Mouse anesthesia device for laboratory

By designing adjustable mouse anesthesia equipment, the mouse anesthesia equipment in existing technology cannot meet the problems of anesthesia before and during surgery, and realizes the supply of continuous anesthesia in the operation and better anesthesia effects.

CN222383422UActive Publication Date: 2025-01-24CHANGCHUN UNIV OF CHINESE MEDICINE
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Patent Information

Application Number
CN202423223086.2
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-12-26
Publication Date
2025-01-24
Estimated Expiration
2034-12-26

AI Technical Summary

Technical Problem

The existing mouse anesthesia equipment cannot meet the anesthesia needs of mice both before and during the operation, resulting in poor anesthesia results.

Method used

A laboratory mouse anesthesia equipment is designed, which includes a surgical fixation plate and an anesthesia shell. An air outlet is provided at one end of the anesthesia shell, and a fixation rod is provided on the upper side of the surgical fixation plate. The anesthesia shell and the surgical fixation plate can slide relative to each other to adjust the anesthetic agent. supply.

Benefits of technology

By adjusting the relative distance between the anesthesia shell and the mouse, continuous anesthetic supply during the operation is achieved, the anesthetic effect is improved, and the impact of insufficient or excessive anesthesia dose on the mouse is avoided.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses mouse anesthesia equipment for a laboratory, and relates to the technical field of structural design of laboratory operation equipment. Comprising an operation fixing plate and an anesthetic shell. The operation fixing plate is slidably connected with the anesthetic shell; an air outlet is formed in one end of the anesthetic shell, and a fixing rod is arranged on the upper side of the operation fixing plate outside the air outlet. According to the mouse anesthesia instrument for the laboratory, a mouse before an operation can be anesthetized through the anesthesia shell, the mouse during the operation can be fixed through the operation fixing plate, anesthetic can be continuously supplied to the mouse through the anesthesia shell, it is guaranteed that the anesthetic is continuously supplied to the mouse during the operation, and the anesthesia effect during the operation is improved; furthermore, the anesthetic shell and the operation fixing plate can slide relatively, so that the relative distance between the anesthetic shell and the mouse in the operation is adjusted, the distance between the anesthetic shell and the mouse is adjusted in time according to vital signs of the mouse, and the supply amount of anesthetic is adjusted.
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Description

Technical Field

[0001] The utility model relates to the technical field of laboratory surgical equipment structure design, in particular to a laboratory mouse anesthesia equipment. Background Art

[0002] Mouse anesthesia machines are widely used in the fields of neuroscience research, pharmacology and toxicology research, genetics and developmental biology research, etc. In experiments such as brain function localization, neural pathway tracing, new drug screening, drug toxicity evaluation, gene editing, and embryo transplantation, they provide a stable anesthesia state for mouse anesthesia, ensuring the smooth progress of delicate surgical operations, while avoiding the influence of stress reactions in awake animals on experimental results.

[0003] In the prior art, only a single method is used to anesthetize mice before surgery. There is no stable anesthesia supply for mice during surgery, which easily leads to insufficient anesthesia dosage, causing mice to wake up from anesthesia, affecting the effect of surgery. If too much anesthetic is used before surgery, it is easy to affect the vital characteristics of mice and affect the experimental effect.

[0004] It can be seen that in the prior art, the mouse anesthesia equipment cannot meet the requirements of anesthesia for mice both before and during surgery, and the anesthesia effect is poor. Utility Model Content

[0005] In view of this, the main purpose of the utility model is to provide a laboratory mouse anesthesia equipment that can adjust the relative distance between the anesthesia shell and the mouse during surgery, and timely adjust the distance between the anesthesia shell and the mouse according to the life characteristics of the mouse, thereby adjusting the supply of anesthetic.

[0006] In order to achieve the above object, the technical solution of the utility model is implemented as follows:

[0007] A laboratory mouse anesthesia equipment comprises: a surgical fixing plate and an anesthesia shell, wherein the surgical fixing plate is slidably connected to the anesthesia shell; an air outlet is arranged at one end of the anesthesia shell, and a fixing rod is arranged on the upper side of the surgical fixing plate outside the air outlet.

[0008] In a preferred embodiment, an anesthesia cylinder assembly is fixedly connected inside the air outlet.

[0009] In a preferred embodiment, the anesthesia cylinder assembly includes: an extension cylinder, a limiting sleeve, an extension sleeve and a compression spring. The extension cylinder extends into the air outlet, and the limiting sleeve is fixedly connected to the outer wall of one end extending into the air outlet, and the other end of the extension cylinder is fixedly connected to the extension sleeve, and the compression spring is arranged between the extension sleeve and the outer wall of the anesthesia shell.

[0010] In a preferred embodiment, it further comprises: a protective sleeve, one end of which is fixedly connected to the end of the extending sleeve, the protective sleeve is sleeved on the outer wall of the compression spring, and the length of the protective sleeve is less than the length of the extension tube.

[0011] In a preferred embodiment, the surgical fixation plate comprises: a fixation plate body and two guide plates, one side of the fixation plate body is fixedly connected to the guide plate, and the two guide plates are limitedly and guidely connected to the anesthesia shell.

[0012] In a preferred embodiment, a guide protrusion is provided on one side of the guide plate close to the anesthesia shell, guide grooves are provided on both sides of the bottom of the anesthesia shell, and the guide protrusion is slidably connected inside the guide groove.

[0013] In a preferred embodiment, a limiting component is provided on one side of the guide plate close to the anesthesia shell, a limiting groove is provided on the outer wall of the anesthesia shell, and the limiting component extends into the limiting groove to limit the position of the anesthesia shell.

[0014] In a preferred embodiment, a limiting cavity is provided on a side of the guide plate close to the anesthesia shell, and the limiting assembly is connected to the inside of the limiting cavity.

[0015] In a preferred embodiment, the limiting assembly includes: a guide rod, a positioning plate, a limiting protrusion and a pushing spring, one end of the guide rod is fixedly connected to the limiting protrusion, one end of the guide rod close to the limiting protrusion is threadedly connected to the positioning plate, and the pushing spring is sleeved on the outer wall of the guide rod.

[0016] In a preferred embodiment, the guide rod extends into the bottom of the limiting cavity, and a mounting slot is provided on the lower side of the limiting cavity through the positioning plate, and the width of the mounting slot is greater than the thickness of the positioning plate, so that the positioning plate is installed inside the limiting cavity along the mounting slot, and the positioning plate can slide inside the mounting slot.

[0017] In a preferred embodiment, the positioning plate is a square plate, and the upper side of the mounting slot is a square structure, so that the mounting slot limits the rotation of the positioning plate.

[0018] In a preferred embodiment, a mouse entrance hole is provided at one end of the anesthesia shell away from the air outlet, and a mouse door is hinged inside the mouse entrance hole.

[0019] In a preferred embodiment, a cover plate is hingedly connected to the upper side of the anesthesia shell.

[0020] The laboratory mouse anesthesia equipment of the utility model has the following beneficial effects:

[0021] The laboratory mouse anesthesia equipment comprises: a surgical fixing plate and an anesthesia shell, wherein the surgical fixing plate is slidably connected to the anesthesia shell; an air outlet is arranged at one end of the anesthesia shell, and a fixing rod is arranged on the upper side of the surgical fixing plate outside the air outlet.

[0022] The defect in the prior art that the mouse anesthesia equipment cannot meet the requirements of anesthesia for mice both before and during surgery and the anesthesia effect is poor is solved.

[0023] The mouse anesthesia equipment used in the laboratory can anesthetize mice before surgery through an anesthesia shell, fix mice during surgery through a surgical fixation plate, and continuously supply anesthetics to mice through the anesthesia shell to ensure continuous supply of anesthetics to mice during surgery and improve the anesthesia effect during surgery; further, the anesthesia shell and the surgical fixation plate can slide relative to each other, thereby adjusting the relative distance between the anesthesia shell and the mouse during surgery, and timely adjusting the distance between the anesthesia shell and the mouse according to the life characteristics of the mouse, thereby adjusting the supply of anesthetics. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] Figure 1 It is a schematic structural diagram of a laboratory mouse anesthesia device according to one embodiment of the present disclosure;

[0025] Figure 2 It is a schematic structural diagram of another angle of the laboratory mouse anesthesia equipment according to one embodiment of the present disclosure;

[0026] Figure 3 It is a front view of a laboratory mouse anesthesia device according to one embodiment of the present disclosure;

[0027] Figure 4 A side view of an anesthesia device for laboratory mice according to one embodiment of the present disclosure;

[0028] Figure 5 It is a schematic structural diagram of an anesthesia shell of an anesthesia device for mice in a laboratory according to one embodiment of the present disclosure;

[0029] Figure 6 It is a cross-sectional view of a laboratory mouse anesthesia device at a limiting component according to an embodiment of the present disclosure;

[0030] Figure 7 It is a schematic structural diagram of a guide plate of a laboratory mouse anesthesia device according to one embodiment of the present disclosure;

[0031] Figure 8 A bottom view of a guide plate of a laboratory mouse anesthesia device according to an embodiment of the present disclosure;

[0032] Fig. 9It is a structural schematic diagram of an anesthesia cylinder assembly of a laboratory mouse anesthesia device according to one embodiment of the present disclosure;

[0033] Fig.10 An exploded view of an anesthesia cylinder assembly of a laboratory mouse anesthesia device according to one embodiment of the present disclosure;

[0034] Fig.11 It is a cross-sectional view of an anesthesia cylinder assembly of a laboratory mouse anesthesia device according to one embodiment of the present disclosure;

[0035] Fig.12 The present invention is a schematic structural diagram of a limiting component of a laboratory mouse anesthesia device according to an embodiment of the present invention.

[0036]

Main component symbol description

[0037] 1. Surgical fixation plate;

[0038] 11. Fixed plate body; 12. Guide plate; 13. Guide protrusion;

[0039] 2. Anesthesia shell;

[0040] 21. air outlet; 22. guide groove; 23. limit groove;

[0041] 24. Limiting cavity; 25. Installation notch;

[0042] 26. Entering a rat hole;

[0043] 3. Fixing rod;

[0044] 4. Anesthesia cylinder assembly;

[0045] 41. extension tube; 42. limiting sleeve; 43. extension sleeve; 44. compression spring; 45. protective sleeve;

[0046] 5. Limiting components;

[0047] 51. Guide rod; 52. Positioning plate; 53. Limiting protrusion; 54. Push spring;

[0048] 6. Close the rat door; 7. Cover the plate. DETAILED DESCRIPTION

[0049] The laboratory mouse anesthesia equipment of the present invention will be further described in detail below in conjunction with the accompanying drawings and embodiments of the present invention.

[0050] like Figure 1-Figure 12As shown, the laboratory mouse anesthesia equipment includes: a surgical fixing plate 1 for fixing mice during experimental surgery; an anesthesia shell 2 for anesthetizing mice before and during surgery; in order to facilitate the adjustment of the position of the anesthesia shell 2 relative to the surgical fixing plate 1, so that mice of different body sizes can use the same anesthesia equipment, the surgical fixing plate 1 is slidably connected to the anesthesia shell 2, and the position of the anesthesia equipment relative to the surgical fixing plate 1 is adjusted according to the body size of different mice, so as to ensure the amount of anesthetic inhaled by the mouse during the mouse surgery. Similarly, it can also conveniently meet the needs of the surgeon to adjust the distance of the anesthesia shell 2 according to the state of the mouse during the operation, and then adjust the dosage of the anesthetic ingested by the mouse, so as to ensure the smooth progress of the experimental surgery.

[0051] In order to ensure the release of the anesthetic inside the anesthesia shell 2, an air outlet 21 is provided at one end of the anesthesia shell 2, and a fixing rod 3 (the fixing rod 3 can be a threaded rod, which is threadedly connected to the surgical fixing plate 1) is fixedly connected to the upper side of the surgical fixing plate 1 outside the air outlet 21. After the mouse is anesthetized, one side of the mouse's nostril is placed close to the air outlet 21, so that the mouse can be guaranteed to take in a certain amount of anesthetic for a long time during the mouse surgery.

[0052] In order to extend the extension distance of the air outlet 21, and at the same time, when the mouse has an abnormal collision, the position of the air outlet 21 can be somewhat extended to ensure that the air outlet position of the air outlet 21 is close to the mouse, thereby improving the anesthesia effect. The air outlet 21 is fixedly connected with an anesthesia cylinder assembly 4.

[0053] In order to realize the telescopic rebound effect of the part of the anesthesia tube assembly 4 extending out of the air outlet 21, the anesthesia tube assembly 4 includes: an extension tube 41 extending out of the air outlet 21, a limiting sleeve 42 limiting the inner wall of the anesthesia shell 2, an extension sleeve 43 supporting the compression spring 44 outside the anesthesia shell 2, and a compression spring 44 supporting the extension sleeve 43. The extension tube 41 extends into the air outlet 21, and the limiting sleeve 42 is fixedly connected to the outer wall of the end extending into the air outlet 21 (preferably, the limiting sleeve 42 is threadedly connected to the outer wall of the extension tube 41), and the other end of the extension tube 41 is fixedly connected to the extension sleeve 43, and a compression spring 44 is arranged between the extension sleeve 43 and the outer wall of the anesthesia shell 2. The compression spring 44 supports the extension sleeve 43 to extend a certain distance, and the compression spring 44 is in a compressed state, supporting the extension sleeve 43 to be in an extended position.

[0054] When the mouse shakes abnormally, or the experimenter touches the extension sleeve 43 during the operation, the entire anesthesia cylinder assembly 4 can compress the compression spring 44 and shrink, and can recover naturally, ensuring that the relative distance between the anesthesia cylinder assembly 4 and the mouse remains unchanged, thereby ensuring the anesthetic effect of the mouse.

[0055] In order to cover the compression spring 44 and reduce the exposed size of the compression spring 44, it also includes: a protective sleeve 45, one end of which is fixedly connected to the end of the extension sleeve 43, and the protective sleeve 45 is sleeved on the outer wall of the compression spring 44. At the same time, in order to prevent the protective sleeve 45 from affecting the telescopic size of the extension tube 41, the length of the protective sleeve 45 is smaller than the length of the extension tube 41.

[0056] In order to satisfy the function of the surgical fixing plate 1 to fix the mouse during the operation and to limit and adjust the anesthesia shell 2, the surgical fixing plate 1 includes: a fixing plate body 11 for fixing the mouse and two guide plates 12 for adjusting the position of the anesthesia shell 2. One side of the fixing plate body 11 is fixedly connected to the guide plate 12, and the two guide plates 12 are connected to the anesthesia shell 2 by limiting the guide connection. The fixing rod 3 is fixedly connected to the upper side of the fixing plate body 11. In order to satisfy the sliding of the anesthesia shell 2, it can also be ensured that the anesthesia shell 2 will not separate from the guide plate 12. A guide protrusion 13 is provided on the side of the guide plate 12 close to the anesthesia shell 2, and guide grooves 22 are provided on both sides of the bottom of the anesthesia shell 2, and the guide protrusion 13 is slidably connected inside the guide groove 22.

[0057] In order to ensure that the position of the anesthesia shell 2 can be limited during the sliding process, that is, when the anesthesia shell 2 slides to the set position, it can be relatively fixed. A limiting component 5 is provided on the side of the guide plate 12 close to the anesthesia shell 2, and a limiting groove 23 is provided on the outer wall of the anesthesia shell 2. The limiting component 5 extends into the limiting groove 23 to limit the position of the anesthesia shell 2. The limiting component 5 and the limiting groove 23 are structurally adapted to ensure the limiting effect.

[0058] In order to facilitate the installation of the limit assembly 5 and to facilitate its extension, the experimenter can manually push the limit assembly 5 to slide. The guide plate 12 is provided with a limit cavity 24 on one side close to the anesthesia shell 2, and the limit assembly 5 is limit-connected inside the limit cavity 24.

[0059] The limiting assembly 5 includes: a guiding rod 51 for guiding, a positioning plate 52 for limiting the entire limiting assembly 5 in the limiting cavity 24, a limiting protrusion 53 for cooperating with the anesthesia shell 2 for limiting, and a pushing spring 54 for pushing the entire limiting assembly 5 out of the limiting cavity 24. One end of the guide rod 51 is fixedly connected to the limiting protrusion 53, and one end of the guide rod 51 close to the limiting protrusion 53 is threadedly connected to the positioning plate 52, and the pushing spring 54 is sleeved on the outer wall of the guide rod 51. The positioning plate 52 is pushed by the pushing spring 54, and the limiting protrusion 53 is extended along the limiting cavity 24 to limit the anesthesia shell 2.

[0060] The guide rod 51 extends into the bottom of the limiting cavity 24, and an installation slot 25 is provided on the lower side of the limiting cavity 24 through the positioning plate 52. The width of the installation slot 25 is greater than the thickness of the positioning plate 52, so that the positioning plate 52 can be installed inside the limiting cavity 24 along the installation slot 25, and the positioning plate 52 can slide inside the installation slot 25 (the positioning plate 52 can move along the length direction of the limiting cavity 24); the specific installation process is: the positioning plate 52 extends into the limiting cavity 24 along the installation slot 25, the guide rod 51 and the limiting protrusion 53 extend along the limiting cavity 24, the guide rod 51 passes through the threaded hole opened in the center of the positioning plate 52, and when the guide rod 51 is close to the external thread and threaded hole at one end of the limiting protrusion 53, the guide rod 51 is rotated and the limiting protrusion 53 is threadedly connected to ensure that the larger positioning plate 52 is smoothly installed.

[0061] In order to ensure that the positioning plate 52 does not rotate, the guide rod 51 can be threadedly connected to the positioning plate 52. The positioning plate 52 is a square plate, and the upper side of the installation slot 25 is a square structure, so that the installation slot 25 limits the rotation of the positioning plate 52.

[0062] In order to facilitate mice to enter the anesthesia shell 2, a mouse entrance hole 26 is provided at one end of the anesthesia shell 2 away from the air outlet 21, and a mouse door 6 is hinged inside the mouse entrance hole 26. The mouse is locked inside the anesthesia shell 2 by closing the mouse door 6.

[0063] The mouse after anesthesia can be conveniently taken out, and a cover plate 7 is hinged on the upper side of the anesthesia shell 2. The anesthesia shell 2 is opened through the cover plate 7, and the mouse anesthetized inside the anesthesia shell 2 is taken out, and the surgery is fixed by inserting the fixing rod 3.

[0064] The above description is only a preferred embodiment of the present invention and is not intended to limit the protection scope of the present invention.

Claims

1. A laboratory mouse anesthesia device, characterized in that: include: A surgical fixation plate (1) and an anesthesia shell (2), wherein the surgical fixation plate (1) is slidably connected to the anesthesia shell (2); An air outlet hole (21) is provided at one end of the anesthesia shell (2), and a fixing rod (3) is provided on the upper side of the surgical fixing plate (1) outside the air outlet hole (21).

2. The laboratory mouse anesthesia equipment according to claim 1, characterized in that: An anesthesia cylinder assembly (4) is fixedly connected inside the air outlet hole (21); The anesthesia cylinder assembly (4) comprises: an extension cylinder (41), a limiting sleeve (42), a protruding sleeve (43) and a compression spring (44); the extension cylinder (41) extends into the air outlet hole (21), and the outer wall of one end extending into the air outlet hole (21) is fixedly connected to the limiting sleeve (42); the other end of the extension cylinder (41) is fixedly connected to the protruding sleeve (43); and the compression spring (44) is arranged between the protruding sleeve (43) and the outer wall of the anesthesia shell (2).

3. The laboratory mouse anesthesia equipment according to claim 2, characterized in that: Also includes: A protective sleeve (45), one end of which is fixedly connected to the end of the extension sleeve (43), the protective sleeve (45) is sleeved on the outer wall of the compression spring (44), and the length of the protective sleeve (45) is less than the length of the extension tube (41).

4. The laboratory mouse anesthesia equipment according to any one of claims 1 to 3, characterized in that: The surgical fixation plate (1) comprises: a fixation plate body (11) and two guide plates (12); one side of the fixation plate body (11) is fixedly connected to the guide plate (12); and the two guide plates (12) are position-limitingly and guidely connected to the anesthesia shell (2).

5. The laboratory mouse anesthesia equipment according to claim 4, characterized in that: A guide protrusion (13) is provided on one side of the guide plate (12) close to the anesthesia shell (2), and guide grooves (22) are provided on both sides of the bottom of the anesthesia shell (2), and the guide protrusion (13) is slidably connected inside the guide groove (22).

6. The laboratory mouse anesthesia equipment according to claim 5, characterized in that: A limiting component (5) is provided on a side of the guide plate (12) close to the anesthesia shell (2), a limiting groove (23) is provided on the outer wall of the anesthesia shell (2), and the limiting component (5) extends into the limiting groove (23) to limit the position of the anesthesia shell (2).

7. The laboratory mouse anesthesia equipment according to claim 6, characterized in that: A limiting cavity (24) is provided on a side of the guide plate (12) close to the anesthesia shell (2), and the limiting component (5) is connected to the inside of the limiting cavity (24) in a limiting manner; The limiting assembly (5) comprises: a guide rod (51), a positioning plate (52), a limiting protrusion (53) and a pushing spring (54); one end of the guide rod (51) is fixedly connected to the limiting protrusion (53); one end of the guide rod (51) close to the limiting protrusion (53) is threadedly connected to the positioning plate (52); and the pushing spring (54) is sleeved on the outer wall of the guide rod (51).

8. The laboratory mouse anesthesia equipment according to claim 7, characterized in that: The guide rod (51) extends into the bottom of the limiting cavity (24); a mounting slot (25) is provided on the lower side of the limiting cavity (24) and passes through the positioning plate (52); the width of the mounting slot (25) is greater than the thickness of the positioning plate (52), so that the positioning plate (52) is installed inside the limiting cavity (24) along the mounting slot (25), and the positioning plate (52) can slide inside the mounting slot (25); The positioning plate (52) is a square plate, and the upper side of the mounting slot (25) is a square structure, so that the mounting slot (25) limits the rotation of the positioning plate (52).

9. The laboratory mouse anesthesia equipment according to claim 1, characterized in that: A mouse entrance hole (26) is provided at one end of the anesthesia shell (2) away from the air outlet (21), and a mouse door (6) is hinged inside the mouse entrance hole (26).

10. The laboratory mouse anesthesia equipment according to claim 1, characterized in that: A cover plate (7) is hingedly connected to the upper side of the anesthesia shell (2).