DNA extraction and amplification integrated machine

CN123027110APending Publication Date: 2026-11-03YANGZHOU UNIV
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Patent Information

Application Number
CN202611548410.9
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2026-10-08
Publication Date
2026-11-03

AI Technical Summary

Technical Problem

Existing microfluidic detection devices cannot simultaneously react, extract, and amplify solutions in multiple microfluidic chips sequentially. The accuracy of amplification detection is insufficient, and it also limits the optimization of microfluidic chip structure integration and detection methods.

Method used

A DNA extraction and amplification integrated machine was designed, including a chip storage component and an amplification and extraction component. The extraction and cleaning of nucleic acids are achieved by using magnets to attract magnetic beads, and the flow of the solution is controlled by push-pull rods and transmission components. The amplification reaction is accelerated by combining a heating component.

Benefits of technology

This technology enables simultaneous reaction, extraction, and amplification of multiple microfluidic chips, improving detection efficiency and accuracy, reducing the risk of external contamination, and enhancing the integration of microfluidic chips and optimizing the detection method.

✦ Generated by Eureka AI based on patent content.

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Abstract

The application discloses a DNA extraction and amplification integrated machine, which comprises a chip storage assembly, a chip storage box is arranged on the chip storage assembly, a plurality of vertically arranged insertion slots for inserting micro-fluidic chips are arranged on the chip storage box, the micro-fluidic chips are provided with extraction cavities, rotating connection amplification pieces are arranged on the micro-fluidic chips below the extraction cavities, and a plurality of amplification pools are arranged in the amplification pieces; the amplification extraction assembly comprises a transmission piece rotatably connected in the chip storage box and a plurality of push-pull rods corresponding to the amplification pieces and capable of making reciprocating linear motion and arranged in the chip storage box, one end of each of the push-pull rods is fixedly connected with a magnet, and the magnet can be attached to the outer wall of the micro-fluidic chip at the extraction cavity; the transmission piece is in transmission connection with the amplification pieces; and the application can sequentially perform reaction, extraction and amplification on multiple micro-fluidic chips at the same time, and is convenient for subsequent detection requirements.
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