Artemisia argyi oil antibacterial microcapsule, preparation method and application

Abstract

This invention discloses an antibacterial microcapsule of Artemisia argyi oil, its preparation method, and its application. The preparation method includes wall material solution preparation, fine emulsion preparation, coagulation reaction, cross-linking curing, and post-treatment. The wall material solution includes a gelatin aqueous solution and a gum arabic aqueous solution. Artemisia argyi oil and gelatin solution are mixed and homogenized under high pressure microfluidic jet to obtain a fine emulsion. Gum arabic solution is added to the fine emulsion for coagulation reaction. Genipin aqueous solution is added as a cross-linking agent after cooling. After cross-linking curing, the microcapsule is centrifuged, washed, and freeze-dried to obtain Artemisia argyi oil antibacterial microcapsule powder. The high-pressure microfluidic jet homogenization technology results in high encapsulation efficiency and uniform particle size of the microcapsules. The use of genipin improves the thermal stability of the microcapsules. This makes the release of the core material more gradual and prolonged, and the release kinetics are more in line with the Fick diffusion mechanism, enabling long-lasting antibacterial effects. The low temperature rise during the high-pressure microfluidic jet homogenization process helps protect the heat-sensitive active ingredients in Artemisia argyi oil.

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