Traditional Chinese medicine compound active ingredient microencapsulation supercritical fluid auxiliary preparation device

Abstract

The utility model discloses a traditional Chinese medicine compound active ingredient microencapsulation supercritical fluid auxiliary preparation device which comprises a heat preservation box, a sealing door is hinged to the front face of the heat preservation box, a feeding connecting piece is fixedly connected to the top of the heat preservation box, and sliding strips are symmetrically and fixedly connected to the front face of the heat preservation box. The device can be connected with a discharge port of supercritical fluid preparation equipment through the cooperation of the heat preservation box, the sealing door and the feeding connecting piece, and then the collection beaker can be conveniently conveyed to the position below the feeding connecting piece through the cooperation of the sliding strip, the sliding plate, the embedding opening and the collection beaker. And then through cooperation of a communication port, a heating channel, an electric heater, an air inlet fan, a pressure release valve and a temperature and pressure detector, the temperature and pressure in the heat preservation box can be adjusted during material collection, so that the quality of the collected supercritical fluid can be guaranteed, the labor cost can be saved, the production efficiency can be improved, and workers can use the device conveniently.

Description

Technical Field

[0001] The utility model relates to the technical field of supercritical fluids, in particular to a supercritical fluid-assisted preparation device for microencapsulating active ingredients of a traditional Chinese medicine compound. Background Art

[0002] A fluid (gas or liquid) is called a supercritical fluid when its temperature and pressure exceed its corresponding critical point values. Compared with conventional solvents, the advantage of supercritical fluids is that their density is close to that of liquids and their viscosity is close to that of gases (low viscosity). They have the characteristics of high solubility for solutes, gas-like properties, easy diffusion, and high mass transfer efficiency. The extraction has the characteristics of both distillation and liquid-liquid extraction. The operating parameters are easy to control, and the solvent can be recycled. It is especially suitable for the separation of heat-sensitive substances in traditional Chinese medicines and can achieve the characteristic of no solvent residue. The basic principles of supercritical fluid extraction and its advantages in the extraction of effective ingredients in traditional Chinese medicines, as well as the extraction of effective ingredients in traditional Chinese medicines and the removal of impurities from Chinese herbal medicines.

[0003] At present, when the microencapsulation of the active ingredients of the traditional Chinese medicine compound is subjected to supercritical fluid extraction, the existing supercritical fluid extraction device may be used, such as a carbon dioxide supercritical extraction device for Ganoderma lucidum spore oil disclosed in Chinese Patent Application No. 202320317586.9, which discloses a carbon dioxide supercritical extraction device for Ganoderma lucidum spore oil, including a tank body, a base fixedly installed at the bottom of the tank body, a lifting mechanism provided between the base and the inside of the tank body, a connecting plate fixedly installed on the side wall of the tank body, a tank cover rotatably connected on the connecting plate, the bottom of the tank cover is tightly against the top of the tank body, a locking device is provided between the tank body and the tank cover, a filtering mechanism is provided in the tank body, an extrusion mechanism is provided on the tank cover, the bottom of the extrusion mechanism is against the top of the lifting mechanism, and a feeding mechanism is provided on the side wall of the tank body. The patent is reasonably designed, and it can squeeze out the Ganoderma lucidum spore oil in the carbon dioxide fluid remaining in the broken wall Ganoderma lucidum spores after extracting the Ganoderma lucidum spore oil, thereby reducing the waste of Ganoderma lucidum spore oil.

[0004] Although the above patent can squeeze out the Ganoderma lucidum spore oil in the carbon dioxide fluid remaining in the broken Ganoderma lucidum spores after extracting the Ganoderma lucidum spore oil, thereby reducing the waste of Ganoderma lucidum spore oil, in actual use, the patent lacks a collection structure for the extract, and the traditional collection method is mostly to pour it directly into a beaker or test tube without temperature and pressure control. Supercritical fluids have many unique properties, such as low viscosity, density, diffusion coefficient and solvation capacity, which are very sensitive to changes in temperature and pressure. When the temperature or pressure in the area changes during collection, it is very easy to cause quality impact on the collection of supercritical fluids, so that it is often necessary for a dedicated person to record and monitor it in real time, resulting in a significant increase in labor costs. The accuracy and timeliness of human observation are also lower than those of monitoring instruments.

[0005] Therefore, it is necessary to modify the material receiving device of the above patent to effectively prevent the material receiving area from being subjected to temperature and pressure control treatment, so that when the temperature or pressure of the area changes during material receiving, it is very easy to cause quality impact on the collected supercritical fluid, and the need for special personnel to supervise, resulting in a significant increase in labor costs. Utility Model Content

[0006] In order to solve the problems raised in the above-mentioned background technology, the purpose of the utility model is to provide a supercritical fluid-assisted preparation device for microencapsulation of active ingredients in traditional Chinese medicine compound, which has the advantages of being able to control the temperature and pressure of the material receiving area, saving labor costs and improving production efficiency, and being convenient for staff to use. It solves the problem that the material receiving area cannot be temperature-controlled and pressure-controlled, so that when the temperature or pressure of the area changes during material collection, it is very easy to cause the collection of supercritical fluids to be easily affected, and the need for special personnel to guard, resulting in a significant increase in labor costs.

[0007] To achieve the above-mentioned purpose, the utility model provides the following technical scheme: a supercritical fluid-assisted preparation device for microencapsulation of active ingredients in traditional Chinese medicine compound, comprising an incubator, a sealing door hinged on the front of the incubator, a feed connector fixedly connected to the top of the incubator, a slide bar symmetrically fixedly connected to the front of the incubator, a slide plate slidably connected to the inside of the slide bar, an embedding port opened on the top of the slide plate, a collecting beaker is arranged inside the embedding port, and the collecting beaker is located directly below the feed connector, a connecting port is opened on the top of the back of the incubator, a heating channel is connected to the outside of the connecting port, an electric heater is arranged inside the heating channel, an inlet fan is connected to the bottom of the heating channel, and the inlet fan is fixedly connected to the incubator, a pressure relief valve is connected to the bottom of the back of the incubator, and a temperature and pressure detector is fixedly connected to the top of the inner wall of the incubator.

[0008] As a preferred embodiment of the utility model, the top of the embedding port is fixedly connected to a support frame, both ends of the support frame are symmetrically fixedly connected to sliders, the inside of the slider is slidably connected to a sliding column, the end of the sliding column close to the collecting beaker is fixedly connected to an arc clamp, and the arc clamp is used in conjunction with the collecting beaker, the other end of the sliding column is fixedly connected to a pull block, the surface of the sliding column is provided with a spring, and the spring is located between the support frame and the pull block.

[0009] As a preferred embodiment of the utility model, a vent is provided on the top of the slide board, a roller group is fixedly connected to the bottom of the slide board, and the roller group is rollingly connected to the heat preservation box.

[0010] As a preferred embodiment of the utility model, the bottom of the thermal insulation box is fixedly connected to an electric telescopic rod, and the bottom of the electric telescopic rod is fixedly connected to a base.

[0011] As a preferred embodiment of the present invention, a first protection frame is fixedly connected to the top of the base, a second protection frame is fixedly connected to the bottom of the thermal insulation box, and the second protection frame is slidably connected to the first protection frame.

[0012] As a preferred embodiment of the present invention, a dustproof net is provided at the air inlet of the air inlet fan.

[0013] Compared with the prior art, the beneficial effects of the utility model are as follows:

[0014] 1. The utility model can connect the device to the discharge port of the supercritical fluid preparation equipment through the cooperation of the heat preservation box, the sealing door and the feed connector, and then facilitate the collection beaker to be transported to the bottom of the feed connector through the cooperation of the slide bar, the slide plate, the embedding port and the collection beaker, and then the temperature and pressure in the heat preservation box can be adjusted during the collection of the material through the cooperation of the connecting port, the heating channel, the electric heater, the air inlet fan, the pressure relief valve and the temperature and pressure detector, so as to ensure the quality of the collected supercritical fluid, save labor costs and improve production efficiency, and is convenient for the staff to use.

[0015] 2. The utility model can adapt to collection beakers of different specifications through the cooperation of the support frame, the slider, the slide column, the arc-shaped clamp, the pull block and the spring, and can clamp and position them to prevent them from shifting. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 It is a schematic diagram of the structure of the utility model;

[0017] Figure 2 It is a rear perspective schematic diagram of the structure of the utility model;

[0018] Figure 3 It is a three-dimensional schematic diagram of the skateboard of the utility model;

[0019] Figure 4 It is a three-dimensional schematic diagram of the skateboard of the utility model when viewed from above.

[0020] In the figure: 1. Insulation box; 2. Sealing door; 3. Feed connector; 4. Slide bar; 5. Slide plate; 6. Embedding port; 7. Collecting beaker; 8. Connecting port; 9. Heating channel; 10. Electric heater; 11. Inlet fan; 12. Pressure relief valve; 13. Temperature and pressure detector; 14. Support frame; 15. Sliding block; 16. Sliding column; 17. Arc clamp; 18. Pull block; 19. Spring; 20. Vent; 21. Roller group; 22. Electric telescopic rod; 23. Base; 24. First protective frame; 25. Second protective frame; 26. Dust net. DETAILED DESCRIPTION

[0021] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0022] like Figures 1 to 4 As shown, the utility model provides a supercritical fluid-assisted preparation device for microencapsulation of active ingredients in traditional Chinese medicine compound, comprising an incubator 1, a sealing door 2 is hinged on the front of the incubator 1, a feed connector 3 is fixedly connected to the top of the incubator 1, a slide bar 4 is symmetrically fixedly connected to the front of the incubator 1, a slide plate 5 is slidably connected to the inside of the slide bar 4, an embedding port 6 is provided on the top of the slide plate 5, a collecting beaker 7 is arranged inside the embedding port 6, and the collecting beaker 7 is located directly below the feed connector 3, a connecting port 8 is provided on the top of the back of the incubator 1, a heating channel 9 is connected to the outside of the connecting port 8, an electric heater 10 is arranged inside the heating channel 9, an inlet fan 11 is connected to the bottom of the heating channel 9, and the inlet fan 11 is fixedly connected to the incubator 1, a pressure relief valve 12 is connected to the bottom of the back of the incubator 1, and a temperature and pressure detector 13 is fixedly connected to the top of the inner wall of the incubator 1.

[0023] refer to Figure 3 A support frame 14 is fixedly connected to the top of the embedding port 6, and sliders 15 are symmetrically fixedly connected to the two ends of the support frame 14. A sliding column 16 is slidably connected inside the sliding column 15. An arc-shaped clamp 17 is fixedly connected to one end of the sliding column 16 close to the collecting beaker 7, and the arc-shaped clamp 17 is used in conjunction with the collecting beaker 7. A pull block 18 is fixedly connected to the other end of the sliding column 16. A spring 19 is sleeved on the surface of the sliding column 16, and the spring 19 is located between the support frame 14 and the pull block 18.

[0024] As a technical optimization solution of the utility model, through the cooperation of the support frame 14, the slider 15, the slide column 16, the arc clamp 17, the pull block 18 and the spring 19, it can adapt to collection beakers 7 of different specifications, and can clamp and position them to prevent them from shifting.

[0025] refer to Figure 4 A vent 20 is provided at the top of the slide plate 5 , a roller set 21 is fixedly connected to the bottom of the slide plate 5 , and the roller set 21 is rollingly connected to the incubator 1 .

[0026] As a technical optimization solution of the utility model, the provision of the vent 20 can ensure air circulation in the thermal insulation box 1, and the provision of the roller group 21 makes it convenient for the staff to slide the skateboard 5 and provide support force for the skateboard 5.

[0027] refer to Figure 1 The bottom of the incubator 1 is fixedly connected with an electric telescopic rod 22 , and the bottom of the electric telescopic rod 22 is fixedly connected with a base 23 .

[0028] As a technical optimization solution of the utility model, by setting the electric telescopic rod 22 and the base 23, the height of the insulation box 1 can be adjusted according to the height of the discharge port of the supercritical fluid preparation equipment, thereby improving the applicability of the device.

[0029] refer to Figure 1 and Figure 2 A first protection frame 24 is fixedly connected to the top of the base 23 , a second protection frame 25 is fixedly connected to the bottom of the heat preservation box 1 , and the second protection frame 25 is slidably connected to the first protection frame 24 .

[0030] As a technical optimization solution of the present invention, by providing the first protection frame 24 and the second protection frame 25 , the electric telescopic rod 22 can be surrounded and thus protected.

[0031] refer to Figure 2 A dustproof net 26 is provided at the air inlet of the inlet fan 11 .

[0032] As a technical optimization solution of the present invention, the dustproof net 26 is provided to achieve a dustproof effect, thereby reducing dust from entering the interior of the thermal insulation box 1 .

[0033] The working principle and use process of the utility model are as follows: when the staff uses the auxiliary preparation device to collect the supercritical fluid of the microencapsulated active ingredient of the traditional Chinese medicine compound, the device is first moved to the bottom of the discharge port of the supercritical fluid preparation equipment, and the feed connector 3 is connected to it. At this time, the height of the device can be adjusted by the electric telescopic rod 22, and then the height of the feed connector 3 can be adjusted. Then, the sealing door 2 is opened to slide out the slide plate 5, and then the pull block 18 is pulled outward to stretch the spring 19, and then the collection beaker 7 is prevented from being inserted into the embedding port 6, and then the pull block 18 is released to make the reaction force of the spring 19 bring The movable arc clamp 17 clamps the collecting beaker, then returns the slide plate 5 to its original position, and closes the sealing door 2, and then adjusts the parameters of the temperature and pressure detector 13 according to the collection conditions of the supercritical fluid, and then starts the electric heater 10, the fan inlet 11 and the pressure relief valve 12 according to the parameters of the temperature and pressure detector 13, so that the pressure and temperature in the incubator 1 can be adjusted, and then the supercritical fluid preparation equipment can be discharged, so that the supercritical fluid can fall into the collecting beaker 7 through the feed connector 3 for collection, and can ensure that the pressure and temperature of the collection environment will not change, thereby improving the collection quality.

[0034] It should be noted that, in this article, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device.

[0035] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A supercritical fluid-assisted preparation device for microencapsulation of active ingredients in a traditional Chinese medicine compound, comprising an insulated box (1), characterized in that: The front of the heat preservation box (1) is hinged with a sealing door (2), the top of the heat preservation box (1) is fixedly connected with a feed connection piece (3), the front of the heat preservation box (1) is symmetrically fixedly connected with a slide bar (4), the inside of the slide bar (4) is slidably connected with a slide plate (5), the top of the slide plate (5) is provided with an embedding opening (6), the inside of the embedding opening (6) is provided with a collection beaker (7), and the collection beaker (7) is located directly below the feed connection piece (3), and the heat preservation box (1) is provided with a sealing door (2) hinged with a sealing door (2) hinged with a feed connection piece (3), the top of the heat preservation box (1) is hinged with a sealing door (2 ... and the top of the heat preservation box (1) is hinged with a sealing door (2), A connecting port (8) is provided at the top of the back side of the box (1), the outer side of the connecting port (8) is connected to a heating channel (9), an electric heater (10) is arranged inside the heating channel (9), the bottom of the heating channel (9) is connected to an inlet fan (11), and the inlet fan (11) is fixedly connected to the heat preservation box (1), the bottom of the back side of the heat preservation box (1) is connected to a pressure relief valve (12), and the top of the inner wall of the heat preservation box (1) is fixedly connected to a temperature and pressure detector (13).

2. A supercritical fluid-assisted preparation device for microencapsulation of active ingredients in a traditional Chinese medicine compound according to claim 1, characterized in that: The top of the embedding opening (6) is fixedly connected to a support frame (14), and sliders (15) are symmetrically fixedly connected to the two ends of the support frame (14). The interior of the slider (15) is slidably connected to a slide column (16), and one end of the slide column (16) close to the collecting beaker (7) is fixedly connected to an arc-shaped clamp (17), and the arc-shaped clamp (17) is used in conjunction with the collecting beaker (7). The other end of the slide column (16) is fixedly connected to a pull block (18), and a spring (19) is sleeved on the surface of the slide column (16), and the spring (19) is located between the support frame (14) and the pull block (18).

3. The supercritical fluid-assisted preparation device for microencapsulation of active ingredients in traditional Chinese medicine compound according to claim 1, characterized in that: A vent (20) is provided at the top of the slide plate (5), a roller group (21) is fixedly connected to the bottom of the slide plate (5), and the roller group (21) is rollingly connected to the heat preservation box (1).

4. The supercritical fluid-assisted preparation device for microencapsulation of active ingredients in traditional Chinese medicine compound according to claim 1, characterized in that: The bottom of the thermal insulation box (1) is fixedly connected to an electric telescopic rod (22), and the bottom of the electric telescopic rod (22) is fixedly connected to a base (23).

5. The supercritical fluid-assisted preparation device for microencapsulation of active ingredients in traditional Chinese medicine compound according to claim 4, characterized in that: The top of the base (23) is fixedly connected to a first protection frame (24), the bottom of the thermal insulation box (1) is fixedly connected to a second protection frame (25), and the second protection frame (25) is slidably connected to the first protection frame (24).

6. The supercritical fluid-assisted preparation device for microencapsulation of active ingredients in traditional Chinese medicine compound according to claim 1, characterized in that: A dustproof net (26) is provided at the air inlet of the air inlet fan (11).

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