Accurate extraction equipment for nuclear medicine radiopharmaceuticals

Abstract

The invention relates to the technical field of tumor nuclide treatment instruments, in particular to nuclear medicine radiopharmaceutical accurate extraction equipment which comprises an injector and a base, a fixing groove is formed in one side of the base, a locking rod is rotatably connected to the side wall of the fixing groove, and a sliding block is vertically and slidably matched with the side wall of the base; the side, away from the base, of the sliding block is provided with a clamping groove corresponding to a push rod of an injector, the side, away from the fixing groove, of the sliding block is rotationally connected with a threaded rod, the middle of the threaded rod is in threaded fit with a fixing ring, the fixing ring is fixedly connected with the side wall of the base, a control assembly is arranged on the threaded rod, a displacement sensor is embedded in the sliding block, and a vibration assembly is arranged on the threaded rod. The motor drives the threaded rod to drive the sliding block to precisely control the displacement of the injector push rod so as to precisely extract the medicine, and meanwhile, residual medicine at the needle point is discharged through vibration force generated by instantaneous reverse rotation of the spring and the motor; therefore, the problems of medicine quantity judgment errors and residual medicine dripping pollution caused by the fact that medical staff wear protective equipment are solved.

Description

Technical Field

[0001] This invention relates to the field of tumor radionuclide therapy device technology, specifically to a precise extraction device for nuclear medicine radiopharmaceuticals. Background Technology

[0002] Radioactive nuclides are chemical elements or isotopes that have radioactive decay properties. Their unstable atomic nuclei can spontaneously emit radiation (such as alpha rays, beta rays, or gamma rays) and decay into stable nuclides, which are widely used in medical, scientific research and other fields.

[0003] When using radiopharmaceuticals, medical personnel must strictly adhere to radiation protection and aseptic techniques. First, they must wear appropriate personal protective equipment, such as lead aprons, lead goggles, and protective gloves, to minimize radiation exposure. Operations must be performed within a designated radiation protection area, using lead shielding or protective screens to isolate the radioactive source. Before operation, the drug information, including the radionuclide type, dosage, and patient details, must be carefully verified to ensure accuracy. When drawing the drug, a syringe, such as a disposable syringe, must be used. The required dose must be carefully drawn from the container to avoid splashing or environmental contamination. Aseptic techniques must be followed, operation time minimized, distance from the radioactive source increased, and shielding used to further reduce radiation risk. After completion, radioactive waste and contaminated equipment must be disposed of immediately and properly. The dosage, time, and operator information of the drug drawn must be recorded in detail to ensure patient safety and compliance with radiation protection regulations. In actual use, because medical staff need to wear complete protective equipment, the process of manually extracting medication is complicated by several factors. The obstruction of vision by goggles and reduced tactile sensitivity while wearing protective clothing increases the error in judging the amount of medication to be extracted. Furthermore, residual medication in the syringe needle after extraction can lead to an actual extraction volume higher than expected. This residual medication also poses a risk of dripping during syringe transfer, increasing the extent of radioactive contamination. Additionally, manually purging gas from the syringe can easily release radioactive medication, resulting in inaccurate dosage and increasing the risk of radioactive contamination on the hands of the medical staff.

[0004] Therefore, this invention proposes a precise extraction device for nuclear medicine radiopharmaceuticals to solve the above problems. Summary of the Invention

[0005] To address the aforementioned problems, this invention provides a precise extraction device for nuclear medicine radiopharmaceuticals. It uses a motor-driven threaded rod to precisely control the displacement of the syringe plunger, achieving accurate drug extraction. Simultaneously, it utilizes the vibration force generated by the instantaneous reverse rotation of a spring and motor to expel residual drug from the needle tip. This solves the problems of dosage error and residual drug dripping contamination caused by medical personnel wearing protective equipment.

[0006] To achieve the above objectives, the technical solution of the present invention is as follows: A precise extraction device for nuclear medicine radiopharmaceuticals includes a syringe and a base. A fixing groove is formed on one side of the base, and a locking rod is rotatably connected to the side wall of the fixing groove. A slider located on the same side of the fixing groove is vertically slidably fitted to the side wall of the base. A slot corresponding to the push rod of the syringe is formed on the side of the slider away from the base. A threaded rod is rotatably connected to the side of the slider away from the fixing groove. A fixing ring is threadedly fitted in the middle of the threaded rod. The fixing ring is fixedly connected to the side wall of the base. A control component is provided on the threaded rod for driving the threaded rod to rotate and thus pulling the slider to move in order to control the amount of drug extracted by the syringe. A displacement sensor is embedded in the slider. The displacement sensor signal is connected to a controller, which is embedded in the base. A vibration component is provided on the threaded rod for providing vibration force to the syringe after extraction to expel excess drug.

[0007] The technical principle of the above solution is as follows: The syringe is placed in the fixed groove, and the locking rod is rotated to fix the syringe by applying pressure to it. The controller controls the drive assembly to rotate the threaded rod. The threaded rod is restricted by the fixing ring to move only along its length. Therefore, the rotation of the threaded rod is converted into the linear motion of the slider through the fixing ring. The slider moves the syringe push rod away from the needle tip through the slot, creating a negative pressure inside the syringe and drawing the drug into it. During the slider's movement, the displacement sensor on the slider monitors the displacement in real time and sends the data to the controller. When the displacement reaches a preset value, the target amount of drug is extracted from the syringe, and the controller stops the motor. After extraction, the controller triggers the vibration assembly to cause the slider to move in a momentary reverse direction. This momentary reverse movement is transmitted to the push rod through the slot, causing the entire syringe to vibrate and expel any excess drug from the needle tip.

[0008] The above approach has the following beneficial effects: 1. This solution uses equipment to automatically control the extraction process, avoiding problems such as obstructed vision and reduced tactile sensation caused by medical staff wearing protective equipment, thereby improving the accuracy of drug dosage control; 2. This solution uses a vibration component to expel residual medication from the needle tip, ensuring not only the accuracy of the dosage but also making the actual dose injected into the patient closer to the preset value. 3. This method reduces the risk of environmental pollution and radiation spread caused by residual drug dripping by removing excess drug from the needle tip, and also avoids contamination of the hands of medical staff.

[0009] Furthermore, the control component includes a transmission cavity, which is fixedly connected to the side wall of the base and the transmission cavity and the slider are located on the same side of the base. A threaded rod passes through the transmission cavity and is rotatably connected to the corresponding side wall of the transmission cavity. A first gear located in the transmission cavity is threaded onto the threaded rod, and a second gear meshes with the first gear. The side wall of the second gear is rotatably connected to the inner wall of the transmission cavity. A motor is fixedly connected in the transmission cavity, and the motor is signal-connected to the controller. The output shaft of the motor is parallel to the threaded rod, and the other end of the motor output shaft is coaxially fixedly connected to the second gear.

[0010] Beneficial effects: The controller controls the rotation of the motor, and the motor output shaft drives the second gear to rotate. Since the second gear meshes with the first gear, it transmits the rotational motion to the first gear. The first gear is threadedly engaged with the threaded rod, driving the threaded rod to rotate. The rotation of the threaded rod drives the slider to move. The motor in the transmission cavity drives the threaded rod to rotate, realizing the precise movement of the slider. The controller adjusts the motor operation according to the displacement sensor signal to ensure precise control of the extraction volume.

[0011] Furthermore, the vibration component includes a spring, which is sleeved on the surface of the threaded rod. The two ends of the spring are fixedly connected to the fixed ring and the slider respectively on the side close to each other. When the slider moves to the position where the drug extraction meets the standard, the controller controls the motor to rotate in the opposite direction for 0.1-0.2 seconds.

[0012] Beneficial effects: The vibration force generated by the reverse rotation of the spring and motor is used to expel excess medication from the syringe after the required amount has been extracted. The vibration intensity is controlled by the reverse rotation time set by the controller. This effectively removes residual medication or air from the needle tip, ensuring that the actual amount of medication extracted is consistent with the expected amount, reducing medication waste and the risk of contamination, and improving the accuracy of the treatment dosage.

[0013] Furthermore, the base has scale lines on its side wall.

[0014] Beneficial effects: It helps medical staff to intuitively observe the extraction progress and dosage, provides visual reference, facilitates dosage verification during operation, and enhances the reliability and safety of operation.

[0015] Furthermore, the base and its components are all made of lead.

[0016] Beneficial effects: Utilizing lead's radiation shielding properties to block the radiation from radiopharmaceuticals protects medical personnel from radiation damage and improves the safety of the operating environment.

[0017] Furthermore, an elastic flap is provided at the bottom opening of the syringe.

[0018] Beneficial effects: The elastic flap at the bottom opening of the syringe opens during extraction and injection, and automatically closes when extraction and injection stop, preventing the medication in the syringe from being expelled during vibration and improving the accuracy of medication extraction.

[0019] Furthermore, the inner wall of the card slot is equipped with an anti-slip layer.

[0020] Beneficial effects: The anti-slip layer on the inner wall of the slot increases the friction between the slider and the push rod, preventing the push rod from slipping during extraction, ensuring stable power transmission, and reducing the error in drug extraction volume.

[0021] Furthermore, a buffer layer is provided at the end of the locking rod near the fixing groove.

[0022] Beneficial effects: The buffer layer provides elastic support when securing the syringe, reducing squeezing damage to the syringe and enhancing the stability of the fixation.

[0023] Furthermore, the surfaces of the first gear, the second gear, the threaded rod, and the retaining ring are all coated with polytetrafluoroethylene.

[0024] Beneficial effects: The low-friction properties of the polytetrafluoroethylene coating reduce wear between components and extend the service life of equipment.

[0025] Furthermore, the base has anti-slip textures on both sides along its length.

[0026] Beneficial effects: The anti-slip texture on both sides of the base increases the friction between the hand and the device, preventing the device from slipping during operation, improving grip stability, enhancing safety during operation, and avoiding the risk of drug spillage and radiation exposure caused by the device slipping.

[0027] Additional aspects and advantages of the invention will be set forth in part in the description which follows, and in part will be obvious from the description, or may be learned by practice of the invention. Attached Figure Description

[0028] Figure 1 This is an overall isometric view of an embodiment of the nuclear medicine radiopharmaceutical precision extraction device of the present invention; Figure 2 This is a side sectional view of the base of an embodiment of the nuclear medicine radiopharmaceutical precision extraction device of the present invention; Figure 3 This is a front sectional view of the transmission cavity in an embodiment of the nuclear medicine radiopharmaceutical precision extraction device of the present invention.

[0029] The reference numerals in the accompanying drawings of the instruction manual include: 1. syringe; 2. base; 3. fixing groove; 4. locking rod; 5. slider; 6. slot; 7. threaded rod; 8. retaining ring; 9. transmission cavity; 10. first gear; 11. motor; 12. output shaft; 13. second gear; 14. spring; 15. needle tip; 16. push rod. Detailed Implementation

[0030] The technical solution of the present invention will now be clearly and completely described with reference to the accompanying drawings. Obviously, the described embodiments are only some, not all, of the embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0031] In the description of this invention, it should be noted that the terms "center," "upper," "lower," "left," "right," "vertical," "horizontal," "inner," and "outer," etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are used only for the convenience of describing the invention and for simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on the invention. Furthermore, the terms "first," "second," and "third" are used for descriptive purposes only and should not be construed as indicating or implying relative importance.

[0032] In the description of this invention, it should be noted that, unless otherwise explicitly specified and limited, the terms "installation," "connection," and "linking" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in this invention based on the specific circumstances.

[0033] The following detailed description illustrates the specific implementation method: Example 1:

[0034] As attached Figure 1 As shown: A precise extraction device for radiopharmaceuticals in nuclear medicine includes a syringe 1 and a base 2. The side wall of the base 2 is provided with graduation lines, and the bottom opening of the syringe 1 is provided with an elastic flap. Due to the radioactivity of radiopharmaceuticals, medical personnel must strictly adhere to the principles of radiation protection and aseptic operation during the extraction process. Therefore, medical personnel need to wear a full set of protective equipment, such as lead aprons, lead glasses, and protective gloves, to reduce radiation exposure. After wearing protective equipment, the vision and tactile sensation of medical personnel will be affected by the protective equipment, which will lead to an increase in the error of medical personnel's judgment of the amount of drug extracted during manual drug extraction due to the obstruction of vision by the goggles and the weakening of tactile sensation after wearing protective clothing. To improve the accuracy of radiopharmaceutical extraction, as shown in the appendix... Figure 1 and attached Figure 2As shown, a fixing groove 3 is opened on one side of the base 2. A locking rod 4 is rotatably connected to the side wall of the fixing groove 3. A buffer layer is provided at the end of the locking rod 4 near the fixing groove 3. A slider 5 located on the same side of the fixing groove 3 is vertically slidably connected to the side wall of the base 2 through a sliding groove and a slide rail. A slot 6 corresponding to the push rod 16 of the syringe 1 is opened on the side of the slider 5 away from the base 2. An anti-slip layer is provided on the inner wall of the slot 6. A threaded rod 7 is rotatably connected to the side of the slider 5 away from the fixing groove 3. A fixing ring 8 is threaded in the middle of the threaded rod 7. The fixing ring 8 is welded to the side wall of the base 2. A control component is provided on the threaded rod 7 to drive the threaded rod 7 to rotate and thus pull the slider 5 to move to control the amount of drug drawn by the syringe 1. A displacement sensor is embedded in the slider 5. The displacement sensor is preferably a German Heidenhain MT 12 series magnetic scale. The displacement sensor signal is connected to a controller. The controller is preferably a Siemens S7-1200 series PLC. The controller is embedded in the base 2. As attached Figure 3 As shown, the control assembly includes a transmission cavity 9, which is welded to the side wall of the base 2. The transmission cavity 9 and the slider 5 are located on the same side of the base 2. A threaded rod 7 passes through the transmission cavity 9 and is rotatably connected to the corresponding side wall of the transmission cavity 9. A first gear 10 located inside the transmission cavity 9 is threaded onto the threaded rod 7. A second gear 13 meshes with the first gear 10. The side wall of the second gear 13 is rotatably connected to the inner wall of the transmission cavity 9. A motor 11 is welded inside the transmission cavity 9. The preferred model of the motor 11 is a Panasonic MINAS A6 series servo motor 11. The motor 11 is signal-connected to the controller. The output shaft 12 of the motor 11 is parallel to the threaded rod 7. The other end of the output shaft 12 of the motor 11 is coaxially welded to the second gear 13. The surfaces of the first gear 10, the second gear 13, the threaded rod 7, and the fixing ring 8 are all coated with polytetrafluoroethylene. The threaded rod 7 is equipped with a vibrating component for providing vibration to the syringe 1 after extraction to expel excess drug, as shown in the attached diagram. Figure 2 As shown, the vibration assembly includes a spring 14, which is sleeved on the surface of the threaded rod 7. The two ends of the spring 14 are welded to the fixed ring 8 and the slider 5 respectively on the same side. When the slider 5 moves to the position where the drug extraction meets the standard, the controller controls the motor 11 to rotate in the opposite direction for 0.1-0.2 seconds.

[0035] The specific implementation process is as follows: Medical staff put on radiation protection equipment such as lead aprons, lead glasses and protective gloves. Because wearing protective equipment will affect vision and hand touch, traditional manual extraction is prone to errors in judging the dosage. First, medical staff place the syringe 1 with an elastic valve into the fixing groove 3 of the base 2. The elastic valve opens during extraction and injection and closes automatically when the operation stops to prevent drug leakage. Then, the locking rod 4 is rotated. The buffer layer at the end of the locking rod 4 near the fixing groove 3 will contact the syringe 1, fixing the syringe 1 in the fixing groove 3. At the same time, the push rod 16 of the syringe 1 is inserted into the slot 6 of the slider 5. The anti-slip layer on the inner wall of the slot 6 increases the friction between the slider 5 and the push rod 16, preventing the push rod 16 from slipping during extraction, ensuring stable power transmission, and reducing the error in the amount of drug extracted. Next, medical staff set the target amount of medication to be extracted using the controller. When the medication extraction begins, the controller starts the motor 11 in the transmission chamber 9. The output shaft 12 of the motor 11 rotates, driving the second gear 13 to rotate. The second gear 13 drives the first gear 10, which meshes with it, to rotate. The first gear 10 and the threaded rod 7 are threaded together, causing the threaded rod 7 to move along the axial direction of the threaded rod 7. Since the middle part of the threaded rod 7 is rotatably connected to the fixed ring 8, and the fixed ring 8 is fixedly connected to the side wall of the base 2, the fixed ring 8 restricts the threaded rod 7 to move stably along the axial direction of the fixed ring 8. The movement of the threaded rod 7 causes the slider 5 to move linearly along the axial direction of the threaded rod 7. The slider 5 moves away from the fixed groove 3. The movement of the slider 5 pulls the push rod 16 of the syringe 1 to move synchronously through the slot 6. A negative pressure is generated inside the syringe 1, and the medication is drawn into the syringe 1. During this process, the displacement sensor sends the displacement data of slider 5 to the controller in real time. The controller controls the operation of motor 11 according to the displacement value corresponding to the preset target drug amount. When the displacement of slider 5 reaches the preset value, the amount of drug in syringe 1 reaches the target extraction amount. The controller controls motor 11 to stop moving, achieving precise extraction. At the same time, the scale lines on the side wall of base 2 can help medical staff to intuitively observe the extraction progress and drug amount, providing a visual reference, facilitating dosage verification during operation, and enhancing the reliability and safety of operation. After extraction, the actual amount of drug extracted may be higher than the expected amount due to residual drug in the needle tip 15 of syringe 1. Furthermore, there is a risk of residual drug dripping during transfer, increasing the contamination range of the radioactive drug. Therefore, when slider 5 moves to the target extraction position, the controller controls motor 11 to rotate in the reverse direction for 0.1-0.2 seconds. This reverse rotation of motor 11 drives the threaded rod 7 to rotate in the reverse direction, causing slider 5 to tend to move towards the fixed groove 3. After 0.1-0.2 seconds, motor 11 stops rotating in the reverse direction, and the elastic force of spring 14 causes slider 5 to undergo a momentary reverse motion. This momentary reverse motion of slider 5 is transmitted to push rod 16 through slot 6, causing syringe 1 to vibrate as a whole, expelling excess drug or air from the needle tip 15. The elastic flap automatically closes at this time to prevent drug leakage during vibration. This not only ensures the accuracy of the extracted drug dosage, making the actual dose injected into the patient closer to the preset value, but also reduces the risk of environmental pollution and radiation spread caused by residual drug dripping, and avoids contamination of the hands of medical personnel.

[0036] Example 2:

[0037] As attached Figure 1 As shown, the difference from Example 1 is that, due to the radioactive nature of the radiopharmaceutical, the equipment after extraction is easily contaminated by radioactive materials, which can lead to environmental pollution and radiation spread. In order to reduce radiation spread and improve the safety of drug extraction, the base 2 and the components on the base 2 are made of lead. The radiation shielding properties of lead are used to block the radiation of the radiopharmaceutical and improve the safety of the operating environment.

[0038] Example 3:

[0039] As attached Figure 1 As shown, the difference from Example 2 is that, since medical personnel need to wear complete protective equipment during the extraction of radiopharmaceuticals, the friction of the medical personnel's hands is reduced after wearing the protective clothing. In order to ensure the stability of the medical personnel's grip, the base 2 is provided with anti-slip textures on both sides along its length direction. The protective clothing increases the friction between the medical personnel's hands and the equipment, preventing the equipment from slipping during operation, avoiding the risk of drug splashing or radiation exposure caused by the equipment slipping, and enhancing the safety of the operation process.

[0040] Obviously, the above embodiments are merely illustrative examples for clear explanation and are not intended to limit the implementation. Those skilled in the art will recognize that other variations or modifications can be made based on the above description. It is neither necessary nor possible to exhaustively list all possible implementations here. However, obvious variations or modifications derived therefrom are still within the scope of protection of this invention.

Claims

1. A precise extraction device for nuclear medicine radiopharmaceuticals, comprising a syringe (1) and a base (2), characterized in that: A fixing groove (3) is opened on one side of the base (2). A locking rod (4) is rotatably connected to the side wall of the fixing groove (3). A slider (5) located on the same side of the fixing groove (3) is vertically slidably fitted on the side wall of the base (2). A slot (6) corresponding to the push rod (16) of the syringe (1) is opened on the side of the slider (5) away from the base (2). A threaded rod (7) is rotatably connected to the side of the slider (5) away from the fixing groove (3). A fixing ring (8) is threaded in the middle of the threaded rod (7). The fixing ring (8) is fixedly connected to the side wall of the base (2). A control component is provided on the threaded rod (7) for driving the threaded rod (7) to rotate and thus pull the slider (5) to move in order to control the amount of drug extracted by the syringe (1). A displacement sensor is embedded in the slider (5). The displacement sensor signal is connected to a controller. The controller is embedded in the base (2). A vibration component is provided on the threaded rod (7) for providing vibration force to the syringe (1) after extraction to expel excess drug.

2. The precise extraction device for nuclear medicine radiopharmaceuticals according to claim 1, characterized in that: The control component includes a transmission cavity (9), which is fixedly connected to the side wall of the base (2). The transmission cavity (9) and the slider (5) are located on the same side of the base (2). A threaded rod (7) passes through the transmission cavity (9) and is rotatably connected to the corresponding side wall of the transmission cavity (9). A first gear (10) located in the transmission cavity (9) is threadedly engaged on the threaded rod (7). A second gear (13) meshes on the first gear (10). The side wall of the second gear (13) is rotatably connected to the inner wall of the transmission cavity (9). A motor (11) is fixedly connected in the transmission cavity (9). The motor (11) is signal-connected to the controller. The output shaft (12) of the motor (11) is parallel to the threaded rod (7). The other end of the output shaft (12) of the motor (11) is coaxially fixedly connected to the second gear (13).

3. The precise extraction device for nuclear medicine radiopharmaceuticals according to claim 1, characterized in that: The vibration assembly includes a spring (14), which is sleeved on the surface of the threaded rod (7). The two ends of the spring (14) are fixedly connected to the fixed ring (8) and the slider (5) respectively on the same side. When the slider (5) moves to the position where the drug is extracted, the controller controls the motor (11) to rotate in the opposite direction for 0.1-0.2 seconds.

4. The precise extraction device for nuclear medicine radiopharmaceuticals according to claim 3, characterized in that: The base (2) has scale lines on its side wall.

5. The precise extraction device for nuclear medicine radiopharmaceuticals according to claim 4, characterized in that: The base (2) and the components on the base (2) are made of lead.

6. The precise extraction device for nuclear medicine radiopharmaceuticals according to claim 1, characterized in that: The syringe (1) has an elastic flap at the bottom opening.

7. The precise extraction device for nuclear medicine radiopharmaceuticals according to claim 1, characterized in that: The inner wall of the card slot (6) is provided with an anti-slip layer.

8. The precise extraction device for nuclear medicine radiopharmaceuticals according to claim 1, characterized in that: A buffer layer is provided at one end of the locking rod (4) near the fixing groove (3).

9. The precise extraction device for nuclear medicine radiopharmaceuticals according to claim 8, characterized in that: The surfaces of the first gear (10), the second gear (13), the threaded rod (7), and the retaining ring (8) are all coated with polytetrafluoroethylene.

10. The precise extraction device for nuclear medicine radiopharmaceuticals according to claim 9, characterized in that: The base (2) has anti-slip textures on both sides along its length.

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