Nutrient capable of invigorating spleen and tonifying kidney and preparation method thereof

Abstract

The nourishment is prepared from the following raw materials: gordon euryale seed, semen cuscutae, raspberry, fructus lycii, glossy privet fruit, achyranthes root, radix scrophulariae, rehmannia root, radix ophiopogonis, schisandra chinensis, rhizoma polygonati and rhodiola rosea through the process steps of extraction, drying, crushing, granulation, total mixing, filling, polishing, screening, packaging, radiation sterilization and the like. The nourishment with a good effect is produced. Compared with the prior art, the nutritional product has the following advantages that by effectively extracting the effective components of the medicines, the effects of replenishing qi and enriching blood, enriching yin and nourishing kidney, tonifying spleen and nourishing stomach and regulating qi and blood weakness and viscera dysfunction of a human body are achieved, so that the effects of enhancing immunity and relieving physical fatigue are achieved.

Description

Technical Field

[0001] This application relates to the field of drug extraction technology, and in particular to a nutritional product for strengthening the spleen and kidneys and its preparation method. Background Technology

[0002] With the fast pace of modern life and changes in dietary structure, spleen and kidney deficiency has become a common health problem. The spleen governs digestion and absorption, while the kidneys are the foundation of innate essence. Dysfunction of the spleen and kidneys can lead to various symptoms such as indigestion, fatigue, weakness in the lower back and knees, and weakened immunity. Therefore, developing safe and effective nutritional products that strengthen the spleen and kidneys is of significant practical importance.

[0003] However, existing spleen-strengthening and kidney-tonifying products still have the following shortcomings: First, the raw material ratios of existing products often lack scientific basis, and the synergistic effect between various components is not fully utilized, resulting in an unsatisfactory overall efficacy in strengthening the spleen and kidneys; second, some products have simple processing methods, making it difficult to fully release the active ingredients in the ingredients, resulting in low absorption efficiency by the human body; third, some compound nutritional products add excessive food additives to improve taste and extend shelf life, affecting the naturalness and safety of the products; finally, existing products often suffer from serious nutrient loss during the preparation process, failing to meet consumers' demand for natural, efficient, and safe spleen-strengthening and kidney-tonifying health products.

[0004] Traditional Chinese medicine believes that enhancing immunity primarily achieves therapeutic effects through the principle of "strengthening the body's resistance and eliminating pathogenic factors." The saying goes, "When the body's vital energy is abundant, pathogenic factors cannot invade." Therefore, as long as the body's vital energy is strong, its immunity can be improved. Fatigue is related to weakness of qi and blood, and dysfunction of the internal organs. By finding ways to improve the body's vital energy and balance the functions of the internal organs, physical fatigue can be alleviated.

[0005] Based on existing technical features, this invention provides a nutritional product for strengthening the spleen and kidneys and its preparation method. The formula specifically selects traditional Chinese medicines that invigorate qi and blood, nourish yin and kidneys, and strengthen the spleen and stomach to regulate the deficiency of qi and blood and the dysfunction of internal organs, thereby achieving the effects of enhancing immunity and relieving physical fatigue. Summary of the Invention

[0006] The purpose of this invention is to overcome the shortcomings of the prior art and provide a nutritional product for strengthening the spleen and kidneys and its preparation method.

[0007] This invention is achieved through the following technical solution: a method for preparing a nutritional product that strengthens the spleen and kidneys, characterized by comprising the following steps: Step 1: Prepare the medicine. Weigh out the following ingredients according to the formula: Cuscuta chinensis, Lycium barbarum, Achyranthes bidentata, Scrophularia ningpoensis, Rehmannia glutinosa, and Polygonatum sibiricum to prepare the first prescription. Weigh out the following ingredients according to the formula: Euryale ferox, Rubus idaeus, Ligustrum lucidum, Ophiopogon japonicus, and Schisandra chinensis to prepare the second prescription. Step 2, Extraction 1: Place the first prescription in an extraction tank, add water to soak for 2 hours, heat and decoct. After decoction for 1 hour, add Rhodiola rosea and continue heating for 1 hour. Filter, add water to the residue and decoct for another 1.5 hours, then filter. Combine the filtrates from the two filtrations, let stand for 24 hours, then take the supernatant and filter. The filtrate is Solution 1. Step 3, Extraction 2: Place Formula 2 in an extraction tank, add water to soak for 2 hours, heat and decoct for 2 hours, then filter. Add water to the residue and decoct for another 1.5 hours, then filter. Combine the filtrates from the two filtrations, let stand for 24 hours, then take the supernatant and filter. The filtrate is Solution 2. Step 4: Concentration. The solution obtained in Step 3 is concentrated to a fluid extract with a relative density of 1.10 to 1.15. The temperature of the fluid extract is 80°C. Step 5: Alcohol precipitation. Place the fluid extract prepared in Step 4 into an alcohol precipitation tank, cool to room temperature, add ethanol until the alcohol content is 60% by mass, stir evenly, let stand for 24 hours, take the supernatant and filter it through a 200-mesh sieve, recover the ethanol from the filtrate, and obtain solution 3. Step 6: Concentration and drying. Mix solution 1 obtained in step 2 with solution 3 obtained in step 5, and concentrate to an extract with a relative density of 1.20 to 1.25. Dry the extract under reduced pressure at 80°C, 65 to 75°C, and 0.06 to 0.08 MPa to obtain a dry extract. Step 7: Grind and sieve. Grind the dry extract obtained in Step 6 and pass it through an 80-mesh sieve to obtain the medicinal powder. Step 8: Granulation. Place the powder obtained in step 7 into a trough mixer, add 90% to 95% (by volume) of ethanol aqueous solution and stir evenly. Granulate using an 18-mesh stainless steel sieve, dry at 65°C to 85°C, and granulate using a 20-mesh stainless steel sieve. Add 0.5% (by total mass) of magnesium stearate to the mixture. As a further improvement to the above scheme, in step one, the content of Cuscuta chinensis, Lycium barbarum, Achyranthes bidentata, Scrophularia ningpoensis, Rehmannia glutinosa, and Polygonatum sibiricum in prescription one is as follows: Cuscuta chinensis 6-15 parts, Lycium barbarum 3-10 parts, Achyranthes bidentata 3-10 parts, Scrophularia ningpoensis 5-15 parts, Rehmannia glutinosa 5-15 parts, and Polygonatum sibiricum 3-20 parts.

[0008] The content of Euryale ferox, Rubus idaeus, Ligustrum lucidum, Ophiopogon japonicus, and Schisandra chinensis in prescription two is as follows: Euryale ferox 6-20 parts, raspberry 3-10 parts, privet fruit 5-20 parts, dandelion 5-15 parts, ophiopogon japonicus 3-10 parts, schisandra chinensis 3-10 parts In step two, the amount of Rhodiola rosea added is 3 to 6 parts.

[0009] As a further improvement to the above scheme, in step one, the content of Cuscuta chinensis, Lycium barbarum, Achyranthes bidentata, Scrophularia ningpoensis, Rehmannia glutinosa, and Polygonatum sibiricum in prescription one is as follows: Cuscuta chinensis 13 parts, Lycium barbarum 5 parts, Achyranthes bidentata 6 parts, Scrophularia ningpoensis 10 parts, Rehmannia glutinosa 10 parts, and Polygonatum sibiricum 6.5 parts. Prescription 2 contains the following amounts of Euryale ferox, Rubus idaeus, Ligustrum lucidum, Ophiopogon japonicus, and Schisandra chinensis: Euryale ferox 12 parts, Rubus idaeus 6 parts, Ligustrum lucidum 10 parts, Ophiopogon japonicus 6.5 parts, and Schisandra chinensis 6.5 parts. In step two, the amount of Rhodiola rosea added is 5 parts.

[0010] As a further improvement to the above scheme, in step two, the mass of the water used for soaking is 8 to 10 times the total mass of the medicinal materials in prescription one, and the mass of the water used for decocting the residue is 8 times the total mass of the medicinal materials in prescription one; in step three, the mass of the water used for soaking is 8 to 10 times the total mass of the medicinal materials in prescription two, and the mass of the water used for decocting the residue is 8 times the total mass of the medicinal materials in prescription two.

[0011] As a further improvement to the above scheme, steps seven to nine are operated under a Class 100,000 cleanroom environment.

[0012] Compared with the prior art, the present invention has the following advantages: This health capsule effectively extracts the effective components of the above-mentioned drugs to achieve the effects of invigorating qi and nourishing blood, nourishing yin and tonifying the kidneys, strengthening the spleen and nourishing the stomach, regulating the deficiency of qi and blood and the dysfunction of the internal organs, thereby enhancing immunity and relieving physical fatigue. Detailed Implementation

[0013] The technical solutions in the embodiments of this application will be clearly and completely described below with reference to the embodiments of this application. Obviously, the described embodiments are some, but not all, of the embodiments of this invention. Based on the embodiments of this invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of this invention.

[0014] A nutritional product for strengthening the spleen and kidneys and its preparation method, comprising the following steps: Step 1: Prepare the medicine. Weigh out the following ingredients according to the prescription: Cuscuta chinensis, Lycium barbarum, Achyranthes bidentata, Scrophularia ningpoensis, Rehmannia glutinosa, and Polygonatum sibiricum. Prepare the following formula: The content of Cuscuta chinensis, Lycium barbarum, Achyranthes bidentata, Scrophularia ningpoensis, Rehmannia glutinosa, and Polygonatum sibiricum is as follows: Cuscuta chinensis 13 parts, Lycium barbarum 5 parts, Achyranthes bidentata 6 parts, Scrophularia ningpoensis 10 parts, Rehmannia glutinosa 10 parts, Polygonatum sibiricum 6.5 parts; Next, according to the formula, weigh out the following ingredients: foxnut, raspberry, privet fruit, ophiopogon root, and schisandra fruit to prepare formula two. The content of these ingredients is as follows: 12 parts of Euryale ferox, 6 parts of Rubus idaeus, 10 parts of Ligustrum lucidum, 6.5 parts of Ophiopogon japonicus, and 6.5 parts of Schisandra chinensis; Step Two, Extraction One: Place Formula One in an extraction tank, add water to soak for 2 hours, then heat and decoct. The mass of the water used for soaking should be 8 times the total mass of the medicinal materials in Formula One. After decoction for 1 hour, add 2 parts of Rhodiola rosea, continue heating for 1 hour, filter, add water to the residue and decoct again for 1.5 hours, then filter again. The mass of the water used for decoction again should be 8 times the total mass of the medicinal materials in Formula One. Combine the filtrates from the two filtrations, let stand for 24 hours, then filter the supernatant. The filtrate is Solution One. In addition to containing rhodioloside and various flavonoids, Rhodiola rosea is also rich in various amino acids, vitamins, and essential trace elements. Therefore, in order to ensure the full extraction of effective components and reduce the damage to trace elements during decoction, it is added later in the decoction process to reduce the high-temperature decoction time.

[0015] Step 3, Extraction 2: Place Formula 2 in an extraction tank, add water and soak for 2 hours. The mass of the water used for soaking should be 8 times the total mass of the medicinal materials in Formula 2. Heat and decoct for 2 hours, then filter. Add water to the residue and decoct for another 1.5 hours. Add water to the residue and decoct for another 1.5 hours. The mass of the water used for decoction should be 8 times the total mass of the medicinal materials in Formula 2. Filter, combine the filtrates from the two filtrations, let stand for 24 hours, then take the supernatant and filter. The filtrate is Solution 2. Step 4: Concentration. The solution obtained in Step 3 is concentrated to a fluid extract with a relative density of 1.10 to 1.15. The temperature of the fluid extract is 80°C. This step allows some of the solvent to evaporate, reducing the amount of ethanol consumed during alcohol precipitation. At the same time, the preliminary concentration also allows some poorly water-soluble inactive components to be precipitated and removed.

[0016] Step 5: Alcohol precipitation. Place the fluid extract obtained in Step 4 into an alcohol precipitation tank, cool to room temperature, add ethanol until the alcohol content reaches 60% by mass, stir evenly, and let stand for 24 hours. Take the supernatant and filter it through a 200-mesh sieve. Recover the ethanol from the filtrate to obtain Solution 3. The purpose of alcohol precipitation is to remove impurities and purify the solution. The principle of this method is based on the characteristic that the effective components of the drug in this invention, such as glycosides, organic acid salts, amino acids, and polysaccharides, are easily soluble in water and alcohol. Water is used for extraction, and the extract is concentrated. Appropriate ethanol is added, and after one or more precipitation cycles, insoluble substances are precipitated, finally yielding a clear liquid. The use of a 60% alcohol concentration employs a selective dissolution method for the effective components of the medicinal material, meaning that all effective components can be dissolved, and the alcohol-soluble content no longer increases with increasing alcohol concentration, while the alcohol-insoluble substances in the water extract are precipitated and removed.

[0017] Step Six: Concentration and Drying. Mix Solution One obtained in Step Two with Solution Three obtained in Step Five, and concentrate to an extract with a relative density of 1.20–1.25. Dry the extract at 80°C, 65–75°C, and 0.06–0.08 MPa under reduced pressure to obtain a dry extract. The extract at this concentration has a low water content, which is beneficial for the next step of reduced pressure drying and prevents the extract from gelatinizing and losing the active ingredients.

[0018] Step 7: Crush and sieve. Under 100,000-level purification conditions, crush the dry extract obtained in step 6 and pass it through an 80-mesh sieve to obtain the medicinal powder. Step 8: Granulation. Under 100,000-level cleanroom conditions, place the powder obtained in Step 7 into a trough mixer, add 90% to 95% (by volume) of ethanol aqueous solution and stir evenly. Granulate using an 18-mesh stainless steel sieve, dry at 65°C to 85°C, and granulate using a 20-mesh stainless steel sieve. Add 0.5% (by total mass) of magnesium stearate to the mixture. Polygonatum is sweet and neutral in nature, and enters the spleen, lung, and kidney meridians. It has the functions of replenishing qi and nourishing yin, strengthening the spleen, moistening the lungs, and benefiting the kidneys. It is used for yin deficiency cough, dry cough, spleen deficiency and fatigue, poor appetite and dry mouth, diabetes, kidney deficiency and soreness of the waist and knees, impotence and seminal emission, tinnitus and blurred vision, premature graying of hair, physical weakness and emaciation, and tinea. It is a product for replenishing yin.

[0019] Scrophularia is sweet, bitter, and salty, and enters the lung, stomach, and kidney meridians. It has the effects of cooling blood and nourishing yin, purging fire and detoxifying, and is used to treat yin deficiency caused by febrile diseases, red tongue with thirst, fever with rashes, constipation due to fluid depletion, steaming cough due to bone heat, red eyes, sore throat, scrofula, diphtheria, carbuncles and boils.

[0020] Schisandra chinensis has the effects of astringing the lungs and promoting the production of body fluids, tonifying the kidneys and nourishing the heart, and consolidating and astringing. It is used for lung deficiency cough, thirst due to fluid depletion, spontaneous sweating and night sweats, nocturnal emission and spermatorrhea, chronic diarrhea and dysentery, insomnia and forgetfulness, and palpitations.

[0021] Cuscuta seed is sweet, neutral, and non-toxic. It has the effects of tonifying the kidney and replenishing essence, nourishing the liver and improving eyesight. It is used for symptoms such as soreness and weakness of the waist, knees and bones, impotence, seminal emission, delirium, frequent urination, dribbling after urination, dizziness, blurred vision, tinnitus and deafness, as well as leukorrhea and habitual miscarriage in women due to deficiency of liver and kidney.

[0022] Sweet and neutral in nature, it enters the spleen, lung, and kidney meridians. Its functions include tonifying the spleen and stomach, promoting body fluid production and benefiting the lungs, and tonifying the kidneys and astringing essence. It has the effects of strengthening the spleen and stomach, benefiting the lungs and kidneys, and replenishing deficiency and weakness. It is used for spleen deficiency with poor appetite, diarrhea and loose stools, lung deficiency with cough and asthma, kidney deficiency with seminal emission, excessive leukorrhea, frequent urination, and thirst due to deficiency heat.

[0023] Euryale ferox is sweet, astringent, and neutral in nature, entering the spleen and kidney meridians. Its main functions are to tonify the spleen and stop diarrhea, and to strengthen the kidneys and astringe semen. Because of its sweet taste, it can tonify the spleen; because of its astringent taste, it can strengthen the kidneys, thus it can control qi and cure seminal emission and urinary incontinence.

[0024] Privet fruit is sweet, bitter, and neutral in nature. It enters the liver and kidney meridians. It has the functions of tonifying the liver and kidneys, nourishing yin and blood, clearing deficiency heat, strengthening the waist and knees, improving eyesight and hearing, and darkening hair. It is used for liver and kidney yin deficiency, dizziness and tinnitus, soreness and weakness of the waist and knees, premature graying of hair, blurred vision, internal heat and thirst, and night sweats. Privet fruit contains ursolic acid, mannitol, glucose, and fatty oils, which have the effects of enhancing immunity, anti-fatigue, and anti-aging.

[0025] Ophiopogon japonicus is sweet, bitter, and cold in nature, and enters the heart, lung, and stomach meridians. It has the functions of nourishing yin and promoting body fluids, moistening the lungs, benefiting the stomach and promoting body fluids, and clearing the heart and relieving irritability. It is used for symptoms such as dry cough due to lung heat, consumptive cough due to yin deficiency, dry throat and sore throat, thirst due to fluid depletion, internal heat and thirst, hemoptysis, irritability and insomnia, and constipation due to intestinal dryness.

[0026] Achyranthes bidentata is bitter, sour, and neutral in nature, and enters the liver and kidney meridians. Its functions include promoting blood circulation and removing blood stasis, eliminating dampness and promoting diuresis, and clearing heat and detoxifying. It is mainly used to treat cold-dampness weakness and paralysis, limb contractures, knee pain with inability to flex or extend, to expel blood stasis, and to treat burns and ulcers. Long-term use can promote longevity and lighten the body. It is also used for gonorrhea, hematuria, amenorrhea, abdominal masses, rheumatic joint pain, beriberi, edema, dysentery, malaria, diphtheria, carbuncles, and traumatic injuries.

[0027] Goji berries are sweet and neutral in nature, and enter the liver and kidney meridians. They nourish the liver and kidneys, benefit essence and improve eyesight. They are used for deficiency of essence and blood, soreness of the waist and knees, dizziness and tinnitus, internal heat and thirst, blood deficiency and chlorosis, and blurred vision.

[0028] Rhodiola rosea is sweet, astringent, and cold in nature, and enters the lung and heart meridians. Its functions include clearing the lungs and relieving cough, stopping bleeding, and stopping leukorrhea. It also has the effects of invigorating qi and promoting blood circulation, unblocking the meridians and relieving asthma, clearing the lungs and relieving cough, and resolving blood stasis and reducing swelling. It is used for lung heat cough, hemoptysis, qi deficiency and blood stasis, chest pain, stroke hemiplegia, fatigue and shortness of breath. It can also improve sleep, promote blood production and circulation, resist cerebral hypoxia, combat fatigue, promote blood circulation and stop bleeding, reduce fever, and nourish vital energy.

[0029] Rehmannia glutinosa (raw) is sweet and cold in nature, and enters the heart, liver, and kidney meridians. Its functions include clearing heat and cooling the blood, nourishing yin and generating fluids. It also has the effects of dispelling blood stasis, replenishing bone marrow, and promoting muscle growth. It is used for febrile diseases with a crimson tongue, yin deficiency with internal heat, bone steaming fever, rashes, clearing accumulations of cold and heat, and relieving numbness.

[0030] Raspberries enter the liver, kidney, and bladder meridians, and have the effects of improving eyesight, tonifying yang, strengthening essence and nourishing the kidneys. They are used to nourish the liver and kidneys, reduce urination, improve eyesight, treat impotence and premature ejaculation, spermatorrhea, cold uterus and infertility, clear and thin leukorrhea, frequent urination and urinary incontinence, blurred vision, and premature graying of hair.

[0031] This nutritional supplement effectively extracts the active ingredients of the aforementioned drugs, achieving the effects of invigorating qi and blood, nourishing yin and kidneys, strengthening the spleen and stomach, regulating qi and blood deficiency and organ dysfunction, thereby enhancing immunity and relieving physical fatigue.

[0032] Example 2 A nutritional product for strengthening the spleen and kidneys and its preparation method, comprising the following steps: Step 1: Prepare the medicine. Weigh out the following ingredients according to the prescription: Cuscuta chinensis, Lycium barbarum, Achyranthes bidentata, Scrophularia ningpoensis, Rehmannia glutinosa, and Polygonatum sibiricum. Prepare the following prescription: Cuscuta chinensis 20 parts, Lycium barbarum 10 parts, Achyranthes bidentata 10 parts, and Scrophularia ningpoensis 15 parts. 15 parts Rehmannia glutinosa and 10 parts Polygonatum sibiricum; Next, according to the formula, weigh out the following ingredients: foxnut, raspberry, privet fruit, ophiopogon root, and schisandra fruit to prepare formula two. The content of these ingredients is as follows: 20 parts of Euryale ferox, 10 parts of Rubus idaeus, 15 parts of Ligustrum lucidum, 10 parts of Ophiopogon japonicus, and 10 parts of Schisandra chinensis.

[0033] Step Two, Extraction One: Place Formula One in an extraction tank, add water to soak for 2 hours, then heat and decoct. The mass of the water used for soaking should be 8 times the total mass of the medicinal materials in Formula One. After decoction for 1 hour, add 2 parts of Rhodiola rosea, continue heating for 1 hour, filter, add water to the residue and decoct again for 1.5 hours, then filter again. The mass of the water used for decoction again should be 8 times the total mass of the medicinal materials in Formula One. Combine the filtrates from the two filtrations, let stand for 24 hours, then filter the supernatant. The filtrate is Solution One. In addition to containing rhodioloside and various flavonoids, Rhodiola rosea is also rich in various amino acids, vitamins, and essential trace elements. Therefore, in order to ensure the full extraction of effective components and reduce the damage to trace elements during decoction, it is added later in the decoction process to reduce the high-temperature decoction time.

[0034] Step 3, Extraction 2: Place Formula 2 in an extraction tank, add water and soak for 2 hours. The mass of the water used for soaking should be 8 times the total mass of the medicinal materials in Formula 2. Heat and decoct for 2 hours, then filter. Add water to the residue and decoct for another 1.5 hours. Add water to the residue and decoct for another 1.5 hours. The mass of the water used for decoction should be 8 times the total mass of the medicinal materials in Formula 2. Filter, combine the filtrates from the two filtrations, let stand for 24 hours, then take the supernatant and filter. The filtrate is Solution 2. Step 4: Concentration. The solution obtained in Step 3 is concentrated to a fluid extract with a relative density of 1.10 to 1.15. The temperature of the fluid extract is 80°C. This step allows some of the solvent to evaporate, reducing the amount of ethanol consumed during alcohol precipitation. At the same time, the preliminary concentration also allows some poorly water-soluble inactive components to be precipitated and removed.

[0035] Step 5: Alcohol precipitation. Place the fluid extract obtained in Step 4 into an alcohol precipitation tank, cool to room temperature, add ethanol until the alcohol content reaches 60% by mass, stir evenly, and let stand for 24 hours. Take the supernatant and filter it through a 200-mesh sieve. Recover the ethanol from the filtrate to obtain Solution 3. The purpose of alcohol precipitation is to remove impurities and purify the solution. The principle of this method is based on the characteristic that the effective components of the drug in this invention, such as glycosides, organic acid salts, amino acids, and polysaccharides, are easily soluble in water and alcohol. Water is used for extraction, and the extract is concentrated. Appropriate ethanol is added, and after one or more precipitation cycles, insoluble substances are precipitated, finally yielding a clear liquid. The use of a 60% alcohol concentration employs a selective dissolution method for the effective components of the medicinal material, meaning that all effective components can be dissolved, and the alcohol-soluble content no longer increases with increasing alcohol concentration, while the alcohol-insoluble substances in the water extract are precipitated and removed.

[0036] Step Six: Concentration and Drying. Mix Solution One obtained in Step Two with Solution Three obtained in Step Five, and concentrate to an extract with a relative density of 1.20–1.25. Dry the extract at 80°C, 65–75°C, and 0.06–0.08 MPa under reduced pressure to obtain a dry extract. The extract at this concentration has a low water content, which is beneficial for the next step of reduced pressure drying and prevents the extract from gelatinizing and losing the active ingredients.

[0037] Step 7: Crush and sieve. Under 100,000-level purification conditions, crush the dry extract obtained in step 6 and pass it through an 80-mesh sieve to obtain the medicinal powder. Step 8: Granulation. Under 100,000-level cleanroom conditions, place the powder obtained in Step 7 into a trough mixer, add 90% to 95% (by volume) of ethanol aqueous solution and stir evenly. Granulate using an 18-mesh stainless steel sieve, dry at 65°C to 85°C, and granulate using a 20-mesh stainless steel sieve. Add 0.5% (by total mass) of magnesium stearate to the mixture. Example 3 A nutritional product for strengthening the spleen and kidneys and its preparation method, comprising the following steps: Step 1: Prepare the medicine. Weigh out the following ingredients according to the prescription: Cuscuta chinensis, Lycium barbarum, Achyranthes bidentata, Scrophularia ningpoensis, Rehmannia glutinosa, and Polygonatum sibiricum. Prepare the following formula: Cuscuta chinensis 13 parts, Lycium barbarum 6.5 parts, Achyranthes bidentata 6.5 parts, Scrophularia ningpoensis 10 parts, Rehmannia glutinosa 10 parts, Polygonatum sibiricum 6.5 parts. Next, weigh out the following ingredients according to the formula to prepare Formula 2: Euryale ferox, raspberry, privet fruit, ophiopogon japonicus and schisandra chinensis. The contents of Euryale ferox, raspberry, privet fruit, ophiopogon japonicus and schisandra chinensis are as follows: Euryale ferox 13 parts, raspberry 6.5 parts, privet fruit 10 parts, ophiopogon japonicus 6.5 parts and schisandra chinensis 6.5 parts.

[0038] Step Two, Extraction One: Place Formula One in an extraction tank, add water to soak for 2 hours, then heat and decoct. The mass of the water used for soaking should be 8 times the total mass of the medicinal materials in Formula One. After decoction for 1 hour, add 2 parts of Rhodiola rosea, continue heating for 1 hour, filter, add water to the residue and decoct again for 1.5 hours, then filter again. The mass of the water used for decoction again should be 8 times the total mass of the medicinal materials in Formula One. Combine the filtrates from the two filtrations, let stand for 24 hours, then filter the supernatant. The filtrate is Solution One. In addition to containing rhodioloside and various flavonoids, Rhodiola rosea is also rich in various amino acids, vitamins, and essential trace elements. Therefore, in order to ensure the full extraction of effective components and reduce the damage to trace elements during decoction, it is added later in the decoction process to reduce the high-temperature decoction time.

[0039] Step 3, Extraction 2: Place Formula 2 in an extraction tank, add water and soak for 2 hours. The mass of the water used for soaking should be 8 times the total mass of the medicinal materials in Formula 2. Heat and decoct for 2 hours, then filter. Add water to the residue and decoct for another 1.5 hours. Add water to the residue and decoct for another 1.5 hours. The mass of the water used for decoction should be 8 times the total mass of the medicinal materials in Formula 2. Filter, combine the filtrates from the two filtrations, let stand for 24 hours, then take the supernatant and filter. The filtrate is Solution 2. Step 4: Concentration. The solution obtained in Step 3 is concentrated to a fluid extract with a relative density of 1.10 to 1.15. The temperature of the fluid extract is 80°C. This step allows some of the solvent to evaporate, reducing the amount of ethanol consumed during alcohol precipitation. At the same time, the preliminary concentration also allows some poorly water-soluble inactive components to be precipitated and removed.

[0040] Step 5: Alcohol precipitation. Place the fluid extract obtained in Step 4 into an alcohol precipitation tank, cool to room temperature, add ethanol until the alcohol content reaches 60% by mass, stir evenly, and let stand for 24 hours. Take the supernatant and filter it through a 200-mesh sieve. Recover the ethanol from the filtrate to obtain Solution 3. The purpose of alcohol precipitation is to remove impurities and purify the solution. The principle of this method is based on the characteristic that the effective components of the drug in this invention, such as glycosides, organic acid salts, amino acids, and polysaccharides, are easily soluble in water and alcohol. Water is used for extraction, and the extract is concentrated. Appropriate ethanol is added, and after one or more precipitation cycles, insoluble substances are precipitated, finally yielding a clear liquid. The use of a 60% alcohol concentration employs a selective dissolution method for the effective components of the medicinal material, meaning that all effective components can be dissolved, and the alcohol-soluble content no longer increases with increasing alcohol concentration, while the alcohol-insoluble substances in the water extract are precipitated and removed.

[0041] Step Six: Concentration and Drying. Mix Solution One obtained in Step Two with Solution Three obtained in Step Five, and concentrate to an extract with a relative density of 1.20–1.25. Dry the extract at 80°C, 65–75°C, and 0.06–0.08 MPa under reduced pressure to obtain a dry extract. The extract at this concentration has a low water content, which is beneficial for the next step of reduced pressure drying and prevents the extract from gelatinizing and losing the active ingredients.

[0042] Step 7: Crush and sieve. Under 100,000-level purification conditions, crush the dry extract obtained in step 6 and pass it through an 80-mesh sieve to obtain the medicinal powder. Step 8: Granulation. Under 100,000-level cleanroom conditions, place the powder obtained in Step 7 into a trough mixer, add 90% to 95% (by volume) of ethanol aqueous solution and stir evenly. Granulate using an 18-mesh stainless steel sieve, dry at 65°C to 85°C, and granulate using a 20-mesh stainless steel sieve. Add 0.5% (by total mass) of magnesium stearate to the mixture. The above embodiments are only used to illustrate the technical solutions of this application, and are not intended to limit this application. Although this application has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that modifications can still be made to the technical solutions described in the foregoing embodiments, or equivalent substitutions can be made to some or all of the technical features therein. Such modifications or substitutions do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of this application.

Claims

1. A method for preparing a nutritional product that strengthens the spleen and kidneys, characterized in that, include: Step 1: Prepare the medicine. Weigh out the following ingredients according to the formula: Cuscuta chinensis, Lycium barbarum, Achyranthes bidentata, Scrophularia ningpoensis, Rehmannia glutinosa, and Polygonatum sibiricum to prepare the first prescription. Weigh out the following ingredients according to the formula: Euryale ferox, Rubus idaeus, Ligustrum lucidum, Ophiopogon japonicus, and Schisandra chinensis to prepare the second prescription. Step 2, Extraction 1: Place the first prescription in an extraction tank, add water to soak for 2 hours, heat and decoct. After decoction for 1 hour, add Rhodiola rosea and continue heating for 1 hour. Filter, add water to the residue and decoct for another 1.5 hours, then filter. Combine the filtrates from the two filtrations, let stand for 24 hours, then take the supernatant and filter. The filtrate is Solution 1. Step 3, Extraction 2: Place Formula 2 in an extraction tank, add water to soak for 2 hours, heat and decoct for 2 hours, then filter. Add water to the residue and decoct for another 1.5 hours, then filter. Combine the filtrates from the two filtrations, let stand for 24 hours, then take the supernatant and filter. The filtrate is Solution 2. Step 4: Concentration. Solution 2 obtained in Step 3 is concentrated to a fluid extract with a relative density of 1.10 to 1.15, and the temperature of the fluid extract is 80°C. Step 5: Alcohol precipitation. Place the fluid extract prepared in Step 4 into an alcohol precipitation tank, cool to room temperature, add ethanol until the alcohol content is 60% by mass, stir evenly, let stand for 24 hours, take the supernatant and filter it through a 200-mesh sieve, recover the ethanol from the filtrate, and obtain solution 3. Step 6: Concentration and drying. Mix solution 1 obtained in step 2 with solution 3 obtained in step 5, and concentrate to an extract with a relative density of 1.20 to 1.

25. The extract is dried under reduced pressure at 80°C, 65 to 75°C, and 0.06 to 0.08 MPa to obtain a dry extract. Step 7: Grind and sieve. Grind the dry extract obtained in Step 6 and pass it through an 80-mesh sieve to obtain the medicinal powder. Step 8: Granulation. Place the powder obtained in step 7 into a trough mixer, add 90% to 95% (by volume) of ethanol aqueous solution and stir evenly. Granulate using an 18-mesh stainless steel sieve, dry at 65°C to 85°C, and granulate using a 20-mesh stainless steel sieve. Add 0.5% (by total mass) of magnesium stearate to the mixture. In step one, the contents of Cuscuta chinensis, Lycium barbarum, Achyranthes bidentata, Scrophularia ningpoensis, Rehmannia glutinosa, and Polygonatum sibiricum in the prescription are as follows: Cuscuta chinensis 6-15 parts, Lycium barbarum 3-10 parts, Achyranthes bidentata 3-10 parts, Scrophularia ningpoensis 5-15 parts, Rehmannia glutinosa 5-15 parts, and Polygonatum sibiricum 3-20 parts. The content of Euryale ferox, Rubus idaeus, Ligustrum lucidum, Ophiopogon japonicus, and Schisandra chinensis in prescription two is as follows: Euryale ferox 6-20 parts, raspberry 3-10 parts, privet fruit 5-20 parts, dandelion 5-15 parts, ophiopogon japonicus 3-10 parts, schisandra chinensis 3-10 parts In step two, the amount of Rhodiola rosea added is 3 to 6 parts.

2. The method for preparing a spleen-strengthening and kidney-tonifying nutritional product according to claim 1, characterized in that, In step one, the contents of Cuscuta chinensis, Lycium barbarum, Achyranthes bidentata, Scrophularia ningpoensis, Rehmannia glutinosa, and Polygonatum sibiricum in prescription one are as follows: Cuscuta chinensis 13 parts, Lycium barbarum 5 parts, Achyranthes bidentata 6 parts, Scrophularia ningpoensis 10 parts, Rehmannia glutinosa 10 parts, and Polygonatum sibiricum 6.5 parts. The contents of the following ingredients in Prescription 2 are as follows: 12 parts of Euryale ferox, 6 parts of Rubus idaeus, 10 parts of Ligustrum lucidum, 6.5 parts of Ophiopogon japonicus, and 6.5 parts of Schisandra chinensis. In step two, the amount of Rhodiola rosea added is 5 parts.

3. The method for preparing a spleen-strengthening and kidney-tonifying nutritional product according to claim 1, characterized in that, In step two, the mass of water used for soaking is 8 to 10 times the total mass of the medicinal materials in prescription one, and the mass of water used for decocting the residue is 8 times the total mass of the medicinal materials in prescription one; in step three, the mass of water used for soaking is 8 to 10 times the total mass of the medicinal materials in prescription two, and the mass of water used for decocting the residue is 8 times the total mass of the medicinal materials in prescription two.

4. The method for preparing a spleen-strengthening and kidney-tonifying nutritional product according to claim 1, characterized in that, Steps seven through nine are performed under Class 100,000 cleanroom conditions.

5. A nutritional product for strengthening the spleen and kidneys, characterized in that: The spleen-strengthening and kidney-tonifying nutritional product is prepared by any one of the methods described in claims 1 to 4.