Bulk drug filling production device

Abstract

The utility model relates to the technical field of liquid filling, and provides a raw material medicine filling production device which solves the problems that existing raw material medicine filling equipment cannot achieve high-precision filling according to the preset filling amount, and bubbles are prone to being generated during raw material medicine filling. Comprising a filling table and a bottle body, a U-shaped groove for fixing the bottle body is formed in the filling table, a mounting base is fixedly mounted on the filling table, a liquid storage tank is fixedly mounted on the mounting base, a top cover is mounted at the top of the liquid storage tank, the top cover is a piston with a hole, and an air guide pipe and a liquid guide pipe are connected to the top cover; the air guide pipe is connected with a flow pump, the liquid guide pipe is connected with an air pressure sensor, the air pressure sensor is communicated with a filling needle head with a drip-proof valve through a guide pipe, a weight sensor is arranged in the U-shaped groove, and a control screen is further fixedly installed on the filling table. And the control screen is electrically connected with the air pressure sensor and the weight sensor.

Description

Technical Field

[0001] The utility model relates to the technical field of liquid filling, in particular to a raw material medicine filling production device. Background Art

[0002] With the rapid development of the pharmaceutical industry, drug filling technology is also accelerating. The production department of chemical drugs consists of two parts: API production and drug preparation production. API is the material basis of drug production, but it must be processed into drug preparations suitable for taking before it can become a drug. In the pharmaceutical process, the ointment needs to be divided into small medicine bottles, which is drug filling. In drug filling, pharmaceutical filling equipment is usually used for filling, which can greatly improve production efficiency. Traditional API filling equipment has problems such as slow filling speed, low precision, and easy pollution, which cannot meet the needs of the modern pharmaceutical industry. Therefore, it is necessary to develop a new API filling production device to improve production efficiency and product quality.

[0003] Chinese patent application No. 202222214089.4 discloses a filling device for the production of pharmaceutical raw materials, including a support column, a medicine tank fixedly installed on one side of the support column, a hopper arranged on the top of the medicine tank, a support plate fixedly installed on one side of the support column, a sliding tube fixedly installed on the top of the support plate, a sliding seat slidably connected inside the sliding tube, a loading plate fixedly connected on the top of the sliding seat, a non-slip pad fixedly connected on the top of the loading plate, a first triggering piece fixedly installed on the bottom of the sliding seat, a second triggering piece fixedly installed inside the sliding tube, and a spring fixedly connected inside the sliding tube and the bottom of the sliding seat. After the medicine bottle of the utility model is filled with medicine, the first triggering piece will contact the second triggering piece, the medicine pump stops filling, and the accuracy of medicine filling is improved. The stirring motor drives the rotating rod and the stirring rod to rotate, and the stirring rod stirs the medicine inside the medicine tank to prevent the raw materials from settling, which affects the medicine pump from extracting medicine and improves the stability of the medicine pump when extracting. However, the device cannot achieve high-precision filling according to the preset filling volume, and the spring may age and deform over a long period of use, resulting in inaccurate filling volume.

[0004] Chinese patent application No. 202321567950.3 discloses an automatic feeding and discharging device for raw materials, including a main body component, the main body component includes a box, the left and right side walls inside the box are horizontally provided with triangular plates, the front and rear side walls inside the box are horizontally provided with support blocks, the support blocks are located below the triangular plates, the number of support blocks is four, a feed pipe is provided at the top of the box, a support is fixedly connected to the bottom of the box, a discharging component is provided inside the box, and the discharging component includes a horizontal plate, the right end of the horizontal plate horizontally penetrates the left side wall of the box and extends to the inside. The utility model can automatically discharge materials through the discharging component provided, avoiding direct contact between the staff and the raw materials and causing contamination of the raw materials and harmful stimulation to the skin, and the stirring and cleaning components provided can fully stir the raw materials, thereby improving production efficiency; the environment in the box is kept clean by automatic cleaning, which is convenient for subsequent use. However, the device cannot automatically stop filling according to the preset filling volume, and there is a problem of low filling accuracy. Utility Model Content

[0005] Therefore, in view of the above problems, the utility model provides a raw material drug filling production device to solve the problem that the existing raw material drug filling equipment cannot achieve high-precision filling according to the preset filling volume, and bubbles are easily generated during the filling of the raw material drug.

[0006] In order to achieve the above purpose, the utility model adopts the following technical solutions:

[0007] A raw material medicine filling production device comprises a filling table and a bottle body, wherein the filling table is provided with a U-shaped groove for fixing the bottle body, the filling table is fixedly provided with a mounting base, a liquid storage tank is fixedly provided on the mounting base, a top cover is provided on the top of the liquid storage tank, the top cover is a piston with holes, and an air guide tube and a liquid guide tube are connected to the top cover, the air guide tube is connected to a flow pump, the liquid guide tube is connected to an air pressure sensor, the air pressure sensor is connected to a filling needle with an anti-drip valve through a conduit, a weight sensor is provided inside the U-shaped groove, a control screen is also fixedly provided on the filling table, and the control screen is electrically connected to the air pressure sensor and the weight sensor.

[0008] Furthermore, the anti-drip valve adopts a pneumatic shut-off valve, and a pneumatic control device is used to convert compressed air into mechanical energy to drive the movement of the valve core, thereby controlling the opening of the anti-drip valve.

[0009] Furthermore, the air guide tube is above the liquid level of the liquid storage tank, and the liquid guide tube is below the liquid level of the liquid storage tank.

[0010] Furthermore, a bubble filter cavity is provided inside the catheter, and a hydrophilic porous membrane is provided inside the bubble filter cavity.

[0011] Furthermore, a plurality of microholes are provided on the side wall of the filling needle, and the lower ends of the microholes are recessed into the wall, and the recessed angle is 15-45 degrees.

[0012] Furthermore, the upper end of the top cover is fixedly connected to a stirring motor, and the output end of the stirring motor is fixedly connected to a stirring paddle.

[0013] By adopting the above technical solution, the beneficial effects of the utility model are:

[0014] 1. Input the preset flow value of the API on the control panel. The control panel sends the data to the air pressure sensor and calculates the relevant parameters and sends them to the flow pump. The output voltage drives the flow pump to output gas through the air pipe connected to the liquid storage tank. The gas pressure causes the liquid pipe below the liquid level of the liquid storage tank to press out the API. The high-precision weight sensor installed inside the U-shaped groove monitors the weight data of the API in real time and feeds back to the control panel.

[0015] 2. Before the API with bubbles is filled into the bottle, it passes through the bubble filter cavity, where the API infiltrates the hydrophilic porous membrane. At this time, pressure is applied to the bubble filter cavity, and the liquid API passes through the hydrophilic porous membrane under the pressure difference between the cavity and the outside, thereby eliminating the bubbles. Then the liquid API passes through the filling needle, and a plurality of micropores are arranged on the side wall of the filling needle. The lower end of the micropores is recessed into the wall, and the recessed angle is 15-45 degrees, so that the liquid column of the liquid API is in an inclined state when entering the bottle, and the liquid column slowly flows into the bottle along the wall, which can avoid the collision between liquids due to the gravity of the liquid when the liquid column is added vertically to generate more bubbles.

[0016] 3. A filling needle with an anti-drip valve is provided. When the anti-drip valve is installed, the water outlet of the valve no longer bears the pressure of the water inlet. During filling, the gap is sealed by the tension of the liquid API; when filling is stopped, the gap is sealed by the pressure of the air and no dripping occurs.

[0017] 4. A stirring device is installed in the material tank to prevent the liquid from settling. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 It is a schematic diagram of a raw material medicine filling production device in an embodiment of the utility model;

[0019] Figure 2 This is a schematic diagram of the structure of the anti-drip valve in the embodiment of the utility model;

[0020] Figure 3 This is a schematic diagram of the structure inside the catheter in the embodiment of the utility model;

[0021] Figure 4 This is a schematic diagram of the structure of the filling needle in the embodiment of the utility model;

[0022] Explanation of the numbers in the figure: 1-filling table, 2-bottle body, 3-U-shaped groove, 4-mounting base, 5-liquid storage tank, 6-top cover, 7-air guide tube, 8-liquid guide tube, 9-flow pump, 10-air pressure sensor, 11-catheter, 12-with anti-drip valve, 13-filling needle, 14-weight sensor, 15-control screen, 16-stirring motor, 17-stirring paddle, 18-bubble filter chamber, 19-hydrophilic porous membrane, 20-micropore, 21-lower end of micropore, α-angle of depression. DETAILED DESCRIPTION

[0023] The utility model embodiment is:

[0024] refer to Figure 1 A raw material medicine filling production device comprises a filling table 1 and a bottle body 2, wherein the filling table is provided with a U-shaped groove 3 for fixing the bottle body, the filling table 1 is fixedly installed with a mounting base 4, a liquid storage tank 5 is fixedly installed on the mounting base 4, a top cover 6 is installed on the top of the liquid storage tank 5, a stirring motor 16 is fixedly connected to the upper end of the top cover 5, a stirring paddle 17 is fixedly connected to the output end of the stirring motor, the top cover 6 is a piston with a hole, and an air guide tube 7 and a liquid guide tube 8 are connected to the top cover 6, The air guide tube 7 is above the liquid level of the liquid storage tank, and the liquid guide tube is below the liquid level of the liquid storage tank. The air guide tube 7 is connected to the flow pump 9, and the liquid guide tube 8 is connected to the air pressure sensor 10. The model of the air pressure sensor is MP3V5004G. The air pressure sensor 10 is connected to the filling needle 13 with an anti-drip valve 12 through a conduit 11. A weight sensor 14 is arranged inside the U-shaped groove 3. The model of the weight sensor 14 is a high-precision weight load sensor FH02 ， A control panel 15 is also fixedly mounted on the filling station 1 . The model of the control panel 15 is QS-14H-16X-7.0-B. The control panel 15 is electrically connected to the air pressure sensor 10 and the weight sensor 14 .

[0025] Specifically, refer to Figure 2 The anti-drip valve 12 adopts a pneumatic shut-off valve, the model of which is SKF-Q611F-16P. A pneumatic control device is used to convert compressed air into mechanical energy to drive the movement of the valve core, thereby controlling the opening of the anti-drip valve.

[0026] Specifically, refer to Figure 3 A bubble filter chamber 18 is disposed inside the conduit 11 , and a hydrophilic porous membrane 19 is disposed inside the bubble filter chamber 18 .

[0027] Specifically, refer to Figure 2 and Figure 4A plurality of micro-holes 20 are arranged on the side wall of the filling needle 13, and the lower ends 21 of the micro-holes are recessed into the wall, and the recessed angle α is 30 degrees.

[0028] Although the present invention has been specifically demonstrated and described in conjunction with the preferred embodiments, those skilled in the art should understand that various changes may be made to the present invention in form and detail without departing from the spirit and scope of the present invention as defined in the appended claims, all of which are within the scope of protection of the present invention.

Claims

1. A bulk drug filling production device, comprising a filling station and a bottle body, characterized in that: The filling table is provided with a U-shaped groove for fixing the bottle body, a mounting base is fixedly installed on the filling table, a liquid storage tank is fixedly installed on the mounting base, a top cover is installed on the top of the liquid storage tank, the top cover is a piston with holes, and an air guide tube and a liquid guide tube are connected to the top cover, the air guide tube is connected to a flow pump, the liquid guide tube is connected to an air pressure sensor, the air pressure sensor is connected to a filling needle with an anti-drip valve through a conduit, a weight sensor is arranged inside the U-shaped groove, a control screen is also fixedly installed on the filling table, and the control screen is electrically connected to the air pressure sensor and the weight sensor.

2. A bulk drug filling production device according to claim 1, characterized in that: The anti-drip valve is a pneumatic shut-off valve.

3. The bulk drug filling production device according to claim 1, characterized in that: The air guide tube is above the liquid level of the liquid storage tank, and the liquid guide tube is below the liquid level of the liquid storage tank.

4. The bulk drug filling production device according to claim 1, characterized in that: A bubble filter cavity is arranged inside the catheter, and a hydrophilic porous membrane is arranged inside the bubble filter cavity.

5. The bulk drug filling production device according to claim 1, characterized in that: A plurality of microholes are arranged on the side wall of the filling needle, and the lower ends of the microholes are sunken into the wall, and the angle of the sunken holes is 15-45 degrees.

6. The bulk drug filling production device according to claim 1, characterized in that: The upper end of the top cover is fixedly connected with a stirring motor, and the output end of the stirring motor is fixedly connected with a stirring paddle.

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