A process for optimizing extraction of total flavonoids from stems and leaves of houttuynia cordata based on response surface methodology

By optimizing the extraction process of total flavonoids from the stems and leaves of Houttuynia cordata using response surface methodology, the problem of low extraction rate was solved, achieving efficient flavonoid extraction, improving resource utilization and reducing production costs.

CN122124151APending Publication Date: 2026-06-02HUBEI YIYANG BIOTECHNOLOGY CO LTD +1
View PDF 0 Cites 0 Cited by

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
HUBEI YIYANG BIOTECHNOLOGY CO LTD
Filing Date
2026-02-10
Publication Date
2026-06-02

AI Technical Summary

Technical Problem

The existing technology has a low flavonoid extraction rate from the stems and leaves of Houttuynia cordata, which leads to resource waste and high production costs, making it difficult to achieve industrial utilization.

Method used

The extraction process of total flavonoids from the stems and leaves of Houttuynia cordata was optimized using response surface methodology. Through single-factor experiments and response surface design, the optimal extraction conditions, including ethanol concentration, extraction temperature, extraction time, and liquid-to-solid ratio, were determined. A second-order polynomial regression model was established to optimize the combination of extraction parameters.

Benefits of technology

The extraction rate of flavonoids from the stems and leaves of Houttuynia cordata was improved to 32.47±0.05 mg/g. The optimization results were stable and reliable, providing a theoretical basis and laying the foundation for the full utilization of resources and cost reduction.

✦ Generated by Eureka AI based on patent content.

Smart Images

  • Figure CN122124151A_ABST
    Figure CN122124151A_ABST
Patent Text Reader

Abstract

This invention discloses a process for optimizing the extraction of total flavonoids from Houttuynia cordata stems and leaves based on response surface methodology, relating to the field of natural product extraction technology. The method includes the following steps: Step 1, obtaining dried and pulverized Houttuynia cordata stem and leaf powder; Step 2, extracting total flavonoids from the powder using ultrasound, selecting ethanol concentration, extraction temperature, extraction time, and liquid-to-solid ratio as single-factor experiments, and employing response surface methodology with total flavonoid content as the response value to establish a second-order polynomial regression model to predict the optimal extraction conditions; Step 3, determining the optimized extraction parameter combination based on the model; Step 4, performing the extraction operation according to the optimized extraction parameter combination. This invention utilizes response surface methodology to optimize the extraction process of total flavonoids from Houttuynia cordata stems and leaves, determining a process that can effectively extract flavonoids from Houttuynia cordata stems and leaves, providing a theoretical basis for the research and utilization of flavonoids from Houttuynia cordata stems and leaves.
Need to check novelty before this filing date? Find Prior Art