A medical raman spectroscopy detection device

Abstract

The application relates to the field of light detection facilities, in particular to a medical Raman spectrum detection equipment which comprises a Raman spectrum detector, a limiting frame is fixedly arranged in the middle of a detection table of the Raman spectrum detector, a pipe base is slidably arranged in the limiting frame, a positioning piece is arranged between the pipe base and the limiting frame, accommodating cavities are formed in the two ends of the pipe base, pipe fixing pieces are arranged in the accommodating cavities, second magnets are arranged on the side surfaces of the pipe fixing pieces, transmission shafts are arranged on the two sides of the Raman spectrum detector, first magnets are respectively connected to the upper ends of the transmission shafts, the magnetism of one of the first magnets is attracted to the magnetism of the second magnet, and the magnetism of the other first magnet is repelled from the magnetism of the second magnet. The application reduces the labor intensity of detection personnel and improves detection efficiency.

Description

Technical Field

[0001] This invention relates to the field of optical detection facilities, and more particularly to a medical Raman spectroscopy detection device. Background Technology

[0002] Raman spectroscopy has shown great promise in medical diagnostics, enabling applications such as evaluating sample morphology and structure, determining pathological changes within cells, tissues, and organs. Different Raman peaks are characteristic of certain molecules, giving Raman spectroscopy the ability to perform qualitative analysis and distinguish similar substances. The peak intensity of a Raman spectrum is proportional to the concentration of the corresponding molecule, allowing for quantitative analysis as well. However, existing Raman spectroscopy detection equipment requires the addition of saline solution to the blood sample and manual shaking by the operator to dilute the sample before detection, a process involving prolonged shaking that significantly increases the workload of the operators. Summary of the Invention

[0003] The purpose of this invention is to address the shortcomings of the prior art by proposing a medical Raman spectroscopy detection device.

[0004] To achieve the above objectives, the technical solution adopted by the present invention is as follows: a medical Raman spectroscopy detection device, comprising a Raman spectrometer, wherein a limiting frame is fixedly installed in the middle of the detection stage of the Raman spectrometer, a tube seat is slidably arranged inside the limiting frame, a positioning element is provided between the tube seat and the limiting frame, a receiving cavity is opened at both ends of the tube seat, a fixed tube component is installed inside the two receiving cavities, a second magnet is installed on the side of the fixed tube component, and a drive shaft is provided on both sides of the Raman spectrometer, wherein two first magnets are respectively connected to the upper end of the drive shaft, wherein the magnetism of one first magnet is attracted to the magnetism of the second magnet, and the magnetism of the other first magnet is repelled by the magnetism of the second magnet.

[0005] Preferably, the positioning component includes a bearing shell fixedly installed at the front end of the limiting frame. The front and rear end faces of the tube seat both extend with guide ridges. The guide ridges penetrate the internal front and rear end faces of the limiting frame and are integrally formed with the tube seat. A limiting post is coaxially provided inside the bearing shell. The two ends of the limiting post penetrate from the two ends of the bearing shell respectively, and the limiting post slides with the bearing shell. The rear end of the limiting post passes through the front end of the limiting frame and the front end of the guide ridge in sequence.

[0006] Preferably, a shell frame is fixedly installed at the lower end of the bearing shell, and the end of the shell frame is fixed to the limiting frame. The front and rear ends of the limiting frame are provided with guide grooves. The guide protrusion is fitted into the interior of the guide groove. The front end of the guide protrusion is symmetrically provided with two limiting holes. The rear end of the limiting post is fitted into the interior of one of the limiting holes. The edge of the limiting hole is set with an oblique side.

[0007] Preferably, a pull ring is fixedly installed at the front end of the limiting post, a push cap is coaxially fixedly installed on the outer surface of the limiting post, the outer surface of the push cap is attached to the inner wall of the bearing shell, a fixing spring is wound around the outer side of the limiting post, the rear end of the fixing spring is fixed to the front end of the push cap, and the front end of the fixing spring is fixed to the inner front end of the bearing shell.

[0008] Preferably, the fixed pipe fitting includes a limiting sleeve that is rotatably installed inside two receiving cavities. A support cap is provided directly below the limiting sleeve, and a positioning magnet is connected to the lower end of the support cap. A limiting magnet is connected to the inner bottom surface of the limiting frame, and the magnetism of the limiting magnet is attracted to the magnetism of the positioning magnet.

[0009] Preferably, a first fixing shell is embedded in the outer surface of the limiting magnet, the lower end of the first fixing shell is fixed to the inner bottom surface of the limiting frame, a second fixing shell is embedded in the outer surface of the positioning magnet, the upper end of the second fixing shell is fixed to the support cap, and multiple connecting frames are fixedly installed in a circular array on the upper end of the support cap. The upper end of the connecting frames is fixed to the limiting sleeve, and the upper edge of the inner surface of the limiting sleeve is inclined.

[0010] Preferably, a second housing is inlaid on the outer surface of the second magnet, and the second housing is fixed to the side of the support cap and the side of one of the connecting brackets. A first housing is inlaid on the outer surface of each of the two first magnets, and a rotating frame is fixedly installed between the two first housings. A connecting sleeve is inlaid through the middle of the rotating frame, and the connecting sleeve is inlaid on the upper end of the transmission shaft.

[0011] Preferably, a shaft bracket is rotatably mounted at the lower end of the drive shaft, an L-shaped bracket is fixedly mounted on the side of the shaft bracket, a motor bracket is fixedly mounted at the end of the L-shaped bracket, the motor bracket is fixed to the side of the Raman spectrometer, a servo motor is fixedly mounted at the end of the motor bracket, a drive shaft is coaxially fixedly mounted at the output end of the servo motor, the drive shaft is rotatably mounted through the end of the shaft bracket, a small gear is coaxially rotatably mounted at the upper end of the drive shaft, a large gear is coaxially fixedly mounted at the middle of the outer surface of the drive shaft, the large gear meshes with the small gear, a reinforcing bracket is fixedly mounted at the corner of the L-shaped bracket, limit ears are provided on both sides of the limiting sleeve, an ear bracket is inlaid at the upper end of the limiting ear, the end of the ear bracket is fixed to the inner surface of the receiving cavity, and the lower end of the limiting ear is inclined.

[0012] Compared with the prior art, the present invention has the following beneficial effects: 1. The rotating drive shaft drives two No. 1 magnets on the transmission shaft to rotate via a small gear and a large gear, continuously changing the position of the two No. 1 magnets. Under the attraction and repulsion of the magnets No. 2, the two No. 1 magnets continuously attract and repel the magnets No. 2, causing the test tube in the limiting sleeve to swing left and right under the magnetic force, thus shaking and mixing the blood sample and saline solution in the test tube. This process does not require manual shaking by the testing personnel, effectively reducing the labor intensity of the testing personnel.

[0013] 2. Furthermore, under the action of the tube seat, two test tubes can be loaded simultaneously, so that when one is being tested, the other can simultaneously shake and mix the sample inside the test tube. After one test tube is tested, the pulling ring can be pulled directly to pull the limiting post pushed out by the fixing spring from the limiting hole. Then the tube seat can be pushed, and the guide protrusion slides in the guide groove to assist the tube seat in moving to move the other test tube to the testing position for testing. Afterward, the tested test tube can be taken out and replaced with another test tube to be tested for pre-testing preparation. This cycle is repeated to achieve the purpose of continuous testing, thereby improving testing efficiency. Attached Figure Description

[0014] Figure 1 This is a schematic diagram of the structure of a medical Raman spectroscopy detection device according to the present invention; Figure 2 This is a schematic diagram of the limiting frame of a medical Raman spectroscopy detection device according to the present invention; Figure 3 This is a schematic diagram of the test tube section of a medical Raman spectroscopy detection device according to the present invention; Figure 4 This is a schematic diagram of the limiting ear of a medical Raman spectroscopy detection device according to the present invention; Figure 5 This is a schematic diagram of the servo motor of a medical Raman spectroscopy detection device according to the present invention; Figure 6 This is a cross-sectional view of the carrier shell of a medical Raman spectroscopy detection device according to the present invention.

[0015] In the diagram: 1. Raman spectrometer; 2. Limiting frame; 3. Bearing shell; 4. Guide ridge; 5. Servo motor; 6. Motor frame; 7. L-shaped frame; 8. Shaft frame; 9. Pinion; 10. Drive shaft; 11. Transmission shaft; 12. Rotating frame; 13. Shell No. 1; 14. Magnet No. 1; 15. Large gear; 16. Limiting post; 17. Pulling ring; 18. Fixing spring; 19. Push cap; 20. Limiting hole; 21. Shell frame; 22. Limiting ear; 23. Ear holder; 24. Receiving cavity; 25. Tube seat; 26. Test tube; 27. Guide groove; 28. Fixed shell No. 1; 29. ​​Limiting magnet; 30. Positioning magnet; 31. Magnet No. 2; 32. Shell No. 2; 33. Fixed shell No. 2; 34. Support cap; 35. Connecting frame; 36. Limiting sleeve; 37. Reinforcing frame; 38. Connecting sleeve. Detailed Implementation

[0016] The following description is intended to disclose the invention and enable those skilled in the art to implement it. The preferred embodiments described below are merely examples, and other obvious variations will occur to those skilled in the art.

[0017] like Figures 1-6 The illustrated medical Raman spectroscopy detection device includes a Raman spectrometer 1. The Raman spectrometer 1 is existing technology and widely used; therefore, its specific structure is not described in detail here. A limiting frame 2 is fixedly installed in the middle of the detection stage of the Raman spectrometer 1. The limiting frame 2 supports the tube seat 25. The tube seat 25 is slidably arranged inside the limiting frame 2. A positioning element is provided between the tube seat 25 and the limiting frame 2. The tube seat 25 loads the test tube 26. Receiving cavities 24 are opened at both ends of the tube seat 25. A tube fixing component is installed inside each of the two receiving cavities 24. A second magnet 31 is installed on the side of the tube fixing component. Both sides of the 1 are provided with drive shafts 11, which drive two No. 1 magnets 14 to rotate. The upper end of the drive shaft 11 is connected to two No. 1 magnets 14 respectively. The magnetism of one No. 1 magnet 14 is attracted to the magnetism of No. 2 magnet 31, and the magnetism of the other No. 1 magnet 14 is repelled by the magnetism of No. 2 magnet 31. Under the attraction and repulsion of the magnetism of the two No. 1 magnets 14 and No. 2 magnet 31 respectively, the magnetism of the two No. 1 magnets 14 can continuously attract and repel the magnetism of No. 2 magnet 31, so that the test tube 26 in the limiting sleeve 36 can continuously swing left and right under the magnetic force, so as to shake and mix the blood sample and saline in the test tube 26.

[0018] The positioning component includes a bearing shell 3 fixedly installed at the front end of the limiting frame 2. The bearing shell 3 supports the limiting post 16. The front and rear ends of the tube seat 25 are both extended with guide ridges 4. The guide ridges 4 penetrate the front and rear ends of the limiting frame 2 and serve as guides. The guide ridges 4 are integrally formed with the tube seat 25. The limiting post 16 is coaxially arranged inside the bearing shell 3. The two ends of the limiting post 16 penetrate from the two ends of the bearing shell 3 respectively, and the limiting post 16 and the bearing shell 3 are slidably engaged. The rear end of the limiting post 16 passes through the front end of the limiting frame 2 and the front end of the guide ridge 4 in sequence. The limiting post 16 can limit and fix the tube seat 25, so that the test tube 26 on the tube seat 25 can be located directly below the detection end of the Raman spectrometer 1 for detection.

[0019] A frame 21 is fixedly installed at the lower end of the bearing shell 3. The end of the frame 21 is fixed to the limiting frame 2. The frame 21 serves to fix the bearing shell 3. The front and rear ends of the limiting frame 2 are provided with guide grooves 27. The guide protrusion 4 fits into the inside of the guide groove 27. The guide groove 27 plays a role in cooperating with the guide protrusion 4. The front end of the guide protrusion 4 is symmetrically provided with two limiting holes 20. The rear end of the limiting post 16 fits into the inside of one of the limiting holes 20. The limiting hole 20 plays a role in cooperating with the limiting post 16. The edge of the limiting hole 20 is set with a bevel to facilitate the insertion of the limiting post 16.

[0020] A pull ring 17 is fixedly installed at the front end of the limiting post 16. The pull ring 17 facilitates the pulling of the limiting post 16. A push cap 19 is coaxially fixedly installed on the outer surface of the limiting post 16. The outer surface of the push cap 19 is attached to the inner wall of the bearing shell 3. A fixing spring 18 is wound around the outer side of the limiting post 16. The push cap 19 is pushed by the fixing spring 18. The rear end of the fixing spring 18 is fixed to the front end of the push cap 19. The front end of the fixing spring 18 is fixed to the inner front end of the bearing shell 3. The fixing spring 18 pushes the limiting post 16 into the limiting hole 20.

[0021] The fixed tube fitting includes a limiting sleeve 36 that is rotatably installed inside the two receiving cavities 24. A support cap 34 is provided directly below the limiting sleeve 36. The limiting sleeve 36 serves to limit the test tube 26. A positioning magnet 30 is connected to the lower end of the support cap 34. The support cap 34 serves to support the test tube 26. A limiting magnet 29 is connected to the inner bottom surface of the limiting frame 2. The magnetism of the limiting magnet 29 is attracted to the magnetism of the positioning magnet 30. The limiting magnet 29 and the positioning magnet 30 serve to keep the test tube 26 in an upright state.

[0022] The outer surface of the limiting magnet 29 is inlaid with a first fixing shell 28. The lower end of the first fixing shell 28 is fixed to the inner bottom surface of the limiting frame 2. The first fixing shell 28 serves to fix the limiting magnet 29. The outer surface of the positioning magnet 30 is inlaid with a second fixing shell 33. The second fixing shell 33 serves to fix the positioning magnet 30. The upper end of the second fixing shell 33 is fixed to the cap 34. The upper end of the cap 34 is fixedly installed with multiple connecting frames 35 in a circular array. The upper end of the connecting frames 35 is fixed to the limiting sleeve 36. The connecting frames 35 serve to connect the limiting sleeve 36 and the cap 34. The inner upper edge of the limiting sleeve 36 is inclined to facilitate the insertion of the test tube 26.

[0023] The outer surface of the second magnet 31 is inlaid with a second housing 32. The second housing 32 is fixed to the side of the cap 34 and the side of one of the connecting brackets 35. The second housing 32 serves to fix the second magnet 31. The outer surfaces of the two first magnets 14 are each inlaid with a first housing 13. The first housing 13 serves to fix the first magnet 14. A rotating frame 12 is fixedly installed between the two first housings 13. A connecting sleeve 38 is inlaid through the middle of the rotating frame 12. The rotating frame 12 and the connecting sleeve 38 serve to connect the first magnet 14 and the drive shaft 11 together. The connecting sleeve 38 is inlaid at the upper end of the drive shaft 11.

[0024] A shaft bracket 8 is rotatably mounted on the lower end of the drive shaft 11. An L-shaped bracket 7 is fixedly mounted on the side of the shaft bracket 8. The shaft bracket 8 serves to support the drive shaft 11 and the drive shaft 10. A motor bracket 6 is fixedly mounted on the end of the L-shaped bracket 7. The motor bracket 6 is fixed to the side of the Raman spectrometer 1. A servo motor 5 is fixedly mounted on the end of the motor bracket 6. The motor bracket 6 serves to fix the servo motor 5. A drive shaft 10 is coaxially fixedly mounted on the output end of the servo motor 5. The drive shaft 10 is rotatably mounted through the end of the shaft bracket 8. A small gear 9 is coaxially rotatably mounted on the upper end of the drive shaft 10. A large gear 15 is coaxially fixedly mounted on the middle of the outer surface of the drive shaft 11. 15 meshes with the small gear 9, and the large gear 15 plays a transmission role with the small gear 9. A reinforcing frame 37 is fixedly installed at the corner of the L-shaped frame 7. The reinforcing frame 37 plays a role in improving the load-bearing strength of the L-shaped frame 7. Limiting ears 22 are provided on both sides of the limiting sleeve 36. The upper end of the limiting ear 22 is inlaid with an ear bracket 23. The ear bracket 23 plays a role in fixing the limiting ear 22. The limiting ear 22 plays a role in limiting the swing amplitude of the test tube 26. The end of the ear bracket 23 is fixed to the inner surface of the receiving cavity 24. The lower end of the limiting ear 22 is inclined so as to fit and adapt to the end face of the connecting frame 35 after swinging, so that the connecting frame 35 and the limiting ear 22 can make full contact.

[0025] During testing, test tube 26 is inserted into limiting sleeve 36. At this time, cap 34 is attached to the bottom of test tube 26 to limit and support it. Then, servo motor 5 drives drive shaft 10 to rotate, which in turn drives two magnets 14 on transmission shaft 11 via pinion 9 and gear 15 to rotate. This continuously changes the position of the two magnets 14, so that the magnets 14 attract and repel magnets 31, causing the magnets 14 to continuously attract and repel magnets 31. This magnetic force causes test tube 26 in limiting sleeve 36 to swing left and right, mixing the blood sample and saline solution inside. Then, pull ring 17 is pulled to... The limiting post 16, pushed out by the fixed spring 18, is pulled out from the limiting hole 20 and then pushes the tube seat 25. At this time, the guide ridge 4 slides in the guide groove 27 to assist the tube seat 25 in moving so as to send the test tube 26 to the detection position. At this time, the limiting magnet 29 and the positioning magnet 30 attract each other, keeping the test tube 26 in an upright state. Then, the detection end of the Raman spectrometer 1 emits detection light to detect the blood sample in the test tube 26. During this process, another test tube 26 to be tested can be placed in the limiting sleeve 36 at the other end of the tube seat 25 to shake the test tube 26, which is to prepare for the test. After the previous test tube 26 has been tested, the test tube 26 can be directly pushed to the detection position for testing. This cycle is repeated continuously.

[0026] The foregoing has shown and described the basic principles, main features, and advantages of the present invention. Those skilled in the art should understand that the present invention is not limited to the above embodiments. The embodiments and descriptions in the specification are merely principles of the invention. Various changes and modifications can be made to the invention without departing from its spirit and scope, and all such changes and modifications fall within the scope of the claimed invention. The scope of protection claimed by the appended claims and their equivalents is defined.

Claims

1. A medical Raman spectroscopy detection device, comprising a Raman spectrometer (1), characterized in that: The Raman spectrometer (1) has a limiting frame (2) fixedly installed in the middle of the detection stage. A tube seat (25) is slidably arranged inside the limiting frame (2). A positioning component is provided between the tube seat (25) and the limiting frame (2). Both ends of the tube seat (25) are provided with receiving cavities (24). A fixed tube component is installed inside the two receiving cavities (24). A second magnet (31) is installed on the side of the fixed tube component. Both sides of the Raman spectrometer (1) are provided with drive shafts (11). The upper end of the drive shafts (11) is connected to two first magnets (14). The magnetism of one of the first magnets (14) is attracted to the magnetism of the second magnet (31), and the magnetism of the other first magnet (14) is repelled by the magnetism of the second magnet (31).

2. The medical Raman spectroscopy detection device according to claim 1, characterized in that: The positioning component includes a bearing shell (3) fixedly installed at the front end of the limiting frame (2). The front and rear ends of the tube seat (25) are both extended with guide ridges (4). The guide ridges (4) penetrate the front and rear ends of the limiting frame (2). The guide ridges (4) are integrally formed with the tube seat (25). The bearing shell (3) is coaxially provided with a limiting post (16). The two ends of the limiting post (16) penetrate from the two ends of the bearing shell (3) respectively. The limiting post (16) and the bearing shell (3) are slidably engaged. The rear end of the limiting post (16) penetrates the front end of the limiting frame (2) and the front end of the guide ridge (4) in sequence.

3. The medical Raman spectroscopy detection device according to claim 2, characterized in that: The lower end of the bearing shell (3) is fixedly installed with a shell frame (21). The end of the shell frame (21) is fixed with the limiting frame (2). The front and rear end faces of the limiting frame (2) are provided with guide grooves (27). The guide protrusion (4) fits into the interior of the guide groove (27). The front end face of the guide protrusion (4) is symmetrically provided with two limiting holes (20). The rear end of the limiting post (16) fits into the interior of one of the limiting holes (20). The edge of the limiting hole (20) is set with an oblique edge.

4. The medical Raman spectroscopy detection device according to claim 2, characterized in that: A pull ring (17) is fixedly installed at the front end of the limiting post (16). A push cap (19) is coaxially fixedly installed on the outer surface of the limiting post (16). The outer surface of the push cap (19) is attached to the inner wall of the bearing shell (3). A fixing spring (18) is wound around the outer side of the limiting post (16). The rear end of the fixing spring (18) is fixed to the front end of the push cap (19). The front end of the fixing spring (18) is fixed to the inner front end of the bearing shell (3).

5. The medical Raman spectroscopy detection device according to claim 1, characterized in that: The fixed pipe fitting includes a limiting sleeve (36) that is rotatably installed inside two receiving cavities (24). A support cap (34) is provided directly below the limiting sleeve (36). A positioning magnet (30) is connected to the lower end of the support cap (34). A limiting magnet (29) is connected to the inner bottom surface of the limiting frame (2). The magnetism of the limiting magnet (29) is attracted to the magnetism of the positioning magnet (30).

6. The medical Raman spectroscopy detection device according to claim 5, characterized in that: The outer surface of the limiting magnet (29) is inlaid with a first fixing shell (28), the lower end of the first fixing shell (28) is fixed to the inner bottom surface of the limiting frame (2), the outer surface of the positioning magnet (30) is inlaid with a second fixing shell (33), the upper end of the second fixing shell (33) is fixed to the cap (34), the upper end of the cap (34) is fixedly installed with multiple connecting frames (35) in a ring array, the upper end of the connecting frame (35) is fixed to the limiting sleeve (36), and the upper edge of the inner side of the limiting sleeve (36) is inclined.

7. The medical Raman spectroscopy detection device according to claim 6, characterized in that: The outer surface of the second magnet (31) is inlaid with a second housing (32). The second housing (32) is fixed to the side of the cap (34) and the side of one of the connecting frames (35). The outer surfaces of the two first magnets (14) are inlaid with a first housing (13). A rotating frame (12) is fixedly installed between the two first housings (13). A connecting sleeve (38) is inlaid through the middle of the rotating frame (12). The connecting sleeve (38) is inlaid at the upper end of the transmission shaft (11).

8. A medical Raman spectroscopy detection device according to claim 7, characterized in that: A shaft bracket (8) is rotatably mounted on the lower end of the drive shaft (11). An L-shaped bracket (7) is fixedly mounted on the side of the shaft bracket (8). A motor bracket (6) is fixedly mounted on the end of the L-shaped bracket (7). The motor bracket (6) is fixed to the side of the Raman spectrometer (1). A servo motor (5) is fixedly mounted on the end of the motor bracket (6). A drive shaft (10) is coaxially fixedly mounted on the output end of the servo motor (5). The drive shaft (10) is rotatably mounted through the end of the shaft bracket (8). The upper end of the drive shaft (10) is... A small gear (9) is coaxially mounted on the transmission shaft (11). A large gear (15) is coaxially fixed on the middle of the outer surface of the transmission shaft (11). The large gear (15) meshes with the small gear (9). A reinforcing frame (37) is fixedly mounted at the corner of the L-shaped frame (7). Limiting ears (22) are provided on both sides of the limiting sleeve (36). An ear frame (23) is inlaid at the upper end of the limiting ear (22). The end of the ear frame (23) is fixed to the inner surface of the receiving cavity (24). The lower end of the limiting ear (22) is inclined.

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