sample analyser
By setting up a first area in the sample analyzer to place waste and using a drive unit and a scheduling robot to close the opening, the problem of waste contaminating other areas is solved, thus achieving higher accuracy in test results and lower equipment costs.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- SHENZHEN MINDRAY BIO MEDICAL ELECTRONICS CO LTD
- Filing Date
- 2025-12-22
- Publication Date
- 2026-06-23
AI Technical Summary
In existing sample analyzers, the abandoned area remains connected to other areas, leading to aerosol diffusion and contamination, which affects the accuracy of the test results.
Design a sample analyzer comprising a housing module, an extraction module, an amplification and detection module, and a scheduling mechanism. By setting up a first area for placing waste and using a first compartment door to close the first opening, combined with a drive unit and a scheduling robot, the waste can be transferred and isolated.
It effectively improved the problem of waste pollution to other areas, ensured the accuracy of test results, reduced equipment costs, and reduced volume.
Smart Images

Figure CN122256132A_ABST
Abstract
Description
Technical Field
[0001] This invention relates to the field of medical device technology, and in particular to a sample analyzer. Background Technology
[0002] For analytical equipment such as automated molecular diagnostic testing devices, waste is generated during the testing process. This waste includes amplification containers and extraction containers that have contained nucleic acid extraction solutions. This waste is initially collected in the waste area within the sample analyzer for subsequent cleaning. In related technologies, the waste area remains connected to other areas within the sample analyzer (such as the sample area and the consumables area), posing a risk of aerosol diffusion and contamination, which can affect the test results. Summary of the Invention
[0003] This invention aims to at least solve one of the technical problems existing in the prior art. To this end, this invention proposes a sample analyzer that can improve the problem of contamination of other areas of the sample analyzer by waste in a waste area.
[0004] The sample analyzer according to the first embodiment of the present invention includes a housing module, an extraction module, an amplification and detection module, and a scheduling mechanism. The extraction module is used to extract nucleic acids from liquid containing at least the sample in the extraction container to obtain a nucleic acid extract solution; The amplification and detection module is used to amplify and detect a liquid containing at least the nucleic acid extract placed in an amplification container. The amplification container includes a container body for containing the liquid containing at least the nucleic acid extract, and a container cap for sealing the container body. The housing module includes a housing and a first door. The housing has a first region, a second region, and a first opening connecting the first region and the second region. The second region is used to accommodate the extraction module and the amplification detection module. The first region is used to store a first waste from the amplification detection module or a second waste from the extraction module. The first waste includes the amplification container, the container body separated from the container cap, or the container cap separated from the container body. The second waste includes the extraction container. The first door is movable relative to the housing to switch between an open position and a closed position. When the first door is in the open position, the first opening is open. When the first door is in the closed position, the first opening is closed. The scheduling mechanism includes a drive unit and a scheduling robot connected to the drive unit. When the first compartment door is in the open position, the drive unit is configured to drive the scheduling robot to transfer the first waste or the second waste to the first area.
[0005] The sample analyzer according to embodiments of the present invention has at least the following beneficial effects: This embodiment effectively improves the problem of waste in the first area contaminating other areas by setting up a first area for placing waste and sealing the first opening of the first area with a first compartment door, which helps to ensure the accuracy of the test results.
[0006] In other embodiments of the present invention, the drive unit is further configured to: drive the first compartment door from the closed position to the open position during the process of driving the dispatching robot to transfer the first waste or the second waste to the first area.
[0007] In other embodiments of the invention, the scheduling mechanism further includes a driving component; The drive unit drives the first compartment door from the closed position to the open position, including: the drive unit drives the push component to abut against the first compartment door, and after the push component abuts against the first compartment door, it continues to drive the push component to push the first compartment door from the closed position to the open position.
[0008] In other embodiments of the present invention, the driving unit includes a vertical driving component, a first horizontal driving component, and a second horizontal driving component. The vertical driving component is used to drive the scheduling robot to move in a vertical direction. The first horizontal driving component is used to drive the scheduling robot to move in a first horizontal direction. The second horizontal driving component is used to drive the scheduling robot to move in a second horizontal direction. The first horizontal direction and the second horizontal direction intersect. The scheduling robot is configured to transfer the first waste or the second waste to the first area by moving along the vertical direction, the first horizontal direction, and the second horizontal direction. Wherein, the driving unit continues to drive the pushing component to push the first compartment door from the closed position to the open position after the pushing component abuts against the first compartment door, including: The first horizontal drive component drives the push component to move along the first horizontal direction to push the first compartment door from the closed position to the open position; Alternatively, the second horizontal drive component drives the push component to move along the second horizontal direction to push the first compartment door from the closed position to the open position; Alternatively, the vertical drive component drives the push component to move along the vertical direction to push the first compartment door from the closed position to the open position; Alternatively, the drive unit includes a vertical drive component and a first horizontal drive component, the vertical drive component being used to drive the scheduling robot to move in a vertical direction, and the first horizontal drive component being used to drive the scheduling robot to move in a first horizontal direction, the scheduling robot being configured to transfer the first waste or the second waste to the first area by moving in the vertical direction and the first horizontal direction; Wherein, the driving unit continues to drive the pushing component to push the first compartment door from the closed position to the open position after the pushing component abuts against the first compartment door, including: The first horizontal drive component drives the push component to move along the first horizontal direction to push the first compartment door from the closed position to the open position; Alternatively, the vertical drive component drives the push component to move along the vertical direction to push the first compartment door from the closed position to the open position.
[0009] In other embodiments of the present invention, the pushing component and the scheduling robot are the same component; or, the pushing component is a different component independent of the scheduling robot, and the pushing component is connected to the scheduling robot to move synchronously with the scheduling robot; or, the pushing component is a different component independent of the scheduling robot, and the pushing component is connected to the drive unit.
[0010] In other embodiments of the present invention, the drive unit drives the scheduling robot to move to transfer the first waste or the second waste to the first area, including: the drive unit drives the scheduling robot to move to a first position and simultaneously drives the push component to push the first compartment door from the closed position to the open position, and when the first compartment door is in the open position, drives the scheduling robot to move from the first position to a second position and release the first waste or the second waste, so that the first waste or the second waste falls into the first area; Wherein, the second position is closer to the first opening than the first position, and during the process of the scheduling robot moving from the first position to the second position, the pushing component remains in contact with the first compartment door so that the first compartment door remains in the open position; Preferably, the pushing component is a different component independent of the scheduling robot, and the pushing component moves synchronously with the scheduling robot; or, the pushing component and the scheduling robot are the same component. During the process of the scheduling robot moving from the first position to the second position, the pushing component moves synchronously relative to the first compartment door, and the direction of movement of the pushing component relative to the first compartment door intersects with the direction of pushing the pushing component to push the first compartment door; More preferably, one of the pushing component and the first compartment door is provided with a first roller, and the other is provided with an abutting surface. The pushing component and the first compartment door are kept in contact with the abutting surface through the first roller, and the first roller is configured to roll relative to the abutting surface during the movement of the pushing component relative to the first compartment door.
[0011] In other embodiments of the present invention, the drive unit drives the scheduling robot to move to transfer the first waste or the second waste to the first area, including: the drive unit drives the scheduling robot to move to a first position and simultaneously drives the push component to push the first compartment door from the closed position to the open position; and when the first compartment door is in the open position, the drive unit drives the scheduling robot to release the first waste or the second waste at the first position so that the first waste or the second waste falls into the first area.
[0012] In other embodiments of the present invention, the housing module further includes a first elastic element disposed between the housing and the first compartment door, configured to drive the first compartment door from the open position to the closed position after the pushing component separates from the first compartment door.
[0013] In other embodiments of the present invention, the first compartment door is configured to be movable relative to the housing in both a vertical and horizontal direction, the housing including a first sealing surface, the first compartment door having a second sealing surface, the housing module further including a first sealing member, the first sealing member being connected to at least one of the first sealing surface and the second sealing surface, and abutting against the other when the first compartment door is in the closed position to seal the first opening; After the pushing component abuts against the first compartment door, the driving unit continues to drive the pushing component to push the first compartment door from the closed position to the open position, including: the driving unit drives the pushing component to push the first compartment door from the closed position to the first set position or pushes it a first set distance along the first direction, and then pushes the first compartment door to the open position along the second direction, wherein the first angle between the first direction and the first sealing surface is greater than the second angle between the second direction and the first sealing surface, the first angle is greater than 0 and less than or equal to 90°, and the second angle is greater than or equal to 0 and less than or equal to 90°.
[0014] In other embodiments of the present invention, the housing module further includes a guiding component, the guiding component having a first trajectory surface and a second trajectory surface, the second trajectory surface and the first trajectory surface being disposed along a second direction, the first trajectory surface being parallel to the first direction, and the second trajectory surface being parallel to the second direction; Specifically, during the process where the drive unit drives the push assembly to push the first compartment door from the closed position to the first set position or push it a first set distance along the first direction, the first compartment door abuts against the first track surface and moves relative to the first track surface; during the process where the drive unit drives the push assembly to push the first compartment door to the open position along the second direction, the first compartment door abuts against the second track surface and moves relative to the second track surface. Preferably, the first compartment door has a third trajectory surface. During the process of the pushing component pushing the first compartment door from the closed position to the open position, the drive unit is configured to drive the pushing component to move synchronously with the scheduling robot in the vertical direction, and the pushing component abuts against the third trajectory surface and moves relative to the third trajectory surface, so that the first compartment door moves relative to the guide component from the first trajectory surface to the second trajectory surface. When the first compartment door is in the open position, the dispatching robot is in the first position, wherein: The drive unit is also configured to drive the scheduling robot to release the first waste or the second waste at the first position; Alternatively, the drive unit is further configured to drive the pushing component to move synchronously with the scheduling robot in a vertical direction until the scheduling robot is in a second position, and drive the scheduling robot to release the first waste or the second waste in the second position so that the first waste or the second waste falls into the first area, the second position being lower than the first position; The pushing component has a fourth trajectory surface. During the process of the scheduling robot moving from the first position to the second position, the pushing component separates from the third trajectory surface. After the pushing component separates from the third trajectory surface, the fourth trajectory surface abuts against the first compartment door and moves relative to the first compartment door so that the first compartment door remains in the open position. Preferably, the first door has a third trajectory surface, and the pushing component has a fourth and a fifth trajectory surface. The fifth trajectory surface is connected to the upper side of the fourth trajectory surface. During the process of the pushing component pushing the first door from the closed position to the open position, the drive unit is configured to drive the pushing component and the scheduling robot to move synchronously in the vertical direction so that the pushing component sequentially performs a first stroke, a second stroke, and a third stroke. During the first stroke, the pushing component abuts against the third trajectory surface and moves relative to the third trajectory surface, so that the first door moves relative to the guide component from the first trajectory surface. The push component moves to the second trajectory surface; during the second stroke of the push component, the push component separates from the third trajectory surface. After the push component separates from the third trajectory surface, the fourth trajectory surface abuts against the first compartment door and moves relative to the first compartment door to keep the first compartment door in its current position; during the third stroke of the push component, the fourth trajectory surface separates from the first compartment door. After the fourth trajectory surface separates from the first compartment door, the fifth trajectory surface abuts against the first compartment door and moves relative to the first compartment door to push the first compartment door to move relative to the second trajectory surface along the second direction to the open position; When the first compartment door is in the open position, the dispatching robot is in the first position, wherein: The drive unit is also configured to drive the scheduling robot to release the first waste or the second waste at the first position; Alternatively, the drive unit is further configured to drive the pushing component to move synchronously with the scheduling robot in a vertical direction until the scheduling robot is in a second position, and drive the scheduling robot to release the first waste or the second waste in the second position so that the first waste or the second waste falls into the first area, the second position being lower than the first position; The pushing component has a sixth trajectory surface connected to the upper side of the fifth trajectory surface. During the process of the scheduling robot moving from the first position to the second position, the fifth trajectory surface separates from the first door. After the fifth trajectory surface separates from the first door, the sixth trajectory surface abuts against the first door and moves relative to the first door so that the first door remains in the open position.
[0015] In other embodiments of the present invention, the first sealing surface and the second sealing surface are arranged parallel to each other and are both inclined relative to the horizontal direction, wherein the first direction is perpendicular to the first sealing surface, and / or the second direction is parallel to the horizontal direction; And / or, the housing module further includes a first sliding assembly, a second sliding assembly, and a second connecting seat, wherein the first compartment door is connected to the second connecting seat via the first sliding assembly, and the second connecting seat is connected to the housing via the second sliding assembly, wherein the first compartment door is slidable relative to the second connecting seat in the horizontal direction, and the second connecting seat is slidable relative to the housing in the vertical direction; or, the first compartment door is slidable relative to the second connecting seat in the vertical direction, and the second connecting seat is slidable relative to the housing in the horizontal direction. The housing module further includes a second elastic element and a third elastic element. The second elastic element is connected between the first compartment door and the second connecting seat, and the third elastic element is connected between the second connecting seat and the housing. The second elastic element and the third elastic element are configured to drive the first compartment door to reset to the closed position after the pushing component disengages from the first compartment door.
[0016] In other embodiments of the present invention, the first compartment door is slidably connected to the housing, wherein the driving unit drives the first compartment door from the closed position to the open position, including: driving the first compartment door to move horizontally from the closed position to the open position; Preferably, the housing includes a compartment, the compartment includes a main body and a first sealing portion protruding from the end face of the main body, the main body has a first region, the first sealing portion has a first sealing surface and a first opening, the first compartment door has a second sealing surface, and along the moving direction of the first compartment door from the open position to the closed position, the distance from the first sealing surface to the end face and the distance from the second sealing surface to the end face both increase; The housing module further includes a first seal, which is connected to at least one of the first sealing surface and the second sealing surface, and abuts against the other when the first door is in the closed position to seal the first opening.
[0017] In other embodiments of the present invention, the first compartment door is rotatably connected to the housing, and the rotation axes of the two are parallel to the horizontal or vertical direction. The driving unit drives the first compartment door from the closed position to the open position, including driving the first compartment door to rotate from the closed position to the open position.
[0018] In other embodiments of the present invention, the sample analyzer further includes a first storage device located in the first area for storing the first waste and the second waste, the first storage device having an opening facing the first opening.
[0019] In other embodiments of the present invention, the housing further includes a second opening communicating with the first region and the external space of the housing. The housing module further includes a second door that is movable relative to the housing to open or close the second opening. When the second door opens the second opening, the first storage device can be moved out of the first region through the second opening. Preferably, the housing module further includes a second seal, which is connected to at least one of the housing and the second compartment door, and abuts against the other to seal the second opening when the second compartment door closes the second opening.
[0020] In other embodiments of the present invention, the sample analyzer includes a second storage device and a sealing cap, the second storage device having a receiving cavity for storing waste liquid, and the sealing cap being sealed to the second storage device to close the receiving cavity; The sample analyzer also includes a waste liquid needle and a waste liquid pipeline. The waste liquid needle is sealed to the sealing cap through the waste liquid pipeline. The waste liquid needle is used to draw waste liquid from the amplification container and transport the waste liquid to the second storage device through the waste liquid pipeline. Preferably, the second storage device is located within the first area; Preferably, the sealing cap is detachably connected to the second storage device.
[0021] In other embodiments of the invention, the housing includes a compartment, the first region being formed inside the compartment to separate the first region from the second region, the compartment having the first opening.
[0022] In other embodiments of the present invention, the second region further includes a sample area, and the sample analyzer further includes a sample module. The sample module is used to carry a sample container holding a biological sample to be extracted. The sample module is located in the sample area. When the first door is in the closed position, the first region is not connected to the sample area. And / or, the second region further includes an extraction area, the extraction module being located in the extraction area, and when the first compartment door is in the closed position, the first region and the extraction area are not connected; And / or, the second region further includes an amplification region, the amplification detection module is located in the amplification region, and when the first door is in the closed position, the first region is not connected to the amplification region; And / or, the second area further includes a consumables area, and the sample analyzer further includes a first consumables supply device, a second consumables supply device, and a reagent supply device. The first consumables supply device is at least used to provide an extraction container, the second consumables supply device is at least used to provide the amplification container, and the reagent supply device is used to supply reagents. At least one of the first consumables supply device, the second consumables supply device, and the reagent supply device is located within the consumables area. When the first compartment door is in the closed position, the first area is not connected to the consumables area.
[0023] In other embodiments of the present invention, the first region includes a first sub-region and a second sub-region that are independently set, both of which have the first opening. The driving unit is configured to drive the scheduling robot to transfer the first waste from the amplification detection module to the first sub-region, or to transfer the second waste from the extraction module to the second sub-region.
[0024] Additional aspects and advantages of the invention will be set forth in part in the description which follows, and in part will be obvious from the description, or may be learned by practice of the invention. Attached Figure Description
[0025] The present invention will be further described below with reference to the accompanying drawings and embodiments, wherein: Figure 1 This is a schematic diagram of the sample analyzer modules in an embodiment of the present invention; Figure 2 This is a three-dimensional schematic diagram of the housing and scheduling mechanism in an embodiment of the present invention, showing a portion of the structure of the housing; Figure 3 for Figure 2 Side view of the middle shell and scheduling mechanism along the Y-axis, showing part of the shell structure; Figure 4 for Figure 2 Side view of the middle shell and scheduling mechanism along the X-axis, showing part of the shell structure; Figure 5 for Figure 2 A three-dimensional schematic diagram of the inner shell, showing part of the shell's structure; Figure 6 for Figure 5 A three-dimensional schematic diagram of the first compartment door and elastic element hidden in the middle shell, showing part of the shell structure; Figure 7 for Figure 5 A side view of the inner shell, showing part of the shell's structure; Figure 8This is a perspective view of the housing and scheduling mechanism in another embodiment of the present invention, showing a portion of the structure of the housing; Figure 9 for Figure 8 A side view of the inner shell, showing part of the shell's structure; Figure 10 for Figure 8 A front view of the first compartment door and the pushing component, showing the movement steps of the first compartment door along the first track surface and the second track surface; Figure 11 for Figure 8 A three-dimensional schematic diagram of the middle-drive component moving to the end along the third trajectory plane; Figure 12 for Figure 8 A three-dimensional schematic diagram of the first warehouse door moving to the end along the fourth trajectory plane; Figure 13 for Figure 8 A three-dimensional schematic diagram of the first warehouse door moving along the sixth trajectory plane; Figure 14 for Figure 8 The figure shows a front view of the first compartment door and the pushing assembly, illustrating the movement steps of the first compartment door along the third, fourth, and fifth trajectory surfaces.
[0026] Figure label: Sample Analyzer 1; Amplification detection module 10, extraction module 20, sample module 30, reagent supply device 40, and first consumable supply device 50; The components include: housing module 100, compartment body 110, first opening 111, main body 112, first sealing part 113, first sealing surface 114, first compartment door 120, first roller 121, second sealing surface 122, door body 123, first connecting seat 124, third track surface 125, second roller 126, third roller 127, compartment door track plate 128, first elastic element 130, first sealing element 140, guide component 150, first track surface 151, second track surface 152, first sliding assembly 160, second sliding assembly 170, second connecting seat 180, second elastic element 190, and third elastic element 1100. The system includes a scheduling mechanism 200, a drive unit 210, a first horizontal drive component 211, a second horizontal drive component 212, a vertical drive component 213, an opening and closing drive component 214, a scheduling robot arm 220, a pushing component 230, a contact surface 231, a pushing seat 232, a fourth trajectory surface 233, a fifth trajectory surface 234, a sixth trajectory surface 235, and a fourth roller 236.
[0027] First region 101, first sub-region 1011, second sub-region 1012; Second area 102, sample area 1021, extraction area 1022, amplification area 1023, consumables area 1024. Detailed Implementation
[0028] Embodiments of the present invention are described in detail below. Examples of these embodiments are shown in the accompanying drawings, wherein the same or similar reference numerals denote the same or similar elements or elements having the same or similar functions throughout. The embodiments described below with reference to the accompanying drawings are exemplary and are only used to explain the present invention, and should not be construed as limiting the present invention.
[0029] In the description of this invention, it should be understood that the orientation descriptions, such as up, down, front, back, left, right, etc., are based on the orientation or positional relationship shown in the accompanying drawings. They are only for the convenience of describing this invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limiting this invention.
[0030] In the description of this invention, "several" means one or more, "multiple" means two or more, "greater than," "less than," and "exceeding" are understood to exclude the stated number, while "above," "below," and "within" are understood to include the stated number. The use of "first" and "second" in the description is merely for distinguishing technical features and should not be construed as indicating or implying relative importance, or implicitly indicating the number of indicated technical features, or implicitly indicating the order of the indicated technical features.
[0031] In the description of this invention, unless otherwise explicitly defined, terms such as "set up," "install," and "connect" should be interpreted broadly, and those skilled in the art can reasonably determine the specific meaning of the above terms in this invention in conjunction with the specific content of the technical solution.
[0032] In the description of this invention, the terms "one embodiment," "some embodiments," "illustrative embodiment," "example," "specific example," or "some examples," etc., refer to specific features, structures, materials, or characteristics described in connection with that embodiment or example, which are included in at least one embodiment or example of the invention. In this specification, the illustrative expressions of the above terms do not necessarily refer to the same embodiment or example. Furthermore, the specific features, structures, materials, or characteristics described may be combined in any suitable manner in one or more embodiments or examples.
[0033] As mentioned earlier, the first compartment door in related technologies requires a separate drive module, which has disadvantages such as high cost and bulky spatial structure. Based on this, this invention proposes a sample analyzer 1 that can reduce equipment cost and size. The following description, in conjunction with the accompanying drawings and specific embodiments, will illustrate this.
[0034] Reference Figure 1 The diagram illustrates the layout of a sample analyzer in an embodiment of the present invention. It mainly includes an amplification and detection module 10, which amplifies and detects nucleic acids extracted from biological samples. For example, polymerase chain reaction (PCR) technology can be used for amplification. This technology typically amplifies nucleic acid samples extracted from biological samples by cyclically raising and lowering the temperature of the liquid within the amplification container, thereby significantly increasing the amount of nucleic acid sample in a short time. Of course, the technology for amplifying nucleic acids is not limited to PCR; loop-mediated isothermal amplification (LAMP) and isothermal chimeric primer-initiated amplification (ICAN) methods can also be used. The amplification container is mainly used to hold the nucleic acid extraction solution for the amplification reaction; that is, the amplification container provides the amplification reaction site for the nucleic acid extraction solution. The sample to be amplified held in the amplification container is the nucleic acid extracted from the biological sample. The amplification container is also used to hold the amplified nucleic acid obtained after the amplification reaction is completed, for detection by the amplification and detection module 10. The amplification container applicable to this embodiment includes a container body and a container cap. The container body is used to contain the sample, and the container cap can be connected to the container body to close the container body.
[0035] In other embodiments, the sample analyzer 1 further includes functional modules such as an extraction module 20, a sample module 30, a reagent supply device 40, a first consumable supply device 50, and a second consumable supply device. The extraction module 20 is used to extract nucleic acids from the liquid containing at least the sample in the extraction container to obtain a nucleic acid extract. After the obtained nucleic acid extract is transferred from the extraction container to the amplification container, it is amplified and tested by the aforementioned amplification and detection module 10. The sample module 30 is used to hold the sample to be tested. The reagent supply device 40 is used to hold the reagents for testing. The reagents for testing include at least magnetic bead reagents, lysis buffer, elution buffer, silicone oil, and PCR reagents. The first consumable supply device 50 is used to supply the extraction container, and the second consumable supply device is used to supply the amplification container. The extraction container applicable to this embodiment can be an extraction strip, which is provided with at least a receiving hole for containing sample liquid and a waste liquid hole for containing waste liquid.
[0036] It should be noted that, Figure 1 The arrangement of the various functional modules is only illustrative. In other embodiments, the arrangement or layout of the various functional modules is not limited and can be reasonably arranged or laid out according to actual scheduling and other requirements.
[0037] Based on the above, a typical fractionation diagnostic test includes the following steps: The sample to be tested in sample module 30 is transferred to an extraction container, and lysis buffer is added to release nucleic acid substances. Then, magnetic bead reagent is added to the extraction container, allowing nucleic acid molecules to bind to the magnetic beads at a suitable temperature. The extraction container is then transferred to extraction module 20, placing it within the magnetic field range of the magnet in extraction module 20. The magnet attracts the binding material of the magnetic beads and nucleic acid to the inner wall of the extraction container. The liquid in the extraction container is then removed using an extraction device. Next, washing solution is injected, and the extraction container is moved outside the magnetic field range of the magnet, allowing the binding material of the magnetic beads and nucleic acid to redisperse in the washing solution. Then, methods such as blowing and magnetic mixing are used to ensure sufficient contact between the binding material and the washing solution to remove impurities from the surface of the binding material. The steps of injecting washing solution, mixing, and removing washing solution can be repeated as needed. Finally, the extraction container is placed in the drying module of extraction module 20 to dry any remaining washing solution in the extraction container. Then, eluent is injected into the dried extraction container, allowing the magnetic beads and nucleic acids to separate at a suitable temperature. The extraction container, after being injected with eluent, is then transferred to the magnetic field generated by a magnet. The magnet attracts the magnetic beads, now separated from the nucleic acids, to the inner wall of the extraction container. The liquid in the extraction container is then transferred to the main body of the amplification container using an extraction device. At this point, the main body of the amplification container contains purified nucleic acid molecules. Reagents are then injected into the main body of the container, and the container is sealed with a cap. The sealed amplification container is then transferred to the amplification and detection module 10 for amplification and detection.
[0038] Reference Figures 2 to 4The sample analyzer 1 in this embodiment of the invention also includes a housing module 100 and a scheduling mechanism 200. The housing module 100 includes a housing and a first door 120. The internal space of the housing includes a first region 101, a second region 102 and a first opening. The first region 101 is used to collect waste, and the second region 102 is used to accommodate the aforementioned functional modules such as the amplification detection module 10, the extraction module 20, the sample module 30, the reagent supply device 40, the first consumable supply device 50, and the second consumable supply device. The first region 101 and the second region 102 are connected through the first opening. The dispatching mechanism 200 is used to transfer waste to the first area 101. Generally, the waste from the sample analyzer 1 includes first waste and second waste. The first waste includes the amplification container (including the aforementioned container body and the container cap connected to the container body) after the detection operation is completed, and the second waste includes the extraction container after the extraction operation is completed. In other scenarios, such as when the instrument malfunctions and needs to be emptied, the first waste may also include: the amplification container (including the aforementioned container body and the container cap connected to the container body) before or during the detection operation, the separate container body before the capping operation, or the separate container cap before the capping operation, and the second waste is the extraction container before or during the extraction operation.
[0039] Specifically, the housing includes a compartment 110 (only a portion of the structure of the compartment 110 is shown in the figure), and the housing module 100 also includes a first door 120 connected to the compartment 110. The compartment 110 acts as a partition to separate the aforementioned first area 101, and the compartment 110 is provided with the aforementioned first opening 111 (shown in the figure). Figure 6 In the storage compartment 110, the first area 101 is used to store the first waste and the second waste (for ease of description, unless otherwise specified in the following instructions, the term "waste" will be used to refer to the first waste and the second waste). The first opening 111 is used to allow waste to enter the first area 101. For example, the first opening 111 is located at the top of the compartment 110. The first door 120 can move relative to the compartment 110 to switch between an open position and a closed position. When the first door 120 is in the open position, the first opening 111 is opened, thereby allowing waste to enter the compartment through the first opening 111. When the first door 120 is in the closed position, the first opening 111 is closed, thereby isolating the waste and avoiding cross-contamination.
[0040] The scheduling mechanism 200 specifically includes a drive unit 210 and a scheduling robot 220 connected to the drive unit 210. The drive unit 210 is configured to drive the scheduling robot 220 to transfer waste into the first area 101. For example, the drive unit 210 drives the scheduling robot 220 to transfer first waste from the amplification detection module 10 to the first area 101, or to transfer second waste from the extraction 20 to the first area 101. For example, the drive unit 210 can drive the scheduling robot 220 to move in a two-dimensional or three-dimensional direction, and can also drive the scheduling robot 220 to open and close, thereby gripping or releasing waste.
[0041] This embodiment effectively improves the problem of waste in the first area 101 contaminating other areas by setting up a first area 101 for placing waste and sealing the first opening 111 of the first area 101 with a first door 120, which helps to ensure the accuracy of the test results.
[0042] Based on the foregoing embodiments, in some embodiments of the present invention, the drive unit 210 is further configured to: drive the first compartment door 120 from a closed position to an open position during the process of driving the scheduling robot 220 to transfer waste to the first area 101. That is, in addition to driving the scheduling robot 220 to move to transfer waste, the drive unit 210 can also be reused for opening the first compartment door 120. In this way, the drive mechanism for opening the first compartment door 120 can be eliminated, thereby helping to reduce equipment costs and reduce equipment size. In one embodiment, the drive unit 210 drives the scheduling robot 220 to move to transfer waste, which includes not only driving the scheduling robot 220 to perform two-dimensional or three-dimensional movements, but also driving the scheduling robot 220 itself to grasp and release waste, such as driving the scheduling robot 220 to open and close.
[0043] Based on the foregoing embodiments, in some embodiments of the present invention, reference is made to... Figures 2 to 4The scheduling mechanism 200 also includes a pushing component 230, which is configured to be driven by the driving unit 210. The pushing component 230 can be a scheduling robot 220 or a mechanism independent of the scheduling robot 220, as will be explained in subsequent embodiments. Therefore, the aforementioned "driving unit 210 driving the first compartment door 120 from the closed position to the open position" specifically means that the driving unit 210 drives the pushing component 230 to abut against the first compartment door 120, and after the pushing component 230 abuts against the first compartment door 120, it continues to drive the pushing component 230 to push the first compartment door 120 from the closed position to the open position. That is, in this embodiment, the driving unit 210 pushes the first compartment door 120 through the pushing component 230 in a physical contact manner, enabling the first compartment door 120 to move stably and ensuring that the first compartment door 120 accurately reaches the open position.
[0044] When the scheduling mechanism 200 also includes a driving component 230, in some embodiments of the present invention, reference is made to... Figures 2 to 4 The driving unit 210 includes a vertical driving component 213, a first horizontal driving component 211, and a second horizontal driving component 212. The vertical driving component 213 drives the scheduling robot 220 to move vertically, the first horizontal driving component 211 drives the scheduling robot 220 to move horizontally, and the second horizontal driving component 212 drives the scheduling robot 220 to move horizontally. The first and second horizontal directions intersect. The scheduling robot 220 is configured to transfer waste from the amplification detection module 10 to the first region 101 by moving along the vertical, first, and second horizontal directions. That is, in this embodiment, the scheduling robot 220 can move in three dimensions under the drive of the driving unit 210. For example, the first horizontal direction, the second horizontal direction, and the vertical direction are the X-axis direction, the Y-axis direction, and the Z-axis direction in the figure, respectively. More specifically, the side of the sample analyzer 1 with the user interface or facing the user during operation is defined as the front side. Based on this, the X-axis direction can be the front-back direction, and the Y-axis direction can be the left-right direction, or the X-axis direction can be the left-right direction and the Y-axis direction can be the front-back direction. For ease of understanding in conjunction with the accompanying drawings, the following description will use the X-axis direction, Y-axis direction, and Z-axis direction. In some embodiments, the drive unit 210 further includes an opening and closing drive component 214 for driving and scheduling the opening and closing of the robotic arm 220.
[0045] Specifically, each drive component includes a power section and an output section. The power section provides power, and the output section is used to connect with other drive components or the scheduling robot 220. The drive components can adopt known solutions. For example, a drive component includes a motor, a synchronous belt, synchronous pulleys, and a drive seat. The synchronous belt is wound around the synchronous pulleys at both ends. The motor drives one of the synchronous pulleys to rotate. The drive seat is connected to the synchronous belt and can be driven by the synchronous belt as the synchronous pulley rotates. Other drive components or the scheduling robot 220 are connected to the drive seat. In this case, the power section is the motor, and the output section is the drive seat. Another example is a drive component including a motor, a lead screw, and a lead screw seat. The lead screw seat is threaded to the lead screw. The motor drives the lead screw to rotate, thereby driving the lead screw seat to move along the lead screw. Other drive components or the scheduling robot 220 are connected to the lead screw seat. In this case, the power section is the motor, and the output section is the lead screw seat. Figures 2 to 4 In the embodiment shown, the first horizontal drive assembly 211 and the second horizontal drive assembly 212 are both the aforementioned motor-synchronous belt-synchronous pulley drive assemblies, and the vertical drive assembly 213 and the opening and closing drive assembly 214 are the aforementioned motor-lead screw-lead screw seat drive assemblies.
[0046] On the other hand, this embodiment does not limit the connection relationship between the driving components. For example, such as Figures 2 to 4 As shown, the scheduling robot 220 is connected to the output of the opening / closing drive assembly 214, which is connected to the output of the vertical drive assembly 213. The vertical drive assembly 213 is connected to the output of the second horizontal drive assembly 212, which is connected to the output of the first horizontal drive assembly 211. Thus, the first horizontal drive assembly 211 can drive the second horizontal drive assembly 212, the vertical drive assembly 213, and the opening / closing drive assembly 214 to move synchronously with the scheduling robot 220 along the X-axis. The second horizontal drive assembly 212 can drive the vertical drive assembly 213. The opening and closing drive assembly 214 moves synchronously with the scheduling robot 220 along the Y-axis, and the vertical drive assembly 213 can drive the opening and closing drive assembly 214 and the scheduling robot 220 to move synchronously along the Z-axis, thereby realizing the three-axis movement of the scheduling robot 220; or, for example, the scheduling robot 220 can be connected to the output part of the opening and closing drive assembly 214, the opening and closing drive assembly 214 can be connected to the output part of the second horizontal drive assembly 212, the second horizontal drive assembly 212 can be connected to the output part of the first horizontal drive assembly 211, and the first horizontal drive assembly 211 can be connected to the output part of the vertical drive assembly 213.
[0047] Based on this, in some embodiments, the aforementioned "drive unit 210 drives push component 230 to abut against the first compartment door 120, and continues to drive push component 230 to push the first compartment door 120 from the closed position to the open position after push component 230 abuts against the first compartment door 120" specifically means: the first horizontal drive component 211 drives push component 230 to move along the first horizontal direction to push the first compartment door 120 from the closed position to the open position. For example, in... Figures 2 to 4 Based on the connection relationship shown, the push component 230 is connected to the output part of the first horizontal drive component 211. The push component 230 pushes the first compartment door 120 to open by moving along the X-axis. At this time, the push component 230 and the scheduling robot 220 can move synchronously along the X-axis. The scheduling robot 220 can move independently in the Y-axis and Z-axis directions relative to the push component 230.
[0048] In other embodiments, the aforementioned "drive unit 210 drives push component 230 to abut against the first compartment door 120, and continues to drive push component 230 to push the first compartment door 120 from the closed position to the open position after push component 230 abuts against the first compartment door 120" specifically means: the second horizontal drive component 212 drives push component 230 to move along the second horizontal direction to push the first compartment door 120 from the closed position to the open position. For example, in... Figures 2 to 4 Based on the connection relationship shown, the push component 230 is connected to the output part of the second horizontal drive component 212. The push component 230 pushes the first compartment door 120 to open by moving along the Y-axis. At this time, the push component 230 and the scheduling robot 220 can move synchronously along the X-axis and Y-axis. The scheduling robot 220 can move independently in the Z-axis direction relative to the push component 230. It can be understood that at this time, the push component 230 can also push the first compartment door 120 to open by moving along the X-axis.
[0049] In other embodiments, the aforementioned "drive unit 210 drives push component 230 to abut against the first compartment door 120, and continues to drive push component 230 to push the first compartment door 120 from the closed position to the open position after push component 230 abuts against the first compartment door 120" specifically means: the vertical drive component 213 drives push component 230 to move vertically to push the first compartment door 120 from the closed position to the open position. For example, in... Figures 2 to 4Based on the connection relationship shown, the push component 230 is connected to the output part of the vertical drive component 213 or to the scheduling robot 220. The push component 230 pushes the first compartment door 120 open by moving along the Z-axis. At this time, the push component 230 and the scheduling robot 220 can move synchronously along the X-axis, Y-axis and Z-axis. It can be understood that the push component 230 can also push the first compartment door 120 open by moving along the X-axis or Y-axis. It should be noted that when the first compartment door 120 needs to be opened by translating horizontally, a steering mechanism can be set to convert the Z-axis movement of the push component 230 into a horizontal push of the first compartment door 120. For example, the steering mechanism includes two wedge-shaped seats, and the inclined surfaces of the two wedge-shaped seats abut against each other.
[0050] It should also be noted that, depending on the connection relationship of the drive components, the push component 230 can push the first compartment door 120 to open by moving along the Y-axis, and the scheduling robot 220 can move independently in the X-axis and Z-axis directions relative to the push component 230. Alternatively, the push component 230 can push the first compartment door 120 to open by moving along the Z-axis, and the scheduling robot 220 can move independently in the X-axis and Y-axis directions relative to the push component 230. Other combinations are possible and will not be detailed here.
[0051] The foregoing described an embodiment in which the scheduling robot 220 moves in a three-dimensional direction. In other embodiments, when the amplification detection module 10 and the chamber 110 are distributed in a straight line, the scheduling robot 220 can also move in a two-dimensional direction. Specifically, the drive unit 210 includes a vertical drive component 213 and a first horizontal drive component 211. The vertical drive component 213 is used to drive the scheduling robot 220 to move in a vertical direction, and the first horizontal drive component 211 is used to drive the scheduling robot 220 to move in a first horizontal direction. The scheduling robot 220 is configured to transfer a first waste or a second waste to a first area 101 by moving in the vertical and first horizontal directions.
[0052] It should be noted that the specific composition of the first horizontal drive component 211 and the vertical drive component 213 in this embodiment can be understood with reference to the aforementioned embodiments. Regarding their connection relationship, the scheduling robot 220 can be connected to the output portion of the opening and closing drive component 214, the opening and closing drive component 214 can be connected to the output portion of the first horizontal drive component 211, and the first horizontal drive component 211 can be connected to the output portion of the vertical drive component 213; or, the scheduling robot 220 can be connected to the output portion of the opening and closing drive component 214, the opening and closing drive component 214 can be connected to the output portion of the vertical drive component 213, and the vertical drive component 213 can be connected to the output portion of the first horizontal drive component 211.
[0053] Based on this, in some embodiments, the aforementioned "drive unit 210 drives push component 230 to abut against the first compartment door 120, and continues to drive push component 230 to push the first compartment door 120 from the closed position to the open position after push component 230 abuts against the first compartment door 120" specifically means: the first horizontal drive component 211 drives push component 230 to move along the first horizontal direction to push the first compartment door 120 from the closed position to the open position. For example, when the opening and closing drive component 214 is connected to the output part of the vertical drive component 213, and the vertical drive component 213 is connected to the output part of the first horizontal drive component 211, push component 230 can be connected to the output part of the first horizontal drive component 211. Push component 230 pushes the first compartment door 120 open by moving along the X-axis direction. At this time, push component 230 and scheduling robot 220 can move synchronously along the X-axis direction, and scheduling robot 220 can move independently in the Z-axis direction relative to push component 230.
[0054] In other embodiments, the aforementioned "drive unit 210 drives push component 230 to abut against the first compartment door 120, and continues to drive push component 230 to push the first compartment door 120 from the closed position to the open position after push component 230 abuts against the first compartment door 120" specifically means that: the vertical drive component 213 drives push component 230 to move in the vertical direction to push the first compartment door 120 from the closed position to the open position. For example, when the opening and closing drive component 214 is connected to the output part of the vertical drive component 213, and the vertical drive component 213 is connected to the output part of the first horizontal drive component 211, push component 230 can be connected to the output part of the vertical drive component 213. Push component 230 pushes the first compartment door 120 open by moving along the Z-axis direction. At this time, push component 230 and scheduling robot 220 can move synchronously along the X-axis direction and the Z-axis direction. It can be understood that at this time, push component 230 can also push the first compartment door 120 open by moving along the X-axis direction.
[0055] When the scheduling mechanism 200 also includes a pushing component 230, in some embodiments of the present invention, the pushing component 230 and the scheduling robot 220 are the same component. For example, the scheduling robot 220 includes a mounting base and a gripper connected to the mounting base. The mounting base is connected to the opening and closing drive component 214 and can move synchronously with the opening and closing drive component 214. The output part of the opening and closing drive component 214 is connected to the gripper and can drive the gripper to open and close relative to the mounting base. When it is necessary to push the first compartment door 120 to open, the first compartment door 120 can be pushed to open through the mounting base of the scheduling robot 220, so as not to affect the opening and closing of the gripper.
[0056] In other embodiments, the actuation component 230 is a separate component from the scheduling robot 220, and the actuation component 230 is connected to the scheduling robot 220 to maintain synchronized movement with the scheduling robot 220 at all times. Figures 2 to 4 This scenario illustrates that when the pushing component 230 pushes the first compartment door 120 to the open position, the waste held by the dispatching robot 220 is also positioned above the first opening 111, facilitating the waste to fall into the first area 101.
[0057] In other embodiments, the pushing component 230 is a different component independent of the scheduling robot arm 220, and the pushing component 230 is connected to the drive unit 210. Specifically, the pushing component 230 may be connected to the output portion of the first horizontal drive component 211, the second horizontal drive component 212, or the vertical drive component 213. For example, in... Figures 2 to 4 Based on the connection relationship shown, if the push component 230 is connected to the output part of the first horizontal drive component 211, when the push component 230 pushes the first compartment door 120 to the open position, the scheduling robot 220 can also move in the Y-axis direction to make the gripped waste above the first opening 111. It can be understood that at this time, the scheduling robot 220 can also move in the Y-axis direction first, and then the scheduling robot 220 and the push component 230 move synchronously in the X-axis direction, so that when the push component 230 pushes the first compartment door 120 to the open position, the waste gripped by the scheduling robot 220 is also just above the first opening 111.
[0058] When the scheduling mechanism 200 also includes a pushing component 230, in some embodiments of the present invention, the aforementioned "driving unit 210 is configured to drive the scheduling robot 220 to transfer the first waste or the second waste to the first area 101" specifically means: the driving unit 210 drives the scheduling robot 220 to move to the first position, and simultaneously drives the pushing component 230 to push the first door 120 from the closed position to the open position. That is, when the scheduling robot 220 moves to the first position, the pushing component 230 just pushes the first door 120 to the open position; after the first door 120 is in the open position, the driving unit 210 then drives the scheduling robot 220 to move from the first position to the second position and releases the waste so that the waste falls into the first area 101. During the process of the scheduling robot 220 moving from the first position to the second position, the pushing component 230 remains in contact with the first door 120 so that the first door 120 remains in the open position.
[0059] The second position is closer to the first opening 111 than the first position, so that the waste can fall accurately into the first opening 111. For example, both the first position and the second position are located above the first opening 111, and the second position is lower than the first position.
[0060] In some specific embodiments, the pushing component 230 is a different component independent of the scheduling robot 220, and the pushing component 230 is connected to the scheduling robot 220 to maintain synchronous movement with the scheduling robot 220 at all times. Alternatively, the pushing component 230 and the scheduling robot 220 are the same component. Based on this, during the process of the scheduling robot 220 moving from the first position to the second position, the pushing component 230 moves synchronously relative to the first door 120, and the direction of movement of the pushing component 230 relative to the first door 120 intersects with the direction of pushing the first door 120. Specifically, the direction of movement of the pushing component 230 relative to the first door 120 is perpendicular to the direction of pushing the first door 120, so that the pushing component 230 can keep the first door 120 in the open position during the process of moving relative to the first door 120. For example, the pushing component 230 and the scheduling robot 220 first move synchronously along the X-axis or Y-axis. When the scheduling robot 220 is in the first position, the pushing component 230 pushes the first door 120 to the open position. Then, the pushing component 230 and the scheduling robot 220 move synchronously downward along the Z-axis, so that the scheduling robot 220 is in the second position. During this process, although the pushing component 230 is moving relative to the first door 120, it does not move along the X-axis or Y-axis, so the first door 120 can still remain in the open position.
[0061] To reduce friction when the pushing component 230 moves relative to the first compartment door 120, one of the pushing component 230 and the first compartment door 120 is provided with a first roller 121, and the other is provided with an abutment surface 231. The pushing component 230 and the first compartment door 120 are kept in contact with each other through the first roller 121 and the abutment surface 231, and the first roller 121 is configured to roll relative to the abutment surface 231 during the movement of the pushing component 230 relative to the first compartment door 120.
[0062] For example, the push component 230 is provided with an abutment surface 231 and the first compartment door 120 is provided with a first roller 121, see reference. Figure 3 The pushing component 230 includes a pushing seat 232, one side of which (e.g., the side in the X-axis direction) is configured as an abutment surface 231. (See reference...) Figures 5 to 7The first door 120 includes a door body 123 and a first connecting seat 124. The first connecting seat 124 is connected to the door body 123, and the top of the first connecting seat 124 is higher than the door body 123. The first roller 121 is rotatably connected to the top of the first connecting seat 124.
[0063] It should be noted that, in some other embodiments, when the scheduling robot 220 moves from the first position to the second position, the pushing component 230 may also remain stationary. Figures 2 to 4 Taking the connection relationship shown as an example, the push component 230 is connected to the output part of the second horizontal drive component 212. The push component 230 and the scheduling robot 220 move synchronously along the Y-axis. When the scheduling robot 220 moves to the first position above the first opening 111, the push component 230 pushes the first compartment door 120 to the open position. Then the push component 230 remains stationary, and the vertical drive component 213 continues to drive the scheduling robot 220 to move downward to the second position. The opening and closing drive component 214 then drives the scheduling robot 220 to release the waste. Alternatively, the push component 230 is connected to the output of the first horizontal drive component 211. The push component 230 and the scheduling robot 220 move synchronously along the X-axis. When the scheduling robot 220 moves to a first position above the first opening 111, the push component 230 pushes the first door 120 to the open position. Then, the push component 230 remains stationary, and the second horizontal drive component 212 continues to drive the scheduling robot 220 to move along the Y-axis to a second position above the first opening 111. The opening and closing drive component 214 then drives the scheduling robot 220 to release waste. Alternatively, the second horizontal drive component 212 continues to drive the scheduling robot 220 to move along the Y-axis to a third position above the first opening 111. Then, the vertical drive component 213 continues to drive the scheduling robot 220 downward to a second position below the third position. The opening and closing drive component 214 then drives the scheduling robot 220 to release waste.
[0064] When the scheduling mechanism 200 also includes a pushing component 230, in some embodiments of the present invention, the aforementioned "driving unit 210 is configured to drive the scheduling robot 220 to transfer the first waste or the second waste to the first area 101" specifically means: the driving unit 210 drives the scheduling robot 220 to move to the first position, and simultaneously drives the pushing component 230 to push the first door 120 from the closed position to the open position. That is, when the scheduling robot 220 moves to the first position, the pushing component 230 just pushes the first door 120 to the open position; when the first door 120 is in the open position, the driving unit 210 drives the scheduling robot 220 to release the waste in the first position so that the waste falls into the first area 101.
[0065] The difference between this embodiment and the previous embodiment is that, in the previous embodiment, after the scheduling robot 220 moved to the first position, it needed to continue moving to a second position closer to the first opening 111 to release waste. In this embodiment, the scheduling robot 220 directly releases waste at the first position. For example, the pushing component 230 and the scheduling robot 220 first move synchronously along the X-axis or Y-axis. When the scheduling robot 220 moves to the first position above the first opening 111, the pushing component 230 pushes the first compartment door 120 to the open position. Then, the opening and closing drive component 214 drives the scheduling robot 220 to release waste.
[0066] When the scheduling mechanism 200 also includes a driving component 230, in some embodiments of the present invention, reference is made to... Figure 5 The housing module 100 also includes a first elastic element 130, which is disposed between the compartment body 110 and the first compartment door 120. The first elastic element 130 is configured to drive the first compartment door 120 from the open position to the closed position after the push component 230 separates from the first compartment door 120. In this embodiment, by setting the first elastic element 130, the automatic reset of the first compartment door 120 can be achieved. For example, the first elastic element 130 is a tension spring, with its two ends connected to the compartment body 110 and the first compartment door 120 respectively (e.g., the first connecting seat 124 of the first compartment door 120). When the first compartment door 120 moves from the closed position to the open position, the tension spring is stretched. When the push component 230 separates from the first compartment door 120, the tension spring recovers its deformation to drive the first compartment door 120 to reset.
[0067] The first elastic element 130 enables the first compartment door 120 to automatically reset, which can release waste into the first area 101, quickly close the first compartment door 120, improve efficiency, and better avoid cross-contamination.
[0068] In other embodiments, the drive unit 210 can drive the push component 230 to push the first compartment door 120 from the open position to the closed position. Taking the push component 230 pushing the first compartment door 120 along the X-axis as an example, when it is necessary to close the first compartment door 120, the drive unit 210 first drives the push component 230 to move along the three-dimensional or two-dimensional direction to the other side of the first compartment door 120 along the X-axis direction, and then drives the push component 230 to push the first compartment door 120 in the opposite direction to pushing the first compartment door 120 open, so that it moves from the open position to the closed position.
[0069] Based on the foregoing embodiments, in some embodiments of the present invention, the first compartment door 120 is slidably connected to the compartment body 110. For example, a slide rail is installed on the compartment body 110, and the first compartment door 120 (e.g., the first connecting seat 124) is connected to the slide rail via a slider. Based on this, the aforementioned "drive unit 210 drives the first compartment door 120 from the closed position to the open position" specifically refers to: driving the first compartment door 120 to move horizontally from the closed position to the open position.
[0070] When the first door 120 is slidably connected to the compartment body 110, in some embodiments of the present invention, the first door 120 seals the first opening 111 by a first sealing member 140, thereby enhancing the isolation effect on waste. For example, the first sealing member 140 is configured as a sealing sheet or a sealing ring.
[0071] To ensure the sealing effect of the first seal 140 on the first opening 111, refer to Figure 6 , Figure 7 The compartment 110 includes a main body 112, which has a first region 101. The compartment 110 also includes a first sealing portion 113 protruding from the end face of the main body 112. The first sealing portion 113 has a first sealing surface 114 with a first opening 111. Exemplarily, the first sealing portion 113 is a cylindrical structure with a through channel inside, the channel forming the first opening 111 on the first sealing surface 114 at the top of the first sealing portion 113. A first compartment door 120 has a second sealing surface 122. Exemplarily, the lower surface of the door body 123 is configured as the second sealing surface 122. A first sealing member 140 is connected to at least one of the first sealing surface 114 and the second sealing surface 122. Exemplarily, the first sealing member 140 is connected to the second sealing surface 122.
[0072] The direction of movement along the first compartment door 120 from the open position to the closed position, for example... Figure 7 From right to left, the distance between the first sealing surface 114 and the end face of the main body 112 and the distance between the second sealing surface 122 and the end face of the main body 112 both increase. For example, the first sealing surface 114 and the second sealing surface 122 are both set as inclined surfaces with the same inclination direction. In this way, when the first door 120 moves from the open position to the closed position, the first sealing surface 114 and the second sealing surface 122 can jointly squeeze the first sealing member 140, so that the first sealing member 140 can fit tightly against the first sealing surface 114.
[0073] Based on the foregoing embodiments, in some embodiments of the present invention, the first compartment door 120 is rotatably connected to the compartment body 110, and the rotation axes of both are parallel to the horizontal direction. For example, the first compartment door 120 (e.g., the first connecting seat 124) is connected to the compartment body 110 via a rotating shaft parallel to the horizontal direction. Based on this, the aforementioned "drive unit 210 drives the first compartment door 120 from the closed position to the open position" specifically refers to driving the first compartment door 120 to rotate from the closed position to the open position. Wherein, when the scheduling mechanism 200 is also provided with a pushing component 230, the first compartment door 120 can be directly rotated by the movement of the pushing component 230 along the Z-axis direction. Alternatively, a steering mechanism, such as a wedge-shaped seat, can be provided to convert the movement of the pushing component 230 along the X-axis or Y-axis direction into a push on the first compartment door 120 along the Z-axis direction.
[0074] In other embodiments, the first compartment door 120 is rotatably connected to the compartment body 110, and the rotation axes of both are parallel to the vertical direction. For example, the first compartment door 120 (e.g., the first connecting seat 124) is connected to the compartment body 110 via a rotating shaft parallel to the vertical direction. Based on this, the aforementioned "drive unit 210 drives the first compartment door 120 from the closed position to the open position" specifically means: driving the first compartment door 120 to rotate from the closed position to the open position. When the scheduling mechanism 200 is also provided with a pushing component 230, the first compartment door 120 can be directly rotated by the movement of the pushing component 230 along the X-axis or Y-axis direction. Alternatively, a steering mechanism, such as a wedge-shaped seat, can be provided to convert the movement of the pushing component 230 along the Z-axis direction into a push on the first compartment door 120 along the X-axis or Y-axis direction.
[0075] It should be noted that when the first compartment door 120 is rotatably connected to the compartment body 110, an elastic element such as a torsion spring can be used to reset the first compartment door 120.
[0076] The present invention also proposes another embodiment in which the scheduling robot arm 220 is reused for opening the first compartment door 120, as described in the following figure. Figures 8 to 10 In this embodiment, the first compartment door 120 is configured to move relative to the housing in both vertical and horizontal directions. Specifically, the first compartment door 120 can move relative to the housing in both vertical and horizontal directions simultaneously. When the housing includes the aforementioned compartment body 110, the first compartment door 120 moves relative to the compartment body 110 in both vertical and horizontal directions.
[0077] The housing includes a first sealing surface 114, and the first door 120 has a second sealing surface 122. The housing module also includes a first sealing element 140, which is connected to at least one of the first sealing surface 114 and the second sealing surface 122, and abuts against the other when the first door 120 is in the closed position to seal the first opening 111. The first sealing surface 114, the second sealing surface 122, and the first sealing element 140 in this embodiment can be understood with reference to the foregoing embodiments.
[0078] In this embodiment, the aforementioned "after the pushing component 230 abuts against the first compartment door 120, the driving unit 210 continues to drive the pushing component 230 to push the first compartment door 120 from the closed position to the open position" specifically means: after the driving unit 210 drives the pushing component 230 to push the first compartment door 120 from the closed position to the first set position or the first set distance along the first direction, the first compartment door 120 is then pushed to the open position along the second direction, and the first direction has a first included angle α with the first sealing surface 114 (shown in...). Figure 10 In the first direction, the first included angle is greater than 0 and less than or equal to 90°, meaning the first direction can be inclined or perpendicular to the first sealing surface 114, but cannot be parallel to the first sealing surface 114. Thus, the first door 120 can move along the first direction with a first included angle α to the first sealing surface 114, causing the first seal 140 to disengage from either the first sealing surface 114 or the second sealing surface 122. Compared to moving along a direction parallel to the first sealing surface 114 to disengage the first seal 140, the frictional force during disengagement is less, resulting in a smoother disengagement process. Furthermore, after the first door 120 is pushed along the first direction to disengage the first seal 140 from the sealing surface, the first opening 111 is still completely or mostly covered. Therefore, the first door 120 can move along the first direction with a second included angle β to the first sealing surface 114 (shown in...). Figure 10 The second direction continues to move to further open the first opening 111, wherein the first included angle α is greater than the second included angle β, and the second included angle β is greater than or equal to 0 and less than or equal to 90°. That is, the second direction can be inclined or perpendicular to the first sealing surface 114, or it can be parallel to the first sealing surface 114.
[0079] When the first door 120 moves first along a first direction and then along a second direction, in some embodiments of the present invention, reference is made to... Figure 8 , Figure 10The housing module also includes a guide component 150, which is fixedly disposed, exemplarily, the guide component 150 being fixedly connected to the housing 110. The guide component 150 has a first trajectory surface 151 and a second trajectory surface 152, the second trajectory surface 152 and the first trajectory surface 151 being disposed along a second direction, specifically, with... Figure 10 For example, if the second direction is the horizontal direction from right to left in the diagram, then the second trajectory surface 152 is set to the left of the first trajectory surface 151. The first trajectory surface 151 is parallel to the first direction, and the second trajectory surface 152 is parallel to the second direction, similarly... Figure 10 For example, the first trajectory surface 151 and the first direction are both inclined relative to the horizontal direction, and the second trajectory surface and the second direction are both parallel to the horizontal direction.
[0080] Based on the above structure, during the process of the drive unit 210 driving the push assembly 230 to push the first compartment door 120 from the closed position to the first set position or push it a first set distance along the first direction, the first compartment door 120 abuts against the first track surface 151 and moves relative to the first track surface 151 (e.g., Figure 10 (As shown in steps A and B); during the process of the drive unit 210 driving the push assembly 230 to push the first compartment door 120 to the open position along the second direction, the first compartment door 120 abuts against the second track surface 152 and moves relative to the second track surface 152 (as shown in steps A and B); Figure 10 (As shown in step C), thus, guided by the first trajectory surface 151 and the second trajectory surface 152, the first compartment door 120 can move along the desired trajectory. Combined with... Figure 10 It can be seen that when the first door 120 moves along the first direction from the position shown in step A to the position shown in step B, the first door 120 has already separated from the first seal 140 on the compartment body 110, but the first door 120 is still basically above the first opening 111, at which time the first opening 111 is still in a blocked state; when the first door 120 continues to move along the second direction from the position shown in step B to the position shown in step C, it can be seen that the first door 120 has obviously moved away from the first opening 111, at which time most of the first opening 111 is exposed.
[0081] For example, the first door 120 includes a door body 123 and a door track plate 128. The door body 123 is used to cooperate with the compartment body 110 to close the first opening 111, as can be understood according to the aforementioned embodiment. The door track plate 128 is fixedly connected to the door body 123, so that it can move synchronously with the door body 123. Based on this, the aforementioned "first door 120 abutting against the first track surface 151 and the second track surface 152" specifically refers to the door track plate 128 abutting against the first track surface 151 and the second track surface 152. In order to reduce the frictional force when the door track plate 128 moves along the first track surface 151 and the second track surface 152, such as... Figure 10 As shown, the first door 120 also includes a second roller 126 rotatably connected to the door track plate 128. The door track plate 128 abuts against the first track surface 151 and the second track surface 152 through the second roller 126 and moves relative to the first track surface 151 and the second track surface 152.
[0082] For example, when the first door 120 is in the closed position, the first door 120 remains in contact with the first track surface 151, so that when the first door 120 is pushed by the push component 230, it can move smoothly along the first track surface 151.
[0083] When the guide component 150 has a first trajectory surface 151 and a second trajectory surface 152, in some embodiments of the present invention, referring to... Figure 10 The first door 120 has a third track surface 125. For example, when the first door 120 includes a door track plate 128, the third track surface 125 is disposed on the door track plate 128.
[0084] During the process of the pushing component 230 pushing the first compartment door 120 from the closed position to the open position, the drive unit 210 is configured to drive the pushing component 230 and the scheduling robot 220 to move synchronously in the vertical direction, and the pushing component 230 abuts against and moves relative to the third trajectory surface 125, so that the first compartment door 120 moves relative to the guide component 150 from the first trajectory surface 151 to the second trajectory surface 152. For example, the third trajectory surface 125 is set as an inclined surface. When the pushing component 230 descends in the vertical direction and pushes the first compartment door 120 through the third trajectory surface 125, the force on the first compartment door 120 includes a horizontal component force. This component force can push the first compartment door 120 to move first along the first trajectory surface 151 and then along the second trajectory surface 152. In this way, without setting up an additional drive device, the movement of the first compartment door 120 can be achieved by relying on the cooperation of the pushing component 230 and the third trajectory surface 125. To reduce the frictional force when the pushing component 230 moves along the third trajectory surface 125, such as Figure 10 As shown, the pushing component 230 also includes a fourth roller 236, through which the pushing component 230 abuts against the third track surface 125 and moves relative to the third track surface 125.
[0085] In this embodiment, as the pushing component 230 moves along the third trajectory surface 125, the first compartment door 120 also moves relative to the second trajectory surface 152. When the first compartment door 120 moves to the open position, the position of the scheduling robot 220 at this time is defined as the first position. That is, when the scheduling robot 220 moves to the first position, the pushing component 230 just pushes the first compartment door 120 to the open position. Then the drive unit 210 is also configured to drive the scheduling robot 220 to release waste at the first position.
[0086] In other embodiments, when the scheduling robot 220 moves to the first position so that the pushing component 230 pushes the first compartment door 120 to the open position, the drive unit 210 does not drive the scheduling robot 220 to release waste in the first position. Instead, it drives the pushing component 230 to continue moving in the vertical direction synchronously with the scheduling robot 220 until the scheduling robot 220 is in the second position. Then, it drives the scheduling robot 220 to release waste in the second position so that the waste falls into the first area 101. During the process of the scheduling robot 220 moving from the first position to the second position, the pushing component 230 and the first compartment door 120 remain in contact so that the first compartment door 120 remains in the open position.
[0087] The second position is closer to the first opening 111 than the first position, so that the waste can fall accurately into the first opening 111. For example, both the first position and the second position are located above the first opening 111, and the second position is lower than the first position.
[0088] To ensure that the first door 120 remains in the open position during the movement of the scheduling robot 220 from the first position to the second position, refer to 10 and Figure 11 The push component 230 has a fourth trajectory surface 233. During the movement of the scheduling robot 220 from the first position to the second position, the push component 230 separates from the third trajectory surface 125. After separation, the fourth trajectory surface 233 abuts against the first door 120 and moves relative to it, keeping the first door 120 in the open position. Specifically, when the scheduling robot 220 is in the first position, the push component 230 abuts against the end of the third trajectory surface 125. When the scheduling robot 220 begins to move to the second position, the push component 230 also simultaneously begins to separate from the third trajectory surface 125, and the first door 120 begins to abut against the fourth trajectory surface 233. For example, the fourth trajectory surface 233 is perpendicular to the second trajectory surface 152, so that when the first door 120 moves along the fourth trajectory surface 233, the first door 120 will not move along the second trajectory surface 152. For example, the second trajectory surface 152 is parallel to the horizontal direction, and the fourth trajectory surface 233 is parallel to the vertical direction.
[0089] To reduce the frictional force when the first door 120 moves along the fourth trajectory surface 233, such as Figure 10 , Figure 11 As shown, the first door 120 includes a third roller 127. For example, the third roller 127 is rotatably connected to the door track plate 128. Thus, the first door 120 abuts against the fourth track surface 233 via the third roller 127 and moves relative to the fourth track surface 233.
[0090] In this embodiment, by providing a fourth trajectory surface 233 on the pushing component 230, it is helpful to reduce the overall size. Specifically, the pushing component 230 itself needs to move in the vertical direction and has a certain length in the vertical direction. Therefore, the pushing component 230 has sufficient design space in the vertical direction. Thus, when the fourth trajectory surface 233 extending in the vertical direction is provided on the pushing component 230, it will not cause a change in the size of the pushing component 230 in the vertical direction. On the other hand, since the fourth trajectory surface 233 does not need to be provided on the first compartment door 120, the space required for arranging the fourth trajectory surface 233 can be saved. The size of the first compartment door 120 in the vertical direction can be made smaller, thereby reducing the overall size accordingly.
[0091] When the guide component 150 has a first trajectory surface 151 and a second trajectory surface 152, in some embodiments of the present invention, referring to... Figure 10 The first door 120 has a third trajectory surface 125, and the pushing component 230 has a fourth trajectory surface 233. During the process of the pushing component 230 pushing the first door 120 from the closed position to the open position, the drive unit 210 is configured to drive the pushing component 230 and the scheduling robot 220 to move synchronously in the vertical direction so that the pushing component 230 performs a first stroke and a second stroke in sequence. During the first stroke, the pushing component 230 abuts against the third trajectory surface 125 and moves relative to the third trajectory surface 125 so that the first door 120 moves relative to the guide component 150 from the first trajectory surface 151 to the second trajectory surface 152. During the second stroke, the pushing component 230 separates from the third trajectory surface 125. After the pushing component 230 separates from the third trajectory surface 125, the fourth trajectory surface 233 abuts against the first door 120 and moves relative to the first door 120 so that the first door 120 remains in the current position. This part can be understood with reference to the aforementioned embodiments.
[0092] The difference between this embodiment and the previous embodiment is that in the previous embodiment, the first compartment door 120 was in the open position after the fourth roller 236 disengaged from the third track surface 125, or in other words, after the third roller 127 abutted against the fourth track surface 233. In this embodiment, the first compartment door 120 has not yet moved to the open position after the fourth roller 236 disengaged from the third track surface 125, or in other words, after the third roller 127 abutted against the fourth track surface 233. Specifically, refer to... Figure 12 , Figure 13 The actuating component 230 also has a fifth trajectory surface 234, which is connected to the upper side of the fourth trajectory surface 233. During the third stroke of the actuating component 230, the fourth trajectory surface 233 separates from the first door 120, and the fifth trajectory surface 234 abuts against and moves relative to the first door 120, thereby pushing the first door 120 to move relative to the second trajectory surface 152 in the second direction to the open position, for example from... Figure 14 The position shown in step D is further moved to the position shown in step E. The position shown in step E is the open position in this embodiment. That is, when other structures are the same, the moving distance of the first door 120 along the second trajectory surface 152 in this embodiment is greater than the moving distance of the first door 120 along the second trajectory surface 152 in the previous embodiment. Specifically, when the pushing component 230 begins to perform the third stroke, the first door 120 also begins to disengage from the fourth trajectory surface 233 and begins to abut against the fifth trajectory surface 234.
[0093] For example, the fifth trajectory surface 234 is set as an inclined plane. When the first door 120 moves along the fifth trajectory surface 234, the force exerted by the fifth trajectory surface 234 on the first door 120 includes a component force parallel to the direction of the second trajectory surface 152. This component force can push the first door 120 to continue moving along the second trajectory surface 152.
[0094] As the first door 120 moves along the fifth trajectory surface 234, the first door 120 also moves relative to the second trajectory surface 152. When the first door 120 moves to the open position, the position of the scheduling robot 220 at this time is defined as the first position. That is, when the scheduling robot 220 moves to the first position, the pushing component 230 just pushes the first door 120 to the open position. Then the drive unit 210 is also configured to drive the scheduling robot 220 to release waste at the first position.
[0095] Compared to the solution where the first compartment door 120 is directly pushed to the open position by the cooperation of the fourth roller 236 and the third track surface 125, in this embodiment, the first compartment door 120 is first pushed into a partially open state by the fourth roller 236 and the third track surface 125, and then the first compartment door 120 is further pushed to the open position by the fifth track surface 234 on the pushing component 230. Therefore, the length of the third track surface 125 on the first compartment door 120 can be reduced, that is, the volume of the first compartment door 120 can be smaller. The fifth track surface 234 on the pushing component 230 does not cause the size of the pushing component 230 to increase (see the above for the specific reasons), so the overall volume can be reduced.
[0096] In other embodiments, when the scheduling robot 220 moves to the first position so that the pushing component 230 pushes the first compartment door 120 to the open position, the drive unit 210 does not drive the scheduling robot 220 to release waste in the first position. Instead, it drives the pushing component 230 to move synchronously with the scheduling robot 220 in the vertical direction until the scheduling robot 220 is in the second position. Then, it drives the scheduling robot 220 to release waste in the second position so that the waste falls into the first area 101.
[0097] The second position is closer to the first opening 111 than the first position, so that the waste can fall accurately into the first opening 111. For example, both the first position and the second position are located above the first opening 111, and the second position is lower than the first position.
[0098] To ensure that the first door 120 remains in the open position during the movement of the scheduling robot arm 220 from the first position to the second position, refer to... Figure 13 The pushing component 230 has a sixth trajectory surface 235, which is connected to the upper side of the fifth trajectory surface 234. During the movement of the scheduling robot 220 from the first position to the second position, the first door 120 separates from the fifth trajectory surface 234. After the first door 120 separates from the fifth trajectory surface 234, the sixth trajectory surface 235 abuts against the first door 120 and moves relative to the first door 120, so that the first door 120 remains in the open position. Specifically, when the scheduling robot 220 is in the first position, the first door 120 abuts against the end of the fifth trajectory surface 234. When the scheduling robot 220 begins to move to the second position, the first door 120 also simultaneously begins to separate from the fifth trajectory surface 234, and the first door 120 begins to abut against the sixth trajectory surface 235. For example, the sixth trajectory surface 235 is perpendicular to the second trajectory surface 152, so that when the first door 120 moves along the sixth trajectory surface 235, the first door 120 will not move along the second trajectory surface 152. For example, the second trajectory surface 152 is parallel to the horizontal direction, and the sixth trajectory surface 235 is parallel to the vertical direction.
[0099] When the first door 120 moves first along a first direction and then along a second direction, in some embodiments of the present invention, the first sealing surface 114 and the second sealing surface 122 are arranged parallel to each other and both are inclined relative to the horizontal direction. The first direction is perpendicular to the first sealing surface 114, allowing the first door 120 to move along a direction perpendicular to the first sealing surface 114 so that the first seal 140 disengages from the sealing surface, minimizing friction. In other embodiments, the second direction is parallel to the horizontal direction, allowing the first door 120 to continue moving horizontally away from the first opening 111.
[0100] In other embodiments, the first direction may also be inclined relative to the first sealing surface 114.
[0101] When the first door 120 moves first along a first direction and then along a second direction, in some embodiments of the present invention, reference is made to... Figure 9 The housing module also includes a first sliding component 160, a second sliding component 170, and a second connecting seat 180. The first door 120 is connected to the second connecting seat 180 via the first sliding component 160, and the second connecting seat 180 is connected to the housing via the second sliding component 170. The first door 120 can slide horizontally relative to the second connecting seat 180, and the second connecting seat 180 can slide vertically relative to the housing. Alternatively, the first door 120 can slide vertically relative to the second connecting seat 180, and the second connecting seat 180 can slide horizontally relative to the housing.
[0102] Based on this, the housing module also includes a second elastic element 190 and a third elastic element 1100. The second elastic element 190 is connected between the first compartment door 120 and the second connecting seat 180, and the third elastic element 1100 is connected between the second connecting seat 180 and the housing. The second elastic element 190 and the third elastic element 1100 are configured to drive the first compartment door 120 to reset to the closed position after the pushing assembly 230 disengages from the first compartment door 120. For example, the second elastic member 190 is arranged in a generally vertical direction and is used to apply a generally vertical force to the first door 120. The third elastic member 1100 is arranged in a generally horizontal direction and is used to apply a generally horizontal force to the first door 120. When the drive unit 210 drives the push assembly 230 and the scheduling robot 220 to move upward synchronously, the second elastic member 190 and the third elastic member 1100 also synchronously drive the first door 120 to move along the second track surface 152 and then along the first track surface 151 to the closed position. When the door 120 is in the closed position, it remains in contact with the first track surface 151.
[0103] Based on the foregoing embodiments, in some embodiments of the present invention, the sample analyzer further includes a first storage device located within the first region 101 for storing waste. That is, the aforementioned waste being transferred to or discarded within the first region 101 specifically refers to being transferred to or discarded within the first storage device. The first storage device may be a mechanism independent of and separate from the housing. Thus, by collecting waste uniformly through the first storage device, the first storage device can be removed from the housing and the waste can be dumped to other locations, facilitating timely cleaning of the waste within the first region 101.
[0104] In this embodiment, the first storage device has an opening facing the first opening 111, so that when the scheduling robot releases waste, the waste can fall into the first storage device under the action of gravity, which facilitates the collection of waste.
[0105] In other embodiments, the opening of the first storage device may also be offset from the first opening 111. In this case, the housing further includes a guide structure disposed between the first opening 111 and the opening of the first storage device. The guide structure defines a guide channel, one end of which communicates with the first opening 111, and the other end of which faces the opening of the first storage device. For example, when the housing includes the aforementioned compartment 110, the guide structure may be part of the compartment 110 or a separate structure independent of the compartment 110.
[0106] When the sample analyzer also includes a first storage device, in some embodiments of the present invention, the housing further includes a second opening communicating with the first region 101 and the external space of the housing. The housing module also includes a second door connected to the housing, and the second door is movable relative to the housing to open or close the second opening. When the second door opens the second opening, the first storage device can be moved out of the first region 101 through the second opening. Thus, when it is necessary to clean up waste in the first region 101, it is only necessary to open the second door and remove the first storage device. To facilitate the removal of the first storage device, the second opening is located on a side suitable for operation, for example, the second opening is located on the front side of the housing facing the user.
[0107] In this embodiment, the housing module further includes a second seal, which is connected to at least one of the housing and the second compartment door, and fits against the other when the second compartment door closes the second opening to seal the second opening and prevent sample leakage and contamination.
[0108] In some specific embodiments, a slide rail is also provided in the first region 101 to facilitate the removal of the first storage device, and the first storage device can slide in the first region 101 via the slide rail.
[0109] The foregoing mentioned embodiments of collecting solid waste using the first area 101. In some embodiments of the present invention, liquid waste such as waste liquid can also be collected. Specifically, the sample analyzer includes a second storage device and a sealing cap. The second storage device has a receiving cavity for storing waste liquid, and the sealing cap is sealed to the second storage device to close the receiving cavity.
[0110] The sample analyzer also includes a waste liquid needle and a waste liquid pipeline. The waste liquid needle is sealed to the sealing cap via the waste liquid pipeline. After the test is completed, the waste liquid and the amplification container need to be disposed of separately. Therefore, in this embodiment, the waste liquid is first drawn from the amplification container using the waste liquid needle and then transported to the second storage device via the waste liquid pipeline for storage. Then, the aforementioned scheduling robot is used to transfer the amplification container to the first area 101 for storage. Specifically, one end of the waste liquid pipeline is connected to the waste liquid needle, and the other end is connected to the sealing cap. The connection between the waste liquid pipeline and the sealing cap is kept sealed. For example, the sealing cap is provided with a through hole, and one end of the waste liquid pipeline is connected to or passes through the through hole. The connection between the two is kept sealed by sealing structures such as sealant and sealing rings, so that the waste liquid from the waste liquid needle can enter the second storage device without leakage through the waste liquid pipeline.
[0111] In this embodiment, the sealing cap is detachably connected to the second storage device. When it is necessary to clean the waste liquid in the sample analyzer, the sealing cap can be separated from the second storage device. The sealing cap and its attached waste liquid pipeline remain inside the sample analyzer, while the second storage device can be removed from the sample analyzer for waste liquid disposal. For example, the sealing cap can be detachably connected to the second storage device via a threaded connection, allowing it to be removed by rotation; alternatively, the sealing cap can be at least partially inserted into the second storage device, allowing it to be removed by pulling it out.
[0112] When the sample analyzer includes a second storage device, in some embodiments of the present invention, the second storage device is located within a first region 101, thereby further preventing contamination by containing waste and waste liquid in the first region 101, which is isolated from the second region 102.
[0113] Based on the foregoing embodiments, in some embodiments of the present invention, the second region 102 is further divided into multiple sub-regions, specifically, see [reference]. Figure 1 The second region 102 also includes a sample area 1021. The sample analyzer also includes the aforementioned sample module 30, which is a sample container for holding biological samples to be extracted. The sample module 30 is located within the sample area 1021. When the first door 120 is in the closed position, the first region 101 and the sample area 1021 are not connected, thereby preventing waste or waste liquid in the first region 101 from contaminating the samples in the sample area 1021.
[0114] In some embodiments, the second region 102 further includes an extraction region 1022, where the extraction module 20 is located. When the first door 120 is in the closed position, the first region 101 is not connected to the extraction region 1022, thereby preventing waste or waste liquid in the first region 101 from contaminating the nucleic acid extraction solution in the extraction region 1022.
[0115] In other embodiments, the second region 102 further includes an amplification region 1023, within which the amplification detection module 10 is located. When the first door is in the closed position, the first region 101 and the amplification region 1023 are not connected, thereby preventing waste or waste liquid in the first region 101 from contaminating the nucleic acid extraction solution in the amplification region 1023.
[0116] In other embodiments, the second region 102 further includes a consumables area 1024, and the sample analyzer further includes a first consumables supply device 50, a second consumables supply device, and a reagent supply device 40. The first consumables supply device 50 is used to provide at least an extraction container, the second consumables supply device is used to provide at least an amplification container, and the reagent supply device 40 is used to supply reagents. At least one of the first consumables supply device 50, the second consumables supply device, and the reagent supply device 40 is located within the consumables area 1024. When the first compartment door is in the closed position, the first region 101 is not in communication with the consumables area, thereby preventing waste or waste liquid in the first region 101 from contaminating the consumables in the consumables area 1024.
[0117] Based on the foregoing embodiments, in some embodiments of the present invention, reference is made to... Figure 1 The first region 101 includes an independently set first sub-region 1011 and a second sub-region 1012. Both the first sub-region 1011 and the second sub-region 1012 have the aforementioned first opening 111. The first sub-region 1011 is adjacent to the amplification and detection module 10 compared to the extraction module 20, and the second sub-region 1012 is adjacent to the extraction module 20 compared to the amplification and detection module 10. Based on this, the driving unit is configured to drive the scheduling robot 220 to transfer the first waste from the amplification and detection module 10 to the first sub-region 1011, or the second waste from the extraction module 20 to the second sub-region 1012. In this way, the transfer path of the first waste and the second waste can be shortened, which helps to improve the transfer efficiency.
[0118] The embodiments of the present invention have been described in detail above with reference to the accompanying drawings. However, the present invention is not limited to the above embodiments, and various changes can be made within the scope of knowledge possessed by those skilled in the art without departing from the spirit of the present invention. Furthermore, the embodiments of the present invention and the features thereof can be combined with each other unless otherwise specified.
Claims
1. A sample analyzer, characterized in that, Includes a casing module, extraction module, amplification and detection module, and scheduling mechanism: The extraction module is used to extract nucleic acids from liquid containing at least the sample in the extraction container to obtain a nucleic acid extract solution; The amplification and detection module is used to amplify and detect a liquid containing at least the nucleic acid extract placed in an amplification container. The amplification container includes a container body for containing the liquid containing at least the nucleic acid extract, and a container cap for sealing the container body. The housing module includes a housing and a first door. The housing has a first region, a second region, and a first opening connecting the first region and the second region. The second region is used to accommodate the extraction module and the amplification detection module. The first region is used to store a first waste from the amplification detection module or a second waste from the extraction module. The first waste includes the amplification container, the container body separated from the container cap, or the container cap separated from the container body. The second waste includes the extraction container. The first door is movable relative to the housing to switch between an open position and a closed position. When the first door is in the open position, the first opening is open. When the first door is in the closed position, the first opening is closed. The scheduling mechanism includes a drive unit and a scheduling robot connected to the drive unit. When the first compartment door is in the open position, the drive unit is configured to drive the scheduling robot to transfer the first waste or the second waste to the first area.
2. The sample analyzer according to claim 1, characterized in that, The drive unit is also configured to drive the first compartment door from the closed position to the open position during the process of driving the dispatching robot to transfer the first waste or the second waste to the first area.
3. The sample analyzer according to claim 1, characterized in that, The scheduling mechanism also includes a propulsion component; The drive unit drives the first compartment door from the closed position to the open position, including: the drive unit drives the push component to abut against the first compartment door, and after the push component abuts against the first compartment door, it continues to drive the push component to push the first compartment door from the closed position to the open position.
4. The sample analyzer according to claim 3, characterized in that, The drive unit includes a vertical drive component, a first horizontal drive component, and a second horizontal drive component. The vertical drive component drives the scheduling robot to move in a vertical direction. The first horizontal drive component drives the scheduling robot to move in a first horizontal direction. The second horizontal drive component drives the scheduling robot to move in a second horizontal direction. The first horizontal direction and the second horizontal direction intersect. The scheduling robot is configured to transfer the first waste or the second waste to the first area by moving along the vertical direction, the first horizontal direction, and the second horizontal direction. Wherein, the driving unit continues to drive the pushing component to push the first compartment door from the closed position to the open position after the pushing component abuts against the first compartment door, including: The first horizontal drive component drives the push component to move along the first horizontal direction to push the first compartment door from the closed position to the open position; Alternatively, the second horizontal drive component drives the push component to move along the second horizontal direction to push the first compartment door from the closed position to the open position; Alternatively, the vertical drive component drives the push component to move along the vertical direction to push the first compartment door from the closed position to the open position; Alternatively, the drive unit includes a vertical drive component and a first horizontal drive component, the vertical drive component being used to drive the scheduling robot to move in a vertical direction, and the first horizontal drive component being used to drive the scheduling robot to move in a first horizontal direction, the scheduling robot being configured to transfer the first waste or the second waste to the first area by moving in the vertical direction and the first horizontal direction; Wherein, the driving unit continues to drive the pushing component to push the first compartment door from the closed position to the open position after the pushing component abuts against the first compartment door, including: The first horizontal drive component drives the push component to move along the first horizontal direction to push the first compartment door from the closed position to the open position; Alternatively, the vertical drive component drives the push component to move along the vertical direction to push the first compartment door from the closed position to the open position.
5. The sample analyzer according to claim 3, characterized in that, The pushing component is the same component as the scheduling robot; or, the pushing component is a different component independent of the scheduling robot, and the pushing component is connected to the scheduling robot to move synchronously with the scheduling robot; or, the pushing component is a different component independent of the scheduling robot, and the pushing component is connected to the drive unit.
6. The sample analyzer according to claim 3, characterized in that, The drive unit drives the scheduling robot to move to transfer the first waste or the second waste to the first area, including: the drive unit drives the scheduling robot to move to a first position and simultaneously drives the push component to push the first compartment door from the closed position to the open position, and when the first compartment door is in the open position, drives the scheduling robot to move from the first position to a second position and release the first waste or the second waste, so that the first waste or the second waste falls into the first area; Wherein, the second position is closer to the first opening than the first position, and during the process of the scheduling robot moving from the first position to the second position, the pushing component remains in contact with the first compartment door so that the first compartment door remains in the open position; Preferably, the pushing component is a different component independent of the scheduling robot, and the pushing component moves synchronously with the scheduling robot; or, the pushing component and the scheduling robot are the same component. During the process of the scheduling robot moving from the first position to the second position, the pushing component moves synchronously relative to the first compartment door, and the direction of movement of the pushing component relative to the first compartment door intersects with the direction of pushing the pushing component to push the first compartment door; More preferably, one of the pushing component and the first compartment door is provided with a first roller, and the other is provided with an abutting surface. The pushing component and the first compartment door are kept in contact with the abutting surface through the first roller, and the first roller is configured to roll relative to the abutting surface during the movement of the pushing component relative to the first compartment door.
7. The sample analyzer according to claim 3, characterized in that, The drive unit drives the scheduling robot to move to transfer the first waste or the second waste to the first area, including: the drive unit drives the scheduling robot to move to a first position and simultaneously drives the push component to push the first compartment door from the closed position to the open position; and when the first compartment door is in the open position, the drive unit drives the scheduling robot to release the first waste or the second waste at the first position so that the first waste or the second waste falls into the first area.
8. The sample analyzer according to claim 3, characterized in that, The housing module further includes a first elastic element, which is disposed between the housing and the first compartment door and is configured to drive the first compartment door from the open position to the closed position after the pushing component is separated from the first compartment door.
9. The sample analyzer according to claim 3, characterized in that, The first compartment door is configured to move relative to the housing in both a vertical and horizontal direction. The housing includes a first sealing surface, and the first compartment door has a second sealing surface. The housing module also includes a first sealing element, which is connected to at least one of the first sealing surface and the second sealing surface, and abuts against the other when the first compartment door is in the closed position to seal the first opening. After the pushing component abuts against the first compartment door, the driving unit continues to drive the pushing component to push the first compartment door from the closed position to the open position, including: the driving unit drives the pushing component to push the first compartment door from the closed position to the first set position or pushes it a first set distance along the first direction, and then pushes the first compartment door to the open position along the second direction, wherein the first angle between the first direction and the first sealing surface is greater than the second angle between the second direction and the first sealing surface, the first angle is greater than 0 and less than or equal to 90°, and the second angle is greater than or equal to 0 and less than or equal to 90°.
10. The sample analyzer according to claim 9, characterized in that, The housing module also has a guiding component, which has a first trajectory surface and a second trajectory surface. The second trajectory surface and the first trajectory surface are arranged along the second direction. The first trajectory surface is parallel to the first direction, and the second trajectory surface is parallel to the second direction. Specifically, during the process where the drive unit drives the push assembly to push the first compartment door from the closed position to the first set position or push it a first set distance along the first direction, the first compartment door abuts against the first track surface and moves relative to the first track surface; during the process where the drive unit drives the push assembly to push the first compartment door to the open position along the second direction, the first compartment door abuts against the second track surface and moves relative to the second track surface. Preferably, the first compartment door has a third trajectory surface. During the process of the pushing component pushing the first compartment door from the closed position to the open position, the drive unit is configured to drive the pushing component to move synchronously with the scheduling robot in the vertical direction, and the pushing component abuts against the third trajectory surface and moves relative to the third trajectory surface, so that the first compartment door moves relative to the guide component from the first trajectory surface to the second trajectory surface. When the first compartment door is in the open position, the dispatching robot is in the first position, wherein: The drive unit is also configured to drive the scheduling robot to release the first waste or the second waste at the first position; Alternatively, the drive unit is further configured to drive the pushing component to move synchronously with the scheduling robot in a vertical direction until the scheduling robot is in a second position, and drive the scheduling robot to release the first waste or the second waste in the second position so that the first waste or the second waste falls into the first area, the second position being lower than the first position; The pushing component has a fourth trajectory surface. During the process of the scheduling robot moving from the first position to the second position, the pushing component separates from the third trajectory surface. After the pushing component separates from the third trajectory surface, the fourth trajectory surface abuts against the first compartment door and moves relative to the first compartment door so that the first compartment door remains in the open position. Preferably, the first door has a third trajectory surface, and the pushing component has a fourth and a fifth trajectory surface. The fifth trajectory surface is connected to the upper side of the fourth trajectory surface. During the process of the pushing component pushing the first door from the closed position to the open position, the drive unit is configured to drive the pushing component and the scheduling robot to move synchronously in the vertical direction so that the pushing component sequentially performs a first stroke, a second stroke, and a third stroke. During the first stroke, the pushing component abuts against the third trajectory surface and moves relative to the third trajectory surface, so that the first door moves relative to the guide component from the first trajectory surface. The push component moves to the second trajectory surface; during the second stroke of the push component, the push component separates from the third trajectory surface. After the push component separates from the third trajectory surface, the fourth trajectory surface abuts against the first compartment door and moves relative to the first compartment door to keep the first compartment door in its current position; during the third stroke of the push component, the fourth trajectory surface separates from the first compartment door. After the fourth trajectory surface separates from the first compartment door, the fifth trajectory surface abuts against the first compartment door and moves relative to the first compartment door to push the first compartment door to move relative to the second trajectory surface along the second direction to the open position; When the first compartment door is in the open position, the dispatching robot is in the first position, wherein: The drive unit is also configured to drive the scheduling robot to release the first waste or the second waste at the first position; Alternatively, the drive unit is further configured to drive the pushing component to move synchronously with the scheduling robot in a vertical direction until the scheduling robot is in a second position, and drive the scheduling robot to release the first waste or the second waste in the second position so that the first waste or the second waste falls into the first area, the second position being lower than the first position; The pushing component has a sixth trajectory surface connected to the upper side of the fifth trajectory surface. During the process of the scheduling robot moving from the first position to the second position, the fifth trajectory surface separates from the first door. After the fifth trajectory surface separates from the first door, the sixth trajectory surface abuts against the first door and moves relative to the first door so that the first door remains in the open position.
11. The sample analyzer according to claim 9, characterized in that, The first sealing surface and the second sealing surface are arranged parallel to each other and are both inclined relative to the horizontal direction, wherein the first direction is perpendicular to the first sealing surface, and / or the second direction is parallel to the horizontal direction; And / or, the housing module further includes a first sliding assembly, a second sliding assembly, and a second connecting seat, wherein the first compartment door is connected to the second connecting seat via the first sliding assembly, and the second connecting seat is connected to the housing via the second sliding assembly, wherein the first compartment door is slidable relative to the second connecting seat in the horizontal direction, and the second connecting seat is slidable relative to the housing in the vertical direction; or, the first compartment door is slidable relative to the second connecting seat in the vertical direction, and the second connecting seat is slidable relative to the housing in the horizontal direction. The housing module further includes a second elastic element and a third elastic element. The second elastic element is connected between the first compartment door and the second connecting seat, and the third elastic element is connected between the second connecting seat and the housing. The second elastic element and the third elastic element are configured to drive the first compartment door to reset to the closed position after the pushing component disengages from the first compartment door.
12. The sample analyzer according to claim 1, characterized in that, The first compartment door is slidably connected to the housing, wherein the drive unit drives the first compartment door from the closed position to the open position, including: driving the first compartment door to move horizontally from the closed position to the open position; Preferably, the housing includes a compartment, the compartment includes a main body and a first sealing portion protruding from the end face of the main body, the main body has a first region, the first sealing portion has a first sealing surface and a first opening, the first compartment door has a second sealing surface, and along the moving direction of the first compartment door from the open position to the closed position, the distance from the first sealing surface to the end face and the distance from the second sealing surface to the end face both increase; The housing module further includes a first seal, which is connected to at least one of the first sealing surface and the second sealing surface, and abuts against the other when the first door is in the closed position to seal the first opening.
13. The sample analyzer according to claim 1, characterized in that, The first compartment door is rotatably connected to the housing, and the rotation axes of the two are parallel to the horizontal or vertical direction. The driving unit drives the first compartment door from the closed position to the open position, including: driving the first compartment door to rotate from the closed position to the open position.
14. The sample analyzer according to claim 1, characterized in that, The sample analyzer further includes a first storage device located in the first area for storing the first waste and the second waste, the first storage device having an opening facing the first opening.
15. The sample analyzer according to claim 14, characterized in that, The housing also includes a second opening that connects the first region and the external space of the housing. The housing module also includes a second door that can move relative to the housing to open or close the second opening. When the second door opens the second opening, the first storage device can be moved out of the first region through the second opening. Preferably, the housing module further includes a second seal, which is connected to at least one of the housing and the second compartment door, and abuts against the other to seal the second opening when the second compartment door closes the second opening.
16. The sample analyzer according to claim 1, characterized in that, The sample analyzer includes a second storage device and a sealing cap. The second storage device has a receiving cavity for storing waste liquid, and the sealing cap is sealed to the second storage device to close the receiving cavity. The sample analyzer also includes a waste liquid needle and a waste liquid pipeline. The waste liquid needle is sealed to the sealing cap through the waste liquid pipeline. The waste liquid needle is used to draw waste liquid from the amplification container and transport the waste liquid to the second storage device through the waste liquid pipeline. Preferably, the second storage device is located within the first area; Preferably, the sealing cap is detachably connected to the second storage device.
17. The sample analyzer according to claim 1, characterized in that, The housing includes a compartment, the first region being formed inside the compartment to separate the first region from the second region, the compartment having the first opening.
18. The sample analyzer according to claim 1, characterized in that, The second area also includes a sample area, and the sample analyzer also includes a sample module. The sample module is used to hold a sample container containing biological samples to be extracted. The sample module is located in the sample area. When the first door is in the closed position, the first area and the sample area are not connected. And / or, the second region further includes an extraction area, the extraction module being located in the extraction area, and when the first compartment door is in the closed position, the first region and the extraction area are not connected; And / or, the second region further includes an amplification region, the amplification detection module is located in the amplification region, and when the first door is in the closed position, the first region is not connected to the amplification region; And / or, the second area further includes a consumables area, and the sample analyzer further includes a first consumables supply device, a second consumables supply device, and a reagent supply device. The first consumables supply device is at least used to provide an extraction container, the second consumables supply device is at least used to provide the amplification container, and the reagent supply device is used to supply reagents. At least one of the first consumables supply device, the second consumables supply device, and the reagent supply device is located within the consumables area. When the first compartment door is in the closed position, the first area is not connected to the consumables area.
19. The sample analyzer according to claim 1, characterized in that, The first region includes a first sub-region and a second sub-region that are set independently. Both the first sub-region and the second sub-region have the first opening. The driving unit is configured to drive the scheduling robot to transfer the first waste from the amplification detection module to the first sub-region, or to transfer the second waste from the extraction module to the second sub-region.