An auxiliary hypolipidemic composition and use thereof

By using a specific ratio of Bifidobacterium lactis subsp. MN-Gup, microalgae oil, and phytosterol esters, the problem of unclear interactions in multi-component compound systems for assisting in lowering blood lipids was solved, achieving significant multi-target regulatory effects and providing a safe and effective auxiliary blood lipid-lowering solution.

CN122163665APending Publication Date: 2026-06-09INNER MONGOLIA MENGNIU DAIRY IND (GROUP) CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
INNER MONGOLIA MENGNIU DAIRY IND (GROUP) CO LTD
Filing Date
2026-05-13
Publication Date
2026-06-09

AI Technical Summary

Technical Problem

In existing technologies, multi-component compound systems have limitations in assisting in lowering blood lipids, including unclear interactions between active ingredients, lack of scientific evidence, insufficient reproducibility, and difficulty in balancing safety and efficacy, making it difficult to industrialize compound systems.

Method used

A composition using a specific ratio of Bifidobacterium animalis subsp. lactis MN-Gup, microalgae oil, and phytosterol esters significantly improves lipid metabolism through synergistic effects, reducing triglyceride, total cholesterol, and low-density lipoprotein cholesterol levels while increasing high-density lipoprotein cholesterol levels.

Benefits of technology

It achieves significant multi-target synergistic regulation, safely and effectively reduces total cholesterol and triglycerides, and increases high-density lipoprotein cholesterol, providing a safe and effective adjunctive lipid-lowering solution with good industrialization feasibility.

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Abstract

This invention relates to the field of functional product technology, and more particularly to a composition for assisting in lowering blood lipids and its application. The invention provides a composition comprising *Bifidobacterium animalis* subsp. *lactamase* MN-Gup, microalgae oil, and phytosterol esters. The composition of this invention can simultaneously and effectively reduce triglyceride and total cholesterol levels, particularly significantly reducing low-density lipoprotein cholesterol while increasing high-density lipoprotein cholesterol levels. Compared to each individual component, it exhibits significant advantages, demonstrating significant auxiliary lipid-lowering efficacy with good safety and industrial feasibility. This provides a basis for the development of auxiliary lipid-lowering products and offers a new intervention strategy for blood lipid health management.
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Claims

1. A composition, characterized in that, The composition is prepared in a ratio of 2×10 4 CFU: 4-40μg; Bifidobacterium lactis subsp. animalis: 49-139μg Bifidobacterium animalis subsp.lactis Composed of MN-Gup, microalgae oil, and phytosterol esters; The *Bifidobacterium animalis* subspecies *Lactobacillus* MN-Gup is deposited at the China General Microbiological Culture Collection Center (CGMCC) with accession number CGMCC No. 15578.

2. The composition according to claim 1, characterized in that, In the composition, the ratio of Bifidobacterium animalis subsp. lactis MN-Gup, microalgal oil, and phytosterol esters is 2 × 10⁻⁶. 4 CFU: 19.6-40μg: 49-100μg.

3. The composition according to claim 1, characterized in that, The microalgae oil is EPA microalgae oil.

4. The composition according to claim 3, characterized in that, The microalgae oil contains ≥12% EPA and ≥20% ALA by mass.

5. The use of the composition according to any one of claims 1 to 4 in the preparation of health food products that help maintain healthy blood lipid levels.

6. The use of the composition according to any one of claims 1 to 4 in the preparation of health foods that assist in lowering blood lipids or improving blood lipid metabolism.

7. Use of the composition according to any one of claims 1 to 4 in the preparation of lipid-lowering drugs or drugs for treating hyperlipidemia.

8. The use of the composition according to any one of claims 1 to 4 in adjuvant lipid-lowering or maintenance of healthy lipid levels for non-disease treatment purposes.

9. A product characterized in that, The product comprises the composition according to any one of claims 1 to 4.

10. The product according to claim 9, characterized in that, The product is either a health food or a medicine.