Biopsy gun capable of forming a hemostatic hydrogel in the puncture channel simultaneously with the biopsy sampling

By integrating the automatic release and cross-linking reaction of hydrogel precursor powder into the biopsy gun, the problems of low hemostasis efficiency and tumor cell spread after biopsy gun are solved, achieving rapid and effective hemostasis and simplifying operation.

CN122272081APending Publication Date: 2026-06-26THE FIRST AFFILIATED HOSPITAL OF MEDICAL COLLEGE OF XIAN JIAOTONG UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
THE FIRST AFFILIATED HOSPITAL OF MEDICAL COLLEGE OF XIAN JIAOTONG UNIV
Filing Date
2026-05-06
Publication Date
2026-06-26

AI Technical Summary

Technical Problem

Existing biopsy guns have low postoperative hemostasis efficiency, are complex to operate, and pose risks of puncture stimulation causing tumor cell spread and needle tract implantation.

Method used

A biopsy gun is designed to automatically and synchronously release absorbable bodily fluid and cross-linking hydrogel precursor powder into the puncture channel after biopsy sampling. The driving mechanism of the biopsy gun is used to achieve precise powder delivery and cross-linking, forming a self-healing hydrogel to achieve rapid and effective physical occlusion and chemical coagulation.

Benefits of technology

It achieves integrated operation of biopsy sampling and hemostasis, ensuring that hemostatic materials are accurately delivered to the deep part of the puncture wound, quickly forming a biophysical barrier, simplifying the operation and reducing the risk of tumor cell spread.

✦ Generated by Eureka AI based on patent content.

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Abstract

A biopsy gun capable of simultaneously forming a hemostatic hydrogel within the puncture channel after biopsy sampling is disclosed. The gun comprises a cannula that is ejectibly mounted to the gun body, multiple powder storage chambers arranged around a central through-hole, each with a puncture-proof bottom at the end furthest from the gun body. Two types of hydrogel precursor powders capable of cross-linking with bodily fluids are alternately placed in the powder storage chambers. A needle core is ejectibly mounted to the gun body and passes through the central through-hole, with a sampling groove at the end furthest from the gun body. Multiple needles connected to the proximal end of the needle core are inserted into the powder storage chambers in an L-shape. A medical silicone plug is fitted onto the needle, forming a sealed environment with the powder storage chambers. Upon activation, the needle core ejects first, and the needles, along with the silicone plug, puncture the bottom of the powder storage chambers, generating a pulsed pressure that releases the two precursor powders into the wound. The cannula ejects later to cut the tissue and complete the sampling. After sampling, the needle core and cannula are withdrawn, and the hydrogel precursor powders absorb blood from the wound, forming a hydrogel in situ to fill the wound.
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