Application of platelet exosome in treating diabetes mellitus wound healing
By preparing and applying platelet exosome products, the healing problem of diabetic foot ulcers has been solved, achieving efficient wound healing and repair, and enhancing the treatment effect of diabetic foot.
Patent Information
- Application Number
- CN202610246686.5
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2026-03-02
- Publication Date
- 2026-06-19
AI Technical Summary
Existing treatments have limited effectiveness in healing chronic and refractory diabetic foot ulcers, and there is a lack of highly efficient and targeted biological therapies. The mechanism of action of platelet exosomes in the complex pathological microenvironment of diabetic foot remains unclear.
Develop products based on platelet exosomes for the prevention and treatment of diabetic foot, promote wound healing, enhance wound angiogenesis, regulate inflammatory response, inhibit pro-inflammatory factor expression, increase MMP-2 expression, and decrease MMP-9 expression, by preparing and applying effective amounts of platelet exosome products.
It significantly promotes wound healing in diabetic mice, shortens healing time, enhances granulation tissue growth and angiogenesis, regulates wound inflammatory response, reduces infection risk, and improves collagen synthesis capacity.