Use of allulose or erythritol in improving gut microbiota and medicine

By applying a combination of allulose and erythritol, the colonic bacterial communities of Trichophytonceae and Euglenophyceae were increased, which solved the problem of the impact of high sugar intake on the gut microbiota, especially the problem of insufficient butyrate production, and achieved the effects of improving gut health and preventing diseases.

CN122249204APending Publication Date: 2026-06-19TATE & LYLE SOLUTIONS USA LLC

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
TATE & LYLE SOLUTIONS USA LLC
Filing Date
2024-10-18
Publication Date
2026-06-19

AI Technical Summary

Technical Problem

Existing technologies have not effectively addressed the impact of high sugar intake on the gut microbiota, particularly the problem of insufficient butyrate production in patients with type 2 diabetes. Furthermore, current probiotic products do not perform well in surviving and competing in the gut environment.

Method used

A combination of allulose and erythritol, administered orally, increases the colonic bacterial community of Trichophyton and Eurybacterium species, promoting the production of short-chain fatty acids.

🎯Benefits of technology

It increases the number of beneficial bacteria in the gut, enhances butyrate production, improves the health of the gut microbiota, and has potential disease prevention and treatment effects.

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Abstract

Methods for improving the gut microbiota of a subject, increasing one or more bacterial communities belonging to the Helicobacterium or Euglobulaceae families in their colonic flora, for the prevention, treatment, or relief of disease, and for increasing the level of short-chain fatty acids in the colon, comprising administering to the subject a composition containing allulose, erythritol, or a combination thereof. The composition used in the above methods comprises allulose, erythritol, or a combination thereof. The composition comprises allulose, erythritol, or a combination thereof, and one or more colonic bacterial communities from the Helicobacterium or Euglobulaceae families.
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