Pharmaceutical centrifugal filter device

Abstract

The application discloses a centrifugal filtering device for pharmacy, which comprises a fixed seat, a filtering mechanism is arranged in the fixed seat, the filtering mechanism comprises a filter barrel, a rotating rod is fixedly connected to the outer surface of the filter barrel, the filter barrel rotates along the center of the fixed seat, a filter paper is arranged in the filter barrel, a fixed cover is fixedly connected to the open end of the filter barrel, a fixed sleeve is arranged outside the filter barrel, and a connecting sleeve is arranged outside the fixed sleeve, and belongs to the technical field of centrifugal filters. The centrifugal filtering device solves the problems that, when the centrifugal filtering device is used, solid-liquid separation is carried out through collision kinetic energy, the crystallization is easily reduced, the collection difficulty is increased, internal blockage and cleaning are difficult, spiral feeding and filtering are simultaneously carried out, the contact range of the crystallization in the internal part is enlarged, and the actual feeding effect, the crystallization collection efficiency and effect are poor.

Description

Technical Field

[0001] This invention relates to the field of centrifugal filtration technology, specifically to a pharmaceutical centrifugal filtration device. Background Technology

[0002] In many pharmaceutical raw material preparation processes, it is necessary to pass the crystallized material and solution together into a centrifugal filter for centrifugal filtration to achieve solid-liquid separation. Therefore, the performance requirements of the motor that provides centrifugal force are high. In the invention patent with publication number CN115646035A, a pharmaceutical centrifugal filtration device is disclosed, which includes a base box and a sealed outer cover. Through the structural design of the internal cavity of the centrifugal spraying plate, the sprayed crystallized drug liquid obtains sufficient kinetic energy and acts on the filter cylinder to achieve centrifugal separation. At the same time, it also realizes the real-time unblocking of the filter holes on the filter cylinder without the need for shutdown maintenance.

[0003] Although this device has the advantages mentioned above, it still has the following drawbacks in practical use: 1) This device essentially separates solids and liquids through the collision kinetic energy between the solution and the filter cartridge. This not only easily leads to smaller crystal volume, increasing the difficulty of collection, but also fails to consider the problems of clogging and cleaning inside the spraying plate. 2) When the device is working, it filters and conveys material by a spiral at the same time. This results in poor material conveying effect and increased contact area of ​​crystals inside, which increases the difficulty of collection and reduces collection efficiency and effect.

[0004] Therefore, it is necessary to address the existing problems with existing centrifugal filtration devices. Summary of the Invention

[0005] To address the shortcomings of existing technologies, this invention provides a pharmaceutical centrifugal filtration device that solves the problems of existing centrifugal filtration devices, which rely on collision kinetic energy for solid-liquid separation, leading to smaller crystals and increased collection difficulty, as well as internal blockage and difficulty in cleaning. Furthermore, the simultaneous operation of spiral conveying and filtration expands the contact range of crystals inside the device, resulting in poor actual conveying efficiency, crystal collection efficiency, and overall effectiveness.

[0006] To achieve the above objectives, the present invention provides the following technical solution: a pharmaceutical centrifugal filtration device, comprising a fixed base, a circulating filtration mechanism inside the fixed base, the circulating filtration mechanism including a filter barrel, a rotating rod fixedly connected to the outer surface of the filter barrel, the filter barrel rotating around the center of the fixed base, filter paper inside the filter barrel, a fixed cover fixedly connected to the open end of the filter barrel, a fixed sleeve fitted outside the filter barrel, a connecting sleeve fitted outside the fixed sleeve, one end of the rotating rod being rotatably connected to the body of the fixed sleeve and the connecting sleeve in sequence and extending to the outside of the connecting sleeve, the outer surface of the fixed sleeve being fixedly connected to the inside of the connecting sleeve by an arc block, a connecting pipe penetrating through the inside of the fixed sleeve, one end of the connecting pipe being connected to the inside of the connecting sleeve, a gear fixedly connected to the outer surface of the rotating rod, a gear meshing with a toothed ring on the outer surface of the gear, the outer surface of the toothed ring being fixedly connected to the inside of the fixed base by a fixed rod, one end of the fixed cover being connected to a fixed pipe, the fixed pipe having two sections, upper and lower, for respectively realizing loading and unloading, the outer surfaces of both fixed pipes being fixedly connected to the body of the fixed base.

[0007] Preferably, a rotary cylinder is fixedly connected inside the fixed base, and a rotating plate is fixedly connected to the output end of the rotary cylinder. The outer surface of the rotating plate is rotatably connected to the inside of the fixed base. The toothed ring is sleeved on the outside of the rotating plate. The outer surface of the rotating plate has a cut surface at an equal angle. One end of the rotating rod is embedded and rotatably connected to the outer surface of the cut surface. The outer surface of the sleeve is fixedly connected to the outer surface of the cut surface through a fixed column.

[0008] Preferably, the filter barrel is provided with a cleaning component, which includes a sliding cavity. The sliding cavity is opened inside the rotating rod. A sliding rod is slidably connected inside the sliding cavity. One end of the sliding rod is slidably connected to the rotating rod and the filter barrel body in sequence and extends into the filter barrel. A push plate is fixedly connected to one end of the sliding rod. The outer surface of the push plate is movably connected to the outer surface of the filter paper.

[0009] Preferably, a limiting groove is formed inside the sliding cavity, and a magnetic plate is slidably connected inside the limiting groove. The outer surface of the magnetic plate is fixedly connected to the other end of the sliding rod. An electromagnet is movably connected to the outside of the magnetic plate by magnetic force, and the outer surface of the electromagnet is fixedly connected to the inside of the sliding cavity.

[0010] Preferably, a vibrating material assembly is provided on the outside of the fixed sleeve. The vibrating material assembly includes a flexible plate. The outer surface of the flexible plate is fixedly connected to the outer surface of the fixed sleeve. A drive motor is provided on the outside of the flexible plate. A rotating bar is provided on the outside of the output end of the drive motor. The outer surface of the rotating bar abuts against the outer surface of the flexible plate. A support plate is fixedly connected to the outer surface of the drive motor. The outer surface of the support plate is fixedly connected to the inside of the fixed base through a telescopic rod.

[0011] Preferably, the output end of the drive motor is fixedly connected to a retainer, and the outer surface of the retainer is provided with a retaining groove at an equal angle. One end of the rotating bar is engaged with the inside of the retaining groove. A baffle is movably connected to the outer surface of the retainer, and the outer surface of the baffle abuts against the outer surface of the rotating bar. A bolt is movably connected through the body of the baffle, and one end of the bolt is threadedly connected to the outer surface of the retainer.

[0012] Preferably, an auxiliary vibration unit is provided on the outside of the rigid plate. The auxiliary vibration unit includes a fixed plate, which is fixed at an equal angle inside the base. An inner cavity is opened inside the fixed plate, and a stop plate is slidably connected inside the inner cavity. One end of the stop plate is slidably connected through the body of the fixed plate and extends into the interior of the base. The outer surface of the stop plate abuts against the outer surface of the rigid plate.

[0013] Preferably, a connecting bar is fixedly connected to the other end of the abutment, the outer surface of the connecting bar is slidably connected to the inside of the inner cavity, a spring rod is fixedly connected to the outer surface of the connecting bar, one end of the spring rod is fixedly connected to the inside of the inner cavity, and an air inlet pipe and an exhaust pipe are respectively connected through the two sides of the inside of the inner cavity.

[0014] Beneficial effects This invention provides a pharmaceutical centrifugal filtration device. Compared with the prior art, it has the following advantages: (1) By setting up a circulating filter mechanism, the connection between two solid pipes and a solid cover is used to realize the feeding of the solution and the discharge of the crystals. At the same time, the rotating cylinder drives the filter barrel to rotate through the rotating plate. During this process, the filter barrel rotates by the meshing of gears and gear rings, thereby using centrifugal force to separate the solid and liquid. The crystals are stored inside the filter barrel by the action of filter paper and discharged. At the same time, the cooperation of the solid sleeve and the connecting sleeve can prevent the filtered solution from splashing inside the solid base. This circulating step can realize continuous filtration and separation, which not only improves the collection efficiency and effect, but also avoids the problems of internal blockage and difficulty in cleaning.

[0015] (2) By setting up a cleaning component, when the solid cover is connected to the solid pipe below for crystal discharge, if there are some crystals that cannot be discharged in time, the electromagnet is energized to generate magnetism, and the magnetic repulsion between the electromagnet and the magnetic plate causes the magnetic plate to slide inside the filter barrel through the sliding rod. Thus, through the contact between the push plate and the filter paper, all crystals are scraped off and discharged through the guiding effect of the solid cover, thereby improving the collection efficiency and effect. In addition, the repeated action of magnetic attraction and repulsion can also avoid the problem of stubborn adhesion of crystals.

[0016] (3) By setting up a vibrating material assembly, when the solid cover is connected to the lower solid pipe to solve the material discharge, the output end of the telescopic rod extends so that the drive motor drives the rotating bar to move and contact the ductile plate. Then the drive motor drives the rotating bar to rotate so as to deform the ductile plate by abutting. Thus, the filter barrel vibrates through the solid sleeve and the rotating rod to accelerate the discharge of crystallized material and avoid the problem of crystallization adhering to the filter paper. Furthermore, by controlling the extension and retraction of the telescopic rod and the number of rotating bars, the vibration frequency and amplitude of the ductile plate can be adjusted, which makes it easier to discharge the crystallized material.

[0017] (4) By setting up an auxiliary vibration unit, when the rotating plate drives the filter barrel to rotate inside the fixed seat, the ductile plate deforms by contacting the abutment plate, so that when the filter barrel rotates for centrifugal filtration, the crystals are prevented from caking or stubbornly adhering to the filter paper, which facilitates the discharge of the crystals after filtration. At the same time, by controlling the air pressure inside the cavity, and by the action of air pressure and spring rod elasticity, the amplitude of the ductile plate is controlled by adjusting the extension length of the abutment plate, thereby avoiding fatigue damage to the filter barrel and rotating rod, and can be adapted to the amount of crystals for auxiliary vibration. Attached Figure Description

[0018] Figure 1 This is a perspective view of the internal structure of the mounting base of the present invention; Figure 2 This is a perspective view of the internal structure of the nested structure of the present invention; Figure 3 This is a perspective view of the external structure of the rotating plate of the present invention; Figure 4 This is a perspective view of the internal structure of the rotating rod of the present invention; Figure 5 This is a perspective view of the external structure of the card holder of the present invention; Figure 6 This is a three-dimensional view of the internal structure of the fixed plate of the present invention.

[0019] In the diagram: 1. Fixed base; 2. Filter barrel; 3. Rotating rod; 4. Cleaning assembly; 41. Sliding cavity; 42. Sliding rod; 43. Push plate; 44. Limiting groove; 45. Magnetic plate; 46. Electromagnet; 5. Filter paper; 6. Fixed cover; 7. Vibrating assembly; 71. Tough plate; 72. Auxiliary vibration unit; 721. Fixed plate; 722. Inner cavity; 723. Support plate; 724. Connecting bar; 725. Spring rod; 726. Inlet 727. Air pipe; 73. Exhaust pipe; 74. Drive motor; 75. Rotary bar; 76. Support plate; 77. Telescopic rod; 78. Card seat; 79. Card slot; 710. Baffle; 8. Bolt; 9. Fixed sleeve; 10. Arc block; 11. Gear; 12. Gear ring; 13. Fixed rod; 14. Fixed pipe; 15. Rotary cylinder; 16. Rotating plate; 17. Cut surface; 18. Fixed column; 19. Connecting pipe. Detailed Implementation

[0020] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0021] Please see Figure 1-6 This invention provides a technical solution: a pharmaceutical centrifugal filtration device. The system includes a base 1, which has a circular interior. Inside the base 1 is a circulating filtration mechanism, including a filter barrel 2. Filter holes are formed on the outer arc surface of the filter barrel 2 to facilitate solution filtration and discharge. A rotating rod 3 is fixedly connected to the outer surface of the filter barrel 2, allowing it to rotate around the center of the base 1. Filter paper 5 is installed inside the filter barrel 2 to further enhance filtration performance, improving crystal collection efficiency and effectiveness. A funnel-shaped cover 6 is fixedly connected to the open end of the filter barrel 2 to facilitate solution feeding and to collect and guide the discharged crystals. An external fixed sleeve 8 is provided, which prevents the solution from splashing when the filter barrel 2 rotates. When the opening of the fixed sleeve 8 faces downward, it can guide and discharge the filtered solution. An external connecting sleeve 9 is provided outside the fixed sleeve 8, which provides double protection. When the opening of the filter barrel 2 faces upward, the filtered solution enters the interior of the connecting sleeve 9 through the fixed sleeve 8, which can prevent backflow from affecting the filtration effect and efficiency. One end of the rotating rod 3 is rotatably connected to the body of the fixed sleeve 8 and the connecting sleeve 9 in sequence and extends to the outside of the connecting sleeve 9. The outer surface of the fixed sleeve 8 and the interior of the connecting sleeve 9 are fixedly connected by an arc block 10, which acts as a fixed sleeve. The fixed connection between the fixed sleeve 8 and the connecting sleeve 9 is achieved by a connecting pipe 19 running through the interior of the fixed sleeve 8. The connecting pipe 19 is made of a one-way valve, allowing the solution inside the fixed sleeve 8 to flow unidirectionally into the connecting sleeve 9 when the opening of the fixed sleeve 8 is facing upwards. One end of the connecting pipe 19 is connected to the interior of the connecting sleeve 9. A gear 11 is fixedly connected to the outer surface of the rotating rod 3, and a toothed ring 12 meshes with the outer surface of the gear 11. The gear 11 and the toothed ring 12 use bevel gear vertical transmission, and the rotation speed of the filter bucket 2 and the magnitude of the centrifugal force generated are controlled by setting the outer diameter of the gear 11. The outer surface of the toothed ring 12 is connected to the fixed base 1 via the fixed rod 13. The internal fixed connection is such that one end of the fixed cover 6 is connected to a fixed tube 14. The fixed tube 14 is provided with two parts, upper and lower, to realize the feeding and unloading of materials respectively. The upper fixed tube 14 is connected to the external feeding device for the function of feeding solution, and the lower fixed tube 14 is used for crystallization discharge. At the same time, the body of the fixed base 1 has a discharge port with an inner diameter larger than the outer diameter of the fixed tube 14 and is through it for discharging the filtered solution. The discharge port is coaxially arranged with the lower fixed tube 14. A filter screen is fixedly connected through the lower fixed tube 14 and is fixedly connected to the inside of the discharge port. The outer surfaces of both fixed tubes 14 are fixedly connected through the body of the fixed base 1.

[0022] A rotary cylinder 15 is fixedly connected inside the base 1. The rotary cylinder 15 is equipped with waterproof measures and is connected to an external control circuit. A rotating plate 16 is fixedly connected to the output end of the rotary cylinder 15. The outer surface of the rotating plate 16 is rotatably connected to the inside of the base 1. A toothed ring 12 is sleeved on the outside of the rotating plate 16. The outer surface of the rotating plate 16 has cut surfaces 17 at equal angles. The number of cut surfaces 17 is even, so that the two sets of filter barrels 2 that are mirror symmetrical can be fed and crystallized at the same time. One end of the rotating rod 3 is embedded and rotatably connected to the outer surface of the cut surface 17. The outer surface of the connecting sleeve 9 is fixedly connected to the outer surface of the cut surface 17 through a fixed column 18. The fixed column 18 plays a role in fixing the fixed sleeve 8 and the connecting sleeve 9, so as to support the filter barrel 2.

[0023] The filter barrel 2 is equipped with a cleaning component 4, which includes a sliding cavity 41. The sliding cavity 41 is opened inside the rotating rod 3. A sliding rod 42 is slidably connected inside the sliding cavity 41. The outer diameter of the sliding rod 42 is adapted to the inner diameter of the sliding cavity 41. One end of the sliding rod 42 is slidably connected to the rotating rod 3 and the body of the filter barrel 2 in sequence and extends into the interior of the filter barrel 2. A push plate 43 is fixedly connected to one end of the sliding rod 42. The push plate 43 is made of a material that is pressure-resistant, wear-resistant, corrosion-resistant and has good sealing performance. It can scrape and push the crystals that are not discharged in time inside the filter barrel 2. The outer surface of the push plate 43 is movably connected to the outer surface of the filter paper 5.

[0024] A limiting groove 44 is provided inside the sliding cavity 41. A magnetic plate 45 is slidably connected inside the limiting groove 44. The magnetic plate 45 is a permanent magnet with a rectangular shape, which is adapted to the size of the limiting groove 44. It can limit the movement of the push plate 43 and improve the radial stability of the push plate 43. At the same time, the attraction force generated by the magnetic plate 45 is greater than the centrifugal force of the rotating plate 16. The outer surface of the magnetic plate 45 is fixedly connected to the other end of the sliding rod 42. An electromagnet 46 is movably connected to the outside of the magnetic plate 45 by magnetic force. The electromagnet 46 is electrically connected to the external control circuit through a rotating connecting element. The rotating connecting element is respectively set on the rotating rod 3 and the rotating plate 16. The outer surface of the electromagnet 46 is fixedly connected to the inside of the sliding cavity 41.

[0025] The outer side of the fixed sleeve 8 is provided with a vibrating material assembly 7, which includes a rigid plate 71. The rigid plate 71 is made of a material that is pressure-resistant, wear-resistant, fatigue-resistant, corrosion-resistant, and has good toughness. It generates vibration through its own deformation so that the filter barrel 2 vibrates accordingly, thereby facilitating centrifugal filtration and discharge of crystallized material. The outer surface of the rigid plate 71 is fixedly connected to the outer surface of the fixed sleeve 8. A drive motor 73 is provided on the outer side of the rigid plate 71. The drive motor 73 is equipped with waterproof measures and is electrically connected to an external control circuit. A rotating bar 74 is provided on the outer side of the output end of the drive motor 73. The rotating bar 74 is made of a material that is pressure-resistant, wear-resistant, corrosion-resistant, and has high hardness. The outer surface of the rotating bar 74 abuts against the outer surface of the rigid plate 71. A support plate 75 is fixedly connected to the outer surface of the drive motor 73. The outer surface of the support plate 75 is fixedly connected to the interior of the fixed base 1 through a telescopic rod 76. The telescopic rod 76 is made of an electric push rod and is electrically connected to an external control circuit.

[0026] The output end of the drive motor 73 is fixedly connected to a retainer 77. The outer surface of the retainer 77 has slots 78 at equal angles. Multiple slots 78 are set at equal angles and are arranged in a T-shape in the top view. At the same time, one end of the rotating bar 74 is also arranged in a T-shape. The two are interlocked to improve the radial stability and lateral force performance of the rotating bar 74, and facilitate the disassembly and assembly of the rotating bar 74. By controlling the number of rotating bars 74, the vibration frequency of the rigid plate 71 can be controlled. One end of the rotating bar 74 is interlocked with the inside of the slot 78. A baffle 79 is movably connected to the outer surface of the retainer 77. The baffle 79 fixes and limits the rotating bar 74. The outer surface of the baffle 79 abuts against the outer surface of the rotating bar 74. A bolt 710 is movably connected through the body of the baffle 79. One end of the bolt 710 is threadedly connected to the outer surface of the retainer 77.

[0027] An auxiliary vibration unit 72 is provided on the outside of the rigid plate 71. The auxiliary vibration unit 72 includes a fixed plate 721, which serves as a fixed support. The fixed plate 721 is fixed at an equal angle inside the base 1. An inner cavity 722 is opened inside the fixed plate 721. The inner cavity 722 is filled with high-pressure gas to control the sliding and relative stability of the abutment plate 723. The abutment plate 723 is slidably connected inside the inner cavity 722. The abutment plate 723 and the rotating bar 74 are made of the same material and play the same role. One end of the abutment plate 723 is slidably connected to the body of the fixed plate 721 and extends into the interior of the base 1. The outer surface of the abutment plate 723 abuts against the outer surface of the rigid plate 71.

[0028] The other end of the abutment 723 is fixedly connected to a connecting bar 724. The connecting bar 724 is made of a material that is pressure-resistant, wear-resistant, and has good sealing properties. At the same time, the cross-sectional dimensions of the connecting bar 724 are adapted to the internal cross-sectional dimensions of the inner cavity 722, which can limit the movement of the abutment 723. The outer surface of the connecting bar 724 is slidably connected to the inside of the inner cavity 722. A spring rod 725 is fixedly connected to the outer surface of the connecting bar 724. The spring rod 725 can guide and limit the movement of the abutment 723, and, in conjunction with high-pressure gas, control the movement distance of the abutment 723, thereby controlling the amplitude of the rigid plate 71. One end of the spring rod 725 is fixedly connected to the inside of the inner cavity 722. An air inlet pipe 726 and an exhaust pipe 727 are respectively connected through the two sides of the inner cavity 722. The air inlet pipe 726 is made of a one-way valve and is connected to an external air pump (not shown in the figure). The exhaust pipe 727 is equipped with a solenoid valve that is electrically connected to an external control circuit to control the discharge of air from the inner cavity 722.

[0029] Furthermore, any content not described in detail in this specification is existing technology known to those skilled in the art.

[0030] This device uses a circulating filtration mechanism as its core, working in conjunction with the cleaning assembly 4, the vibrating assembly 7, and the auxiliary vibration unit 72 to achieve continuous, efficient, and clog-free centrifugal solid-liquid separation of pharmaceutical raw materials. It avoids crystallization, breakage, adhesion, and equipment clogging throughout the process. The complete working principle is as follows: After the device is started, the rotary cylinder 15 inside the fixed base 1 starts to work, driving the rotating plate 16 to rotate at a constant speed around the center of the fixed base 1. The rotating plate 16 drives the connecting sleeve 9, the fixed sleeve 8 and the filter barrel 2 to revolve around the rotating plate 16 through the fixed column 18. At the same time, the gear 11 fixed on the rotating rod 3 and the gear ring 12 fixed on the fixed rod 13 continuously mesh, driving the rotating rod 3 and the filter barrel 2 to rotate at high speed around their own axis during the revolution, forming a compound centrifugal motion of revolution + rotation. The pharmaceutical liquid to be filtered enters from the upper solid pipe 14 and flows into the filter barrel 2 through the solid cover 6. The high-speed rotation of the filter barrel 2 generates a stable centrifugal force. Under the centrifugal action, the liquid in the liquid passes through the filter paper 5 and the filter holes on the wall of the filter barrel 2, enters the solid sleeve 8 outside the filter barrel 2, and then flows into the connecting sleeve 9 through the connecting pipe 19 on the solid sleeve 8. Finally, it is discharged from the pre-set drain port of the solid base 1, completing the solid-liquid separation. The separated solid crystals are intercepted by the filter paper 5 and remain inside the filter barrel 2. This process relies on pure centrifugal force separation, without collision or impact, so as not to cause crystal breakage and avoid blockage of internal channels. Furthermore, the multiple cut surfaces 17 set at equal angles on the rotating plate 16 provide uniform installation positions for multiple sets of filter cartridges 2, enabling multiple sets of filter cartridges 2 to circulate and filter synchronously, greatly improving continuous processing efficiency. When the filter barrel 2 rotates with the rotating plate 16 to the lower unloading position, the solid cover 6 aligns with the lower solid pipe 14 and enters the unloading process. First, natural unloading occurs, with the filter barrel 2 opening downwards. Under the action of gravity and centrifugal residue, the internal crystals are collected and guided by the solid cover 6 and discharged from the lower solid pipe 14. Then, the unloading is assisted by the cleaning component 4. If crystals are attached to the filter paper 5 and cannot fall off naturally, the electromagnet 46 inside the rotating rod 3 is energized to generate magnetism, which generates a repulsive force with the magnetic plate 45, pushing the magnetic plate 45 to slide in the limiting groove 44. The magnetic plate 45 drives the sliding rod 42 to extend outward along the sliding cavity 41, thereby pushing the push plate 43 to slide close to the surface of the filter paper 5, thoroughly scraping and pushing away the residual crystals to ensure that there are no crystal residues. After the cleaning is completed, the magnetic plate 45 drives the push plate 43 to reset under the action of magnetic force, without affecting the next round of filtration. During the crystallization unloading process, the vibrating material assembly 7 is activated simultaneously to enhance the unloading effect and prevent crystal caking. The output end of the telescopic rod 76 extends, driving the support plate 75 and the drive motor 73 to move closer to the ductile plate 71, so that the rotating bar 74 abuts against the surface of the ductile plate 71. The drive motor 73 drives the card holder 77 and the rotating bar 74 to rotate at high speed. The rotating bar 74 continuously pushes the ductile plate 71 to generate elastic deformation and high-frequency vibration. The vibration is transmitted to the filter barrel 2 through the fixed sleeve 8 and the rotating rod 3, causing the filter barrel 2 and the filter paper 5 to vibrate synchronously, loosening the attached crystals, accelerating the crystals to fall, and improving the unloading speed and cleanliness. The rotating bar 74 is engaged with the card seat 77 through the slot 78 and fixed by the baffle 79 and bolt 710. The number of rotating bars 74 can be adjusted according to the crystallization characteristics to change the vibration frequency. The telescopic rod 76 can adjust the telescopic amount to control the contact range between the rotating bar 74 and the rigid plate 71, thereby adjusting the vibration amplitude. The auxiliary vibration unit 72 works continuously throughout the entire operation of the device to prevent crystals from adhering and caking during filtration and unloading. The fixed plate 721 is fixed inside the fixed base 1, and the inner cavity 722 is filled with high-pressure gas through the air inlet pipe 726. Under the combined action of air pressure and the elastic force of the spring rod 725, the connecting bar 724 pushes the abutment plate 723 outward to abut against the flexible plate 71. During the revolution of the filter barrel 2, the flexible plate 71 rotates with the filter barrel 2 and continuously collides and squeezes with the abutment plate 723, generating continuous auxiliary vibration, which is transmitted to the inside of the filter barrel 2, making it difficult for crystals to adhere during filtration and to fall off quickly during unloading. By adjusting the air pressure inside the inner cavity 722 through the exhaust pipe 727, the extension length of the abutment plate 723 can be changed, thereby adjusting the deformation amplitude and vibration intensity of the flexible plate 71 to adapt to crystallization treatment with different particle sizes and different viscosities, while avoiding fatigue damage to the filter barrel 2 and the rotating rod 3 due to excessive vibration. After a set of filter barrels 2 completes filtration, unloading, cleaning, and resetting, it immediately enters the next round of feeding and filtration process with the rotating plate 16. Multiple sets of filter barrels 2 work alternately to achieve uninterrupted and continuous centrifugal filtration. The whole process is free from collision-type separation and spiral conveying interference, resulting in high crystal integrity, high collection efficiency, and easy cleaning of the equipment interior. It completely solves the problems of crystallization breakage, blockage, and difficult unloading in traditional devices.

[0031] Although embodiments of the invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and variations can be made to these embodiments without departing from the principles and spirit of the invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A pharmaceutical centrifugal filtration device, comprising a base (1), characterized in that: The fixed base (1) is equipped with a circulating filtration mechanism, which includes a filter barrel (2). A rotating rod (3) is fixedly connected to the outer surface of the filter barrel (2). The filter barrel (2) rotates around the center of the fixed base (1). Filter paper (5) is installed inside the filter barrel (2). A fixed cover (6) is fixedly connected to the open end of the filter barrel (2). A fixed sleeve (8) is fitted on the outside of the filter barrel (2). A connecting sleeve (9) is fitted on the outside of the fixed sleeve (8). One end of the rotating rod (3) is rotatably connected to the body of the fixed sleeve (8) and the connecting sleeve (9) and extends to the outside of the connecting sleeve (9). The outer surface of the fixed sleeve (8) is connected to the connecting sleeve (9). The interior of the fixed sleeve (8) is fixedly connected by an arc block (10). The interior of the fixed sleeve (8) is connected by a connecting pipe (19). One end of the connecting pipe (19) is connected to the interior of the connecting sleeve (9). The outer surface of the rotating rod (3) is fixedly connected to a gear (11). The outer surface of the gear (11) is meshed with a toothed ring (12). The outer surface of the toothed ring (12) is fixedly connected to the interior of the fixed seat (1) through a fixed rod (13). One end of the fixed cover (6) is connected to a fixed pipe (14). The fixed pipe (14) is provided with two parts, upper and lower, to realize loading and unloading respectively. The outer surfaces of the two fixed pipes (14) are fixedly connected to the body of the fixed seat (1).

2. The pharmaceutical centrifugal filtration device according to claim 1, characterized in that: A rotary cylinder (15) is fixedly connected inside the fixed base (1). A rotating plate (16) is fixedly connected to the output end of the rotary cylinder (15). The outer surface of the rotating plate (16) is rotatably connected to the inside of the fixed base (1). The toothed ring (12) is sleeved on the outside of the rotating plate (16). The outer surface of the rotating plate (16) is provided with a cut surface (17) at equal angles. One end of the rotating rod (3) is embedded and rotatably connected to the outer surface of the cut surface (17). The outer surface of the connecting sleeve (9) is fixedly connected to the outer surface of the cut surface (17) through a fixed column (18).

3. The pharmaceutical centrifugal filtration device according to claim 1, characterized in that: The filter barrel (2) is provided with a cleaning component (4). The cleaning component (4) includes a sliding cavity (41). The sliding cavity (41) is opened inside the rotating rod (3). A sliding rod (42) is slidably connected inside the sliding cavity (41). One end of the sliding rod (42) is slidably connected to the rotating rod (3) and the body of the filter barrel (2) and extends into the interior of the filter barrel (2). One end of the sliding rod (42) is fixedly connected to a push plate (43). The outer surface of the push plate (43) is movably connected to the outer surface of the filter paper (5).

4. A pharmaceutical centrifugal filtration device according to claim 3, characterized in that: The sliding cavity (41) has a limiting groove (44) inside, and a magnetic plate (45) is slidably connected inside the limiting groove (44). The outer surface of the magnetic plate (45) is fixedly connected to the other end of the sliding rod (42). An electromagnet (46) is movably connected to the outside of the magnetic plate (45) by magnetic force. The outer surface of the electromagnet (46) is fixedly connected to the inside of the sliding cavity (41).

5. A pharmaceutical centrifugal filtration device according to claim 1, characterized in that: The outer side of the fixed sleeve (8) is provided with a vibrating material assembly (7), the vibrating material assembly (7) includes a flexible plate (71), the outer surface of the flexible plate (71) is fixedly connected to the outer surface of the fixed sleeve (8), a drive motor (73) is provided on the outer side of the flexible plate (71), a rotating bar (74) is provided on the outer side of the output end of the drive motor (73), the outer surface of the rotating bar (74) abuts against the outer surface of the flexible plate (71), a support plate (75) is fixedly connected to the outer surface of the drive motor (73), and the outer surface of the support plate (75) is fixedly connected to the interior of the fixed base (1) through a telescopic rod (76).

6. A pharmaceutical centrifugal filtration device according to claim 5, characterized in that: The output end of the drive motor (73) is fixedly connected to a card holder (77). The outer surface of the card holder (77) is provided with a slot (78) at equal angles. One end of the rotating bar (74) is engaged with the inside of the slot (78). A baffle (79) is movably connected to the outer surface of the card holder (77). The outer surface of the baffle (79) abuts against the outer surface of the rotating bar (74). A bolt (710) is movably connected through the body of the baffle (79). One end of the bolt (710) is threadedly connected to the outer surface of the card holder (77).

7. A pharmaceutical centrifugal filtration device according to claim 5, characterized in that: An auxiliary vibration unit (72) is provided on the outside of the ductile plate (71). The auxiliary vibration unit (72) includes a fixed plate (721). The fixed plate (721) is fixed at an equal angle inside the base (1). An inner cavity (722) is opened inside the fixed plate (721). A stop plate (723) is slidably connected inside the inner cavity (722). One end of the stop plate (723) is slidably connected to the body of the fixed plate (721) and extends into the interior of the base (1). The outer surface of the stop plate (723) abuts against the outer surface of the ductile plate (71).

8. A pharmaceutical centrifugal filtration device according to claim 7, characterized in that: The other end of the abutment (723) is fixedly connected to a connecting bar (724). The outer surface of the connecting bar (724) is slidably connected to the inside of the inner cavity (722). A spring rod (725) is fixedly connected to the outer surface of the connecting bar (724). One end of the spring rod (725) is fixedly connected to the inside of the inner cavity (722). An air inlet pipe (726) and an exhaust pipe (727) are respectively connected through the two sides inside the inner cavity (722).

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