Sampling device of liquid chromatogram

Abstract

The utility model relates to the technical field of liquid chromatographs, in particular to a liquid chromatogram sampling device which comprises a base, supporting legs are fixedly mounted at four corners of the top of the base, a top seat is fixedly mounted at the tops of the supporting legs, and a sample storage mechanism is fixedly mounted at the top of the top seat. By twisting the adjusting handle and pushing the guide block to rotate, the adjusting plate moves outwards, then the adjusting frame and the connecting shaft are pushed to move outwards, the limiting block is contracted, the limiting frame is separated, and the injector can be pulled out, meanwhile, the elastic clamping frame can stably clamp the piston rod, dismounting is convenient, and during mounting, a new injector is inserted into the limiting frame, the adjusting handle is loosened, and the piston rod can be pulled out. The limiting spring is reset, the limiting block is pushed to move inwards, the injector is clamped and positioned, then the top of the piston rod is clamped through the elastic clamping frame, and installation is completed, so that the operation process is simplified, the use convenience is improved, the injector can be rapidly replaced, and the device operation is further simplified.

Description

Technical Field

[0001] The present application relates to the technical field of liquid chromatography, and in particular to a liquid chromatography injection device. Background Art

[0002] The injection device of liquid chromatography is mainly an injector, whose function is to accurately deliver the sample solution into the chromatographic column. At present, the manual injector needs to be manually operated. A certain amount of sample solution is sucked with a syringe and injected into the injection system of the liquid chromatograph. Although this method is simple to operate, the liquid chromatograph usually needs to select samples, extract samples and inject samples when performing injection. It uses multiple rotatable samples to perform autonomous sampling, and uses an electric slide rail that moves up and down to accurately extract samples. Finally, an electric push rod is used to push the sample into the chromatograph for detection, thereby realizing the automation of injection and improving the efficiency of the chromatograph.

[0003] Through searching, Chinese patent announcement number CN208568697U discloses an automatic sample injection device for high performance liquid chromatograph, which includes a base, a fixed base and a suction mechanism, wherein the fixed base is arranged on the base, and the suction mechanism is connected to the fixed base through a sampling support frame, and the base is provided with a sample loading platform at a position corresponding to the suction mechanism; the suction mechanism includes a mounting vertical plate, a sliding guide rail, a driving screw and an injection assembly, the sliding guide rail and the driving screw are both vertically arranged on the sampling support frame, the mounting vertical plate is slidably arranged in the sliding guide rail, the injection assembly is arranged on one side of the mounting vertical plate, the driving screw is arranged on the other side of the mounting vertical plate and is fixedly connected to the mounting vertical plate, and the driving screw drives the mounting vertical plate to move up and down in the sliding guide rail; the sample loading platform is rotatably connected to the base, and a plurality of clamping grooves for placing sample bottles are arranged on the sample loading platform, and the clamping grooves are arranged in a ring and are arranged opposite to the injection assembly.

[0004] With respect to the above-mentioned related technologies, the utility model inventor found the following defects:

[0005] Although the above-mentioned device can have the functions of automatic sampling and selective sampling during use, it still has certain defects in its specific application process. First of all, during its use, the syringe is fixedly installed on the device, and the syringe needs to be cleaned or replaced each time the sample is injected. Obviously, the above-mentioned device cannot replace and clean the syringe, which shows that it has certain defects and shortcomings. At the same time, it only has a single set of syringes. When performing multiple sets of sampling tests, using a single set of syringes for injection and sampling, it is obviously easy to cause sample contamination, thereby affecting its normal detection accuracy. Therefore, it is necessary to improve the existing equipment. Utility Model Content

[0006] In order to improve the overall operational convenience of the device, the present application provides a liquid chromatography injection device.

[0007] The present application provides a liquid chromatography sample injection device, which adopts the following technical scheme: comprising a base, support legs are fixedly installed at the four corners of the top of the base, a top seat is fixedly installed on the top of the support legs, a sample storage mechanism is fixedly installed on the top of the top seat, a support frame is fixedly installed on the top rear side of the top seat, a telescopic cylinder is fixedly installed on the front end of the support frame, a first motor is fixedly installed on the bottom output end of the telescopic cylinder passing through the support frame, a fixed block is fixedly installed on the bottom output end of the first motor, a sampling mechanism is fixedly installed at equal intervals on the outside of the fixed block, and a sample injection tube is fixedly installed on the middle part of the rear side of the top seat;

[0008] The sampling mechanism includes side rails, which are fixedly installed on the outside of the fixed block at equal intervals, a displacement component is movably installed inside the side rails, a clamping component is fixedly installed on the lower end of the outer side of the side rails, and a syringe is installed on the lower end of the side rails through the clamping component.

[0009] Optionally, the displacement assembly includes a second motor, which is fixedly mounted on the top of the side rail, and a screw is fixedly mounted on the bottom output end of the second motor passing through the side rail, and the screw is rotatably connected to the inside of the side rail, and a sliding block is threadedly connected to the outer surface of the screw, and an elastic clip frame is fixedly mounted on the outer side of the sliding block, and a clip frame is fixedly mounted on the outer end of the elastic clip frame, and the upper end of the piston rod of the syringe is clipped to the inside of the clip frame.

[0010] Optionally, the clamping assembly includes a fixed frame, which is fixedly installed on the lower end of the side rail, and limit springs are fixedly installed at both ends of the fixed frame, and limit blocks are fixedly installed on the ends of the limit springs. A limit frame is fixedly installed on the outer side of the limit block, and the syringe is inserted between the inner sides of the limit frames.

[0011] Optionally, a connecting shaft is fixedly installed on the outer end of the limit block, and an adjusting frame is fixedly installed on the outer end of the connecting shaft through the fixing frame.

[0012] Optionally, an adjustment plate is fixedly mounted on the outer end of the adjustment frame, and a guide block is rotatably connected to the bottom of the side rail.

[0013] Optionally, an adjustment handle is fixedly mounted on the bottom of the guide block, the guide block is oval in shape when viewed from above, and the outer side of the guide block and the inner side of the adjustment plate are fitted and connected.

[0014] Optionally, the sample storage mechanism includes a third motor, which is fixedly mounted at the bottom front end of the top seat, and the output end of the third motor passes through the top seat and is fixedly mounted with a turntable, and a limiting assembly is fixedly mounted at equal intervals on the top of the turntable, and a sample dish is mounted on the top of the turntable through the limiting assembly.

[0015] Optionally, the limiting assembly includes a fixed frame, which is arranged in a ring shape with equal intervals and fixedly installed on the outer side of the turntable, and telescopic springs are fixedly installed on both ends of the inner side of the fixed frame, and a movable block is fixedly installed on the inner end of the telescopic spring. The movable block is slidably connected to the interior of the fixed frame, and a clamping seat is fixedly installed on the inner end of the movable block, and the sample dish is inserted in the middle part of the fixed frame and is located between the inner sides of the clamping seats.

[0016] Optionally, the top of the turntable is provided with accommodating grooves at equal intervals, and the bottom of the sample dish is inserted into the accommodating grooves.

[0017] Optionally, the inner side of the clamping seat is V-shaped when viewed from above, and the bottom of the turntable is rotatably connected with balls arranged in a ring at equal intervals, and the bottom of the balls is fit-connected to the top of the top seat.

[0018] In summary, this application includes the following beneficial technical effects:

[0019] 1. By setting up a sample storage mechanism, the device can achieve flexible adaptation to sample dishes of different sizes. By utilizing the elastic force of the telescopic spring, the movable block slides on the inside of the fixed frame to effectively clamp and fix the sample dish. At the same time, by driving the turntable to rotate through the third motor, the position of the sample dish can be flexibly adjusted to meet the injection requirements. During the injection process, the first motor can drive the fixed block to rotate and adjust the position of the syringe to avoid cross infection and improve the detection accuracy. In addition, the telescopic spring elastic clamping design is adopted to facilitate and quickly replace the sample dish, thereby improving the ease of use of the device. Overall, this design not only improves the adaptability and injection convenience of the device, but also optimizes the operation process and improves work efficiency.

[0020] 2. By setting up the sampling mechanism, the device realizes the automatic sampling function. When the sample dish is moved to the bottom of the syringe, the telescopic cylinder pushes the syringe downward and the needle is inserted into the sample dish. Subsequently, the second motor drives the screw to rotate, causing the sliding block to slide in the side rail, pulling the piston rod upward, and extracting the sample. Next, the first motor drives the fixed block to rotate, and the syringe moves to the sampling tube. Finally, the second motor drives the screw in the opposite direction, pushing the sliding block downward, pressing the piston rod downward, and pushing the sample into the sampling tube. The whole process does not require manual intervention, which improves the sampling efficiency and accuracy, realizes the automatic operation of the device, and simplifies the experimental process.

[0021] 3. By setting up the clamping assembly, the device realizes the rapid disassembly, assembly and replacement of the syringe. The adjusting handle is twisted to push the guide block to rotate, so that the adjusting plate moves outward, and then the adjusting frame and the connecting shaft are pushed outward, the limit block shrinks, the limit frame is separated, and the syringe can be drawn out. At the same time, the elastic clamping frame can stably clamp the piston rod for easy disassembly. When installing, insert the new syringe into the limit frame, loosen the adjusting handle, the limit spring is reset, and the limit block is pushed inward to clamp and position the syringe. Then the top of the piston rod is clamped by the elastic clamping frame to complete the installation. This design simplifies the operation process, improves the ease of use, can quickly replace the syringe, and further simplifies the operation of the device. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] Figure 1 It is a schematic diagram of the overall structure in the embodiment of the present application;

[0023] Figure 2 is a schematic diagram of a top view of the structure in an embodiment of the present application;

[0024] Figure 3 is a schematic diagram of the structure viewed from above in an embodiment of the present application;

[0025] Figure 4 is a schematic diagram of the structure of the rear view in the embodiment of the present application;

[0026] Figure 5 It is a schematic diagram of the overall structure of the sample storage mechanism in the embodiment of the present application;

[0027] Figure 6 is a schematic diagram of the structure of the sample storage mechanism in the embodiment of the present application when viewed from above;

[0028] Figure 7 It is a schematic diagram of the structure of the sampling mechanism in the embodiment of the present application;

[0029] Figure 8 In the embodiment of this application Figure 7 A schematic diagram of the enlarged structure at point A;

[0030] Fig. 9 It is a schematic diagram of the bottom-up structure of the sampling mechanism in the middle figure of the embodiment of the present application.

[0031] Figure numerals: 1, base; 2, support leg; 3, top seat; 4, support frame; 5, telescopic cylinder; 6, sample storage mechanism; 61, third motor; 62, turntable; 63, limit assembly; 631, fixed frame; 632, telescopic spring; 633, movable block; 634, clamping seat; 635, receiving groove; 636, ball bearing; 64, sample dish; 7, first motor; 8, fixed block; 9, sampling mechanism; 91, side rail ; 92. Displacement assembly; 921. Second motor; 922. Screw rod; 923. Sliding block; 924. Elastic card mounting frame; 925. Card frame; 93. Clamping assembly; 931. Fixed frame; 932. Limit spring; 933. Limit block; 934. Limit frame; 935. Connecting shaft; 936. Adjustment frame; 937. Adjustment plate; 938. Guide block; 939. Adjustment handle; 94. Syringe; 10. Sample injection tube. DETAILED DESCRIPTION

[0032] The following is combined with Figure 1-9 This application is described in further detail.

[0033] The present application discloses a liquid chromatography sample injection device. Figure 1 As shown, it includes a base 1, support legs 2 are fixedly installed at the four corners of the top of the base 1, a top seat 3 is fixedly installed on the top of the support legs 2, a sample storage mechanism 6 is fixedly installed on the top of the top seat 3, a support frame 4 is fixedly installed on the top rear side of the top seat 3, a telescopic cylinder 5 is fixedly installed on the front end of the support frame 4, a first motor 7 is fixedly installed on the bottom output end of the telescopic cylinder 5 passing through the support frame 4, a fixing block 8 is fixedly installed on the bottom output end of the first motor 7, a sampling mechanism 9 is fixedly installed at equal intervals on the outer side of the fixing block 8, and a sample injection tube 10 is fixedly installed in the middle of the rear side of the top seat 3;

[0034] The sampling mechanism 9 includes a side rail 91, which is fixedly installed on the outer side of the fixed block 8 at equal intervals. A displacement component 92 is movably installed inside the side rail 91. A clamping component 93 is fixedly installed on the lower end of the outer side of the side rail 91. A syringe 94 is installed on the lower end of the side rail 91 through the clamping component 93. A telescopic cylinder 5 is installed at the front end of the support frame 4 for accurately controlling the lifting and lowering of the syringe 94. The bottom of the telescopic cylinder 5 is connected to the first motor 7. The first motor 7 drives the sampling mechanisms 9 arranged at equal intervals on the outer side to move through the fixed block 8. These sampling mechanisms 9 are the core parts of the sampling device and are responsible for the extraction and injection operations of the sample. In addition, a sampling tube 10 is also arranged in the middle of the rear side of the top seat 3 for use In order to send the extracted samples into the liquid chromatography system, the design of the sampling mechanism 9 is particularly critical, which includes a side rail 91, a displacement assembly 92 and a clamping assembly 93. The side rail 91 is fixedly installed on the outside of the fixed block 8, and the displacement assembly 92 moves inside the side rail 91 to accurately control the displacement of the syringe 94 between the sample dish 64 and the injection tube 10. The clamping assembly 93 is responsible for stably clamping the syringe 94 to ensure stability and accuracy during the sampling process. The sampling device can realize automatic extraction and injection of samples, improve the efficiency and accuracy of the experiment, and at the same time, the design of the sampling mechanism 9 makes the replacement of the syringe 94 simple and quick, further improving the ease of use and flexibility of the device.

[0035] Please refer to Fig. 9The displacement assembly 92 includes a second motor 921, which is fixedly mounted on the top of the side rail 91. A screw rod 922 is fixedly mounted on the bottom output end of the second motor 921, which passes through the side rail 91. The screw rod 922 is rotatably connected to the inside of the side rail 91. A sliding block 923 is threadedly connected to the outer surface of the screw rod 922. An elastic card-mounting frame 924 is fixedly mounted on the outer side of the sliding block 923. A card-mounting frame 925 is fixedly mounted on the outer end of the elastic card-mounting frame 924. The upper end of the piston rod of the syringe 94 is card-connected to the inside of the card-mounting frame 925. The second The motor 921 is fixedly installed on the top of the side rail 91, and serves as a driving source to provide power for the entire displacement assembly 92. When the second motor 921 is started, its bottom output end drives the screw rod 922 to rotate. The screw rod 922 is rotatably connected to the inside of the side rail 91, ensuring the stability and accuracy of the screw rod 922 during the rotation process. The outer surface of the screw rod 922 is threadedly connected with a sliding block 923. This design enables the sliding block 923 to slide up and down along the screw rod 922 when the screw rod 922 rotates. The outer surface of the sliding block 923 is connected to the inner surface of the screw rod 922. The side of the elastic card frame 924 is fixedly installed. The elastic card frame 924 has a certain elasticity and recovery, can be deformed when subjected to force, and can return to its original state after release. The outer end of the elastic card frame 924 is fixedly installed with a card frame 925. The card frame 925 is used to fix the piston rod of the syringe 94. During the sampling process, when the syringe 94 needs to be moved, the second motor 921 is started, driving the screw rod 922 to rotate, and then driving the sliding block 923 to slide on the screw rod 922. The movement of the sliding block 923 will drive the elastic card frame The frame 924 and the card frame 925 move together to realize the displacement of the syringe 94. Due to the design of the elastic card frame 924 and the card frame 925, the piston rod of the syringe 94 can be stably clamped in the card frame 925 to ensure that it will not fall off or shake during the movement. The design of this displacement assembly 92 not only realizes the precise movement of the syringe 94, but also ensures the stability and reliability during the sampling process. At the same time, due to the use of motor drive and threaded transmission, the operation of the entire displacement assembly 92 is simpler and more efficient.

[0036] Please refer to Fig. 9The clamping assembly 93 includes a fixed frame 931, which is fixedly mounted on the lower end of the side rail 91. The two ends of the fixed frame 931 are fixedly mounted with limit springs 932. The ends of the limit springs 932 are fixedly mounted with limit blocks 933. The outer side of the limit block 933 is fixedly mounted with a limit frame 934. The syringe 94 is inserted between the inner sides of the limit frames 934. The fixed frame 931, as the basic structure of the clamping assembly 93, is firmly mounted on the lower end of the side rail 91 to provide a stable support for the entire assembly. The limit springs 932 are fixedly installed at both ends of the fixed frame 931. The limit springs 932 have a certain elasticity and restoring force, and can be deformed when subjected to external force, and return to the original state after the external force disappears. The end of the limit spring 932 is fixedly installed with a limit block 933. The limit block 933 is closely connected with the limit spring 932 to form an elastic clamping mechanism. When the syringe 94 needs to be fixed, the limit block 933 can be moved to the limit under the action of the limit spring 932. The limit frame 934 plays a guiding and positioning role, ensuring that the syringe 94 can be accurately inserted between the inner sides of the limit frame 934. This design not only ensures the stability of the syringe 94, but also makes the installation and removal of the syringe 94 more convenient and quick. When the syringe 94 needs to be installed on the clamping assembly 93, it is only necessary to insert the syringe 94 between the inner sides of the limit frame 934, and then adjust the structure of the clamping assembly 93 so that the limit block 933 clamps the outer side of the syringe 94 under the action of the limit spring 932. In this way, the syringe 94 is firmly fixed on the clamping assembly 93, and the sampling operation can be started. The clamping assembly 93 realizes the stable clamping and positioning of the syringe 94 through the coordinated action of the fixed frame 931, the limit spring 932, the limit block 933 and the limit frame 934, thereby improving the sampling accuracy and operation reliability of the sampling device.

[0037] Please refer to Fig. 9The outer end of the adjustment frame 936 is fixedly installed with an adjustment plate 937, and the bottom of the side rail 91 is rotatably connected with a guide block 938. The outer end of the adjustment frame 936 is fixedly installed with an adjustment plate 937. The existence of the adjustment plate 937 provides the operator with more control points and force application points, so that they can operate more conveniently when they need to adjust the position or clamping force of the syringe 94. Specifically, when the operator wants to adjust the clamping state or position of the syringe 94, the operator can apply appropriate force or rotate the adjustment plate 937, and then through the action of the adjustment frame 936 and the connecting shaft 935, the limit block 933 and the clamping force can be accurately controlled. In addition, the bottom of the side rail 91 is rotatably connected with a guide block 938. The design of the guide block 938 is to ensure that the adjustment frame 936 And the stability and accuracy of the adjustment plate 937 during movement. When the adjustment plate 937 is subjected to external force, the guide block 938 can guide it to move along a predetermined trajectory to prevent it from deviating from the track or producing unnecessary shaking. This not only helps to improve the structural stability of the entire clamping assembly 93, but also ensures the position accuracy and operational reliability of the syringe 94 during the sampling process. The design of the adjustment plate 937 and the guide block 938 plays a vital role in the clamping assembly 93 of the injection device. They together constitute a stable and adjustable clamping system, which provides strong support for the stable clamping and precise control of the syringe 94. At the same time, this also reflects the refinement and humanization of the design of the injection device, aiming to improve the efficiency and accuracy of experimental operations.

[0038] Please refer to Figure 8The outer end of the limit block 933 is fixedly installed with a connecting shaft 935, and the outer end of the connecting shaft 935 passes through the fixed frame 931 and is fixedly installed with an adjusting frame 936. The connecting shaft 935 is a key component connecting the limit block 933 and the adjusting frame 936. Its outer end passes through the fixed frame 931 and is fixedly installed with the adjusting frame 936. The setting of the adjusting frame 936 allows the operator to adjust the position and clamping force of the limit block 933 through the adjusting frame 936 when it is necessary to disassemble or replace the syringe 94. Specifically, when it is necessary to release the syringe 94, the adjusting frame 936 can be operated to make the connecting shaft 935 drive the limit block 933 to move outward, thereby loosening the clamping of the syringe 94; conversely, when it is necessary When clamping the syringe 94, the limit block 933 can be moved inward through the adjustment frame 936 to increase the clamping force of the syringe 94. This design not only makes the installation and disassembly of the syringe 94 more convenient and quick, but also improves the adaptability and flexibility of the clamping assembly 93, and can adapt to syringes 94 of different specifications and sizes. In addition, through the cooperation of the connecting shaft 935 and the adjustment frame 936, the clamping force can be accurately adjusted to ensure the stability and accuracy of the syringe 94 during the sampling process. Therefore, the application of the connecting shaft 935 and the adjustment frame 936 not only optimizes the structural design of the clamping assembly 93, but also improves the ease of use and operating accuracy of the entire injection device.

[0039] Please refer to Figure 7, an adjustment handle 939 is fixedly installed at the bottom of the guide block 938, and the guide block 938 has an elliptical shape when viewed from above. The outer side of the guide block 938 and the inner side of the adjustment plate 937 are fitted and connected. When it is necessary to adjust the clamping state or position of the syringe 94, the operator can rotate the adjustment handle 939 to make the guide block 938 rotate at the bottom of the side rail 91, and then adjust the clamping force through a series of linkage mechanisms. In addition, the guide block 938 is designed to have an elliptical shape when viewed from above. This design is not only beautiful, but more importantly, it helps to increase the stability of the contact surface between the guide block 938 and the side rail 91, making it more stable during rotation and less prone to shaking. At the same time, the elliptical shape can also reduce the friction resistance of the guide block 938 during rotation to a certain extent, making the operation smoother. Moreover, the guide block The outer side of 938 and the inner side of the adjustment plate 937 are tightly fitted and connected. This design ensures the stability and accuracy of the adjustment plate 937 during movement. When the adjustment plate 937 is subjected to external force, due to its tight fit with the guide block 938, it can ensure that the adjustment plate 937 moves along the shape of the guide block 938 to prevent it from deviating from the predetermined trajectory. This connection method not only improves the overall structural stability of the clamping assembly 93, but also makes the position adjustment of the syringe 94 more accurate and reliable. The design of the guide block 938 fully considers the convenience, stability and accuracy of operation. Through the design elements such as the adjustment handle 939, the elliptical upward-looking shape and the tight fit connection with the adjustment plate 937, the precise control of the clamping state of the syringe 94 is achieved, thereby improving the practical performance and operating experience of the injection device.

[0040] Please refer to Figure 6The limiting assembly 63 includes a fixing frame 631, which is arranged in a ring at equal intervals and fixedly installed on the outer side of the turntable 62. Both ends of the inner side of the fixing frame 631 are fixedly installed with telescopic springs 632. The inner end of the telescopic spring 632 is fixedly installed with a movable block 633. The movable block 633 is slidably connected to the inside of the fixing frame 631. The inner end of the movable block 633 is fixedly installed with a clamping seat 634. The sample dish 64 is inserted into the middle part of the fixing frame 631 and is located between the inner sides of the clamping seat 634. The fixing frame 631, as the basic structure of the limiting assembly 63, is arranged in a ring at equal intervals and fixedly installed on the outer side of the turntable 62. This design not only ensures the uniformity of the distribution of the fixing frame 631, but also enables the turntable 62 to rotate smoothly, reducing the shaking caused by uneven force. The inner ends of the fixing frame 631 are fixedly installed with telescopic springs 632. The telescopic springs 632 have a certain elasticity and restoring force. When subjected to external force, the telescopic springs 632 can be deformed and quickly return to their original state after the external force disappears. This feature enables the limit assembly 63 to be adaptively adjusted according to the size and shape of the sample dish 64, ensuring the stability and reliability of the clamping. The inner end of the telescopic spring 632 is fixedly installed with a movable block 63 3. The movable block 633 is slidably connected to the inside of the fixed frame 631. This design allows the movable block 633 to slide inside the fixed frame 631, so as to adjust the position of the clamping seat 634 according to actual needs. When the sample dish 64 needs to be placed, the sample dish 64 only needs to be inserted into the middle part of the fixed frame 631 and placed between the inner sides of the clamping seat 634. At this time, the telescopic spring 632 will be squeezed by the sample dish 64 and deformed, driving the movable block 633 and the clamping seat 634 to move inward, so as to tightly clamp the sample dish 64. The clamping seat 634 is a component that directly contacts the sample dish 64, and its design is also fully Taking stability and compatibility into consideration, the inner shape and size of the clamping seat 634 match the sample dish 64, which can ensure that the sample dish 64 will not shake or slip during the clamping process. At the same time, the clamping seat 634 is made of soft material to reduce wear and contamination of the sample dish 64. The limiting component 63 achieves stable clamping and adaptive adjustment of the sample dish 64 through the coordinated action of the fixed frame 631, the telescopic spring 632, the movable block 633 and the clamping seat 634. This design not only improves the reliability and safety of sample storage, but also simplifies the process of sample replacement and operation, thereby improving the efficiency and convenience of experimental work.

[0041] Please refer to Figure 5The sample storage mechanism 6 includes a third motor 61, which is fixedly mounted on the bottom front end of the top seat 3. The output end of the third motor 61 passes through the top seat 3 and is fixedly mounted with a turntable 62. A limiting assembly 63 is fixedly mounted on the top of the turntable 62 at equal intervals. A sample dish 64 is mounted on the top of the turntable 62 through the limiting assembly 63. The sample storage mechanism 6 is mainly composed of the third motor 61, the turntable 62 and the limiting assembly 63. The third motor 61 is fixedly mounted on the bottom front end of the top seat 3 as the power source of the entire storage mechanism. The output end of the third motor 61 passes through the top seat 3 and is fixedly mounted with a turntable 62. The turntable 62 is a key component for storing the sample dish 64. The limiting assembly 63 is fixedly mounted on the top of the turntable 62 at equal intervals. These limiting assemblies 63 play a role in fixing and positioning the sample dish 64. Through the limiting assembly 63, the sample dish 64 can be stably placed on the turntable 62 to prevent displacement or tipping during rotation or sampling. , the third motor 61 drives the turntable 62 to rotate, so that the sample dish 64 to be sampled rotates to the sampling position. At this time, the sampling mechanism 9 of the sampling device, such as the syringe 94 mentioned above, will move to the top of the sample dish 64 under the precise control system, and push the syringe 94 downward through the telescopic cylinder 5, so that the needle of the syringe 94 is inserted into the sample dish 64, thereby completing the sampling operation. This design not only improves the accuracy and efficiency of sampling, but also greatly reduces the error and inconvenience of human operation. At the same time, through the coordinated use of the turntable 62 and the limit assembly 63, continuous storage and sampling of multiple sample dishes 64 can be achieved, further improving the continuity and automation of the experimental work. The sample storage mechanism 6 is an important component of the liquid chromatography sampling device. It realizes stable storage and efficient sampling of samples through the coordinated work of the third motor 61, the turntable 62 and the limit assembly 63, providing a reliable sample source for subsequent chromatographic analysis.

[0042] Please refer to Figure 5The top of the turntable 62 is provided with receiving grooves 635 at even intervals, and the bottom of the sample dish 64 is inserted into the inside of the receiving grooves 635. The receiving grooves 635 are carefully designed according to the size and shape of the sample dish 64 to ensure that the sample dish 64 can be tightly inserted into the inside of the receiving grooves 635. When the sample dish 64 is placed on the turntable 62, its bottom will naturally insert into the corresponding receiving grooves 635 to form a stable supporting structure. The advantage of this design is that it can not only prevent the sample dish 64 from shifting or tipping over during the rotation of the turntable 62, but also reduce the sample The friction between the sample dish 64 and the turntable 62 is reduced, thereby extending the service life. At the same time, the opening of the receiving groove 635 makes the placement of the sample dish 64 more neat and beautiful, improving the visualization and operability of the entire sample storage mechanism 6. In addition, since the receiving grooves 635 are opened at equal intervals, this also ensures that the position of each sample dish 64 on the turntable 62 is evenly distributed, avoiding the problem of uneven force or unbalanced rotation due to uneven position. This uniform distribution not only helps to improve the accuracy of the sampling process, but also helps to improve the stability and reliability of the entire sampling device.

[0043] Please refer to Figure 5 The inner side of the clamping seat 634 is V-shaped when viewed from above. The bottom of the turntable 62 is rotatably connected with balls 636 arranged in a ring at equal intervals. The bottom of the balls 636 is fitted and connected to the top of the top seat 3. Firstly, the V-shaped design enables the clamping seat 634 to generate an inward clamping force when it is squeezed by the sample dish 64. This clamping force can be evenly distributed on the bottom of the sample dish 64, ensuring that the sample dish 64 will not shake or tilt during rotation or sampling. Secondly, the V-shaped clamping seat 634 can better adapt to sample dishes 64 of different sizes. Since the V-shaped opening has a certain width range, This can accommodate the bottoms of sample dishes 64 of different diameters. This design increases the compatibility and flexibility of the clamping seat 634, so that the sample storage mechanism 6 can be suitable for sample dishes 64 of various specifications. In addition, the bottom of the turntable 62 is equidistantly arranged in a ring and rotatably connected with balls 636. These balls 636 not only reduce the friction between the turntable 62 and the top seat 3, making the turntable 62 rotate more smoothly, but also play a role in supporting and stabilizing the turntable 62. The bottom of the ball 636 is fitted and connected to the top of the top seat 3 to form a stable support structure, ensuring the stability and balance of the turntable 62 when rotating at high speed.

[0044] The implementation principle of the liquid chromatography sampling device of the embodiment of the present application is as follows: by setting the sample storage mechanism 6, the sample dish 64 can be placed inside the receiving groove 635 on the top of the turntable 62 during use of the device. At this time, the movable block 633 can be pushed to slide on the inner side of the fixed frame 631 by resetting the telescopic spring 632. The elastic force of the telescopic spring 632 acts on the movable block 633 and the teeth of the fixed frame 631 to assist in clamping and fixing the sample dish 64. It can be seen that during use, the device can flexibly adapt to sample dishes 64 of different sizes according to needs, which can improve the overall use adaptability of the device. At the same time, during use, the third motor 61 can be started to operate, and the operation of the third motor 61 can assist in driving the turntable 62 to rotate. The rotation of the turntable 62 can drive the cyclic displacement of each culture dish on the top of the turntable 62, which can flexibly adjust different sample The sample dish 64 is located at the bottom of the syringe 94, and the sample dish 64 can be flexibly adjusted according to needs. When it needs to be sampled again after the sampling is completed, the first motor 7 can be started to run, and the fixed block 8 can be driven to rotate by the first motor 7. The movable displacement of each syringe 94 outside the fixed block 8 can be adjusted by rotating the fixed block 8. Different syringes 94 can be selected for use according to needs, which can avoid the situation of using a common syringe 94 for sampling, and can improve the overall sampling convenience of the device. At the same time, it can also avoid the situation of cross-infection of samples, and maximize the overall detection accuracy. When the sample dish 64 needs to be replaced, since it uses the telescopic spring 632 to resist the movable block 633 to drive the clamping seat 634 to perform elastic clamping, it is only necessary to pull out the sample dish 64 at this time, which is convenient for the device to quickly replace the sample dish 64, and can improve the overall convenience of use of the device.

[0045] By setting the sampling mechanism 9, during the sampling process of the device, when the sample dish 64 moves to the injection needle at the bottom of the syringe 94, the telescopic cylinder 5 can be started to push the syringe 94 to move downward, and the needle of the syringe 94 is inserted into the sample dish 64. At this time, the second motor 921 is started to operate, and the second motor 921 drives the screw rod 922 to rotate. The rotation of the screw rod 922 can drive the sliding block 923 to slide inside the displacement side rail 91. When the sliding block 923 slides upward, it can assist in pulling the piston rod to move upward, and the syringe 94 The sample can be drawn into the syringe 94 by moving the piston rod upward. At this time, starting the first motor 7 can drive the fixed block 8 to rotate. The rotation of the fixed block 8 can drive the syringe 94 to move to the injection tube 10. By starting the second motor 921 to reversely drive the screw rod 922 to rotate, the sliding block 923 can be pushed to drive the elastic clamping frame 924 and the clamping frame 925 to move downward. At this time, the piston rod can be pushed downward. The piston rod moves downward to push the absorbed solution into the injection tube 10 outside the syringe 94, so that the device as a whole can automatically inject samples.

[0046] By setting the clamping assembly 93, when the syringe 94 inside the clamping assembly 93 needs to be disassembled during use of the device, the adjusting handle 939 can be twisted. The adjusting handle 939 can be rotated to push the guide block 938 actively. When the guide block 938 rotates, the two ends of the guide block 938 can contact the adjusting plate 937 to move outward. The adjusting plate 937 can move outward to push the adjusting frame 936 to push the outside of the connecting shaft 935. The outside of the connecting shaft 935 can pull the limit block 933 to contact the limit spring 932 to shrink. The movement of the limit block 933 can cause the limit frame 934 to separate. At this time, the syringe 94 can be drawn out from the inside of the limit frame 934. When the syringe 94 is drawn out, the elastic card frame 924 will be toggled. The elastic card frame 924 is made of spring steel. 24 can stably clamp the top of the piston rod of the syringe 94. At this time, the piston rod of the syringe 94 can be removed by pushing the elastic clamping frame 924 to change its shape. At this time, the entire syringe 94 can be removed, and then a new syringe 94 can be taken out, and the syringe 94 is inserted between the inner sides of the limiting frame 934, and the adjusting handle 939 is loosened. The limiting spring 932 is reset to push the limiting block 933 to move inward, and the limiting block 933 pushes the limiting frame 934 to move inward to assist in clamping and positioning the syringe 94. When the syringe 94 is clamped, the top of the piston rod can be clamped by elastic clamping, so that the syringe 94 can be installed, so that the syringe 94 as a whole is easy to quickly disassemble and replace, which can improve the overall ease of use of the device, facilitate the quick replacement of the setting of the syringe 94, and further simplify the operation of the device.

[0047] The above are all preferred embodiments of the present application, and the protection scope of the present application is not limited thereto. Therefore, any equivalent changes made according to the structure, shape, and principle of the present application should be included in the protection scope of the present application.

Claims

1. A liquid chromatography sample injection device, comprising a base (1), characterized in that: Support legs (2) are fixedly mounted at the four corners of the top of the base (1); a top seat (3) is fixedly mounted on the top of the support legs (2); a sample storage mechanism (6) is fixedly mounted on the top of the top seat (3); a support frame (4) is fixedly mounted on the rear side of the top of the top seat (3); a telescopic cylinder (5) is fixedly mounted on the front end of the support frame (4); a first motor (7) is fixedly mounted on the bottom output end of the telescopic cylinder (5) passing through the support frame (4); a fixed block (8) is fixedly mounted on the bottom output end of the first motor (7); a sampling mechanism (9) is fixedly mounted at equal intervals on the outer side of the fixed block (8); and a sample injection tube (10) is fixedly mounted on the middle part of the rear side of the top seat (3); The sampling mechanism (9) comprises a side rail (91), the side rail (91) is fixedly installed at equal intervals on the outside of the fixed block (8), a displacement assembly (92) is movably installed inside the side rail (91), a clamping assembly (93) is fixedly installed at the lower end of the outer side of the side rail (91), and a syringe (94) is installed at the lower end of the side rail (91) through the clamping assembly (93); The displacement assembly (92) comprises a second motor (921), the second motor (921) is fixedly mounted on the top of the side rail (91), a screw rod (922) is fixedly mounted on the bottom output end of the second motor (921) passing through the side rail (91), the screw rod (922) is rotatably connected to the inside of the side rail (91), a sliding block (923) is threadedly connected to the outer surface of the screw rod (922), an elastic clamping frame (924) is fixedly mounted on the outer side of the sliding block (923), a clamping frame (925) is fixedly mounted on the outer end of the elastic clamping frame (924), and the upper end of the piston rod of the syringe (94) is clamped to the inside of the clamping frame (925); The sample storage mechanism (6) comprises a third motor (61), and the third motor (61) is fixedly mounted at the bottom front end of the top seat (3). The output end of the third motor (61) passes through the top seat (3) and is fixedly mounted with a turntable (62). A limit assembly (63) is fixedly mounted at equal intervals on the top of the turntable (62), and a sample dish (64) is mounted on the top of the turntable (62) via the limit assembly (63).

2. A liquid chromatography sample injection device according to claim 1, characterized in that: The clamping assembly (93) comprises a fixing frame (931), wherein the fixing frame (931) is fixedly mounted on the lower end of the side rail (91), and limit springs (932) are fixedly mounted on both ends of the fixing frame (931), and a limit block (933) is fixedly mounted on the end of the limit spring (932), and a limit frame (934) is fixedly mounted on the outer side of the limit block (933), and the syringe (94) is inserted between the inner sides of the limit frame (934).

3. A liquid chromatography sample injection device according to claim 2, characterized in that: A connecting shaft (935) is fixedly mounted on the outer end of the limit block (933), and an adjusting frame (936) is fixedly mounted on the outer end of the connecting shaft (935) through the fixing frame (931).

4. A liquid chromatography sample injection device according to claim 3, characterized in that: An adjustment plate (937) is fixedly mounted on the outer end of the adjustment frame (936), and a guide block (938) is rotatably connected to the bottom of the side rail (91).

5. A liquid chromatography sample injection device according to claim 4, characterized in that: An adjustment handle (939) is fixedly mounted on the bottom of the guide block (938). The guide block (938) is oval in shape when viewed from above. The outer side of the guide block (938) and the inner side of the adjustment plate (937) are closely connected.

6. A liquid chromatography sample injection device according to claim 1, characterized in that: The limiting assembly (63) comprises a fixing frame (631), the fixing frame (631) is arranged in a ring shape at equal intervals and fixedly mounted on the outer side of the rotating disk (62), telescopic springs (632) are fixedly mounted on both ends of the inner side of the fixing frame (631), a movable block (633) is fixedly mounted on the inner end of the telescopic spring (632), the movable block (633) is slidably connected to the inside of the fixing frame (631), a clamping seat (634) is fixedly mounted on the inner end of the movable block (633), and the sample dish (64) is inserted into the middle part of the fixing frame (631) and is located between the inner sides of the clamping seat (634).

7. A liquid chromatography sample injection device according to claim 6, characterized in that: The top of the rotating disk (62) is provided with receiving grooves (635) at even intervals, and the bottom of the sample dish (64) is inserted into the receiving grooves (635).

8. A liquid chromatography sample injection device according to claim 7, characterized in that: The inner side of the clamping seat (634) is V-shaped when viewed from above, and the bottom of the turntable (62) is rotatably connected to balls (636) arranged in a ring at equal intervals, and the bottom of the balls (636) is fitted and connected to the top of the top seat (3).

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