A constant temperature infusion system and a control method thereof

Abstract

The application discloses a constant-temperature infusion system, which comprises a main heating constant-temperature unit, a terminal compensation heating unit and a main controller, is used for detecting the temperature of a medicinal liquid in an infusion bag and carrying out basic temperature heating, so that the medicinal liquid is at a set temperature, a pipeline section arranged close to a patient's intravenous injection point is used for detecting the temperature of the medicinal liquid and finally compensating the temperature of the medicinal liquid, and is connected with the main heating constant-temperature unit and the terminal compensation heating unit respectively; and the main controller is configured as. Through the double-stage heating control strategy combining "source basic heating" with "terminal accurate compensation", the application effectively solves the heat loss problem of the medicinal liquid in the long infusion pipeline conveying process, the main heating unit preliminarily heats, the terminal heating unit finely adjusts according to the real-time temperature, and the accuracy and stability of the temperature of the medicinal liquid when finally injected into the patient's body are ensured.

Description

Technical Field

[0001] This invention relates to the technical field of medical devices, and in particular to a constant temperature infusion system and its control method. Background Technology

[0002] In clinical treatment, many intravenously infused drugs (such as certain chemotherapy drugs, parenteral nutrition solutions, blood products, and large-volume fluids) need to be administered at temperatures close to body temperature to avoid problems such as chills, vascular irritation, changes in the physicochemical properties of the drugs, or decreased comfort in patients. Therefore, existing technologies have developed infusion pumps or syringe pumps with heating functions, which typically integrate a heating device into the drug solution container (such as a syringe barrel or infusion bag) or the adjacent tubing initiation.

[0003] However, such solutions have significant drawbacks: when the medication needs to travel a relatively long infusion tubing (e.g., 1 to 3 meters) to reach the patient's intravenous injection point, the medication continuously exchanges heat with the external environment as it flows through the tubing, resulting in heat loss. This temperature drop is particularly pronounced when the ambient temperature is low or the infusion rate is slow. This leads to a large difference between the temperature the medication is heated in the container and the actual temperature it ultimately reaches when injected into the patient, making precise isothermal infusion impossible. Existing technologies either ignore this problem or attempt to insulate or heat the entire tubing, but the latter suffers from high energy consumption, complex control, the risk of localized overheating, and poor flexibility. Summary of the Invention

[0004] In view of the above-mentioned problems with existing infusion systems, the aim is to provide a constant temperature infusion system.

[0005] The specific technical solution is as follows: A constant temperature infusion system, comprising: The main heating and temperature control unit is used to detect the temperature of the medicine solution in the infusion bag and to heat the base temperature so that the medicine solution is at the set temperature. The end-of-line heating unit is located in the tubing section near the patient's intravenous injection point and is used to detect the temperature of the medication solution and to perform final temperature compensation for the medication solution. The main controller is connected to the main heating and constant temperature unit and the terminal compensation heating unit, respectively. The main controller is configured as follows: Based on the temperature of the infusion bag detected by the main heating and temperature control unit, the main heating and temperature control unit is controlled to heat the medicine solution to a set temperature. Based on the temperature of the liquid medicine in the end pipeline section of the end compensation heating unit, the compensation heating power of the end compensation heating unit is controlled so that the temperature of the liquid medicine at the injection point approaches the target temperature. The set temperature is slightly higher than the target temperature.

[0006] As a further improvement and optimization of this solution, the pipeline section is an infusion tube located between the infusion bag and the injection needle; An injection pump is installed on the infusion tube downstream of the infusion end. The injection pump is connected to the main controller, which can control the injection speed of the drug solution according to the temperature of the drug solution at the end.

[0007] As a further improvement and optimization of this solution, the main heating and temperature control unit includes: A detachable upper shell and a lower shell, wherein a clamping cavity for clamping an infusion bag is formed between the upper shell and the lower shell; The inner walls of the upper and lower shells, facing away from the infusion bag, are sequentially provided with a pressure buffer layer, a temperature equalization layer, a heating layer, and a heat insulation layer.

[0008] As a further improvement and optimization of this solution, the temperature distribution layer is an aluminum alloy temperature distribution plate; The heating layer is an etched foil heating element that is attached to the aluminum alloy heat spreader. The buffer layer is attached to the medical thermally conductive silicone on the aluminum alloy heat spreader. The aluminum alloy heat spreader plate has multiple NTC sensors embedded in an array.

[0009] As a further improvement and optimization of this solution, the upper shell and the lower shell are connected by a magnetic attraction structure.

[0010] As a further improvement and optimization of this solution, the end-compensation heating unit includes: A left housing and a right housing, the left housing and the right housing being disposed opposite to each other and detachably connected, and a channel for the passage of the infusion tube being formed between the left housing and the right housing; The flexible electric heating film / temperature sensor is provided on the inner wall of the left shell / right shell. That is, when the flexible electric heating film is provided on the left shell, the temperature sensor is provided on the right shell, and vice versa.

[0011] As a further improvement and optimization of this solution, the temperature sensor is a flexible thin-film thermocouple.

[0012] As a further improvement and optimization of this solution, thermally conductive silicone pads are provided between the flexible electrothermal film, the flexible thin-film thermocouple, and the infusion tube.

[0013] A method for controlling constant-temperature infusion, characterized in that it includes any one of the constant-temperature infusion systems described above, and the control method includes: S1: Input the target temperature into the main controller, and make the main controller control the main heating control unit to heat the medicine in the infusion bag and stabilize the medicine to the set temperature; S2: The injection pump operates and delivers the medication from the infusion bag to the injection needle through the infusion tube; S3: When the end-compensation heating unit detects that the temperature of the injected drug solution is lower than the target temperature, the end-compensation heating unit transmits the signal to the main controller, so that the main controller increases the heating power of the end-compensation heating unit, thereby bringing the temperature of the injected drug solution closer to the target temperature. When the end-compensation heating unit detects that the temperature of the injected drug solution is higher than the target temperature, the end-compensation heating unit transmits the signal to the main controller, so that the main controller reduces or turns off the heating power of the end-compensation heating unit, thereby bringing the temperature of the injected drug solution closer to the target temperature.

[0014] As a further improvement and optimization of this solution, in step S3, when the end-compensation heating unit detects that the temperature of the end-injected drug solution is lower or higher than the target temperature signal, the main controller reduces the power of the injection pump to reduce the flow rate of the drug solution in the infusion tube.

[0015] The positive effects of the above technical solution compared with the existing technology are: This invention effectively solves the problem of heat loss of medication during long infusion pipeline transportation by adopting a two-stage heating control strategy that combines "basic heating at the source" with "precise compensation at the end". The main heating unit performs initial heating, and the end heating unit makes fine adjustments according to the real-time temperature, ensuring the accuracy and stability of the temperature of the medication when it is finally injected into the patient. This overcomes the defects of existing technologies, such as uneven heating, high energy consumption and risk of local overheating, and achieves efficient and safe constant temperature infusion.

[0016] When the terminal temperature deviates from the target value, this invention can not only adjust the heating power, but also change the heat exchange time of the drug solution in the pipeline by adjusting the infusion rate, thereby providing a faster and more flexible temperature regulation method and enhancing the system's adaptability and control accuracy in response to different ambient temperatures and infusion rates. Attached Figure Description

[0017] Fig. 1 This is a schematic diagram of the structure of a constant temperature infusion system according to the present invention; Fig. 2 This is a schematic diagram of the main heating and temperature control unit of a constant temperature infusion system according to the present invention; Fig. 3 This is a schematic diagram of the end-compensation heating unit of a constant temperature infusion system according to the present invention; In the attached diagram: 1. Main controller; 2. Main heating and thermostat unit; 3. Injection pump; 4. End-compensation heating unit; 5. Infusion bag; 6. Infusion tubing; 7. Injection needle; 21. Upper shell; 22. Lower shell; 23. Clamping cavity; 24. Insulation layer; 25. Heating layer; 26. Temperature equalization layer; 27. Pressure buffer layer; 41. Left shell; 42. Right shell; 43. Flexible electric heating film; 44. Channel; 45. Thermally conductive silicone pad; 46. Temperature sensor. Detailed Implementation

[0018] The technical solution of the present invention will now be clearly and completely described with reference to the accompanying drawings. Obviously, the described embodiments are only some, not all, of the embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0019] In the description of this invention, it should be noted that terms such as "center," "upper," "lower," "left," "right," "vertical," "horizontal," "inner," and "outer," etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are used only for the convenience of describing this invention and for simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this invention. Furthermore, terms such as "first," "second," and "third" are used for descriptive purposes only and should not be construed as indicating or implying relative importance.

[0020] In the description of this invention, it should be noted that, unless otherwise explicitly specified and limited, the terms "installation," "connection," and "joining" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in this invention based on the specific circumstances.

[0021] Fig. 1 This is a schematic diagram of the structure of a constant temperature infusion system according to the present invention; Fig. 2 This is a schematic diagram of the main heating and temperature control unit of a constant temperature infusion system according to the present invention; Fig. 3 This is a schematic diagram of the end-compensation heating unit of a constant-temperature infusion system according to the present invention, as shown below. Figs. 1-3The diagram illustrates a preferred embodiment of a constant-temperature infusion system, comprising: a main heating and temperature control unit 2, a terminal compensation heating unit 4, and a main controller 1. The main controller 1 detects the temperature of the medication solution within the infusion bag 5 and heats it to a base temperature to maintain the solution at a set temperature. A tubing section located near the patient's intravenous injection point detects the medication solution temperature and performs final temperature compensation. The main controller 1 is connected to both the main heating and temperature control unit 2 and the terminal compensation heating unit 4. The main controller 1 is configured to: control the main heating and temperature control unit 2 to heat the medication solution to the set temperature based on the temperature of the infusion bag 5 detected by the main heating and temperature control unit 2; and control the compensation heating power of the terminal compensation heating unit 4 based on the medication solution temperature at the terminal tubing section to bring the temperature of the medication solution at the injection point closer to the target temperature. The set temperature is slightly higher than the target temperature to compensate for heat loss through the tubing section, thus bringing the final medication solution closer to the target temperature.

[0022] This application employs a dual-stage heating control strategy combining "basic heating at the source" and "precise compensation at the end," which effectively solves the problem of heat loss during the delivery of medication in a long infusion tubing with six channels. The main heating unit performs initial heating, while the end heating unit makes fine adjustments based on the real-time temperature, ensuring the accuracy and stability of the medication temperature when it is finally injected into the patient. This overcomes the shortcomings of existing technologies, such as uneven heating, high energy consumption, and the risk of local overheating, and achieves efficient and safe constant-temperature infusion.

[0023] Furthermore, in a preferred embodiment, the tubing section is an infusion tube 6 located between the infusion bag 5 and the injection needle 7. An injection pump 3 is installed on the infusion tube 6 downstream of the infusion end. The injection pump 3 is connected to the main controller 1, which can control the injection rate of the medication based on the temperature at the end of the infusion. By introducing the injection pump 3 and linking it with the main controller 1, the system achieves coordinated control of temperature and flow rate. When the end temperature deviates from the target value, not only can the heating power be adjusted, but the heat exchange time of the medication in the tubing can also be changed by adjusting the infusion rate. This provides a faster and more flexible temperature regulation method, enhancing the system's adaptability and control accuracy to different ambient temperatures and infusion rates.

[0024] Furthermore, as a preferred embodiment, the main heating and temperature control unit 2 includes: a detachably connected upper shell 21 and a lower shell 22, with a clamping cavity 23 formed between the upper shell 21 and the lower shell 22 for clamping the infusion bag 5; wherein, a pressure buffer layer 27, a temperature equalization layer 26, a heating layer 25, and a heat insulation layer 24 are sequentially arranged on the inner walls of the upper shell 21 and the lower shell 22, facing away from the infusion bag 5 and extending outward. The modular design of the clamping cavity 23 facilitates the installation and replacement of the infusion bag 5. The use of a multi-layer composite structure (pressure buffer, temperature equalization, heating, and heat insulation) ensures both the uniformity and efficiency of heating (through the temperature equalization layer 26) and improves the safety of use (the pressure buffer layer 27 prevents damage to the infusion bag, and the heat insulation layer 24 prevents burns from overheating of the outer shell), achieving efficient, safe, and user-friendly heating.

[0025] Furthermore, in a preferred embodiment, the temperature distribution layer 26 is an aluminum alloy temperature distribution plate; the heating layer 25 is an etched foil heating element attached to the aluminum alloy temperature distribution plate; and the buffer layer is a medical thermally conductive silicone attached to the aluminum alloy temperature distribution plate. Multiple NTC sensors are embedded in an array on the aluminum alloy temperature distribution plate. Using an aluminum alloy temperature distribution plate combined with an etched foil heating element enables rapid, large-area, and uniform heat conduction. The medical thermally conductive silicone, as a buffer layer, combines flexibility and thermal conductivity, protecting the infusion bag 5 while ensuring efficient heat transfer. The arrayed NTC sensors enable multi-point precise monitoring of the surface temperature of the infusion bag 5, providing the main controller 1 with more comprehensive and accurate temperature feedback data, thereby improving the temperature control accuracy of the basic heating.

[0026] Furthermore, in a preferred embodiment, the upper housing 21 and the lower housing 22 are connected by a magnetic attraction structure. This magnetic connection makes the opening and closing of the main heating unit extremely simple and quick, eliminating the need for complex mechanical latches, thus improving the operational efficiency and experience for medical personnel, while also facilitating cleaning and maintenance.

[0027] Further, as a preferred embodiment, the end-compensation heating unit 4 includes a left housing 41 and a right housing 42, which are disposed opposite to each other and detachably connected, and a channel 44 is formed between the left housing 41 and the right housing 42 for the passage of the infusion tube 6; wherein, a flexible electric heating film 43 and a temperature sensor 46 are disposed on the inner wall of the left housing 41 / right housing 42, that is, when the flexible electric heating film 43 is disposed on the left housing 41, the temperature sensor 46 is disposed on the right housing 42, and when the temperature sensor 46 is disposed on the left housing 41, the flexible electric heating film 43 is disposed on the right housing 42. The split housing design facilitates quick wrapping or detachment from the infusion tube 6 and provides flexible installation. Separating the flexible electric heating film 43 and the temperature sensor 46 on opposite sides of the channel 44 allows for more direct and accurate execution of heating and temperature measurement functions, reduces mutual interference, and results in a simple and reliable structure.

[0028] Preferably, the left housing 41 and the right housing 42 can be connected by a magnetic or snap-fit ​​structure.

[0029] Furthermore, as a preferred embodiment, the temperature sensor 46 is a flexible thin-film thermocouple. Flexible thin-film thermocouples are characterized by their thinness, flexibility, and fast response, allowing them to conform well to the wall of the infusion tube 6, achieving efficient heat conduction and accurate temperature measurement between the thermocouple and the medication without affecting the flow of the medication.

[0030] Furthermore, as a preferred embodiment, a thermally conductive silicone pad 45 is provided between the flexible heating film 43 and the flexible thin-film thermocouple and the infusion tube 6. The thermally conductive silicone pad 45 fills the gap between the heating film / sensor and the cylindrical infusion tube 6, improving the contact thermal resistance, ensuring efficient heat transfer to the drug solution and accurate temperature feedback, while its elasticity also plays a certain buffering and protective role, preventing the tube from being flattened and affecting the infusion.

[0031] A method for controlling constant-temperature infusion, characterized in that it includes any one of the above-mentioned constant-temperature infusion systems, and the control method includes: S1: Input the target temperature into the main controller 1, and make the main controller control the main heating control unit to heat the medicine in the infusion bag 5 and stabilize the medicine to the set temperature; S2: The syringe pump 3 operates and delivers the medicine solution in the infusion bag 5 through the infusion tube 6 toward the injection needle 7; S3: When the end compensation heating unit 4 detects that the temperature of the injected liquid at the end is lower than the target temperature, the end compensation heating unit 4 transmits the signal to the main controller 1 so that the main controller 1 increases the heating power of the end compensation heating unit 4, thereby making the temperature of the injected liquid approach the target temperature. When the end-compensation heating unit 4 detects that the temperature of the injected drug solution is higher than the target temperature, the end-compensation heating unit 4 transmits the signal to the main controller 1, so that the main controller 1 reduces or turns off the heating power of the end-compensation heating unit 4, thereby bringing the temperature of the injected drug solution closer to the target temperature.

[0032] The control method of this application forms a closed-loop control logic of "setting-monitoring-feedback-adjustment". In particular, the real-time feedback and dynamic compensation of the terminal temperature is the core to ensure that the final injection temperature is accurate and constant. Combined with the optional flow rate adjustment, a multi-dimensional control strategy is formed, which enables the system to intelligently and adaptively cope with various disturbance factors (such as changes in ambient temperature, changes in infusion rate, etc.), and realizes a stable, reliable and high-precision constant temperature infusion process.

[0033] Furthermore, as a preferred embodiment, in step S3, when the end-compensation heating unit 4 detects a signal that the temperature of the end-injected drug solution is lower or higher than the target temperature, the main controller 1 reduces the power of the injection pump 3 to reduce the flow rate of the drug solution in the infusion tube 6. Specifically, when the end temperature is too low, the flow rate is reduced to increase the heating time of the drug solution by the end-compensation heating unit 4, and the heating power of the end heating unit is increased to quickly raise the temperature of the end-injected drug solution to approach the target temperature. When the end temperature is too high, the flow rate is reduced to increase the heat exchange and dissipation of the drug solution with the outside through the infusion tube 6, and the power of the end heating unit is reduced or turned off to quickly bring the temperature of the end-injected drug solution close to the target temperature.

[0034] The above description is merely a preferred embodiment of the present invention and does not limit the implementation and protection scope of the present invention. Those skilled in the art should realize that any equivalent substitutions and obvious changes made based on the description and illustrations of the present invention should be included within the protection scope of the present invention.

Claims

1. A constant-temperature infusion system, characterized in that, include: The main heating and temperature control unit is used to detect the temperature of the medicine solution in the infusion bag and to heat the base temperature so that the medicine solution is at the set temperature. The end-of-line heating unit is located in the tubing section near the patient's intravenous injection point and is used to detect the temperature of the medication solution and to perform final temperature compensation for the medication solution. The main controller is connected to the main heating and constant temperature unit and the terminal compensation heating unit, respectively. The main controller is configured as follows: Based on the temperature of the infusion bag detected by the main heating and constant temperature unit, the main heating and constant temperature unit is controlled to heat the medicine solution to a set temperature. Based on the temperature of the liquid medicine in the end pipeline section of the end compensation heating unit, the compensation heating power of the end compensation heating unit is controlled so that the temperature of the liquid medicine at the injection point approaches the target temperature. The set temperature is slightly higher than the target temperature.

2. The constant temperature infusion system according to claim 1, characterized in that, The tubing section is an infusion tube located between the infusion bag and the injection needle; An injection pump is installed on the infusion tube downstream of the infusion end. The injection pump is connected to the main controller, which can control the injection speed of the drug solution according to the temperature of the drug solution at the end.

3. The constant temperature infusion system according to claim 1, characterized in that, The main heating and temperature control unit includes: A detachable upper shell and a lower shell, wherein a clamping cavity for clamping an infusion bag is formed between the upper shell and the lower shell; The inner walls of the upper and lower shells, facing away from the infusion bag, are sequentially provided with a pressure buffer layer, a temperature equalization layer, a heating layer, and a heat insulation layer.

4. The constant temperature infusion system according to claim 3, characterized in that, The temperature distribution layer is an aluminum alloy temperature distribution plate; The heating layer is an etched foil heating element that is attached to the aluminum alloy heat spreader. The buffer layer is attached to the medical thermally conductive silicone on the aluminum alloy heat spreader. The aluminum alloy heat spreader plate has multiple NTC sensors embedded in an array.

5. The constant temperature infusion system according to any one of claims 2-4, characterized in that, The upper housing and the lower housing are connected by a magnetic attraction structure.

6. The constant temperature infusion system according to claim 2, characterized in that, The end-compensation heating unit includes: A left housing and a right housing, the left housing and the right housing being disposed opposite to each other and detachably connected, and a channel for the passage of the infusion tube being formed between the left housing and the right housing; The flexible electric heating film / temperature sensor is provided on the inner wall of the left shell / right shell. That is, when the flexible electric heating film is provided on the left shell, the temperature sensor is provided on the right shell, and vice versa.

7. The constant temperature infusion system according to claim 6, characterized in that, The temperature sensor is a flexible thin-film thermocouple.

8. The constant temperature infusion system according to claim 7, characterized in that, A thermally conductive silicone pad is provided between the flexible electrothermal film, the flexible thin-film thermocouple, and the infusion tube.

9. A method for controlling constant temperature infusion, characterized in that, The constant temperature infusion system according to any one of claims 2-8, wherein the control method includes: S1: Input the target temperature into the main controller, and make the main controller control the main heating control unit to heat the medicine in the infusion bag and stabilize the medicine to the set temperature; S2: The injection pump operates and delivers the medication from the infusion bag to the injection needle through the infusion tube; S3: When the end-compensation heating unit detects that the temperature of the injected drug solution is lower than the target temperature, the end-compensation heating unit transmits the signal to the main controller, so that the main controller increases the heating power of the end-compensation heating unit, thereby bringing the temperature of the injected drug solution closer to the target temperature. When the end-compensation heating unit detects that the temperature of the injected drug solution is higher than the target temperature, the end-compensation heating unit transmits the signal to the main controller, so that the main controller reduces or turns off the heating power of the end-compensation heating unit, thereby bringing the temperature of the injected drug solution closer to the target temperature.

10. The constant temperature infusion control method according to claim 9, characterized in that, In step S3, when the end-compensation heating unit detects a signal that the temperature of the end-injected drug solution is lower or higher than the target temperature, the main controller reduces the power of the injection pump to reduce the flow rate of the drug solution in the infusion tube.

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