Cell chip

By using a cell chip-based resuscitation and refrigeration preservation method, the problem of reduced detectability during cell refrigeration preservation has been solved, thereby improving the detectability of odor substances and increasing preparation efficiency.

CN122180760APending Publication Date: 2026-06-09SUMITOMO CHEM CO LTD
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Patent Information

Application Number
CN202480072277.7
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Priority Date
2023-10-06
Filing Date
2024-10-01
Publication Date
2026-06-09

AI Technical Summary

Technical Problem

In existing odor sensors, the detectability of odor substances decreases when cells are refrigerated, and the preparation efficiency is insufficient. There is a need to improve the detectability of odor substances when cells are refrigerated.

Method used

Cell microarrays were used for cryopreservation with resuscitation culture. The temperature was set below 10°C, the resuscitation culture temperature was above 12°C, the cryopreservation period was more than 3 days and less than 14 days, and the resuscitation culture period was more than 1 day and less than 14 days. Insect cells containing sensor protein coding sequences were preferred, and specific culture media and gel solvents were used for preservation.

Benefits of technology

It improves the detectability of chemicals such as odor substances, ensures the detection effect of cells during cold storage, simplifies the operation process, and reduces cell damage.

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Abstract

Provided is a technology capable of improving the detectability of chemical substances such as odor substances when cells are cryopreserved. A cell chip containing cells for cryopreservation with recovery culture.
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Citation Information

Patent Citations

  • Mutant insect olfactory receptor protein

    WO2022024902A1