Thrombectomy assembly, system, and method

Abstract

The application provides a thrombus removal assembly, system and method, a transmission pipe movably sleeved outside an inner core pipe, a suction pipe movably sleeved outside the transmission pipe, a pipe cavity of the suction pipe is configured to form a suction channel, a pull plug body has a filter plug cavity and a cavity opening communicating with the filter plug cavity, a proximal end of the pull plug body is connected with the inner core pipe, a distal end of the pull plug body is connected with the suction pipe, a broken plug body is arranged at a proximal end of the transmission pipe and used for entering and exiting the filter plug cavity of the pull plug body through the cavity opening of the pull plug body. The filter plug cavity of the pull plug body captures a thrombus, the broken plug body enters the filter plug cavity of the pull plug body, the broken plug body is controlled to mechanically move through the transmission pipe, the thrombus in the filter plug cavity is crushed through the mechanical movement, a negative pressure of suction is generated in the suction channel, the crushed thrombus is sucked along the suction channel, and based on the integrated suction plug function, the pull plug function and the broken plug function, the thrombus is finally removed, and the thrombus removal effect is improved.

Description

Technical Field

[0001] This application relates to the field of medical device technology, and in particular to thrombus removal components, systems, and methods. Background Technology

[0002] Deep venous thrombosis (DVT) is a disease caused by abnormal blood clotting in the deep veins of the lower extremities. DVT easily leads to increased venous pressure, obstructed blood return, and symptoms such as lower extremity swelling, pain, and dysfunction. There is also a risk of thrombus detachment, which can travel with the bloodstream to the pulmonary artery, potentially causing pulmonary embolism (PE). If DVT is not effectively treated in the acute phase, it can lead to thrombus organization, venous obstruction, loss of valvular function, venous reflux, and venous hypertension, resulting in post-thrombosis syndrome (PTS), which can endanger limb survival and threaten life.

[0003] In the above situations, oral or injectable aspirin, heparin, or warfarin can effectively dissolve venous thrombi. However, in patients with a history of bleeding disorders, hemorrhagic diabetes, hemorrhagic stroke, neurosurgical procedures, severe trauma, hemoplegia, pelvic and lower limb fractures caused by intracranial hemorrhage, or anticoagulant disorders, severe systemic bleeding may occur, endangering the patient's life. Catheter-directed thrombolysis (CDT) can deliver thrombolytic drugs (such as urokinase) to the thrombus site, effectively reducing the thrombus burden. However, CDT treatment for deep vein thrombosis (DVT) has the problem of a long thrombolysis time (average 53.4 hours), which prolongs hospital stay and is not conducive to quickly restoring blood flow. In addition, the bleeding risk of thrombolytic drugs makes it unsuitable for patients with high bleeding risk (such as severe hypertension) and unsuitable for patients in labor or pregnancy.

[0004] Percutaneous mechanical thrombectomy (PMT) devices are used to remove acute and subacute thrombi from blood vessels, including methods such as aspiration, thrombectomy, and thrombectomy. Aspiration thrombectomy is prone to failure to remove subacute or large thrombi, or blockage of the aspiration tube. Thrombectomy often requires repeated insertion and withdrawal from the vessel, causing additional pain to the patient and increasing surgical time, making it inconvenient to perform. Thrombolysis devices mostly use mechanical rotation or hydrodissection. Mechanical rotation can easily damage the vessel wall, posing a safety risk, while hydrodissection is only effective for free thrombi and is less effective for thrombi adhering to the vessel wall.

[0005] Therefore, the existing mechanical thrombus removal components are not very effective and have risks such as incomplete thrombus removal, long operation time, and easy damage to the blood vessel wall. Summary of the Invention

[0006] Therefore, it is necessary to provide a thrombus removal component, system, and method to address at least one of the aforementioned technical problems.

[0007] This application provides a thrombus removal assembly, the thrombus removal assembly comprising:

[0008] Inner core tube;

[0009] A transmission tube, which is movably sleeved outside the inner core tube;

[0010] A suction tube, which is movably sleeved outside the transmission tube, has its inner cavity configured to form a suction channel.

[0011] A plug body, the plug body having a filter plug cavity and a cavity opening communicating with the filter plug cavity, the proximal end of the plug body being connected to the inner core tube, and the distal end of the plug body being connected to the suction tube;

[0012] A puncture-breaking body is disposed at the proximal end of the transmission tube and is used to enter and exit the filter puncture cavity of the pull puncture body through the cavity port of the pull puncture body.

[0013] In one embodiment, the tube layer gap between the inner wall of the suction tube and the outer wall of the transmission tube is configured to form the suction channel; and / or,

[0014] The plug body is configured to allow non-target objects to flow through the plug cavity and retain target objects within the plug cavity; and / or,

[0015] The pull-bolt body has a deformation capability for switching between a contracted state and an expanded state; the relative movement between the inner core tube and the suction tube is configured to change the deformation state of the pull-bolt body; and / or

[0016] The cavity opening of the thimble is located at the distal end of the thimble; the inner cavity of the suction tube communicates with the cavity opening of the thimble; the movement of the transmission tube relative to the suction tube is configured to control the movement of the broken thimble fragments through the cavity opening of the thimble and out of the filter thimble cavity; and / or,

[0017] The suction tube is connected to the distal end of the pull-bolt body via a connector; and / or

[0018] The puncture body has a deformation capability for switching between a contracted state and an expanded state, and the movement of the transmission tube relative to the suction tube is at least configured to change the deformation state of the puncture body.

[0019] In one embodiment, the non-target body is blood, and the target body is a thrombus; and / or,

[0020] The bolt body is a filter screen structure; and / or,

[0021] The surface of the bolt body is provided with a filter structure; and / or

[0022] The proximal end of the thimble is closed, and the distal end of the thimble is open to form the cavity. The size of the thimble gradually increases from the proximal end to the distal end; and / or,

[0023] The suction tube has a plurality of first connection positions distributed circumferentially, and the distal end of the pull plug has a plurality of second connection positions distributed thereon. One end of a plurality of connectors is connected to a plurality of the first connection positions of the suction tube, and the other end of a plurality of connectors is connected to a plurality of the second connection positions of the pull plug; and / or,

[0024] The connector is integrally formed with the bolt body.

[0025] In one embodiment, the thrombus fragment includes:

[0026] A break-off element, wherein the number of break-off elements is configured to be at least one, the break-off element having deformability, the break-off element being connected to the transmission tube, and the break-off element being configured to be in force-contact with the suction tube, and to switch between a contracted state and an expanded state through interaction forces relative to the suction tube.

[0027] In one embodiment, at least one end of the break-fitting element is connected to the transmission tube, and the other end is in a suspended state not connected to the transmission tube; and / or,

[0028] Several of the aforementioned break-locking elements are arranged along the circumferential direction of the transmission tube on the outer wall of the transmission tube.

[0029] In one embodiment, at least one of the debriding elements is a linear structural element; and / or,

[0030] At least one of the aforementioned break-off elements is a linear element or a curved element; and / or,

[0031] At least one of the bolt-breaking elements is staggered relative to the other bolt-breaking elements in the axial direction of the transmission tube.

[0032] In one embodiment, a plurality of the bolt-breaking elements are linear elements arranged radially along the transmission tube; or,

[0033] Some of the aforementioned break-bolt elements are curved elements, bending from the inside to the outside along the radial direction of the transmission tube.

[0034] In one embodiment, the thrombus removal component includes:

[0035] An outer sheath is movably sleeved outside the suction tube, and the inner cavity of the outer sheath is configured to receive the pull plug.

[0036] This application provides a thrombus removal system, which includes the thrombus removal component.

[0037] This application provides a thrombus removal method based on the thrombus removal component or the thrombus removal system, the thrombus removal method comprising the following steps:

[0038] Control the relative movement of the inner core tube and the suction tube, adjust the deformation state of the pull plug body, and capture the target body into the filter plug cavity of the pull plug body;

[0039] Controlling the relative movement of the transmission tube and the suction tube, the target object inside the filter plug cavity is crushed by the filter plug fragments that enter the filter plug cavity;

[0040] The pulverized target object is extracted through the suction channel.

[0041] In the aforementioned thrombus removal components, systems, and methods, the user can capture the thrombus using the filter cavity of the thrombus puller and allow blood and other liquids to flow through the filter cavity. The fragmented thrombus enters the filter cavity of the puller and is mechanically moved by the transmission tube. The mechanical movement breaks up the thrombus in the filter cavity, generating a negative pressure in the suction channel. The fragmented thrombus is then suctioned along the suction channel. Based on the integrated suction, puller, and fragmentation functions, the thrombus is ultimately removed, improving the thrombus removal effect. Attached Figure Description

[0042] Figure 1 This is a schematic diagram of the structure of a thrombus removal component provided in one embodiment of this application.

[0043] Figure 2 For example Figure 1 The diagram shows the usage status of the thrombus removal component.

[0044] Figure 3 This is a schematic diagram of the structure of a puncture-breaking element provided in one embodiment of this application.

[0045] Figure 4 For example Figure 3 The diagram shows a three-dimensional structure of the puncture-breaking element.

[0046] Figure 5 This is a schematic diagram of the structure of a puncture-breaking element provided in another embodiment of this application.

[0047] Figure 6 This is a schematic diagram of the structure of a break-off element provided in another embodiment of this application.

[0048] Figure 7 This is a fully unfolded schematic diagram of a puncture-breaking element provided in one embodiment of this application.

[0049] Figure 8 This is a partially unfolded schematic diagram of a puncture element provided in one embodiment of this application.

[0050] Icon labels:

[0051] 100. Target blood vessel;

[0052] 1000, Inner core tube; 2000, Transmission tube; 3000, Suction tube; 4000, Outer sheath tube; 5000, Bolt puller body; 6000, Bolt fragment body;

[0053] 1100, First connecting component; 1200, Guiding component; 2100, Second connecting component; 3100, Third connecting component; 4100, Fourth connecting component;

[0054] 5100, Filter plug cavity; 5200, Cavity opening; 5300, Connecting piece;

[0055] 6100, puncture-resistant components. Detailed Implementation

[0056] To make the above-mentioned objectives, features, and advantages of this application more apparent and understandable, the specific embodiments of this application are described in detail below with reference to the accompanying drawings. Many specific details are set forth in the following description to provide a thorough understanding of this application. However, this application can be implemented in many other ways different from those described herein, and those skilled in the art can make similar modifications without departing from the spirit of this application. Therefore, this application is not limited to the specific embodiments disclosed below.

[0057] In the description of this application, it should be understood that if terms such as "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", "axial", "radial", "circumferential" appear, these terms indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings, and are only for the convenience of describing this application and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this application.

[0058] Furthermore, where the terms "first" and "second" appear, these terms are for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of technical features indicated. Thus, a feature defined with "first" or "second" may explicitly or implicitly include at least one of that feature. In the description of this application, where the term "multiple" appears, "multiple" means at least two, such as two, three, etc., unless otherwise explicitly specified.

[0059] In this application, unless otherwise expressly specified and limited, the terms "installation," "connection," "joining," and "fixing," etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components, unless otherwise expressly limited. Those skilled in the art can understand the specific meaning of the above terms in this application based on the specific circumstances.

[0060] In this application, unless otherwise expressly specified and limited, the use of descriptions such as "above" or "below" the second feature indicates that the first and second features are in direct contact or indirect contact via an intermediate medium. Furthermore, "above," "on top of," and "over" the second feature can mean that the first feature is directly above or diagonally above the second feature, or simply that the first feature is at a higher horizontal level than the second feature. Similarly, "below," "below," and "under" the second feature can mean that the first feature is directly below or diagonally below the second feature, or simply that the first feature is at a lower horizontal level than the second feature.

[0061] It should be noted that if an element is referred to as being "fixed to" or "set on" another element, it can be directly on the other element or there may be an intervening element. If an element is considered to be "connected to" another element, it can be directly connected to the other element or there may be an intervening element. If so, the terms "vertical," "horizontal," "upper," "lower," "left," "right," and similar expressions used in this application are for illustrative purposes only and do not represent the only possible implementation.

[0062] To more clearly describe the above-described thrombus removal components, systems, and methods, the term "proximal end" is defined herein as the end closer to the patient during the surgical procedure, i.e., the end furthest from the operator, and "distal end" is defined as the end furthest from the patient during the surgical procedure, i.e., the end closer to the operator. Unless otherwise defined, all technical and scientific terms used in this application have the same meaning as commonly understood by one of ordinary skill in the art to which this application belongs. The terminology used in this application's specification is for the purpose of describing particular embodiments only and is not intended to be limiting of the application.

[0063] See Figure 1 and Figure 2 As shown, this application provides a thrombus removal system, which includes a thrombus removal assembly and other auxiliary components for controlling the thrombus removal assembly. The thrombus removal assembly includes an inner core tube 1000, a transmission tube 2000, and a suction tube 3000. The transmission tube 2000 is movably sleeved outside the inner core tube 1000, and the suction tube 3000 is movably sleeved outside the transmission tube 2000. Based on the interlocking assembly of the inner core tube 1000, transmission tube 2000, and suction tube 3000, the thrombus removal assembly can thus achieve thrombus suction, thrombus pulling, and thrombus fragmentation functions, realizing deep thrombus removal in a three-in-one manner. Other auxiliary components may include a first connecting component 1100, a guiding component 1200, a second connecting component 2100, a third connecting component 3100, a fourth connecting component 4100, etc., and are not limited thereto.

[0064] For information on the suction function, please refer to [link / reference]. Figure 1 and Figure 2 As shown, the inner cavity of the suction tube 3000 is configured to form a suction channel, which is used to aspirate the thrombus. In one embodiment, the tube layer gap between the inner wall of the suction tube 3000 and the outer wall of the transmission tube 2000 is configured to form a suction channel. Alternatively, those skilled in the art may also limit the tube layer gap between the inner wall of the transmission tube 2000 and the outer wall of the inner core tube 1000 to form a suction channel or to be part of a suction channel, as long as it satisfies the requirement of safely aspirating the thrombus. No limitation is made here.

[0065] Regarding the thrombus removal and fragmentation functions, the thrombus removal assembly also includes a thrombus puller 5000 and a thrombus fragmenter 6000. The thrombus puller 5000 has a thrombus-filtering cavity 5100 and a cavity opening 5200 communicating with the thrombus-filtering cavity 5100. The proximal end of the thrombus puller 5000 is connected to the inner core tube 1000, and the distal end is connected to the aspiration tube 3000. The non-target body is defined as blood, and the target body as a thrombus. The thrombus puller 5000 is configured to allow non-target bodies to flow through the thrombus-filtering cavity 5100 while retaining the target body within it. Therefore, the thrombus can enter the thrombus-filtering cavity 5100 through the cavity opening 5200 for capture. For example, in one embodiment, the thrombus-filtering cavity 5100 is used to accommodate the thrombus in the target blood vessel 100. A mesh, perforated, or similar structural design allows for smooth blood flow, but the thrombus needs to be captured within the thrombus-filtering cavity 5100. For example, the bolt body 5000 is made of woven metal wire with self-expanding function, or is made of metal tubing by laser engraving, without limitation.

[0066] The aforementioned pull-bolt body 5000, designed with a mesh structure for separating target and non-target objects, can be sized according to actual needs. For example, the pull-bolt body 5000 can have a denser or sparser mesh structure. A filter structure, such as a membrane or cover structure, can also be installed on the surface of the pull-bolt body 5000. The filter structure is configured with a mesh density different from that of the pull-bolt body 5000. Therefore, when the filter structure covers the surface of the pull-bolt body 5000, the superposition of the mesh structures on the pull-bolt body 5000 and the filter structure allows for real-time adjustment of the pull-bolt body 5000's filtration capacity, enabling the separation of target and non-target objects for different situations and broadening its application scenarios.

[0067] The thrombus fragment 6000 is positioned proximal to the transmission tube 2000, such as at the proximal end of the transmission tube 2000 or on the inner or outer wall of the tube near the proximal end. Based on the connection between the transmission tube 2000 and the thrombus fragment 6000, the movement of the transmission tube 2000 can control the movement of the thrombus fragment 6000, including but not limited to controlling the displacement and rotation of the thrombus fragment 6000. Thus, the transmission tube 2000 can control the thrombus fragment 6000 to enter and exit the thrombus filter cavity 5100 of the thrombus puller 5000 through the cavity opening 5200. Then, the transmission tube 2000 drives the movement of the thrombus fragment 6000, utilizing the mechanical force generated by the movement of the thrombus fragment 6000 to fragment and capture the thrombus in the thrombus filter cavity 5100.

[0068] Therefore, in the aforementioned thrombus removal process, the user can capture the thrombus using the filter cavity 5100 of the thrombus puller 5000, allowing blood and other fluids to flow through the filter cavity 5100. The thrombus fragment 6000 enters the filter cavity 5100 of the thrombus puller 5000, and the mechanical movement of the thrombus fragment 6000 is controlled by the transmission tube 2000, using mechanical movement to pulverize the thrombus in the filter cavity 5100. Then, a negative pressure can be generated in the thrombus suction channel, and the pulverized thrombus is suctioned along the suction channel. Based on the integrated thrombus suction, thrombus puller, and thrombus fragmentation functions, the final removal of the thrombus is achieved, improving the thrombus removal effect.

[0069] In one embodiment, the thrombectomy body 5000 may be configured to be deformable, allowing it to switch between a contracted state and an expanded state, whereby its volume is between contraction and expansion. In another embodiment, the thrombus removal assembly may further include an outer sheath 4000, which is movably fitted over the suction tube 3000. Therefore, when the thrombectomy body 5000 is in a contracted state, the inner cavity of the outer sheath 4000 is configured to receive the thrombectomy body 5000. Since the inner core tube 1000 and the suction tube 3000 are respectively connected to the proximal and distal ends of the thrombectomy body 5000, the relative movement between them can be configured to change the deformation state of the thrombectomy body 5000, enabling active control of its deformation state, including control over the opening size of the cavity 5200.

[0070] In one embodiment, the cavity 5200 of the thimble body 5000 is located at the distal end of the thimble body 5000, and the inner cavity of the suction tube 3000 communicates with the cavity 5200 of the thimble body 5000, such that the movement of the transmission tube 2000 relative to the suction tube 3000 is configured to control the thimble fragment 6000 to enter and exit the filter plug cavity 5100 of the thimble body 5000 through the cavity 5200 of the thimble body 5000. The cavity 5200 of the thimble body 5000 can be set at a suitable position in the thimble body 5000 according to the thimble requirements. For example, the proximal end of the thimble body 5000 is closed and the distal end of the thimble body 5000 is open, and the cavity 5200 is formed based on the opening of the distal end. Furthermore, the size of the thimble body 5000 gradually increases in the direction from the proximal end to the distal end. Especially when the thimble body 5000 is not in a contracted state, the degree of size increase in the direction from the proximal end to the distal end of the thimble body 5000 can be adjusted according to the deformation state.

[0071] Continue reading Figure 2As shown, a guide component 1200 can be provided at the proximal end of the inner core tube 1000, and the proximal end of the pull-bolt body 5000 is connected to the guide component 1200. Since the cavity opening 5200 at the distal end of the pull-bolt body 5000 changes its opening size according to the deformation state, the suction tube 3000 can be indirectly connected to the distal end of the pull-bolt body 5000 via the connector 5300. The connector 5300 can be a rod-shaped member, a wire-shaped member, or other structures that can adapt to the deformation of the pull-bolt body 5000, or the connector 5300 can be integrally formed with the pull-bolt body 5000 and formed together during the manufacturing of the pull-bolt body 5000. When the suction tube 3000 is connected to the pull plug body 5000 via the connector 5300, in one embodiment, the suction tube 3000 has a plurality of first connection positions distributed in the circumferential direction, the pull plug body 5000 has a plurality of second connection positions distributed at its distal end, one end of the plurality of connectors 5300 is connected to the plurality of first connection positions of the suction tube 3000, and the other end of the plurality of connectors 5300 is connected to the plurality of second connection positions of the pull plug body 5000.

[0072] In one embodiment, the bolus body 5000 may be configured to be deformable, enabling it to switch between a contracted state and an expanded state, whereby the volume of the bolus body 5000 is between these two states. Since the inner core tube 1000 and the suction tube 3000 are respectively connected to the proximal and distal ends of the bolus body 5000, the relative movement between the inner core tube 1000 and the suction tube 3000 can be configured to change the deformation state of the bolus body 5000, thereby achieving active control over the deformation state of the bolus body 5000, including control over the opening size of the cavity orifice 5200.

[0073] Therefore, the thrombectomy body 5000 is located inside the target blood vessel 100. The deformation state of the thrombectomy body 5000 can be adjusted according to the actual size of the target blood vessel 100, so that the size of the thrombectomy body 5000 is adaptively matched with the target blood vessel 100, including but not limited to the size of the cavity 5200 of the thrombectomy body 5000. This ensures that the thrombectomy body 5000 forms a tight fit with the blood vessel wall of the target blood vessel 100, and removes and gathers free or attached thrombi in one go, with a fast and efficient thrombectomy effect.

[0074] The thrombectomy unit 5000 and the thrombectomy unit 6000 work together. The thrombectomy unit 5000 not only prevents the fragmented thrombus from drifting, ensuring complete removal of the thrombus, but also protects the vessel wall, preventing damage from the thrombectomy unit 6000. The thrombectomy unit 6000 breaks up the gathered thrombus, improving suction efficiency and preventing blockage of the suction tube 3000 during thrombectomy. The thrombectomy unit 6000 is located proximal to the transmission tube 2000, which moves within the lumen of the suction tube 3000. Therefore, the mechanical movement of the thrombectomy unit is primarily located proximal to the opening of the suction tube 3000. This allows the mechanical movement of the thrombectomy unit 6000 to intercept larger, un-fragmented thrombi from entering the suction tube 3000, thus preventing blockage. Furthermore, the mechanical movement of the thrombus fragment 6000 is entirely achieved by the independent movement of the transmission tube 2000. During the thrombus aspiration process using the suction tube 3000, the transmission tube 2000 can move independently, thus allowing for multiple thrombus fragmentation operations as needed without affecting the aspiration and thrombus removal operations. This ensures that the thrombus is completely removed before the thrombus removal component is withdrawn from the patient's body.

[0075] In one embodiment, the thrombus fragment 6000 may also be configured to have deformability, allowing it to transition between a contracted state and an expanded state, whereby its volume is between contraction and expansion. Since the transmission tube 2000 connects to the thrombus fragment 6000 and is movable relative to the suction tube 3000, the movement of the transmission tube 2000 relative to the suction tube 3000 is at least configured to change the deformability of the thrombus 5000. For example, during the movement of the transmission tube 2000 relative to the suction tube 3000, the thrombus fragment 6000 may be forced into contact with the suction tube 3000. Therefore, the interaction force between the thrombus fragment 6000 and the suction tube 3000 can be used to control the transition between contraction and expansion states. Furthermore, those skilled in the art can also control the deformability of the thrombus fragment 6000 using other control methods, which are not limited here.

[0076] Continue reading Figure 3 As shown, in one embodiment, the bolt-breaking body 6000 includes bolt-breaking elements 6100, such as a metal bolt-breaking knife with a blade. The number of bolt-breaking elements 6100 is configured to be at least one, for example, there may be several bolt-breaking elements 6100, ranging from 3 to 10. In one embodiment, at least one end of the bolt-breaking element 6100 is connected to the transmission tube 2000, while the other end is in a suspended state not connected to the transmission tube 2000, thereby achieving connection with the transmission tube 2000.

[0077] In addition, the break-off element 6100 can be connected to the transmission tube 2000 through two or more connection points, as long as the break-off element 6100 can be controlled to switch between a contracted state and an expanded state based on the interaction force with the suction tube 3000. No limitation is made here. Furthermore, several break-off elements 6100 can be arranged along the circumference of the transmission tube 2000 on the outer wall of the tube, achieving a uniform distribution of the break-off elements 6100 relative to the transmission tube 2000.

[0078] Regarding the shape of the break-off element 6100, in one embodiment, at least one break-off element 6100 is a linear structural element, such as a straight element or a curved element. Figure 4 As shown, several bolt-breaking elements 6100 are curved elements, bending from the inside to the outside along the radial direction of the transmission tube 2000, such as... Figure 5 As shown, several bolt breaking elements 6100 are linear elements arranged radially along the transmission tube 2000.

[0079] Regarding the distribution of the bolt-breaking elements 6100 in the transmission tube 2000, several bolt-breaking elements 6100 may be circumferentially distributed along one or more circular trajectories on the outer wall of the transmission tube 2000, or as follows: Figure 6 As shown, one or more of the bolt breaking elements 6100 can be staggered relative to other bolt breaking elements 6100 in the axial direction of the transmission tube 2000, thus presenting a staggered distribution effect in both the circumferential and axial directions. Those skilled in the art can also realize the distribution of the bolt breaking elements 6100 according to the actual situation, which is not limited here.

[0080] Continue reading Figure 7 and Figure 8 As shown, all the break-up elements 6100 have deformation capabilities. Each break-up element 6100 is connected to the transmission tube 2000 and is configured to make force-contact with the suction tube 3000. This allows the break-up element 6100 to switch between a contracted and expanded deformation state through interaction forces relative to the suction tube 3000. For example... Figure 7 The diagram shows the fully deployed state of the thrombus breaking element 6100 extending from the suction tube 3000, with no interaction force between it and the suction tube 3000. Figure 8 This means that part of the puncture element 6100 enters the suction tube 3000 and is in a partially deployed state with an interaction force between it and the suction tube 3000.

[0081] This application provides a thrombus removal method based on a thrombus removal component or system. The thrombus removal method includes the following steps: controlling the relative movement of the inner core tube 1000 and the suction tube 3000, adjusting the deformation state of the thrombus puller 5000, and capturing the target body into the filter thrombus cavity 5100 of the thrombus puller 5000; controlling the relative movement of the transmission tube 2000 and the suction tube 3000, using the thrombus fragments 6000 entering the filter thrombus cavity 5100 to pulverize the target body within the filter thrombus cavity 5100; and suctioning out the pulverized target body through the suction channel.

[0082] Therefore, the user can capture the thrombus using the thrombus-filtering cavity 5100 of the thrombus-pulling body 5000, and allow blood and other liquids to flow through the thrombus-filtering cavity 5100. The thrombus fragmentation body 6000 enters the thrombus-filtering cavity 5100 of the thrombus-pulling body 5000, and the mechanical movement of the thrombus fragmentation body 6000 is controlled by the transmission tube 2000. The mechanical movement breaks up the thrombus in the thrombus-filtering cavity 5100, and a negative pressure can be generated in the thrombus-suction channel. The fragmented thrombus is then suctioned along the thrombus-suction channel. Based on the integrated thrombus-suction, thrombus-pulling and thrombus-fracturing functions, the final removal of the thrombus is achieved, improving the thrombus removal effect.

[0083] In one embodiment, after puncturing the target blood vessel 100, the thrombus removal system is implanted along the guidewire into the target location of the target blood vessel 100. Under X-ray guidance, the outer sheath 4000 is withdrawn, the thrombus puller 5000 is opened, and then the position of the suction tube 3000 in the target blood vessel 100 is adjusted. The relative movement of the inner core tube 1000 and the suction tube 3000 is controlled to ensure that the cavity opening 5200 of the thrombus puller 5000 is tightly attached to the blood vessel wall. Then, keeping the relative positions of the inner core tube 1000 and the suction tube 3000 fixed, the thrombus puller 5000 is pulled to gather the free thrombus and the thrombus attached to the blood vessel wall in the target blood vessel 100 into the filter thrombus cavity 5100 of the thrombus puller 5000 in one go. Once the thrombus has been completely collected, the thrombus fragment 6000 is pushed out of the suction tube 3000, positioning it approximately 1mm to 3mm proximal to the tip of the tube. Negative pressure is applied to draw the acute thrombus out through the suction tube 3000. At this point, the thrombus fragment 6000 can intercept large subacute thrombi, preventing thrombus blockage of the suction tube 3000. This is the process for acute thrombus removal.

[0084] After the acute thrombus is removed, aspiration is stopped. The thrombus fragmentation device 6000 is rotated, and the transmission tube 2000 can be moved back and forth to fragment the thrombus gathered in the thrombus puller 5000. The position of the thrombus fragmentation device 6000 is then adjusted to approximately 1mm to 3mm from the proximal end of the aspiration tube 3000 to prevent large, uncut thrombus fragments from clogging the aspiration tube 3000. Negative pressure is applied to extract the fragmented subacute thrombus from the body. When aspiration is complete, a small amount of subacute thrombus may remain in the thrombus puller 5000. At this point, the residual amount is relatively small. The thrombus fragmentation device is first retracted into the aspiration tube 3000, and then the thrombus puller 5000 is withdrawn from the body along the outer sheath 4000. The remaining small amount of subacute thrombus is then carried out of the body by the thrombus puller 5000. The thrombus removal is confirmed by angiography through the indwelling outer sheath 4000. The outer sheath 4000 is then withdrawn, and the procedure is completed.

[0085] Since the specific structure, functional principles, and technical effects of the aforementioned thrombus removal components or systems have been described in detail above, they will not be repeated here. Any relevant technical content can be found in the preceding descriptions. Furthermore, the aforementioned thrombus removal method describes the actual use of the thrombus removal components or systems, and therefore can be used to understand the technical content of the thrombus removal components or systems.

[0086] The technical features of the above embodiments can be combined in any way. For the sake of brevity, not all possible combinations of the technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0087] The embodiments described above are merely illustrative of several implementation methods of this application, and while the descriptions are relatively specific and detailed, they should not be construed as limiting the scope of the patent application. It should be noted that those skilled in the art can make various modifications and improvements without departing from the concept of this application, and these all fall within the protection scope of this application. Therefore, the protection scope of this patent application should be determined by the appended claims.

Claims

1. A thrombus removal component, characterized in that, The thrombus removal component includes: Inner core tube (1000); A transmission tube (2000) is movably sleeved on the outside of the inner core tube (1000); A suction tube (3000) is movably sleeved outside the transmission tube (2000), and the inner cavity of the suction tube (3000) is configured to form a suction channel. A thimble-pulling body (5000) has a filter plug cavity (5100) and a cavity opening (5200) communicating with the filter plug cavity (5100). The proximal end of the thimble-pulling body (5000) is connected to the inner core tube (1000), and the distal end of the thimble-pulling body (5000) is connected to the suction tube (3000). A puncture body (6000) is disposed at the proximal end of the transmission tube (2000) and is used to enter and exit the filter plug cavity (5100) of the pull plug body (5000) through the cavity port (5200) of the pull plug body (5000).

2. The thrombus removal component according to claim 1, characterized in that, The tube layer gap between the inner wall of the suction tube (3000) and the outer wall of the transmission tube (2000) is configured to form the suction channel; and / or, The plug body (5000) is configured to allow non-target bodies to flow through the plug cavity (5100) and retain target bodies in the plug cavity (5100); And / or, The pull-bolt body (5000) has a deformation capability for switching between a contracted state and an expanded state, and the relative movement between the inner core tube (1000) and the suction tube (3000) is configured to change the deformation state of the pull-bolt body (5000); and / or, The cavity opening (5200) of the thimble body (5000) is located at the distal end of the thimble body (5000), the inner cavity of the suction tube (3000) communicates with the cavity opening (5200) of the thimble body (5000), and the movement of the transmission tube (2000) relative to the suction tube (3000) is configured to control the thimble fragment (6000) to enter and exit the filter plug cavity (5100) of the thimble body (5000) through the cavity opening (5200) of the thimble body (5000); and / or, The suction tube (3000) is connected to the distal end of the pull-bolt body (5000) via a connector (5300); and / or, The break-in body (6000) has the ability to deform and switch between a contracted state and an expanded state, and the movement of the transmission tube (2000) relative to the suction tube (3000) is at least configured to change the deformation state of the pull-in body (5000).

3. The thrombus removal component according to claim 2, characterized in that, The non-target body is blood, and the target body is a thrombus; and / or, The bolt body (5000) is a filter structure; and / or, The surface of the bolt body (5000) is provided with a filter structure; and / or, The proximal end of the thimble body (5000) is closed, and the distal end of the thimble body (5000) is open to form the cavity (5200). The size of the thimble body (5000) gradually increases from the proximal end to the distal end; and / or, The suction tube (3000) has a plurality of first connection positions distributed in the circumferential direction, and the pull plug body (5000) has a plurality of second connection positions distributed at its distal end. One end of a plurality of connectors (5300) is connected to a plurality of the first connection positions of the suction tube (3000), and the other end of a plurality of connectors (5300) is connected to a plurality of the second connection positions of the pull plug body (5000); and / or, The connector (5300) and the bolt body (5000) are integrally formed.

4. The thrombus removal component according to claim 2, characterized in that, The fragmented thrombus (6000) includes: A break-off element (6100) is provided, the number of which is at least one, the break-off element (6100) has deformability, the break-off element (6100) is connected to the transmission tube (2000), and the break-off element (6100) is configured to be in force contact with the suction tube (3000) and to switch between a contracted state and an expanded state by interaction force relative to the suction tube (3000).

5. The thrombus removal component according to claim 4, characterized in that, At least one of the aforementioned break-fitting elements (6100) has one end connected to the transmission tube (2000), and the other end is in a suspended state not connected to the transmission tube (2000); and / or, Several of the aforementioned break-locking elements (6100) are arranged along the circumferential direction of the transmission tube (2000) on the outer wall of the tube.

6. The thrombus removal component according to claim 5, characterized in that, At least one of the said break-in elements (6100) is a linear structural element; and / or, At least one of the said break-off element (6100) is a linear element or a curved element; and / or, At least one of the bolt breaking elements (6100) is staggered relative to the other bolt breaking elements (6100) in the axial direction of the transmission tube (2000).

7. The thrombus removal component according to claim 6, characterized in that, Several of the aforementioned bolt-breaking elements (6100) are linear elements, arranged radially along the transmission tube (2000); or, Some of the aforementioned break-bolt elements (6100) are curved elements that bend from the inside to the outside along the radial direction of the transmission tube (2000).

8. The thrombus removal component according to claim 1, characterized in that, The thrombus removal component includes: An outer sheath (4000) is movably sleeved outside the suction tube (3000), and the inner cavity of the outer sheath (4000) is configured to receive the puller body (5000).

9. A thrombus removal system, characterized in that, The thrombus removal system includes the thrombus removal component as described in any one of claims 1-8.

10. A thrombus removal method based on the thrombus removal component according to any one of claims 1-8 or the thrombus removal system according to claim 9, characterized in that, The thrombus removal method includes the following steps: Control the relative movement of the inner core tube (1000) and the suction tube (3000) to adjust the deformation state of the pull plug body (5000) and capture the target body into the filter plug cavity (5100) of the pull plug body (5000); Control the relative movement of the transmission tube (2000) and the suction tube (3000), and use the plug fragment (6000) that enters the filter plug cavity (5100) to crush the target body in the filter plug cavity (5100); The pulverized target object is extracted through the suction channel.

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