A medical sponge for sterilization, anti-fouling and healing promotion and a preparation method thereof
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- SHAANXI NORMAL UNIV
- Filing Date
- 2026-05-13
- Publication Date
- 2026-07-17
AI Technical Summary
Existing medical sponges present a contradiction in achieving both antibacterial and antifouling functions, and are difficult to meet the needs of individualized treatment, especially the need to promote healing of chronic, difficult-to-heal wounds.
A "core-shell" bilayer protein nanocoating was constructed on the surface of a medical sponge. The inner layer was loaded with antimicrobial peptides and growth factors, while the outer layer was grafted with antifouling functional components to form an antifouling layer. Functional separation was achieved by utilizing protein self-assembly.
It achieves highly efficient sterilization, anti-fouling and healing-promoting functions, reduces dressing adhesion to wounds, promotes fibroblast migration and healing, is suitable for various medical sponge surfaces, has good biocompatibility, and allows for controllable drug release.
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Figure CN122399083A_ABST