A piezoelectric composite material for enhancing nano-enzyme activity, a preparation method thereof, and an antibacterial application thereof
By in-situ growing cobalt-doped molybdenum disulfide on bismuth titanate nanosheets, a piezoelectrically enhanced nanozyme system was constructed, which solved the problem of insufficient endogenous hydrogen peroxide in nanozymes and achieved a highly efficient antibacterial effect.
CN122229040APending Publication Date: 2026-06-19BEIJING INSTITUTE OF TECHNOLOGY (ZHUHAI)
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Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- BEIJING INSTITUTE OF TECHNOLOGY (ZHUHAI)
- Filing Date
- 2026-05-22
- Publication Date
- 2026-06-19
AI Technical Summary
Technical Problem
Existing nanozymes have low catalytic activity due to insufficient endogenous hydrogen peroxide, making them difficult to effectively kill bacteria. Furthermore, there are no reports of piezoelectric effects being combined with nanozyme systems.
Method used
By in-situ growing cobalt-doped molybdenum disulfide on the surface of bismuth titanate nanosheets, a piezoelectric-enhanced nanozyme system was constructed. The piezoelectric effect was used to promote electron transfer and hole catalysis to generate hydrogen peroxide from water, thereby enhancing catalytic activity.
Benefits of technology
It achieved highly effective antibacterial effects against Staphylococcus aureus and Escherichia coli, with bactericidal rates of 98.39% and 99.95%, respectively.
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Abstract
This invention belongs to the field of biomedical materials technology, and relates to a piezoelectrically enhanced nanoenzyme composite material, its preparation method, and its antibacterial application. Cobalt-doped molybdenum disulfide is grown in situ on the surface of bismuth titanate nanosheets to obtain a BTO@Co-MoS2 composite material. This composite material exhibits a piezoelectric effect under pressure stimulation. Electrons, under the influence of the built-in electric field at the BTO@Co-MoS2 interface, promote the self-cycling of the molybdenum disulfide redox pair, thereby improving the catalytic activity of halogen-like peroxidases. Simultaneously, the piezoelectric catalysis of hydrogen peroxide generation alleviates the problem of insufficient endogenous hydrogen peroxide. In antibacterial applications, the piezoelectrically enhanced nanoenzyme composite material prepared by this invention achieves bactericidal rates of 98.39% and 99.95% against Staphylococcus aureus and Escherichia coli, respectively.
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