sample analyser
By using a camera mechanism to capture images of the reaction solution in a sample analyzer and combining this with optical detection, the problem of detecting the volume of the reaction solution and bubbles or foreign matter in coagulation testing has been solved, thus improving the accuracy of the test results.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- BEIJING PRECIL INSTR CO LTD
- Filing Date
- 2024-12-12
- Publication Date
- 2026-06-12
AI Technical Summary
Existing technologies are insufficient to accurately detect the volume of the reaction solution and the presence of air bubbles or foreign matter in coagulation tests, which affects the accuracy of the test results.
Images of the reaction solution are captured using a camera mechanism. Image analysis is used to determine whether the volume of the reaction solution is abnormal and whether there are bubbles or foreign objects. Further detection is then carried out using optical methods.
It enables accurate detection of the volume of the reaction liquid and bubbles or foreign matter, improving the reliability and accuracy of the detection results.
Smart Images

Figure CN122193213A_ABST
Abstract
Description
Technical Field
[0001] This invention relates to the field of medical device technology, and in particular to a sample analyzer. Background Technology
[0002] In fully automated coagulation analyzers, strict control over the addition of samples and reagents is crucial for obtaining accurate results. Methods for monitoring liquid volume typically include pressure detection and level detection. Pressure detection checks the pressure during addition to determine if there is any cavitation or needle blockage; the absence of these issues indicates accurate addition. Level detection uses the change in capacitance (the signal at the liquid level before and after addition) to determine if liquid has been added to the reaction vessel. However, some coagulation tests require only a few microliters of sample, which current pressure and level detection methods cannot adequately meet. Furthermore, the reaction solution (the mixture of sample and reagents) may generate bubbles and other interference during coagulation testing, affecting the accuracy of optical results. Currently, this interference can only be analyzed and estimated from optical curves or results (if anomalies are found), lacking direct detection methods. Summary of the Invention
[0003] The present invention aims to at least solve one of the technical problems existing in the prior art. To this end, the present invention proposes a sample analyzer capable of detecting abnormalities in the volume of a reaction solution, and / or capable of detecting the presence of air bubbles or foreign matter in the reaction solution.
[0004] The sample analyzer according to the first embodiment of the present invention includes: A detection position is used to place a first reaction container containing a first reaction solution that has undergone incubation treatment, the first reaction solution being made from at least the sample to be tested and a reagent; A measuring mechanism is used to measure the first reaction liquid loaded in the first reaction container located at the detection position to obtain sample detection data. A transfer mechanism is used to transfer the first reaction container containing the measured first reaction liquid to the cup throwing position, and to throw the first reaction container into the reaction cup recovery mechanism at the cup throwing position. A first camera mechanism is configured to perform a first image capture action on the measured first reaction liquid loaded in the first reaction container at the detection position, at the cup-throwing position, or during the process of the transfer mechanism transferring the first reaction container loaded with the measured first reaction liquid from the detection position to the cup-throwing position. A control device configured to: obtain a first target image based on the image captured by the first camera mechanism performing the first shooting action; and output at least one of the following information based on the first target image: the first target image, a determination result of whether the volume of the first reaction liquid is abnormal, and a determination result of whether there are bubbles or foreign objects in the first reaction liquid. The first target image includes at least an image showing the first reaction liquid in a two-dimensional and / or three-dimensional form, and at least the first target image is used as a basis for determining whether the volume of the first reaction liquid is abnormal and / or as a basis for determining whether the first reaction liquid contains bubbles or foreign matter.
[0005] The sample analyzer according to embodiments of the present invention has at least the following beneficial effects: In this embodiment, by taking a first photograph of the measured first reaction liquid, a first target image can be obtained. Then, based on the first target image, at least one piece of information can be output: the first target image, a determination result of whether the volume of the first reaction liquid is abnormal, and a determination result of whether there are bubbles or foreign objects in the first reaction liquid, thereby facilitating the identification of abnormalities in the reaction liquid.
[0006] In other embodiments of the present invention, the step of outputting at least one of the following information based on the first target image: the first target image, a determination result of whether the volume of the first reaction liquid is abnormal, and a determination result of whether there are bubbles or foreign objects in the first reaction liquid, includes: outputting the first target image; Alternatively, the step of outputting at least one of the following information based on the first target image: the first target image, the volume of the first reaction liquid, a determination result of whether the volume of the first reaction liquid is abnormal, and a determination result of whether there are bubbles or foreign objects in the first reaction liquid, includes: outputting the first target image, and outputting at least one of the determination result of whether the volume of the first reaction liquid is abnormal and the determination result of whether there are bubbles or foreign objects in the first reaction liquid.
[0007] In other embodiments of the present invention, the first target image is used as at least as a basis for determining whether the volume of the first reaction solution is abnormal, including: The volume of the first reaction liquid in the first reaction container is obtained based on the first target image, and the volume of the first reaction liquid is determined to be abnormal based on whether the volume value is within a first preset range; and / or, Based on the height value of the first reaction liquid loaded in the first reaction container obtained from the first target image, it is determined whether the volume of the first reaction liquid is abnormal based on whether the height value is within a second preset range.
[0008] In other embodiments of the present invention, it further includes: A sample dispensing mechanism, the sample dispensing mechanism being used to aspirate at least a portion of the test sample from the sample container and dispense all or part of the aspirated test sample into the first reaction container; The second camera mechanism is used to perform a second shooting action on the first reaction container that only contains the sample to be tested before the measuring mechanism measures the first reaction liquid loaded in the first reaction container. The control device is configured to: obtain a second target image based on the image captured by the second shooting action performed by the second camera mechanism; At least the first target image is used as a basis for determining whether the volume of the first reaction liquid is abnormal, including: obtaining the change in the volume of the liquid loaded in the first reaction container based on the second target image and the first target image, and determining whether the volume of the first reaction liquid is abnormal based on whether the change in the volume of the liquid loaded in the first reaction container is within a third preset range. The first camera mechanism and the second camera mechanism are the same institution, or the first camera mechanism is set up independently of the second camera mechanism.
[0009] In other embodiments of the present invention The measuring mechanism is constructed as a photometric component that measures the first reaction liquid in at least a local area loaded in the first reaction vessel based on an optical method. At least the first target image is used as a basis for determining whether the first reaction liquid contains bubbles or foreign matter, including: obtaining an image of the first reaction liquid in at least the local area loaded in the first reaction container based on the first target image, and determining whether bubbles or foreign matter exist in the first reaction liquid based on whether the image of the local area contains features that characterize bubbles or foreign matter.
[0010] In other embodiments of the present invention, the first target image is used as a basis for determining whether the first reaction liquid contains bubbles or foreign matter, including: extracting the first target image to obtain a target index for characterizing the light spot, and determining whether the first reaction liquid contains bubbles or foreign matter based on whether the target index is greater than a preset index; and / or, Extract target features from the first target image, and determine whether the first reaction liquid contains bubbles or foreign matter based on whether the similarity between the target features and preset features is greater than a preset threshold.
[0011] In other embodiments of the present invention, it further includes: A reaction vessel supply mechanism, wherein the reaction vessel supply mechanism is used to output the first reaction vessel; A sample dispensing mechanism, the sample dispensing mechanism being used to aspirate at least a portion of the sample to be tested from a sample container and dispense all or part of the aspirated sample to be tested into the first reaction container; A reagent dispensing mechanism is used to draw at least a portion of the reagent from a reagent container from a reagent container storage mechanism and dispense all or part of the drawn reagent into a first reaction container, wherein the first reaction solution is prepared in the first reaction container from at least the test sample and the reagent; An incubation apparatus, wherein the incubation apparatus is used to perform the incubation treatment on the first reaction liquid loaded in the first reaction vessel; The sample dispensing mechanism and the reagent dispensing mechanism are the same mechanism, or the sample dispensing mechanism is set up independently of the reagent dispensing mechanism.
[0012] In other embodiments of the present invention, the reaction vessel supply mechanism is also used to output a second reaction vessel; The control device is configured to: when it is determined from the first target image that the volume of the first reaction liquid loaded in the first reaction container is abnormal, or when it is determined from the first target image that there are bubbles or foreign objects in the first reaction liquid loaded in the first reaction container, control the reaction container supply mechanism to output the second reaction container, control the sample dispensing mechanism to draw at least a portion of the sample to be tested from the sample container and dispense all or part of the drawn sample to the second reaction container, control the reagent dispensing mechanism to draw at least a portion of the reagent from the reagent container from the reagent container storage mechanism and dispense all or part of the drawn reagent to the second reaction container, wherein the second reaction liquid is prepared in the second reaction container at least by the sample to be tested and the reagent, control the incubation mechanism to incubate the second reaction liquid loaded in the second reaction container, and control the measuring mechanism to measure the second reaction liquid loaded in the second reaction container to obtain sample retest data; The first reaction vessel and the second reaction vessel are reaction vessels of the same specifications, or the first reaction vessel and the second reaction vessel are reaction vessels of different specifications.
[0013] In other embodiments of the present invention, the following are included: A sample storage mechanism, comprising a loading area and a buffer area, both of which are used to support sample racks containing sample containers; A sample scheduling mechanism is used to schedule sample racks so that sample containers placed on the sample racks are scheduled from the loading area to the sampling position, and so that sample containers placed on the sample racks are scheduled from the sampling position to the buffer area. The control device is configured to: after the sample dispensing mechanism draws the sample to be tested from the sample container and dispenses it into the first reaction container, control the sample scheduling mechanism to schedule the sample rack carrying the sample container to the buffer area for buffering. The controller is further configured to: when it is determined from the first target image that the volume of the first reaction solution is abnormal, and / or when it is determined from the first target image that there are bubbles or foreign matter in the first reaction solution, control the sample scheduling mechanism to schedule the sample rack carrying the sample container for preparing the first reaction solution, so that the sample container is rescheduled from the buffer area to the aspiration position; control the sample dispensing mechanism to re-absorb at least a portion of the sample to be tested from the sample container located at the aspiration position and dispense all or part of the aspirated sample to be tested into the second reaction container; control the reagent dispensing mechanism to aspirate at least a portion of the reagent from the reagent container from the reagent container storage mechanism and dispense all or part of the aspirated reagent into the second reaction container, wherein the second reaction solution is prepared in the second reaction container at least by the sample to be tested and the reagent; and control the measuring mechanism to measure the second reaction solution loaded in the second reaction container after incubation treatment to obtain sample retest data. The first reaction vessel and the second reaction vessel are reaction vessels of the same specifications, or the first reaction vessel and the second reaction vessel are reaction vessels of different specifications.
[0014] In other embodiments of the present invention, the sample storage mechanism further includes an unloading area for placing the sample container that has been aspirated by the sample distribution mechanism and measured by the measuring mechanism to achieve the recovery of the sample container. The controller is further configured to: when it is determined from the first target image that there is no abnormality in the volume of the first reaction liquid, and when it is determined from the first target image that there are no bubbles or foreign objects in the first reaction liquid, control the sample scheduling mechanism to schedule the sample rack so that the sample container placed on the sample rack is scheduled from the buffer area to the unloading area.
[0015] In other embodiments of the present invention The first camera mechanism is used to perform a first imaging action on the first reaction liquid in the first reaction container during the process of transferring the first reaction container containing the measured first reaction liquid from the detection position to the throwing position in the transfer mechanism, including: The first camera is positioned close to the detection position, and the first camera performs a first shooting action on the first reaction container located at the detection position, which is loaded with the measured first reaction liquid. Alternatively, the first camera is positioned close to the cup-throwing position, and the first camera performs a first shooting action on the first reaction container located at the cup-throwing position, which contains the measured first reaction liquid. Alternatively, the first camera mechanism is positioned close to the shooting position, which is independent of the detection position and the cup-throwing position. The transfer mechanism transfers the first reaction container containing the measured first reaction liquid from the detection position to the shooting position. The first camera mechanism performs a first shooting action on the first reaction container containing the measured first reaction liquid located at the shooting position. Alternatively, the first camera mechanism is mounted on the transfer mechanism, and the first camera mechanism performs a first shooting action on the first reaction container located on the transfer mechanism, which contains the measured first reaction liquid.
[0016] In other embodiments of the present invention, the control device is configured to: obtain the test result of the sample to be tested based on the sample test data obtained by the measuring mechanism measuring the first reaction liquid, and control the first camera mechanism to perform the first shooting action based on the test result of the sample to be tested.
[0017] In other embodiments of the present invention, controlling the first camera mechanism to perform the first shooting action based on the detection result of the sample to be tested includes: controlling the first camera mechanism to perform the first shooting action when it is determined that the detection result of the sample to be tested is not within a fourth preset range; or, If it is determined that the detection result of the sample to be tested cannot be obtained, the first camera mechanism is controlled to perform the first shooting action.
[0018] In other embodiments of the present invention The sample container has a cap, and the sample dispensing mechanism includes a sample needle, which is a puncture needle with a puncture function. The sample needle is used to puncture the cap of the sample container to at least partially penetrate the sample container and draw up the sample to be tested and dispense it into the first reaction container.
[0019] In other embodiments of the present invention The measuring mechanism is constructed as a photometric component that measures the first reaction liquid in at least a local area loaded in the first reaction container using an optical method. The control device is configured to adjust the wavelength or power of the light beam of the photometric component according to the hemolysis index, lipemia index, or jaundice index of the sample to be tested.
[0020] Additional aspects and advantages of the invention will be set forth in part in the description which follows, and in part will be obvious from the description, or may be learned by practice of the invention. Attached Figure Description
[0021] The present invention will be further described below with reference to the accompanying drawings and embodiments, wherein: Figure 1 This is a schematic diagram of the sample analyzer in an embodiment of the present invention; Figure 2 This is a schematic diagram of a first camera mechanism capturing an image of a first reaction container located at a detection position, according to an embodiment of the present invention. Figure 3 This is a schematic diagram of a first camera mechanism taking a picture of a first reaction vessel located at the cup-throwing position in one embodiment of the present invention; Figure 4 This is a schematic diagram of a first camera mechanism taking a picture of a first reaction container located at the shooting position in one embodiment of the present invention.
[0022] Figure label: Sample analyzer 10, first camera mechanism 100, sample loading position 104, transfer mechanism 200, measuring mechanism 300, sample dispensing mechanism 400, reagent dispensing mechanism 500, reagent container storage mechanism 600, sample injection mechanism 700, reaction container supply mechanism 800, incubation mechanism 900; First reaction vessel 20; Detection position 101, cup throwing position 102, shooting position 103, second camera mechanism 105. Detailed Implementation
[0023] Embodiments of the present invention are described in detail below. Examples of these embodiments are shown in the accompanying drawings, wherein the same or similar reference numerals denote the same or similar elements or elements having the same or similar functions throughout. The embodiments described below with reference to the accompanying drawings are exemplary and are only used to explain the present invention, and should not be construed as limiting the present invention.
[0024] In the description of this invention, it should be understood that the orientation descriptions, such as up, down, front, back, left, right, etc., are based on the orientation or positional relationship shown in the accompanying drawings. They are only for the convenience of describing this invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limiting this invention.
[0025] In the description of this invention, "several" means one or more, "multiple" means two or more, "greater than," "less than," and "exceeding" are understood to exclude the stated number, while "above," "below," and "within" are understood to include the stated number. The use of "first" and "second" in the description is merely for distinguishing technical features and should not be construed as indicating or implying relative importance, or implicitly indicating the number of indicated technical features, or implicitly indicating the order of the indicated technical features.
[0026] In the description of this invention, unless otherwise explicitly defined, terms such as "set up," "install," and "connect" should be interpreted broadly, and those skilled in the art can reasonably determine the specific meaning of the above terms in this invention in conjunction with the specific content of the technical solution.
[0027] In the description of this invention, the terms "one embodiment," "some embodiments," "illustrative embodiment," "example," "specific example," or "some examples," etc., refer to specific features, structures, materials, or characteristics described in connection with that embodiment or example, which are included in at least one embodiment or example of the invention. In this specification, the illustrative expressions of the above terms do not necessarily refer to the same embodiment or example. Furthermore, the specific features, structures, materials, or characteristics described may be combined in any suitable manner in one or more embodiments or examples.
[0028] In sample analysis, a reaction solution needs to be prepared using sample solution and reagents. The reaction solution is then incubated before being detected to obtain results. Abnormalities in the sample addition and / or reagent addition stages, such as adding too much or too little solution, or failure to add it to the reaction container, will lead to abnormalities in the volume of the reaction solution. Simultaneously, samples and reagents typically require low-temperature storage, resulting in a relatively low temperature for the reaction solution. When the reaction solution is heated during incubation, changes in solubility can cause gas release, generating bubbles within the reaction solution. Furthermore, foreign matter may be generated in the reaction container during the reaction process, or external foreign matter may be introduced. These abnormalities in the reaction solution volume, the presence of bubbles, or the presence of foreign matter (collectively referred to as "reaction solution abnormalities" in some descriptions of this embodiment for ease of explanation) can all affect the detection results. Based on this, the present invention proposes a sample analyzer 10 capable of detecting reaction solutions based on images to identify abnormalities in the reaction solution volume, the presence of bubbles, or foreign matter within the reaction solution. The following description, in conjunction with the accompanying drawings and specific embodiments, provides further details.
[0029] Reference Figures 1 to 4 The sample analyzer 10 in the first aspect embodiment of the present invention includes a measuring mechanism 300, a transfer mechanism 200, a first camera mechanism 100, and a control device. Furthermore, the sample analyzer 10 also includes a detection position 101 and a cup-throwing position 102. It should be noted that the detection position 101 is a fixed position for placing the first reaction container 20 and facilitating detection by the measuring mechanism 300. For example, when the first reaction container 20 is placed on a support corresponding to the measuring mechanism 300, it can be considered that the first reaction container 20 is placed at the detection position 101. The cup-throwing position 102 is the position where the first reaction container 20 is thrown towards the reaction cup recovery mechanism. For example, the reaction cup recovery mechanism has an upward-facing opening, and the cup-throwing position 102 is located above this opening.
[0030] Specifically, detection position 101 is used to place the first reaction container 20, which contains a first reaction solution after incubation treatment. The first reaction solution is made from at least the sample to be tested and reagents. Measurement mechanism 300 is used to measure the first reaction solution contained in the first reaction container 20 located at detection position 101 to obtain sample detection data. For example, measurement mechanism 300 can be a photometric mechanism 300. It should be noted that detection position 101 can be set to one or multiple locations. Figure 1 As shown in the example, the sample analyzer 10 is provided with multiple detection positions 101, and the multiple detection positions 101 are along... Figure 1 The detectors are spaced out in the left and right directions. For ease of viewing, only the rightmost detector is marked in the image.
[0031] The transfer mechanism 200 is used to transfer the first reaction container 20, which contains the measured first reaction liquid, from the detection position 101 to the cup-throwing position 102, and then throw the first reaction container 20 into the reaction cup recovery mechanism at the cup-throwing position 102. Exemplarily, the transfer mechanism 200 includes a robotic arm and a drive device for moving the robotic arm in a three-dimensional or two-dimensional direction. After the robotic arm grasps the first reaction container 20 at the detection position 101, it is moved to the cup-throwing position 102 by the drive device. Then, the robotic arm releases the first reaction container 20, causing it to fall into the reaction cup recovery mechanism under gravity. It should be noted that the transfer mechanism 200 can transfer the first reaction container 20 without stopping, or it can first transfer the first reaction container 20 from the detection position 101 to another position, and then transfer it from that position to the cup-throwing position 102. This will be explained in subsequent embodiments.
[0032] The first camera mechanism 100 is used to perform a first imaging action on the measured first reaction liquid inside the first reaction container 20. In this embodiment, the first camera mechanism 100 images the first reaction liquid after the measuring mechanism 300 has completed the measurement of the first reaction liquid. It should be noted that "completed measurement" or "measured" includes both the measuring mechanism 300 having completed the detection step but not yet obtained sample detection data, and the measuring mechanism 300 having already obtained sample detection data. In other words, the first camera mechanism 100 can perform the first imaging action after the measuring mechanism 300 has completed the detection step and before obtaining sample detection data, or it can perform the first imaging action after the measuring mechanism 300 has obtained sample detection data. In addition, in this embodiment, the imaging position of the first camera mechanism 100 on the first reaction liquid can be at the detection position 101 (e.g., Figure 2 As shown), cup-throwing position 102 (as shown) Figure 3 (As shown) or at any position during the process of the transfer mechanism 200 transferring the first reaction vessel 20 from the detection position 101 to the cup-throwing position 102 (as shown) Figure 4 (As shown) to perform the test.
[0033] In this embodiment, the control device is configured to: obtain a first target image based on the image captured by the first camera mechanism 100 performing a first shooting action; and output at least one of the following information based on the first target image: ① the first target image; ② a determination result of whether the volume of the first reaction liquid is abnormal; ③ a determination result of whether there are bubbles or foreign objects in the first reaction liquid.
[0034] The above information can directly or indirectly indicate whether the reaction liquid has the aforementioned abnormalities. For example, when the first target image is output through the first target image (that is, the first target image is output directly or after processing), the user can directly view the state of the first reaction liquid in the first target image, such as the liquid level of the first reaction liquid, whether there are bubbles, etc., and thus judge whether the reaction liquid has any abnormalities.
[0035] For example, when outputting a judgment result on whether the volume of the first reaction liquid is abnormal, the control device completes the judgment process of abnormal volume based on the first target image, thereby directly outputting a judgment result that is easy for the user to identify. The judgment result can be presented in the form of text, graphics, sound, or a combination thereof. For example, the control device obtains the volume of the first reaction liquid through the first target image and compares it with the stored set volume to determine whether the volume is too low or too high. If so, the control device outputs text or image information that can directly represent whether the volume is high or low.
[0036] For example, when the output is the determination result of whether there are bubbles or foreign objects in the first reaction liquid, the control device completes the determination process of whether there are bubbles or foreign objects, and directly outputs the determination result that is easy for the user to identify. The determination result can be presented in the form of text, graphics, sound or a combination thereof. For example, when the control device obtains that there are bubbles in the first reaction liquid through the first target image, the control device outputs text and image information that can directly characterize the presence of bubbles in the reaction liquid.
[0037] In order to achieve the purpose of directly characterizing or indirectly judging anomalies through the first target image, the first target image includes at least an image of the first reaction liquid displayed in a two-dimensional and / or three-dimensional form, and at least the first target image is used as a basis for judging whether the volume of the first reaction liquid is abnormal and / or as a basis for determining whether there are bubbles or foreign objects in the first reaction liquid, for example, as a basis for user self-judgment or as a basis for judgment by the control device.
[0038] It should be noted that the aforementioned information can be output individually or in combination.
[0039] It should also be noted that the output usually indicates an abnormality when there is an abnormality in the reaction solution. In other words, if no abnormality is output, it can be assumed that an abnormality is not present.
[0040] In this embodiment, by taking a first photograph of the measured first reaction liquid, a first target image can be obtained. Then, based on the first target image, at least one piece of information can be output: the first target image, a determination result of whether the volume of the first reaction liquid is abnormal, and a determination result of whether there are bubbles or foreign objects in the first reaction liquid, thereby facilitating the identification of abnormalities in the reaction liquid.
[0041] Based on the first embodiment, in some embodiments of the present invention, the aforementioned "outputting at least one of the following information based on the first target image: the first target image, the determination result of whether the volume of the first reaction liquid is abnormal, and the determination result of whether there are bubbles or foreign objects in the first reaction liquid" specifically refers to: outputting the first target image based on the first target image, that is, directly outputting the first target image obtained by the control device based on the image captured by the first camera mechanism 100, or outputting it after processing. For example, when there are bubbles or foreign objects in the reaction liquid, the bubbles or foreign objects are identified in the first target image.
[0042] Based on the first embodiment, in some embodiments of the present invention, the aforementioned "outputting at least one of the following information based on the first target image: the first target image, a determination result of whether the volume of the first reaction liquid is abnormal, and a determination result of whether there are bubbles or foreign objects in the first reaction liquid" specifically refers to: outputting the first target image based on the first target image, and outputting at least one of the determination result of whether the volume of the first reaction liquid is abnormal and the determination result of whether there are bubbles or foreign objects in the first reaction liquid. That is, this embodiment can directly output the determination result on the one hand, and output the first target image on the other hand, so as to facilitate the user to check whether the determination result output by the control device is correct.
[0043] Based on the first embodiment, in some embodiments of the present invention, the aforementioned "first target image used as at least as a basis for determining whether the volume of the first reaction liquid is abnormal" specifically refers to: obtaining the volume value of the first reaction liquid loaded in the first reaction container 20 based on the first target image, and determining whether the volume of the first reaction liquid is abnormal based on whether the volume value is within a first preset range. For example, when the volume value is lower than the lower limit of the first preset range or higher than the upper limit of the first preset range, it is determined that the volume is abnormal, thereby outputting a determination result that the volume of the first reaction liquid is abnormal. In this embodiment, the volume value of the first reaction liquid can be obtained from the first target image using a known visual algorithm.
[0044] In other embodiments, the aforementioned "first target image used as at least as a basis for determining whether the volume of the first reaction liquid is abnormal" specifically refers to: obtaining the height value of the first reaction liquid loaded in the first reaction container 20 based on the first target image, and determining whether the volume of the first reaction liquid is abnormal based on whether the height value is within a second preset range. For example, when the height value is lower than the lower limit of the second preset range or higher than the upper limit of the second preset range, it is determined that the volume is abnormal, thereby outputting a determination result that the volume of the first reaction liquid is abnormal. In this embodiment, the height value of the first reaction liquid can be obtained from the first target image using a known visual algorithm.
[0045] Based on the first embodiment, in some embodiments of the present invention, the sample analyzer 10 further includes a sample dispensing mechanism 400 and a second camera mechanism 105. The sample dispensing mechanism 400 is used to draw at least a portion of the sample to be tested from the sample container and dispense all or part of the drawn sample to the first reaction container 20. For example, the sample dispensing mechanism 400 includes a sample needle and a driving mechanism for moving the sample needle in a two-dimensional or three-dimensional direction. The sample needle can be driven by the driving mechanism to draw the sample to be tested from the sample container located at the sampling position and dispense the drawn sample to the first reaction container 20 located at the sample dispensing position 104.
[0046] The second camera mechanism 105 is used to perform a second imaging action on the first reaction container 20, which contains only the sample to be tested, before the measuring mechanism 300 measures the first reaction liquid loaded in the first reaction container 20. That is, the second camera mechanism 105 is used to perform the second imaging action after the sample dispensing mechanism 400 has completed the sample addition action to the first reaction container 20, but before the reagent dispensing mechanism 500 has performed the reagent addition action to the first reaction container 20. The control device is configured to obtain a second target image based on the image captured by the second camera mechanism 105 performing the second imaging action.
[0047] Based on this, the aforementioned "at least the first target image is used as the basis for determining whether the volume of the first reaction liquid is abnormal" specifically refers to: obtaining the change in the volume of the liquid loaded in the first reaction container 20 based on the second target image and the first target image, and then determining whether the volume of the first reaction liquid is abnormal based on whether the change in the volume of the liquid loaded in the first reaction container 20 is within a third preset range. For example, when the change in the volume of the liquid is lower than the lower limit of the third preset range or higher than the upper limit of the third preset range, it is determined that the volume is abnormal, and thus the determination result that the volume of the first reaction liquid is abnormal can be output.
[0048] Specifically, taking the example of the liquid volume change being lower than the lower limit of the third preset range, after the sample dispensing mechanism 400 dispenses the sample to be tested into the first reaction container 20, it is also necessary to dispense reagents into the first reaction container 20 through the reagent dispensing structure. Since the reagents are added, the liquid volume of the first reaction liquid should be greater than the liquid volume of the sample to be tested, and the increase value needs to be within the set third range. If the reagents are not successfully added or are insufficiently added, the liquid volume will not increase or will increase insufficiently. At this time, it can be determined whether there is an abnormality in the liquid volume of the first reaction liquid.
[0049] It should be noted that in the above process, the volume of the sample to be tested and the volume of the first reaction solution can be obtained first through the second target image and the first target image respectively, and then the change in volume can be obtained. Alternatively, the change in volume can be obtained directly by comparing the second target image and the first target image through relevant algorithms, without needing to obtain the specific volume values of the sample to be tested and the first reaction solution separately.
[0050] In some embodiments, the first camera mechanism 100 and the second camera mechanism 105 are the same mechanism, thereby reducing equipment costs. In other embodiments, the first camera mechanism 100 is set independently of the second camera mechanism 105. For example, the first camera mechanism 100 captures images of the first reaction container 20 at the detection position 101, while the second camera mechanism 105 captures images of the first reaction container 20 at the sample loading position 104. This reduces the frequency of scheduling actions where the first reaction container 20 is frequently dispatched to the first camera mechanism 100 due to different shooting actions.
[0051] It should be noted that the first shooting action performed by the first camera mechanism 100 can obtain one image or multiple images. Similarly, the second shooting action performed by the second camera mechanism 105 can obtain one image or multiple images.
[0052] Based on the first embodiment, in some embodiments of the present invention, the measuring mechanism 300 is configured as a photometric component for measuring the first reaction liquid in at least a local area loaded in the first reaction container 20 based on an optical method. For example, it can emit a detection beam to the first reaction container 20 located at the detection position 101. The detection beam illuminates a local area of the first reaction container 20 and is emitted. The emitted beam is received by a light receiving device to obtain sample detection data.
[0053] In this embodiment, the aforementioned "at least the first target image is used as a basis for determining whether there are bubbles or foreign objects in the first reaction liquid" specifically refers to: acquiring an image of at least a local area of the first reaction liquid loaded in the first reaction container 20 based on the first target image, and determining whether there are bubbles or foreign objects in the first reaction liquid based on whether the image of the local area contains features that characterize bubbles or foreign objects. It should be noted that when detection is performed using optical methods, the presence of foreign objects or bubbles in the optical path can significantly affect the detection results, while the presence of foreign objects or bubbles in other areas has little or no impact on the detection results. Therefore, this embodiment uses the image of a local area detected by the optical component on the first reaction container 20 as the basis for judging anomalies, which can eliminate interference from other areas and thus improve the accuracy of anomaly judgment. For example, the local area in this embodiment specifically refers to the spot area formed after the detection beam irradiates the first reaction container 20.
[0054] In other embodiments, the aforementioned "at least the first target image is used as the basis for determining whether there are bubbles or foreign objects in the first reaction liquid" further includes: extracting target features from the first target image, and determining whether there are bubbles or foreign objects in the first reaction liquid based on whether the similarity between the target features and preset features is greater than a preset threshold. For example, when the similarity between the target features and preset features is greater than or equal to the preset threshold, they are similar, and it is determined that there are bubbles or foreign objects in the first reaction liquid; when the similarity between the target features and preset features is less than the preset threshold, they are not similar, and it is determined that there are no bubbles or foreign objects in the first reaction liquid.
[0055] Based on the first embodiment, in some embodiments of the present invention, the sample analyzer 10 further includes a reaction vessel supply mechanism 800, a sample dispensing mechanism 400, and an incubation mechanism 900. During operation, the sample analyzer 10 continuously uses empty reaction vessels to complete different test items, and the reaction vessel supply mechanism 800 is used to output empty first reaction vessels 20.
[0056] The sample dispensing mechanism 400 is used to draw at least a portion of the test sample from the sample container and dispense all or part of the drawn test sample into the empty first reaction container 20, as can be understood with reference to the foregoing embodiments. The reagent dispensing mechanism 500 is used to draw at least a portion of the reagent from the reagent container storage mechanism 600 and dispense all or part of the drawn reagent into the first reaction container 20, such that a first reaction solution is prepared in the first reaction container 20 by at least the test sample and the reagent. Exemplarily, the reagent dispensing mechanism 500 includes a reagent needle and a driving mechanism for moving the reagent needle in a two-dimensional or three-dimensional direction. The reagent needle can be driven by the driving mechanism to draw reagent from the reagent container located at the reagent aspiration position and dispense the drawn reagent into the first reaction container 20 located at the reagent dispensing position.
[0057] The reagent container storage mechanism 600 is used to hold reagent containers. Typically, the reagent container storage mechanism 600 provides cooling or other functions for the reagents it holds, thereby ensuring the reagents' activity. To ensure the cooling effect, the reagent container storage mechanism 600 can be a closed structure; for example, it can be equipped with a reagent lid for heat preservation. In some specific embodiments, the reagent container storage mechanism 600 has multiple positions for holding reagent containers, and the reagent container storage mechanism 600 can rotate, causing the reagent containers it holds to rotate.
[0058] The incubation mechanism 900 is used to incubate the first reaction liquid loaded in the first reaction container 20, for example, by heating the first reaction liquid to 37°C for incubation.
[0059] In some embodiments, the sample dispensing mechanism 400 and the reagent dispensing mechanism 500 are the same mechanism, thereby reducing equipment costs. In other embodiments, the sample dispensing mechanism 400 is set independently of the reagent dispensing mechanism 500, and the independent dispensing of samples and reagents is achieved through different mechanisms, which can improve efficiency.
[0060] When the sample analyzer 10 further includes the aforementioned reaction vessel supply mechanism 800, sample dispensing mechanism 400, and incubation mechanism 900, in some embodiments of the present invention, the sample analyzer 10 can also perform a retest operation when there is an abnormality in the reaction solution. Specifically, the reaction vessel supply mechanism 800 is also used to output a second reaction vessel, wherein the first reaction vessel 20 and the second reaction vessel can be reaction vessels of the same specifications or reaction vessels of different specifications.
[0061] In this embodiment, the control device is configured to: when it is determined from the first target image that the volume of the first reaction liquid loaded in the first reaction container 20 is abnormal (the specific judgment method can be understood by referring to the aforementioned embodiment), or when it is determined from the first target image that there are bubbles or foreign objects in the first reaction liquid loaded in the first reaction container 20 (the specific judgment method can be understood by referring to the aforementioned embodiment), control the reaction container supply mechanism 800 to output an empty second reaction container; then control the sample distribution mechanism 400 to absorb at least a portion of the sample to be tested from the sample container and distribute all or part of the absorbed sample to be tested into the second reaction container, and control the reagent distribution mechanism 500 to absorb at least a portion of the reagent from the reagent container storage mechanism 600 and distribute all or part of the absorbed reagent into the second reaction container, thereby forming a second reaction liquid in the second reaction container from at least the sample to be tested and the reagent; after the second reaction liquid is prepared, control the incubation mechanism 900 to incubate the second reaction liquid loaded in the second reaction container, and control the measuring mechanism 300 to measure the second reaction liquid loaded in the second reaction container to obtain sample retest data, thus ensuring the accuracy of the detection effect.
[0062] It should be noted that the sample and reagents used to prepare the first reaction solution should be the same as those used to prepare the second reaction solution.
[0063] When the sample analyzer 10 further includes the aforementioned reaction vessel supply mechanism 800, sample dispensing mechanism 400, and incubation mechanism 900, in some embodiments of the present invention, the sample analyzer 10 is an analyzer equipped with a sample introduction mechanism 700. The sample introduction mechanism 700 includes a sample storage mechanism and a sample scheduling mechanism. The sample storage mechanism includes a loading area and a buffer area. Both the loading area and the buffer area are used to support sample racks containing sample containers. Specifically, the loading area is typically used to support sample racks containing sample containers to be aspirated, and the buffer area is typically used to support sample racks containing sample containers that have already been aspirated. The sample scheduling mechanism is used to schedule the sample racks so that sample containers placed on the sample racks are scheduled from the loading area to the aspiration position, and to schedule sample containers placed on the sample racks from the aspiration position to the buffer area. The sample racks can support multiple sample containers arranged in a straight line.
[0064] For example, the sample scheduling mechanism includes a feed track extending along a set direction, with sample suction positions. When a sample rack is located on the feed track, it can be transported by the feed track, allowing sample containers on the sample rack to pass through the suction positions sequentially. Furthermore, the sample scheduling mechanism includes a first transport mechanism for transferring a sample rack containing sample containers to be suctioned from a buffer area to the feed track, and a second transport mechanism for transferring a sample rack containing already suctioned sample containers between the feed track and the buffer area. The first and second transport mechanisms can be pushing mechanisms capable of moving the sample rack or moving units capable of carrying and moving the sample rack. In some specific embodiments, the sample introduction mechanism 700 is also provided with a transport track, allowing the sample rack to enter the loading area from the transport track. The transport tracks of multiple sample analyzers 10 are interconnected, thereby forming an analytical pipeline.
[0065] In this embodiment, the control device is configured to: after the sample dispensing mechanism 400 draws the sample to be tested from the sample container and dispenses it into the first reaction container 20, control the sample scheduling mechanism to schedule the sample rack carrying the sample container to the buffer area for caching. For example, when all or part of the sample containers on the sample rack have been aspirated, the scheduling mechanism schedules the sample rack to the buffer area for caching, thereby waiting for the test results. Based on the test results, it can be further determined whether the sample containers on the sample rack need to be returned for aspiration or removed from the sample analyzer 10.
[0066] The controller is also configured to: when it is determined from the first target image that the volume of the first reaction liquid loaded in the first reaction container 20 is abnormal (the specific judgment method can be understood by referring to the aforementioned embodiments), or when it is determined from the first target image that there are bubbles or foreign objects in the first reaction liquid loaded in the first reaction container 20 (the specific judgment method can be understood by referring to the aforementioned embodiments), control the sample scheduling mechanism to schedule the sample rack of the sample container (hereinafter referred to as "the sample container" for ease of description) carrying the sample to be tested for preparing the first reaction liquid, so that the sample container is rescheduled from the buffer area to the aspiration position; then control the sample dispensing mechanism 400 to re-absorb at least a portion of the sample to be tested from the sample container located at the aspiration position and dispense all or part of the aspirated sample to be tested into the second reaction container, and control the reagent dispensing mechanism 500 to aspirate at least a portion of the reagent from the reagent container storage mechanism 600 and dispense all or part of the aspirated reagent into the second reaction container, so that at least the sample to be tested and the reagent are used to prepare the second reaction liquid in the second reaction container; then control the measuring mechanism 300 to measure the second reaction liquid loaded in the second reaction container after incubation treatment to obtain sample retest data. In some embodiments, the first reaction vessel 20 and the second reaction vessel are reaction vessels of the same specifications. In other embodiments, the first reaction vessel 20 and the second reaction vessel are reaction vessels of different specifications.
[0067] For example, when the feed track transports the sample rack along the set direction and all or part of the sample containers on it have completed sampling, the feed track moves in the opposite direction to output the sample rack. The output sample rack is transferred by the second transport mechanism to the buffer position in the buffer area for buffering. When it is determined that the first reaction liquid made from the sample to be tested from a certain sample container has an abnormal liquid volume or contains bubbles or foreign matter, the second transport mechanism removes the sample container from the buffer area and transfers it to the feed track. The feed track then transports the sample rack along the set direction so that the sample container reaches the sampling position.
[0068] In some embodiments, the aforementioned sample introduction mechanism 700 further includes an unloading area and a third transport mechanism for driving the sample rack from the buffer area to the unloading area. The unloading area is used to place the sample container that has been aspirated by the sample distribution mechanism 400 and measured by the measurement mechanism 300 to realize the recovery of the sample container.
[0069] In this embodiment, the controller is further configured to: when it is determined from the first target image that the volume of the first reaction liquid is not abnormal, and when it is determined from the first target image that there are no bubbles or foreign objects in the first reaction liquid, control the sample scheduling mechanism to schedule the sample rack carrying the sample container (here, the sample container refers to the sample container containing the sample prepared with the first reaction liquid that is not abnormal) so that the sample container placed on the sample rack is scheduled from the buffer area to the unloading area. At this time, the user can take the sample rack from the unloading area, or the sample rack can continue to be transferred from the unloading area to the transport track and transported by the transport track to the sample management module for output.
[0070] Based on the first embodiment, in some embodiments of the present invention, reference is made to Figure 2 The aforementioned "first camera mechanism 100 is used to perform a first shooting action on the first reaction liquid in the first reaction container 20 during the process of transferring the first reaction container 20 containing the measured first reaction liquid from the detection position 101 to the throwing position 102 in the transfer mechanism 200" specifically means that: the first camera mechanism 100 is set close to the detection position 101, and the first camera mechanism 100 performs a first shooting action on the first reaction container 20 containing the measured first reaction liquid located at the detection position 101.
[0071] In other embodiments, reference is made to Figure 3 The aforementioned "first camera mechanism 100 is used to perform a first shooting action on the first reaction liquid in the first reaction container 20 during the process of transferring the first reaction container 20 containing the measured first reaction liquid from the detection position 101, or the cup-throwing position 102, or the transfer mechanism 200" specifically means that: the first camera mechanism 100 is set close to the cup-throwing position 102, and the first camera mechanism 100 performs a first shooting action on the first reaction container 20 containing the measured first reaction liquid located at the cup-throwing position 102.
[0072] In other embodiments, reference is made to Figure 4The sample analyzer 10 also has a shooting position 103, which is set independently of the detection position 101 and the cup-throwing position 102. The aforementioned "first camera mechanism 100 is used to perform a first shooting action on the first reaction liquid in the first reaction container 20 during the process of transferring the first reaction container 20 containing the measured first reaction liquid from the detection position 101 to the cup-throwing position 102 or in the transfer mechanism 200" specifically means that: the first camera mechanism 100 is set close to the shooting position 103, the shooting position 103 is set independently of the detection position 101 and the cup-throwing position 102, the transfer mechanism 200 first transfers the first reaction container 20 containing the measured first reaction liquid from the detection position 101 to the shooting position 103, and the first camera mechanism 100 performs a first shooting action on the first reaction container 20 containing the measured first reaction liquid located at the shooting position 103. After the filming is completed, the first reaction container 20 containing the measured first reaction liquid is transferred from the filming position 103 to the cup-throwing position 102.
[0073] In other embodiments, a first camera mechanism 100 is mounted on a transfer mechanism 200. The first camera mechanism 100 performs a first imaging action on a first reaction container 20 containing a measured first reaction liquid located on the transfer mechanism 200. For example, the transfer mechanism 200 includes a robotic arm and a drive device for moving the robotic arm. In this case, the first camera mechanism 100 is mounted on the robotic arm or the drive device. When the robotic arm grips the first reaction container 20, the first camera mechanism 100 performs the first imaging action. It should be noted that since the first camera mechanism 100 in this embodiment moves synchronously with the robotic arm, after the robotic arm grips the first reaction container 20, the first camera mechanism 100 can perform detection at the detection position 101, the cup-throwing position 102, or any position between the detection position 101 and the cup-throwing position 102.
[0074] Based on the first embodiment, in some embodiments of the present invention, the control device is configured to: obtain the test result of the sample to be tested based on the sample test data obtained by the measuring mechanism 300 measuring the first reaction liquid, and then control the first camera mechanism 100 to perform the first shooting action based on the test result of the sample to be tested. That is, in this embodiment, the abnormal detection of the first reaction liquid needs to be determined based on the test result to determine whether to start. If it is determined based on the test result that there is no problem with the relevant indicators of the sample to be tested, then there is no need to start the abnormal detection process of the first reaction liquid, thereby reducing the detection steps.
[0075] In some specific embodiments, the aforementioned "controlling the first camera mechanism 100 to perform the first shooting action according to the detection result of the sample to be tested" specifically means: when it is determined that the detection result of the sample to be tested is not within the fourth preset range, controlling the first camera mechanism 100 to perform the first shooting action; or, when it is determined that the detection result of the sample to be tested cannot be obtained, controlling the first camera mechanism 100 to perform the first shooting action.
[0076] Based on the first embodiment, in some embodiments of the present invention, the sample analyzer 10 can be a coagulation analyzer. The sample container suitable for the coagulation analyzer has a cap, which can prevent the coagulation factors in the sample from being exposed to air and thus lost. Based on this, the sample analyzer 10 in this embodiment includes a sample needle, which is a puncture needle with a puncture function. The sample needle is used to puncture the cap of the sample container to at least partially penetrate into the sample container and draw up the sample to be tested and dispense it into the first reaction container 20. This allows for sample aspiration while keeping the sample isolated from the outside world.
[0077] Based on the first embodiment, in some embodiments of the present invention, the sample analyzer 10 may be a coagulation analyzer, and the measuring mechanism 300 is correspondingly configured as a photometric component that measures the first reaction liquid in at least a local area loaded in the first reaction container 20 using an optical method. The specific scheme can be understood with reference to the foregoing embodiments. Based on this, in this embodiment, the control device is configured to adjust the wavelength or power of the light beam of the photometric component according to the hemolysis index, lipemia index, or jaundice index of the sample to be tested, thereby ensuring the detection quality.
[0078] The embodiments of the present invention have been described in detail above with reference to the accompanying drawings. However, the present invention is not limited to the above embodiments, and various changes can be made within the scope of knowledge possessed by those skilled in the art without departing from the spirit of the present invention. Furthermore, the embodiments of the present invention and the features thereof can be combined with each other unless otherwise specified.
Claims
1. A sample analyzer, characterized in that, include: A detection position is used to place a first reaction container containing a first reaction solution that has undergone incubation treatment, the first reaction solution being made from at least the sample to be tested and a reagent; A measuring mechanism is used to measure the first reaction liquid loaded in the first reaction container located at the detection position to obtain sample detection data. A transfer mechanism is used to transfer the first reaction container containing the measured first reaction liquid to the cup throwing position, and to throw the first reaction container into the reaction cup recovery mechanism at the cup throwing position. A first camera mechanism is configured to perform a first image capture action on the measured first reaction liquid loaded in the first reaction container at the detection position, at the cup-throwing position, or during the process of the transfer mechanism transferring the first reaction container loaded with the measured first reaction liquid from the detection position to the cup-throwing position. A control device configured to: obtain a first target image based on the image captured by the first camera mechanism performing the first shooting action; and output at least one of the following information based on the first target image: the first target image, a determination result of whether the volume of the first reaction liquid is abnormal, and a determination result of whether there are bubbles or foreign objects in the first reaction liquid. The first target image includes at least an image showing the first reaction liquid in a two-dimensional and / or three-dimensional form, and at least the first target image is used as a basis for determining whether the volume of the first reaction liquid is abnormal and / or as a basis for determining whether the first reaction liquid contains bubbles or foreign matter.
2. The sample analyzer as described in claim 1, characterized in that: The step of outputting at least one of the following information based on the first target image: the first target image, the determination result of whether the volume of the first reaction liquid is abnormal, and the determination result of whether there are bubbles or foreign objects in the first reaction liquid, includes: outputting the first target image; Alternatively, the step of outputting at least one of the following information based on the first target image: the first target image, the volume of the first reaction liquid, a determination result of whether the volume of the first reaction liquid is abnormal, and a determination result of whether there are bubbles or foreign objects in the first reaction liquid, includes: outputting the first target image, and outputting at least one of the determination result of whether the volume of the first reaction liquid is abnormal and the determination result of whether there are bubbles or foreign objects in the first reaction liquid.
3. The sample analyzer as described in claim 1, characterized in that, The first target image is used as at least as a basis for determining whether there is an abnormality in the volume of the first reaction solution, including: The volume of the first reaction liquid in the first reaction container is obtained based on the first target image, and the volume of the first reaction liquid is determined to be abnormal based on whether the volume value is within a first preset range; and / or, Based on the height value of the first reaction liquid loaded in the first reaction container obtained from the first target image, it is determined whether the volume of the first reaction liquid is abnormal based on whether the height value is within a second preset range.
4. The sample analyzer as described in claim 1, characterized in that, Also includes: A sample dispensing mechanism, the sample dispensing mechanism being used to aspirate at least a portion of the test sample from the sample container and dispense all or part of the aspirated test sample into the first reaction container; The second camera mechanism is used to perform a second shooting action on the first reaction container that only contains the sample to be tested before the measuring mechanism measures the first reaction liquid loaded in the first reaction container. The control device is configured to: obtain a second target image based on the image captured by the second shooting action performed by the second camera mechanism; At least the first target image is used as a basis for determining whether the volume of the first reaction liquid is abnormal, including: obtaining the change in the volume of the liquid loaded in the first reaction container based on the second target image and the first target image, and determining whether the volume of the first reaction liquid is abnormal based on whether the change in the volume of the liquid loaded in the first reaction container is within a third preset range. The first camera mechanism and the second camera mechanism are the same institution, or the first camera mechanism is set up independently of the second camera mechanism.
5. The sample analyzer as described in claim 1, characterized in that, The measuring mechanism is constructed as a photometric component that measures the first reaction liquid in at least a local area loaded in the first reaction vessel based on an optical method. At least the first target image is used as a basis for determining whether the first reaction liquid contains bubbles or foreign matter, including: obtaining an image of the first reaction liquid in at least the local area loaded in the first reaction container based on the first target image, and determining whether bubbles or foreign matter exist in the first reaction liquid based on whether the image of the local area contains features that characterize bubbles or foreign matter.
6. The sample analyzer as described in claim 1, characterized in that, The first target image is used as a basis for determining whether the first reaction solution contains bubbles or foreign matter, including: extracting the first target image to obtain a target index for characterizing the light spot, and determining whether the first reaction solution contains bubbles or foreign matter based on whether the target index is greater than a preset index; and / or, Extract target features from the first target image, and determine whether the first reaction liquid contains bubbles or foreign matter based on whether the similarity between the target features and preset features is greater than a preset threshold.
7. The sample analyzer according to any one of claims 1 to 3, 5, or 6, characterized in that, Also includes: A reaction vessel supply mechanism, wherein the reaction vessel supply mechanism is used to output the first reaction vessel; A sample dispensing mechanism, the sample dispensing mechanism being used to aspirate at least a portion of the sample to be tested from a sample container and dispense all or part of the aspirated sample to be tested into the first reaction container; A reagent dispensing mechanism is used to draw at least a portion of the reagent from a reagent container from a reagent container storage mechanism and dispense all or part of the drawn reagent into a first reaction container, wherein the first reaction solution is prepared in the first reaction container from at least the test sample and the reagent; An incubation apparatus, wherein the incubation apparatus is used to perform the incubation treatment on the first reaction liquid loaded in the first reaction vessel; The sample dispensing mechanism and the reagent dispensing mechanism are the same mechanism, or the sample dispensing mechanism is set up independently of the reagent dispensing mechanism.
8. The sample analyzer as described in claim 7, characterized in that, The reaction vessel supply mechanism is also used to output a second reaction vessel; The control device is configured to: when it is determined from the first target image that the volume of the first reaction liquid loaded in the first reaction container is abnormal, or when it is determined from the first target image that there are bubbles or foreign objects in the first reaction liquid loaded in the first reaction container, control the reaction container supply mechanism to output the second reaction container, control the sample dispensing mechanism to draw at least a portion of the sample to be tested from the sample container and dispense all or part of the drawn sample to the second reaction container, control the reagent dispensing mechanism to draw at least a portion of the reagent from the reagent container from the reagent container storage mechanism and dispense all or part of the drawn reagent to the second reaction container, wherein the second reaction liquid is prepared in the second reaction container at least by the sample to be tested and the reagent, control the incubation mechanism to incubate the second reaction liquid loaded in the second reaction container, and control the measuring mechanism to measure the second reaction liquid loaded in the second reaction container to obtain sample retest data; The first reaction vessel and the second reaction vessel are reaction vessels of the same specifications, or the first reaction vessel and the second reaction vessel are reaction vessels of different specifications.
9. The sample analyzer as described in claim 7, characterized in that, include: A sample storage mechanism, comprising a loading area and a buffer area, both of which are used to support sample racks containing sample containers; A sample scheduling mechanism is used to schedule sample racks so that sample containers placed on the sample racks are scheduled from the loading area to the sampling position, and so that sample containers placed on the sample racks are scheduled from the sampling position to the buffer area. The control device is configured to: after the sample dispensing mechanism draws the sample to be tested from the sample container and dispenses it into the first reaction container, control the sample scheduling mechanism to schedule the sample rack carrying the sample container to the buffer area for buffering. The controller is further configured to: when it is determined from the first target image that the volume of the first reaction solution is abnormal, and / or when it is determined from the first target image that there are bubbles or foreign matter in the first reaction solution, control the sample scheduling mechanism to schedule the sample rack carrying the sample container for preparing the first reaction solution, so that the sample container is rescheduled from the buffer area to the aspiration position; control the sample dispensing mechanism to re-absorb at least a portion of the sample to be tested from the sample container located at the aspiration position and dispense all or part of the aspirated sample to be tested into the second reaction container; control the reagent dispensing mechanism to aspirate at least a portion of the reagent from the reagent container from the reagent container storage mechanism and dispense all or part of the aspirated reagent into the second reaction container, wherein the second reaction solution is prepared in the second reaction container at least by the sample to be tested and the reagent; and control the measuring mechanism to measure the second reaction solution loaded in the second reaction container after incubation treatment to obtain sample retest data. The first reaction vessel and the second reaction vessel are reaction vessels of the same specifications, or the first reaction vessel and the second reaction vessel are reaction vessels of different specifications.
10. The sample analyzer as described in claim 9, characterized in that, The sample storage mechanism further includes an unloading area, which is used to place the sample containers that have been aspirated by the sample distribution mechanism and measured by the measuring mechanism to realize the recovery of the sample containers. The controller is also configured to: when it is determined from the first target image that there is no abnormality in the volume of the first reaction liquid, and when it is determined from the first target image that there are no bubbles or foreign objects in the first reaction liquid, control the sample scheduling mechanism to schedule the sample rack so that the sample containers placed on the sample rack are scheduled from the buffer area to the unloading area.
11. The sample analyzer according to any one of claims 1 to 6, characterized in that, The first camera mechanism is used to perform a first imaging action on the first reaction liquid in the first reaction container during the process of transferring the first reaction container containing the measured first reaction liquid from the detection position to the throwing position in the transfer mechanism, including: The first camera is positioned close to the detection position, and the first camera performs a first shooting action on the first reaction container located at the detection position, which is loaded with the measured first reaction liquid. Alternatively, the first camera is positioned close to the cup-throwing position, and the first camera performs a first shooting action on the first reaction container located at the cup-throwing position, which contains the measured first reaction liquid. Alternatively, the first camera mechanism is positioned close to the shooting position, which is independent of the detection position and the cup-throwing position. The transfer mechanism transfers the first reaction container containing the measured first reaction liquid from the detection position to the shooting position. The first camera mechanism performs a first shooting action on the first reaction container containing the measured first reaction liquid located at the shooting position. Alternatively, the first camera mechanism is mounted on the transfer mechanism, and the first camera mechanism performs a first shooting action on the first reaction container located on the transfer mechanism, which contains the measured first reaction liquid.
12. The sample analyzer according to any one of claims 1 to 6, characterized in that, The control device is configured to: obtain the test result of the sample to be tested based on the sample test data obtained by the measuring mechanism measuring the first reaction liquid, and control the first camera mechanism to perform the first shooting action based on the test result of the sample to be tested.
13. The sample analyzer as described in claim 12, characterized in that, The step of controlling the first camera mechanism to perform the first shooting action based on the detection result of the sample to be tested includes: when it is determined that the detection result of the sample to be tested is not within a fourth preset range, controlling the first camera mechanism to perform the first shooting action; or, If it is determined that the detection result of the sample to be tested cannot be obtained, the first camera mechanism is controlled to perform the first shooting action.
14. The sample analyzer as described in claim 7, characterized in that, The sample container has a cap, and the sample dispensing mechanism includes a sample needle, which is a puncture needle with a puncture function. The sample needle is used to puncture the cap of the sample container to at least partially penetrate the sample container and draw up the sample to be tested and dispense it into the first reaction container.
15. The sample analyzer as described in claim 1, characterized in that, The measuring mechanism is constructed as a photometric component that measures the first reaction liquid in at least a local area loaded in the first reaction container using an optical method. The control device is configured to adjust the wavelength or power of the light beam of the photometric component according to the hemolysis index, lipemia index, or jaundice index of the sample to be tested.