Bacterial detection nanoparticle and preparation method and application thereof

CN122164892APending Publication Date: 2026-06-09JIHUA LAB

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
JIHUA LAB
Filing Date
2024-12-06
Publication Date
2026-06-09

AI Technical Summary

Technical Problem

Existing bacterial detection methods suffer from problems such as complex operation, long detection time, and high false positive rate, which have not been effectively resolved.

Method used

Gold nanoparticles modified with maltohexasose were used to achieve specific binding and intuitive detection of bacteria through color changes. The preparation method included dissolving maltohexasose in deionized water and reacting it with HAuCl4 solution, followed by centrifugation and filtration sterilization.

Benefits of technology

This provides a simple and easy-to-implement large-scale preparation method that can specifically bind to bacteria, allowing for intuitive detection of bacteria through color changes and reducing the risk of false positives.

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Abstract

The application relates to the technical field of nanomaterials, and mainly relates to a bacteria detection nanoparticle and a preparation method and application thereof. The bacteria detection nanoparticle comprises gold nanoparticles, and the gold nanoparticles are modified with maltotriose. The preparation method is simple in process and easy to operate, is favorable for large-scale preparation of the bacteria detection nanoparticle, and the prepared gold nanoparticles modified with maltotriose can be specifically combined with bacteria, bacteria can be directly detected through color change, and the bacteria detection application has important significance.
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