Production precipitation device for cytidine processing

Abstract

The utility model provides a production precipitation device for cytidine processing, which comprises a box body, a plurality of support legs are fixed at the bottom of the box body, the top of the box body is communicated with two feed pipes, valves are arranged on the feed pipes, the bottom of the box body is communicated with a blow-off pipe, two inclined plates are symmetrically arranged in the box body, and the two inclined plates are arranged on the two inclined plates. A plurality of filtering holes are formed in the inclined plates, a discharging box is arranged between the two inclined plates, a discharging rectangular pipe is arranged at the bottom of the discharging box in a communicating mode, the tops of the inclined plates are movably connected with the inner wall of the box body, a supporting seat is fixed in the box body, and a plurality of supporting springs are fixed between the supporting seat and the inclined plates; a vibration motor is arranged between the supporting seat and the inclined plate. The problem that product precipitates obtained in the existing cytidine production process cannot be quickly taken out is solved.

Description

Technical Field

[0001] The utility model relates to the field of medicine, in particular to a precipitation device for the production of cytosine nucleoside processing. Background Art

[0002] Cytosine nucleoside is an important component of RNA in humans, animals and plants. It plays an important regulatory role in the physiological and biochemical processes in organisms and has multiple physiological activities. It is mainly used as an intermediate in the production of anti-tumor and antiviral drugs. It is the main raw material for the manufacture of nucleic acid drugs such as cytarabine (Ara-CR), cyclocytidine (Cyclo C), cytidine triphosphate (CTP), uridine nucleoside (UR), and cytidine diphosphocholine (CDP-Cho li ne).

[0003] The product precipitate obtained in the existing cytosine nucleoside production process cannot be quickly removed, and the precipitate stays in the reaction solution for a long time, and is easily doped with a large number of other fixed reactant impurities, thereby affecting the product quality.

[0004] Therefore, it is necessary to provide a new precipitation device for production of cytosine nucleoside processing to solve the above technical problems. Utility Model Content

[0005] In order to solve the above technical problems, the utility model provides a precipitation device for processing cytosine nucleoside, which solves the problem that the product precipitation obtained in the production process of existing cytosine nucleoside cannot be quickly taken out.

[0006] The utility model provides a cytosine nucleoside processing and production precipitation device, comprising a box body with a plurality of supporting legs fixed at the bottom, two feed pipes are connected to the top of the box body, valves are arranged on the feed pipes, and a sewage pipe is connected to the bottom of the box body;

[0007] Two inclined plates are symmetrically arranged inside the box body, and a plurality of filter holes are opened on the inclined plates. A discharge box is arranged between the two inclined plates, and a discharge rectangular pipe is arranged at the bottom of the discharge box.

[0008] In a preferred embodiment, the top of the inclined plate is movably connected to the inner wall of the box, a support seat is fixed inside the box, a plurality of support springs are fixed between the support seat and the inclined plate, and a vibration motor is arranged between the support seat and the inclined plate.

[0009] In a preferred embodiment, a conveying auger is movably arranged inside the discharge box.

[0010] In a preferred embodiment, a first motor is installed on one side of the box body, and an output end of the first motor is connected to the central axis of the conveying auger through a coupling.

[0011] In a preferred embodiment, two closing plates are spaced apart inside the box, the closing plates are arranged through the top of the box, and the closing plates are slidably connected to the top of the box;

[0012] The bottom of the closing plate contacts the surface of the inclined plate, and a sealing gasket is arranged at the bottom of the closing plate.

[0013] In a preferred embodiment, a lifting seat is fixed between the two closing plates, a screw rod is movably provided on the top of the box body, the top of the screw rod passes through the lifting seat, and the screw rod is threadedly connected to the lifting seat;

[0014] A first bevel gear is installed on the top of the screw rod, a limit seat and a second motor are installed on the top of the box body, a rotating shaft is movably provided on the limit seat through a bearing, a second bevel gear meshing with the first bevel gear is installed on one end of the rotating shaft, and the other end of the rotating shaft is connected to the second motor through a coupling.

[0015] Beneficial effects of the utility model:

[0016] 1. When the device is used, the cytosine nucleoside mixture solution after the reaction is completed will be directly discharged into the box through the feed pipe. When the mixture solution passes through the inclined plate, the cytosine nucleoside precipitate inside the mixture solution can be filtered out through a number of filter holes. The waste liquid after filtration can be quickly discharged into the waste liquid treatment system through the sewage pipe;

[0017] 2. When the cytosine nucleoside precipitate on the inclined plate needs to be unloaded, the staff only needs to start the second motor. Under the transmission action of the first bevel gear and the second bevel gear, the screw rod will be driven to rotate. Under the action of the screw rod, the closing plate will move upward with the lifting seat. Then, the vibration motor can be started to make the precipitate on the inclined plate fall quickly into the discharge box.

[0018] Starting the first motor can drive the conveying auger to rotate. Under the action of the conveying auger, the cytosine nucleoside powder will be driven to be discharged from the discharge rectangular tube for collection. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 A three-dimensional view of the main structure of a precipitation device for cytosine nucleoside processing provided by the utility model;

[0020] Figure 2 for Figure 1 A schematic diagram of the enlarged structure of shown;

[0021] Figure 3A front view of the main structure of a precipitation device for cytosine nucleoside processing provided by the utility model;

[0022] Figure 4 The utility model provides a top view of the main structure of a precipitation device for processing and producing cytosine nucleoside.

[0023] Numbers in the figure: 1. Box body; 2. Support legs; 3. Feed pipe; 4. Valve; 5. Drain pipe; 6. Inclined plate; 7. Filter hole; 8. Discharge box; 9. Discharge rectangular tube; 10. Support seat; 11. Support spring; 12. Vibration motor; 13. Conveying auger; 14. First motor; 15. Closing plate; 16. Lifting seat; 17. Screw; 18. First bevel gear; 19. Limit seat; 20. Second motor; 21. Rotating shaft; 22. Second bevel gear. DETAILED DESCRIPTION

[0024] The utility model is further described below in conjunction with the accompanying drawings and implementation modes.

[0025] Please refer to Figure 1 , Figure 2 , Figure 3 as well as Figure 4 , Figure 1 A three-dimensional view of the main structure of the precipitation device for cytosine nucleoside processing provided by the utility model; Figure 2 for Figure 1 A schematic diagram of the enlarged structure of shown; Figure 3 A front view of the main structure of a precipitation device for cytosine nucleoside processing provided by the utility model; Figure 4 The utility model provides a top view of the main structure of the precipitation device for cytosine nucleoside processing and production.

[0026] In the specific implementation process, Figure 1-Figure 4 As shown, it includes a box body 1 with a plurality of supporting legs 2 fixed at the bottom, two feed pipes 3 are connected to the top of the box body 1, valves 4 are arranged on the feed pipes 3, and a sewage pipe 5 is connected to the bottom of the box body 1. The feed rectangular tube 3 is connected to the discharge port in the reaction container. When all the cytosine nucleoside precipitates in the reaction container are generated, the staff can quickly discharge the mixture solution inside the reaction container into the feed rectangular tube 3.

[0027] Two inclined plates 6 are symmetrically arranged inside the box body 1, and a plurality of filter holes 7 are opened on the inclined plates 6. A discharge box 8 is arranged between the two inclined plates 6. A discharge rectangular tube 9 is arranged at the bottom of the discharge box 8. A conveying auger 13 is movably arranged inside the discharge box 8. A first motor 14 is installed on one side of the box body 1. The output end of the first motor 14 is connected to the central axis of the conveying auger 13 through a coupling. Starting the first motor 14 can drive the conveying auger 13 to rotate. Under the action of the conveying auger 13, the cytosine nucleoside powder inside the discharge box 8 will be driven to be discharged from the discharge rectangular tube 9.

[0028] The top of the inclined plate 6 is movably connected to the inner wall of the box body 1, a support seat 10 is fixed inside the box body 1, a plurality of support springs 11 are fixed between the support seat 10 and the inclined plate 6, a vibration motor 12 is arranged between the support seat 10 and the inclined plate 6, and starting the vibration motor 12 can drive the inclined plate 6 to shake, so that the cytosine nucleoside precipitate located above the inclined plate 6 moves downward quickly.

[0029] Two closing plates 15 are arranged at intervals inside the box body 1. The closing plates 15 are arranged through the top of the box body 1 and are slidably connected to the top of the box body 1. The bottom of the closing plate 15 is in contact with the surface of the inclined plate 6. A sealing gasket is arranged at the bottom of the closing plate 15. The closing plate 15 can prevent other substances in the mixed solution from entering the discharge box 8.

[0030] A lifting seat 16 is fixed between the two closing plates 15, and a screw rod 17 is movably provided on the top of the box body 1. The top of the screw rod 17 passes through the lifting seat 16, and the screw rod 17 is threadedly connected to the lifting seat 16. A first bevel gear 18 is installed on the top of the screw rod 17. A limit seat 19 and a second motor 20 are installed on the top of the box body 1. A rotating shaft 21 is movably provided on the limit seat 19 through a bearing. A second bevel gear 22 meshing with the first bevel gear 18 is installed at one end of the rotating shaft 21, and the other end of the rotating shaft 21 is connected to the second motor 20 through a coupling. When it is necessary to unload the cytosine nucleoside precipitate on the inclined plate 6, the staff only needs to start the second motor 20. Under the transmission action of the first bevel gear 18 and the second bevel gear 22, the screw rod 17 will be driven to rotate, and under the action of the screw rod 17, the closing plate 15 will move upward with the lifting seat 16.

[0031] Working principle of the utility model: When the device is used, the cytosine nucleoside mixture solution after the reaction is completed will be discharged into the box body 1 through the feed pipe 3. When the mixture solution passes through the inclined plate 6, the cytosine nucleoside precipitation inside the mixture solution can be filtered out through a plurality of filter holes 6. The waste liquid after filtration can be quickly discharged into the waste liquid treatment system through the sewage pipe 5;

[0032] When it is necessary to unload the product on the inclined plate 6, the staff only needs to start the second motor 20. Under the transmission action of the first bevel gear 18 and the second bevel gear 22, the screw rod 17 will be driven to rotate. Under the action of the screw rod 17, the closing plate 15 will move upward with the lifting seat 16, and then start the vibration motor 12 to make the sediment on the inclined plate 6 fall quickly into the discharge box 8.

[0033] Starting the first motor 14 can drive the conveying auger 13 to rotate. Under the action of the conveying auger 13 , the cytosine nucleoside powder precipitation will be driven to be discharged from the discharge rectangular tube 9 .

[0034] The circuits and controls involved in the present invention are all prior art and will not be described in detail here.

[0035] The above description is only an embodiment of the present invention, and does not limit the patent scope of the present invention. Any equivalent structure or equivalent process transformation made by using the contents of the specification and drawings of the present invention, or directly or indirectly applied in other related technical fields, are also included in the patent protection scope of the present invention.

Claims

1. A precipitation device for processing cytosine nucleoside, comprising a box (1) with a plurality of supporting legs (2) fixed at the bottom, characterized in that: The top of the box (1) is connected to two feed pipes (3), each of which is provided with a valve (4); the bottom of the box (1) is connected to a sewage discharge pipe (5); Two inclined plates (6) are symmetrically arranged inside the box body (1), a plurality of filter holes (7) are opened on the inclined plates (6), a discharge box (8) is arranged between the two inclined plates (6), and a discharge rectangular pipe (9) is arranged at the bottom of the discharge box (8) for communication.

2. A precipitation device for cytosine nucleoside processing and production according to claim 1, characterized in that: The top of the inclined plate (6) is movably connected to the inner wall of the box body (1), a support seat (10) is fixed inside the box body (1), a plurality of support springs (11) are fixed between the support seat (10) and the inclined plate (6), and a vibration motor (12) is arranged between the support seat (10) and the inclined plate (6).

3. A precipitation device for cytosine nucleoside processing and production according to claim 2, characterized in that: A conveying auger (13) is movably arranged inside the discharge box (8).

4. A precipitation device for cytosine nucleoside processing and production according to claim 3, characterized in that: A first motor (14) is installed on one side of the box body (1), and an output end of the first motor (14) is connected to the central axis of the conveying auger (13) via a coupling.

5. A precipitation device for cytosine nucleoside processing and production according to claim 4, characterized in that: Two closing plates (15) are arranged at intervals inside the box body (1), the closing plates (15) are arranged through the top of the box body (1), and the closing plates (15) are slidably connected to the top of the box body (1); The bottom of the closing plate (15) contacts the surface of the inclined plate (6), and a sealing gasket is provided at the bottom of the closing plate (15).

6. A precipitation device for cytosine nucleoside processing and production according to claim 5, characterized in that: A lifting seat (16) is fixed between the two closing plates (15), a screw rod (17) is movably arranged on the top of the box body (1), the top of the screw rod (17) passes through the lifting seat (16), and the screw rod (17) is threadedly connected to the lifting seat (16); A first bevel gear (18) is mounted on the top of the screw rod (17); a limit seat (19) and a second motor (20) are mounted on the top of the housing (1); a rotating shaft (21) is movably arranged on the limit seat (19) via a bearing; a second bevel gear (22) meshing with the first bevel gear (18) is mounted on one end of the rotating shaft (21); and the other end of the rotating shaft (21) is connected to the second motor (20) via a coupling.

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