Multifunctional layered macrophage culture plate
By adopting a combination design of pull-out plate and shell structure in the macrophage culture plate, the problem of poor stability of the plate cover is solved, the sealing of the culture plate is improved, impurities are prevented from entering, and the stability of cell culture is ensured .
Patent Information
- Application Number
- CN202323639804.X
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2023-12-29
- Publication Date
- 2024-12-27
- Estimated Expiration
- 2033-12-29
AI Technical Summary
The board cover clamping stability of existing macrophage culture plates is poor, which can easily lead to separation of the culture plate from the board cover, and impurities such as dust enter the culture plate, affecting cell culture.
A multifunctional layered macrophage culture plate is designed, adopting a pull-out plate and shell structure, through supporting blocks, jacks, hard springs, fixed blocks, sliders, chutes, return springs and movable rods and other components. , achieving stable fixation and enclosure of the culture plate.
It effectively prevents the separation of the culture plate from the cover, reduces the entry of impurities such as dust, thereby improving the sealing and stability of the culture environment.
Smart Images

Figure CN222250770U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of macrophages, in particular to a multifunctional layered macrophage culture plate. Background Art
[0002] Macrophages are a type of white blood cell located in tissues. They originate from monocytes, which in turn originate from precursor cells in the bone marrow. Both macrophages and monocytes are phagocytes, and participate in nonspecific defense (innate immunity) and specific defense (cellular immunity) in vertebrates. Their main function is to phagocytose (i.e., engulf and digest) cell fragments and pathogens in the form of fixed cells or free cells, and activate lymphocytes or other immune cells to respond to pathogens. Macrophages are immune cells with multiple functions and are an important subject for studying cellular phagocytosis, cellular immunity, and molecular immunology. Macrophages are easy to obtain, easy to culture, and can be purified. Macrophages are a non-reproductive cell group that can live for 2-3 weeks under suitable conditions. They are mostly used for primary culture and are difficult to survive for a long time.
[0003] In the process of macrophage culture, culture plates are needed. Although the existing culture plates have good transparency and are non-toxic and sterile, the stability of the plate covers when they are buckled may be poor, which can easily cause the culture plate and the plate cover to separate. The sealing is poor, and impurities such as dust can easily fall into the culture plate, thereby affecting the internal cells.
[0004] Therefore, those skilled in the art provide a multifunctional layered macrophage culture plate to solve the problems raised in the above background technology. Utility Model Content
[0005] The technical problem to be solved by the utility model is that in the prior art, the stability of the culture plate cover when it is buckled may be poor, which can easily cause the culture plate and the plate cover to separate, and dust and the like can easily fall into the culture plate. For this reason, we propose a multifunctional layered macrophage culture plate.
[0006] In order to achieve the above purpose, the utility model provides the following technical solutions:
[0007] A multifunctional layered macrophage culture plate comprises a pull-out plate and a shell, wherein a support block is fixedly connected to the top of the pull-out plate, a plug hole is provided on the top of the support block, and an assembly mechanism is provided on the top of the shell, wherein the assembly mechanism comprises a box body;
[0008] The box body is fixedly installed on the top of the shell, the top of the inner cavity of the box body is fixedly connected with a hard spring, the bottom of the hard spring is fixedly connected with a fixed block, the inner side of the fixed block is fixedly connected with an insertion rod, and the inner side of the insertion rod is inserted into the inner cavity of the jack.
[0009] As a further solution of the utility model: both left and right sides of the pull-out plate are fixedly connected with a holder, and the inner side of the holder is clamped with the culture plate body.
[0010] As a further solution of the utility model: the left and right sides of the fixed block are fixedly connected with sliders, the left and right sides of the inner cavity of the box body are provided with sliding grooves, and the outer sides of the sliders are slidably connected to the inner cavity of the sliding grooves.
[0011] As a further solution of the utility model: a plurality of placement grooves are provided on the top of the culture plate body, installation grooves are provided on both the left and right sides of the inner cavity of the placement grooves, and a reset spring is fixedly connected to the inner side of the inner cavity of the installation grooves.
[0012] As a further solution of the utility model: a movable rod is fixedly connected to the outer side of the return spring, and a clamping plate is fixedly connected to the outer side of the movable rod.
[0013] As a further solution of the utility model: a draw groove is opened on the front side of the box body, a pull rod is fixed on the front side of the fixing block, and the pull rod passes through the inner cavity of the draw groove and extends to the outside of the box body.
[0014] As a further solution of the utility model: a rectangular groove is opened at the middle end of the top of the inner cavity of the shell, and the support block is slidably connected to the inner cavity of the rectangular groove, and a handle is fixedly connected to the front side of the pull-out plate.
[0015] The beneficial effects of the utility model are:
[0016] 1. The utility model can facilitate the fixation of the culture plate body through the clamping seat. The pull rod is pulled upward to drive the fixing block to move upward, and the fixing block drives the insertion rod to move upward. Through the cooperation of the support block and the rectangular groove, the culture plate body enters the inner cavity of the shell. Then, the pull rod is released, and the fixing block drives the insertion rod to move downward and plug into the inner cavity of the jack to complete the assembly, so that the culture plate body is not easy to separate from the shell, and the occurrence of impurities such as dust easily falling into the culture plate due to poor sealing is reduced.
[0017] 2. The utility model can conveniently fix the culture plate body by arranging a holder, can improve the stability of the fixed block during movement by arranging a slider and a slide groove, can conveniently fix the reset spring by arranging an installation groove, and can play a role of fixed installation by arranging a movable rod and a clamping plate, and can squeeze the reset spring through the movable rod so that the clamping plate can fix the culture dish in the placement groove. BRIEF DESCRIPTION OF THE DRAWINGS
[0018] Figure 1 A schematic diagram of the structure of a multifunctional layered macrophage culture plate;
[0019] Figure 2 A schematic diagram of the structure of a pull-out plate and a shell assembly state in a multifunctional layered macrophage culture plate;
[0020] Figure 3 A schematic diagram of the assembly mechanism structure in a multifunctional layered macrophage culture plate;
[0021] Figure 4 This is a schematic diagram of the cross-sectional structure of the mounting groove in a multifunctional layered macrophage culture plate.
[0022] In the figure: 1. pull-out plate; 2. assembly mechanism; 201. box body; 202. hard spring; 203. fixing block; 204. plug rod; 205. holder; 206. culture plate body; 207. slider; 208. slide groove; 209. placement groove; 210. installation groove; 211. reset spring; 212. movable rod; 213. splint; 214. pull groove; 215. pull rod; 3. shell; 4. support block; 5. socket; 6. rectangular groove; 7. handle. DETAILED DESCRIPTION
[0023] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.
[0024] See also Figure 1-4 A multifunctional layered macrophage culture plate comprises a pull-out plate 1 and a shell 3, a support block 4 is fixedly connected to the top of the pull-out plate 1, a plug hole 5 is provided on the top of the support block 4, an assembly mechanism 2 is provided on the top of the shell 3, and the assembly mechanism 2 comprises a box 201;
[0025] The box body 201 is fixedly installed on the top of the shell 3, the top of the inner cavity of the box body 201 is fixedly connected with a hard spring 202, the bottom of the hard spring 202 is fixedly connected with a fixed block 203, the inner side of the fixed block 203 is fixedly connected with an insertion rod 204, and the inner side of the insertion rod 204 is inserted into the inner cavity of the socket 5.
[0026] Through the above technical scheme, the culture plate body 206 can be conveniently fixed through the socket 205, and the pull rod 215 is pulled upward to drive the fixing block 203 to move upward, and the fixing block 203 drives the insertion rod 204 to move upward, and the culture plate body 206 enters the inner cavity of the shell 3 through the cooperation of the support block 4 and the rectangular groove 6. Then, the pull rod 215 is released, and the fixing block 203 drives the insertion rod 204 to move downward and be plugged into the inner cavity of the socket 5 to complete the assembly, so that the culture plate body 206 is not easily separated from the shell 3, and the occurrence of dust and other impurities easily falling into the culture plate due to poor sealing is reduced.
[0027] Specifically, the left and right sides of the pull-out plate 1 are fixedly connected with a holder 205 , and the inner side of the holder 205 is clamped with the culture plate body 206 .
[0028] Through the above technical solution, by setting the holder 205, the culture plate body 206 can be conveniently fixed.
[0029] Specifically, the left and right sides of the fixed block 203 are fixedly connected with sliders 207 , the left and right sides of the inner cavity of the box body 201 are provided with slide grooves 208 , and the outer sides of the sliders 207 are slidably connected in the inner cavity of the slide grooves 208 .
[0030] Through the above technical solution, by providing the slider 207 and the slide groove 208, the stability of the fixed block 203 during the movement can be improved.
[0031] Specifically, a plurality of placement grooves 209 are provided on the top of the culture plate body 206 , and installation grooves 210 are provided on both the left and right sides of the inner cavity of the placement grooves 209 , and a return spring 211 is fixedly connected to the inner side of the inner cavity of the installation grooves 210 .
[0032] Through the above technical solution, by providing the installation groove 210, the return spring 211 can be conveniently fixed to achieve a fixed installation effect.
[0033] Specifically, the outer side of the return spring 211 is fixedly connected with the movable rod 212 , and the outer side of the movable rod 212 is fixedly connected with the clamping plate 213 .
[0034] According to the above technical solution, by providing the movable rod 212 and the clamping plate 213 , the movable rod 212 can squeeze the reset spring 211 , so that the clamping plate 213 can fix the culture dish in the placement groove 209 .
[0035] Specifically, a groove 214 is formed on the front side of the box body 201 , a pull rod 215 is fixed on the front side of the fixing block 203 , and the pull rod 215 passes through the inner cavity of the groove 214 and extends to the outside of the box body 201 .
[0036] Through the above technical solution, by providing the pull groove 214, the pull rod 215 can be limited to prevent the pull rod 215 from deviating during the movement.
[0037] Specifically, a rectangular groove 6 is provided at the middle end of the top of the inner cavity of the shell 3 , and the support block 4 is slidably connected in the inner cavity of the rectangular groove 6 , and a handle 7 is fixedly connected to the front side of the pull-out plate 1 .
[0038] Through the above technical solution, by providing the rectangular groove 6, the support block 4 and the shell 3 can be connected to facilitate initial fixation.
[0039] The working principle of the utility model is as follows: a multifunctional layered macrophage culture plate, firstly, a culture dish is placed inside the placement groove 209, and the clamping plate 213 presses the movable rod 212 inwardly, so that the movable rod 212 moves inwardly to press the reset spring 211 to produce deformation, so that the clamping plate 213 fixes the culture dish, and the culture plate body 206 can be fixed in the inner cavity of the pull-out plate 1 through the clamping seat 205;
[0040] Then, the pull rod 215 is pulled upward to drive the fixed block 203 to move upward, and the fixed block 203 drives the insertion rod 204 to move upward. At the same time, the fixed block 203 squeezes the hard spring 202 to deform, and then the pull-out plate 1 is slid to the inner cavity of the rectangular groove 6 through the support block 4, so that the culture plate body 206 enters the inner cavity of the shell 3. At this time, the pull rod 215 is released, and the hard spring 202 is deformed due to the influence of the loss of force and drives the fixed block 203 to move downward, and the fixed block 203 drives the insertion rod 204 to move downward and plug into the inner cavity of the jack 5 to complete the assembly, so that the culture plate body 206 is not easy to separate from the shell 3, reducing the occurrence of impurities such as dust easily falling into the culture plate due to poor sealing;
[0041] When it is necessary to check the culture dish in the culture plate body 206, the pull rod 215 is pulled upward to drive the fixed block 203 to move upward, and the fixed block 203 drives the insertion rod 204 to move upward and make the insertion rod 204 leave the inner cavity of the socket 5, thereby releasing the limit on the culture plate body 206. Subsequently, the pull-out plate 1 is pulled outward by the handle 7 to drive the support block 4 to leave the inner cavity of the rectangular groove 6, so that the culture plate body 206 is separated from the shell 3, thereby facilitating the viewing of the culture process.
[0042] What is described above is only a preferred specific implementation manner of the present invention, but the protection scope of the present invention is not limited thereto. Any technician familiar with the technical field can make equivalent replacements or changes within the technical scope disclosed by the present invention according to the technical scheme and the utility model concept of the present invention, which should be covered by the protection scope of the present invention.
Claims
1. A multifunctional layered macrophage culture plate, comprising a pull-out plate (1) and a shell (3), characterized in that: The top of the pull-out plate (1) is fixedly connected to a support block (4), the top of the support block (4) is provided with a plug hole (5), the top of the shell (3) is provided with an assembly mechanism (2), and the assembly mechanism (2) comprises a box body (201); The box body (201) is fixedly installed on the top of the shell (3); the top of the inner cavity of the box body (201) is fixedly connected to a hard spring (202); the bottom of the hard spring (202) is fixedly connected to a fixed block (203); the inner side of the fixed block (203) is fixedly connected to an insertion rod (204); the inner side of the insertion rod (204) is inserted into the inner cavity of the jack (5).
2. The multifunctional stratified macrophage culture plate according to claim 1, characterized in that: The left and right sides of the pull-out plate (1) are both fixedly connected with a holder (205), and the inner side of the holder (205) is clamped with a culture plate body (206).
3. The multifunctional stratified macrophage culture plate according to claim 1, characterized in that: The left and right sides of the fixed block (203) are fixedly connected with sliding blocks (207), the left and right sides of the inner cavity of the box body (201) are provided with sliding grooves (208), and the outer sides of the sliding blocks (207) are slidably connected in the inner cavity of the sliding grooves (208).
4. The multifunctional layered macrophage culture plate according to claim 2, characterized in that: The top of the culture plate body (206) is provided with a plurality of placement grooves (209), and installation grooves (210) are provided on both the left and right sides of the inner cavity of the placement grooves (209), and a return spring (211) is fixedly connected to the inner side of the inner cavity of the installation grooves (210).
5. The multifunctional layered macrophage culture plate according to claim 4, characterized in that: The outer side of the return spring (211) is fixedly connected to a movable rod (212), and the outer side of the movable rod (212) is fixedly connected to a clamping plate (213).
6. The multifunctional stratified macrophage culture plate according to claim 1, characterized in that: A draw groove (214) is provided on the front side of the box body (201), a pull rod (215) is fixed on the front side of the fixing block (203), and the pull rod (215) passes through the inner cavity of the draw groove (214) and extends to the outside of the box body (201).
7. The multifunctional stratified macrophage culture plate according to claim 1, characterized in that: A rectangular groove (6) is provided at the middle end of the top of the inner cavity of the shell (3), and the support block (4) is slidably connected in the inner cavity of the rectangular groove (6), and a handle (7) is fixedly connected to the front side of the pull-out plate (1).
