated product is 1.25-1.

30.

9. The prescription for vegetative state patients according to claim 6, characterized in that, The mass ratio of the concentrated paste to dextrin is 1:0.

8. The first sieve is an 18-mesh sieve, the temperature of the low-temperature drying oven is 45℃, and the second sieve is a 20-mesh sieve.

10. A method of using a vegetative state prescription, comprising the vegetative state prescription according to any one of claims 1-9, characterized in that, Decoct in water and take one dose daily, once in the morning and once in the evening.