Drug aerosol delivery device and air supply system thereof

Abstract

The utility model provides a drug aerosol delivery device and an air supply system thereof. The drug aerosol delivery device comprises a drug bomb assembly used for generating drug aerosol, an aerosol channel used for containing the aerosol is defined in the drug bomb assembly, and the aerosol channel is provided with an air inlet and an air outlet; the air supply system is provided with: a flow generator for generating a set amount of air flow; and the air gathering cover is communicated with the flow generator and the air inlet so as to gather the set amount of air flow and convey the gathered air flow into the aerial fog channel. The air supply system of the device can generate a set amount of air flow and accurately deliver drug aerosol into the respiratory tract of a patient, so that accurate and quantitative drug administration is realized. The utility model further provides a drug aerosol delivery device which has the advantages of being small and exquisite in structure, convenient to carry and accurate in drug delivery.

Description

Technical Field

[0001] The utility model relates to the technical field of atomization drug delivery, in particular to a drug aerosol delivery device and an air supply system thereof. Background Art

[0002] Nasal / oral inhalation is a very special route of administration that can be used to prevent and treat diseases of the central nervous system, respiratory system and other areas. (1) Studies have confirmed that there is a direct anatomical channel between brain tissue and nasal cavity. Intranasal administration bypasses the blood-brain barrier and directly delivers drugs to the brain non-invasively. That is, drugs can reach the central nervous system through the olfactory epithelium or respiratory epithelium of the nasal mucosa, quickly enter the brain tissue and interact with relevant receptors to produce therapeutic effects. The nose-brain connection can also trigger and regulate the olfactory-amygdala neural circuit by activating peripheral nasal chemosensory neurons without the need for drugs to directly bind to neuronal receptors in the brain central nervous system, thereby limiting the transport of molecules to the blood circulation system and minimizing the potential systemic exposure of drugs. Regardless of the mechanism, its characteristics are to avoid the blood-brain barrier, alveolar blood-gas barrier, liver first-pass effect and gastrointestinal metabolism, so the required dose is the lowest (10-6-10-12g), the onset is the fastest (a few seconds), the systemic toxicity and side effects are the lowest, and the compliance is the best. (2) Studies have confirmed that lung absorption is also a good route of administration. The characteristics of lung-targeted drugs are: large absorption surface area, rich capillary network, and thin alveolar gas-blood barrier, which can avoid gastrointestinal metabolism and liver first-pass effect; lower doses than oral and injection administration, faster onset, less systemic toxicity and side effects, and better compliance. (3) Studies have confirmed that other non-central nervous system and non-respiratory system drugs can also achieve better prevention and treatment effects of diseases through nasal / oral atomization inhalation administration, such as peptide diabetes drugs that require frequent injections, osteoporosis drugs, hormone drugs, and other oral and injectable drugs that require rapid onset. Improvement into an inhalation dosage form to meet user needs has very practical significance.

[0003] Nebulizer inhalation dosage forms refer to preparations in which drugs are administered using a special device and inhaled through the deep respiratory tract, cavities, mucous membranes, etc. to exert local or systemic therapeutic effects, thereby achieving the purpose of painless, rapid and effective treatment.

[0004] Respiratory inhalation compositions can be divided into liquid nebulizer inhalers, metered dose inhalation aerosols, dry powder inhalers and soft mists. Liquid nebulizer inhalers, as a specific dosage form for respiratory administration, are usually aqueous solutions. A specific device is used to convert inhalable drugs into aerosols for patients to inhale. The inhaled drug dose is deposited at different lesion sites in the respiratory tract at a certain rate and appropriate particle size. The particle size of the aerosol has been widely studied by researchers as an important factor that mainly affects the deposition site of respiratory administration; another factor is the user's inhalation strength and breathing habits. The same nebulizer and drug nebulizer will produce different inhaled drug doses and drug deposition in different parts for different patients, thus producing different therapeutic effects. Aerosols, dry powder inhalers and soft mists have the same problem of inaccurate nebulization dose, inhalation dose and deposition site.

[0005] For example, the Chinese utility model patent with the authorization announcement number CN203736645U discloses a handheld high-frequency ultrasonic atomization whole respiratory tract drug introduction device, which includes a shell with an air inlet and a cover with a mist outlet. A medicine cup with an atomizing sheet and an atomizing cover with a mist outlet on the top of the shell are arranged inside the shell. A fluid flow channel is formed between the air inlet, the mist outlet and the mist outlet, and a fan is also arranged near the air inlet. Fig.12 As shown, there is an open space between the fan and the medicine cup in this patent, and the wind blown by the fan leaks and cannot completely enter the medicine cup to deliver the medicine, resulting in low accuracy of drug delivery, thereby affecting the patient's treatment effect.

[0006] In view of this, it is necessary to propose a new technical solution to overcome the problems existing in the prior art. Utility Model Content

[0007] In order to solve the problems existing in the prior art, on the one hand, the utility model provides an air supply system applied to a drug aerosol delivery device, in which an air collecting hood is arranged between the flow generator and the aerosol channel, which can prevent the air volume generated by the flow generator from leaking, thereby realizing accurate quantitative delivery of drug aerosol and improving the treatment effect.

[0008] On the other hand, the utility model provides a drug aerosol delivery device, including the above-mentioned air supply system, which has the advantages of compact structure, easy to carry and accurate drug delivery.

[0009] The utility model adopts the following technical solutions:

[0010] On the one hand, the utility model provides an air supply system for a drug aerosol delivery device, the drug aerosol delivery device comprising: a drug cartridge assembly for generating drug aerosol, an aerosol passage for receiving the aerosol is defined in the drug cartridge assembly, the aerosol passage has an air inlet and an air outlet; the air supply system has:

[0011] a flow generator for generating a set amount of air flow; and

[0012] The air gathering hood is connected to the flow generator and the air inlet to gather the set amount of air flow and then transport it to the aerosol channel.

[0013] Furthermore, in the area between the flow generator and the ammunition assembly, the wind gathering hood has a portion with a gradually decreasing cross-sectional area to gather the air flow.

[0014] Furthermore, the air outlet end of the air collecting hood is configured to be suitable for docking with the air inlet.

[0015] Furthermore, the ammunition cartridge assembly includes a sealing base, the air inlet is formed on the sealing base, and the air outlet end of the air collecting hood is in sealing contact with the sealing base.

[0016] Furthermore, it is provided with: a drug cartridge sleeve, wherein the drug cartridge assembly is detachably attached to the drug cartridge sleeve;

[0017] The bottom of the cartridge case is provided with a positioning hole, and the positioning hole is suitable for defining the position of the wind gathering cover.

[0018] Furthermore, the air outlet end of the air collecting cover passes through the positioning hole and then connects to the air inlet.

[0019] Furthermore, the cartridge case has at least one positioning column, and the flow generator and the wind gathering cover are both fixedly connected to the positioning column.

[0020] Further, the positioning column extends toward a side close to the flow generator.

[0021] Furthermore, the flow generator and the wind collecting hood are sealed and connected.

[0022] Furthermore, the flow generator is a quantitative fan.

[0023] Furthermore, the air volume of the flow generator is 1.0-50 ml / s.

[0024] Furthermore, it also includes a control device, which is configured to drive the flow generator to generate a set amount of airflow according to an operation instruction.

[0025] On the other hand, the utility model also provides a drug aerosol delivery device, including a shell, a drug cartridge assembly and an air supply system, wherein the air supply system is the above-mentioned air supply system.

[0026] By adopting the above technical solution, the utility model has the following technical effects:

[0027] 1. The device is equipped with a wind collecting hood between the flow generator and the aerosol channel, which can prevent the air volume generated by the flow generator from leaking, so that the air flow generated by the flow generator can be completely delivered into the atomization chamber to deliver the drug aerosol to the patient's respiratory tract, thereby achieving accurate quantitative delivery of the drug aerosol and improving the treatment effect.

[0028] 2. In the prior art, in order to increase the delivery pressure of drug aerosol delivery, the cross-sectional area of ​​the aerosol channel is usually set to be small, while the cross-sectional area of ​​the air outlet of the flow generator, especially the fan, is large. The difference between the cross-sectional areas is large, which makes it impossible for the wind generated by the fan to fully enter the aerosol channel, causing turbulence at the air outlet of the fan, and then leading to the problem of trapped air. In order to solve the above technical problems, the device is provided with a wind collecting hood with a gradually decreasing cross-sectional area. The wind collecting hood can fully receive the airflow generated by the flow generator and gradually pressurize it to deliver it to the aerosol channel, thereby ensuring the stability of the air flow input.

[0029] 3. The flow generator in this device is a quantitative fan, and the air volume can be adjusted in the range of 1.0 to 50 ml / s. It can not only realize quantitative air supply, but also flexibly adjust the air volume according to the medication needs of different patients or different stages, so that the drug delivery device can accurately and quantitatively deliver drugs according to medication needs, thereby improving the drug treatment effect.

[0030] 4. The utility model also provides a drug aerosol delivery device, which has the advantages of compact structure, easy to carry, and accurate drug delivery. BRIEF DESCRIPTION OF THE DRAWINGS

[0031] In order to more clearly illustrate the technical solutions of the embodiments of the present utility model, the drawings of the embodiments will be briefly introduced below. Obviously, the drawings in the following description only relate to some embodiments of the present utility model, rather than limiting the present utility model.

[0032] Figure 1 It is a schematic diagram of the structure of the drug aerosol delivery device in the closed state.

[0033] Figure 2 It is a schematic diagram of the structure of the drug aerosol delivery device in the open cover state.

[0034] Figure 3 It is a schematic diagram of the structure of the drug aerosol delivery device with the left shell removed.

[0035] Figure 4 It is a schematic diagram of the structure of the drug aerosol delivery device with the right shell removed.

[0036] Figure 5 is an exploded schematic diagram of a drug aerosol delivery device.

[0037] Figure 6is a front cross-sectional view of a drug aerosol delivery device.

[0038] Figure 7 It is the main cross-sectional view of the ammunition assembly and the ammunition sleeve.

[0039] Figure 8 It is a schematic diagram of the structure of the ammunition component.

[0040] Fig. 9 This is a disassembled schematic diagram of the ammunition component.

[0041] Fig.10 It is a cross-sectional view of the ammunition assembly.

[0042] Fig.11 It is the distribution diagram of aerosol particles output by the ammunition component.

[0043] Fig.12 It is a structural diagram of an atomizer in the prior art.

[0044] Explanation of the reference numerals: 1-box cover; 2-shell; 2a-left shell; 2b-right shell; 2c-air inlet; 3-indicator light; 4-button; 5-cartridge assembly; 5a-cartridge shell; 5a1-mist nozzle; 5a2-aerosol channel; 5b-drug liquid holding part; 5d-atomizer; 5e-sealed base; 5e1-air inlet; 5f-electrode part; 6-cartridge sleeve; 6a-positioning hole; 6b-conductive connector; 7-wind gathering hood; 7a-conical hood body; 7b-tube body; 8-flow generator; 9-circuit board; 10-battery; 11-positioning column. DETAILED DESCRIPTION

[0045] In order to make the purpose, technical scheme and advantages of the embodiments of the utility model clearer, the utility model will be further described in detail below in conjunction with the accompanying drawings. The components of the embodiments of the utility model described and shown in the drawings herein can be arranged and designed in various different configurations. Based on the embodiments of the utility model, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the utility model.

[0046] It should be noted that similar reference numerals and letters denote similar items in the following drawings, and therefore, once an item is defined in one drawing, further definition and explanation thereof is not required in subsequent drawings.

[0047] Unless otherwise defined, the technical terms or scientific terms used in this patent document shall be the common meanings understood by people with ordinary skills in the field to which the utility model belongs. The words "first", "second" and similar words used in the utility model patent specification and claims do not indicate any order, quantity or importance, but are only used to distinguish different components. Similarly, words such as "one", "one" or "the" do not indicate a quantity limit, but indicate the existence of at least one. Words such as "include" or "comprise" mean that the elements or objects appearing before "include" or "comprise" include the elements or objects listed after "include" or "comprise" and their equivalents, and do not exclude other elements or objects. "Center", "upper", "lower", "left", "right", "vertical", "horizontal", "inside", "outside" and the like are only used to indicate relative positional relationships. When the absolute position of the described object changes, the relative positional relationship may also change accordingly. It is only for the convenience of describing the utility model and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on the utility model.

[0048] In the description of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms "installation", "connection" and "connection" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be indirectly connected through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0049] Some embodiments of the present invention are described in detail below in conjunction with the accompanying drawings. In the absence of conflict, the features of the following embodiments can be combined with each other.

[0050] See also Figures 1 to 11As shown, the utility model provides an air supply system for a drug aerosol delivery device, the drug aerosol delivery device comprising: a drug cartridge assembly 5 for generating drug aerosol, an aerosol channel 5a2 for receiving the aerosol is defined in the drug cartridge assembly 5, and the aerosol channel 5a2 has an air inlet 5e1 and an air outlet; the air supply system is provided with a flow generator 8 and a wind condenser 7, wherein the flow generator 8 is used to generate a set amount of air flow; the wind condenser 7 is used to connect the flow generator 8 and the air inlet 5e1, so as to gather the set amount of air flow and then deliver it to the aerosol channel 5a2, so as to achieve accurate drug aerosol delivery. Furthermore, it also includes a control device, which is configured to drive the flow generator 8 to generate a set amount of airflow according to an operation instruction, further improving the convenience of operation, so that the user can adjust the dosage according to the healing condition at different stages of the user, and improve the therapeutic effect of the drug.

[0051] like Figure 4-6 As shown, in the area between the flow generator 8 and the drug cartridge assembly 5, the air gathering hood 7 has a portion with a gradually decreasing cross-sectional area. Specifically, the air gathering hood 7 includes: a conical hood body 7a with a gradually decreasing cross-sectional area and a tube body 7b extending from the conical hood body 7a along the direction of air flow, the port of the tube body 7b forms an air outlet end, and the air outlet end is configured to be suitable for docking with the air inlet 5e1. The conical hood body 7a has a large cross-sectional area at one end close to the flow generator 8, and can fully accommodate the air flow generated by the flow generator 8, so that the air flow moves along the conical hood body 7a and is gradually gathered and compressed to increase the pressure of the air flow, and then the air flow with a certain pressure is stably transported to the aerosol channel 5a2 through the tube body 7b and the air inlet 5e1, and then the drug aerosol is delivered to the patient's mouth, nose and throat through the air flow, so that the patient is actively medicated and precise drug administration is achieved.

[0052] Furthermore, the flow generator 8 and the air collecting hood 7 are sealed and connected to each other, which can prevent the air flow generated by the flow generator 8 from leaking therebetween, so that the air collecting hood 7 can fully receive the air flow generated by the flow generator 8, thereby ensuring the stability of air flow delivery; preferably, the flow generator 8 is a quantitative fan, which can be set by the user to generate a set amount of air flow, thereby ensuring the accuracy of drug delivery; in this embodiment, the air volume of the flow generator 8 is 1.0 to 50 ml / s.

[0053] The Chinese medicine bomb assembly 5 of the utility model is configured to output a set amount of medicine aerosol in a controlled manner, thereby improving the effect of medicine treatment through active and precise atomization and precise delivery of medicine. Specifically, the drug cartridge assembly 5 includes a drug cartridge case 5a, an atomizer 5d and a sealing base 5e, the drug cartridge case 5a and the sealing base 5e jointly define a drug storage chamber, the top of the drug cartridge case 5a extends upward to form a mist outlet nozzle 5a1, the mist outlet nozzle 5a1 defines the air outlet, the air inlet 5e1 is formed on the sealing base 5e, and the air outlet end of the wind collecting cover 7 is in sealing contact with the sealing base 5e; the area between the air inlet 5e1 and the air outlet in the drug storage chamber forms the aerosol channel 5a2, so that the air flow can flow directly along the aerosol channel 5a2, reducing the path of the air flow and improving the drug administration efficiency. Preferably, the atomizer 5d is positioned in the drug cartridge case 5a and located in the aerosol channel 5a2, and can directly atomize the drug into an aerosol in the aerosol channel 5a2. When the air flow flows into the aerosol channel 5a2, the drug aerosol can be directly sent out from the mist outlet nozzle 5a1.

[0054] The drug is loaded into the drug storage bin in solid or liquid form. In this embodiment, the drug is mixed with solid excipients to form a solid preparation (only applicable to heating atomization) or dissolved in a solvent to form an atomizable drug solution, and then filled into the drug storage bin, or a drug solution holding portion 5b is installed in the drug storage bin, such as a cotton core, porous ceramics, adsorbents and other liquid-absorbing porous materials. In order to prevent the drug solution from becoming ineffective for a long time, the drug and the atomization solvent can be packaged separately, and the isolation film can be removed when in use to dissolve the drug into the atomization solvent, thereby extending the service life of the drug.

[0055] like Figure 2-10As shown, in the present embodiment, there are two mist outlets 5a1, one on each side, which cooperate with the nostrils respectively. Therefore, the aerosol precision delivery device in this embodiment mainly delivers drugs through the nose, induces the central nervous system through the nasal mucosa and the nasal olfactory bulb, and treats diseases related to emotional and mental aspects. The delivery device of the utility model can actively deliver drugs according to the needs of users, solving the problem that some users are unable to actively inhale appropriate doses of drugs and control the deposition site of drugs due to insufficient breathing strength. The aerosol precision delivery device in this embodiment achieves accurate and timely treatment of users or self-help of users through active targeted drug delivery (antidote is actively administered through the nasal cavity and respiratory tract). The awakening of anesthetized patients after surgery can usually only be achieved by injecting drugs; or when an emergency attack of type I allergic reaction causes breathing difficulties, patients usually implement self-help by injecting spare drugs. The aerosol precision delivery device in this embodiment can completely replace injection drug delivery through active nasal cavity and respiratory tract administration. The outlet diameter D of the mist outlet nozzle 5a1 is 1.0mm≤D≤3.5mm. The mist outlet nozzle 5a1 within this diameter range can achieve a balance between the amount of mist and the speed of mist outlet, avoiding the problem of trapped air caused by the mist outlet nozzle 5a1 being too small. When the mist outlet nozzle 5a1 is larger, the force of the mist outlet is insufficient and it is impossible to effectively administer the drug to the user. At the same time, the above-mentioned diameter setting can also ensure that the mist outlet nozzle 5a1 fits the nasal cavity, thereby improving the comfort of use. Specifically, the diameter D of the mist outlet nozzle 5a1 is 2.5mm, and can also be any value in the range of 1.0mm≤D≤3.5mm. The inner side of the mist outlet nozzle 5a1 is configured to be able to gather the cone of the aerosol, so as to fit the nostrils, prevent leakage, and improve the delivery accuracy of the aerosol. It should be noted that the above-mentioned trapped air refers to the fact that the aerosol cannot flow out effectively because the outlet flow rate is less than the aerosol output flow rate, and it seems to be trapped in the aerosol channel 5a2, which reduces the delivery accuracy.

[0056] It should be noted that the atomizer 5d in the utility model is a heating atomizer device or an ultrasonic atomizer device. For drugs with excellent thermal stability, the solid drug preparation can be directly heated or prepared into a liquid atomizer and then heated to evaporate and atomize into an aerosol. Since some drugs are unstable at high temperatures and easily decompose and become ineffective, ultrasonic atomizer devices are more advantageous than heating atomizer devices for thermally unstable drugs. The heating atomizer device is a heating element (solid atomizer), a ceramic core or a cotton core heating atomizer 5d (liquid atomizer). Similar heating atomization methods have been widely used in the electronic cigarette industry; the ultrasonic atomizer device is a piezoelectric ceramic atomizer 5d or a mesh atomizer 5d. Ultrasonic atomization is also a conventional atomization method, which is widely used in the medical and beauty industries, and its specific structure will not be described in detail.

[0057] Furthermore, a drug cartridge sleeve 6 is provided, and the drug cartridge assembly 5 is detachably attached to the drug cartridge sleeve 6; a positioning hole 6a is provided at the bottom of the drug cartridge sleeve 6, and the positioning hole 6a is connected to the air inlet 5e1. The positioning hole 6a is suitable for limiting the position of the wind collecting hood 7. During assembly, the air outlet end of the wind collecting hood 7 can pass through the positioning hole 6a and then connect to the air inlet 5e1.

[0058] Since the atomizer 5d is arranged in the drug cartridge 5a, in order to supply electric energy to the atomizer 5d, an electrode portion 5f for transmitting electric energy to the atomizer 5d is embedded in the sealing base 5e. Figure 6-7 As shown, specifically, there are two electrode parts 5f, which are metal parts embedded in the sealing base 5e, or other objects that can conduct electricity. The bottom of the drug cartridge sleeve 6 has a conductive connector 6b electrically connected to the control device. The conductive connector 6b has two conductive connectors 6b connected to the electrode parts 5f in a one-to-one correspondence. When the drug cartridge assembly 5 is assembled in the drug cartridge sleeve 6, the electrode parts 5f in its base are in contact with the conductive connector 6b to achieve circuit communication, so that the operation of the drug cartridge assembly 5 can be controlled by the control device to generate a set dose of drug aerosol. In order to ensure the electrical coupling effect between the conductive connector 6b and the electrode part 5f, the conductive connector 6b in this embodiment adopts an elastic conductive connector 6b. When the drug cartridge assembly 5 is installed in the drug cartridge sleeve 6, the conductive connector 6b can always be electrically coupled with the electrode part 5f.

[0059] Furthermore, if Figure 4-5 As shown, the cartridge case 6 has at least one positioning column 11, and the flow generator 8 and the wind collecting hood 7 are both fixedly connected to the positioning column 11; the positioning column 11 extends toward the side close to the flow generator 8. In the present embodiment, four positioning columns 11 are provided, which are respectively located around the flow generator 8. The wind collecting hood 7 and the cartridge case 6 are supported by the positioning columns 11, so that the connection between the cartridge case 6 and the wind collecting hood 7 is more stable, and at the same time, it is ensured that the air outlet end of the wind collecting hood 7 can be sealed and connected with the air inlet 5e1 to ensure the stability of air flow transportation.

[0060] like Figure 1-11 As shown, the utility model also provides a drug aerosol delivery device, including a shell 2, a drug cartridge assembly 5 and an air supply system, wherein the air supply system is the above-mentioned air supply system, wherein the size and shape of the shell 2 are configured to be holdable in the user's hand, and the size is compact, making it convenient for the user to carry; the delivery device also includes the above-mentioned control device, which is used to receive user instructions, and can not only drive the flow generator 8 to generate a set amount of air flow, but also drive the drug cartridge assembly 5 to output a set amount of drug aerosol. By mixing the set amount of air flow and the set amount of drug aerosol, precise drug administration can be achieved to improve the treatment effect.

[0061] In order to achieve precise drug delivery, the drug cartridge assembly 5 of the utility model is configured to be able to controllably output atomized particles with a particle size range of 20nm to 20μm. Aerosols of different particle sizes will be deposited in the corresponding respiratory tract to implement targeted drug delivery of part or all of the respiratory tract. The respiratory tract is divided into upper and lower parts: the nose, pharynx, and larynx are collectively referred to as the upper respiratory tract. The trachea, bronchi, and lung organs are collectively referred to as the lower respiratory tract, or the tracheal tree. After research by the utility model inventor, atomized particles of different particle sizes are deposited in different positions in the respiratory tract. As long as the particle size of the atomized particles is controlled, the drug can be administered to different respiratory tract positions, thereby achieving precise drug delivery. For heating cotton core atomizers, the size of the atomized particles can be adjusted by controlling the viscosity of the atomizer, the power of the heating element, and the size of the airflow. For ceramic core atomizers, the size of the atomized particles can be adjusted by controlling the viscosity of the atomizer, the size of the porous ceramic aperture, the power of the heating element, and the airflow velocity, but for ultrasonic atomizers, the particle size of the atomized particles must be controlled by a mesh screen to control the aerosol particle size. Fig.11 It is the distribution diagram of aerosol particles output by the drug cartridge assembly 5 measured by professional instruments. Fig.11 As shown, the bar graph in the figure represents the probability of aerosol appearing in different particle size ranges, and the wavy line represents the percentage of aerosol amount within the particle size range. It can be seen from the figure that the particle size range of the aerosolized particles generated by the atomization device in this example is generally 1 to 10 μm, and the amount of aerosol within this range is close to 100%, and is approximately normally distributed. Furthermore, the proportion of fog particles in the particle size range of 1 to 5 μm is about 60%, which not only ensures the stability of the particle size output, but also the aerosolized particles in this particle size range can be deposited in the patient's lungs, thereby achieving precise drug delivery and improving the effect of drug treatment. It should be noted that the above-mentioned professional instruments and equipment can use the PSA series laser particle size analyzer produced by Anton Paar, which uses dynamic light scattering technology for measurement. Dynamic light scattering (DLS) is a physical technology used to characterize the particle and molecular size in suspensions or solutions.

[0062] The flow generator 8 is configured to output an air flow with a controlled air volume of 1.0 to 50 ml / s; wherein, in order to configure the drug cartridge assembly 5 to be able to controllably adjust the output of the aerosol, during operation, the output of the aerosol can be adjusted by controlling the power of the atomizer 5d, the atomization time, and the air volume of the fan. The output adjustment can be program-set based on the electronic prescription issued by the doctor, or can be manually adjusted based on the actual demand for the drug by the user.

[0063] Furthermore, in order to facilitate the user to manually adjust the output of the aerosol, the control device includes a circuit board 9, on which an indicator light 3 and a button 4 are provided, and an operating part for the user to press is combined on the shell 2. In order to save space, the circuit board 9 is arranged vertically in the gap between the drug cartridge assembly 5 and the shell 2, specifically, in the gap between the shell 2 and the drug cartridge sleeve 6, and the drug cartridge sleeve 6 is pressed against the back of the circuit board 9 to support the operating part. The above configuration reduces the difficulty of installation and saves internal space, and has the effect of significantly reducing the size of the whole machine, so that the product is easy to hold in the palm of the user and is convenient for the user to operate. In addition, in order to prevent waste caused by accidental touch, for example, when the user puts the product in a pocket, a handbag or a backpack, the objects squeeze each other and easily cause accidental touch to start atomization and cause waste, and may contaminate other objects of the user, the outer surface of the operating part in this embodiment is flat or slightly lower than the outer surface of the shell 2.

[0064] like Figure 5 As shown, the housing 2 also includes a battery 10. The bottom of the housing 2 is also provided with a charging interface electrically connected to the battery 10, so that the battery 10 can be charged when the battery 10 is low on power, thereby improving the battery life of the battery 10. The bottom side wall of the housing 2 is formed with an air inlet hole 2c, and an air inlet cavity is formed between the fan and the housing 2. In order to further reduce the overall size of the product, the utility model places the battery 10 horizontally in the air inlet cavity. In order to facilitate the installation of the internal structure, the housing 2 is divided into a left housing 2a and a right housing 2b, and the top of the housing 2 has an opening. The drug cartridge sleeve 6 is clamped between the left housing 2a and the right housing 2b, and the drug cartridge assembly 5 can be slidably installed in the drug cartridge sleeve 6. Figure 3 The figure shows the internal structure after the left shell 2a is removed. Figure 4 The figure shows the internal structure after the right shell 2b is removed. The left shell 2a and the right shell 2b can be fixedly installed by fasteners, such as screws, or by snaps, and an air inlet 2c is provided on the right shell 2b. In addition, a box cover 1 is connected to the top of the shell 2, and the box cover 1 is pivotally connected to the shell 2. The box cover 1 can be closed and opened by flipping, which is convenient and hygienic to use.

[0065] The above is only a specific implementation of the utility model, but the protection scope of the utility model is not limited thereto. Any changes or substitutions that can be easily thought of by a person skilled in the art within the technical scope disclosed by the utility model should be included in the protection scope of the utility model. Therefore, the protection scope of the utility model should be based on the protection scope of the claims.

Claims

1. An air supply system for a drug aerosol delivery device, the drug aerosol delivery device comprising: A drug cartridge assembly for generating drug aerosol, wherein an aerosol passage for receiving the aerosol is defined in the drug cartridge assembly, and the aerosol passage has an air inlet and an air outlet; It is characterized in that the air supply system has: a flow generator for generating a set amount of air flow; and The air gathering hood is connected to the flow generator and the air inlet to gather the set amount of air flow and then transport it to the aerosol channel.

2. The air supply system according to claim 1, characterized in that: In the area between the flow generator and the cartridge assembly, the wind gathering cover has a portion with a gradually decreasing cross-sectional area to gather the air flow.

3. The air supply system according to claim 1 or 2, characterized in that: The air outlet end of the air collecting hood is configured to be suitable for docking with the air inlet.

4. The air supply system according to claim 3, characterized in that: The ammunition cartridge assembly comprises a sealing base, the air inlet is formed on the sealing base, and the air outlet end of the air collecting hood is in sealing contact with the sealing base.

5. The air supply system according to claim 1 or 2, characterized in that: Also available: a cartridge case, wherein the cartridge assembly is detachably attached to the cartridge case; The bottom of the cartridge case is provided with a positioning hole, and the positioning hole is suitable for defining the position of the wind gathering cover.

6. The air supply system according to claim 5, characterized in that: The air outlet end of the air collecting cover passes through the positioning hole and then connects to the air inlet.

7. The air supply system according to claim 5, characterized in that: The cartridge case is provided with at least one positioning column, and the flow generator and the wind gathering cover are both fixedly connected to the positioning column.

8. The air supply system according to claim 7, characterized in that: The positioning post extends toward a side close to the flow generator.

9. The air supply system according to claim 1, characterized in that: The flow generator and the wind collecting cover are sealedly connected.

10. The air supply system according to claim 1, characterized in that: The flow generator is a quantitative fan.

11. The air supply system according to claim 10, characterized in that: The air volume of the flow generator is 1.0-50 ml / s.

12. The air supply system according to claim 1, characterized in that: The system also includes a control device configured to drive the flow generator to generate a set amount of airflow according to an operation instruction.

13. A drug aerosol delivery device, characterized in that: It comprises a shell, a cartridge assembly and an air supply system, wherein the air supply system is the air supply system according to any one of claims 1 to 12.

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