一种抗原表位肽及其制备的牙鲆黏蛋白Muc13特异性抗体
By preparing a Muc13-specific antibody for turbot, the problem of recognizing Muc13 protein in fish was solved, enabling specific labeling and localization of mucus cells, and promoting research on mucosal immune defense and disease control in fish.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- OCEAN UNIV OF CHINA
- Filing Date
- 2026-04-29
- Publication Date
- 2026-07-17
AI Technical Summary
Current technologies lack antibodies that can specifically recognize fish Muc13 protein, making it difficult to accurately locate and quantify fish Muc13 at the protein level, which hinders the research progress on fish mucosal immune defense mechanisms.
Muc13-specific antibodies against turbot were prepared by screening B-cell antigenic epitope peptides and conjugating them with a vector, and then immunizing animals to prepare monoclonal antibodies for tracing Muc13-positive mucous cells in mucosal tissues.
This study enabled the specific labeling and localization of mucus cells, allowing for in-depth exploration of the function of mucus cells in the mucosal immune defense of turbot, and providing an important tool for fish immunology research and disease control.
Smart Images
Figure CN122103300B_ABST