Whitening compositions comprising dibunaphyline tobacco extract and uses thereof

Abstract

This application relates to a skin-whitening composition comprising *Tobacco de Burgh* extract and its use. According to one aspect of the composition, melanin production pathways are regulated by reducing the expression of tyrosinase protein, thereby exhibiting both intracellular and extracellular melanin production inhibitory activity. Therefore, this application provides a cosmetic composition for skin whitening, a health food composition for skin whitening, and a pharmaceutical composition for the prevention or treatment of hypermelanosis, comprising *Tobacco de Burgh* extract as an active ingredient.