Angle adjusting type mouse fixing device

By designing an angle-adjusting mouse fixture, using a rotation device, a height adjustment component and an angle adjustment arm, the problem that the fixed device of small and medium-sized animals in the prior art cannot adjust the position, and the rapid setting position of mice in the experiment is achieved Adjustment and fixation improve the authenticity and reliability of experimental data.

CN222426315UActive Publication Date: 2025-02-07FOURTH MILITARY MEDICAL UNIVERSITY
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Patent Information

Application Number
CN202420856403.5
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-04-23
Publication Date
2025-02-07
Estimated Expiration
2034-04-23

AI Technical Summary

Technical Problem

The existing small animal fixtures cannot achieve the positional adjustment of small animals, resulting in the breaking of the specific hemodynamic characteristics of the animals during the experiment, resulting in untrue experimental results, especially the false appearance of optical coherent tomography and intraocular pressure measurement. Negative condition.

Method used

An angle-adjusting mouse fixing device is designed, including a rotating device, a height adjustment component, an angle adjustment arm and a fixing seat. Through the cooperation of these components, the height, horizontal angle and body inclination of the mouse can be quickly adjusted to achieve small Rapid adjustment and fixation of the set position of the mouse in the experiment.

Benefits of technology

The rapid adjustment and fixation of the set position of mice in the experiment was achieved, ensuring that the hemodynamic status of the mice remained unchanged, improving the authenticity and reliability of the experimental data, and avoiding the occurrence of false negative results.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses an angle adjusting type mouse fixing device which comprises a rotating device, a height adjusting assembly, an angle adjusting arm and a fixing base. The height adjusting assembly comprises a fixed arm, an adjusting arm and a height supporting arm, the fixed arm is fixed to the top of the rotating assembly, one end of the height supporting arm is rotationally connected with one end of the fixed arm, one end of the adjusting arm is rotationally connected with the middle of the height supporting arm, and the other end of the adjusting arm is connected with the fixed arm through a sliding locking mechanism. One end of the angle supporting arm is connected with the upper end of the height supporting arm through the locking assembly, the other end of the angle supporting arm is connected with the fixing base, the fixing base is used for being connected with an animal fixing plate, and the fixing device achieves rapid adjustment of the animal body position through the rotating device, the height adjusting assembly and the angle adjusting arm.
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Description

Technical Field

[0001] The utility model relates to the technical field of animal experimental equipment, in particular to an angle-adjustable mouse fixing device. Background Art

[0002] In small animal in vivo biological function examination experiments, such as fundus photography, optical coherence tomography and vascular imaging, pupil monitoring, intraocular pressure measurement and other experiments in ophthalmology, the animals are required to always maintain the set position required by the experimental model, that is, not to change their original hemodynamic state during modeling. For example, in animal experiments simulating special conditions of space weightlessness such as hind limb unloading, whether the required inspection eye position can be accurately found according to the set position required by the experimental design, and the animal's established set position can be maintained during the functional examination. This is a key link in determining whether the experiment can collect real and accurate relevant data.

[0003] However, the current small animal fixation devices can only meet the simple fixation and cannot adjust the body position of the small animals. For example, the head of the small animal is downward and the body is tilted 45 degrees, that is, the body position is set. During the experiment, only the small animals with horizontal bodies can be monitored. The set body position of the animal experiment is changed in the horizontal state, thereby breaking its specific hemodynamic characteristics, causing the experimental results of the living animal biological function examination to fail to truly reflect its pathological changes, especially optical coherence tomography angiography and intraocular pressure measurement. Two key examination data have false negatives, which makes it difficult to carry out such biological function examination experiments smoothly, and it is impossible to accurately keep the hemodynamic changes of the small animals at all times, and observe special eye position lesions; or use different pads to support the two ends of the small animal fixation board so that the small animal reaches the set position, but it requires multiple adjustments and it is difficult to effectively fix and position the small animal fixation board. Utility Model Content

[0004] In view of the problems existing in the prior art, the utility model provides an angle-adjustable mouse fixing device, which can quickly adjust the angle of the mouse during detection and improve the implementation efficiency.

[0005] The utility model is realized by the following technical solutions:

[0006] An angle-adjustable mouse fixing device comprises a rotating device, a height-adjusting component, an angle-adjusting arm and a fixing seat;

[0007] The height adjustment assembly includes a fixed arm, an adjusting arm and a height support arm. The fixed arm is fixed on the top of the rotating assembly. One end of the height support arm is rotatably connected to one end of the fixed arm. One end of the adjusting arm is rotatably connected to the middle of the height support arm. The other end of the adjusting arm is connected to the fixed arm via a sliding locking mechanism. One end of the angle support arm is connected to the upper end of the height support arm via a locking assembly. The other end of the angle support arm is connected to a fixed seat, and the fixed seat is used to connect an animal fixing plate.

[0008] Preferably, the sliding locking mechanism comprises a locking block and a locking groove;

[0009] A rotating shaft is provided at the lower end of the adjusting arm, one end of the locking block is sleeved on the rotating shaft, and a limiting block cooperating with the locking groove is provided at the other end of the locking block. Multiple locking grooves are arranged at intervals along the length direction of the fixed arm. When the limiting block is connected to different locking grooves, the angle of the adjusting arm can be changed.

[0010] Preferably, a groove extending downward is provided on the top surface of the fixed arm, sliding grooves are provided on both sides of the groove, both ends of the rotating shaft are located in the sliding grooves, and the locking groove is located in the groove.

[0011] Preferably, a driving block is provided at the end of the locking block.

[0012] Preferably, the locking assembly includes a locking bolt and a friction plate, the ends of the angle support arm and the height support arm are rotatably connected via the locking bolt, and the friction plate is sleeved on the bolt and located between the angle support arm and the height support arm.

[0013] Preferably, a slot is provided on the fixing seat, and one end of the animal fixing plate is inserted into the slot.

[0014] Preferably, the rotating assembly includes a base and a steering wheel;

[0015] The fixed arm is arranged on the top of the steering wheel, a fixed shaft is embedded in the center of the base, and the center of the steering wheel is connected with the fixed shaft through a bearing.

[0016] Preferably, a screw is provided on the edge of the steering wheel, and the lower end of the screw abuts against the top surface of the base.

[0017] Preferably, a plug-in plate is provided at one end of the fixing plate, the plug-in plate is used to be connected to the fixing seat, and a telescopic rod is provided at the other end.

[0018] Preferably, the fixing plate is provided with two mounting grooves, the two mounting grooves are arranged in parallel and spaced apart, and a neck plate is provided at one end of the mounting groove.

[0019] Compared with the prior art, the utility model has the following beneficial technical effects:

[0020] The utility model provides an angle-adjustable mouse fixing device, wherein a rotating device is used to drive the small animal to rotate 360 ​​degrees in a horizontal plane, a height-adjusting component is used to adjust the height of the small animal, and an angle-adjusting component is used to adjust the body position of the small animal. By controlling the height, horizontal angle and body inclination angle of the small animal, rapid adjustment and fixation of the body position set during small animal experiments can be achieved; when the fixing device of the present application is used to detect the small animal, the various small animal living biological function test data obtained are more authentic and reliable. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] Figure 1 This is a schematic diagram of the structure of the mouse fixing device of the utility model;

[0022] Figure 2 It is a structural schematic diagram of the adjustment component of the utility model;

[0023] Figure 3 It is a structural schematic diagram of the fixed arm of the utility model;

[0024] Figure 4 This is a schematic diagram of the installation of the height support arm and the angle support arm of the utility model;

[0025] Figure 5 The utility model is a top view of the mouse fixing device.

[0026] In the figure: 1. base; 2. steering wheel; 3. fixed arm; 4. adjustment arm; 5. height support arm; 6. fixed seat; 7. mouse; 8. telescopic rod; 9. screw; 10. fixed shaft; 11. locking block; 12. slide groove; 13. locking groove; 14. bump; 15. neck plate; 16. mounting groove; 17. angle support arm; 18. slot; 19. fixed plate. DETAILED DESCRIPTION

[0027] The present invention will be further described in detail below in conjunction with the accompanying drawings, which are intended to explain the present invention rather than to limit it.

[0028] See also Figure 1-5 , an angle-adjustable mouse fixing device, comprising a rotating device, an adjusting component, a fixing seat 6 and a fixing plate 19.

[0029] The adjustment component includes a height adjustment component and an angle adjustment component. The height adjustment component is connected to the rotation component, the angle adjustment component is connected to the height adjustment component, the fixed seat is connected to the degree of freedom of the angle adjustment component, the fixed plate 19 is detachably connected to the fixed seat, the small animal is fixed on the fixed plate, the rotation device is used to drive the small animal to rotate 360° in the horizontal plane, the height adjustment component is used to adjust the height of the small animal, and the angle adjustment component is used to adjust the body position of the small animal. By controlling the height, horizontal angle and body inclination angle of the small animal, the rapid adjustment and fixation of the set body position during the small animal experiment can be achieved.

[0030] The height adjustment assembly includes a fixed arm 3, an adjusting arm 4 and a height support arm 5. The fixed arm 3 is fixed at the top of the rotating assembly. One end of the height support arm 5 is rotatably connected to one end of the fixed arm 3. One end of the adjusting arm 4 is rotatably connected to the middle of the height support arm 5. The other end of the adjusting arm 4 is connected to the fixed arm 3 via a sliding locking mechanism. The height of the height support arm is controlled by changing the connection position of the adjusting arm 4 and the fixed arm.

[0031] The sliding locking mechanism includes a locking block 11, a sliding groove 12 and a locking groove 13; a rotating shaft is provided at the lower end of the adjusting arm 4, one end of the locking block 11 is sleeved on the rotating shaft, and a limiting block cooperating with the locking groove is provided at the other end of the locking block, and the limiting block extends downward, and a plurality of locking grooves are arranged at intervals along the length direction of the fixed arm. When the limiting block is connected to different locking grooves, the angle of the adjusting arm 4 can be changed, and the inclination angle of the height support arm can be changed at the same time, so as to realize the height adjustment of the fixed plate.

[0032] The cross-section of the fixed arm is U-shaped, and a plurality of protrusions 14 are arranged at intervals on the inner bottom surface of the fixed arm. The plurality of protrusions are arranged at intervals along the length direction of the fixed arm, and a spatial travel locking groove 13 is formed between two protrusions, and a slide groove 12 is arranged on the two inner side walls of the fixed arm. The slide groove is arranged along the length direction of the fixed arm, and the two ends of the rotating shaft connected to the locking block are located in the slide groove. At the same time, the lower end of the adjusting arm is located in the U-shaped groove of the fixed arm, and the slide groove is located at the top of the protrusion. The fixed arm adopts a U-shaped groove structure, and the lower end of the adjusting arm 4 is located in the U-shaped groove of the adjusting arm, which plays a positioning role on both sides of the adjusting arm. At the same time, the lower end of the adjusting arm is connected to the slide groove through the rotating shaft, so as to horizontally position the adjusting arm.

[0033] Furthermore, in order to facilitate the operation of the locking block, a driving block is provided at the end of the locking block. When the driving block is pulled downward, the locking block rotates upward and separates from the locking slot, and then the adjusting arm is pushed or pulled to achieve the angle adjustment of the height support plate. A torsion spring can also be provided on the rotating shaft to apply clockwise downward pressure to the locking block through the torsion spring, thereby avoiding the problem of separation of the locking block and the locking slot due to external force.

[0034] See also Figure 4The adjustment assembly includes a locking assembly and an angle support arm 17. One end of the angle support arm 17 is connected to the upper end of the height support arm through the locking assembly, and the other end of the angle support arm 17 is connected to the fixing seat. The locking assembly is used to fix the angle support arm 17 and the height support arm.

[0035] The end of the angle support arm 17 is provided with a U-shaped groove, and the end of the height support arm is arranged in the U-shaped groove. The locking assembly includes a locking bolt and a friction plate. The angle support arm 17 and the height support arm are connected by bolts. Friction plates are respectively provided on both sides of the height support arm and are sleeved on the bolts. The angle support arm 17 and the height support arm are positioned by the locking force of the bolts. At the same time, the friction plate is used to increase the resistance so that the angle support arm 17 and the height support arm are kept in a fixed state.

[0036] A card slot 18 is provided on the fixing seat, and one end of the fixing plate is inserted into the card slot to realize the fast disassembly and assembly of the fixing plate and the fixing member 6, thereby improving the experimental efficiency. A top screw can also be provided on the side wall of the card slot. When the fixing plate is inserted into the card slot, it is positioned by the top screw to realize the fixation of the two.

[0037] In another embodiment, the fixing seat is connected to the fixing plate by a plurality of bolts.

[0038] The rotating assembly includes a base 1 and a steering wheel 2 arranged at the center thereof, a fixed arm is arranged on the top of the steering wheel, a fixed shaft is embedded in the center of the base 1, the fixed shaft is a stepped shaft, the center of the steering wheel 2 is connected to the fixed shaft through a bearing, a wave screw is arranged on the edge of the steering wheel, the lower end of the wave screw abuts against the top surface of the base to realize the positioning of the steering wheel, further, a plurality of grooves matching the wave screw are arranged on the top surface of the base, and the plurality of grooves are arranged at intervals along the rotation path of the wave screw.

[0039] See also Figure 5 The top of the fixing plate is used to fix the animal, and a plug-in plate is provided at one end thereof, which is used to connect with the fixing seat. Two mounting grooves 16 are provided on the fixing plate, and the two mounting grooves 16 are arranged in parallel and spaced apart. A neck plate 15 is provided at one end of the mounting groove for fixing the neck of the animal; taking a mouse as an example, the mouse is first fixed between the two mounting grooves, and then a restraint belt is wrapped around the body of the mouse. After the two ends of the restraint belt pass through the mounting grooves, the two ends of the restraint belt are bonded by Velcro, and two screws are provided on the fixing plate. The neck plate 15 is pressed onto the neck of the mouse, and the two ends of the neck plate are mounted on the screws by nuts.

[0040] Since one end of the fixed plate is fixedly connected to the fixed seat 6 and the other end is in a free state, in order to reduce the vibration of the fixed plate, a telescopic rod 8 is provided at the other end of the fixed plate to support the fixed plate. The telescopic rod 8 includes a sleeved outer rod and an inner rod, and the outer rod and the inner rod are connected by threads. The upper end of the outer rod is connected to the bottom of the fixed plate, and the inner rod is rotated to adjust its extended length until the lower end of the inner rod abuts against the top surface of the steering wheel.

[0041] When using the angle-adjustable mouse fixing device, the mouse is first fixed on the fixing plate 19, and then the fixing plate is connected to the fixing seat, and then the steering wheel is turned to adjust the horizontal angle of the mouse, and then the height of the mouse is adjusted by the height support rod, and finally the tilt angle of the mouse is controlled by the angle adjustment arm to keep the mouse in the set position, and then the mouse is experimented.

[0042] This angle-adjustable mouse fixture, through a variety of variable components, enables the animal to rotate 360 ​​degrees freely after being stably fixed, and has personalized variable tilt angles, etc., which solves such problems well, and has a good fixation effect. Only one experimenter is needed to adjust the experimental animal to the required position according to the corresponding experimental needs and conduct subsequent experimental operations. After comparing the traditional and the above-mentioned fixtures for inspection, the various small animal live biological function inspection data obtained by the fixture of this application are more real and reliable. This utility fills the vacancy of small animal tilt position fixators and provides good hardware support for small animal live biological function inspection experiments.

[0043] The above content is only for explaining the technical idea of ​​the utility model and cannot be used to limit the protection scope of the utility model. Any changes made on the basis of the technical solution in accordance with the technical idea proposed by the utility model shall fall within the protection scope of the claims of the utility model.

Claims

1. An angle-adjustable mouse fixing device, characterized in that: It comprises a rotating device, a height adjustment component, an angle adjustment arm and a fixing seat (6); The height adjustment assembly comprises a fixed arm (3), an adjustment arm (4) and a height support arm (5); the fixed arm (3) is fixed on the top of the rotating assembly; one end of the height support arm (5) is rotatably connected to one end of the fixed arm (3); one end of the adjustment arm (4) is rotatably connected to the middle of the height support arm (5); the other end of the adjustment arm (4) is connected to the fixed arm (3) via a sliding locking mechanism; one end of the angle support arm (17) is connected to the upper end of the height support arm via a locking assembly; the other end of the angle support arm (17) is connected to a fixed seat; and the fixed seat is used to connect an animal fixing plate.

2. The angle-adjustable mouse fixing device according to claim 1, characterized in that: The sliding locking mechanism comprises a locking block (11) and a locking groove (13); The lower end of the adjusting arm (4) is provided with a rotating shaft, one end of the locking block (11) is sleeved on the rotating shaft, and the other end of the locking block is provided with a limiting block that cooperates with the locking groove. The plurality of locking grooves are arranged at intervals along the length direction of the fixed arm. When the limiting blocks are connected to different locking grooves, the angle of the adjusting arm (4) can be changed.

3. The angle-adjustable mouse fixing device according to claim 2, characterized in that: The top surface of the fixed arm is provided with a groove extending downward, and sliding grooves are provided on both sides of the groove. The two ends of the rotating shaft are located in the sliding grooves, and the locking groove is located in the groove.

4. The angle-adjustable mouse fixing device according to claim 2, characterized in that: A driving block is arranged at the end of the locking block.

5. The angle-adjustable mouse fixing device according to claim 1, characterized in that: The locking assembly comprises a locking bolt and a friction plate. The ends of the angle support arm (17) and the height support arm are rotatably connected via the locking bolt. The friction plate is sleeved on the bolt and is located between the angle support arm (17) and the height support arm.

6. The angle-adjustable mouse fixing device according to claim 1, characterized in that: The fixing seat is provided with a card slot (18), and one end of the animal fixing plate is inserted into the card slot.

7. The angle-adjustable mouse fixing device according to claim 1, characterized in that: The rotating assembly comprises a base (1) and a steering wheel (2); The fixed arm is arranged on the top of the steering wheel, a fixed shaft is embedded in the center of the base (1), and the center of the steering wheel (2) is connected to the fixed shaft through a bearing.

8. The angle-adjustable mouse fixing device according to claim 7, characterized in that: The edge of the steering wheel is provided with a screw, and the lower end of the screw abuts against the top surface of the base.

9. The angle-adjustable mouse fixing device according to claim 1, characterized in that: One end of the fixing plate is provided with a plug-in plate, which is used to be connected with the fixing seat, and the other end is provided with a telescopic rod.

10. The angle-adjustable mouse fixing device according to claim 1, characterized in that: The fixing plate is provided with two mounting grooves (16), the two mounting grooves (16) are arranged in parallel and spaced apart, and a neck plate (15) is provided at one end of the mounting groove.