Initial position positioning device for micro-fluidic chip

Abstract

The utility model discloses an initial position positioning device for a micro-fluidic chip, which comprises a micro-fluidic chip with a rotation axis; the magnetic component is fixedly arranged on the micro-fluidic chip; the Hall sensor is mounted near the periphery of the micro-fluidic chip so as to detect the magnetic part; the driving motor is configured to be capable of driving the micro-fluidic chip and the magnetic component to synchronously rotate around the rotating axis; and the device is configured to stop the driving motor when the Hall sensor detects the magnetic component, so that the micro-fluidic chip is placed at an initial position.

Description

Technical Field

[0001] The utility model relates to the technical field of microfluidics, in particular to an initial position positioning device for a microfluidics chip. Background Art

[0002] Microfluidic chips can integrate a series of basic operating units involved in the fields of chemistry and biology, such as sample preparation, reaction, separation, and detection, into a small chip. At the same time, the network formed by the microchannels can run through the entire system, with the advantages of precision, high efficiency, miniaturization of instruments, low reagent consumption, and small sample usage.

[0003] Microfluidic chips are usually designed with multiple flow channels to distribute samples to be tested into multiple reaction chambers so that multiple items can be tested on the same sample. Accurately determining the position of each reaction chamber is the basis for realizing automated testing of each reaction chamber.

[0004] At present, the commonly used method is to first accurately determine the initial position of the microfluidic chip, and then use the initial position as a reference to position each reaction chamber in turn. For example, when multiple reaction chambers are evenly spaced around the rotation axis, the drive motor is controlled to operate in a rotation mode with a fixed angle each time, so that each reaction chamber passes through a detection device for detecting the reaction situation in turn.

[0005] The prior art uses two methods: slot-type photoelectric sensors or encoders. The encoder method has the problem of high cost. The slot-type photoelectric sensor method requires the microfluidic chip to be sandwiched between the slot-type photoelectric sensor, which adds more space restrictions and requires through holes on the microfluidic chip. In addition, the reaction chambers on the microfluidic chip are distributed at the edge and are transparent, which will interfere with the photoelectric sensor.

[0006] The information disclosed in this background technology section is only intended to increase the understanding of the overall background of the utility model, and should not be regarded as acknowledging or suggesting in any form that the information constitutes the prior art already known to ordinary technicians in this field. Utility Model Content

[0007] Purpose of the utility model: The technical problem to be solved by the utility model is to provide an initial position positioning device for a microfluidic chip in response to the deficiencies of the prior art, which can position the microfluidic chip to the initial position as a reference, facilitate the positioning of the subsequent reaction chamber, and has lower cost and higher accuracy.

[0008] In order to solve the above technical problems, the utility model discloses an initial position positioning device for a microfluidic chip, the device comprising:

[0009] A microfluidic chip having a rotation axis;

[0010] A magnetic component, fixedly arranged on the microfluidic chip;

[0011] A Hall sensor is installed near the periphery of the microfluidic chip to detect the magnetic component;

[0012] and a driving motor, wherein the driving motor is configured to drive the microfluidic chip and the magnetic component to rotate synchronously around the rotation axis;

[0013] The device is configured to stop the driving motor when the Hall sensor detects the magnetic component to place the microfluidic chip in an initial position.

[0014] Preferably, the magnetic component is located at the peripheral edge of the microfluidic chip.

[0015] Specifically, the microfluidic chip includes a groove for carrying the magnetic component.

[0016] Specifically, the groove is arranged on the upper surface at the peripheral edge of the microfluidic chip.

[0017] Specifically, there is a gap between the Hall sensor and the magnetic component.

[0018] Specifically, the Hall sensor is located on a path along which the magnetic component rotates around the rotation axis.

[0019] Specifically, it comprises a chip fixing shaft, the bottom end of which is drivingly connected to the driving motor, and the top of which is detachably connected to the microfluidic chip.

[0020] Specifically, the microfluidic chip is a disk chip or a fan-shaped chip.

[0021] Specifically, the magnetic component is a magnet.

[0022] Specifically, the microfluidic chip includes more than one reaction chamber, and the more than one reaction chamber is evenly spaced and distributed around the rotation axis.

[0023] Beneficial effects:

[0024] 1) The initial position positioning device for a microfluidic chip provided by the utility model can position the microfluidic chip to the initial position. Taking the initial position as a reference, the positioning of the subsequent reaction chamber can be facilitated.

[0025] 2) The utility model uses magnetic components and Hall sensors as switches to control the stop of the drive motor, thereby positioning the microfluidic chip to the initial position. Compared with the traditional method of using encoders, the device cost of the utility model is lower. Compared with the method of using slot-type photoelectric sensors in the prior art, the utility model requires a smaller installation space and is not easily restricted by space. At the same time, the Hall sensor is not affected by the transparency of the microfluidic chip body. BRIEF DESCRIPTION OF THE DRAWINGS

[0026] The present invention will be further described in detail below in conjunction with the accompanying drawings and specific implementation methods, and the above and / or other advantages of the present invention will become more clear.

[0027] Figure 1 The present invention is a schematic diagram of a three-dimensional structure of an initial position positioning device for a microfluidic chip disclosed in an embodiment of the present invention.

[0028] Figure 2 for Figure 1 A front view of the initial position positioning device for a microfluidic chip is shown.

[0029] The description of the accompanying drawings is:

[0030] 1. Microfluidic chip; 11. Rotation axis; 12. Peripheral edge; 13. Groove; 14. Reaction chamber; 2. Magnetic component; 21. Path; 3. Hall sensor; 4. Drive motor; 5. Gap; 6. Chip fixing axis. DETAILED DESCRIPTION

[0031] In order to solve the above technical problems, the utility model discloses an initial position positioning device for a microfluidic chip, which comprises a microfluidic chip 1, a magnetic component 2, a Hall sensor 3 and a driving motor 4.

[0032] See now Figure 1 The microfluidic chip 1 has a rotation axis 11. The magnetic component 2 is fixedly arranged on the microfluidic chip 1. The Hall sensor 3 is installed near the periphery of the microfluidic chip 1 to detect the magnetic component 2. The drive motor 4 is configured to drive the microfluidic chip 1 and the magnetic component 2 to rotate synchronously around the rotation axis 11. The device is configured to stop the drive motor 4 when the Hall sensor 3 detects the magnetic component 2 to place the microfluidic chip 1 in the initial position.

[0033] Preferably, now see Figure 2 , the magnetic component 2 is located at the peripheral edge 12 of the microfluidic chip 1 .

[0034] This embodiment can effectively improve the positioning accuracy by placing the magnetic component at the outer peripheral edge 12 of the microfluidic chip 1, because the larger the radius and the larger the circumference, the smaller the ratio of the positioning error to the circumference, and thus the smaller the angular positioning error.

[0035] Specifically, see now Figure 2 The microfluidic chip 1 includes a groove 13 for carrying the magnetic component 2. More specifically, the groove 13 is arranged on the upper surface of the peripheral edge 12 of the microfluidic chip 1.

[0036] Specifically, see now Figure 2 , there is a gap 5 between the Hall sensor 3 and the magnetic component 2 .

[0037] Specifically, see now Figure 1 The Hall sensor 3 is located on a path 21 along which the magnetic component 2 rotates around the rotation axis 11 .

[0038] Specifically, see now Figure 2 The device includes a chip fixing shaft 6, the bottom end of the chip fixing shaft 6 is drivingly connected to the driving motor 4, and the top of the chip fixing shaft 6 is detachably connected to the microfluidic chip 1.

[0039] Specifically, the microfluidic chip 1 is a disk chip or a fan-shaped chip. Figure 2 , Figure 2 The microfluidic chip 1 in the embodiment is a disk-type chip.

[0040] Specifically, the magnetic component 2 can be a magnetic metal such as a magnet. The Hall sensor 3 can be a commercially available product with a model number of CD6-20NO-5 to match the magnet.

[0041] Specifically, see now Figure 1 The microfluidic chip 1 includes more than one reaction chamber 14 , and the more than one reaction chamber 14 is evenly spaced and distributed around the rotation axis 11 .

[0042] Below, refer to Figure 1 to Figure 2 , the method for using the initial position positioning device for a microfluidic chip of the utility model shown in Implementation 1 in the process of positioning the chip to the initial position is described:

[0043] First, the microfluidic chip 1 is clamped on the top of the chip fixing shaft 6 .

[0044] Then, the drive motor 4 is started to rotate, and the drive motor 4 drives the microfluidic chip 1 and the magnetic component 2 to rotate. When the magnetic component 2 passes through the Hall sensor 3, the magnetic field at the Hall sensor 3 changes, thereby causing the signal of the Hall sensor 3 to change, thereby triggering the device to control the drive motor 4 to stop, so as to place the microfluidic chip 1 in the initial position.

[0045] Since the positions of the magnetic component 2 and each reaction chamber 14 in the microfluidic chip 1 are relatively fixed, when the microfluidic chip 1 is accurately positioned at the initial position, the initial position is used as a reference to facilitate the subsequent accurate positioning of the relative positions of all reaction chambers 14. For example, in the case where multiple reaction chambers 14 are evenly spaced around the rotation axis 11, the drive motor 4 is controlled to run a rotation mode with a fixed angle each time, so that each reaction chamber 14 passes through a detection device for detecting the reaction condition in turn.

[0046] The utility model provides a concept and method for an initial position positioning device for a microfluidic chip. There are many methods and ways to implement the technical solution. The above is only a preferred implementation of the utility model. It should be pointed out that for ordinary technicians in this technical field, several improvements and modifications can be made without departing from the principle of the utility model. These improvements and modifications should also be regarded as the protection scope of the utility model. All components not specified in this embodiment can be implemented by existing technologies.

Claims

1. An initial position positioning device for a microfluidic chip, characterized in that: include: A microfluidic chip (1) having a rotation axis (11); A magnetic component (2) fixedly arranged on the microfluidic chip (1); A Hall sensor (3) is installed near the periphery of the microfluidic chip (1) to detect the magnetic component (2); and a drive motor (4), wherein the drive motor (4) is configured to drive the microfluidic chip (1) and the magnetic component (2) to rotate synchronously around the rotation axis (11); The device is configured to stop the driving motor (4) when the Hall sensor (3) detects the magnetic component (2) so as to place the microfluidic chip (1) in an initial position.

2. The initial position positioning device for a microfluidic chip according to claim 1, characterized in that: The magnetic component (2) is located at the peripheral edge (12) of the microfluidic chip (1).

3. The initial position positioning device for a microfluidic chip according to claim 2, characterized in that: The microfluidic chip (1) comprises a groove (13) for carrying the magnetic component (2).

4. The initial position positioning device for a microfluidic chip according to claim 3, characterized in that: The groove (13) is arranged on the upper surface of the peripheral edge (12) of the microfluidic chip (1).

5. The initial position positioning device for a microfluidic chip according to claim 1 or 2, characterized in that: There is a gap (5) between the Hall sensor (3) and the magnetic component (2).

6. The initial position positioning device for a microfluidic chip according to claim 1 or 2, characterized in that: The Hall sensor (3) is located on a path (21) along which the magnetic component (2) rotates around the rotation axis (11).

7. The initial position positioning device for a microfluidic chip according to claim 1 or 2, characterized in that: It comprises a chip fixing shaft (6), the bottom end of the chip fixing shaft (6) is drivingly connected to the driving motor (4), and the top end of the chip fixing shaft (6) is detachably connected to the microfluidic chip (1).

8. The initial position positioning device for a microfluidic chip according to claim 1 or 2, characterized in that: The microfluidic chip (1) is a disc-shaped chip or a sector-shaped chip.

9. The initial position positioning device for a microfluidic chip according to claim 1 or 2, characterized in that: The magnetic component is a magnet.

10. The initial position positioning device for a microfluidic chip according to claim 1 or 2, characterized in that: The microfluidic chip (1) comprises one or more reaction chambers (14), and the one or more reaction chambers (14) are evenly spaced and distributed around the rotation axis (11).

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