A keratin composite active fiber membrane for hair care and a method for preparing the same

Abstract

The present application relates to the technical field of hair care products, and particularly relates to a keratin composite active fiber film for hair care and a preparation method thereof. A conventional hair film product is in a paste form, needs to be left for a long time or heated, and the paste product is unevenly distributed, has a strong greasy feeling, and hair needs to be washed and dried again. In view of the above problems, the present application provides a keratin composite active fiber film for hair care, characterized by a layered structure, and comprising at least one base adhesion layer and at least one core repair layer from bottom to top, and the adjacent base adhesion layer and core repair layer are interfaced and composited through physical interaction and / or chemical bonding. The keratin composite active fiber film exists in a dry film form, can be directly attached to wet hair when used, the active ingredients have a concentrated effect, the repair effect is better, heating is not needed, long time staying and re-washing are not needed, and the hair can be dried after use, so that the convenience, comfort and efficiency of use are greatly improved.

Description

Technical Field

[0001] This invention relates to the field of hair care product technology, specifically to a keratin composite active fiber membrane for hair care and its preparation method. Background Technology

[0002] The main component of hair is keratin, and its health depends primarily on the integrity of the hair cuticle and the structure of keratin in the cortex. However, in daily life, activities such as perming, dyeing, UV exposure, and using chemical hair care products can all damage the keratin structure of hair, leading to a series of problems such as roughness, dryness, breakage, and split ends. Therefore, repairing damaged hair has become a key issue that urgently needs to be addressed in the field of hair care, and supplementing with exogenous keratin is one of the effective strategies for repairing damaged hair.

[0003] Wool keratin, due to its high structural similarity to hair keratin, exhibits a unique role in hair repair. Wool keratin is rich in cysteine, which, during hydrolysis, generates active peptides containing free sulfhydryl groups (-SH). When applied to damaged hair, these low-molecular-weight peptides exhibit two key modes of action:

[0004] Cortical Penetration and Bond Repair: Hydrolyzed keratin peptides can penetrate into the cortex by exploiting structural defects in the hair cuticle. Inside the fiber, the thiol groups in the peptides can undergo thiol-disulfide bond exchange reactions with broken disulfide bonds in hair keratin, theoretically partially rebuilding and stabilizing the three-dimensional network structure of keratin. This process is significant for restoring the mechanical properties of hair, such as improving its tensile strength and fatigue resilience.

[0005] Surface deposition and film protection: Unpenetrated keratin components adsorb and deposit on the hair surface, forming a continuous biopolymer film. This film effectively smooths damaged and raised hair cuticles, reduces the dynamic coefficient of friction between fibers, and increases hair shine. Simultaneously, this film acts as a physical barrier, reducing moisture loss from the hair shaft and offering some protection against further damage from external environmental factors such as UV rays and mechanical friction.

[0006] Currently, most hair care products containing keratin on the market are in the form of shampoos, conditioners, and hair masks, but these products have many limitations:

[0007] Poor adhesion: The keratin molecules in traditional products are relatively large and have difficulty penetrating into the hair shaft. Most of them only adhere to the surface of the hair, and the retention after rinsing is limited, resulting in poor durability.

[0008] Limited repair efficacy: Most products focus on achieving immediate smoothness, but lack the ability to deeply repair keratin voids and rebuild disulfide bonds to fundamentally improve hair strength and elasticity.

[0009] Weak protective function: lacks effective synergistic protection against factors that cause hair to become dry and brittle, such as heat damage and oxidative stress (e.g., ultraviolet radiation).

[0010] Inconvenient to use: Some hair masks require a long time to leave on or be heated, and cream-type products may have problems such as uneven distribution and a greasy feeling.

[0011] In view of the above problems, there is an urgent market demand for a keratin-based hair care material that can adhere efficiently, repair deeply, nourish and protect, and is easy to use. Summary of the Invention

[0012] The problems with existing technologies are that conventional hair mask products are in paste form, requiring a long time to leave on or to be heated, and the paste-like products are unevenly distributed and have a strong greasy feeling, requiring the hair to be washed and dried again. To address these problems, this invention provides a keratin composite active fiber membrane for hair care, characterized by a layered structure comprising at least one base adhesion layer and at least one core repair layer from bottom to top, with adjacent base adhesion layers and core repair layers forming an interfacial composite through physical interactions and / or chemical bonds;

[0013] The substrate adhesion layer is formed by casting; the core repair layer is formed by casting or electrospinning.

[0014] The raw material used for the substrate adhesion layer is a homogeneous mixture of wool keratin and cationic cellulose polymers (such as polyquaternium-10) in alkaline Tris-HCl buffer or water.

[0015] The raw materials used in the core repair layer are a uniform dispersion of wool keratin, hydrolyzed silk fibroin, and active ingredients in an ethanol aqueous solution containing acetic acid or 1,1,1,3,3,3-hexafluoroisopropanol (HFIP). The molecular weight of hydrolyzed silk fibroin is <10 kDa, and the molecular weight of wool keratin is 5 kDa~40 kDa.

[0016] Preferably, the molecular weight of wool keratin is 10~30 kDa.

[0017] Preferably, the pH of the alkaline Tris-HCl buffer solution is 8.5.

[0018] Preferably, the mass ratio of wool keratin to cationic fiber polymer in the raw materials used for the base adhesion layer is 1:1 to 3:1.

[0019] Preferably, the mass ratio of wool keratin to hydrolyzed silk fibroin and active ingredients in the raw materials used in the core repair layer is (8-20):(5-12):(1-5).

[0020] Preferably, the thickness of the substrate adhesion layer is 15-60 μm.

[0021] Preferably, the thickness of the core repair layer is 40-150 μm.

[0022] Preferably, the active ingredients include one or more of cystine, panthenol, amino silicone oil, vitamin E, polydimethylsiloxane alcohol, light stabilizer, and natural plant essential oils.

[0023] Preferably, the preparation method of the keratin composite active fiber membrane for hair care includes the following steps:

[0024] (1) According to the formula, wool keratin and cationic fiber polymer were added to alkaline Tris-HCl buffer, and purified by dialysis (the molecular weight cutoff of the dialysis membrane is 8-14 kDa) to obtain a uniform substrate adhesion solution.

[0025] (2) Dissolve keratin and hydrolyzed silk fibroin in HFIP or an ethanol aqueous solution containing acetic acid according to the formula amount, stir evenly, add active ingredients, and continue stirring until uniform to obtain a uniform core repair solution.

[0026] (3) The substrate adhesion liquid is poured into the mold and dried to form the substrate adhesion layer. Then, the core repair liquid is formed on the surface of the substrate adhesion layer by pouring or electrospinning to form the core repair layer, resulting in a composite film. After ultraviolet sterilization, it is packaged into a product for sale using aluminum foil film.

[0027] Preferably, step (3) in the preparation process of the keratin composite active fiber membrane can also be carried out in the following manner:

[0028] The base adhesion liquid is poured into a mold and dried to form a base adhesion layer. Then, the core repair liquid is formed on the surface of the base adhesion layer by pouring or electrospinning to form a core repair layer, resulting in a composite film. The composite film is then subjected to high-temperature thermal crosslinking (high-temperature thermal crosslinking method is high-temperature baking or fumigation with genipin aqueous solution). After cooling, the film is removed and cut into keratin composite active fiber films (hair tie film) of the required size. After ultraviolet sterilization, it is packaged in aluminum foil film as a product for sale.

[0029] Beneficial effects:

[0030] (1) This invention creatively adopts a composite layered structure of "base adhesion layer + core repair layer". The cationic fiber polymer (polyquaternium-10) in the base adhesion layer can specifically target the negatively charged damaged areas on the hair surface through strong electrostatic adsorption, providing immediate and firm initial adhesion, solving the problems of easy slippage and poor adhesion of traditional products. The core repair layer above, especially the nano / micro fiber membrane constructed by electrospinning technology, has a high specific surface area and a porous interconnected structure. This not only greatly increases the loading of active ingredients, but also enables the repair ingredients to act continuously and directionally on the hair through the capillary action and slow-release characteristics of the fiber network. In particular, it can guide low molecular weight keratin and hydrolyzed silk fibroin to penetrate into the damaged cuticle and internal cavities, achieving a perfect connection from rapid targeted adhesion to long-term precise action;

[0031] (2) The core repair layer of this invention constructs a multi-mechanism synergistic repair system. Low molecular weight wool keratin and hydrolyzed silk fibroin can directly replenish the protein matrix lost by the hair. Among them, the free sulfhydryl groups rich in keratin peptides can penetrate into the hair cortex and exchange with the broken disulfide bonds of damaged keratin, rebuilding the protein network from the inside; while the specially added cystine, as an exogenous disulfide bond donor, can further participate in and promote the reconstruction and reinforcement of disulfide bonds under thermal cross-linking and usage conditions, significantly enhancing hair toughness and fundamentally reducing hair breakage and split ends. At the same time, the co-formed hydrolyzed silk fibroin has good film-forming properties and biocompatibility, which can further fill surface defects and synergistically form a dense and flexible protective film with keratin. This multi-layered deep repair mechanism of "protein replenishment (keratin / silk fibroin) + penetration bonding (sulfhydryl exchange) + cross-linking enhancement (cystine)" achieves three-dimensional and fundamental repair of hair from the inside out;

[0032] (3) By precisely controlling the molecular weight and ratio of each layer of materials and employing advanced processes such as dialysis purification, electrospinning, and thermal crosslinking, this invention ensures the stability and superior performance of the final product. All major components (wool keratin and hydrolyzed silk fibroin) are derived from natural biomaterials and have excellent biocompatibility. The preparation process relies on physical interactions and thermally induced crosslinking between polymer chains, avoiding the use of harmful chemical crosslinking agents and ensuring that the product is gentle and non-irritating to the scalp and hair. Electrospinning technology gives the core repair layer a light, breathable, and non-greasy feel, while high-temperature thermal crosslinking treatment stabilizes the composite membrane structure. The final product exists in the form of a dry film, which can be directly applied to wet hair for use. The active ingredients work intensively without heating, prolonged application, or rinsing. It is ready to use immediately after application, greatly improving the convenience, comfort, and efficiency of use.

[0033] (4) In designing the core repair layer formula, this invention fully considers the diverse needs of damaged hair. In addition to the basic protein repair system, it pays special attention to combating oxidative damage and preventing dryness and yellowing. For example, the keratin with high homocysteine ​​content derived from specific wool has antioxidant potential, and the compounded ingredients such as panthenol (vitamin B5) can provide strong antioxidant protection and neutralize free radicals; at the same time, the silane protectants in the formula (such as amino silicone oil) can form a glossy film on the hair surface, effectively reflecting ultraviolet rays and providing heat protection, synergistically delaying the yellowing process of hair caused by photo-oxidation. In addition, the composite film can form a light and long-lasting protective film on the hair after use, continuously resisting environmental damage. This enables the product to simultaneously achieve multiple care goals of deep repair, long-lasting nourishment, high-efficiency anti-oxidation and long-lasting physical protection;

[0034] (5) As a product that comes into direct contact with hair and scalp, safety is of paramount importance. This invention ensures safety from the source of raw materials: the main active ingredients, wool keratin and silk fibroin, are extracted from natural hair and silk, and are similar in structure to human keratin, exhibiting high biocompatibility and low risk of sensitization. In the manufacturing process, film formation and stabilization are achieved through gentle methods such as physical blending and thermal cross-linking, avoiding the use of irritating chemical cross-linking agents such as formaldehyde and glutaraldehyde throughout the entire process, thus eliminating harmful residues at the source. The final product is sterilized by ultraviolet light and individually packaged, further ensuring hygiene and safety before use. This comprehensive control over biocompatibility and safety makes the product suitable for a wide range of consumers, including sensitive individuals, meeting the current market's urgent demand for green, safe, gentle, and highly effective hair care products. Detailed Implementation

[0035] The present invention will be described in detail below with reference to embodiments. However, it should be understood that the following embodiments are merely illustrative examples of implementation of the present invention and are not intended to limit the scope of the present invention.

[0036] The CAS number of the amino silicone oil used in the following embodiments of the present invention is 63148-62-0.

[0037] The CAS number of the hydrolyzed silk fibroin used in the following embodiments of the present invention is 96690-41-4.

[0038] The CAS number of the cystine powder used in the following embodiments of the present invention is 56-89-3.

[0039] The CAS number of panthenol used in the following embodiments of the present invention is 81-13-0.

[0040] Example 1

[0041] A hair styling mask for hair care is prepared as follows:

[0042] S1. Add 3g of wool keratin (molecular weight of 20 kDa) and 1.5g of polyquaternium-10 to 100mL of Tris-HCl buffer at pH=8.5. After dialysis purification (the molecular weight cutoff of the dialysis membrane is 10 kDa), a uniform substrate adhesion solution is obtained.

[0043] S2. Dissolve 8g of wool keratin (molecular weight 20 kDa) and 5g of hydrolyzed silk fibroin (molecular weight 5 kDa) in 100mL of HFIP and stir magnetically overnight. Then, add 0.5g of cystine powder, 1g of panthenol, and 1.5g of amino silicone oil to the raw material system and continue stirring until homogeneous to obtain the core repair solution;

[0044] S3. First, 15 mL of substrate adhesion solution was poured into a mold and dried at 50°C to form a 40 μm thick substrate adhesion layer. Then, using electrospinning technology (voltage 18 kV, feed rate 1.0 mL / h), the core repair solution was electrospinned onto the surface of the substrate adhesion layer to form an 80 μm thick core repair layer, resulting in a composite film.

[0045] S4. Bake the composite film at 105℃ for 30 minutes, cool it, remove the composite film, cut it into 10cm×2cm hair tie film, sterilize it with ultraviolet light, and then seal it with aluminum foil.

[0046] Example 2

[0047] A hair styling mask for hair care is prepared as follows:

[0048] S1. Keratin and polyquaternium-10 are added to an aqueous solution at a mass ratio of 2:1 and stirred until homogeneous to obtain a substrate adhesion solution with a mass concentration of 4%.

[0049] S2. Add 12g of keratin and 8g of hydrolyzed silk fibroin to 100mL of anhydrous ethanol and water in a volume ratio of 1:9 to form an ethanol-water solution (acetic acid is also added to the ethanol-water solution, with a mass percentage of 0.5%). Then, add 2g of panthenol, 1g of vitamin E, and 2g of polydimethylsiloxane alcohol to the raw material system, and after homogenization and dispersion, obtain the core repair solution;

[0050] S3. Using the sequential casting method: First, the substrate adhesion liquid is poured to form a 40μm thick substrate adhesion layer. After the substrate adhesion layer is semi-dry, the core repair liquid is poured on the surface of the substrate adhesion layer to form an 80μm thick core repair layer. The core repair layer is then dried and formed at 45℃ and 60% humidity to obtain the composite membrane.

[0051] S4. The composite film is fumigated at 60°C for 6 hours with a 0.5% genipin aqueous solution. After fumigation, the composite film is rinsed three times in deionized water. After absorbing the surface moisture of the composite film with filter paper, it is placed in a 37°C oven to dry overnight. The composite film is then removed, cut into 10cm×2cm hair tie film, sterilized with ultraviolet light, and sealed in aluminum foil packaging.

[0052] Example 3

[0053] A hair styling mask for hair care is prepared as follows:

[0054] S1. Same as step S1 in Example 1;

[0055] S2. Add 10g of keratin and 6g of hydrolyzed silk fibroin to 100mL of HFIP. Then, add 1.5g of cystine, 0.5g of light stabilizer (methylenebis-benzotriazolyltetramethylbutylphenol, CAS: 155633-54-8), and 1g of natural plant essential oil (Argan oil, brand: Hairui, purity 99%) to the raw material system, stir well, and obtain the core repair solution;

[0056] S3. Same as step S3 in Example 1;

[0057] S4. Cut the composite film into 10cm×2cm hair tie film, sterilize with ultraviolet light, and then seal and package with aluminum foil.

[0058] Comparative Example 1

[0059] A hair styling mask for hair care is prepared as follows:

[0060] S1. Preparation of mixed solution: Add 3g wool keratin (20 kDa), 1.5g polyquaternium-10, 8g keratin, 5g hydrolyzed silk fibroin (5 kDa), 0.5g cystine powder, 1g panthenol, and 1.5g amino silicone oil to a mixed solution formed by 100mL of Tris-HCl buffer (pH=8.5) and 100mL of HFIP at a volume ratio of 1:1. Stir vigorously and homogenize overnight to obtain electrospinning solution;

[0061] S2. Using electrospinning technology (voltage 20 kV, receiving distance 15 cm, feed speed 1.2 mL / h), the above electrospinning solution was directly spun onto the receiving plate to obtain a fiber membrane with a total thickness of 120 μm.

[0062] S3. Bake the obtained fiber membrane at 105℃ for 30 minutes, cool it, take out the composite membrane, cut it into 10cm×2cm hair tie film, sterilize it with ultraviolet light, and then seal it with aluminum foil.

[0063] The purpose of Comparative Example 1 is to demonstrate that the layered design of the hair strand patch obtained in Example 1 of this invention, characterized by "dense adhesion at the bottom and porous repair at the top," is broken. The cationic components interact with silicone oil and other substances, affecting the electrostatic adsorption of the hair strand patch onto the hair. Simultaneously, the release of active ingredients is controlled by a single film layer, resulting in poor sustained-release effects, weak adhesion, premature loss of repair components, and uneven action.

[0064] Comparative Example 2

[0065] A hair styling mask for hair care is prepared as follows:

[0066] S1. Preparation of the mixed solution: Add 3g of wool keratin (20 kDa), 1.5g of polyquaternium-10, 8g of keratin, 5g of hydrolyzed silk fibroin (5 kDa), 0.5g of cystine powder, 1g of panthenol, and 1.5g of amino silicone oil to a mixed solution formed by mixing 100mL of Tris-HCl buffer (pH=8.5) and 100mL of HFIP at a volume ratio of 1:1. Stir vigorously and homogenize overnight to obtain the mixed solution.

[0067] S2. The above mixture is cast into a film using a casting method to obtain a fiber membrane with a total thickness of 120 μm;

[0068] S3. Bake the obtained fiber membrane at 105℃ for 30 minutes, cool it, take out the composite membrane, cut it into 10cm×2cm hair tie film, sterilize it with ultraviolet light, and then seal it with aluminum foil.

[0069] Comparative Example 3 is the same as Example 1, except that polyquaternium-10 was not added in step S1 of Comparative Example 3. To demonstrate that the substrate adhesion layer lacks cationic properties, it cannot generate a strong electrostatic adsorption effect on the negatively charged damaged hair surface after shampooing, resulting in a significant decrease in the initial adhesion of the film on wet hair. During use (such as during slight activity or massage), it is prone to displacement or detachment, affecting user experience and the effective delivery of repairing ingredients.

[0070] Comparative Example 4 is the same as Example 1, except that the polyquaternium-10 in step S1 of Example 1 is replaced with amino silicone oil. Amino silicone oil has certain cationic or film-forming properties, but its molecular structure, charge density, and interaction with keratin differ from polyquaternium-10. To demonstrate that the hair strand film obtained in Example 1 of this invention has better mechanical properties, its adhesion to wet hair mainly depends on the physical spreading of the silicone oil rather than strong electrostatic action, resulting in more durable adhesion.

[0071] The method of using the hair strand mask for hair care obtained by this invention is as follows:

[0072] 1. Preparation stage

[0073] Suitable for: Especially suitable for damaged hair that has been permed or dyed, sun-damaged, dry, frizzy, and prone to breakage and split ends. Healthy hair can also use it to enhance shine and provide protection.

[0074] Hair condition: Recommended for use after shampooing. Gently towel dry hair until it is damp but not dripping wet. At this point, the hair cuticle is slightly open, which is more conducive to the penetration of active ingredients.

[0075] 2. Film removal and application

[0076] Take out a hair tie film (10cm x 2cm) from the sealed packaging.

[0077] Apply the base layer of the hair strand mask directly to the target hair strand. Utilizing the adhesive properties of the mask itself and the surface tension of the moist hair, gently smooth it along the hair strand with your fingers to ensure that the mask adheres tightly and smoothly to the hair without air bubbles or lifting.

[0078] 3. Action and Penetration (Crucial 5 minutes)

[0079] After application, no additional heating or complicated procedures are required. Allow to stand at room temperature for 5 minutes.

[0080] Mechanism of action: Within these 5 minutes:

[0081] Initial stage (0-2 minutes): The humid environment and the moisture on the hair surface activate the base adhesion layer. Its cationic properties quickly establish a strong electrostatic adsorption with the negatively charged hair, ensuring the film is fixed.

[0082] Core Phase (2-5 minutes): Moisture continuously penetrates the three-dimensional fiber network of the core repair layer, initiating the targeted and sustained release of active ingredients. Low molecular weight wool keratin and hydrolyzed silk fibroin begin to penetrate into the cuticle gaps and cortex; simultaneously, active ingredients such as cystine and panthenol begin to work on the hair surface and superficial layers.

[0083] Users can perform other personal care procedures during this period without restriction.

[0084] 4. Removal and subsequent processing

[0085] No rinsing is required after 5 minutes.

[0086] Removal method: Hold one end of the film with your fingers and gently peel it off along the direction of hair growth. Due to the film's complete mechanical properties, it can be easily removed in one piece, leaving no residue and no stickiness.

[0087] Next steps: After removing the mask, you can immediately proceed with styling (such as blow-drying and combing).

[0088] Performance testing

[0089] Performance tests were conducted on the hair strand patches obtained in the embodiments and comparative examples of the present invention. Seventy subjects with hair damage from perming and dyeing were selected and divided into 7 groups for 3 weeks of the same hair care test. Each group corresponded to the hair strand patches obtained in Examples 1-3 and Comparative Examples 1-4, respectively. The test results for each group are shown in Table 1.

[0090] The instructions for using hair tie film are as follows:

[0091] 1. Preparation stage

[0092] Use a towel to gently pat your hair dry until it is damp but not dripping wet.

[0093] 2. Film removal and application

[0094] Remove the hair tie film (10cm x 2cm) from the sealed packaging.

[0095] The base layer of the hair strand adhesive film is directly applied to the target hair strand of the subject whose hair has been permed or dyed. Utilizing the adhesiveness of the film itself and the surface tension of the moist hair, the hair strand is gently smoothed with fingers to ensure that the film adheres tightly and smoothly to the hair without air bubbles or lifting.

[0096] 3. Function and Osmosis

[0097] After application, no additional heating or complicated procedures are required. Allow to stand at room temperature for 5 minutes.

[0098] 4. Removal and subsequent processing

[0099] No rinsing is required after 5 minutes.

[0100] Removal method: Hold one end of the film with your fingers and gently peel it off along the direction of hair growth. Due to the film's excellent mechanical properties, it can be easily removed in one piece, leaving no residue or stickiness. Follow-up steps: After removing the film, blow-dry and comb your hair.

[0101] Table 1

[0102] Test Items Increase in fracture strength (%) Increase in gloss (%) Hair cuticle damage repair rate (%) Overall performance evaluation Example 1 58-65 50-60 90-95 Overall optimal performance. The complete layered design and electrospinning process achieve strong adhesion, deep penetration, and slow release. It combines excellent structural repair (strength), surface smoothness (gloss), and cuticle coverage repair effects. Example 2 35-42 40-45 75-85 Excellent, with a focus on daily protection. The membrane structure formed by the sequential casting method remains effective, and the nourishing and anti-UV components (vitamin E, silane) enhance gloss and protection, but the deep structural repair strength is slightly lower than that of Example 1. Example 3 30-40 30-40 70-75 Excellent for severe damage. High concentration of cystine and strengthening repair ingredients significantly improve fracture strength; added protective ingredients (light stabilizer) protect newly formed structures while repairing. Comparative Example 1 15-22 20-30 40-55 The effectiveness was significantly reduced. The single structure led to functional disorder: poor adhesion affected the action of the ingredients, the release of active substances was disordered, and an effective repair layer could not be formed. All indicators were inferior to those of the layered implementation. Comparative Example 2 10-18 15-25 20-40 The effect is poor. The casting process creates a dense, non-porous film, which completely "locks" the active ingredients inside, preventing them from being effectively released and penetrated into the hair. The film itself also struggles to adhere tightly to the hair strands. Comparative Example 3 8-15 15-25 30-45 The worst effect. Due to the lack of cationic electrostatic adsorption, the film does not make firm contact with the hair, and most of the active ingredients are lost before they can be applied, failing to achieve effective repair and coverage. Comparative Example 4 12-20 25-35 35-50 The results were unsatisfactory. Amino silicone oil cannot replace the film-forming and adsorption functions of cationic polymers, resulting in unstable substrate properties and low overall repair efficiency.

[0103] The advantages of this invention compared to traditional hair masks are shown in Table 2:

[0104] Table 2

[0105] Feature Comparison Keratin composite fiber membrane obtained in Example 1 of this invention Traditional hair masks / conditioners Adhesion mechanism Cationic substrate + biomimetic fiber mesh, strong electrostatic adsorption and physical anchoring It mainly relies on cationic conditioners, has weak adsorption capacity, and is easy to rinse. Repair depth Deep repair: Small molecule peptides can penetrate into the cortex and rebuild disulfide bonds. Surface repair: Large molecules mainly cover the hair surface and cannot penetrate deeply. Active ingredient delivery Targeted sustained release: Active ingredients are encapsulated in the fibers and released into the hair strands during use. Immediate contact: The ingredients are dispersed in the matrix, resulting in low efficiency in contact with the hair. Repair efficacy Fundamental enhancement: Filling protein voids and rebuilding disulfide bonds, fundamentally reducing hair breakage and splitting. Temporary smoothness: This mainly achieves immediate smoothness through silicone oils, fatty alcohols, etc., but it only treats the symptoms and not the root cause. Protective function Multiple synergistic protection: Antioxidant (Vitamin B5 / E) + UV reflection (silane) + thermal protection Single-function: Usually focuses on one aspect of care, with weak protective function. Ease of use Highly efficient and convenient: Apply and care immediately, no need for prolonged application or heating, and no greasy feeling. The process is cumbersome: some products require heating or sitting for 10-30 minutes, which may result in uneven distribution and greasiness.

[0106] The special effects of the hair tie patches obtained in Examples 1-3 of this invention are shown in Table 3:

[0107] Table 3

[0108] Test comparison Example 1 Example 2 Example 3 Core Repair Layer Formula Keratin: 8g; Hydrolyzed silk fibroin: 5g; Cystine: 0.5g; Panthenol: 1g; Amino silicone oil: 1.5g Keratin: 12g; Hydrolyzed silk fibroin: 8g; Panthenol: 2g; Vitamin E: 1g; Polydimethylsiloxane alcohol: 2g Keratin: 10g; Hydrolyzed silk fibroin: 6g; Cystine: 1.5g; Light stabilizer: 0.5g; Plant essential oil: 1g Preparation process Base casting + electrospinning of repair layer Sequential pouring Base casting + electrospinning of repair layer Crosslinking method thermal crosslinking Genipin (chemical crosslinking) Physical crosslinking Product Features Strong adhesion, combining deep repair and surface protection Ultimate smoothness, with a focus on anti-oxidation and UV protection. High-strength disulfide bond reconstruction, targeting severely damaged and brittle hair. Suitable for target hair type Damage from perming and dyeing, roughness, and lack of elasticity Daily care, protection against ultraviolet radiation and heat damage Extremely fragile, split ends, and easily broken hair

[0109] Based on the above-described preferred embodiments of the present invention, and through the foregoing description, those skilled in the art can make various changes and modifications without departing from the inventive concept. The technical scope of this invention is not limited to the contents of the specification, but must be determined according to the scope of the claims.

Claims

1. A keratin composite active fiber membrane for hair care, characterized in that, It has a layered structure, comprising at least one base attachment layer and at least one core repair layer from bottom to top, with adjacent base attachment layers and core repair layers undergoing interfacial composite through physical interaction and / or chemical bonding. The substrate adhesion layer is formed by casting; the core repair layer is formed by casting or electrospinning. The raw material used for the substrate adhesion layer is a homogeneous mixture of wool keratin and cationic fiber polymers in an alkaline Tris-HCl buffer or water. The raw materials used in the core repair layer are a uniform dispersion of wool keratin, hydrolyzed silk fibroin, and active ingredients in an ethanol aqueous solution or HFIP containing acetic acid. The molecular weight of hydrolyzed silk fibroin is <10 kDa, and the molecular weight of wool keratin is 5 kDa~40 kDa.

2. The keratin composite active fiber membrane for hair care according to claim 1, characterized in that, The molecular weight of wool keratin is 10~30 kDa.

3. The keratin composite active fiber membrane for hair care according to claim 1, characterized in that, The pH of the alkaline Tris-HCl buffer is 8.

5.

4. The keratin composite active fiber membrane for hair care according to claim 1, characterized in that, The mass ratio of wool keratin to cationic fiber polymer in the raw materials used for the base adhesion layer is 1:1 to 3:

1.

5. A keratin composite active fiber membrane for hair care according to claim 1, characterized in that, The mass ratio of wool keratin to hydrolyzed silk fibroin and active ingredients in the raw materials used in the core repair layer is (8-20):(5-12):(1-5).

6. A keratin composite active fiber membrane for hair care according to claim 1, characterized in that, The thickness of the substrate adhesion layer is 15-60 μm.

7. A keratin composite active fiber membrane for hair care according to claim 1, characterized in that, The thickness of the core repair layer is 40-150μm.

8. A keratin composite active fiber membrane for hair care according to claim 1, characterized in that, The active ingredients include one or more of the following: cystine, panthenol, amino silicone oil, vitamin E, polydimethylsiloxane alcohol, light stabilizers, and natural plant essential oils.

9. A keratin composite active fiber membrane for hair care according to any one of claims 1-8, characterized in that, The preparation method includes the following steps: (1) Add wool keratin and cationic fiber polymer to alkaline Tris-HCl buffer according to the formula amount, and after dialysis purification, a uniform substrate adhesion solution is obtained. (2) Dissolve keratin and hydrolyzed silk fibroin in HFIP or an ethanol aqueous solution containing acetic acid according to the formula amount, stir evenly, add active ingredients, and continue stirring until uniform to obtain a uniform core repair solution. (3) The base adhesion liquid is poured into the mold and dried to form the base adhesion layer. Then, the core repair liquid is formed on the surface of the base adhesion layer by pouring or electrospinning to form the core repair layer, thus obtaining the keratin composite active fiber membrane. After ultraviolet sterilization, it is packaged into a product for sale using aluminum foil film.

10. A keratin composite active fiber membrane for hair care according to claim 9, characterized in that, Step (3) is performed as follows: The base adhesion liquid is poured into a mold and dried to form a base adhesion layer. Then, the core repair liquid is formed on the surface of the base adhesion layer by pouring or electrospinning to form a core repair layer, resulting in a composite film. The composite film is then subjected to high-temperature thermal cross-linking, cooled, and cut into keratin composite active fiber films of the required size. After ultraviolet sterilization, it is packaged in aluminum foil film as a product for sale.