A protein having anti-inflammatory activity and a preparation method and application thereof
By extracting and purifying anti-inflammatory proteins from ginseng powder, the problem of long-term side effects of existing anti-inflammatory drugs has been solved, providing a low-toxicity and highly effective anti-inflammatory solution. This solution is suitable for preparing anti-inflammatory drugs and regulating cell function in vitro to inhibit inflammatory responses.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- GUANGDONG MODERN HANFANG TECH CO LTD
- Filing Date
- 2026-05-27
- Publication Date
- 2026-06-23
AI Technical Summary
Existing steroidal anti-inflammatory drugs (SAIDs) and nonsteroidal anti-inflammatory drugs (NSAIDs) have side effects with long-term use, such as disorders of glucose, lipid, water and electrolyte metabolism, gastrointestinal damage and cardiovascular disease risk, which limit their use in chronic inflammation, and some patients have developed dose-escalation resistance.
A protein with anti-inflammatory activity was extracted and purified from ginseng powder. The protein was prepared by extraction with 80-100% ethanol and elution with dextran gel column. It was used to prepare anti-inflammatory drugs. The protein was also used to regulate cell function in vitro, inhibit the expression of pro-inflammatory cytokines, oxidative stress response and regulate FOXO signaling pathway genes.
This protein can significantly inhibit neutrophil aggregation, reduce reactive oxygen species levels, suppress oxidative stress response and pro-inflammatory cytokine expression, providing a low-toxicity, highly effective anti-inflammatory solution suitable for long-term use.
Smart Images
Figure CN122255207A_ABST