Detection kit for gene mutation
By designing a compartment isolation sponge block in the gene mutation detection kit and using a lifting handle and a lifting rod, combining the fitting of the fastening block and the upper cover buckle teeth, the sample outflow problem caused by the test tube mouth is solved, and the sample outflow caused by the unblocked test tube mouth is improved. The stability of the test tube and the effectiveness of the sample.
Patent Information
- Application Number
- CN202420779668.X
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-04-16
- Publication Date
- 2024-12-27
- Estimated Expiration
- 2034-04-16
AI Technical Summary
The existing gene mutation detection kits have no barriers to the test tube during the handling process, resulting in sample outflow and mixing, causing sample failure.
A structure including a kit buckle cover, a kit body, a sponge block and a detection reagent tube was designed to isolate the sponge block through a compartment, use a lifting handle and a lifting rod to improve the stability of the test tube, and fix it by snapping. The combination of blocks, upper cover buckles and shaft nails ensures the stability of the kit cover and the body, and avoids accidental contact and damage.
It effectively avoids sample efflux and test tube damage, improves the stability and convenience of use of test tubes, and ensures the effectiveness of the sample.
Smart Images
Figure CN222248318U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to a gene detection kit, in particular to a detection kit for gene mutation, belonging to the technical field of gene mutation detection related to methimazole-induced granulocytopenia and liver damage. Background Art
[0002] At present, the most commonly used ATDs are methimazole and propylthiouracil, which have good clinical therapeutic effects, but inevitably have some adverse reactions, such as drug rash, granulocytopenia, joint pain and liver damage, etc. Among them, the problem of drug-induced liver damage in patients with hyperthyroidism caused by ATD has always attracted much attention.
[0003] Methimazole tablets are called methimazole, which is the first-line treatment for patients with hyperthyroidism. It has a positive effect and is widely used. Cytopenia is one of the common adverse reactions in its treatment. In severe cases, agranulocytosis may occur. The mortality rate of agranulocytosis can reach 2%, so it must be taken seriously.
[0004] A cell detection kit with announcement number CN220430887U includes a box body, a plastic plate fixedly connected between the two sides of the interior of the box body, a through groove is opened on the top of the plastic plate, a fixing component is arranged inside the through groove, and the fixing component includes a threaded tube; a sponge tube and a test tube, the surface of the threaded tube is threadedly connected to the inner wall of the through groove, the sponge tube can be inserted into the interior of the threaded tube, and the test tube can be inserted into the interior of the sponge tube. The utility model has a certain friction force when sliding between the outer wall of the test tube and the inner wall of the sponge tube, thereby ensuring that the box body can ensure that the test tube will not shake inside the sponge tube during the transportation process, and it is also convenient to replace sponge tubes of different sizes to meet the needs of fixing test tubes of different sizes.
[0005] In the above technical solution, the friction force generated by the sponge tube and the outer wall of the test tube ensures that the test tube will not shake inside the sponge tube, and it is also convenient to replace sponge tubes of different sizes. However, there is no obstruction at the mouth of the test tube and no isolation inside the box body. When the box body is lying on its side or tilted during transportation, the sample in the test tube may flow out, resulting in sample mixing and making the sample invalid. For this reason, we provide a detection kit for gene mutation. Utility Model Content
[0006] The utility model provides a detection kit for gene mutation to solve the problem that the opening of the test tube is not blocked, the box body is not isolated, and the sample in the test tube may flow out when the box body is lying on its side or tilted during transportation, thereby causing sample mixing and making the sample invalid.
[0007] The utility model achieves the above-mentioned purpose through the following technical scheme: a detection kit for gene mutation, comprising a kit snap-on cover, a kit body is movably installed below the kit snap-on cover, a lifting slot is opened below the outer wall of the kit body, a lifting rod is installed on the inner wall of the lifting slot, and a lifting handle is fixedly connected to one end of the lifting rod;
[0008] A compartment is provided inside the reagent kit body, a sponge block is installed inside the compartment, a test tube installation slot is provided inside the sponge block, a detection reagent tube 1 is movably installed inside the test tube installation slot, and a detection reagent tube cover is movably installed above the detection reagent tube 1.
[0009] As a further solution of the utility model: a buckling fixing block is fixedly connected to the outer wall surface of the reagent box buckling cover, and a shaft pin is rotatably installed inside the buckling fixing block.
[0010] As a further solution of the utility model: the central outer wall of the shaft nail is equipped with upper cover buckle teeth, and the lower part of the outer wall of the reagent box buckle cover is fixedly connected to a limited stop rod.
[0011] As a further solution of the utility model: a buckle-toothed limiting block is fixedly connected to the outer wall of the reagent box body.
[0012] As a further solution of the utility model: a test tube cover installation groove is provided at the upper end of the test tube installation groove.
[0013] As a further solution of the utility model: the detection reagent tube cover is fixedly connected to the outer periphery of the detection reagent tube 1 with a connecting chain.
[0014] As a further solution of the utility model: a limiting groove 1 is provided on the outer periphery of the test tube cover installation groove.
[0015] The beneficial effects of the utility model are:
[0016] 1. The utility model isolates the sponge block through the compartment opened inside the reagent box body, so that the sponge block can be stably installed inside the reagent box body, and then the detection reagent tube 1 is installed inside the test tube installation groove, which improves the stability after installation and is convenient for use. The detection reagent tube cover is buckled on the upper end of the detection reagent tube 1, which effectively prevents the sample inside the detection reagent tube 1 from flowing out and prevents the sample from failing. The user pushes the lifting handle upward to drive the lifting rod, so that the lifting rod lifts the detection reagent tube 1 installed inside the test tube installation groove, which is convenient for the user to take out the detection reagent tube 1 and convenient for the user to use;
[0017] 2. The utility model achieves engagement with the snap-fit fixing block, the upper cover snap teeth and the axis pin disposed on the outside of the reagent box snap-fit cover, and the snap-fit limit block fixed on the outside of the reagent box body, thereby preventing the snap-fit cover of the reagent box from falling off when the snap-fit cover of the reagent box and the reagent box body collide with each other, improving the stability between the snap-fit cover of the reagent box and the reagent box body, improving the safety of the detection reagent tube 1 in the reagent box body, and preventing the detection reagent tube 1 from being damaged. When the snap-fit cover of the reagent box is installed above the reagent box body, the limit stop rod will hold the lifting handle against the detection reagent tube 1, thereby preventing the detection reagent tube 1 from being moved out due to accidental touch, and preventing the detection reagent tube 1 from being damaged, thereby facilitating use by users. BRIEF DESCRIPTION OF THE DRAWINGS
[0018] Figure 1 It is a schematic diagram of the structure of the utility model;
[0019] Figure 2 It is a schematic diagram of the internal structure of the utility model test kit body;
[0020] Figure 3 This is a schematic diagram of the sponge block and compartment structure of the utility model;
[0021] Figure 4 This is a schematic diagram of the planar structure of the utility model;
[0022] Figure 5 This is a schematic diagram of the structure of a detection reagent tube of the utility model.
[0023] In the figure: 1. Snap-fit cover of reagent box; 2. Reagent box body; 3. Snap-fit fixing block; 4. Limit stopper; 5. Upper cover buckle; 6. Axis pin; 7. Buckle limit block; 8. Lifting slide; 9. Lifting rod; 10. Lifting handle; 11. Sponge block; 12. Test tube cover mounting slot; 13. Test tube mounting slot; 14. Limit slot 1; 15. Detection reagent tube 1; 16. Detection reagent tube cover; 17. Connecting chain; 18. Compartment. DETAILED DESCRIPTION
[0024] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model. Embodiment 1
[0025] like Figures 1 to 5As shown, a detection kit for gene mutation comprises a kit snap-fit cover 1, a kit body 2 is movably installed below the kit snap-fit cover 1, a lifting slot 8 is provided below the outer wall of the kit body 2, a lifting rod 9 is installed on the inner wall of the lifting slot 8, a lifting handle 10 is fixedly connected to one end of the lifting rod 9, a compartment 18 is provided inside the kit body 2, a sponge block 11 is installed inside the compartment 18, the sponge block 11 is isolated by the compartment 18 provided inside the kit body 2, so that the sponge block 11 is stably installed inside the kit body 2, a test tube installation slot 13 is provided inside the sponge block 11, and the test tube A detection reagent tube 15 is movably installed inside the installation groove 13. The detection reagent tube 15 is installed inside the test tube installation groove 13 to improve stability after installation and facilitate use. A detection reagent tube cover 16 is movably installed above the detection reagent tube 15. The detection reagent tube cover 16 is snapped on the upper end of the detection reagent tube 15 to effectively prevent the sample inside the detection reagent tube 15 from flowing out and prevent the sample from failing. The user pushes the lifting handle 10 upward to drive the lifting rod 9, so that the lifting rod 9 lifts the detection reagent tube 15 installed inside the test tube installation groove 13, which is convenient for the user to take out the detection reagent tube 15 and use it conveniently. Embodiment 2
[0026] In addition to all the technical features of the first embodiment, the present embodiment also includes: a buckle fixing block 3 is fixedly connected to the outer wall surface of the reagent box buckle cover 1, a shaft pin 6 is rotatably installed inside the buckle fixing block 3, and a top cover buckle tooth 5 is installed on the central outer wall of the shaft pin 6; a limit stopper rod 4 is fixedly connected to the lower part of the outer wall of the reagent box buckle cover 1, a buckle tooth limit block 7 is fixedly connected to the outer wall of the reagent box body 2, a limit groove 14 is provided on the outer periphery of the test tube cover installation groove 12, a connecting chain 17 is fixedly connected to the outer periphery of the detection reagent tube cover 16 and the detection reagent tube 15, a test tube cover installation groove 12 is provided on the upper end of the test tube installation groove 13, and the test tube cover installation groove 12 is provided through the reagent box buckle cover 1 The buckling fixing block 3 is arranged on the outside; the upper cover buckle teeth 5 and the shaft pin 6 cooperate with each other, and buckle with the buckle teeth limiting block 7 fixed on the outside of the reagent kit body 2, so as to prevent the reagent kit buckle cover 1 from falling off when the reagent kit buckle cover 1 and the reagent kit body 2 collide, improve the stability between the reagent kit buckle cover 1 and the reagent kit body 2, improve the safety of the detection reagent tube 15 in the reagent kit body 2, and avoid the detection reagent tube 15 from being damaged. When the reagent kit buckle cover 1 is buckled, the limiting stop rod 4 will resist the lifting handle 10, so as to avoid the detection reagent tube 15 being moved out due to accidental touch, and avoid the detection reagent tube 15 being damaged, which is convenient for users to use.
[0027] Working principle: The sponge block 11 is isolated by the compartment 18 opened inside the reagent box body 2, so that the sponge block 11 can be stably installed inside the reagent box body 2, and then the detection reagent tube 15 is installed inside the test tube installation groove 13, so as to improve the stability after installation and facilitate use. The detection reagent tube cover 16 is buckled on the upper end of the detection reagent tube 15, so as to effectively prevent the sample inside the detection reagent tube 15 from flowing out and prevent the sample from failing.
[0028] The user pushes the lifting handle 10 upward to drive the lifting rod 9 to slide on the inner wall of the lifting slide groove 8, so that the lifting rod 9 lifts the detection reagent tube 15 installed in the test tube mounting groove 13, which is convenient for the user to take out the detection reagent tube 15 and use it. The test tube cover mounting groove 12 and the detection reagent tube cover 16 are matched with each other, and the detection reagent tube cover 16 and the detection reagent tube 15 are limited on the inner wall of the test tube mounting groove 13, and the limiting groove 14 cooperates with each other through the connecting chain 17 to prevent the detection reagent tube 15 from sliding inside the reagent kit body 2.
[0029] The fastening fixing block 3, the upper cover buckle teeth 5 and the axis pin 6 arranged on the outside of the reagent box buckle cover 1 are engaged with the buckle tooth limiting block 7 fixed on the outside of the reagent box body 2 to prevent the reagent box buckle cover 1 from falling off when the reagent box buckle cover 1 and the reagent box body 2 collide. When the reagent box buckle cover 1 is installed on the top of the reagent box body 2, the limiting blocking rod 4 will resist the lifting handle 10, effectively limiting the lifting handle 10, improving the stability between the reagent box buckle cover 1 and the reagent box body 2, improving the safety of the detection reagent tube 15 in the reagent box body 2, avoiding the detection reagent tube 15 from being damaged, avoiding the detection reagent tube 15 from being moved out due to accidental touching, and avoiding the detection reagent tube 15 from being damaged, so as to facilitate the use of the user.
[0030] It is obvious to those skilled in the art that the present invention is not limited to the details of the exemplary embodiments described above, and that the present invention can be implemented in other specific forms without departing from the spirit or essential features of the present invention. Therefore, the embodiments should be regarded as exemplary and non-restrictive from any point of view, and the scope of the present invention is defined by the appended claims rather than the above description, and it is intended that all changes falling within the meaning and scope of the equivalent elements of the claims be included in the present invention. Any reference numeral in a claim should not be regarded as limiting the claim to which it relates.
[0031] In addition, it should be understood that although the present specification is described according to implementation modes, not every implementation mode contains only one independent technical solution. This description of the specification is only for the sake of clarity. Those skilled in the art should regard the specification as a whole. The technical solutions in each embodiment may also be appropriately combined to form other implementation modes that can be understood by those skilled in the art.
Claims
1. A kit for detecting gene mutations, comprising a kit snap-on cover (1), characterized in that: A reagent box body (2) is movably mounted below the reagent box snap-on cover (1); a lifting slot (8) is provided below the outer wall of the reagent box body (2); a lifting rod (9) is mounted on the inner wall of the lifting slot (8); and a lifting handle (10) is fixedly connected to one end of the lifting rod (9); A compartment (18) is provided inside the reagent kit body (2), a sponge block (11) is installed inside the compartment (18), a test tube installation groove (13) is provided inside the sponge block (11), a detection reagent tube 1 (15) is movably installed inside the test tube installation groove (13), and a detection reagent tube cover (16) is movably installed above the detection reagent tube 1 (15).
2. A detection kit for gene mutation according to claim 1, characterized in that: A buckling fixing block (3) is fixedly connected to the outer wall surface of the reagent kit buckling cover (1), and a shaft pin (6) is rotatably mounted inside the buckling fixing block (3).
3. A detection kit for gene mutation according to claim 2, characterized in that: The central outer wall of the shaft pin (6) is provided with an upper cover buckle tooth (5), and the lower part of the outer wall of the reagent box buckle cover (1) is fixedly connected with a limit stop rod (4).
4. A detection kit for gene mutation according to claim 1, characterized in that: A buckled limiting block (7) is fixedly connected to the outer wall of the reagent kit body (2).
5. A detection kit for gene mutation according to claim 1, characterized in that: A test tube cover mounting groove (12) is provided at the upper end of the test tube mounting groove (13).
6. A detection kit for gene mutation according to claim 1, characterized in that: The detection reagent tube cover (16) is fixedly connected to the outer periphery of the detection reagent tube 1 (15) via a connecting chain (17).
7. A detection kit for gene mutation according to claim 5, characterized in that: A limiting groove (14) is provided on the outer periphery of the test tube cover installation groove (12).