Microsphere cleaning and screening device

Abstract

The utility model provides a microsphere cleaning and screening device which comprises a base, a barrel is arranged on the base, a cover is arranged on the barrel, the cover is connected with the barrel, and a screen assembly is arranged in the barrel. And an ultrasonic transducer and a vibration mechanism are arranged between the base and the barrel. According to the microsphere cleaning and screening device, the problem of low screening efficiency of microspheres in batch production is effectively solved, a batch operation tool is provided, and manpower is liberated; the problems of non-uniform manual microsphere screening operation and large batch-to-batch difference are effectively solved; the problem that when small-particle-size microspheres are screened manually, the service life of a screen is not long after the screen is blocked and cleaned manually and repeatedly is effectively solved. A vibration mode and an ultrasonic mode are provided, a large number of accumulated microspheres are cleaned through vibration of the vibration mechanism, and the microspheres accumulated in a pore channel are cleaned through ultrasonic treatment of the ultrasonic transducer.

Description

Technical Field

[0001] The utility model belongs to the field of microball cleaning equipment, in particular to a microball cleaning and screening device. Background Art

[0002] Magnetic microspheres are widely used in in vitro diagnosis, protein purification, cell screening, chemiluminescence, nucleic acid purification, etc. Some microspheres prepared by emulsion polymerization and suspension polymerization have a wide distribution of particle sizes, and the microspheres need to be screened by particle size. It is simple to screen large particles using a filter. When the particle size is less than 5μm, manual screening with a screen is inefficient, takes up a lot of manpower, the screening operation is not standardized, and the screen is easily blocked, resulting in an exponential increase in the difficulty of screening. Widely dispersed microspheres affect the extraction performance in practical applications, and the use of traditional manual screens to screen microspheres is inefficient and difficult to operate, with large batch-to-batch differences. The smaller the particle size, the more difficult the screening and the lower the efficiency.

[0003] The Chinese utility model patent with application number CN202011560660.7 discloses a microsphere screening device. The device does not use cleaning liquid immersion or ultrasonic assistance, and there is a problem of filter membrane clogging. The screening efficiency using low-frequency vibration alone decreases exponentially with the increase of the degree of clogging. Summary of the invention

[0004] In view of this, the utility model aims to overcome the defects in the prior art and proposes a microsphere cleaning and screening device.

[0005] In order to achieve the above object, the technical solution of the utility model is implemented as follows:

[0006] A microsphere cleaning and screening device comprises a base, a cylinder is arranged on the base, a cover is arranged on the cylinder, the cover is connected to the cylinder, a screen assembly is arranged in the cylinder; an ultrasonic transducer and a vibration mechanism are arranged between the base and the cylinder.

[0007] Furthermore, the cover body and the cylinder body are both provided with connecting ears, and the connecting ears of the cover body and the connecting ears of the cylinder body are connected by fixing screws.

[0008] Furthermore, the screen assembly includes a plurality of screens. A single screen has screens with different mesh sizes for replacement, and a metal screen is mainly used to ensure strength; a single screen has a unified feature, that is, it has the same extension frame to achieve multi-layer assembly (the extension frame is provided with screw holes); at the same time, the mesh size of the screen gradually increases.

[0009] Furthermore, the screen assembly includes a primary screen, a secondary screen and a tertiary screen, wherein the secondary screen is located outside the primary screen, and the tertiary screen is located outside the secondary screen. The primary screen is used to filter microspheres with too large particle size, the tertiary screen is used to filter microspheres with too small particle size, and the secondary screen is used to filter and obtain the target microspheres.

[0010] Furthermore, the primary screen, secondary screen and tertiary screen are all cylindrical structures and are provided with an extension frame at the top, the extension frame is located on the connecting ear of the cylinder, and the extension frame is located between the connecting ear of the cover body and the connecting ear of the cylinder; the outer diameters of the extension frames of the primary screen, secondary screen and tertiary screen are the same; the inner diameter of the primary screen is smaller than the inner diameter of the secondary screen, and the inner diameter of the secondary screen is smaller than the inner diameter of the tertiary screen.

[0011] Furthermore, a buffer spring is arranged between the base and the cylinder; an operation panel and a power switch are arranged on the base.

[0012] Furthermore, a pressure sensor is also arranged in the cylinder; a drain outlet is arranged at the bottom of the cylinder, and a water outlet valve is arranged on the drain outlet; and a liquid inlet is arranged on the cover.

[0013] Furthermore, the vibration mechanism includes an outer shell, a vibration cover is arranged on the top of the outer shell, the outer shell and the vibration cover are movably connected, a rotating motor is arranged on the outer shell, the rotating motor is connected to a rotating shaft, a plurality of oscillation components are arranged inside the outer shell, and the rotating shafts are all connected to the oscillation components.

[0014] Furthermore, the oscillation assembly includes an eccentric wheel group, a sleeve, a connecting rod, and a top block. The outer side of the eccentric wheel group is connected to the rotating shaft. The eccentric wheel group includes two eccentric wheels with the same structure. A connecting shaft is arranged between the eccentric wheels. The connecting shaft is located on one side of the center of the eccentric wheel. The sleeve is sleeved on the outer side of the connecting shaft. One end of the connecting rod is connected to the sleeve, and the other end is connected to the top block. The top block is located below the vibration cover. The centers of the eccentric wheels of adjacent eccentric wheel groups are staggered.

[0015] Furthermore, an outer platform is provided on the outer side of the vibration cover, the outer platform is located below the top of the outer shell, and a return spring is provided between the outer platform and the outer shell; a plurality of limit blocks are provided on the inner side of the vibration cover, and the connecting rod is located between the limit blocks.

[0016] Compared with the prior art, the utility model has the following advantages:

[0017] The microsphere cleaning and screening device described in the utility model effectively solves the problem of low screening efficiency of microspheres in batch production, provides a batch operation tool to liberate manpower; effectively solves the problem of inconsistent manual screening operation of microspheres and large batch differences; effectively solves the problem of short service life of the screen after repeated manual cleaning of the screen due to filter clogging during manual screening of small-size microspheres; provides two modes, oscillation and ultrasound, to clean a large number of accumulated microspheres through the oscillation of a vibration mechanism, and to clean the microspheres accumulated in the pores through ultrasound performed by an ultrasonic transducer. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] The accompanying drawings constituting a part of the present invention are used to provide a further understanding of the present invention. The illustrative embodiments of the present invention and their descriptions are used to explain the present invention and do not constitute an improper limitation on the present invention. In the accompanying drawings:

[0019] Figure 1 A schematic diagram of a microsphere cleaning and screening device according to an embodiment of the utility model;

[0020] Figure 2 A schematic diagram of a vibration mechanism according to an embodiment of the utility model;

[0021] Figure 3 It is a schematic diagram of the primary screen described in the embodiment of the utility model.

[0022] Description of reference numerals:

[0023] 1. Base; 11. Operation panel; 12. Power switch; 2. Cylinder; 21. Water outlet valve; 22. Connecting ear; 23. Pressure sensor; 3. Cover; 31. Liquid inlet; 4. Primary screen; 5. Secondary screen; 6. Tertiary screen; 61. Extension frame; 7. Buffer spring; 8. Ultrasonic transducer; 9. Vibration mechanism; 10. Fixing screw; 91. Vibration cover; 911. External platform; 912. Limit block; 92. Rotating motor; 93. Rotating shaft; 94. Eccentric wheel; 95. Sleeve; 96. Connecting rod; 97. Top block; 98. Reset spring; 99. External shell. DETAILED DESCRIPTION

[0024] It should be noted that, in the absence of conflict, the embodiments of the present invention and the features in the embodiments can be combined with each other.

[0025] In the description of the present utility model, it should be understood that the terms "center", "longitudinal", "lateral", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside" and the like indicate positions or positional relationships based on the positions or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present utility model and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on the present utility model. In addition, the terms "first", "second", etc. are only used for descriptive purposes, and cannot be understood as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Therefore, features defined as "first", "second", etc. may explicitly or implicitly include one or more of the features. In the description of the present utility model, unless otherwise specified, "multiple" means two or more.

[0026] In the description of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms "installation", "connection" and "connection" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be an indirect connection through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood by specific circumstances.

[0027] The present invention will be described in detail below with reference to the accompanying drawings and in combination with embodiments.

[0028] like Figure 1-3 As shown, a microsphere cleaning and screening device includes a base 1, a cylinder 2 is arranged on the base 1, a cover 3 is arranged on the cylinder 2, the cover 3 is connected to the cylinder 2, and a screen assembly is arranged in the cylinder 2; an ultrasonic transducer 8 and a vibration mechanism 9 are arranged between the base 1 and the cylinder 2.

[0029] The cover body 3 and the cylinder body 2 are both provided with connecting ears 22 , and the connecting ears 22 of the cover body 3 are connected with the connecting ears 22 of the cylinder body 2 via fixing screws 10 .

[0030] The screen assembly includes a primary screen 4, a secondary screen 5 and a tertiary screen 6, wherein the secondary screen 5 is located outside the primary screen 4, and the tertiary screen 6 is located outside the secondary screen 5. The primary screen 4, the secondary screen 5 and the tertiary screen 6 are all cylindrical structures and are provided with an extension frame 61 at the top, wherein the extension frame 61 is located on the connecting ear 22 of the cylinder 2, and the extension frame 61 is located between the connecting ear 22 of the cover 3 and the connecting ear 22 of the cylinder 2; the outer diameters of the extension frame 61 of the primary screen 4, the secondary screen 5 and the tertiary screen 6 are the same; the inner diameter of the primary screen 4 is smaller than the inner diameter of the secondary screen 5, and the inner diameter of the secondary screen 5 is smaller than the inner diameter of the tertiary screen 6.

[0031] A buffer spring 7 is also provided between the base 1 and the cylinder 2 ; an operation panel 11 and a power switch 12 are provided on the base 1 .

[0032] A pressure sensor 23 is also arranged in the cylinder 2 ; a drain port is arranged at the bottom of the cylinder 2 , and a water outlet valve 21 is arranged on the drain port; and a liquid inlet 31 is arranged on the cover 3 .

[0033] The vibration mechanism 9 includes an outer shell 99, a vibration cover 91 is arranged on the top of the outer shell 99, the outer shell 99 and the vibration cover 91 are movably connected, a rotating motor 92 is arranged on the outer shell 99, and the rotating motor 92 is connected to a rotating shaft 93. A plurality of oscillation components are arranged inside the outer shell 99, and the rotating shafts 93 are all connected to the oscillation components. The oscillation assembly includes an eccentric wheel 94 group, a sleeve 95, a connecting rod 96, and a top block 97. The outer side of the eccentric wheel 94 group is connected to the rotating shaft 93. The eccentric wheel 94 group includes two eccentric wheels 94 with the same structure. A connecting shaft is arranged between the eccentric wheels 94. The connecting shaft is located on one side of the center of the eccentric wheel 94. The sleeve 95 is sleeved on the outer side of the connecting shaft. One end of the connecting rod 96 is connected to the sleeve 95, and the other end is connected to the top block 97. The top block 97 is located below the vibration cover 91. The centers of the eccentric wheels 94 of adjacent eccentric wheel 94 groups are arranged alternately. The outer side of the vibration cover 91 is provided with an outer platform 911, which is located below the top of the outer shell 99. A reset spring 98 is arranged between the outer platform 911 and the outer shell 99. A plurality of limit blocks 912 are arranged on the inner side of the vibration cover 91, and the connecting rod 96 is located between the limit blocks 912.

[0034] After the rotating motor 92 is turned on, the rotating motor 92 drives the rotating shaft 93 to rotate, and the rotating shaft 93 drives the eccentric wheel 94 to rotate, thereby driving the movement of the sleeve 95. Since the bottom of the top block 97 is rotatably connected to the connecting rod 96, the top block 97 performs a lifting movement under the limit of the limit block 912. When the top block 97 rises, it lifts the vibration cover 91. At this time, the reset spring 98 is in a compressed state. After the top block 97 descends, the vibration cover 91 also descends, and the reset spring 98 gradually relaxes. In addition, the centers of the eccentric wheels 94 of adjacent eccentric wheel 94 groups are staggered. The adjacent top blocks 97 alternately replace the vibration cover 91, so that the lifting frequency is significantly improved, which has a vibration effect.

[0035] When the device is in use, cleaning liquid needs to be added to submerge the bottom of the primary screen 4. The good dispersion of microspheres in the cleaning liquid helps the screening work. The main working principle for small particle size screening is as follows: when the cleaning liquid is ultrasonic, small particles fall from the screen. When the material accumulates, the vibration mechanism 9 is activated to break up the microspheres in each cavity. After the screening work is completed, the water outlet valve 21 can be used to release the cleaning liquid, and the cleaning liquid can be added again for multiple flushing to achieve the purpose of cleaning.

[0036] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention should be included in the protection scope of the present invention.

Claims

1. A microsphere cleaning and screening device, characterized in that: It comprises a base, a cylinder is arranged on the base, a cover is arranged on the cylinder, the cover is connected to the cylinder, a screen assembly is arranged in the cylinder; an ultrasonic transducer and a vibration mechanism are arranged between the base and the cylinder.

2. The microsphere cleaning and screening device according to claim 1, characterized in that: The cover body and the cylinder body are both provided with connecting ears, and the connecting ears of the cover body and the connecting ears of the cylinder body are connected by fixing screws.

3. The microsphere cleaning and screening device according to claim 1, characterized in that: The screen assembly comprises a plurality of screens.

4. The microsphere cleaning and screening device according to claim 1, characterized in that: The screen assembly comprises a primary screen, a secondary screen and a tertiary screen. The secondary screen is located outside the primary screen, and the tertiary screen is located outside the secondary screen.

5. The microsphere cleaning and screening device according to claim 4, characterized in that: The primary screen, secondary screen and tertiary screen are all cylindrical structures and are provided with an extension frame at the top, the extension frame is located on the connecting ear of the cylinder, and the extension frame is located between the connecting ear of the cover body and the connecting ear of the cylinder; the outer diameters of the extension frames of the primary screen, secondary screen and tertiary screen are the same; the inner diameter of the primary screen is smaller than the inner diameter of the secondary screen, and the inner diameter of the secondary screen is smaller than the inner diameter of the tertiary screen.

6. The microsphere cleaning and screening device according to claim 1, characterized in that: A buffer spring is also arranged between the base and the cylinder; an operation panel and a power switch are arranged on the base.

7. The microsphere cleaning and screening device according to claim 1, characterized in that: A pressure sensor is also arranged in the cylinder; a drain port is arranged at the bottom of the cylinder, and a water outlet valve is arranged on the drain port; and a liquid inlet is arranged on the cover.

8. The microsphere cleaning and screening device according to claim 1, characterized in that: The vibration mechanism includes an outer shell, a vibration cover is arranged on the top of the outer shell, the outer shell and the vibration cover are movably connected, a rotating motor is arranged on the outer shell, the rotating motor is connected to a rotating shaft, a plurality of oscillation components are arranged inside the outer shell, and the rotating shafts are all connected to the oscillation components.

9. The microsphere cleaning and screening device according to claim 8, characterized in that: The oscillation assembly includes an eccentric wheel group, a sleeve, a connecting rod, and a top block. The outer side of the eccentric wheel group is connected to the rotating shaft. The eccentric wheel group includes two eccentric wheels with the same structure. A connecting shaft is arranged between the eccentric wheels. The connecting shaft is located on one side of the center of the eccentric wheel. The sleeve is sleeved on the outer side of the connecting shaft. One end of the connecting rod is connected to the sleeve, and the other end is connected to the top block. The top block is located below the vibration cover. The centers of the eccentric wheels of adjacent eccentric wheel groups are staggered.

10. The microsphere cleaning and screening device according to claim 9, characterized in that: An outer platform is arranged on the outer side of the vibration cover, the outer platform is located below the top of the outer shell, and a return spring is arranged between the outer platform and the outer shell; a plurality of limit blocks are arranged on the inner side of the vibration cover, and the connecting rod is located between the limit blocks.

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