Vacuum suction filtration tank for biopharmacy

Abstract

The utility model discloses a vacuum suction filtration tank for biopharmacy, and relates to the technical field of biopharmacy. The device comprises a base, a suction filtration bottle is arranged at the top of the base, an output pipe is arranged on the circumferential side face of the suction filtration bottle in a communicating mode, a vacuum suction filtration machine located on one side of the suction filtration bottle is arranged at the top of the base, a rubber pipe is connected between the vacuum suction filtration machine and the output pipe, and a Buchner funnel is inserted into the top of the suction filtration bottle. And a sealing sleeve matched with the suction flask is fixedly sleeved on the peripheral side surface of the funnel pipe in the Buchner funnel. According to the Buchner funnel, through the bearing box which is arranged in a sliding manner, when a solid-liquid mixture is subjected to vacuum filtration, solids in the bearing box after filtration can be independently taken out firstly, so that the situation that the safety of operators is influenced by flying of the solids in the Buchner funnel in the process of pulling out the Buchner funnel due to the fact that a sealing sleeve on the Buchner funnel and a suction flask are clamped too tightly is avoided; and the safety and the convenience of operation are effectively improved.

Description

Technical Field

[0001] The utility model belongs to the technical field of biopharmaceuticals, in particular to a vacuum filtration tank for biopharmaceuticals. Background Art

[0002] Biopharmaceutical raw materials are primarily derived from natural biological materials, including microorganisms, human bodies, animals, plants, and marine organisms. With the advancement of biotechnology, purposefully produced biological raw materials have become the primary source of biopharmaceutical raw materials. Examples include animal raw materials produced through immunization, microorganisms produced through genetic modification, and other cell-based materials. Biopharmaceuticals are characterized by high pharmacological activity, minimal toxicity and side effects, and high nutritional value. Biopharmaceuticals primarily include proteins, nucleic acids, carbohydrates, and lipids.

[0003] In the biopharmaceutical process, the separation of solid-liquid mixtures is generally accomplished by vacuum filtration. A filtration flask, a Büchner funnel, and a vacuum filter are used in vacuum filtration. The sealing rubber pad on the Büchner funnel is clipped onto the filtration flask. After the solid-liquid mixture is separated, the clip is too tight, which can easily cause solid matter in the Büchner funnel to splash during the disassembly process, thereby affecting the safety of the operator.

[0004] To this end, we provide a biopharmaceutical vacuum filtration tank to solve the above problems. Utility Model Content

[0005] The purpose of the present utility model is to provide a vacuum filtration tank for biopharmaceuticals, which can make it possible to take out the solids in the filtration box separately when vacuum filtering a solid-liquid mixture through a sliding carrier box, so as to avoid the sealing sleeve on the Büchner funnel being too tightly connected to the filtration bottle, causing the solids therein to fly during the process of pulling out the Büchner funnel, thereby affecting the safety of the operator, effectively improving the safety and convenience of operation, and solving the problem that the sealing rubber pad on the existing Büchner funnel is clamped on the filtration bottle, and after the solid-liquid mixture is separated, the solids in the Büchner funnel are easily splashed during the process of disassembling the Büchner funnel due to the too tight clamping, thereby affecting the safety of the operator.

[0006] In order to solve the above technical problems, the present invention is achieved through the following technical solutions:

[0007] The utility model discloses a vacuum filtration tank for biopharmaceuticals, comprising a base; a filtration bottle is provided on the top of the base, an output pipe is provided on the peripheral side surface of the filtration bottle, a vacuum filter is provided on the top of the base and is located on one side of the filtration bottle, a rubber tube is connected between the vacuum filter and the output pipe, a Büchner funnel is inserted into the top of the filtration bottle, a sealing sleeve matching the filtration bottle is provided on the peripheral side surface of the funnel in the Büchner funnel, a carrying box is slidably connected to the inner wall of the Büchner funnel, a plurality of leakage holes are provided on the inner bottom of the carrying box, and a U-shaped plate is fixedly connected to the top of the carrying box.

[0008] The utility model is further configured such that the outer peripheral side of the carrying box is symmetrically fixedly connected with a slider which is slidably connected with the inner peripheral side of the Buchner funnel, and the inner peripheral side of the Buchner funnel is symmetrically provided with sliding grooves which match the two sliders.

[0009] The present invention is further configured such that a vertical plate is fixedly connected to the top of the base, and a clamping assembly is provided on the vertical plate.

[0010] The utility model is further configured such that the clamping assembly includes a rectangular frame slidably sleeved on the vertical plate, an outer side surface of the rectangular frame is symmetrically hingedly connected to an arc-shaped clamping plate matching the suction filtration bottle, and a spring is fixedly connected between the two opposite side surfaces of the two arc-shaped clamping plates.

[0011] The utility model is further configured such that two opposite side surfaces of the two arc-shaped splints are fixedly connected with anti-slip pads, and the top ends of the two arc-shaped splints are fixedly connected with shifting rods.

[0012] The utility model is further configured such that a hand-tightening bolt is threadedly connected between the rectangular frame and the vertical plate, a through hole matching the hand-tightening bolt is penetrated through one side surface of the rectangular frame, and a plurality of threaded holes matching the hand-tightening bolt are opened on one side surface of the vertical plate.

[0013] The utility model is further configured such that a plurality of foot pads are evenly and fixedly connected to the bottom of the base.

[0014] The utility model has the following beneficial effects:

[0015] 1. The utility model adopts a sliding supporting box, so that when vacuum filtering a solid-liquid mixture, the solid in the supporting box after filtration can be taken out separately, so as to avoid the sealing sleeve on the Büchner funnel being too tightly connected with the suction bottle, which would cause the solid matter in the Büchner funnel to fly out during the process of pulling out, thereby affecting the safety of the operator, and effectively improving the safety and convenience of operation.

[0016] 2. The utility model adjusts the height of the rectangular frame and the arc-shaped clamping plate upward or downward so that the clamping assembly can better clamp the suction bottle. Then, the arc-shaped clamping plate is opened by the lever, and the suction bottle is placed between the two arc-shaped clamping plates. The lever is released, and the arc-shaped clamping plate is driven to move toward the outer wall of the suction bottle under the elastic force of the spring, thereby completing the fixation of the suction bottle and improving the stability of the suction bottle. Finally, the arc-shaped plate is fixed by hand-tightening the bolts.

[0017] Of course, any product implementing the present invention does not necessarily need to achieve all of the advantages described above at the same time. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the following briefly introduces the drawings required for describing the embodiments. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without creative work.

[0019] Figure 1 This is a schematic diagram of the three-dimensional structure of a vacuum filtration tank for biopharmaceuticals.

[0020] Figure 2 This is a schematic diagram of the side view of the three-dimensional structure of a vacuum filtration tank for biopharmaceuticals.

[0021] Figure 3 This is a schematic diagram of the three-dimensional structure of the connection between the Buchner funnel and the chute in a vacuum filtration tank for biopharmaceuticals.

[0022] Figure 4 The figure is a schematic diagram of the three-dimensional structure of the connection between the carrier box, the slider and the U-shaped plate in a vacuum filtration tank for biopharmaceuticals.

[0023] Figure 5 This is a schematic diagram of the three-dimensional structure of a clamping component in a vacuum filtration tank for biopharmaceuticals.

[0024] In the accompanying drawings, the components represented by the reference numerals are as follows:

[0025] 1-base, 2-filtration bottle, 3-output pipe, 4-vacuum filter, 5-rubber tube, 6-Buchner funnel, 7-bucket tube, 8-sealing sleeve, 9-carrying box, 10-slider, 11-slide, 12-leak hole, 13-U-shaped plate, 14-vertical plate, 15-rectangular frame, 16-arc-shaped splint, 17-spring, 18-lever, 19-through hole, 20-hand-tightening bolt, 21-threaded hole, 22-foot pad, 23-clamping assembly. DETAILED DESCRIPTION

[0026] The following will be combined with the accompanying drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the embodiments described are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention. Specific embodiment 1

[0028] See also Figure 1-5 The utility model is a vacuum filtration tank for biopharmaceuticals, comprising a base 1; a suction bottle 2 is provided on the top of the base 1, and an output pipe 3 is provided on the peripheral side of the suction bottle 2; a vacuum filter 4 is provided on the top of the base 1 on one side of the suction bottle 2, and a rubber tube 5 is connected between the vacuum filter 4 and the output pipe 3. A Buchner funnel 6 is inserted into the top of the suction bottle 2, and a fixed sleeve on the outer peripheral side of the bucket tube 7 in the Buchner funnel 6 is provided with a sealing sleeve 8 matching the suction bottle 2; the inner wall of the Buchner funnel 6 is slidably connected to a carrying box 9, and the outer peripheral side of the carrying box 9 is symmetrically fixedly connected with a slider 10 slidably connected to the inner peripheral side of the Buchner funnel 6. The inner peripheral side of the Buchner funnel 6 is symmetrically provided with a slide groove 11 matching the two sliders 10, and a plurality of leakage holes 12 are opened on the inner bottom of the carrying box 9. A U-shaped plate 13 is fixedly connected to the top of the carrying box 9, and a plurality of foot pads 22 are evenly fixedly connected to the bottom of the base 1.

[0029] The operating process of this embodiment is: through the sliding support box 9, when vacuum filtering the solid-liquid mixture, the solids in the support box 9 after filtration can be taken out separately, so as to avoid the sealing sleeve 8 on the Büchner funnel 6 and the suction bottle 2 being too tightly connected, causing the solids in the Büchner funnel 6 to fly out during the process of pulling out, thereby affecting the safety of the operator, and effectively improving the safety and convenience of the operation. Specific embodiment 2

[0031] See also Figure 1-5 On the basis of the first specific embodiment, the top of the base 1 is fixedly connected to a vertical plate 14, and a clamping assembly 23 is provided on the vertical plate 14. The clamping assembly 23 includes a rectangular frame 15 slidably sleeved on the vertical plate 14, and an outer side surface of the rectangular frame 15 is symmetrically hingedly connected to an arc-shaped clamping plate 16 that matches the suction filtration bottle 2. A spring 17 is fixedly connected between the opposite sides of the two arc-shaped clamping plates 16, and the opposite sides of the two arc-shaped clamping plates 16 are fixedly connected to anti-slip pads, and the tops of the two arc-shaped clamping plates 16 are fixedly connected to a lever 18.

[0032] The operation process of this embodiment is as follows: by adjusting the height of the rectangular frame 15 and the arc-shaped clamping plate 16 upward or downward, the clamping assembly 23 can better clamp the suction bottle 2, then the arc-shaped clamping plate 16 is opened by the lever 18, and the suction bottle 2 is placed between the two arc-shaped clamping plates 16, and the lever 18 is released. Under the elastic force of the spring 17, the arc-shaped clamping plate 16 is driven to move toward the outer wall of the suction bottle 2, thereby completing the fixation of the suction bottle 2 and improving the stability of the suction bottle 2. Finally, the arc-shaped plate 16 is fixed by hand-tightening the bolt 20. Specific embodiment three

[0034] See also Figure 1-5 On the basis of the first and second specific embodiments, a hand-tightening bolt 20 is threadedly connected between the rectangular frame 15 and the vertical plate 14. A through hole 19 matching the hand-tightening bolt 20 is opened through one side of the rectangular frame 15, and a plurality of threaded holes 21 matching the hand-tightening bolt 20 are opened on one side of the vertical plate 14.

[0035] The operation process of this embodiment is as follows: by using the hand-tightening bolt 20 in conjunction with the threaded hole 21 , the arc-shaped clamping plate 16 can be fixed more conveniently and quickly after the height adjustment is completed.

[0036] Throughout this specification, references to terms such as "one embodiment," "example," or "specific example" indicate that a specific feature, structure, material, or characteristic described in conjunction with that embodiment or example is included in at least one embodiment or example of the present invention. In this specification, schematic representations of these terms do not necessarily refer to the same embodiment or example. Furthermore, the specific features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.

[0037] The preferred embodiments of the present invention disclosed above are intended only to help illustrate the present invention. The preferred embodiments do not describe all details in detail, nor do they limit the present invention to the specific embodiments described. Obviously, many modifications and variations are possible based on the contents of this specification. These embodiments are selected and described in detail in this specification to better explain the principles and practical applications of the present invention, thereby enabling those skilled in the art to better understand and utilize the present invention. The present invention is limited only by the claims and their full scope and equivalents.

Claims

1. A vacuum filtration tank for biopharmaceuticals, comprising a base (1); characterized in that: A suction filtration bottle (2) is arranged on the top of the base (1), and an output pipe (3) is arranged on the peripheral side of the suction filtration bottle (2). A vacuum filter (4) located on one side of the suction filtration bottle (2) is arranged on the top of the base (1), and a rubber tube (5) is connected between the vacuum filter (4) and the output pipe (3). A Büchner funnel (6) is inserted on the top of the suction filtration bottle (2), and a sealing sleeve (8) matching the suction filtration bottle (2) is fixedly sleeved on the outer peripheral side of the funnel (7) in the Büchner funnel (6). A supporting box (9) is slidably connected to the inner wall of the Büchner funnel (6), and a plurality of leakage holes (12) are opened on the inner bottom of the supporting box (9). A U-shaped plate (13) is fixedly connected to the top of the supporting box (9).

2. A biopharmaceutical vacuum filtration tank according to claim 1, characterized in that: The outer peripheral side surface of the carrier box (9) is symmetrically fixedly connected with a slider (10) which is slidably connected to the inner peripheral side surface of the Buchner funnel (6), and the inner peripheral side surface of the Buchner funnel (6) is symmetrically provided with a slide groove (11) matching the two sliders (10).

3. A biopharmaceutical vacuum filtration tank according to claim 2, characterized in that: The top of the base (1) is fixedly connected to a vertical plate (14), and a clamping assembly (23) is provided on the vertical plate (14).

4. A biopharmaceutical vacuum filtration tank according to claim 3, characterized in that: The clamping assembly (23) comprises a rectangular frame (15) slidably mounted on a vertical plate (14); an outer side surface of the rectangular frame (15) is symmetrically hingedly connected to an arc-shaped clamping plate (16) matching the suction filtration bottle (2); and a spring (17) is fixedly connected between two opposite side surfaces of the two arc-shaped clamping plates (16).

5. A biopharmaceutical vacuum filtration tank according to claim 4, characterized in that: The two opposite side surfaces of the two arc-shaped clamping plates (16) are fixedly connected with anti-slip pads, and the top ends of the two arc-shaped clamping plates (16) are fixedly connected with shifting rods (18).

6. A biopharmaceutical vacuum filtration tank according to claim 5, characterized in that: A hand-tightening bolt (20) is threadedly connected between the rectangular frame (15) and the vertical plate (14); a through hole (19) matching the hand-tightening bolt (20) is formed through one side surface of the rectangular frame (15); and a plurality of threaded holes (21) matching the hand-tightening bolt (20) are formed on one side surface of the vertical plate (14).

7. A biopharmaceutical vacuum filtration tank according to claim 6, characterized in that: A plurality of foot pads (22) are evenly and fixedly connected to the bottom of the base (1).

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