Sealing kit

Abstract

The utility model provides a sealing kit. The sealing kit comprises a kit body and a first cover body arranged at the top of the kit body, a plurality of reagent grooves are formed in the kit body, the reagent grooves are distinguished one by one through groove plates in the kit body, a channel is formed in the bottom of the kit body, and the channel is communicated with all the reagent grooves; the first cover body is arranged at the top of the kit body and connected with the kit body, a plurality of through holes are formed in the first cover body, the through holes correspond to the reagent grooves one to one, and the through holes are provided with detachable sealing structures; and after the box body is inclined, the residual reagent can be collected to the reagent groove at the end part of the box body, and then is poured out from the reagent groove at the end part. According to the utility model, operation steps can be simplified, time is saved, and detection efficiency is improved; when only a small amount of reagent is left in the reagent tank, the reagent can be directly transferred into the same reagent tank and then poured into other reagents with the same components, which are not completely used up, through the corners for subsequent use, so that the problem that the operation is difficult when a plurality of reagent tanks are poured out is avoided.

Description

Technical Field

[0001] The utility model relates to the technical field of sample detection, in particular to a sealed reagent kit. Background Art

[0002] In the field of sample testing, a test kit is a container for storing reagents. When storing and transporting reagents, the test kit is required to be sealed to prevent leakage of the reagents; when the reagents are in use, the sampling device is inserted into the test kit to absorb the reagents. In the prior art, in order to improve efficiency when adding reagents, the fully automatic nucleic acid extraction equipment uses bottled reagents to be manually poured into the strip test kit, which is then absorbed by a multi-channel pipette and injected into a deep-well plate. The unused reagents must be poured back into the bottle for storage after testing, and put into use after the tail reagents are collected multiple times. When using semi-automatic nucleic acid extraction equipment, the reagents to be used need to be packaged in the deep-well plate in advance and sealed with aluminum film. When in use, the aluminum film is removed and placed in the corresponding position for nucleic acid extraction. The problems with this type of method are:

[0003] Bottled reagents need to be manually poured into the strip test kit before use. The strip test kit has a narrow opening, so liquids are easily spilled outside the test kit. In addition, the strip test kit and the carrier are vertical strips, which are prone to tipping risks on the desktop.

[0004] Unused reagents need to be poured back into the bottle for storage after the test is completed, and the reagents need to be transferred before and after use, which is cumbersome and time-consuming, and reduces operational efficiency.

[0005] The kit disclosed in the prior art is also mainly used in automatic nucleic acid extraction equipment, and may have some of the defects mentioned above. Utility Model Content

[0006] The purpose of the utility model is to provide an improved test kit to address the deficiencies in the above-mentioned background technology, so as to reduce the risks of spilling and tipping caused by multiple transfers of reagents during testing, and at the same time, after multiple tests, the tailings can be easily and quickly transferred to the same reagent tank for new testing.

[0007] In order to achieve the above-mentioned object, the utility model provides a sealed reagent kit, comprising a box body and a first cover body arranged on the top of the box body;

[0008] A plurality of reagent tanks are arranged in the box body, and the reagent tanks are distinguished one by one by tank plates in the box body. A channel is formed at the bottom of the box body, and the channel is connected to each of the reagent tanks;

[0009] The first cover is disposed on the top of the box body and connected to the box body. A plurality of through holes are formed on the first cover. The through holes correspond to the reagent tanks one by one. The through holes are provided with a detachable sealing structure.

[0010] Wherein, after the box body is tilted, the remaining reagent can be collected into the reagent tank located at the end of the box body, and then poured out from the reagent tank at the end.

[0011] Furthermore, a step surface is formed at the lower portion of the first cover body, the step surface matches the top of the box body, and the step surface and the top of the box body are connected and sealed by hot-melt welding.

[0012] Furthermore, the sealing structure is a second cover.

[0013] Furthermore, the second cover body includes a cover plate and a plurality of sealing plugs arranged on the lower surface of the cover plate, and the sealing plugs match the shape of the through holes so as to be inserted into the through holes to seal and maintain.

[0014] Furthermore, the sealing structure is a sealing film arranged on the upper surface of the first cover body, and the sealing film and the first cover body are hot-melt welded to form a sealing state.

[0015] Furthermore, the through hole is a circular hole or a U-shaped hole.

[0016] Furthermore, the sealing reagent kit also includes a supporting carrier, which includes a bottom plate and side plates, the spacing between the two side plates matches the thickness of the box body, the bottom plate is provided with a positioning groove, and the bottom of the box body is provided with a positioning cone surface matching the positioning groove.

[0017] Furthermore, the side plates of the support carrier and the outer surface of the box body are respectively provided with matching foolproof limit grooves and foolproof limit blocks.

[0018] Furthermore, color markings are provided at corresponding positions of the box body and the supporting carrier, and the color markings are used to quickly guide the box body to be placed at a correct position of the supporting carrier.

[0019] Furthermore, a label containing reagent information is provided on the side surface of the box body, and the label is used for scanning by a scanning device to read the reagent information.

[0020] The above solution of the utility model has the following beneficial effects:

[0021] The sealed test kit provided by the utility model has reagents that have been pre-packed into the various reagent slots of the box body before leaving the factory. When using, the user does not need to transfer the reagents from the reagent bottles to the deep-well plate, etc., thus avoiding the risks of spilling and tipping. The sealed test kit can be easily opened to remove the reagents through the arrangement of the box body, the first cover body, the second cover body, etc., and the unused reagents can be stored after being sealed by the sealing plug without further transfer. There is no need to transfer the reagents before and after the test, thus simplifying the operation steps, saving time, and improving the test efficiency.

[0022] The sealed reagent kit provided by the utility model can directly transfer a small amount of reagent in a reagent tank to the same reagent tank when only a small amount of reagent remains, and then pour it into other unused reagents of the same component by using the corners for subsequent use, thus avoiding the difficulty of pouring out multiple reagent tanks;

[0023] The sealing test kit provided by the utility model ensures that the operator can quickly and correctly place the box body on the support carrier without making mistakes through the support, positioning, foolproof structure, color identification, etc. of the box body by the support carrier, which can simplify the detection process, shorten the detection time, and improve the user experience;

[0024] Other beneficial effects of the present invention will be described in detail in the subsequent specific implementation sections. BRIEF DESCRIPTION OF THE DRAWINGS

[0025] Figure 1 It is an exploded schematic diagram of the overall structure of the utility model;

[0026] Figure 2 This is a schematic diagram of the internal structure of the box body of the utility model;

[0027] Figure 3 This is a schematic diagram of the first cover structure of the utility model;

[0028] Figure 4 This is a schematic diagram of the second cover structure of the utility model;

[0029] Figure 5 It is a schematic diagram of the support carrier of the utility model.

[0030] [Description of Reference Numerals]

[0031] 1-box body; 2-first cover body; 3-second cover body; 4-support carrier; 5-reagent tank; 6-step surface; 7-through hole; 8-cover plate; 9-sealing plug; 10-slot plate; 11-channel; 12-positioning groove; 13-positioning cone surface; 14-foolproofing limit groove; 15-foolproofing limit block. DETAILED DESCRIPTION

[0032] In order to make the technical problems, technical solutions and advantages to be solved by the utility model clearer, the following will be described in detail with reference to the accompanying drawings and specific embodiments. Obviously, the described embodiments are part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the utility model. In addition, the technical features involved in the different embodiments of the utility model described below can be combined with each other as long as they do not conflict with each other.

[0033] In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc., indicating the orientation or positional relationship, are based on the orientation or positional relationship shown in the drawings, and are only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as limiting the present invention. In addition, the terms "first", "second", and "third" are used for descriptive purposes only, and cannot be understood as indicating or implying relative importance.

[0034] In the description of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms "installation", "connection" and "connection" should be understood in a broad sense, for example, it can be a locking connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be an indirect connection through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0035] like Figure 1 As shown, an embodiment of the utility model provides a sealed reagent kit, which includes a box body 1, a first cover body 2, a second cover body 3 and a supporting carrier 4.

[0036] At the same time Figure 2 As shown, the box body 1 itself is in the shape of a long strip, and a plurality of reagent tanks 5 are arranged in the box body 1. The reagent tanks 5 are arranged in a single row along the box body 1, and are suitable for most current sample tests, such as the test of the semi-automatic nucleic acid extraction equipment mentioned in the background technology (of course, multiple rows can also be used). The reagent tank 5 has a certain depth, which can store sufficient reagents for multiple sampling tests or reactions, and a single transfer of sufficient reagents for testing or reaction.

[0037] It should be noted that the arrangement and depth of the reagent tank 5 are matched with the pipetting module (such as a pipette gun) of the pipetting device. The pipetting module can be inserted into the deeper position of the reagent tank 5 to fully remove and transfer the reagent in the reagent tank 5. If the number of samples tested in a single test is small, a small portion of the reagent in the reagent tank 5 will remain. This portion can still be tested or reacted, but in order to meet the needs of more sample tests, it is necessary to adopt other methods to transfer it to other reagent tanks 5 so that the collected reagent volume can meet the needs of more sample tests. Of course, in order to avoid affecting the accuracy of the test or reaction, each time the pipetting module removes the reagent, a new contact component needs to be replaced for the next removal to avoid contamination of the reagent.

[0038] At the same time Figure 3 As shown, the first cover 2 is arranged on the top of the box body 1 and is fixedly arranged with the box body 1, thereby forming an integral structure. Specifically, a step surface 6 is formed at the lower part of the first cover 2. Through the setting of the step surface 6, the lower part of the first cover 2 can be inserted into the top of the box body 1, and a stable connection is formed by hot-melt welding to ensure sealing. This method is convenient for processing the box body 1 and the first cover 2, and the box body 1 and the first cover 2 can be made of hard plastic material. When assembling, the two can be directly inserted into place and then welded and sealed.

[0039] The first cover 2 is provided with a plurality of through holes 7, which correspond one to one with each reagent slot 5 of the box body 1, so that the liquid transfer module can be inserted into the reagent slot 5 from the through hole 7 to transfer the reagent. Figure 4 As shown, the second cover body 3 is matched with the first cover body 2, and is used to seal the through hole 7 on the first cover body 2. Specifically in the present embodiment, the second cover body 3 includes a cover plate 8 and a plurality of sealing plugs 9 arranged on the lower surface of the cover plate 8. Among them, the cover plate 8 is also made of hard rubber material, and the sealing plug 9 is made of soft rubber material, and matches the shape of the through hole 7 on the first cover body 2, and has a wavy pattern at the same time, so as to be able to fully retract and the like. When the second cover body 3 is covered on the first cover body 2, the sealing plug 9 is inserted into each through hole 7 of the first cover body 2 to seal it, that is, each reagent tank 5 is sealed, and the sealing of the sealed reagent box is ensured when storing and transporting reagents. Based on the elastic engagement of the sealing plug 9 at the position of the through hole 7 (which can also be regarded as an interference fit), a sealed state can be maintained.

[0040] It should be noted that the through hole 7 on the first cover body 2 can be a circular hole or a Figure 3 The U-shaped hole shown is not specifically limited here and can be set based on actual needs, as long as the shape of the sealing plug 9 is consistent with the through hole 7.

[0041] As a major improvement of the present embodiment, each reagent tank 5 in the box body 1 is distinguished one by one by a slot plate 10, and the bottom of the slot plate 10 does not fully extend to the bottom of the box body 1, so that an integrated channel 11 is formed at the bottom of the box body 1, that is, the channel 11 connects the bottoms of each reagent tank 5. Therefore, when the sealed reagent box is in a sealed state, the channel 11 also remains connected. After removing the reagent once or several times for detection or reaction, the reagent can be made to flow into the same reagent tank 5 at the end through the channel by tilting the box body 1 in the sealed state of the box body 1. Then, the box body 1 is tilted and the reagent is poured into other unused reagents of the same component for subsequent use by relying on the corner position and the corresponding through hole 7, avoiding the difficulty of operation when pouring out multiple reagent tanks 5.

[0042] In this embodiment, the interior of the first cover body 2 is hollowed out, and each through hole 7 is formed with a rim toward the first cover body 2. This method saves more materials and reduces weight than a solid setting (except for the through hole 7). When the remaining reagents are collected in the end reagent tank 5, and then poured out by the corner position, the rim of the through hole 7 corresponding to the end reagent tank 5 may make the reagents remaining unable to be completely poured out. Therefore, the rim is still used to fit the inner wall at this position, that is, a solid setting, such as Figure 5 shown.

[0043] In another implementation of this embodiment, the second cover 3 may not be provided, and a PP-AL composite film may be used to seal the upper surface of the first cover 2. The PP-AL composite film is a kind of sealing film, and is formed into a stable sealing state with the first cover 2 by hot-melt welding. When the reagent needs to be removed, the PP-AL composite film can be directly torn off.

[0044] It is understandable that such a long strip-shaped box body 1 is prone to tipping over to both sides of the long side when placed for various operations, causing the reagent to pour out, polluting the environment, etc. Therefore, in this embodiment, the box body 1 is supported and kept stable by the supporting carrier 4. Figure 5 As shown. The support frame 4 includes a bottom plate and side plates. The distance between the two side plates matches the thickness of the box body 1, so that the box body 1 can be placed between the two side plates. A positioning groove 12 is provided on the bottom plate, and a positioning cone 13 matching the positioning groove 12 is provided at the bottom of the box body 1. Figure 2As shown, the positioning cone 13 is in a form of gradually narrowing from top to bottom, so that the box body 1 can be stably placed on the support carrier 4 and various operations can be performed through the engagement of the positioning cone 13 with the positioning groove 12. It can be understood that the reagent tank 5 where the positioning cone 13 is located is also a part of the channel 11. Of course, in order to make it more convenient for the box body 1 to be placed in the support carrier 4, the box body 1 itself also adopts a form of slightly wider at the top and slightly narrower at the bottom, so that it can be easily inserted between the two side panels and cooperate with the positioning cone 13 to form a stable state.

[0045] Considering that the operation of placing the box body 1 on the support carrier 4 is more convenient, and considering that multiple reagents of different components may be used in the same test. Therefore, as a further improvement of this embodiment, matching foolproof limit grooves 14 and foolproof limit blocks 15 are respectively provided on the side panels of the support carrier 4 and the outer surface of the box body 1 (the positions of the foolproof limit grooves 14 and the foolproof limit blocks 15 of different reagent components are different). In the process of placing the box body 1 into the support carrier 4, it is only necessary to align the foolproof limit block 15 with the foolproof limit groove 14 and then put it in. At this time, the positioning cone 13 at the bottom of the box body 1 is also aligned with the positioning groove 12. If the wrong box body 1 is placed in the support frame 4, the box body cannot be loaded, reminding the user to check whether the reagent components are correct, thereby avoiding the operation of loading the wrong reagent components.

[0046] As a further improvement of this embodiment, color markings may be provided at corresponding positions of the box body 1 and the support carrier 4 , which can also serve to quickly guide the operator to place the box body 1 at the correct position of the support carrier 4 .

[0047] It should also be noted that, based on actual usage requirements, a label with reagent information can also be affixed to the side surface of the box body 1. During operation, the corresponding equipment will scan and read the reagent information, automatically determine whether the reagent position is correct, whether it is within the validity period, record the reagent batch number, etc., to ensure the traceability of the reagent, and it is also a further determination of the accurate placement of the box body 1.

[0048] In summary, in the sealed test kit provided in this embodiment, the reagents have been pre-packed into the various reagent slots 5 of the box body 1 before leaving the factory. When using, the user does not need to transfer the reagents from the reagent bottles to the deep well plate, etc., to avoid the risks of spilling, dumping, etc.; the unused reagents can be stored after being sealed by the sealing plug 9, without further transfer, and there is no need to transfer the reagents before and after the test, which simplifies the operation steps, saves time, and improves the detection efficiency; when there is only a small amount of reagent left in the reagent slot 5, it can be directly transferred to the same reagent slot 5, and then poured into other unused reagents of the same component for subsequent use by relying on the corners, avoiding operational difficulties when pouring out multiple reagent slots 5, and through the support, positioning, fool-proof structure, color identification, etc. of the box body 1 by the support carrier 4 to ensure that the operator can quickly and correctly place the box body 1 on the support carrier 4 without making mistakes, which can simplify the detection process, shorten the detection time, and improve the user experience.

[0049] The technical features of the above embodiments may be combined arbitrarily. To make the description concise, not all possible combinations of the technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0050] The above embodiments only express several implementation methods of the present application, and the descriptions thereof are relatively specific and detailed, but they cannot be understood as limiting the scope of the application. It should be pointed out that, for a person of ordinary skill in the art, several variations and improvements can be made without departing from the concept of the present application, and these all belong to the protection scope of the present application. Therefore, the protection scope of the present application shall be subject to the attached claims.

Claims

1. A sealed reagent kit, characterized in that: It comprises a box body (1) and a first cover body (2) arranged on the top of the box body (1); A plurality of reagent tanks (5) are arranged in the box body (1), and the reagent tanks (5) are distinguished one by one by tank plates (10) in the box body (1). A channel (11) is formed at the bottom of the box body (1), and the channel (11) is connected to each of the reagent tanks (5); The first cover body (2) is arranged on the top of the box body (1) and connected to the box body (1); a plurality of through holes (7) are opened on the first cover body (2); the through holes (7) correspond to the reagent tanks (5) one by one; and the through holes (7) are provided with a detachable sealing structure; When the box body (1) is tilted, the remaining reagent can be collected in the reagent tank (5) at the end of the box body (1), and then poured out from the reagent tank (5) at the end.

2. The sealing kit according to claim 1, characterized in that A step surface (6) is formed at the lower part of the first cover body (2), and the step surface (6) matches the top of the box body (1). The step surface (6) and the top of the box body (1) are connected and sealed by hot-melt welding.

3. The sealing kit according to claim 1, characterized in that: The sealing structure is a second cover (3).

4. The sealing kit according to claim 3, characterized in that: The second cover body (3) comprises a cover plate (8) and a plurality of sealing plugs (9) arranged on the lower surface of the cover plate (8); the sealing plugs (9) match the shape of the through hole (7) so as to be inserted into the through hole (7) to seal and maintain.

5. The sealing kit according to claim 1, characterized in that: The sealing structure is a sealing film arranged on the upper surface of the first cover body (2), and the sealing film and the first cover body (2) are hot-melt welded to form a sealed state.

6. The sealing kit according to claim 1, characterized in that: The through hole (7) is a circular hole or a U-shaped hole.

7. The sealing kit according to claim 1, characterized in that: The sealing reagent kit further comprises a supporting frame (4), wherein the supporting frame (4) comprises a bottom plate and a side plate, wherein the distance between the two side plates matches the thickness of the box body (1), the bottom plate is provided with a positioning groove (12), and the bottom of the box body (1) is provided with a positioning cone surface (13) matching the positioning groove (12).

8. The sealing kit according to claim 7, characterized in that: The side plates of the supporting carrier (4) and the outer surface of the box body (1) are respectively provided with matching foolproof limit grooves (14) and foolproof limit blocks (15).

9. The sealing kit according to claim 7, characterized in that: Color markings are provided at corresponding positions of the box body (1) and the supporting carrier (4), and the color markings are used to quickly guide the box body (1) to be placed at a correct position on the supporting carrier (4).

10. The sealing kit according to any one of claims 7 to 9, characterized in that: A label containing reagent information is arranged on the side surface of the box body (1), and the label is used for scanning by a scanning device to read the reagent information.

Images