Biological protein chip reaction instrument

The delta moving mechanism in the biological protein chip reactor addresses the slow speed and shaking issues of gantry or XYZ box structures by enhancing movement speed and stability, reducing reagent contamination.

CN222212784UActive Publication Date: 2024-12-20XIAMEN OMLITE BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202420593766.4
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-03-26
Publication Date
2024-12-20
Estimated Expiration
2034-03-26

AI Technical Summary

Technical Problem

Existing biological protein chip reactors using gantry or XYZ box structures suffer from slow movement speeds and are prone to shaking, leading to reagent contamination.

Method used

A biological protein chip reactor utilizing a delta moving mechanism with three groups of drive components in a three-axis parallel arm structure, featuring a mobile magnetic actuator and magnetic clamping systems, to enhance movement speed and stability.

Benefits of technology

The delta moving mechanism improves the speed and stability of the reactor, reducing reagent contamination and ensuring precise, efficient operation.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to the technical field of biology, and discloses a biological protein chip reaction instrument which comprises a reaction instrument rack, a delta moving mechanism is arranged on the reaction instrument rack, the delta moving mechanism is connected with a moving execution piece, the rack comprises a base and a top sealing plate, a control device is arranged in the base, and the top sealing plate is connected with the control device. A regulation and control assembly is arranged on the front side face of the base, a working platform is fixed to the center of the top face of the base, three sets of magnetic attraction clamping pieces are fixed to the base with the working platform as the center at intervals of 120 degrees, and the magnetic attraction clamping pieces magnetically attract and clamp a sample application executing mechanism, a CCD chip scanning mechanism and a reagent clamping mechanism. The biological protein chip reaction instrument solves the problems that an existing biological protein chip reaction instrument generally adopts a portal frame structure or an XYZ box body structure to carry out three-dimensional space movement of an execution device, but the portal frame structure or the XYZ box body structure is low in movement speed and easy to shake, so that reagents are polluted.
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Description

Technical Field

[0001] The utility model relates to the field of biotechnology, in particular to a biological protein chip reaction instrument. Background Art

[0002] The bioprotein chip reactor is a high-tech laboratory equipment, mainly used for the analysis and detection of bioprotein chips. It is based on biochip technology and realizes the rapid, accurate and sensitive detection of biological molecules such as proteins through specific biochemical reactions. The working principle of the bioprotein chip reactor is mainly based on the principle of template positioning, which allows specific protein molecules to hybridize with the probes on the chip, and by detecting the presence or absence or strength of the fluorescent signal, it can determine whether the corresponding protein exists in the sample, as well as the concentration of the protein and other information.

[0003] Existing biological protein chip reactors generally use a gantry structure or an XYZ box structure to move the actuator in three dimensions. However, the gantry structure or the XYZ box structure has a slow movement speed and is prone to shaking, resulting in reagent contamination.

[0004] To this end, the utility model provides a biological protein chip reaction instrument. Utility Model Content

[0005] In view of the above-mentioned problems existing in the prior art, the purpose of the present utility model is to solve the problem that the existing biological protein chip reactor generally adopts a gantry structure or an XYZ box structure to perform three-dimensional spatial movement of the execution device. However, the movement speed of the gantry structure or the XYZ box structure is slow and is prone to shaking, resulting in reagent contamination.

[0006] A biological protein chip reactor comprises a reactor frame, a delta moving mechanism is arranged on the reactor frame, the delta moving mechanism is connected with a mobile magnetic actuator, the reactor frame comprises a base and a capping plate, a control device is arranged in the base, a regulating component is arranged on the front side of the base, a working platform is fixed on the center of the top surface of the base, three groups of magnetic clamps are fixed on the base with the working platform as the center and are spaced 120 degrees apart, the magnetic clamps respectively magnetically clamp a sample spotting actuator, a CCD chip scanning mechanism and a reagent clamping mechanism.

[0007] As a further solution of the utility model: the base includes an upper bent base plate, a regulating installation portion is arranged on the front side of the upper bent base plate, a sealing plate is screwed on the left and right sides of the upper bent base plate, the pair of sealing plates are also screwed on a lower sealing base plate, the capping plate is screwed on a triangular-like bending piece, the triangular-like bending piece is provided with a first bending portion at the triangle, the capping plate is a regular triangle, and a bending closing portion is provided on the capping plate at the triangle.

[0008] As a further solution of the utility model: the delta moving mechanism includes three groups of driving components, and the three groups of driving components are fixed on the lower sealing base plate and the top plate at intervals of 120 degrees with the working platform as the center. The driving component includes a driving motor, and the driving motor is fixed inside the base through a motor frame. A first pulley is fixed on the driving shaft of the driving motor, and the first pulley drives the second pulley through a belt, and the second pulley is screwed to the first bending part of the triangular bending part, and the first bending part is also screwed with a contact sensor, and a pair of sliding rods are symmetrically arranged with the belt as the symmetry axis, and a pair of linear bearings are slidably installed on the pair of sliding rods, and the pair of linear bearings are embedded in the sliding part, and the sliding part is connected to a pair of connecting rods, and the other end of the connecting rod is connected to the movable magnetic actuator.

[0009] As a further solution of the utility model: the working platform includes a working platform disc, which is screwed on the upper bending base plate, a working seat is fixed in the center of the working platform disc, the upper end surface of the working seat is a right rounded triangle, the lower part of the working seat is a frustum, a bearing groove is provided at the center of the working seat, a bearing is mounted in the bearing groove, a rotating motor is mounted in the bearing, the rotating motor is screwed on the upper bending base plate through a motor disc, the output shaft of the rotating motor is connected to a separator, a plurality of separation holes are provided on the top surface of the separator, and a separation QR code is provided next to each separation hole.

[0010] As a further solution of the utility model: the work seat extends three groups of connecting rods with the lower circular table of the work seat as the center, and the three groups of connecting rods are all equipped with a first slider, and the three groups of first sliders are respectively fixed with a reaction table, a temporary storage table and a cleaning table, and the reaction table, the temporary storage table and the cleaning table are fixed with a pair of second sliders with the first slider as the symmetry axis, and the bottom of the pair of second sliders is embedded with a pair of slide rails, and the pair of slide rails is fixed on the work platform disc.

[0011] As a further solution of the utility model: the four corners of the reaction table and the temporary storage table are provided with card slots, the outer ring of the card slot is provided with a circular magnetic attraction piece, the reaction table is magnetically attracted with a reaction base through the card slot and the circular magnetic attraction piece, the reaction base is provided with a sink, two spacer bars are provided in the sink, and a groove is provided on each of the two spacer bars, the pair of grooves is used to place a reaction chip, and an ultrasonic cleaner is fixed on the cleaning table.

[0012] As a further solution of the utility model: the temporary storage table is magnetically attracted to a temporary storage rack through a card slot and a circular magnetic attraction member provided on the temporary storage table, and the temporary storage rack is provided with a plurality of temporary storage holes of different sizes, and a temporary storage QR code is provided next to each temporary storage hole.

[0013] As a further solution of the utility model: the upper parts of the sample spotting actuator, CCD chip scanning mechanism and reagent clamping mechanism are all provided with a magnetic table that cooperates with the mobile magnetic actuator, the inner sides of the sample spotting actuator and the reagent clamping mechanism are all provided with a visual observation part, and the outer sides of the sample spotting actuator, CCD chip scanning mechanism and reagent clamping mechanism are provided with a rectangular magnetic part that cooperates with the magnetic clamping part.

[0014] As a further solution of the utility model: the control device includes a core control circuit board and an interface expansion board, the core control circuit board is electrically connected to the interface expansion board, the interface expansion board is electrically connected to the control component, and the control component includes an LED display, a switch button and a control knob.

[0015] As a further solution of the utility model: three horn-shaped anti-slip pads are arranged at the bottom of the lower sealing base plate.

[0016] As described above, the biological protein chip reactor provided by the utility model has the following beneficial effects:

[0017] The utility model utilizes the above-mentioned biological protein chip reactor. Compared with the prior art, due to the use of such a structure, through the setting of a delta moving mechanism, the delta moving mechanism includes three groups of drive components, and the three groups of drive components are operated in a three-axis parallel arm structure, the moving speed is faster, and the influence of the machine movement on the machine itself is smaller, and it is not easy to shake. The problem that the existing biological protein chip reactor generally adopts a gantry structure or an XYZ box structure to move the execution device in three dimensions, but the gantry structure or the XYZ box structure has a slow moving speed and is prone to shaking, resulting in reagent contamination, is solved.

[0018] Additional aspects and advantages of the present invention will be given in part in the following description, and in part will become apparent from the following description, or will be learned through the practice of the present invention. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] In order to more clearly illustrate the embodiments of the utility model or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the utility model. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative labor.

[0020] Figure 1 This is one of the structural schematic diagrams of a biochip spotting instrument applied for in the utility model;

[0021] Figure 2This is a front view of a biochip spotting instrument applied for in the utility model;

[0022] Figure 3 This is the second structural schematic diagram of a biochip spotting instrument applied for in the utility model;

[0023] Figure 4 This is a top view of a biochip spotting instrument applied for in the utility model;

[0024] Figure 5 for Figure 4 Sectional view along AA direction;

[0025] Figure 6 This is a bottom view of a biochip spotting instrument applied for by the utility model;

[0026] Figure 7 for Figure 6 Cross-sectional view along the BB direction;

[0027] Figure 8 The present invention is a schematic diagram of the structure of an operating platform of a biochip spotter applied for in the present invention.

[0028] Summary of reference numerals:

[0029] 1. Reactor frame; 101. Base; 102. Upper bending base plate; 112. Control installation part; 102. Sealing plate; 103. Lower sealing base plate; 104. Capping plate; 114. Bending and closing part; 105. Triangular bending part; 115. First bending part; 2. Delta moving mechanism; 201. Moving magnetic actuator; 202. Driving assembly; 212. Driving motor; 222. First pulley; 232. Belt; 242. Second pulley; 252. Sliding rod; 262. Contact sensor; 272. Linear bearing; 282. Sliding part; 292. Connecting rod; 3. , control device; 301, core control circuit board; 302, interface expansion board; 4, control component; 401, LED display screen; 402, switch button; 403, control knob; 5, working platform; 501, working platform disc; 502, working seat; 503, rotating motor; 504, separator; 505, reaction table; 515, reaction base; 525, reaction chip; 506, temporary storage table; 516, temporary storage rack; 507, cleaning table; 517, ultrasonic cleaner; 6, magnetic clamp; 7, spotting actuator; 8, CCD chip scanning mechanism; 9, reagent clamping mechanism. DETAILED DESCRIPTION

[0030] The following is a description of the implementation of the present invention by means of specific embodiments. People familiar with the art can easily understand other advantages and effects of the present invention from the contents disclosed in this specification.

[0031] It should be noted that the structures, proportions, sizes, etc. illustrated in the drawings of this specification are only used to match the contents disclosed in the specification for people familiar with this technology to understand and read, and are not used to limit the limiting conditions that can be implemented in this utility model, so they have no substantial technical significance. Any modification of the structure, change of the proportional relationship or adjustment of the size, without affecting the effects that can be produced by the utility model and the purposes that can be achieved, should still fall within the scope of the technical content disclosed in this utility model. At the same time, the terms such as "upper", "lower", "left", "right", "middle" and "one" quoted in this specification are only for the convenience of description, and are not used to limit the scope of the implementation of this utility model. The change or adjustment of their relative relationship, without substantial change in the technical content, should also be regarded as the scope of the implementation of this utility model. The specific structure can be described with reference to the drawings of the patent application.

[0032] The utility model provides a biochip sample spotting instrument, please refer to Figures 1 to 8 As shown, it includes a reactor frame 1, and the reactor frame 1 includes a base 101 and a capping plate 104. The base 101 includes an upper bent base plate 102, and a regulating and mounting portion 112 is arranged on the front side of the upper bent base plate 102. A sealing plate 102 is screwed to the left and right sides of the upper bent base plate 102, and the pair of sealing plates 102 are also screwed to a lower sealed base plate 103, and three horn-shaped anti-skid pads are arranged at the bottom of the lower sealed base plate 103. The capping plate 104 is screwed to a triangular bending piece 105, and the triangular bending piece 105 is provided with a first bending portion 115 at the triangle. The capping plate 104 is a regular triangle, and a bending sealing portion 114 is arranged at the triangle on the capping plate 104. The reactor frame 1 is used to fix or seal other components.

[0033] The reactor frame 1 is provided with a delta moving mechanism 2, the delta moving mechanism 2 is connected with a mobile magnetic actuator 201, the delta moving mechanism 2 includes three groups of driving components 202, the three groups of driving components 202 are fixed on the lower sealing base plate 103 and the top plate 104 at intervals of 120 degrees with the working platform 5 as the center, the driving component 202 includes a driving motor 212, the driving motor 212 is fixed inside the base 101 through a motor frame, and a first pulley 222 is fixed on the driving shaft of the driving motor 212, the first pulley The wheel 222 transmits the second pulley 242 through the belt 232. The second pulley 242 is screwed on the first bending part 115 of the triangular bending part 105. The first bending part 115 is also screwed with a contact sensor 262. A pair of sliding rods 252 are symmetrically arranged with the belt 232 as the symmetry axis. A pair of linear bearings 272 are slidably installed on the pair of sliding rods 252. The pair of linear bearings 272 are embedded in the sliding member 282. The sliding member 282 is connected to a pair of connecting rods 292. The other end of the connecting rod 292 is connected to the movable magnetic actuator 201.

[0034] A control device 3 is arranged in the base 101, and the control device 3 includes a core control circuit board 301 and an interface expansion board 302. The core control circuit board 301 is electrically connected to the interface expansion board 302. A control component 4 is arranged on the front side of the base 101. The control mounting portion 112 of the upper bending base plate 102 is installed with the control component 4. The control component 4 includes an LED display screen 401, a switch button 402 and a control knob 403. The interface expansion board 302 is electrically connected to the LED display screen 401, the switch button 402 and the control knob 403. The LED display screen 401, the switch button 402 and the control knob 403 are used for parameter control of a biological protein chip reactor of the utility model.

[0035] A work platform 5 is fixed on the center of the top surface of the base 101, and the work platform 5 includes a work platform disc 501, and the work platform disc 501 is screwed on the upper bent base plate 102. A work seat 502 is fixed in the center of the work platform disc 501. The upper end surface of the work seat 502 is a regular rounded triangle, and the lower part of the work seat 502 is a round table. A bearing groove is provided at the center of the work seat 502, and a bearing is mounted in the bearing groove. A rotating motor 503 is mounted in the bearing, and the rotating motor 503 is driven by The motor disk is screwed onto the upper bent base plate 102, the output shaft of the rotating motor 503 is connected to a separator 504, the top surface of the separator 504 is provided with a plurality of separation holes, each of which is provided with a separation QR code, the separator 504 is used to mix the diluted reagent, the work seat 502 extends three groups of connecting rods with the lower truncated table of the work seat 502 as the center, the three groups of connecting rods are all installed with a first slider, the three groups of first sliders are respectively fixed with a reaction table 505, a temporary storage table 506 and a cleaning table 50 7, the reaction table 505, the temporary storage table 506 and the cleaning table 507 are fixed with a pair of second sliders with the first slider as the symmetry axis, the bottom of the pair of second sliders are embedded with a pair of slide rails, the pair of slide rails are fixed on the working platform disc 501, the four corners of the reaction table 505 and the temporary storage table 506 are provided with slots, the outer ring of the slot is provided with a circular magnetic attraction piece, the reaction table 505 is magnetically attracted with a reaction base 515 through the slot and the circular magnetic attraction piece, the reaction base 515 is provided with a sink, and two spacer strips are provided in the sink, A groove is provided on each of the two spacer strips, and the pair of grooves is used to place a reaction chip 525. An ultrasonic cleaner 517 is fixed on the cleaning table 507, and the ultrasonic cleaner 517 is used to clean the sample after spotting. The temporary storage table 506 is magnetically attracted to a temporary storage rack 516 through a card slot and a circular magnetic attraction member provided on the temporary storage table 506. The temporary storage rack 516 is provided with a plurality of temporary storage holes of different sizes, and a temporary storage QR code is provided next to each temporary storage hole. The temporary storage holes are used to store experimental reagents such as reaction samples, blocking liquid and pure water.

[0036] The base 101 is fixed with three groups of magnetic clamping members 6 at intervals of 120 degrees with the working platform 5 as the center. The magnetic clamping members 6 respectively magnetically clamp the sample spotting actuator 7, the CCD chip scanning mechanism 8 and the reagent clamping mechanism 9. The upper parts of the sample spotting actuator 7, the CCD chip scanning mechanism 8 and the reagent clamping mechanism 9 are all provided with a magnetic table that cooperates with the mobile magnetic actuator 201. The inner sides of the sample spotting actuator 7 and the reagent clamping mechanism 9 are both provided with visual observation parts. The outer sides of the sample spotting actuator 7, the CCD chip scanning mechanism 8 and the reagent clamping mechanism 9 are provided with a rectangular magnetic member that cooperates with the magnetic clamping member 6.

[0037] Embodiment 1:

[0038] When reagent dilution is required, the mobile magnetic actuator 201 is moved to the reagent clamping mechanism 9 magnetically attracted by the magnetic clamping member 6 through the delta moving mechanism 2, and then the mobile magnetic actuator 201 clamps the reagent clamping mechanism 9 and magnetically attracts it to perform the operation. Then the reagent clamping mechanism 9 is moved to the empty reagent tube on the temporary storage rack 516 through the delta moving mechanism 2. At the same time, the visual observation member provided on the reagent clamping mechanism 9 records and marks the temporary storage QR code corresponding to the temporary storage hole of the temporary storage rack 516 of the empty reagent tube. Then, the reagent clamping mechanism 9 clamps the empty reagent tube and moves it to the separation hole on the separator 504 for placement. After moving to the separation hole, the visual observation member provided on the reagent clamping mechanism 9 also needs to record and mark the corresponding separation QR code of the separation hole. After recording and marking the separation QR code, the reagent clamping mechanism 9 is moved to the magnetic clamping member 6 to which the reagent clamping mechanism 9 belongs through the delta moving mechanism 2 and places it back on the magnetic clamping member 6.

[0039] Then, the magnetic clamping member 6 is moved to the sample spotting actuator 7 magnetically attracted by the magnetic clamping member 6 through the delta moving mechanism 2, and then the mobile magnetic actuator 201 clamps the sample spotting actuator 7 and magnetically attracts it to perform the operation. Then, the sample spotting actuator 7 is moved to the PBS reagent on the temporary storage rack 516 through the delta moving mechanism 2. At the same time, the visual observation member provided on the sample spotting actuator 7 records and marks the temporary storage QR code corresponding to the temporary storage hole of the PBS reagent in the temporary storage rack 516. The sample spotting actuator 7 absorbs the PBS reagent. Take a quantitative reagent, then the spotting actuator 7 moves the empty reagent tube to the separation hole where the empty reagent tube is placed through the delta moving mechanism 2 and places the absorbed PBS reagent in the empty reagent tube, the visual observation component set on the spotting actuator 7 records and marks the separation QR code corresponding to the separation hole of the empty reagent tube in the separator 504, after the PBS reagent is placed, the spotting actuator 7 moves to the ultrasonic cleaner 517 on the cleaning table 507 through the delta moving mechanism 2 for cleaning, after cleaning, the spotting actuator 7 moves to the pure water reagent on the temporary storage rack 516 through the delta moving mechanism 2, and at the same time, the visual observation component set on the spotting actuator 7 records and marks the temporary storage QR code corresponding to the temporary storage hole of the pure water reagent in the temporary storage rack 516, then the spotting actuator 7 absorbs a quantitative reagent from the pure water reagent, then the spotting actuator 7 moves to the separation hole where the empty reagent tube with PBS reagent placed is placed through the delta moving mechanism 2 and places the absorbed pure water in the empty reagent tube with PBS reagent placed, at the same time, the visual observation component set on the spotting actuator 7 The observation part records and marks the temporary storage QR code corresponding to the temporary storage hole of the temporary storage rack 516 of the empty reagent tube containing the PBS reagent. After the pure water is added, the sample spotting actuator 7 is moved to the ultrasonic cleaner 517 on the cleaning table 507 through the delta moving mechanism 2 for cleaning. Then, the sample spotting actuator 7 is moved to the magnetic suction clamp 6 to which the sample spotting actuator 7 belongs through the delta moving mechanism 2 and placed back on the magnetic suction clamp 6. Then, the separator 504 is started to rotate and separate to shake the PBS reagent placed in the separator 504.

[0040] Then, the mobile magnetic actuator 201 moves to the reagent clamping mechanism 9 magnetically attracted by the magnetic clamping member 6 through the delta moving mechanism 2, and then the mobile magnetic actuator 201 clamps the reagent clamping mechanism 9 magnetically to perform operation, and then the reagent clamping mechanism 9 moves to the separation hole where the diluted reagent tube is placed through the delta moving mechanism 2 and clamps it out, and at the same time, the visual observation component arranged on the reagent clamping mechanism 9 records and marks the separation QR code corresponding to the separation hole of the separator 504 for the empty reagent tube, and then the reagent clamping mechanism 9 clamps the diluted reagent tube through the delta moving mechanism 2 and places it on the temporary storage hole of the temporary storage rack 516, and then the visual observation component arranged on the reagent clamping mechanism 9 records and marks the temporary storage QR code corresponding to the temporary storage hole of the temporary storage rack 516 for the pure water reagent.

[0041] Embodiment 2:

[0042] When a reagent reaction is required, the magnetic clamping member 6 is moved to the sample spotting actuator 7 magnetically attracted by the magnetic clamping member 6 through the delta moving mechanism 2, and then the mobile magnetic actuator 201 clamps the sample spotting actuator 7 and magnetically attracts it to perform the operation, and then the sample spotting actuator 7 is moved to the sample reagent on the temporary storage rack 516 through the delta moving mechanism 2 to take samples, and at the same time, the visual observation member provided on the sample spotting actuator 7 records and marks the temporary storage QR code corresponding to the temporary storage hole of the sample reagent in the temporary storage rack 516, and then the sample spotting actuator 7 is moved to the reaction chip 525 on the reaction table 505 through the delta moving mechanism 2 for sample spotting, and after the sample spotting is completed, the sample spotting actuator 7 is moved to the ultrasonic cleaner 517 on the cleaning table 507 through the delta moving mechanism 2 for cleaning, and after cleaning, the sample spotting actuator 7 is moved to the magnetic clamping member 6 to which the sample spotting actuator 7 belongs through the delta moving mechanism 2 and placed back on the magnetic clamping member 6;

[0043] After the sample reacts, the magnetic clamping member 6 is moved to the CCD chip scanning mechanism 8 magnetically attracted by the magnetic clamping member 6 through the delta moving mechanism 2, and then the mobile magnetic actuator 201 clamps the CCD chip scanning mechanism 8 and magnetically attracts it to operate, and then the CCD chip scanning mechanism 8 is moved to the reaction chip 525 through the delta moving mechanism 2 for scanning, marking and recording.

[0044] It is obvious to those skilled in the art that the present invention is not limited to the details of the exemplary embodiments described above, and that the present invention can be implemented in other specific forms without departing from the spirit or essential features of the present invention. Therefore, the embodiments should be regarded as exemplary and non-restrictive from any point of view, and the scope of the present invention is defined by the appended claims rather than the above description, and it is intended that all changes falling within the meaning and scope of the equivalent elements of the claims be included in the present invention. Any reference numeral in a claim should not be regarded as limiting the claim to which it relates.

Claims

1. A biological protein chip reactor, It is characterized in that The invention comprises a reaction instrument frame, on which a delta moving mechanism is arranged, and the delta moving mechanism is connected with a moving magnetic actuator, the reaction instrument frame comprises a base and a capping plate, a control device is arranged in the base, a regulating component is arranged on the front side of the base, a working platform is fixed on the center of the top surface of the base, and three groups of magnetic clamps are fixed on the base with the working platform as the center and are spaced 120 degrees apart, and the magnetic clamps respectively magnetically clamp a sample spotting actuator, a CCD chip scanning mechanism and a reagent clamping mechanism.

2. A biological protein chip reactor according to claim 1, It is characterized in that The base includes an upper bent base plate, a regulating installation portion is arranged on the front side of the upper bent base plate, a sealing plate is screwed to the left and right sides of the upper bent base plate, the pair of sealing plates are also screwed to the lower sealing base plate, the capping plate is screwed to a triangular bending piece, the triangular bending piece is provided with a first bending portion at the triangle, the capping plate is a regular triangle, and a bending closing portion is provided at the triangle on the capping plate.

3. A biological protein chip reactor according to claim 2, It is characterized in that The delta moving mechanism includes three groups of driving components, and the three groups of driving components are fixed on the lower sealing base plate and the top plate at intervals of 120 degrees with the working platform as the center. The driving component includes a driving motor, and the driving motor is fixed inside the base through a motor frame. A first pulley is fixed on the driving shaft of the driving motor, and the first pulley drives the second pulley through a belt, and the second pulley is screwed to the first bending part of the triangular bending part, and the first bending part is also screwed with a contact sensor, and a pair of sliding rods are symmetrically arranged with the belt as the symmetry axis, and a pair of linear bearings are slidably installed on the pair of sliding rods, and the pair of linear bearings are embedded in the sliding part, and the sliding part is connected to a pair of connecting rods, and the other end of the connecting rod is connected to the moving magnetic actuator.

4. A biological protein chip reactor according to claim 3, It is characterized in that The working platform includes a working platform disc, which is screwed on the upper bending base plate. A working seat is fixed in the center of the working platform disc. The upper end surface of the working seat is a right rounded triangle. The lower part of the working seat is a frustum. A bearing groove is provided at the center of the working seat. A bearing is mounted in the bearing groove. A rotating motor is mounted in the bearing. The rotating motor is screwed on the upper bending base plate through a motor disc. The output shaft of the rotating motor is connected to a separator. A plurality of separation holes are provided on the top surface of the separator. A separation QR code is provided next to each separation hole.

5. A biological protein chip reaction instrument according to claim 4, It is characterized in that The working seat extends three groups of connecting rods with the lower truncated table of the working seat as the center, and the three groups of connecting rods are all equipped with a first slider, and the three groups of first sliders are respectively fixed with a reaction table, a temporary storage table and a cleaning table, and the reaction table, the temporary storage table and the cleaning table are fixed with a pair of second sliders with the first slider as the symmetry axis, and the bottom of the pair of second sliders is embedded with a pair of slide rails, and the pair of slide rails is fixed on the working platform disc.

6. A biological protein chip reaction instrument according to claim 5, It is characterized in that The four corners of the reaction table and the temporary storage table are provided with card slots, the outer ring of the card slot is provided with a circular magnetic attraction piece, the reaction table is magnetically attracted with a reaction base through the card slot and the circular magnetic attraction piece, the reaction base is provided with a sink, two spacer bars are provided in the sink, and a groove is provided on each of the two spacer bars, the pair of grooves is used to place a reaction chip, and an ultrasonic cleaner is fixed on the cleaning table.

7. A biological protein chip reaction instrument according to claim 6, It is characterized in that The temporary storage table is magnetically attracted to a temporary storage rack through a card slot and a circular magnetic attraction member provided on the temporary storage table. The temporary storage rack is provided with a plurality of temporary storage holes of different sizes, and a temporary storage QR code is provided beside each temporary storage hole.

8. A biological protein chip reaction instrument according to claim 7, It is characterized in that The upper parts of the sample spotting actuator, CCD chip scanning mechanism and reagent clamping mechanism are all provided with a magnetic table that cooperates with the movable magnetic actuator, the inner sides of the sample spotting actuator and the reagent clamping mechanism are all provided with a visual observation part, and the outer sides of the sample spotting actuator, CCD chip scanning mechanism and reagent clamping mechanism are provided with a rectangular magnetic part that cooperates with the magnetic clamping part.

9. A biological protein chip reactor according to claim 8, It is characterized in that The control device includes a core control circuit board and an interface expansion board, the core control circuit board is electrically connected to the interface expansion board, the interface expansion board is electrically connected to the control component, and the control component includes an LED display, a switch button and a control knob.

10. A biological protein chip reactor according to any one of claims 2 to 9, It is characterized in that Three horn-shaped anti-skid pads are arranged at the bottom of the lower sealing base plate.